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Self-reported and experimentally induced self-disgust is heightened in Parkinson’s disease: Contribution of behavioural symptoms


Autoři: Marianna Tsatali aff001;  Paul G. Overton aff002;  Ana B. Vivas aff003
Působiště autorů: South East European Research Center, SEERC, Thessaloniki, Greece aff001;  Psychology Department, University of Sheffield, Sheffield, United Kingdom aff002;  Psychology Department, The University of Sheffield International Faculty, City College, Thessaloniki, Greece aff003
Vyšlo v časopise: PLoS ONE 14(10)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0223663

Souhrn

Parkinson’s disease (PD) is associated with deficits in the recognition and expression of basic emotions, although self-reported levels of the self-conscious emotions shame and embarrassment are higher. However, one self-conscious emotion—self-disgust–which has been shown to have a negative impact on psychological wellbeing, has not been investigated in PD before. Here we employed self-report measures of self-conscious emotions, and an emotion induction paradigm involving images of the self, and narrated personal vignettes of instances when patients with PD (and controls) found themselves disgusting. We found that self-reported and induced levels of self-disgust were higher in PD patients than in matched controls, and that trait self-disgust was specifically related to disorders of impulse control in PD patients. Given the link between self-disgust and impaired psychological wellbeing, and the prevalence of anxiety and depression in PD, self-disgust might make a useful therapeutic target for psychological interventions in the condition.

Klíčová slova:

Anxiety – Cognitive impairment – Depression – Emotions – Face recognition – Impulsivity – Parkinson disease – Patients


Zdroje

1. Stern MB. The clinical characteristics of Parkinson’s disease and parkinsonian syndromes: diagnosis and assessment. In: Stern MB, Hurtig HI, editors. The comprehensive management of Parkinson’s disease. New York: PMA Publishing Company; 1988. pp. 3–50.

2. Gelb DJ, Oliver E, Gilman S. Diagnostic criteria for Parkinson disease. Arch Neurol. 1999; 56(1): 33–39. doi: 10.1001/archneur.56.1.33 9923759

3. Gallagher DA, Lees AJ, Schrag A. What are the most important nonmotor symptoms in patients with Parkinson’s disease and are we missing them? Mov Disord. 2010;25(15): 2493–2500. doi: 10.1002/mds.23394 20922807

4. Gray HM, Tickle-Degnen L. A meta-analysis of performance on emotion recognition tasks in Parkinson’s disease. Neuropsychol. 2010;24(2): 176–91.

5. Péron J, Dondaine T, Le Jeune F, Grandjean D, Vérin M. Emotional processing in Parkinson’s disease: a systematic review. Mov Disord. 2012; 27(2): 186–199. doi: 10.1002/mds.24025 22162004

6. Sotgiu I, Rusconi ML. Investigating emotions in Parkinson’s disease: what we know and what we still don’t know. Front Psychol. 2013;4: 336. doi: 10.3389/fpsyg.2013.00336 23772218

7. Alexander GE, De Long MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci. 1986;9(1): 357–381.

8. Kan Y, Kawamura M, Hasegawa Y, Mochizuki S, Nakamura K. Recognition of emotion from facial, prosodic and written verbal stimuli in Parkinson’s disease. Cortex. 2002;38(4): 623–630. doi: 10.1016/s0010-9452(08)70026-1 12465672

9. Yip J, Lee T, Ho S, Tsang K, Li L. Emotion recognition in patients with idiopathic Parkinson’s disease. Mov Disord. 2003;18(10): 1115–1122. doi: 10.1002/mds.10497 14534914

10. Schröder C, Möbes J, Schütze M, Szymanowski F, Nager W, Bangert M, et al. Perception of emotional speech in Parkinson’s disease. Mov Disord. 2006;21(10):1774–1778. doi: 10.1002/mds.21038 16830324

11. Dujardin K, Blairy S, Defebvre L, Duhem S, Noël Y, Hess U, et al. Deficits in decoding emotional facial expressions in Parkinson’s disease. Neuropsychologia. 2004;42(2):239–250. doi: 10.1016/s0028-3932(03)00154-4 14644109

12. Suzuki A, Hoshino T, Shigemasu K, Kawamura M. Disgust-specific impairment of facial expression recognition in Parkinson’s disease. Brain. 2006;129(3):707–717.

