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ReklamaUse of IoT sensing and occupant surveys for determining the resilience of buildings to forest fire generated PM2.5
Authors: Jovan Pantelic aff001; Megan Dawe aff001; Dusan Licina aff002
Authors place of work: Center for the Built Environment, University of California, Berkeley, California, United States of America aff001; Human-Oriented Built Environment Lab, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland aff002
Published in the journal: PLoS ONE 14(10)
Category: Research Article
doi: https://doi.org/10.1371/journal.pone.0223136Summary
Wildfires and associated emissions of particulate matter pose significant environmental and health concerns. In this study we propose tools to evaluate building resilience to extreme episodes of outdoor particulate matter using a combination of indoor and outdoor IoT measurements, coupled with survey-based information of occupants’ perception and behaviour. We demonstrated the application of the tools on two buildings with different modes of ventilation during the Chico Camp fire event. We characterized the resilience of the buildings on different temporal and spatial scales using the well-established I/O ratio and a newly proposed E-index that evaluates indoor concentration in the context of adopted 24-hour exposure thresholds. Indoor PM2.5 concentration during the entire Chico Camp Fire event was 21 μg/m3 for 4th Street (Mechanically Ventilated) and 36 μg/m3 for Wurster Hall (Naturally Ventilated). The cumulative median I/O ratio during the fire event was 0.27 for 4th Street and 0.67 for Wurster Hall. Overall E-index for 4th Street was 0.82, suggesting that the whole building was resilient to outdoor air pollution while overall E-index was 1.69 for Wurster Hall suggesting that interventions are necessary. The survey revealed that occupant perception of workplace air quality aligns with measured PM2.5 in the two buildings. The results also highlight that a large portion of occupants wore face masks, even though the PM2.5 concentration was below WHO threshold level. The results of our study demonstrate the utility of the proposed IoT-enabled and survey tools to assess the degree of protection from air pollution of outdoor origin for a single building or across a portfolio of buildings. The proposed survey tool also provides direct links between the PM2.5 levels and occupants’ perception and behavior.
Keywords:
Surveys – Pollution – Carbon dioxide – Air pollution – Network resilience – Wildfires – Pollutants – Air quality
1. Introduction
In recent years, we have observed increased wildfire frequency and intensity in response to global warming [1]. Many regions prone to fire are forecasted to have increased frequency of wildfires and associated air pollution episodes [2]. Wildfire smoke includes carbon dioxide, water vapor, carbon monoxide, particulate matter (PM), complex hydrocarbons, nitrogen oxides, trace minerals, and several thousand other compounds [3]. There is clear evidence that wildfire smoke, which includes particulate matter with 2.5 μm diameter (PM2.5), is linked to respiratory health implications, morbidity, and mortality [4,5]. In the U.S., mathematical models show that premature deaths attributed to wildfire generated PM2.5 exposure will double compared to the early 21st century [6]. Furthermore, studies have shown that wildfire smoke exposure during pregnancy affected birth weight among term infants [7], and that mental health symptoms increased among an adolescent population exposed to wildfire smoke [8]. In planning for the future, cities, communities, and building ecosystems in wildfire prone regions need to be resilient to the associated wildfire effects [9], and provide safe indoor air quality (IAQ) to protect occupants.
In order to achieve appropriate IAQ, the building industry must develop standards for protecting building occupants against wildfire air pollution, which do not currently exist [10,11]. Building ventilation standards such as ASHRAE 62.1 and 62.2 only deal with typical outdoor air conditions (i.e., not under extreme air pollution events). The available guidelines include the British Columbia Center for Disease Control Wildfire Smoke Response Planning document that states: “More than one portable air cleaning unit may be required for large rooms or homes with high air change rates”. WHO/UNEP/WMO Guidelines for Vegetation fire events provide general recommendations, such as “reduce infiltration” or install and maintain “effective filters” [12]. The California Department of Health [13] provide similar guidance. WHO and EPA provide short-term (24-hr average) and long-term (annual) PM2.5 exposure thresholds, above which there are long-term human health impacts. The existing guidelines are largely qualitative without quantifiable instructions, such as an appropriate filter grade, air pollution monitoring and ventilation operation. Few studies have examined personal particle exposure indoors during air pollution events [14,15]. A study by [16] is one of the few that examined infiltration of wildfire generated air pollution into buildings. A major barrier to establishing standards and protecting occupants is that very few (if any) buildings have equipment to measure indoor PM or pollutants, besides CO2 and CO.
Internet of Things (IoT) environmental sensing platforms can be placed indoors and outdoors to measure diverse air pollutants, including PM2.5. IoT PM2.5 measurements can be used to understand the relationship between outdoor and indoor PM2.5 levels and pathways by which outdoor particles enter indoors. These relationships can be described with known metrics such as Indoor to Outdoor (I/O) ratio, infiltration factor (Fin), and penetration factor (P) [17]. The studies have concluded that low-cost IoT PM2.5 sensors have reasonable accuracy for building scale implementation [18,19,20] and that they are sufficiently accurate for identifying high air pollutant concentrations, as is observed in wildfires [21].
The effect of wildfire generated air pollution on human health and mortality highlight the importance of managing exposure. However, the barriers to reducing indoor exposure are three-fold. First, there are no quantifiable guidelines or standards in place. Second, there is a lack of measurement equipment in buildings for wildfire generated air pollutants, such as PM2.5. Lastly, without measurement equipment, the building industry is left with only the existing qualitative guidelines without the ability to quantify the effectiveness of resiliency strategies. This all leads to a significant gap in defining and quantifying building resiliency, effectiveness of chosen interventions, and general understanding of occupant exposure indoors. The objective of this study was to address the second two barriers by demonstrating how a combination of an IoT environmental sensing network implemented locally outdoors and inside the building and an occupant survey can quantify building resiliency to urban scale air pollution. In doing this, we applied known analytical tools and developed another. Specifically, we analyzed PM2.5 measurements during a wildfire event at different spatial (whole building or room scale) and temporal scales (instantaneous and long term) to demonstrate the application of building assessment tools. We used two buildings located in Berkeley (California) during the two-week Chico Camp fire in November 2018; one building was equipped with mechanical ventilation and the other with natural ventilation. By reliance on combination of I/O ratio metric, survey questionnaires and a newly proposed E-index, the study sought to quantify the resilience of buildings against particle penetration indoors from outdoor origin.
2. Materials and methods
We used two types of indoor PM2.5 sensors (Clarity Inc, and Senseware), one type of outdoor PM2.5 sensor (Clarity Inc), and one type of CO2 sensor (Senseware) placed on and in two commercial buildings in Berkeley, CA. One of the buildings was naturally ventilated, while the other was mechanically ventilated. We also developed and distributed a survey to gather feedback on occupant experience in their workplace during the Chico Camp fire compared to their typical experience in the space. With this data, we developed and evaluated tools to quantify and assess each building’s resilience to the extreme air pollution episode.
2.1 Experimental apparatus
Both Clarity and Senseware PM2.5 nodes (Fig 1) count the particle number using the principle of light scattering, which are characteristic for optical particle counters. The accuracy of the all the sensors was the same—within ±10 μg/m3 in the range of 0 to 100 μg/m3 and ±10% in the range of 100 to 1000 μg/m3. Data was collected on 15-minute intervals for Clarity nodes on 1-minute intervals for Senseware nodes. As typical for optical particle counters, Clarity and Senseware nodes are factory-calibrated with Arizona Test Dust (ATD). Calibration with ATD does not robustly account for many aerosol particle properties, such as density, shape, refractive index, and absorption. Therefore, if aerosol properties of the particles measured in the field do not have properties similar to ATD (as is likely the case for wildfires), the optical particle counters can produce inaccurate readings. There is a lack of understanding of the wildfire source profiles and resulting aerosol composition [22]; thus making the field calibration challenging. To arrive at accurate measurements, the Clarity nodes apply co-location of nodes and post-processing correction factors to the raw outdoor measurements using a local government measurement stations that indirectly include information on particle optical properties. For this dataset, the Clarity node corrections for particle optical properties were extracted from the California Air Resources Board Oakland Laney College measurement station. Clarity Inc. typically only applies these corrections to outdoor nodes; however, we applied the same correction to indoor Clarity nodes because under the Chico Camp fire scenario indoor PM2.5 dominantly originated from the outdoors. Senseware nodes do not make corrections to the raw measurements and are calibrated with the ATD.
Fig. 1. IoT sensors used in the study: Clarity outdoor node (right); Clarity indoor note (middle); Senseware indoor node (left). Senseware CO2 sensors measured CO2 levels with an accuracy of ±50 ppm. In Wurster Hall, the CO2 sensors were paired with PM2.5 measurements, while in 4th Street they were placed in two representative locations. Senseware contact monitors—(Model COZIR-LP) were mounted on the windows in Wurster Hall to detect window position. Detection was binary (i.e., open/closed) and did not provide information on opening area or window angle.
2.2 Quality assurance
Prior to deployment, Clarity Inc. and Senseware PM2.5 nodes were compared side-by-side and with Grimm aerosol spectrometer (model 11-A, GRIMM Aerosol Technik GmbH, Ainring, Germany) that provides time-and size-resolved data for aerosol particles. Clarity and Senseware PM2.5 nodes were within ±8 μg/m3 compared to Grimm measurements at ambient PM2.5 levels ranging from 10 μg/m3 to 45 μg/m3, which is within the given accuracy for each node.
