Circulation of influenza virus from 2009 to 2018 in Cameroon: 10 years of surveillance data


Autoři: Richard Njouom aff001;  Chavely Gwladys Monamele aff001;  Hermann Landry Munshili Njifon aff001;  Sebastien Kenmoe aff001;  Mohamadou Ripa Njankouo aff001aff001
Působiště autorů: Virology Department, Centre Pasteur of Cameroon, Yaoundé, Cameroon aff001
Vyšlo v časopise: PLoS ONE 14(12)
Kategorie: Research Article
doi: 10.1371/journal.pone.0225793

Souhrn

Since the recent emergence of several subtypes of influenza viruses with pandemic potentials, there has been growing interest on the control of this infection worldwide. This study aimed to describe the 10 years of influenza activity in Cameroon between January 2009 and December 2018. Respiratory samples were collected from sentinel sites responsible for influenza surveillance in Cameroon and analyzed for the presence of influenza. Globally, 9 of the 10 administrative regions of the country were represented with at least 1 year of data. A total of 11816 respiratory samples were collected and influenza virus detection rate was 24.0%. The most represented age group was the 0–1 years representing more than 40% of the collected samples and possessing the lowest proportion of influenza cases (16.2%). Meanwhile higher proportions of influenza positive cases was found in the 2–4, 5–14 and 15–49 years age group at ≥29%. Among outpatients, the frequency of influenza virus was 24.8% while in hospitalized patients, 18.7% of samples were positive for influenza virus. We noted year-round circulation of influenza virus in Cameroon with 2 peaks in activity: a major peak in the months of September to December and a minor peak in the months of March to July. Antigenic characterization of influenza isolates showed 37.5% (6/16) vaccine match between the predominant Cameroon strains and the Northern hemisphere vaccine strains with majority of vaccine match observed in influenza B/Victoria subtype (4/6; 66.7%). Data collected from this surveillance system is essential to add to global information on the spread of influenza.

Klíčová slova:

Age groups – Cameroon – Infectious disease surveillance – Influenza – Influenza A virus – Influenza viruses – Vaccines – Viral vaccines


Zdroje

1. WHO. Influenza (Seasonal) Media centre: WHO; 2018. Available from: http://www.who.int/mediacentre/factsheets/fs211/en/.

2. Maman I, Badziklou K, Landoh ED, Halatoko AW, Nzussouo TN, Defang GN, et al. Implementation of influenza-like illness sentinel surveillance in Togo. BMC public health. 2014;14:981. doi: 10.1186/1471-2458-14-981 25239536

3. WHO. Influenza seasonality: timing and formulation of vaccines. Bulletin of the World Health Organization. 2014;92:311. doi: 10.2471/BLT.14.139428 24839317

4. Chadha MS, Broor S, Gunasekaran P, Potdar VA, Krishnan A, Chawla‐Sarkar M, et al. Multisite virological influenza surveillance in India: 2004–2008. Influenza and other respiratory viruses. 2012;6(3):196–203. doi: 10.1111/j.1750-2659.2011.00293.x 21955356

5. Njouom R, Mba SA, Noah DN, Gregory V, Collins P, Cappy P, et al. Circulation of human influenza viruses and emergence of Oseltamivir-resistant A(H1N1) viruses in Cameroon, Central Africa. BMC infectious diseases. 2010;10:56. doi: 10.1186/1471-2334-10-56 20205961

6. Njouom R, Yekwa EL, Cappy P, Vabret A, Boisier P, Rousset D. Viral etiology of influenza-like illnesses in Cameroon, January-December 2009. The Journal of infectious diseases. 2012;206 Suppl 1:S29–35.

7. Bonney JH, Kronmann KC, Lindan CP, Asante IA, Parbie P, Aboagye J, et al. Virological surveillance of influenza-like illness among children in Ghana, 2008–2010. The Journal of infectious diseases. 2012;206 Suppl 1:S108–13.

