#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Validation of a simple extraction procedure for bisphenol A identification from human plasma


Autoři: Idha Arfianti Wiraagni aff001;  Mustafa Ali Mohd aff003;  Rusdi bin Abd Rashid aff004;  Didi Erwandi bin Mohamad Haron aff003
Působiště autorů: Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia aff001;  Department of Forensic Medicine and Medicolegal, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia aff002;  Shimadzu‐UM Center for Xenobiotics Studies (SUCXeS), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia aff003;  Department of Psychological Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia aff004
Vyšlo v časopise: PLoS ONE 14(10)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0221774

Souhrn

The general population is exposed to bisphenol A (BPA) orally, parenterally, transdermally, and environmentally as a result of the use of BPA in food packaging, plastics, and personal care products. The majority of the population nowadays (91–99%) has detectable levels of BPA inside their body. In this study, we successfully performed an inexpensive, rapid, and simple protein precipitation procedure for extraction of BPA from human plasma, followed by analysis by LC-MS/MS. This method was specifically developed for handling large numbers of samples with minimum cost and volume of sample. The developed method was accurate, precise, and reproducible for quantification of BPA from human plasma samples in the concentration range of 10–2000 ng/mL. The method was performed on samples from 150 healthy volunteers who were enrolled in the study. The mean of observed BPA level was 2.22 ± 9.91 ng/mL. Higher BPA levels were observed for females compare to that of males (p-value = 0.002), the BPA levels were higher in participants 33 years of age and older compared to those less than 33 years of age (p-value = 0.000), then the BPA levels higher in subjects with tap water as source of drinking (p-value = 0.005). This method may be valuable for general risk assessment of BPA for a large and varied population because of its efficiency and economical aspects.

Klíčová slova:

Blood – Blood plasma – Plasma proteins – Pollutants – Protein extraction – Quality control – Urine – Plastics


Zdroje

1. Rochester JR, Bolden AL. Bisphenol S and F: A Systematic Review and Comparison of the Hormonal Activity of Bisphenol A Substitutes. Environmental Health Perspectives. 2015; doi: 10.1289/ehp.1408989 25775505

2. Zhang J, Li X, Zhou L, Wang L, Zhou Q, Huang X. Analysis of effects of a new environmental pollutant, bisphenol A, on antioxidant systems in soybean roots at different growth stages. Scientific Reports. 2016;6. doi: 10.1038/srep23782 27030053

3. Nam S-H, Seo Y-M, Kim M-G. Bisphenol A migration from polycarbonate baby bottle with repeated use. Chemosphere. 2010;79: 949–952. doi: 10.1016/j.chemosphere.2010.02.049 20334893

4. Buck Louis GM, Peterson CM, Chen Z, Croughan M, Sundaram R, Stanford J, et al. Bisphenol A and phthalates and endometriosis: the Endometriosis: Natural History, Diagnosis and Outcomes Study. Fertility and Sterility. 2013;100: 162–169.e2. doi: 10.1016/j.fertnstert.2013.03.026 23579005

5. Li D-K, Zhou Z, Miao M, He Y, Wang J, Ferber J, et al. Urine bisphenol-A (BPA) level in relation to semen quality. Fertility and Sterility. 2011;95: 625–630.e4. doi: 10.1016/j.fertnstert.2010.09.026 21035116

6. Meeker JD, Ehrlich S, Toth TL, Wright DL, Calafat AM, Trisini AT, et al. Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinic. Reproductive Toxicology. 2010;30: 532–539. doi: 10.1016/j.reprotox.2010.07.005 20656017

7. Mok-Lin E, Ehrlich S, Williams PL, Petrozza J, Wright DL, Calafat AM, et al. Urinary bisphenol A concentrations and ovarian response among women undergoing IVF. International Journal of Andrology. 2010;33: 385–393. doi: 10.1111/j.1365-2605.2009.01014.x 20002217

8. Wolff MS, Britton JA, Boguski L, Hochman S, Maloney N, Serra N, et al. Environmental exposures and puberty in inner-city girls. Environmental Research. 2008;107: 393–400. doi: 10.1016/j.envres.2008.03.006 18479682

9. Wolff MS, Engel SM, Berkowitz GS, Ye X, Silva MJ, Zhu C, et al. Prenatal Phenol and Phthalate Exposures and Birth Outcomes. Environmental Health Perspectives. 2008;116: 1092–1097. doi: 10.1289/ehp.11007 18709157

10. Braun JM, Yolton K, Dietrich KN, Hornung R, Ye X, Calafat AM, et al. Prenatal Bisphenol A Exposure and Early Childhood Behavior. Environmental Health Perspectives. 2009;117: 1945–1952. doi: 10.1289/ehp.0900979 20049216