2.3 Experimental design
We selected two buildings, 1608 4th Street Building (mechanically ventilated) and Wurster Hall (mixed-mode ventilation operating as fully naturally ventilated during the study period) to deploy sensors. Both buildings were located in Berkeley (California). In March 2018, we deployed indoor and outdoor PM2.5 sensors, indoor CO2 sensors in both buildings and window contact sensors in Wurster Hall. Berkeley was affected by air pollution from the Chico Camp fire from November 8th until November 21st, 2018. The current study provides analysis of data collected during the Chico Camp fire.
1608 4th Street Building (abbreviated as 4th Street) is a mechanically ventilated building with centralized heating, ventilation and air-conditioning (HVAC) system. The HVAC system utilizes three stages of air filtration: the first stage of filtration is by a MERV 8 pleated filter, the second stage is the Gas Phase filter, and the final filter stage is a high-efficiency MERV 13 filter. The measure CO2 decay profile during non-occupied hours were used to calculate infiltration rates (details in the Supporting Information). Infiltration was below 0.3 air exchanges per hour suggesting that the building is airtight without operable windows. The building has approximately 270 full-time occupants.
Wurster Hall—Mixed-mode building with seasonal changeover, meaning that the building is fully naturally ventilated when the building is operating in cooling, as was the case during the Chico Camp fire. The building relies on operable windows for ventilation and cooling. The building has a high level of infiltration, as shown by typical CO2 levels below 550 ppm during normal operation. The building has approximately 300 full-time occupants.
2.3.1 Placement of outdoor and indoor sensors
1608 4th Street Building—is occupied on the 2nd, 3rd and 4th floor. Floors had the same layouts; therefore, considering the available number of sensors, we placed all sensors on the 3rd floor. We placed one outdoor PM2.5 sensor (Clarity node) on the roof of the building, and 15 PM2.5 sensors (14 Senseware nodes and one Clarity node) at different indoor locations. S1 Fig in the Supporting Information provides a floor plan with sensor locations in the 4th Street. Each of the floors consists of large open floor office area with high partitions housing 71 stations, six private offices, two team meeting rooms, one large team meeting room, and two phone booths. We placed one PM2.5 and one CO2 sensor in the private office, and the remaining sensors in the open floor office. We wanted to measure if the building envelope was leaky, so we placed PM2.5 sensors near outside walls with windows so that we can conservatively estimate building operation.
Wurster Hall—consisted of two building wings with separate HVAC systems. The south wing is four stories and consisted of classrooms, open plan offices, small and large meeting rooms, and several private offices. The north wing is 10 stories and consisted almost entirely of large open plan offices. Our study focused on the south wing of the building. We placed one PM2.5 sensor (Clarity node) on the roof above the 4th floor, and 11 PM2.5 sensors (10 Senseware nodes and one Clarity node). Private offices were the most common space type in Wurster Hall’s south wing; therefore, we placed the majority of PM2.5 and CO2 sensors in that environment. Additionally, we placed sensors in one meeting room with operable windows and in one small open plan office with four occupants. This particular open plan office was chosen also because it was adjacent to the hallway with an entrance door to the building. S2 Fig in the Supporting Information provides a floor plan with sensor locations in the Wurster Hall. We placed contact sensors on operable windows; each room had at least one manually operated awning-type window, and some rooms had two or more depending on the size of the space.
2.4 Data analysis
An assumption for data analysis was that the dominant source of indoor PM2.5 originated from the outdoors. Although this assumption is not generally valid at typical outdoor PM2.5 concentrations, in this case, the PM2.5 data collected before and after the Chico Camp Fire showed typical indoor PM2.5 concentrations below 3 μg/m3, implying that indoor sources were not significant relative to the outdoor PM2.5 during forest fires. The average indoor raw PM2.5 concentrations (i.e., not corrected for particle properties) measured in each building during the Chico Camp fire followed trends of outdoor measurements and were approximately 80 times greater than the average concentrations measured the week before and after the Chico Camp fire. This validates the assumption that all indoor particles can be treated as having outdoor origin during the Chico Camp fire.
As mentioned, Clarity Inc. corrects measured data to include information about PM2.5 composition, while Senseware measurements rely on ATD calibration. Due to this disparity, the analysis uses raw measurements when combining or comparing data from the Clarity and Senseware nodes, and the Clarity corrected measurements when discussing observed indoor and outdoor PM2.5 concentrations. For the analysis, we define building operating hours as 07 : 00 to 19 : 00. When presenting the results, we identify the median value with the interquartile range in parentheses (i.e., the range between the 25th and 75th percentiles), for example median PM2.5 concentration of 21 μg/m3 (IQR = 13 μg/m3).
2.4.1 Outdoor PM2.5 comparison
We compared local (i.e., building) outdoor PM2.5 concentrations to nearby regional weather station measurements to evaluate the current assumption that regional measurements are representative of individual exposure.
2.4.2 Building assessment tools
We assessed the following tools for characterizing building resiliency during extreme pollution events based on IoT environmental sensing:
- (i)
Comparison of indoor PM2.5 concentrations to the WHO exposure threshold value for PM2.5. We chose the WHO guidelines because it is the strictest, with the maximum 24-hour mean exposure of 25 μg/m3. Alternative guidelines such as EPA may be used, depending on the region of the world. We compared median hourly indoor PM2.5 concentration (i.e., median value from all indoor sensors) to WHO 24-hour mean exposure guideline, and calculated the Exceedance index (E-index), as shown in Eq 1, on an hourly basis. The E-index, is a unitless value that informs by how much hourly PM2.5 concentration exceeds the recommended level. We can then calculate the number or percent of hours that indoor PM2.5 concentration exceeded specified levels during the air pollution episode, or the whole building average E-index. It is a tool to evaluate occupant exposure that can be compared across buildings during extreme air pollution events. This can also be done on a space-by-space basis within the same building.
- (ii)
Comparison of indoor and outdoor PM2.5 concentrations. Outdoor PM2.5 can enter the indoor environment mainly by penetration (uncontrolled via building cracks and doors) or ingress (controlled via mechanical ventilation system or windows). From the building operation perspective, quantification of pathways and the quantity of outdoor particles that enter the indoor environment is one of the most important aspects of building resilience to extreme air pollution events. Considering negligible indoor PM2.5 sources, we quantified PM2.5 penetration using indoor to outdoor particle (I/O) ratio (Eq 2) using outdoor and indoor PM2.5 measurements. Eq 2 is appropriate when the indoor pollution sources can be neglected, as we determined is the case for this event. We can calculate I/O ratio at different temporal (i.e., cumulative episode or hourly) and spatial (i.e., whole building or by room) scales, which informs different scenarios of interest. The differences between I/O ratios among nearby buildings is typically attributed to differences in indoor particle sources, geometry of building cracks, wind direction and intensity, ventilation strategy and rate, and air filtration (16). We supplemented the I/O ratio analysis with information on infiltration rates calculated using CO2 decay and knowledge of the HVAC system operation.
Instantaneous I/O ratio was calculated for each indoor sensor location using hourly mean indoor and outdoor PM2.5 concentration (Eq 2, where Cin(t) and Cout(t) are the hourly means). We defined instantaneous as hourly in this study, but the calculation could be done at smaller time steps if necessary for a building or space. We used raw measurements from all sensors so data was comparable between sensor manufacturer. To calculate the whole building Instantaneous I/O ratio, we used the median hourly mean PM2.5 from the indoor sensors compared to the hourly mean outdoor PM2.5 concentration; we used the median value instead of the mean because it is robust to outlier instances, such as a window being left open which occurred in one space. Instantaneous I/O ratio is a tool that enables quick-response comparison between buildings and between spaces within a building on a short time scale.
Cumulative I/O ratio was calculated for each building to represent the overall whole building I/O ratio over a given period of time post-event, which was the Chico Camp fire period for this study. It is the median value of all the mean hourly I/O ratios at each sensor location in a building during an event. While the Instantaneous I/O ratios can vary depending on environmental conditions and driving forces (e.g. air temperatures and outdoor wind speeds), the Cumulative I/O ratio provides an overall value to compare buildings’ abilities to prevent infiltration and penetration of outdoor pollutants during extreme pollution events. The Cumulative I/O ratio can also be calculated at each sensor location to compare between spaces within a building.
2.4.3 Survey of occupants
It may not always be feasible to measure indoor and outdoor PM2.5 for every building due to sensor availability and cost. A survey is an economical and simple method to gather data; however, it relies on self-reported information from occupants which may not always reflect the environmental conditions. This study compares the indoor PM2.5 measurements with occupant feedback on perceived air quality, impacts to productivity from air quality, and behavior changes during the Chico Camp fire compared to their typical experience in the space. We then evaluated the potential effectiveness of surveys as a building assessment tool.
