On the interpretation of the atmospheric mechanism transporting the environmental trigger of Kawasaki Disease

Autoři: Joan Ballester aff001;  Sílvia Borràs aff001;  Roger Curcoll aff002;  Albert Navarro-Gallinad aff001;  Sofya Pozdniakova aff001;  Lidia Cañas aff001;  Jane C. Burns aff003;  Xavier Rodó aff001
Působiště autorů: Climate and Health Program (CLIMA), Barcelona Institute for Global Health (ISGlobal), Barcelona, Catalonia, Spain aff001;  Institute of Environmental Sciences and Technologies (ICTA), Autonomous University of Barcelona (UAB), Barcelona, Catalonia, Spain aff002;  Kawasaki Disease Research Center, University of California San Diego (UCSD), La Jolla, California, United States aff003;  Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Catalonia, Spain aff004
Vyšlo v časopise: PLoS ONE 14(12)
Kategorie: Formal Comment
doi: https://doi.org/10.1371/journal.pone.0226402


Recent advances on the environmental determinants of Kawasaki Disease have pointed to the important role of the atmospheric transport of a still unknown agent potentially triggering the disease. The hypothesis arose from an innovative methodology combining expertise in climate dynamics, the analysis of ocean and atmosphere data, the use of dispersion models and the search for biological agents in air samples. The approach offered a new perspective to reveal the identity of the potential trigger, but at the same time, it increased the level of complexity, which could potentially lead to the misinterpretation of the mechanisms. Some years after it was originally formulated, we here provide a brief clarification on the approach and limits of the methodology in order to prevent an eventual misuse of our research ideas and theory, so that further research can better focus on the knowledge gaps that still remain open.

Klíčová slova:

Atmospheric dynamics – Japan – Oceans – Pacific Ocean – Seasons – Spring – Winter – Kawasaki disease


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2019 Číslo 12
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