Myocardial function in patients with anomalous left coronary artery from the pulmonary artery syndrome: A long-term speckle tracking echocardiographic study


Autoři: Alicja Dąbrowska-Kugacka aff001;  Karolina Dorniak aff002;  Jarosław Meyer-Szary aff003;  Agnieszka Herrador Rey aff003;  Ewa Lewicka aff001;  Katarzyna Ostrowska aff004;  Joanna Kwiatkowska aff003
Působiště autorů: Department of Cardiology and Electrotherapy, Medical University of Gdansk, Gdansk, Poland aff001;  Department of Noninvasive Cardiac Diagnostics, Medical University of Gdansk, Gdansk, Poland aff002;  Department of Pediatric Cardiology and Congenital Heart Disease, Medical University of Gdansk, Gdansk, Poland aff003;  Department of Cardiology, Polish Mother’s Memorial Hospital–Research Institute, Lodz, Poland aff004
Vyšlo v časopise: PLoS ONE 14(10)
Kategorie: Research Article
doi: 10.1371/journal.pone.0223227

Souhrn

Background

Anomalous origin of the left coronary artery (LCA) from the pulmonary artery (ALCAPA) is a rare congenital heart disease. Retrograde flow from the right coronary artery (RCA) through natural collaterals to the low-pressure main pulmonary artery causes extensive ischemia. Limited data concerning the extent of permanent myocardial damage and functional recovery after surgical repair in the long-term follow-up is available.

Aim

Determination of the incidence of incipient myocardial dysfunction in ALCAPA patients in the long-term observation using tissue Doppler and speckle tracking echocardiography.

Methods and results

Eighteen ALCAPA patients after surgical repair (at median age of 7 months, range 3–167) underwent echocardiographic examination after (median) 17 years. All but 4 patients in NYHA class II presented well at follow-up. No narrowing in proximal LCA was detected in color Doppler. The initial (pre-surgical) left ventricular (LV) ejection fraction of 33±17% almost normalized to 55±6%, but was lower than in the age, sex and body surface area matched control group: 62±5% (p<0.001). At follow-up, LV global longitudinal strain (LS): -15.8±3.3% vs -21.9±1.7%; right ventricular LS: -20.6±3.9% vs -24.9±4.6%; left atrial LS: 27.7±4.3% vs 41.0±11.5%; right atrial LS: 26.8±7.4% vs 44.0±7.9% and early pulsed wave to tissue Doppler mitral filling ratio (E/E’): 8.1±2.6 vs 5.8±1.3 were impaired in the ALCAPA population in comparison to the control group (p<0.01 for all comparisons). LV radial and circumferential strain did not differ between groups. Mean LS in the ALCAPA patients in the RCA region was -19.0±4.4%, while in the LCA region -13.8±7.3% (p<0.00001).

Conclusions

Despite good clinical condition and normalized LV ejection fraction in ALCAPA patients after surgical repair in the long-term follow-up, the diastolic and longitudinal systolic function of all cardiac chambers remained impaired, especially in the LCA region. Lifelong surveillance of repaired ALCAPA patients is needed.

Klíčová slova:

Coronary heart disease – Echocardiography – Ischemia – Pulmonary arteries – Stenosis – Surgical and invasive medical procedures – Surgical repair – Papillary muscles


Zdroje

1. Farouk A, Zahka K, Siwik E, Golden A, Karimi M, Uddin M, et al. Anomalous origin of the left coronary artery from the right pulmonary artery. J Card Surg. 2009; 24: 49–54. doi: 10.1111/j.1540-8191.2008.00622.x 19120675

2. Lange R, Vogt M, Horer J, Hörer J, Cleuziou J, Menzel A, et al. Long-term results of repair of anomalous origin of the left coronary artery from the pulmonary artery. Ann Thorac Surg. 2007; 83: 1463–71. doi: 10.1016/j.athoracsur.2006.11.005 17383358

3. Alexi-Meskishvili V, Nasseri BA, Nordmeyer S, Schmitt B, Weng YG, Böttcher W, et al. Repair of anomalous origin of the left coronary artery from the pulmonary artery in infants and children. J Thorac Cardiovasc Surg. 2011; 142: 868–74. doi: 10.1016/j.jtcvs.2011.04.006 21665229