13. Lawrence AD, Goerendt IK, Brooks DJ. Impaired recognition of facial expressions of anger in Parkinson’s disease patients acutely withdrawn from dopamine replacement therapy. Neuropsychologia. 2007;45(1):65–74. doi: 10.1016/j.neuropsychologia.2006.04.016 16780901

14. Clark US, Neargarder S, Cronin-Golomb A. Specific impairments in the recognition of emotional facial expressions in Parkinson’s disease. Neuropsychologia. 2008;46(9): 2300–2309. doi: 10.1016/j.neuropsychologia.2008.03.014 18485422

15. Sprengelmeyer R, Young AW, Mahn K, Schroeder U, Woitalla D, Büttner T, et al. Facial expression recognition in people with medicated and unmedicated Parkinson’s disease. Neuropsychologia. 2003;41(8): 1047–1057. doi: 10.1016/s0028-3932(02)00295-6 12667540

16. Blonder LX, Gur RE, Gur RC. The effects of right and left parkinsonism on prosody. Brain Lang. 1989;36(2):193–207. doi: 10.1016/0093-934x(89)90061-8 2920285

17. Borod JC, Welkowitz J, Alpert M, Brozgold AZ, Martin C, Peselow E, et al. Parameters of emotional processing in neuropsychiatric disorders: conceptual issues and a battery of tests. J Commun Disord. 1990;23(4–5): 247–271. 2246382

18. Caekebeke JF, Jennekens-Schinkel A, van der Linden ME, Buruma OJ, Roos RA. The interpretation of dysprosody in patients with Parkinson’s disease. J Neurol Neurosurg Psychiatry. 1991;54(2): 145–148. doi: 10.1136/jnnp.54.2.145 2019840

19. Möbes J, Joppich G, Stiebritz F, Dengler R, Schröder C. Emotional speech in Parkinson’s disease. Mov Disord. 2008;23(6): 824–829. doi: 10.1002/mds.21940 18307245

20. Madeley P, Ellis AW, Mindham RHS. Facial expression and Parkinson’s disease. Behav Neurol. 1995;8(2): 115–119. doi: 10.3233/BEN-1995-8207 24487429

21. Jacobs DH, Shuren J, Bowers D, Heilman KM. Emotional facial imagery, perception and expression in Parkinson’s disease. Neurology. 1995;45(9): 1696–1702. doi: 10.1212/wnl.45.9.1696 7675229

22. Simons G, Ellgring H, Pasqualini MCS. Disturbance of spontaneous and posed facial expressions in Parkinson’s disease. Cogn Emot. 2003;17(5): 759–778.

23. Simons G, Pasqualini MC, Reddy V, Wood J. Emotional and non emotional facial expressions in people with Parkinson’s disease. J Int Neuropsychol Soc. 2004;10(4): 521–555. doi: 10.1017/S135561770410413X 15327731

24. Bowers D, Miller K, Bosch W, Gokcay D, Pedraza O, Springer U, et al. Faces of emotion in Parkinsons disease: micro-expressivity and bradykinesia during voluntary facial expressions. J Int Neuropsychol Soc. 2006;12(6): 765–773. doi: 10.1017/S135561770606111X 17064440

25. Miller KM, Okun MS, Marsiske M, Fennell EB, Bowers D. Startle reflex hyporeactivity in Parkinson’s disease: an emotion-specific or arousal-modulated deficit? Neuropsychologia. 2009;47(8): 1917–1927.

26. Smith MC, Smith MK, Ellgring H. Spontaneous and posed facial expression in Parkinson’s disease. J Int Neuropsychol Soc. 1996;2(5): 383–391. 9375163

27. Wieser MJ, Mühlberger A, Alpers GW, Macht M, Ellgring H, Pauli P. Emotion processing in Parkinson’s disease: dissociation between early neuronal processing and explicit ratings. Clin Neurophysiol. 2006;117(1): 94–102. doi: 10.1016/j.clinph.2005.09.009 16330254

28. Tracy JL, Robins RW. Putting the self into self-conscious emotions: A theoretical model. Psychol Inq. 2004;15(2): 103–125.

29. Nijhof G. Parkinson’s disease as a problem of shame in public appearance. Sociol Health Illn. 1995;17(2): 193–205.

30. Abudi S, Bar‐Tal Y, Ziv L, Fish M. Parkinson’s disease symptoms—‘patients’ perceptions. J Adv Nurs. 1997;25(1): 54–59. doi: 10.1046/j.1365-2648.1997.1997025054.x 9004011

31. Metzer WS. Severe essential tremor compared with Parkinson’s disease in male veterans: diagnostic characteristics, treatment, and psychosocial compli-cations. Southern Med J. 1992;85(8): 825–828. doi: 10.1097/00007611-199208000-00008 1502624

32. Khlebtovsky A, Rigbi A, Melamed E, Ziv I, Steiner I, Gad A, et al. Patient and caregiver perceptions of the social impact of advanced Parkinson’s disease and dyskinesias. J Neural Transm. 2012;119(11): 1367–1371. doi: 10.1007/s00702-012-0796-9 22437202

33. Spurgeon L, Clarke CE, Sackley C. Subjective experiences of speech and language therapy in patients with Parkinson’s disease: a pilot study. Rehabil Res Pract. 2015;839–895.