The voluntary web-based survey was distributed to full-time occupants in each building between March 13 and March 22, 2019. University of California at Berkeley Institutional Review Board specifically approved this study (obtained Protocol ID:2019-02-11802). Although there is a four-month gap between the fire and occupants’ survey responses, the intensity of air pollution during the Chico Camp fire was atypical enough for the Berkeley area that we think the responses are valid representations of occupants’ perception and behavior during that time. The survey used a five-point scale from -2 to +2 to rate occupant satisfaction from “dissatisfied” to “satisfied” or”interfered” to”enhanced”, with a neutral vote as the middle value. The survey had two parts: first, the occupants were asked about their typical experience in the space, and then secondly, about their experiences during the Chico Camp fire. The survey main topics and rating scale included items listed in Table 1, and survey questions can be found in Supplemental information (Wildfire air quality survey).
Tab. 1. Surveyed topics and response scales provided to survey respondents. Campus closures occurred on Nov 16, 19, and 20 in response to outdoor pollutant levels, with the exception of some services that included staff in 4th Street; therefore, many 4th Street occupants worked in their building during the closure while Wurster Hall was closed. The survey controlled for and separated out these days to understand whether occupants in either building worked in their workplace on those days.
2.5 Statistical tools used
We analyzed the IoT sensing and survey data using R version 3.5.0 software [23]. We performed statistical analysis on the measured sensor data to compare between sensor locations (i.e., between buildings, between buildings and a regional weather station, and within buildings) and to compare survey responses between buildings and between typical conditions (i.e., non-forest fire) and forest fire responses. The data under consideration was not normally distributed, so we used non-parametric tests. To assess statistical significance between measured PM2.5 concentrations at different locations, we used a two-sided Wilcoxon Rank-Sum test, also known as Mann-Whitney test. To compare IAQ satisfaction survey responses between buildings, we also used a two-sided Wilcoxon Rank-Sum test. We could have used a one-sided test because the hypothesis is that occupants in Wurster Hall had lower satisfaction than those in 4th Street, but we used a more conservative test. We tested all scenarios to a 95% confidence level, meaning statistical significance was considered when the p value was below 0.05. There is no guidance for effect size specific to occupant survey responses; we used Cohen’s d value and effect size recommended thresholds from [24] and [25].
3. Results and discussion
3.1 Outdoor PM2.5 results: Spatial variability
Results in Fig 2 shows (a) hourly mean and (b) cumulative outdoor PM2.5 concentration during the Chico Camp Fire for the two study buildings and four CARB PM2.5 measurement stations located within 24 km from the study buildings: Aquatic Park, Laney College, West Oakland and Oakland International Blvd. The results show that concentration peaks and median mass concentrations for 4th Street and Wurster Hall are different. Analysis of the results in Fig 2B shows that median outdoor levels between the two study sites differ by 17 μg/m3, even though the two locations were ~3.5 km away. Based on Wilcoxon Signed-Rank test, the difference between mean outdoor PM2.5 measurements for the two buildings is statistically significant (p<0.05), the difference in means between Wurster Hall and Laney College station is statistically significant (p<0.05), but the difference in means between 4th Street and Laney College station is not (p = 0.11). Laney College station was chosen as a reference because it was the closest weather station and was used in the Clarity Inc. sensor calibration. Results point out the importance of local sensing, and that any method to evaluate building resilience with respect to the outdoor PM2.5 levels needs to use local measurements.
Fig. 2. Hourly averaged outdoor PM measurements for the two study sites, and CARB aquatic park (closes to both sites), Laney College, West Oakland and International Blvd: a) hourly PM2.5 concentrations; b) cumulative box plot that includes the 25th percentile, median, and 75th percentile, and the whiskers represent the 5th and 95th percentiles. 3.2 Indoor PM2.5 results
Results in this section include (i) indoor PM2.5 concentrations and (ii) I/O ratio. In order to appropriately inform conclusions about the buildings from I/O ratios, we referenced information about the building infiltration and HVAC system operating hours to understand the underlying mechanisms that contributed to particle penetration and ingress.
3.2.1 Comparison of PM2.5 concentration to WHO guidance
We evaluated measured indoor PM2.5 concentrations to assess building resilience from the occupant exposure perspective because it affects occupant health, productivity, and comfort. Results in Fig 3 show that the median hourly indoor PM2.5 concentration over the entire Chico Camp Fire event was 21 μg/m3 (IQR = 13 μg/m3) for 4th Street and 36 μg/m3 (IQR = 29 μg/m3) for Wurster Hall. Theses values represent a general overview of the whole building indoor levels, which indicates that there was a difference in exposure levels between the two buildings. The overall whole building indoor PM2.5 levels provide a coarse indicator of IAQ when they are benchmarked against recommended thresholds, such as WHO 24 hr exposure limit of 25 μg/m3 or EPA limit of 35 μg/m3. Based on this simple comparison, we conclude that 4th Street is more resilient than Wurster Hall to the extreme air pollution event. This cumulative comparison is possible only after the air pollution event has occurred and is useful for ranking buildings across a large portfolio (e.g. campus, district, town) and identifying which buildings should have resource priority.
Fig. 3. Comparison of hourly PM2.5 concentrations between the two sites for the entire period of air pollution episode. The box plot represents the 25th percentile, median, and 75th percentile, and the whiskers represent the 5th and 95th percentiles. From the occupants’ perspective, PM2.5 concentration and amount of time they were exposed play a critical role in health implications. In order to evaluate this in the context of building resilience, we must simultaneously evaluate ambient concentration and exposure time, which is done with the developed E-index tool. In Fig 4, the x-axis represents days during the pollution episode, the y-axis represents hour of the day, with horizontal dotted lines indicating typical building operation hours of 07 : 00 to 19 : 00. For Fig 4 at the whole building scale, E-index is calculated using the median indoor PM2.5 concentration of all indoor sensors for each hour; E-index can also be calculated at zone level, but we do not show these results. This representation visually shows exposure level and duration.
Fig. 4. Exceedance index PM2.5 heat map calculated for WHO 24 h exposure threshold: a) 4th Street and b) Wurster Hall. Results in Fig 4 show that 4th Street whole building E-index was below WHO suggested threshold for 66% of the hours (indicated as E-index of 0) and was one or greater for 34% of the hours, with only 3% being two or greater, meaning that only 3% of the pollution episode hours had median indoor PM2.5 concentration more than or equal to twice the WHO threshold level. Overall average E-index, calculated by averaging hourly values for the entire pollution episode, for 4th Street was 0.82, suggesting that the building as a whole was resilient to outdoor air pollution during this episode, and that the tight building envelope paired with two-staged particle filtration of MERV 8 and MERV 13 at the air handler was effective at blocking PM2.5 penetration and providing acceptable IAQ conditions.
Results for the Wurster Hall show that PM2.5 concentration exceeded the recommended level for 77% of the hours. E-index was in the range from one to less than two for 48% of the hours, from two to less than four for 25% of the hours, and four or above for 3% of the hours. From an hourly analysis, we can see that Wurster Hall had periods that could potentially cause acute effects on occupants, especially for those with pulmonary health issues. One potential way to think about the role of interventions would be to eliminate periods where E-index was above a specified threshold (e.g. level that causes acute effects). For the entire pollution episode, overall average E-index was 1.69, suggesting that Wurster Hall requires intervention in order to be operational during an air pollution episode. Although overall average E-index enables us to compare and rank building resilience performance, the simplification to a single number representation omits important results: that for 29% of the hours Wurster Hall indoor concentration levels exceeded the WHO 24h-mean PM2.5 exposure thresholds by more than two and was at a level that might cause acute health effects during occupied hours.
3.2.2 Cumulative and instantaneous I/O ratio
As described in [17], I/O ratio provides information about the quantity of outdoor particles that enter indoors when indoor sources can be neglected. Considering cumulative I/O ratio at the whole building scale, the median I/O ratio over the entire pollution episode was 0.27 for 4th Street and 0.67 for Wurster Hall. Cumulative whole building I/O ratio is a general indicator of building resilience and can aid in comparing amongst buildings, but it does not contain information on more granular spatial or temporal variations. In Fig 5, we show the cumulative hourly I/O ratio across all sensors and across the entire forest fire event. This can aid in identifying time dependent operational aspects at the whole building scale.
Fig. 5. Hourly distribution of I/O ratios for the whole duration of the air pollution episode caused by the Chico Camp fire (sliding temporal window). In some instances, the cumulative I/O ratio can provide insights about PM2.5 penetration and ingress. As seen in Fig 5, there were trends in I/O ratio by hour of day during the entire pollution episode in each building. The 4th Street had a higher probability of a larger I/O ratio during the HVAC system operating hours compared to the non-operating hours. During this period, median I/O ratio was 0.33 during operating hours compared to 0.21 during non-operating hours. This indicated that PM2.5 ingress is the dominant pathway of outdoor particle entry. The higher I/O ratios observed in Wurster Hall compared to 4th Street is due to the building being less airtight. Wurster Hall has operable windows designed for natural ventilation, and although the windows were closed (based on contact sensor readings) during the pollution event, the CO2 decay rate shows infiltration of 0.4 h-1, as opposed to 0.1 h-1 for 4th Street.
Cumulative I/O ratio can also be viewed on smaller spatial scales, such as individual rooms or zones, which allows for comparison and assessment within a building, similar to the comparison between buildings. We can use cumulative I/O ratio as a tool to assess (post-event) the effectiveness of an intervention, such as changes in building control strategy, economizer regime, air handler filter grade, or changes in recirculated-to-outdoor air ratio. Local level of intervention might improve conditions in a particular room or zone without necessity for larger scale intervention or any significant effect on a building scale.
