Effect of arteriovenous access closure and timing on kidney function in kidney transplant recipients

Autoři: Seonjeong Jeong aff001;  Hyunwook Kwon aff001;  Jee Yeon Kim aff001;  Young Hoon Kim aff001;  Tae-Won Kwon aff001;  Jung Bok Lee aff002;  Yong-Pil Cho aff001;  Duck Jong Han aff001
Působiště autorů: Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea aff001;  Department of Clinical Epidemiology and Biostatistics, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea aff002
Vyšlo v časopise: PLoS ONE 14(12)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0226309


This study aimed to determine whether the closure of a functioning arteriovenous (AV) access affects the estimated glomerular filtration rate (eGFR) and to compare outcomes according to the timing of AV access closure after kidney transplantation (KT). From 2009 to 2015, medical records were retrospectively reviewed for 142 kidney transplant recipients (KTRs) who underwent AV access closure. The 142 KTRs were categorized into three groups: AV access closure was performed within 6 months after KT in Group 1 (n = 45), at 6–12 months after KT in Group 2 (n = 49), and at 12–24 months after KT in Group 3 (n = 48). The baseline (at the time of AV access closure) and follow-up eGFR values during the 3-year follow-up period were compared. Linear mixed model analysis revealed no significant association between longitudinally observed eGFR values and the amount of time elapsed after AV access closure in the study population (P = 0.36). There was no significant association between 3-year eGFR values and the timing of AV access closure (P = 0.58). In conclusion, after successful KT, AV access closure did not affect the eGFR significantly, and the timing of AV access closure was not significantly associated with outcomes.

Klíčová slova:

Blood pressure – Creatinine – Glomerular filtration rate – Heart failure – Chronic kidney disease – Kidneys – Medical dialysis – Renal transplantation


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2019 Číslo 12
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