#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Impact of visual impairment on physical activity in early and late age-related macular degeneration


Autoři: Manuel Heinemann aff001;  Susanne G. Welker aff001;  Jeany Q. Li aff001;  Maximilian W. M. Wintergerst aff001;  Gabrielle N. Turski aff001;  Christopher A. Turski aff001;  Jan H. Terheyden aff001;  Matthias M. Mauschitz aff001;  Frank G. Holz aff001;  Robert P. Finger aff001
Působiště autorů: University of Bonn, Department for Ophthalmology, Ernst- Abbe- Straße, Bonn, Germany aff001
Vyšlo v časopise: PLoS ONE 14(10)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0222045

Souhrn

Background

Modifiable risk factors for age-related macular degeneration (AMD) include smoking, nutrition and likely physical activity (PA). Levels of PA, however, are impacted by any visual impairment which makes the assessment of any association with AMD difficult.

Purpose

To assess the impact of visual impairment under both high and low luminance conditions on levels of PA in early and late AMD.

Methods

Ninety participants with early to late AMD underwent a clinical assessment including conventional best-corrected visual acuity, low luminance visual acuity, contrast sensitivity and the Moorfields acuity test. PA was recorded using a wrist-worn accelerometer (GENEActiv, Activeinsights) on seven consecutive days. Patient characteristics were compared with the Wilcoxon rank-sum test and determinants of moderate-to-vigorous-PA (MVPA) were assessed using linear regression models.

Results

Mean age was 73.9 ± 8.5 years (range 50–89) and 47 subjects (52.2%) were women. Average MVPA time was longer in the early (355.1 ± 252.0 minutes/week) compared to the late AMD group (162.2 ± 134.6 minutes/week; p<0.001). Using linear regression, age [β = -0.25; 95% confidence interval (CI): -12.9; -0.8, p = 0.028] and AMD stage (β = -0.28; 95% CI: -230.9, -25.0; p = 0.015) but not visual impairment on any of the employed tests were associated with MVPA (minutes/week).

Conclusions

We found late AMD to be associated with reduced PA. As performance on any of the visual tests was not associated with PA, this association cannot entirely be explained by functional impairment. More research is needed to further explore the association of PA and AMD as PA may be a potentially modifiable risk factor.

Klíčová slova:

Exercise – Luminance – Macular degeneration – Medical risk factors – Physical activity – Vision – Visual acuity – Visual impairments


Zdroje

1. Lim LS, Mitchell P, Seddon JM, Holz FG, Wong TY. Age-related macular degeneration. Lancet. 2012; 379: 1728–1738. doi: 10.1016/S0140-6736(12)60282-7 22559899

2. Bourne RRA, Jonas JB, Bron AM, Cicinelli MV, Das A, Flaxman SR, et al. Prevalence and causes of vision loss in high-income countries and in Eastern and Central Europe in 2015: magnitude, temporal trends and projections. Br J Ophthalmol. 2018. doi: 10.1136/bjophthalmol-2017-311258 29545417

3. Ferris FL3, Wilkinson CP, Bird A, Chakravarthy U, Chew E, Csaky K, et al. Clinical classification of age-related macular degeneration. Ophthalmology. 2013; 120: 844–851. doi: 10.1016/j.ophtha.2012.10.036 23332590

4. Fenwick EK, Cheung GCM, Gan AT, Tan G, Lee SY, Wong D, et al. Change in vision-related quality of life and influencing factors in Asians receiving treatment for neovascular age-related macular degeneration. Br J Ophthalmol. 2018; 102: 377–382. doi: 10.1136/bjophthalmol-2017-310532 28659392

5. Finger RP, Fenwick E, Marella M, Dirani M, Holz FG, Chiang PP-C, et al. The impact of vision impairment on vision-specific quality of life in Germany. Invest Ophthalmol Vis Sci. 2011; 52: 3613–3619. doi: 10.1167/iovs.10-7127 21357395

6. Gopinath B, Liew G, Burlutsky G, Mitchell P. Physical activity and the 15-year incidence of age-related macular degeneration. Invest Ophthalmol Vis Sci. 2014; 55: 7799–7803. doi: 10.1167/iovs.14-15575 25389200

7. Klein R, Lee KE, Gangnon RE, Klein BEK. Relation of smoking, drinking, and physical activity to changes in vision over a 20-year period: the Beaver Dam Eye Study. Ophthalmology. 2014; 121: 1220–1228. doi: 10.1016/j.ophtha.2014.01.003 24594095

8. Knudtson MD, Klein R, Klein BEK. Physical activity and the 15-year cumulative incidence of age-related macular degeneration: the Beaver Dam Eye Study. Br J Ophthalmol. 2006; 90: 1461–1463. doi: 10.1136/bjo.2006.103796 17077116

9. Loprinzi PD, Swenor BK, Ramulu PY. Age-Related Macular Degeneration Is Associated with Less Physical Activity among US Adults: Cross-Sectional Study. PLoS One. 2015; 10: e0125394. doi: 10.1371/journal.pone.0125394 25933421