34. Balash Y, Korczyn AD, Knaani J, Migirov AA, Gurevich T. Quality‐of‐life perception by Parkinson’s disease patients and caregivers. Acta Neurol Scand. 2017;136(2): 151–154. doi: 10.1111/ane.12726 28083960

35. Schalling E, Johansson K, Hartelius L. Speech and communication changes reported by people with Parkinson’s disease. Folia Phoniatr Logop. 2017;69(3): 131–141. doi: 10.1159/000479927 29346787

36. Powell PA, Simpson J, Overton PG. Self-affirming trait kindness regulates disgust toward one’s physical appearance. Body Image. 2015;12:98–107. doi: 10.1016/j.bodyim.2014.10.006 25462888

37. Overton PG, Markland FE, Taggart HS, Bagshaw GL, Simpson J. Self-disgust mediates the relationship between dysfunctional cognitions and depressive symptomatology. Emotion. 2008;8(3): 379–385. doi: 10.1037/1528-3542.8.3.379 18540753

38. Powell PA, Simpson J, Overton PG.When disgust leads to dysphoria: three-wave longitudinal study assessing the temporal relationship between self-disgust and depressive symptoms. Cogn Emot. 2013;27(5): 900–913. doi: 10.1080/02699931.2013.767223 23410007

39. Azlan HA, Overton PG, Simpson J, Powell PA. Effect of partners’ disgust responses on psychological wellbeing in cancer patients. J Clin Psychol Med Settings. 2017;24(3–4): 355–364. doi: 10.1007/s10880-017-9521-z 29164511

40. Fox JR, Froom K. Eating disorders: A basic emotion perspective. Clin Psychol Psychother. 2009;16(4):328–35. doi: 10.1002/cpp.622 19639651

41. Olatunji BO, Cox R, Kim EH. Self-disgust mediates the associations between shame and symptoms of bulimia and obsessive-compulsive disorder. J Soc Clin Psychol. 2015;34(3): 239–258.

42. Ille R, Schöggl H, Kapfhammer HP, Arendasy M, Sommer M, Schienle A. Self-disgust in mental disorders—symptom-related or disorder-specific? Compr Psychiatry. 2014;55(4): 938–943. doi: 10.1016/j.comppsych.2013.12.020 24480418

43. Schrag A, Quinn N. Dyskinesias and motor fluctuations in Parkinson’s disease: A community-based study. Brain. 2000;123(11): 2297–2305.

44. Weintraub D, Mamikonyan E, Papay K, Shea JA, Xie SX, Siderowf A. Questionnaire for impulsive—compulsive disorders in Parkinson’s Disease–Rating Scale. Mov Disord. 2012;27(2): 242–247. doi: 10.1002/mds.24023 22134954

45. Timmer MHM, van Beek MHCT, Bloem BR, Esselink RAJ. What a neurologist should know about depression in Parkinson’s disease. Pract Neurol. 2017;17(5): 359–368. doi: 10.1136/practneurol-2017-001650 28739866

46. Schienle A, Wabnegger A, Schöngassner F, Leutgeb V. Effects of personal space intrusion in affective contexts: an fMRI investigation with women suffering from borderline personality disorder. Soc Cogn Affect Neurosci. 2015;10(10): 1424–1428. doi: 10.1093/scan/nsv034 25809402

47. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson’s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry. 1992, 55(3), 181–184. doi: 10.1136/jnnp.55.3.181 1564476

48. Goetz CG, Fahn S, Martinez-Martin P, Poewe W, Sampaio C, Stebbins GT, et al. Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS): Process, format, and clinimetric testing plan. Mov Disord. 2007;22(1): 41–47. doi: 10.1002/mds.21198 17115387

49. Goetz CG, Poewe W, Rascol O, Sampaio C, Stebbins GT, Counsell C, et al. Movement Disorder Society Task Force report on the Hoehn and Yahr staging scale: status and recommendations the Movement Disorder Society Task Force on rating scales for Parkinson’s disease. Mov Disord. 2004;19(9): 1020–1028.