4. Hoashi T, Kagisaki K, Okuda N, Shiraishi I, Yagihara T, Ichikawa H. Indication of Takeuchi technique for patients with anomalous origin of the left coronary artery from the pulmonary artery. Circ J. 2013; 77: 1202–1207. doi: 10.1253/circj.cj-12-1321 23392121

5. Ling Y, Bhushan S, Fan Q and Tang M. Midterm outcome after surgical correction of anomalous left coronary artery from the pulmonary artery. Journal of Cardiothoracic Surgery. 2016, 11: 137. doi: 10.1186/s13019-016-0397-z

6. Naimo PS, Fricke TA, d’Udekem Y, Cochrane AD, Bullock A, Robertson T, et al. Surgical intervention for anomalous origin of left coronary artery from the pulmonary artery in children: A long-term follow-up. Ann Thorac Surg. 2016; 101: 1842–8. doi: 10.1016/j.athoracsur.2015.11.020 26897320

7. Kazmierczak PA, Ostrowska K, Dryzek P, Moll JA, Moll JJ. Repair of anomalous origin of the left coronary artery from the pulmonary artery in infants. Interact Cardiovasc Thor Surg. 2013; 16: 797–801.

8. Ben Ali W, Metton O, Roubertie F, Pouard P, Sidi D, Raisky O, et al. Anomalous origin of the left coronary artery from the pulmonary artery: late results with special attention to the mitral valve. Eur J Cardiothorac Surg. 2009; 36: 244–249. doi: 10.1016/j.ejcts.2009.03.014 19372048

9. Cabrera AG, Chen DW, Pignatelli RH, Khan MS, Jeewa A, Mery CM, et al. Outcomes of anomalous left coronary artery from pulmonary artery repair: beyond normal function. Ann Thorac Surg. 2015; 99: 1342–7. doi: 10.1016/j.athoracsur.2014.12.035 25725925

10. Browne LP, Kearney D, Taylor MD, Chung T, Slesnick TC, Nutting AC, et al. ALCAPA: the role of myocardial viability studies in determining prognosis. Pediatr Radiol. 2010; 40: 163–7. doi: 10.1007/s00247-009-1412-5 19795113

11. Schmitt B, Bauer S, Kutty S, Nordmeyer S, Nasseri B, Berger F, et al. Myocardial perfusion, scarring, and function in anomalous left coronary artery from the pulmonary artery syndrome: a long-term analysis using magnetic resonance imaging. Ann Thorac Surg. 2014; 98: 1425–36. doi: 10.1016/j.athoracsur.2014.05.031 25130077

12. Kanoh M, Inai K, Shinohara T, Tomimatsu H, Nakanishi T. Outcomes from anomalous origin of the left coronary artery from the pulmonary artery repair: long-term complications in relations to residual myocardial abnormalities. J Cardiol. 2017; 70: 498–503. doi: 10.1016/j.jjcc.2017.03.008 28427867

13. Zheng J, Ding W, Xiao Y, Jin M, Zhang G, Cheng P, et al. Anomalous origin of the left coronary artery from the pulmonary artery in children: 15 years experience. Pediatr Cardiol. 2011; 32: 24–31. doi: 10.1007/s00246-010-9798-2 20976445

14. Prakash A, Powell AJ, Krishnamurthy R, Geva T. Magnetic resonance imaging evaluation of myocardial perfusion and viability in congenital and acquired pediatric heart disease. Am J Cardiol. 2004; 93: 657–61. doi: 10.1016/j.amjcard.2003.11.045 14996605

15. Kwiatkowska J, Herrador Rey A, Meyer-Szary J, Dorniak K, Ostrowska K, Wałdoch A, Kozłowski D, Dabrowska-Kugacka A. Longterm outcome after surgical repair of anomalous origin of the left coronary artery from the pulmonary artery– 24 years of experience. Kardiol Pol Ahead of print / doi: 10.33963/KP.14816 31066728

16. Di Salvo G, Eyskens B, Claus P, D'hooge J, Bijnens B, Suys B, et al. Late post-repair ventricular function in patients with origin of the left main coronary artery from the pulmonary trunk. Am J Cardiol. 2004; 93: 506–8. doi: 10.1016/j.amjcard.2003.10.059 14969638

