Survey on antimicrobial usage in local dairy cows in North-central Nigeria: Drivers for misuse and public health threats


Autoři: Nma Bida Alhaji aff001;  Mohammed Baba Aliyu aff001;  Ibrahim Ghali-Mohammed aff002;  Ismail Ayoade Odetokun aff002
Působiště autorů: Department of Public Health and Epidemiology, Niger State Ministry of Livestock and Fisheries, Minna, Nigeria aff001;  Department of Veterinary Public Health and Preventive Medicine, University of Ilorin, Ilorin, Nigeria aff002
Vyšlo v časopise: PLoS ONE 14(12)
Kategorie: Research Article
doi: 10.1371/journal.pone.0224949

Souhrn

Background

Antimicrobials are used as a measure to maintain good health and productivity of lactating cows. This study assessed pastoralists’ knowledge and practices regarding AMU in lactating cows; and risk pathways for AMR dissemination from cow milk to humans.

Methods

Interview questionnaire-based cross-sectional study was conducted in Fulani pastoral communities. Frequencies and proportions were used for descriptive statistics. Chi-square test and multivariable logistic regressions were used for analytic statistics at 95% confidence level.

Results

All recruited 384 pastoral households participated. About 11% of participants indicated antimicrobials misuse as when given at under-dose, while 58.9% had no knowledge of what antimicrobial misuse entailed. Most participants (51.6%) were unaware about effects of improper AMU. Most respondents (61.7%) reported self-prescription of antimicrobials used on cows. Also, 67.4% of respondents reported arbitrary applications of antimicrobials used in cows, while 15% used antimicrobials to increase milk yield. Frequently used antimicrobials were: tetracycline (98.7%), penicillin (96.6%), streptomycin (95.8%) and sulfonamides (95.3%). Consumption of raw milk and milk products (p = 0.010); contacts with contaminated udder (p = 0.002); and aerosols of discarded contaminated milk P = 0.001) were perceived risk pathways for spread of antimicrobial resistance from cow milk. Improper AMU (p<0.001), non-enforcement of regulating laws (p<0.001), weak financial status (p<0.001), and low education and expertise (p<0.001) influenced antimicrobials misuse in lactating cows.

Conclusions

This study highlighted low levels of knowledge, risk perceptions and practices regarding AMU and AMR among survey pastoralists. This calls for education of the vulnerable populations on promotion of prudent AMU in lactating cows through ‘One Health’ approach, to assure food safety, food security, and public and environmental health.

Klíčová slova:

Antimicrobial resistance – Antimicrobials – Bovine mastitis – Livestock – Mastitis – Milk – Nigeria – Public and occupational health


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Článek vyšel v časopise

PLOS One


2019 Číslo 12