50. Hoehn MM, Yahr MD. Parkinsonism: onset, progression and mortality. Neurology. 1967;17(5): 427–442. doi: 10.1212/wnl.17.5.427 6067254

51. Folstein MF, Folstein SE, McHugh PR. Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3): 189–98. doi: 10.1016/0022-3956(75)90026-6 1202204

52. Fountoulakis K. N., Tsolaki M., Chantzi H., & Kazis A. (2000). Mini mental state examination (MMSE): a validation study in Greece. Am J Alzheimers Dis Other Demen. 2000, 15(6), 342–345.

53. Bliwise DL, Trotti LM, Wilson AG, Greer SA, Wood‐Siverio C, Juncos JJ, et al. Daytime alertness in Parkinson’s disease: potentially dose‐dependent, divergent effects by drug class. Mov Disord. 2012;27(9): 1118–1124. doi: 10.1002/mds.25082 22753297

54. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr. Scand. 1983;67(6): 361–370. doi: 10.1111/j.1600-0447.1983.tb09716.x 6880820

55. Michopoulos I, Douzenis A, Kalkavoura C, Christodoulou C, Michalopoulou P, Kalemi G, et al. Hospital Anxiety and Depression Scale (HADS): validation in a Greek general hospital sample. Ann Gen Psychiatry. 2008;7(1): 1–5.

56. Patton JH, Stanford MS, Barratt ES. Factor structure of the Barratt Impulsiveness Scale. J. Clin. Psychol. 1995;51(6): 768–774. doi: 10.1002/1097-4679(199511)51:6<768::aid-jclp2270510607>3.0.co;2-1 8778124

57. Giotakos O, Markianos M, Vaidakis N, Christodoulou GN. Aggression, impulsivity, plasma sex hormones, and biogenic amine turnover in a forensic population of rapists. J Sex Marital Ther. 2003;29(3): 215–25. doi: 10.1080/00926230390155113 12851126

58. Tangney JP, Dearing RL, Wagner PE, Gramzow R. The Test of Self-Conscious Affect-3 (TOSCA-3). George Mason University: Fairfax; 2000.

59. Gouva M, Kaltsouda A, Paschou A. Psychometric Evaluation of the Greek version of TOSCA-3 to measure Shame and Guilt. Interscientific Health Care. 2012;4(3): 105–113.

60. Dickerson SS, Kemeny ME, Aziz N, Kim KH, Fahey JL. Immunological effects of induced shame and guilt. Psychosom Med. 2004;66(1): 124–131. doi: 10.1097/01.psy.0000097338.75454.29 14747646

61. Edgar KA, Skinner TC. Illness representations and coping as predictors of emotional well-being in adolescents with type 1 diabetes. J Pediatr Psychol. 2003;28(7): 485–493. doi: 10.1093/jpepsy/jsg039 12968040

62. Powell PA, Overton PG, Simpson J. The revolting self: Perspectives on the psychological, social, and clinical implications of self-directed disgust. London: Karnac books; 2014.

63. Kobayakawa M, Koyama S, Mimura M, Kawamura M. Decision making in Parkinson’s disease: Analysis of behavioral and physiological patterns in the Iowa gambling task. Mov Disord. 2008;23(4): 547–552. doi: 10.1002/mds.21865 18069681

64. Wylie SA, van den Wildenberg W, Ridderinkhof KR, Claassen DO, Wooten GF, Manning CA. Differential susceptibility to motor impulsivity among functional subtypes of Parkinson’s disease. J Neurol Neurosurg Psychiatry. 2012;83(12): 1149–1154. doi: 10.1136/jnnp-2012-303056 22917670

65. Obeso I, Wilkinson L, Casabona E, Bringas ML, Alvarez M, Alvarez L, et al. Deficits in inhibitory control and conflict resolution on cognitive and motor tasks in Parkinson’s disease. Exp Brain Res. 2011;212(3): 371–384. doi: 10.1007/s00221-011-2736-6 21643718

66. Giladi N, Weitzman N, Schreiber S, Shabtai H, Peretz C. New onset heightened interest or drive for gambling, shopping, eating or sexual activity in patients with Parkinson’s disease: The role of dopamine agonist treatment and age at motor symptom onset. J Psychopharmacol. 2007;21(5): 501–506. doi: 10.1177/0269881106073109 17446202

67. Weintraub D, Koester J, Potenza MN, Siderowf AD, Stacy M, Voon V, et al. Impulse control disorders in Parkinson’s disease: a cross-sectional study of 3,090 patients. Arch Neurol. 2010;67(5): 589–595. doi: 10.1001/archneurol.2010.65 20457959

