The epidemiology of childhood intussusception in South Korea: An observational study


Autoři: Soyun Hwang aff001;  Joonghee Kim aff002;  Jae Yun Jung aff001;  Eun Mi Ham aff001;  Joong Wan Park aff001;  Hyuksool Kwon aff002;  Do Kyun Kim aff001;  Young Ho Kwak aff001
Působiště autorů: Department of Emergency Medicine, Seoul National University Hospital, Seoul, Republic of Korea aff001;  Department of Emergency Medicine, Seoul National University Bundang Hospital, Seongnan-si, Gyeonggi-do, Republic of Korea aff002
Vyšlo v časopise: PLoS ONE 14(12)
Kategorie: Research Article
doi: 10.1371/journal.pone.0219286

Souhrn

Intussusception is one of the most common causes of intestinal obstruction in young children. We report a retrospective, observational study of the epidemiology of intussusception in South Korea using the National Health Insurance Service-National Sample Cohort (NHIS-NSC). A cohort of newborns born between 2002 and 2008 was selected. The primary objective was to assess the incidence of intussusception in the pediatric population of Korea. The secondary objectives were to describe the basic epidemiological characteristics of intussusception and to identify risk factors. A total of 362 children were identified. The highest incidence of intussusception (2.6 per 1,000) was observed in children aged 1–2 years. A total of 58.8% of the children were male, and there was no significant difference in incidence according to the birth year (P = 0.804). Most of the children diagnosed with intussusception underwent air reduction, while only 0.6% had surgery. In all, 82.3% of the children were admitted to the hospital, 0.8% of them had to be admitted to the ICU, and the 6-month mortality was only 0.3%. In this retrospective, observational study, the incidence of intussusception was highest among children between 1 and 2 years of age. Most of the children underwent air reduction.

Klíčová slova:

Health insurance – Observational studies – Pediatrics – South Korea – Vaccination and immunization – Intussusception – Rotavirus – Pediatric epidemiology


Zdroje

1. Macdonald IA, Beattie TF. Intussusception presenting to a paediatric accident and emergency department. J Accid Emerg Med. 1995;12(3):182–6. Epub 1995/09/01. doi: 10.1136/emj.12.3.182 8581242; PubMed Central PMCID: PMC1342475.

2. Bines JE, Ivanoff B, Justice F, Mulholland K. Clinical case definition for the diagnosis of acute intussusception. J Pediatr Gastroenterol Nutr. 2004;39(5):511–8. Epub 2004/12/02. 15572891.

3. Jiang J, Jiang B, Parashar U, Nguyen T, Bines J, Patel MM. Childhood intussusception: a literature review. PLoS One. 2013;8(7):e68482. Epub 2013/07/31. doi: 10.1371/journal.pone.0068482 23894308; PubMed Central PMCID: PMC3718796.

4. Justice F, Carlin J, Bines J. Changing epidemiology of intussusception in Australia. J Paediatr Child Health. 2005;41(9–10):475–8. doi: 10.1111/j.1440-1754.2005.00686.x 16150062.

5. Palupi-Baroto R, Lee KJ, Carlin JB, Bines JE. Intussusception in Australia: epidemiology prior to the introduction of rotavirus vaccine. Aust N Z J Public Health. 2015;39(1):11–4. doi: 10.1111/1753-6405.12297 25558780.

6. Rosie B, Dalziel S, Wilson E, Best EJ. Epidemiology of intussusception in New Zealand pre-rotavirus vaccination. N Z Med J. 2016;129(1442):36–45. 27657157.

7. Jenke AC, Klaassen-Mielke R, Zilbauer M, Heininger U, Trampisch H, Wirth S. Intussusception: incidence and treatment-insights from the nationwide German surveillance. J Pediatr Gastroenterol Nutr. 2011;52(4):446–51. Epub 2011/03/19. doi: 10.1097/MPG.0b013e31820e1bec 21415671.

8. Van Trang N, Le Nguyen NT, Dao HT, Ho VL, Tran DT, Loewen J, et al. Incidence and Epidemiology of Intussusception among Infants in Ho Chi Minh City, Vietnam. J Pediatr. 2014;164(2):366–71. doi: 10.1016/j.jpeds.2013.10.006 24238857.

9. Cui P, Liu N, Li J, Huang T, Ge H, Wu Q, et al. [Epidemiology of intussusception related hospitalizations in children aged <2 years in Suzhou, 2007–2013]. Zhonghua Liu Xing Bing Xue Za Zhi. 2016;37(3):410–4. doi: 10.3760/cma.j.issn.0254-6450.2016.03.025 27005548.

