Drug-related and psychopathological symptoms in HIV-positive men who have sex with men who inject drugs during sex (slamsex): Data from the U-SEX GESIDA 9416 Study

Autoři: Helen Dolengevich-Segal aff001;  Alicia Gonzalez-Baeza aff003;  Jorge Valencia aff004;  Eulalia Valencia-Ortega aff003;  Alfonso Cabello aff005;  Maria Jesus Tellez-Molina aff006;  Maria Jesus Perez-Elias aff007;  Regino Serrano aff002;  Leire Perez-Latorre aff009;  Luz Martin-Carbonero aff003;  Sari Arponen aff010;  Jose Sanz-Moreno aff011;  Sara De la Fuente aff012;  Otilia Bisbal aff013;  Ignacio Santos aff014;  Jose Luis Casado aff007;  Jesus Troya aff015;  Miguel Cervero-Jimenez aff016;  Sara Nistal aff017;  Guillermo Cuevas aff015;  Javier Correas-Lauffer aff001;  Marta Torrens aff018;  Pablo Ryan aff015
Působiště autorů: Psychiatry Service, Henares University Hospital, Madrid, Spain aff001;  Faculty of Medicine, Universidad Francisco de Vitoria, Madrid, Spain aff002;  HIV Unit, La Paz University Hospital, IdiPAZ, Madrid, Spain aff003;  Harm Reduction Unit, SERMAS, Madrid, Spain aff004;  Infectious Diseases and HIV Unit, Fundación Jimenez Díaz, Madrid, Spain aff005;  HIV Unit, Clínico San Carlos University Hospital, Madrid, Spain aff006;  Infectious Diseases, Ramón y Cajal University Hospital, Madrid, Spain aff007;  HIV Unit, Henares University Hospital, Madrid, Spain aff008;  HIV Unit, Gregorio Marañón University Hospital, Madrid, Spain aff009;  Internal Medicine Service, Torrejon Hospital, Madrid, Spain aff010;  Internal Medicine, Príncipe de Asturias Hospital, Alcala de Henares, Spain aff011;  Internal Medicine Service, Puerta de Hierro Hospital, Madrid, Spain aff012;  HIV Unit, 12 de Octubre University Hospital, Madrid, Spain aff013;  Infectious Diseases Unit, La Princesa University Hospital, Madrid, Spain aff014;  Internal Medicine Service, Infanta Leonor Hospital, Madrid, Spain aff015;  Internal Medicine Service, Severo Ochoa Hospital, Madrid, Spain aff016;  Internal Medicine Service, Mostoles University Hospital, Madrid, Spain aff017;  Institut de Neuropsiquiatria i Addiccions, Hospital del Mar, Barcelona, Spain aff018;  School of Medicine, Complutense University, Madrid, Spain aff019;  Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain aff020
Vyšlo v časopise: PLoS ONE 14(12)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0220272



Sexualized intravenous drug use, also known as slamsex, seems to be increasing among HIV-positive men who have sex with men (MSM). Physical and psychopathological symptoms have previously been reported in this population, although research on the subject of slamsex is scarce. The objectives of our study were to describe the psychopathological background of a sample of HIV-positive MSM who engaged in slamsex during the previous year and to compare physical, psychopathological, and drug-related symptoms between these participants and those who engaged in non-injecting sexualized drug use.

Design and methods

Participants (HIV-positive MSM) were recruited from the U-Sex study in 22 HIV clinics in Madrid during 2016–17. All participants completed an anonymous cross-sectional online survey on sexual behavior and recreational drug use. When participants met the inclusion criteria, physicians offered them the opportunity to participate and gave them a card with a unique code and a link to access the online survey. The present analysis is based on HIV-positive MSM who had engaged in slamsex and non-injecting sexualized drug use.


The survey sample comprised 742 participants. Of all the participants who completed the survey, 216 (29.1%) had engaged in chemsex, and of these, 34 (15.7%) had engaged in slamsex. Participants who engaged in slamsex were more likely to have current psychopathology (depression, anxiety, and drug-related disorders) than participants who engaged in non-injecting sexualized drug use. In addition, participants who engaged in slamsex more frequently reported high-risk sexual behaviors and polydrug use and were more often diagnosed with sexually transmitted infections (STIs) and hepatitis C than those who did not inject drugs. Compared with participants who did not inject drugs, participants who engaged in slamsex experienced more severe drug-related symptoms (withdrawal and dependence), symptoms of severe intoxication (loss of consciousness), and severe psychopathological symptoms during or after slamsex (eg, paranoid thoughts and suicidal behaviors).


Slamsex is closely associated with current psychiatric disorders and severe drug-related and psychiatric symptoms.

Klíčová slova:

Consciousness – Depression – Drug addiction – Drug dependence – Men who have sex with men – Suicide – Syncope – Sex addiction


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