Liver transplantation in patients with a history of migration—A German single center comparative analysis

Autoři: Julian Nikolaus Bucher aff001;  Maximilian Koenig aff001;  Markus Bo Schoenberg aff001;  Alexander Crispin aff002;  Michael Thomas aff001;  Martin Kurt Angele aff001;  Daniela Eser-Valeri aff003;  Alexander Lutz Gerbes aff004;  Jens Werner aff001;  Markus Otto Guba aff001
Působiště autorů: Department of General, Visceral and Transplant Surgery, Ludwig-Maximilians-University Munich, Munich, Germany aff001;  Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-University Munich, Munich, Germany aff002;  Department of Psychiatry, Ludwig-Maximilians-University Munich, Munich, Germany aff003;  Department of Medicine 2, Ludwig-Maximilians-University Munich, Munich, Germany aff004;  Transplantation Centre Munich, Ludwig-Maximilians-University Munich, Munich, Germany aff005;  Liver Centre Munich, Ludwig-Maximilians-University Munich, Munich, Germany aff006
Vyšlo v časopise: PLoS ONE 14(10)
Kategorie: Research Article


Liver transplant (LT) programs in Germany increasingly face a multiethnic patient population. To date no outcome data for LT in patients with a history of migration is available for Germany. This complicates decision-making before wait-listing such patients. We conducted a single-center cohort analysis of all primary LT between April 2007 and December 2015, stratified for the history of migration to investigate differences in the outcome. We found transplant rates resembling the proportion of persons with a history of migration in the general public in the region of our center. Differences were found concerning age at LT and prevalence of underlying diseases. Re-Transplant rates, Kaplan-Meier Estimates for overall survival, also after stratification for viral hepatitis, sex, ethnicity or presence of a language-barrier showed no statistical differences. The multivariate analysis showed no migration-related covariate associated with a negative outcome. These results stand in contrast to most of the previous evidence from North America and the UK and need to be taken into consideration during the wait-listing process of patients with a history of migration in need of a LT in centers in the Eurotransplant region.

Klíčová slova:

Cirrhosis – German people – Germany – Hepatitis B – Liver transplantation – Verbal communication – Autoimmune hepatitis – Hepatitis C


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2019 Číslo 10
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