10. McGuinness MB, Karahalios A, Simpson JA, Guymer RH, Robman LD, Hodge AM, et al. Past physical activity and age-related macular degeneration: the Melbourne Collaborative Cohort Study. Br J Ophthalmol. 2016; 100: 1353–1358. doi: 10.1136/bjophthalmol-2015-307663 26787681

11. McGuinness MB, Le J, Mitchell P, Gopinath B, Cerin E, Saksens NTM, et al. Physical Activity and Age-related Macular Degeneration: A systematic literature review and meta-analysis. Am J Ophthalmol. 2017. doi: 10.1016/j.ajo.2017.05.016 28549846

12. Colijn JM, den Hollander AI, Demirkan A, Cougnard-Gregoire A, Verzijden T, Kersten E, et al. Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration: Evidence from the EYE-RISK and European Eye Epidemiology Consortia. Ophthalmology. 2018. doi: 10.1016/j.ophtha.2018.09.045 30315903

13. Raimundo M, Mira F, Cachulo MdL, Barreto P, Ribeiro L, Farinha C, et al. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study—report 3. Acta Ophthalmol. 2018. doi: 10.1111/aos.13775 30218481

14. Smith W, Mitchell P. Family history and age-related maculopathy: The Blue Mountains Eye Study. Australian and New Zealand Journal of Ophthalmology; 26: 203–206. doi: 10.1111/j.1442-9071.1998.tb01311.x 9717749

15. AgeRelated_Eye_Disease_Study_Reasearch_Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol. 2001; 119: 1417–1436. doi: 10.1001/archopht.119.10.1417 11594942

16. Paffenbarger RS, JR, Hyde RT, Wing AL, Hsieh CC. Physical activity, all-cause mortality, and longevity of college alumni. N Engl J Med. 1986; 314: 605–613. doi: 10.1056/NEJM198603063141003 3945246

17. Johnson R, Robertson W, Towey M, Stewart-Brown S, Clarke A. Changes over time in mental well-being, fruit and vegetable consumption and physical activity in a community-based lifestyle intervention: a before and after study. Public Health. 2017; 146: 118–125. doi: 10.1016/j.puhe.2017.01.012 28404463

18. Kerr J, Anderson C, Lippman SM. Physical activity, sedentary behaviour, diet, and cancer: an update and emerging new evidence. Lancet Oncol. 2017; 18: e457–e471. doi: 10.1016/S1470-2045(17)30411-4 28759385

19. Loprinzi PD, Pariser G, Ramulu PY. Accelerometer-assessed sedentary and physical activity behavior and its association with vision among U.S. adults with diabetes. J Phys Act Health. 2014; 11: 1156–1161. doi: 10.1123/jpah.2012-0354 24184561

20. McMahon EM, Corcoran P, O'Regan G, Keeley H, Cannon M, Carli V, et al. Physical activity in European adolescents and associations with anxiety, depression and well-being. Eur Child Adolesc Psychiatry. 2017; 26: 111–122. doi: 10.1007/s00787-016-0875-9 27277894

21. Aune D, Norat T, Leitzmann M, Tonstad S, Vatten LJ. Physical activity and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis. Eur J Epidemiol. 2015; 30: 529–542. doi: 10.1007/s10654-015-0056-z 26092138

22. Hamer M, Lavoie KL, Bacon SL. Taking up physical activity in later life and healthy ageing: the English longitudinal study of ageing. Br J Sports Med. 2014; 48: 239–243. doi: 10.1136/bjsports-2013-092993 24276781

23. McGuinness MB, Finger RP, Karahalios A, Guymer RH, English DR, Chong EW, et al. Age-related macular degeneration and mortality: the Melbourne Collaborative Cohort Study. Eye (Lond). 2017; 31: 1345–1357. doi: 10.1038/eye.2017.139 28820184

24. Subhi Y, Sorensen TL. Physical activity patterns in patients with early and late age-related macular degeneration. Dan Med J. 2016; 63.

25. Nguyen AM, Arora KS, Swenor BK, Friedman DS, Ramulu PY. Physical activity restriction in age-related eye disease: a cross-sectional study exploring fear of falling as a potential mediator. BMC Geriatr. 2015; 15: 64. doi: 10.1186/s12877-015-0062-8 26062727

26. Willis JR, Jefferys JL, Vitale S, Ramulu PY. Visual impairment, uncorrected refractive error, and accelerometer-defined physical activity in the United States. Arch Ophthalmol. 2012; 130: 329–335. doi: 10.1001/archopthalmol.2011.1773 22411662

27. Dillon CB, Fitzgerald AP, Kearney PM, Perry IJ, Rennie KL, Kozarski R, et al. Number of Days Required to Estimate Habitual Activity Using Wrist-Worn GENEActiv Accelerometer: A Cross-Sectional Study. PLoS One. 2016; 11: e0109913. doi: 10.1371/journal.pone.0109913 27149674

28. Heinemann M, Welker SG, Holz FG, Finger RP. Physical activity in older persons with eye diseases. Applicability of wrist-worn accelerometer. Ophthalmologe. 2018. doi: 10.1007/s00347-018-0688-y 29564538