8. Dalhatu IT, Medina-Marino A, Olsen SJ, Hwang I, Gubio AB, Ekanem EE, et al. Influenza viruses in Nigeria, 2009–2010: results from the first 17 months of a national influenza sentinel surveillance system. The Journal of infectious diseases. 2012;206 Suppl 1:S121–8.

9. Nyatanyi T, Nkunda R, Rukelibuga J, Palekar R, Muhimpundu MA, Kabeja A, et al. Influenza sentinel surveillance in Rwanda, 2008–2010. The Journal of infectious diseases. 2012;206 Suppl 1:S74–9.

10. Lutwama JJ, Bakamutumaho B, Kayiwa JT, Chiiza R, Namagambo B, Katz MA, et al. Clinic- and hospital-based sentinel influenza surveillance, Uganda 2007–2010. The Journal of infectious diseases. 2012;206 Suppl 1:S87–93.

11. Manirakiza A, Ketta M-YB, Vickos U, Komoyo GF, Garba-ouangole S, Bangue C, et al. Sentinel surveillance of influenza-like illness in the Central African Republic, 2010–2015. Archives of Public Health. 2017;75(1):61.

12. Talla Nzussouo N, Duque J, Adedeji AA, Coulibaly D, Sow S, Tarnagda Z, et al. Epidemiology of influenza in West Africa after the 2009 influenza A(H1N1) pandemic, 2010–2012. BMC infectious diseases. 2017;17(1):745. doi: 10.1186/s12879-017-2839-1 29202715

13. Mainassara HB, Lagare A, Tempia S, Sidiki A, Issaka B, Abdou Sidikou B, et al. Influenza Sentinel Surveillance among Patients with Influenza-Like-Illness and Severe Acute Respiratory Illness within the Framework of the National Reference Laboratory, Niger, 2009–2013. PLoS One. 2015;10(7):e0133178. doi: 10.1371/journal.pone.0133178 26230666

14. Caini S, Andrade W, Badur S, Balmaseda A, Barakat A, Bella A, et al. Temporal Patterns of Influenza A and B in Tropical and Temperate Countries: What Are the Lessons for Influenza Vaccination? PLoS ONE. 2016;11(3):e0152310. doi: 10.1371/journal.pone.0152310 27031105

15. Monamele GC, Vernet MA, Nsaibirni RFJ, Bigna JJR, Kenmoe S, Njankouo MR, et al. Associations between meteorological parameters and influenza activity in a subtropical country: Case of five sentinel sites in Yaounde-Cameroon. PLoS One. 2017;12(10):e0186914. doi: 10.1371/journal.pone.0186914 29088290

16. Tamerius JD, Shaman J, Alonso WJ, Bloom-Feshbach K, Uejio CK, Comrie A, et al. Environmental Predictors of Seasonal Influenza Epidemics across Temperate and Tropical Climates. PLoS Pathog. 2013;9(3):e1003194. doi: 10.1371/journal.ppat.1003194 23505366

17. Chadsuthi S, Iamsirithaworn S, Triampo W, Modchang C. Modeling Seasonal Influenza Transmission and Its Association with Climate Factors in Thailand Using Time-Series and ARIMAX Analyses. Computational and mathematical methods in medicine. 2015;2015:436495. doi: 10.1155/2015/436495 26664492

18. Simmerman JM, Chittaganpitch M, Levy J, Chantra S, Maloney S, Uyeki T, et al. Incidence, Seasonality and Mortality Associated with Influenza Pneumonia in Thailand: 2005?2008. PLoS ONE. 2009;4(11):e7776. doi: 10.1371/journal.pone.0007776 19936224

19. Soebiyanto RP, Clara WA, Jara J, Balmaseda A, Lara J, Lopez Moya M, et al. Associations between seasonal influenza and meteorological parameters in Costa Rica, Honduras and Nicaragua. Geospatial health. 2015;10(2):372. doi: 10.4081/gh.2015.372 26618318

20. WHO. Influenza (Seasonal) Mediacentre: WHO; 2016 [January 2017]. Available from: http://www.who.int/mediacentre/factsheets/fs211/en/.


Článek vyšel v časopise

PLOS One


2019 Číslo 12