Cumulative I/O ratio describes overall resilience to an air pollution episode but is limited in that it is only a post-event evaluation tool. IoT sensing can also be used to show instantaneous I/O ratio that can aid in real-time evaluation, such as quickly assessing whether a portable filter is appropriately sized for a room. For example, at the room scale, the instantaneous (e.g., hourly) I/O ratio results in Figs 6A and 7B for Wurster Hall show that different indoor locations can vary from the median building I/O ratio (i.e., the median of all indoor sensors). Fig 6A depicts the effectiveness of a portable filter intervention in room 348 on Nov. 15th. When in use, the portable filter quickly reduced the I/O ratio by more than 50%. The portable filter was manually turned on when the occupant entered the room then off when they left and that was repeated one more time during the day. This results in the sharp decreases and increases in I/O ratio in the middle of the day. Fig 6B shows that room 232, which is adjacent to a hallway with an entrance door to the building, can have ~40% higher instantaneous I/O ratio compared to the whole building median. This is likely due to elevated infiltration of particles caused by opening the entrance doors and movement of people [26]. This space can be considered as a pollution hot zone in the building and interventions should be considered, especially considering that the space had five occupants. As described in the introduction, current guidelines only have qualitative suggestions about portable filters, and this tool enables quantification of effectiveness of that or any intervention.
Fig. 6. Instantaneous I/O ratios comparing median building operation and specific locations: a) operation of portable filter in room 348 and comparison to the building median I/O ratio; b) I/O ratio for the room 232 adjacent to the building exit door. Fig. 7. Instantaneous I/O ratio for the entire building. They are presented for the entire pollution episode with each point represents one hour period a) 4th Street; b) Wurster Hall. Instantaneous I/O ratio can also be viewed at the whole building scale, as shown in Fig 7 which depicts the median I/O ratio from all indoor sensors at each hour for the entire period of the event. Results show that in each hour 4th Street building was more resilient to high outdoor PM2.5 levels and allowed less PM2.5 to enter the building compared to Wurster Hall. In this way, Instantaneous I/O ratio can be used to evaluate the effectiveness of an intervention at the whole building scale in real time, such as increasing the filter grade in air handling units, or adjusting the outdoor air supply rate.
3.2.3 Spatial and temporal variability within the buildings
Placement of indoor PM2.5 sensors is important for the evaluation of the building resilience; however, there is limited guidance on sensor density and appropriate placement. RESET and WELL v2 [27] suggest a sensing densities of one sensor per 500 m2 and one sensor per 325 m2, respectively. Sensing density in the current study was two to five times higher. Results in Fig 8 show by how much measurements at each sensing location deviated from the hourly median calculated for all the sensors. The results show that the majority of deviations at each sensor location in both buildings were within ±10% (the measurement uncertainty), as indicated by the red dashed lines. Most of the sensors in 4th Street were placed in the open plan area, and one sensor was in a private office. Most of the sensors in Wurster Hall were in private offices. In both buildings, the results suggest homogenous PM2.5 distribution under high outdoor pollution levels. Although results show a homogenous environment, we should not draw any general conclusion about the number of sensors necessary to properly characterize the indoor environment for other buildings. A larger sample of buildings would be necessary to determine sensor density.
Fig. 8. Spatial variability of PM2.5 levels represented as percent deviations from the mean level calculated with all the deployed sensors for each building. The red dashed line represents the sensor measurement uncertainty of ±10%: a) 4th Street; b) Wurster Hall. 3.3 Survey of occupants
From the occupant perspective, resilience can be assessed based on how disruptive an air pollution event was to “business as usual” operation. We assessed this using a survey to understand occupants’ air quality perception, self-reported productivity, and behaviour. Survey questions can be found in Supporting Information.
We received 95 complete responses in 4th Street (MV) and 101 in Wurster Hall (NV) from full-time occupants, correlating to response rates of 37% and 34%, respectively. In 4th Street, 78% have worked in the space for more than 1 year, and 89% of respondents work more than 30 hours per week. The demographics of Wurster Hall respondents were similar: 60% have worked in the space for more than 1 year, with the next largest group being those that have worked between 7 to 12 months. 66% of respondents work more than 20 hours per week in the building (45% of respondents work more than 30 hours per week). There was a fairly even distribution across age groups between 21 and over 50 in both buildings. It should be noted that there was minimal campus-wide or building-specific guidance on indoor pollution levels, strategies occupants could take in their workplace, or alternative places to work.
3.3.1 Satisfaction with indoor air quality (IAQ)
Fig 9 shows the results of occupant satisfaction with indoor air quality during typical conditions and during the Chico Camp fire in the two building types. Under typical conditions, occupant satisfaction with IAQ was relatively low in both buildings, with 25% and 41% voting ‘slightly satisfied’ or ‘satisfied’ in 4th Street and Wurster Hall, respectively. There was a statistically significant difference in mean satisfaction scores (p<0.05), with Wurster Hall having higher satisfaction; however, the effect size was small to negligible (d = 0.3). There were 54% and 45% of respondents voting ‘slightly dissatisfied’ or ‘dissatisfied’ with IAQ in 4th Street and Wurster Hall, respectively. The lower satisfaction in 4th Street can be explained by the building’s proximity to a cement facility, and, according to the building manager, occupants often complain of poor IAQ as a result even though there is a mechanical ventilation system.
Fig. 9. Occupant satisfaction with indoor air quality during typical conditions and during the Chico Camp fire in the: a) 4th Street (mechanically ventilated) and b) Wurster Hall (naturally ventilated). Previous studies have found that humans are not accurate sensors of small changes in air pollutant concentrations when exposed to typical levels (i.e., typical to their experience), and that humans associate air quality with aspects of thermal comfort [28–30]. However, the survey responses indicate that during the extreme air pollution event, occupant perception aligned with measured PM2.5 concentrations in the two study buildings. In Wurster Hall, dissatisfaction with IAQ during the forest fire (i.e., votes for ‘slightly dissatisfied’ and ‘dissatisfied’) increased from 45% to 89% of respondents, with a statistically significant difference in mean satisfaction vote (p<0.05) and a moderate to large effect size (d = 1.3) compared to typical conditions. Remarkably, there was only a slight increase in IAQ dissatisfaction from 54% to 57% in 4th Street, and the difference in mean satisfaction vote was not statistically significant (p = 0.48) compared to typical conditions.
The larger increase in dissatisfaction in Wurster Hall than 4th Street aligns with the buildings’ low resilience, as seen in Fig 3 indoor PM2.5 concentrations and Fig 7 PM2.5 exceedance levels, which show that 4th Street was able to maintain indoor PM2.5 concentrations below WHO threshold level most of the time. Notably, under the extreme pollutant conditions during the Chico Camp fire, occupants’ perception of IAQ was in line with measured PM2.5 concentration.
A confounding factor that we could not control is the air temperature in the buildings, which can impact the IAQ perception. Along with mechanical ventilation, 4th Street has air conditioning while Wurster Hall relies on operable windows for cooling. Outdoor temperatures were moderate at the time, with daily temperature highs between 15 to 22°C. From the survey responses, air temperatures were only an issue in Wurster Hall classrooms with high occupancies. Three respondents mentioned that they opened windows or saw windows opened because classrooms became stuffy and hot, and they were forced to make a tradeoff with thermal comfort. Other locations such as private offices where the majority of full-time occupants reside were not likely affected by the air temperatures.
3.3.2 Perceived impact to work productivity
Poor air quality during the Chico Camp fire may have affected productivity by disrupting work schedules or routines, and by causing mental and physical stress on occupants. There is limited research linking wildfire pollutants, including PM2.5 and carbon monoxide, to decreased cognitive abilities. We asked a series of questions to assess how occupants felt IAQ in their workplace affected productivity, including cognitive abilities and psychological state. Responses can help to assess productivity loss during the extreme pollution event and provide information for an intervention cost-benefit analysis [31,32].
Fig 10 shows the self-reported impacts of workplace IAQ on occupants’ ability to get their work done. Similar to occupants’ satisfaction with IAQ in Fig 9, occupants in both buildings reported similar levels of impact under typical conditions, with slightly higher reports of interference in 4th Street. Responses for the Chico Camp fire period are in line with previously reported trends of Wurster Hall occupants reporting more severe impact. Both buildings have statistically significant (p<0.05) difference in mean response between typical conditions and during the Chico Camp fire, but the percent of respondents that reported that workplace IAQ interferes (i.e., considering ‘somewhat interferes’ and ‘interferes’) with productivity increased more in Wurster Hall (38% to 81%) than in 4th Street (45% to 52%) when comparing typical conditions to the Chico Camp fire.