29. Esliger DW, Rowlands AV, Hurst TL, Catt M, Murray P, Eston RG. Validation of the GENEA Accelerometer. Med Sci Sports Exerc. 2011; 43: 1085–1093. doi: 10.1249/MSS.0b013e31820513be 21088628

30. Ferris FL3, Kassoff A, Bresnick GH, Bailey I. New visual acuity charts for clinical research. Am J Ophthalmol. 1982; 94: 91–96. 7091289

31. Shah N, Dakin SC, Dobinson S, Tufail A, Egan CA, Anderson RS. Visual acuity loss in patients with age-related macular degeneration measured using a novel high-pass letter chart. Br J Ophthalmol. 2016; 100: 1346–1352. doi: 10.1136/bjophthalmol-2015-307375 26846435

32. Elliott DB, Sanderson K, Conkey A. The reliability of the Pelli-Robson contrast sensitivity chart. Ophthalmic Physiol Opt. 1990; 10: 21–24. 2330208

33. Williams PT. Prospective study of incident age-related macular degeneration in relation to vigorous physical activity during a 7-year follow-up. Invest Ophthalmol Vis Sci. 2009; 50: 101–106. doi: 10.1167/iovs.08-2165 18566466

34. Sengupta S, Nguyen AM, van Landingham SW, Solomon SD, Do DV, Ferrucci L, et al. Evaluation of real-world mobility in age-related macular degeneration. BMC Ophthalmol. 2015; 15: 9. doi: 10.1186/1471-2415-15-9 25636376

35. Munch IC, Linneberg A, Larsen M. Precursors of age-related macular degeneration: associations with physical activity, obesity, and serum lipids in the inter99 eye study. Invest Ophthalmol Vis Sci. 2013; 54: 3932–3940. doi: 10.1167/iovs.12-10785 23652489

36. Rim TH, Kim HK, Kim JW, Lee JS, Kim DW, Kim SS. A Nationwide Cohort Study on the Association Between Past Physical Activity and Neovascular Age-Related Macular Degeneration in an East Asian Population. JAMA Ophthalmol. 2018; 136: 132–139. doi: 10.1001/jamaophthalmol.2017.5682 29242918

37. Adjei NK, Brand T. Investigating the associations between productive housework activities, sleep hours and self-reported health among elderly men and women in western industrialised countries. BMC public health. 2018; 18: 110. doi: 10.1186/s12889-017-4979-z 29320997

38. Wu Z, Ayton LN, Luu CD, Guymer RH. Longitudinal changes in microperimetry and low luminance visual acuity in age-related macular degeneration. JAMA Ophthalmol. 2015; 133: 442–448. doi: 10.1001/jamaophthalmol.2014.5963 25632841

39. Dimitrov PN, Robman LD, Varsamidis M, Aung KZ, Makeyeva GA, Guymer RH, et al. Visual function tests as potential biomarkers in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2011; 52: 9457–9469. doi: 10.1167/iovs.10-7043 22003115

40. Wu Z, Guymer RH, Finger RP. Low luminance deficit and night vision symptoms in intermediate age-related macular degeneration. Br J Ophthalmol. 2016; 100: 395–398. doi: 10.1136/bjophthalmol-2015-306621 26250520

41. Chandramohan A, Stinnett SS, Petrowski JT, Schuman SG, Toth CA, Cousins SW, et al. Visual function measures in early and intermediate age-related macular degeneration. Retina. 2016; 36: 1021–1031. doi: 10.1097/IAE.0000000000001002 26925551

42. Hartman SJ, Nelson SH, Weiner LS. Patterns of Fitbit Use and Activity Levels Throughout a Physical Activity Intervention: Exploratory Analysis from a Randomized Controlled Trial. JMIR Mhealth Uhealth. 2018; 6: e29. doi: 10.2196/mhealth.8503 29402761


Článek vyšel v časopise

PLOS One


2019 Číslo 10
Nejčtenější tento týden
Nejčtenější v tomto čísle
Kurzy

Zvyšte si kvalifikaci online z pohodlí domova

KOST
Koncepce osteologické péče pro gynekology a praktické lékaře
nový kurz
Autoři: MUDr. František Šenk

Sekvenční léčba schizofrenie
Autoři: MUDr. Jana Hořínková

Hypertenze a hypercholesterolémie – synergický efekt léčby
Autoři: prof. MUDr. Hana Rosolová, DrSc.

Svět praktické medicíny 5/2023 (znalostní test z časopisu)

Imunopatologie? … a co my s tím???
Autoři: doc. MUDr. Helena Lahoda Brodská, Ph.D.

Všechny kurzy
Kurzy Podcasty Doporučená témata Časopisy
Přihlášení
Zapomenuté heslo

Zadejte e-mailovou adresu, se kterou jste vytvářel(a) účet, budou Vám na ni zaslány informace k nastavení nového hesla.

Přihlášení

Nemáte účet?  Registrujte se

#ADS_BOTTOM_SCRIPTS#