17. American Hospital Association; (2003-02-01). AHA: Advisory: HIPAA Updated Guidelines for Releasing Information on the Condition of Patients. American Hospital Association. Retrieved and archived on 2008-01-28

18. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015; 28: 1–39. doi: 10.1016/j.echo.2014.10.003 25559473

19. Pettersen MD, Du W, Skeens ME, and Humes RA. Regression equations for calculation of z scores of cardiac structures in a large cohort of healthy infants, children, and adolescents: an echocardiographic study. J Am Soc Echocardiogr. 2008; 21: 922–934. doi: 10.1016/j.echo.2008.02.006 18406572

20. Nagueh SF, Smiseth OA, Appleton CP, Byrd BF 3rd, Dokainish H, Edvardsen T, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging European Heart Journal–Cardiovascular Imaging. 2016; 17: 1321–1360.

21. Marcus KA, Mavinkurve-Groothius A MC, Barends M, van Dijk A, Feuth T, de Korte C. Reference values for myocardial two-dimensional strain echocardiography in a healthy pediatric and young adult cohort. J Am Soc Echocardiogr. 2011; I6: 625–636.

22. Yingchoncharoen T, Agarwal S, Popovi ZB, Marwick TH. Normal ranges of left ventricular strain: a meta-analysis. J Am Soc Echocardiogr. 2013; 26: 185–91. doi: 10.1016/j.echo.2012.10.008 23218891

23. Castaldi B, Vida V, Reffo E, Padalino M, Daniels Q, Stellin G et al. Speckle tracking in ALCAPA patients after surgical repair as predictor of residual coronary disease. Pediatr Cardiol 2017; 38:794–800 doi: 10.1007/s00246-017-1583-z 28214964

24. Parizek P, Haman L, Harrer J, et al. Bland-White-Garland syndrome in adults: sudden cardiac death as a first symptom and long-term follow-up after successful resuscitation and surgery. Europace. 2010; 12:1338–1340. doi: 10.1093/europace/euq087 20348142

25. Maes A, Flameng W, Nuyts J, Borgers M, Shivalkar B, Ausma J, et al. Histological alterations in chronically hypoperfused myocardium: correlations with PET findings. Circulation. 1994; 90: 735–745. doi: 10.1161/01.cir.90.2.735 8044942

26. Gorcsan J, Tanaka H. Echocardiographic assessment of myocardial strain. J Am Coll Cardiol. 2011; 58: 1401–13. doi: 10.1016/j.jacc.2011.06.038 21939821

27. El-Menyar A, Galzerano D, Asaad N, Al-Mulla A, Arafa S, Al Suwaidi J. Detection of myocardial dysfunction in the presence of normal ejection fraction. J Cardiovasc Med. 2007; 8: 923–33.

28. Dandel M, Lehmkuhl H, Knosalla C, Suramelashvili N, Hetzer R. Strain and strain rate imaging by echocardiography—basic concepts and clinical applicability. Curr Cardiol Rev. 2009; 5: 133–48. doi: 10.2174/157340309788166642 20436854

29. Mertens L, Weidemann F, Sutherland GR. Left ventricular function before and after repair of an anomalous left coronary artery arising from the pulmonary trunk. Cardiol Young. 2001; 11: 79–83. 11233402

30. Di Salvo G, Siblini G, Issa Z, Mohammed H, Hazeem A, Pergola V, et al. Left ventricular mechanics in patients with abnormal origin of the left main coronary artery from the pulmonary trunk late after successful repair. Cardiology. 2017; 136: 71–76. doi: 10.1159/000447961 27562944

31. Secinaro A, Ntsinjana H, Tann O, Schuler PK, Muthurangu V, Hughes M, et al. Cardiovascular magnetic resonance findings in repaired anomalous left coronary artery to pulmonary artery connection (ALCAPA). J Cardiovasc Magn Reson. 2011; 16: 13–27.

32. Ginde S, Earing MG, Bartz PJ, Cava JR, Tweddell JS. Late complications after Takeuchi repair of anomalous left coronary artery from the pulmonary artery: case series and review of literature. Pediatr Cardiol. 2012; 33: 1115–23. doi: 10.1007/s00246-012-0260-5 22438016


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2019 Číslo 10