Fig. 10. Occupant self-reported impact of IAQ on their productivity and ability to get their work done a) 4th Street (mechanically ventilated) and b) Wurster Hall (naturally ventilated). In addition to asking directly about productivity, we wanted to understand how occupants felt (i.e., their psychological state) in regards to IAQ once they entered their building from the outside where there was high pollutant concentration, as seen in Figs 3 and 4. Although personal exposure varied by mode of transportation (e.g., by bike, by bus, walking, or by car) and use of N95 face masks, all occupants had some level of exposure and were likely aware of the highly publicized outdoor air quality. The results, shown in Fig 11, have a significant difference (p<0.05) in mean relief vote between the buildings with a small effect size (d = 0.42). More respondents felt relieved in 4th Street and more felt not relieved in Wurster Hall, which aligns with the overall trend of measured performance for those buildings. Although the PM2.5 concentrations in 4th Street were below WHO recommended level the majority of the time, 72% of respondents reported being ‘not relieved’ or only ‘slightly relieved’. This could be due to indoor PM2.5 concentrations being higher than occupants are typically exposed to, unsatisfactory IAQ during typical conditions, or lack of knowledge that indoor pollution was below the risk levels for healthy adults.
Fig. 11. Occupant responses to “When you entered your workspace from the outdoors did you feel relief regarding the air quality?” during the Chico Camp fire. The question assumes that respondents were negatively impacted by outdoor conditions; we included a response for “I was not affected by the outdoor conditions”, indicated as “not affected”. When survey results from Figs 10, 11 and 12 are combined with IoT PM2.5 measurements in Figs 4 and 5, we see a trend that shows occupants perceived lower PM2.5 in 4th Street compared to Wurster Hall. This provides evidence that surveys can be a useful tool in intervention assessment and aid in intervention decision-making during the severe outdoor air pollution events.
Fig. 12. Personal and building features that occupants reported using in their workplace: a) 4th Street (mechanically ventilated) and b) Wurster Hall (naturally ventilated). The option for a face mask was only listed in the forest fire section, and a branching question allowed respondents to indicate if they wore a face mask in their workplace or outdoors. NR is no response given. 3.3.3 Occupant behavior and strategies to reduce exposure
Another approach to understand occupants’ perception of IAQ is by reviewing their actions to reduce exposure to pollutants during the Chico Camp fire. Occupants identified which building features they controlled and what strategies or devices, if any, they used to reduce exposure to pollutants while in their workplace during the Chico Camp fire. The results in Fig 12 shows that 24% in 4th Street and 29% in Wurster Hall wore a face mask in their workplace at some point during the fire. A respondent from Wurster Hall stated, “During the forest fires, smoke filled the room to the point that I was wearing my mask inside.” N95 face masks can reduce individual exposure, but are still a controversial issue especially related to effectiveness of non-fitted masks [13] and recommendations for some groups (e.g., pregnant women, small children, people with respiratory challenges) not to wear them. Additionally, we can reasonably expect that wearing face masks affects productivity by obstructing normal operation within the building, reducing interaction with colleagues, degrading general comfort, and increasing CO2 inhalation which has been linked to cognitive function [33].
While occupants’ direct responses about satisfaction and perceived impacts in each building align with IoT PM2.5 sensing measurements, their reported behavior for wearing face masks did not. Despite indoor PM2.5 concentration being typically below the WHO threshold level in 4th Street and occupants generally reporting higher satisfaction with and lower impact from IAQ during the Chico Camp fire, occupants still wore masks indoors at about the same rate as those in Wurster Hall. The use of face masks in both buildings may have been driven by concern over visual appearance of outdoor air conditions (e.g., grey fog), publicized air quality index (AQI) for outside air, lack of knowledge about air quality in the workplace, and lack of alternative solutions.
Other strategies to avoid pollutant exposure include operating interior doors and windows to the outside in Wurster Hall. As shown in Fig 12, 4th Street occupants did not report high use of any controllable features, mostly because the space is largely open office (i.e., few interior doors) with a limited number of operable windows in select locations. The use of portable air filters was low in both building, with 11% using this device in 4th Street and 16% using in Wurster Hall, less than the number of occupants wearing face masks. We did not collect information on the air filter type or size, but as seen in Fig 6A, a portable air filter can improve IAQ in these events. Some of the possible reasons that portable filters were not more widely used are upfront costs and lack of knowledge or means to measure effectiveness of air filters, which must be properly sized for room volume.
3.3.4 Survey as a building performance assessment tool
Comparing the IoT PM2.5 measurements with the occupant IAQ satisfaction results shows that a survey has the potential to be an effective indicator of general IAQ during the high outdoor air pollution events; however, the survey only provides qualitative information and can assess whether a building is able to maintain “business-as-usual” for occupants. As in the case of Wurster Hall (NV), the survey indicated low IAQ satisfaction, but sensor measurements were necessary to quantify the indoor pollutant concentrations and mechanisms for air pollutant entry into the building. As opposed to the IoT devices, a survey is more often used as a retrospective tool (i.e., can only be applied after the air pollution event occurs), and it could be used to assess the resiliency of buildings or effectiveness of interventions to maintain “business-as-usual”.
As indicated by respondents wearing face masks indoors, maintaining PM2.5 concentration levels within the prescribed limits, either through building level features such as air handler’s filter grade or alternatives solutions like portable air filters, might not be enough to prevent occupants from feeling at risk. A key missing piece was ensuring that occupants are aware of the conditions in the space. Results from this survey only point to this possibility, and need to be validated. Without sensor equipment from this study, neither 4th Street nor Wurster Hall had mechanisms to monitor indoor PM2.5 levels and thus, there was a limited ability to provide building-specific information. This identifies a gap and an additional aspect to consider for a survey to probe into the effectiveness of communicating air quality data.
4. Recommendations for building resilience evaluation
The general trending direction of IoT environmental sensing application and research is to create urban air pollution maps and increase knowledge about the pollution distribution on a city scale; however, this maintains the assumption that outdoor measurement is a good proxy for personal exposure of the entire population within the vicinity of the measurement location. This study shows new and additional value of dense urban environmental IoT sensing networks and addresses the missing gap in integration between urban and building scale IoT sensing, especially considering that humans in developed parts of the world spend approximately 90% of their time indoors [34].
The use of these tools is widespread and can serve several purposes including benchmarking building performance, assessing the effectiveness of interventions, and understanding occupant perception and behavior. Benchmarking building resilience is useful for an entity that manages a large building portfolio (e.g. university campus consisting of ~100 buildings). E-index and I/O ratio are benchmarking tools that can rank and prioritize buildings for improvements and inform occupants of safety. The use and potential applications of these tools at various temporal and spatial scales are listed in Table 2. E-index provides information on exposure level compared to a specified threshold (e.g., WHO) and can identify “safe” buildings or spaces within buildings; similarly, it will identify buildings with high air pollutant exposure or hotspots within buildings. I/O ratio can quickly assess the effectiveness of potential interventions on a whole building or space-by-space scale, such as seen in Fig 6 with the portable air filter. It can also detect pollution hotspots, and predict what indoor pollution would be under different outdoor pollution scenarios. This is important during an extreme pollution event when actions need to be taken immediately. To illustrate the use of exceedance concept, comparison of 4th Street and Wurster Hall for 3 month period excluding forest fire episode is presented in the S3 Fig in Supporting Information. Beyond extreme air pollution events, local and daily pollution sources from vehicle emissions or emissions from factories represent other examples where the IoT sensing tools can help identify issues and characterize building resilience.
Tab. 2. Summary of tools proposed for building resilience evaluation. Creating a database with E-index and/or I/O ratio for a large and diverse set of buildings (i.e., with various typologies, ventilation air delivery strategies, cooling and heating systems, control sequences, facade air tightness, or pressure differentials between indoor and outdoors) will aid in identifying safe buildings and effective practices that can be implemented when extreme air pollution events occur. Together with low-cost IoT sensing, these tools can map out the indoor air pollution risk in a city or campus to inform organizational policies during an extreme event. This could lead to incorporating requirements for building resilience against wildfire-associated air pollution into the design stage of buildings. It can also lead to the development of clean air safe shelters for those at risk, such as homeless people, those who were evacuated from the wildfires affected areas, those with respiratory problems, or those who cannot afford portable filters.
Using the suggested criteria for a resilient building during extreme events, which is to maintain “business as usual” occupant behavior and perception, buildings can be considered successful if occupants feel safe enough indoors not to wear face masks. It is necessary to understand how to achieve this, and one component in this process is collecting IAQ information which can be achieved with IoT sensing. In future work, the survey can be used as an assessment tool and can be reduced to the questions necessary to understand perception and behavior. Additionally, it should include aspects about the effectiveness of methods to increase occupant awareness of indoor air quality during pollution episodes. Further, if IoT sensing measurements are not available or feasible for a building, the study results indicate that occupant perception could be used as a proxy for IAQ; although additional studies in various buildings should be conducted to confirm this.
In interpreting the study results, a few limitations should be recognized. Firstly, sample of only two buildings and a relatively limited number of responses were used for the analysis. As such, the I/O ratio, E-index and occupancy response results reported here cannot be indicative of all buildings and all people. Secondly, the assumption that one local measurement location (placing the sensor on the roof of each of the buildings) is sufficient to represent the outdoor pollution level for the entire building and conclude how the building operates in respect to the penetration of outdoor pollution indoors. Another limitation is a restricted utility of I/O ratio for recommending the specific building interventions, unless used for building resiliency evaluation against the elevated outdoor air pollution. However, the tools can be effective in dry areas prone to wildfires and in heavily polluted cities around the world. Notwithstanding the limitations, our study has not only provided useful preliminary data on which further research, but also offered a methodological contribution towards the assessment of building protection from air pollution of outdoor origin elsewhere.