11. Shen Y, Zheng Y, Jiang J, Liu Y, Luo X, Shen Z, et al. Higher Urinary Bisphenol A Concentration Is Associated with Unexplained Recurrent Miscarriage Risk: Evidence from a Case-Control Study in Eastern China. Gibert Y, editor. PLOS ONE. 2015;10: e0127886. doi: 10.1371/journal.pone.0127886 26011304

12. Andrianou XD, Gängler S, Piciu A, Charisiadis P, Zira C, Aristidou K, et al. Human Exposures to Bisphenol A, Bisphenol F and Chlorinated Bisphenol A Derivatives and Thyroid Function. Carvalho DP de, editor. PLOS ONE. 2016;11: e0155237. doi: 10.1371/journal.pone.0155237 27783680

13. Xia W, Jiang Y, Li Y, Wan Y, Liu J, Ma Y, et al. Early-Life Exposure to Bisphenol A Induces Liver Injury in Rats Involvement of Mitochondria-Mediated Apoptosis. Nadal A, editor. PLoS ONE. 2014;9: e90443. doi: 10.1371/journal.pone.0090443 24587367

14. Vandenberg LN, Hauser R, Marcus M, Olea N, Welshons WV. Human exposure to bisphenol A (BPA). Reproductive Toxicology. 2007;24: 139–177. doi: 10.1016/j.reprotox.2007.07.010 17825522

15. Asimakopoulos AG, Thomaidis NS, Koupparis MA. Recent trends in biomonitoring of bisphenol A, 4-t-octylphenol, and 4-nonylphenol. Toxicology Letters. 2012;210: 141–154. doi: 10.1016/j.toxlet.2011.07.032 21888958

16. Zhang Z, Alomirah H, Cho H-S, Li Y-F, Liao C, Minh TB, et al. Urinary Bisphenol A Concentrations and Their Implications for Human Exposure in Several Asian Countries. Environmental Science & Technology. 2011;45: 7044–7050. doi: 10.1021/es200976k 21732633

17. Volkel W. Quantitation of Bisphenol A and Bisphenol A Glucuronide in Biological Samples by High Performance Liquid Chromatography-Tandem Mass Spectrometry. Drug Metabolism and Disposition. 2005;33: 1748–1757. doi: 10.1124/dmd.105.005454 16103135

18. Markham DA, Waechter JM Jr, Wimber M, Rao N, Connolly P, Chuang JC, et al. Development of a method for the determination of bisphenol A at trace concentrations in human blood and urine and elucidation of factors influencing method accuracy and sensitivity. Journal of analytical toxicology. 2010;34: 293–303. doi: 10.1093/jat/34.6.293 20663281

19. Liao C, Liu F, Alomirah H, Loi VD, Mohd MA, Moon H-B, et al. Bisphenol S in Urine from the United States and Seven Asian Countries: Occurrence and Human Exposures. Environmental Science & Technology. 2012;46: 6860–6866. doi: 10.1021/es301334j 22620267

20. Ihde ES, Zamudio S, Loh JM, Zhu Y, Woytanowski J, Rosen L, et al. Application of a novel mass spectrometric (MS) method to examine exposure to Bisphenol-A and common substitutes in a maternal fetal cohort. Human and Ecological Risk Assessment: An International Journal. 2018;24: 331–346. doi: 10.1080/10807039.2017.1381831

21. Aris A. Estimation of bisphenol A (BPA) concentrations in pregnant women, fetuses and nonpregnant women in Eastern Townships of Canada. Reproductive Toxicology. 2014;45: 8–13. doi: 10.1016/j.reprotox.2013.12.006 24378374

22. Kuklenyik Z, Ekong J, Cutchins CD, Needham LL, Calafat AM. Simultaneous Measurement of Urinary Bisphenol A and Alkylphenols by Automated Solid-Phase Extractive Derivatization Gas Chromatography/Mass Spectrometry. Analytical Chemistry. 2003;75: 6820–6825. doi: 10.1021/ac0303158 14670041

23. Vitku J, Chlupacova T, Sosvorova L, Hampl R, Hill M, Heracek J, et al. Development and validation of LC–MS/MS method for quantification of bisphenol A and estrogens in human plasma and seminal fluid. Talanta. 2015;140: 62–67. doi: 10.1016/j.talanta.2015.03.013 26048824

24. Mohammed SA, Eissa MS, Ahmed HM. Simple protein precipitation extraction technique followed by validated chromatographic method for linezolid analysis in real human plasma samples to study its pharmacokinetics. Journal of Chromatography B. 2017;1043: 235–240. doi: 10.1016/j.jchromb.2016.09.042 27720354