10. Boudville IC, Phua KB, Quak SH, Lee BW, Han HH, Verstraeten T, et al. The epidemiology of paediatric intussusception in Singapore: 1997 to 2004. Ann Acad Med Singapore. 2006;35(10):674–9. 17102889.

11. Haber P, Patel M, Pan Y, Baggs J, Haber M, Museru O, et al. Intussusception after rotavirus vaccines reported to US VAERS, 2006–2012. Pediatrics. 2013;131(6):1042–9. Epub 2013/05/15. doi: 10.1542/peds.2012-2554 23669521.

12. Kim KY, Kim DS. Relationship between Pentavalent Rotavirus Vaccine and Intussusception: A Retrospective Study at a Single Center in Korea. Yonsei Med J. 2017;58(3):631–6. Epub 2017/03/24. doi: 10.3349/ymj.2017.58.3.631 28332371; PubMed Central PMCID: PMC5368151.

13. Lee J, Lee JS, Park SH, Shin SA, Kim K. Cohort Profile: The National Health Insurance Service-National Sample Cohort (NHIS-NSC), South Korea. Int J Epidemiol. 2017;46(2):e15. Epub 2016/01/30. doi: 10.1093/ije/dyv319 26822938.

14. Bines J, Ivanoff B. Acute Intussusception in Infants and Children: Incidence, Clinical Presentation and Management: A Global Perspective. Geneva, Switzerland: World Health Organization. 2002;Report 02.19.

15. Noguchi A, Nakagomi T, Kimura S, Takahashi Y, Matsuno K, Koizumi H, et al. Incidence of intussusception as studied from a hospital-based retrospective survey over a 10-year period (2001–2010) in Akita Prefecture, Japan. Jpn J Infect Dis. 2012;65(4):301–5. Epub 2012/07/21. 22814151.

16. Takeuchi M, Osamura T, Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S. Intussusception among Japanese children: an epidemiologic study using an administrative database. BMC Pediatr. 2012;12:36. Epub 2012/03/24. doi: 10.1186/1471-2431-12-36 22439793; PubMed Central PMCID: PMC3350444.

17. Jo DS, Nyambat B, Kim JS, Jang YT, Ng TL, Bock HL, et al. Population-based incidence and burden of childhood intussusception in Jeonbuk Province, South Korea. Int J Infect Dis. 2009;13(6):e383–8. Epub 2009/04/14. doi: 10.1016/j.ijid.2009.01.011 19362503.

18. Satter SM, Aliabadi N, Yen C, Gastanaduy PA, Ahmed M, Mamun A, et al. Epidemiology of childhood intussusception in Bangladesh: Findings from an active national hospital based surveillance system, 2012–2016. Vaccine. 2017. Epub 2017/09/25. doi: 10.1016/j.vaccine.2017.08.092 28941622.

19. Mehendale S, Kumar CP, Venkatasubramanian S, Prasanna T. Intussusception in Children Aged Less than Five years. Indian J Pediatr. 2016;83(10):1087–92. doi: 10.1007/s12098-016-2152-9 27211600.

20. Blanch AJ, Perel SB, Acworth JP. Paediatric intussusception: epidemiology and outcome. Emerg Med Australas. 2007;19(1):45–50. doi: 10.1111/j.1742-6723.2007.00923.x 17305660.

21. Gadisa A, Tadesse A, Hailemariam B. Patterns and Seasonal Variation of Intussusception in Children: A Retrospective Analysis of Cases Operated in a Tertiary Hospital in Ethiopia. Ethiop Med J. 2016;54(1):9–15. 27191025.

22. Bratton SL, Haberkern CM, Waldhausen JH, Sawin RS, Allison JW. Intussusception: hospital size and risk of surgery. Pediatrics. 2001;107(2):299–303. Epub 2001/02/07. doi: 10.1542/peds.107.2.299 11158462.

23. Desai R, Cortese MM, Meltzer MI, Shankar M, Tate JE, Yen C, et al. Potential intussusception risk versus benefits of rotavirus vaccination in the United States. Pediatr Infect Dis J. 2013;32(1):1–7. Epub 2012/08/30. doi: 10.1097/INF.0b013e318270362c 22929172.


Článek vyšel v časopise

PLOS One


2019 Číslo 12