5. Conclusions
The tools we used in this study are methods to evaluate building resilience to extreme outdoor air pollution episodes using IoT sensing indoors and outdoors, coupled with survey-based information of occupant perception and behaviour. We demonstrated the application of the tools on two buildings with different modes of ventilation. We characterized the resilience of the buildings on different temporal and spatial scales using the well-established I/O ratio and a newly proposed E-index. These tools can be used for a single building or across a portfolio of buildings for resilience ranking. Meanwhile, the survey tool provides qualitative insights on the connection between air pollution levels and occupants’ perception and behavior, which allows assessment of a building’s ability to be resilient, meaning that occupants can maintain “business as usual” view.
Results indicate that even under the extreme outdoor air pollution events, outdoor PM2.5 concentrations can be significantly different across a region, and therefore, outdoor sensors need to be localized to properly evaluate building resilience. Using the tools developed in this study comparing the resilience of mechanically ventilated 4th Street building and naturally ventilated Wurster Hall building indicates:
Indoor PM2.5 concentration over the entire Chico Camp Fire event was 21 μg/m3 for 4th Street and 36 μg/m3 for Wurster Hall. The cumulative median I/O ratio over the entire pollution episode was 0.27 for 4th Street and 0.67 for Wurster Hall. Overall E-index for 4th Street was 0.82, suggesting that the whole building was resilient to air pollution while overall E-index was 1.69 for Wurster Hall suggesting that interventions are necessary in order to be operational during an air pollution episode.
The survey revealed that occupant perception of workplace IAQ aligns with measured PM2.5 in the two buildings, with greater self-reported impacts in Wurster Hall which had significantly worse IAQ than 4th Street. After entering indoor environment coming from outside, occupants in Wurster Hall felt significantly less relieved (p<0.05) than those in 4th Street As many as 31% of occupants that did not feel relieved in Wurster Hall and only 13% in 4th Street Building. The results also revealed that a large portion of occupants wore face masks in both buildings, even though the PM2.5 concentration was below the WHO threshold level. In 4th Street, which was likely driven by lack of alternative solutions and knowledge of PM2.5 levels. This suggests that occupants did not feel or did not know that the indoor air was at the acceptable level. We use this behaviour to suggest criteria for building resiliency.
Supporting information
S3 Fig [tiff]
E-index for 4th Street and Wurster Hall from November 11th until January 28th.S1 Data [csv]
PM2.5 measurments of all sensors from 10/8/2018 until 10/21/2018.
Zdroje
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- Does route matter? Impact of route of oxytocin administration on postpartum bleeding: A double-blind, randomized controlled trial
- Research on OpenCL optimization for FPGA deep learning application
- Drug therapy problems, medication adherence and treatment satisfaction among diabetic patients on follow-up care at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
- Quality of life and symptom intensity over time in people with cancer receiving palliative care: Results from the international European Palliative Care Cancer Symptom study
- The dynamics of Early Celtic consumption practices: A case study of the pottery from the Heuneburg
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- The contribution of age structure to the international homicide decline
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- A cluster-randomized controlled trial of the effectiveness of the JUMP Math program of math instruction for improving elementary math achievement
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- Isoniazid preventive therapy: Uptake, incidence of tuberculosis and survival among people living with HIV in Bulawayo, Zimbabwe
- P16 methylation increases the sensitivity of cancer cells to the CDK4/6 inhibitor palbociclib
- Using long-term datasets to assess the impacts of dietary exposure to neonicotinoids on farmland bird populations in England
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- Consumer beliefs about healthy foods and diets
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- How does the method change what we measure? Comparing virtual reality and text-based surveys for the assessment of moral decisions in traffic dilemmas
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- A social media intervention to improve nutrition knowledge and behaviors of low income, pregnant adolescents and adult women
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- E-MOVIE - Experimental MOVies for Induction of Emotions in neuroscience: An innovative film database with normative data and sex differences
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- An elevated glycemic gap predicts adverse outcomes in diabetic patients with necrotizing fasciitis
- 40-Hz auditory steady-state responses and the complex information processing: An exploratory study in healthy young males
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- Decision-based models of the implementation of interventions in systems of healthcare: Implementation outcomes and intervention effectiveness in complex service environments
- Dual number-based variational data assimilation: Constructing exact tangent linear and adjoint code from nonlinear model evaluations
- Ultra-deep sequencing reveals pre-mRNA splicing as a sequence driven high-fidelity process
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- The organization of Golgi in Drosophila bristles requires microtubule motor protein function and a properly organized microtubule array
- Direct and moderating effects of environmental regulation intensity on enterprise technological innovation: The case of China
- Prevalence and associated factors of depression among Korean adolescents
- Transcriptome analysis of PK-15 cells in innate immune response to porcine deltacoronavirus infection
- Geographic variation in cardiometabolic risk distribution: A cross-sectional study of 256,525 adult residents in the Illawarra-Shoalhaven region of the NSW, Australia
- Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury
- Lipid profile changings after switching from rilpivirine/tenofovir disoproxil fumarate/emtricitabine to rilpivirine/tenofovir alafenamide/emtricitabine: Different effects in patients with or without baseline hypercholesterolemia
- A feature selection strategy for gene expression time series experiments with hidden Markov models
- Dissociating the sequential dependency of subjective temporal order from subjective simultaneity
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- Population-based estimates of engagement in HIV care and mortality using double-sampling methods following home-based counseling and testing in western Kenya
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- Chile (Capsicum annuum) plants transformed with the RB gene from Solanum bulbocastanum are resistant to Phytophthora capsici
- Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study
- Analysis of gene co-expression networks of phosphate starvation and aluminium toxicity responses in Populus spp.
- Risk factors associated with IgA vasculitis with nephritis (Henoch–Schönlein purpura nephritis) progressing to unfavorable outcomes: A meta-analysis
- The prediction model of suicidal thoughts in Korean adults using Decision Tree Analysis: A nationwide cross-sectional study
- A multidimensional understanding of prosperity and well-being at country level: Data-driven explorations
- Factors associated with muscle mass in community-dwelling older people in Singapore: Findings from the SHIELD study
- The prevalence and risk of non-infectious comorbidities in HIV-infected and non-HIV infected men attending general practice in Australia
- Vibrio cholerae strains with inactivated cqsS gene overproduce autoinducer-2 which enhances resuscitation of dormant environmental V. cholerae
- Myocardial function in patients with anomalous left coronary artery from the pulmonary artery syndrome: A long-term speckle tracking echocardiographic study
- Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo
- Joint distribution for number of crossings and longest run in independent Bernoulli observations. The R package crossrun
- Learning to play badminton altered resting-state activity and functional connectivity of the cerebellar sub-regions in adults
- Children’s dietary diversity and related factors in Rwanda and Burundi: A multilevel analysis using 2010 Demographic and Health Surveys
- Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease
- Precluding rare outcomes by predicting their absence
- Tidal inlet seafloor changes induced by recently built hard structures
- A further study on Franciscobasis Machado & Bedê, 2016 (Odonata: Coenagrionidae), a newly described genus from Minas Gerais, Brazil
- Associative responses to visual shape stimuli in the mouse auditory cortex
- Extracellular matrix turnover and inflammation in chemically-induced TMJ arthritis mouse models
- LRP receptors in chondrocytes are modulated by simulated microgravity and cyclic hydrostatic pressure
- Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases
- Separating the effects of temperature and carbon allocation on the diel pattern of soil respiration in the different phenological stages in dry grasslands
- Unweaving tangled mortality and antibiotic consumption data to detect disease outbreaks – Peaks, growths, and foresight in swine production
- Factors associated with exclusive breast-feeding: A cross-sectional survey in Kaiyuan, Yunnan, Southwest China
- The Model of Mortality with Incident Cirrhosis (MoMIC) and the model of Long-term Outlook of Mortality in Cirrhosis (LOMiC)
- Burden of treatment-resistant depression in Medicare: A retrospective claims database analysis
- Genomic characterisation of perinatal Western Australian Streptococcus agalactiae isolates
- Sharing the filmic experience - The physiology of socio-emotional processes in the cinema
- A super-SILAC based proteomics analysis of diffuse large B-cell lymphoma-NOS patient samples to identify new proteins that discriminate GCB and non-GCB lymphomas
- Pneumoproteins are associated with pulmonary function in HIV-infected persons
- Tissue-specific expression of IgG receptors by human macrophages ex vivo
- Electrical impedance myography for the detection of muscle inflammation induced by λ-carrageenan
- Clustering of the structures by using “snakes-&-dragons” approach, or correlation matrix as a signal
- Asymmetric valuation of gains and losses in effort-based decision making
- Genomic and metabolic differences between Pseudomonas putida populations inhabiting sugarcane rhizosphere or bulk soil
- Method comparison for N-glycan profiling: Towards the standardization of glycoanalytical technologies for cell line analysis
- Gender linked fate explains lower legal abortion support among white married women
- L-3,3’,5-triiodothyronine and pregnenolone sulfate inhibit Torpedo nicotinic acetylcholine receptors
- eQTL mapping of rare variant associations using RNA-seq data: An evaluation of approaches
- Cell fishing: A similarity based approach and machine learning strategy for multiple cell lines-compound sensitivity prediction
- Macrogeographic genetic structure of Lutzomyia longipalpis complex populations using Next Generation Sequencing
- Dual-career through the elite university student-athletes’ lenses: The international FISU-EAS survey
- Machine learning prediction of emesis and gastrointestinal state in ferrets
- Impact of bitter tastant sub-qualities on retronasal coffee aroma perception