25. Owczarek K, Kubica P, Kudłak B, Rutkowska A, Konieczna A, Rachoń D, et al. Determination of trace levels of eleven bisphenol A analogues in human blood serum by high performance liquid chromatography–tandem mass spectrometry. Science of The Total Environment. 2018;628–629: 1362–1368. doi: 10.1016/j.scitotenv.2018.02.148 30045557

26. Lehmler H-J, Liu B, Gadogbe M, Bao W. Exposure to Bisphenol A, Bisphenol F, and Bisphenol S in U.S. Adults and Children: The National Health and Nutrition Examination Survey 2013–2014. ACS Omega. 2018;3: 6523–6532. doi: 10.1021/acsomega.8b00824 29978145

27. Lorber M, Schecter A, Paepke O, Shropshire W, Christensen K, Birnbaum L. Exposure assessment of adult intake of bisphenol A (BPA) with emphasis on canned food dietary exposures. Environment International. 2015;77: 55–62. doi: 10.1016/j.envint.2015.01.008 25645382

28. Corrales J, Kristofco LA, Steele WB, Yates BS, Breed CS, Williams ES, et al. Global Assessment of Bisphenol A in the Environment: Review and Analysis of Its Occurrence and Bioaccumulation. Dose-Response. 2015;13: 155932581559830. doi: 10.1177/1559325815598308 26674671

29. Testai E, Hartemann P, Rodríguez-Farre E, Rastogi SC, Bustos J, Gundert-Remy U, et al. The safety of the use of bisphenol A in medical devices. Regulatory Toxicology and Pharmacology. 2016;79: 106–107. doi: 10.1016/j.yrtph.2016.01.014 26851507

30. Hormann AM, vom Saal FS, Nagel SC, Stahlhut RW, Moyer CL, Ellersieck MR, et al. Holding Thermal Receipt Paper and Eating Food after Using Hand Sanitizer Results in High Serum Bioactive and Urine Total Levels of Bisphenol A (BPA). Carpenter DO, editor. PLoS ONE. 2014;9: e110509. doi: 10.1371/journal.pone.0110509 25337790

31. Liao C, Kannan K. A Survey of Alkylphenols, Bisphenols, and Triclosan in Personal Care Products from China and the United States. Archives of Environmental Contamination and Toxicology. 2014;67: 50–59. doi: 10.1007/s00244-014-0016-8 24639116

32. Sohail MS. Gender differences in mall shopping: a study of shopping behaviour of an emerging nation. Journal of Marketing and Consumer Behaviour in Emerging Markets.: 11.

33. Rouhani MH, Mirseifinezhad M, Omrani N, Esmaillzadeh A, Azadbakht L. Fast Food Consumption, Quality of Diet, and Obesity among Isfahanian Adolescent Girls. Journal of Obesity. 2012;2012: 1–8. doi: 10.1155/2012/597924 22619703

34. Galloway T, Cipelli R, Guralnik J, Ferrucci L, Bandinelli S, Corsi AM, et al. Daily Bisphenol A Excretion and Associations with Sex Hormone Concentrations: Results from the InCHIANTI Adult Population Study. Environmental Health Perspectives. 2010;118: 1603–1608. doi: 10.1289/ehp.1002367 20797929

35. Kim IH, Kisseleva T, Brenner DA. Aging and liver disease: Current Opinion in Gastroenterology. 2015;31: 184–191. doi: 10.1097/MOG.0000000000000176 25850346


Článek vyšel v časopise

PLOS One


2019 Číslo 10
Nejčtenější tento týden
Nejčtenější v tomto čísle
Kurzy

Zvyšte si kvalifikaci online z pohodlí domova

KOST
Koncepce osteologické péče pro gynekology a praktické lékaře
nový kurz
Autoři: MUDr. František Šenk

Sekvenční léčba schizofrenie
Autoři: MUDr. Jana Hořínková

Hypertenze a hypercholesterolémie – synergický efekt léčby
Autoři: prof. MUDr. Hana Rosolová, DrSc.

Svět praktické medicíny 5/2023 (znalostní test z časopisu)

Imunopatologie? … a co my s tím???
Autoři: doc. MUDr. Helena Lahoda Brodská, Ph.D.

Všechny kurzy
Kurzy Podcasty Doporučená témata Časopisy
Přihlášení
Zapomenuté heslo

Zadejte e-mailovou adresu, se kterou jste vytvářel(a) účet, budou Vám na ni zaslány informace k nastavení nového hesla.

Přihlášení

Nemáte účet?  Registrujte se

#ADS_BOTTOM_SCRIPTS#