68. Garlovsky JK, Simpson J, Grünewald RA, Overton PG. Impulse control disorders in Parkinson’s disease: Predominant role of psychological determinants. Psychol Health. 2016;31(12): 1391–1414. doi: 10.1080/08870446.2016.1218879 27473645

69. Grant JE, Levine L, Kim D, Potenza MN. Impulse control disorders in adult psychiatric inpatients. Am J Psychiatr. 2005;162(11): 2184–2188. doi: 10.1176/appi.ajp.162.11.2184 16263865

70. Evans AH, Strafella AP, Weintraub D, Stacy M. Impulsive and compulsive behaviors in Parkinson’s disease. Mov Disord. 2009;24(11): 1561–1570. doi: 10.1002/mds.22505 19526584

71. Pontone G, Williams JR, Bassett SS, Marsh L. Clinical features associated with impulse control disorders in Parkinson disease. Neurology. 2006;67(7): 1258–1261. doi: 10.1212/01.wnl.0000238401.76928.45 17030761

72. Sturm VE, Ascher EA, Miller BL, Levenson RW. Diminished self-conscious emotional responding in frontotemporal lobar degeneration patients. Emotion. 2008;8(6): 861–869. doi: 10.1037/a0013765 19102597

73. Parker ST. A social selection model for the evolution and adaptive significance of self-conscious emotions. In: Ferrari M, Sternberg RJ, editors. Self-awareness: Its nature and development. New York: Guilford Press; 1998. pp. 108–34.

74. Keltner D, Anderson C. Saving face for Darwin: The functions and uses of embarrassment. Curr Dir Psychol Sci. 2000;9(6): 187–192.

75. Robinson MD, Clore GL. Belief and feeling: evidence for an accessibility model of emotional self-report. Psychol Bull. 2002;128(6): 934. doi: 10.1037/0033-2909.128.6.934 12405138

76. Bieg M, Goetz T, Lipnevich AA. What students think they feel differs from what they really feel–academic self-concept moderates the discrepancy between students’ trait and state emotional self-reports. PLoS One. 2014;9(3): e92563. doi: 10.1371/journal.pone.0092563 24647760

77. Aftanas LI, Lotova NV, Koshkarov VI, Pokrovskaja VL, Popov SA, Makhnev VP. Non-linear analysis of emotion EEG: calculation of Kolmogorov entropy and the principal Lyapunov exponent. Neurosci Lett. 1997;226(1): 13–16. doi: 10.1016/s0304-3940(97)00232-2 9153630

78. Codispoti M, Ferrari V, Bradley MM. Repetitive picture processing: autonomic and cortical correlates. Brain Res. 2006;1068(1): 213–220. doi: 10.1016/j.brainres.2005.11.009 16403475

79. Lobbestael J, Arntz A, Wiers RW. How to push someone’s buttons: A comparison of four anger-induction methods. Cogn Emot. 2008;22(2): 353–373.

80. Tangney JP, Wagner P, Fletcher C, Gramzow R. Shamed into anger? The relation of shame and guilt to anger and self-reported aggression. J Pers Soc Psychol. 1992;62(4): 669–675. doi: 10.1037//0022-3514.62.4.669 1583590

81. Power MJ, Dalgleish T. Cognition and Emotion: From Order to Disorder (2nded.). East Sussex, England: Psychology Press; 2008.

82. Simpson J, Carter S, Anthony SH, Overton PG. Is disgust a homogeneous emotion? Motiv Emot. 2006;30(1): 31–41.

83. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999;56: 303. doi: 10.1001/archneur.56.3.303 10190820

84. Ready RE, Carvalho JO, Green RC, Gavett BE, Stern RA. The structure and validity of self-reported affect in mild cognitive impairment and mild Alzheimer’s disease. Int Psychogeriatr. 2011;23(6):887–98. doi: 10.1017/S104161021100041X 21429280

85. Waring JD, Dimsdale-Zucker HR, Flannery S, Budson AE, Kensinger EA. Effects of mild cognitive impairment on emotional scene memory. Neuropsychologia. 2017;96:240–8. doi: 10.1016/j.neuropsychologia.2017.01.011 28089697

86. Angiola JE, Bowen AM. Quality of life in advanced cancer: An acceptance and commitment therapy view. Couns Psychol. 2013;41(2): 313–335.

87. Ghielen I, van Wegen EE, Rutten S, de Goede CJ, Houniet-de Gier M, Collette E H, et al. Body awareness training in the treatment of wearing-off related anxiety in patients with Parkinson’s disease: Results from a pilot randomized controlled trial. J Psychosom Res. 2017;103: 1–8. doi: 10.1016/j.jpsychores.2017.09.008 29167034


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