- Head orientation and electrode placement potentially influence fetal scalp ECG waveform
- Clinical outcomes associated with the use of the NexSite hemodialysis catheter with new exit barrier technology: Results from a prospective, observational multi-center registry study
- Geospatial correlates of early marriage and union formation in Ghana
- Disruption of white matter connectivity in chronic obstructive pulmonary disease
- Integrated evaluation of clinical, pathological and radiological prognostic factors in squamous cell carcinoma of the lung
- Saliva enhances infection of gingival fibroblasts by herpes simplex virus 1
- Pyk2-dependent phosphorylation of LSR enhances localization of LSR and tricellulin at tricellular tight junctions
- An alternative approach for estimating the number needed to treat for survival endpoints
- Bilirubin reduces visceral obesity and insulin resistance by suppression of inflammatory cytokines
- Can telemedicine initiative be an effective intervention strategy for improving treatment compliance for pediatric HIV patients: Evidences on costs and improvement in treatment compliance from Maharashtra, India
- Trial registration as a safeguard against outcome reporting bias and spin? A case study of randomized controlled trials of acupuncture
- Multi-disciplinary interventions for chronic pain involving education: A systematic review
- Impact of climate change on the integrity of the superstructure of deteriorated U.S. bridges
- Switching to bedaquiline for treatment of rifampicin-resistant tuberculosis in South Africa: A retrospective cohort analysis
- Efficacy of Lactobacillus-supplemented triple therapy for H. pylori eradication: A meta-analysis of randomized controlled trials
- Testing gene by community disadvantage moderation of sexual health outcomes among urban women
- The impact of leishmaniasis on mental health and psychosocial well-being: A systematic review
- Evaluation of a screening algorithm using the Strengths and Difficulties Questionnaire to identify children with mental health problems: A five-year register-based follow-up on school performance and healthcare use
- Optimized fast GPU implementation of robust artificial-neural-networks for k-space interpolation (RAKI) reconstruction
- The cost of illness and economic burden of endometriosis and chronic pelvic pain in Australia: A national online survey
- Refined distributed emotion vector representation for social media sentiment analysis
- Enhancing timeliness of drug overdose mortality surveillance: A machine learning approach
- A real-time gesture recognition system using near-infrared imagery
- Alcohol use and its association with sexual risk behaviors in the Armed Forces of the Republic of the Congo
- Improved survival rates in patients with H1N1 acute respiratory failure in Korea between 2009 and 2016
- Electroencephalographic features of discontinuous activity in anesthetized infants and children
- Tumor stromal type is associated with stromal PD-L1 expression and predicts outcomes in breast cancer
- Mutant prevention concentration of ozenoxacin for quinolone-susceptible or -resistant Staphylococcus aureus and Staphylococcus epidermidis
- The Echobot: An automated system for stimulus presentation in studies of human echolocation
- Evaluation of clinical manifestations, health risks, and quality of life among women with polycystic ovary syndrome
- Magnetic resonance imaging presentation of deep infiltrating endometriosis nodules before and after pregnancy: A case series
- Agrobacterium tumefaciens-mediated transformation of a hevein-like gene into asparagus leads to stem wilt resistance
- Effect of a Mentor Mother Programme on retention of mother-baby pairs in HIV care: A secondary analysis of programme data in Uganda
- Utilizing multiplex fluor LAMPs to illuminate multiple gene expressions in situ
- Genetic relationships between the RACK1 homolog cpc-2 and heterotrimeric G protein subunit genes in Neurospora crassa
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- A comparison of the risk of congestive heart failure-related hospitalizations in patients receiving hemodialysis and peritoneal dialysis - A retrospective propensity score-matched study
- A tailored approach to fusion transcript identification increases diagnosis of rare inherited disease
- Experiences, needs, and preferences for follow-up after stroke perceived by people with stroke and healthcare professionals: A focus group study
- Iodine supplementation of lactating women and assessment of infant visual information processing and maternal and infant thyroid function: A randomized trial
- The Nordic Maintenance Care Program: Does psychological profile modify the treatment effect of a preventive manual therapy intervention? A secondary analysis of a pragmatic randomized controlled trial
- Within-subject variability in human retinal nerve fiber bundle width
- Motivation for alcohol consumption or abstinence during pregnancy: A clinical-qualitative study in Brazil
- Comparison of conventional BLUP and single-step genomic BLUP evaluations for yearling weight and carcass traits in Hanwoo beef cattle using single trait and multi-trait models
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- Molecular phylogeny and morphology reveal a new epiphytic species of Habenaria (Orchidaceae; Orchideae; Orchidinae) from Nepal
- Nitrogen nutrition is a key modulator of the sugar and organic acid content in citrus fruit
- Understanding variation in health service coverage and maternal health outcomes among districts in Rwanda – A qualitative study of local health workers’ perceptions
- Biased cognition in East Asian and Western cultures
- Physical fitness and physical self-concept of male and female young adults in Qatar
- Robust policy evaluation from large-scale observational studies
- Improved semi-supervised autoencoder for deception detection
- Delineation of high resolution climate regions over the Korean Peninsula using machine learning approaches
- Are spasticity, weakness, selectivity, and passive range of motion related to gait deviations in children with spastic cerebral palsy? A statistical parametric mapping study
- ProphET, prophage estimation tool: A stand-alone prophage sequence prediction tool with self-updating reference database
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- Time scale of resilience loss: Implications for managing critical transitions in water quality
- Effectiveness of physical and cognitive-behavioural intervention programmes for chronic musculoskeletal pain in adults: A systematic review and meta-analysis of randomised controlled trials
- Relationship between feed efficiency indexes and performance, body measurements, digestibility, energy partitioning, and nitrogen partitioning in pre-weaning dairy heifers
- Long-stay patients in pediatric intensive care unit: Diagnostic-specific definition and predictors
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- Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease
- A systematic review and thematic synthesis of Canada’s LGBTQ2S+ employment, labour market and earnings literature
- The occurrence of ‘Sleeping Beauty’ publications in medical research: Their scientific impact and technological relevance
- Analysis of the protein composition of the spindle pole body during sporulation in Ashbya gossypii
- Assessing undergraduate student and faculty views on animal research: What do they know, whom do they trust, and how much do they care?
- The views and experiences of general dental practitioners (GDP’s) in West Yorkshire who used the International Caries Detection and Assessment System (ICDAS) in research
- Compare HIV/syphilis infections between age groups and explore associated factors of HIV/syphilis co-infections among men who have sex with men in Shenzhen, China, from 2009 to 2017
- Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers
- Effect of exclusive breastfeeding cessation time on childhood morbidity and adverse nutritional outcomes in Ethiopia: Analysis of the demographic and health surveys
- Dual antiplatelet therapy in patients with cirrhosis and acute myocardial infarction – A 13-year nationwide cohort study
- Relationships between electrolyte and amino acid compositions in sweat during exercise suggest a role for amino acids and K+ in reabsorption of Na+ and Cl- from sweat
- A simplified vocal tract model for articulation of [s]: The effect of tongue tip elevation on [s]
- Management and glycemic control of patients with type 2 diabetes mellitus at primary care level in Kedah, Malaysia: A statewide evaluation
- Anabolic steroids among resistance training practitioners
- Factors associated with unsafe abortion practices in Nepal: Pooled analysis of the 2011 and 2016 Nepal Demographic and Health Surveys
- New methods of removing debris and high-throughput counting of cyst nematode eggs extracted from field soil
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- What has reproductive health decision-making capacity got to do with unintended pregnancy? Evidence from the 2014 Ghana Demographic and Health Survey
- Circulating levels of CD34+ cells predict long-term cardiovascular outcomes in patients on maintenance hemodialysis
- Penetration of linezolid into bone tissue 24 h after administration in patients with multidrug-resistant spinal tuberculosis
- Prosthesis design of animal models of periprosthetic joint infection following total knee arthroplasty: A systematic review
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- Effect of tranexamic acid administration on acute traumatic coagulopathy in rats with polytrauma and hemorrhage
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- The impact of PEPFAR transition on HIV service delivery at health facilities in Uganda
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- Correction: Activation of aryl hydrocarbon receptor signaling by a novel agonist ameliorates autoimmune encephalomyelitis
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- Beyond the metabolic syndrome: Visceral and marrow adipose tissues impair bone quantity and quality in Cushing’s disease
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- Behavioral recovery and spinal motoneuron remodeling after polyethylene glycol fusion repair of singly cut and ablated sciatic nerves
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- The intriguing effect of ethanol and nicotine on acetylcholine-sensitive potassium current IKAch: Insight from a quantitative model
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- Turing complete neural computation based on synaptic plasticity
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- 3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
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- Simultaneous cardiac and respiratory inhibition during seizure precedes death in the DBA/1 audiogenic mouse model of SUDEP
- Dopamine receptor antagonists effects on low-dimensional attractors of local field potentials in optogenetic mice
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- Mechanical effects of MitraClip on leaflet stress and myocardial strain in functional mitral regurgitation – A finite element modeling study
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- Seroprevalence of anti-Toxoplasma gondii antibodies in wild boars (Sus scrofa), hunting dogs, and hunters of Brazil
- Detection and determination of stability of the antibiotic residues in cow’s milk
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- Maternal and perinatal outcomes among women with hypertensive disorders in pregnancy in Kumasi, Ghana
- Characteristics and costs in adults with acute poisoning admitted to the emergency department of a university hospital in Belgium
- War pact model of shrinking networks
- Treatment outcomes based on radiation therapy fields for bifocal germinoma: Synchronous or disseminated disease?
- Effect of an intensive 3-day social cognitive treatment (can do treatment) on control self-efficacy in patients with relapsing remitting multiple sclerosis and low disability: A single-centre randomized controlled trial
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- Attitudes and referral practices for pre-exposure prophylaxis (PrEP) among HIV rapid testers and case managers in Philadelphia: A mixed methods study
- The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study
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- An extinction event in planktonic Foraminifera preceded by stabilizing selection
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- The effect of a hiding box on stress levels and body weight in Dutch shelter cats; a randomized controlled trial
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- Deep brain activation patterns involved in virtual gait without and with a doorway: An fMRI study
- Infant dietary intake of yogurt and cheese and gastroenteritis at 1 year of age: The Japan Environment and Children’s Study
- Attenuation of renal fibrosis after unilateral ureteral obstruction in mice lacking the N-type calcium channel
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- SpliceHetero: An information theoretic approach for measuring spliceomic intratumor heterogeneity from bulk tumor RNA-seq
- Large-scale phylogenomic analysis suggests three ancient superclades of the WUSCHEL-RELATED HOMEOBOX transcription factor family in plants
- Plasma sCD36 as non-circadian marker of chronic circadian disturbance in shift workers
- A cross sectional comparison of drug use indicators using WHO methodology in primary level hospitals participating in an Auditable Pharmaceutical Transactions and Services program versus non-APTS primary hospitals in Southern Ethiopia
- Trends in NBA and Euroleague basketball: Analysis and comparison of statistical data from 2000 to 2017
- Liquid biopsies for omics-based analysis in sentinel mussels
- Reporting biases in self-assessed physical and cognitive health status of older Europeans
- Trends in the characteristics of acute primary angle closure in Korea over the past 10-years
- Obesity-associated insulin resistance adversely affects skin function
- First-line treatments in EGFR-mutated advanced non-small cell lung cancer: A network meta-analysis
- In vivo human lower limb muscle architecture dataset obtained using diffusion tensor imaging
- Tobacco smoke exposure as a risk factor for human papillomavirus infections in women 18-26 years old in the United States
- The trigger-information-response model: Exploring health literacy during the first six months following a kidney transplantation
- Factors influencing the behaviour and perceptions of Australian veterinarians towards antibiotic use and antimicrobial resistance
- The development of an evidence-based street food vending model within a socioecological framework: A guide for African countries
- Sociodemographic changes and trends in the rates of new perinatal HIV diagnoses and transmission in Spain from 1997 to 2015
- Patient navigation services for cancer care in low-and middle-income countries: A scoping review
- Weather extremes and perinatal mortality – Seasonal and ethnic differences in northern Sweden, 1800-1895
- Cognitive, relational and task crafting: Spanish adaptation and analysis of psychometric properties of the Job Crafting Questionnaire
- Maternal and perinatal death surveillance and response in Ethiopia: Achievements, challenges and prospects
- Identification and characterisation of capidermicin, a novel bacteriocin produced by Staphylococcus capitis
- Joint emulation of Earth System Model temperature-precipitation realizations with internal variability and space-time and cross-variable correlation: fldgen v2.0 software description
- Extensive culturomics of 8 healthy samples enhances metagenomics efficiency
- Macroepidemiological aspects of porcine reproductive and respiratory syndrome virus detection by major United States veterinary diagnostic laboratories over time, age group, and specimen
- Correction: Low dose naltrexone: Effects on medication in rheumatoid and seropositive arthritis. A nationwide register-based controlled quasi-experimental before-after study
- Correction: Human indole(ethyl)amine-N-methyltransferase (hINMT) catalyzed methylation of tryptamine, dimethylsulfide and dimethylselenide is enhanced under reducing conditions - A comparison between 254C and 254F, two common hINMT variants
- Myofibrillar function differs markedly between denervated and dexamethasone-treated rat skeletal muscles: Role of mechanical load
- Quantitation of eumelanin and pheomelanin markers in diverse biological samples by HPLC-UV-MS following solid-phase extraction
- Kinetics of mean platelet volume predicts mortality in patients with septic shock
- An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug resistance in high grade pancreatic ductal adenocarcinoma
- Combining CDK4/6 inhibitors ribociclib and palbociclib with cytotoxic agents does not enhance cytotoxicity
- Association of Medicaid expansion with health insurance coverage by marital status and sex
- Are current approaches for measuring access to clean water and sanitation inclusive of people with disabilities? Comparison of individual- and household-level access between people with and without disabilities in the Tanahun district of Nepal
- A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage
- Monitoring Universal Health Coverage (UHC) in high Tuberculosis burden countries: Tuberculosis mortality an important tracer of UHC service coverage
- RCT evaluation of Skhokho: A holistic school intervention to prevent gender-based violence among South African Grade 8s
- On the use of Action Units and fuzzy explanatory models for facial expression recognition
- A systematic review of complementary and alternative medicine in oncology: Psychological and physical effects of manipulative and body-based practices
- What factors best explain attitudes to snow leopards in the Nepal Himalayas?
- Determinants of temperature sensitivity of soil respiration with the decline of a foundation species
- Mindfulness meditation, time judgment and time experience: Importance of the time scale considered (seconds or minutes)
- Regional, institutional, and departmental factors associated with gender diversity among BS-level chemical and electrical engineering graduates
- Transepithelial transport of P-glycoprotein substrate by the Malpighian tubules of the desert locust
- Sex affects immunolabeling for histone 3 K27me3 in the trophectoderm of the bovine blastocyst but not labeling for histone 3 K18ac
- A survey of public attitudes toward uterus transplantation, surrogacy, and adoption in Japan
- Replacing plasma membrane outer leaflet lipids with exogenous lipid without damaging membrane integrity
- Accurate dried blood spots collection in the community using non-medically trained personnel could support scaling up routine viral load testing in resource limited settings
- Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study
- Antimicrobial efficacy of commercially available endodontic bioceramic root canal sealers: A systematic review
- The motility-based swim-up technique separates bull sperm based on differences in metabolic rates and tail length
- Synbiotic supplementation to decrease Salmonella colonization in the intestine and carcass contamination in broiler birds
- Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease
- States with higher minimum wages have lower STI rates among women: Results of an ecological study of 66 US metropolitan areas, 2003-2015
- Weakening the subjective sensation of own hand ownership does not interfere with rapid finger movements
- Identification of DNA methyltransferases and demethylases in Solanum melongena L., and their transcription dynamics during fruit development and after salt and drought stresses
- Environmental conditions for Jamestown Canyon virus correlated with population-level resource selection by white-tailed deer in a suburban landscape
- The contribution of linear perspective cues and texture gradients in the perceptual rescaling of stimuli inside a Ponzo illusion corridor
- Cerebral blood flow imbalance is associated with motor outcome after pediatric arterial ischemic stroke
- Particularly neglected in countries with other challenges: High Toxoplasma gondii seroprevalence in pregnant women in Kabul, Afghanistan, while a low proportion know about the parasite
- Implementing advance care planning in routine nursing home care: The development of the theory-based ACP+ program
- Identifying genetic lineages through shape: An example in a cosmopolitan marine turtle species using geometric morphometrics
- The causality of borrowing: Lexical loans in Eurasian languages
- The uptake of the pharmacy-dispensed naloxone kit program in Ontario: A population-based study
- Gaze and body cues interplay during interactive requests
- Acetylcholine-mediated top-down attention improves the response to bottom-up inputs by deformation of the attractor landscape
- Deep architectures for long-term stock price prediction with a heuristic-based strategy for trading simulations
- Vaccination status of patients using anti-TNF therapy and the physicians’ behavior shaping the phenomenon: Mixed-methods approach
- Organizational justice and illness reporting among Japanese employees with chronic diseases
- CavBench: A benchmark for protein cavity detection methods
- Antimicrobial resistance (AMR) and molecular characterization of Neisseria gonorrhoeae in Ghana, 2012-2015
- Prevalence of methicillin-resistant Staphylococcus aureus in healthy Chinese population: A system review and meta-analysis
- Suppression treatment differentially influences the microbial community and the occurrence of broad host range plasmids in the rhizosphere of the model cover crop Avena sativa L.
- Risk of pneumonia among residents living near goat and poultry farms during 2014-2016
- Lipid levels after childbirth and association with number of children: A population-based cohort study
- Birth outcomes in women who have taken adalimumab in pregnancy: A prospective cohort study
- ECMO with vasopressor use during early endotoxic shock: Can it improve circulatory support and regional microcirculatory blood flow?
- Effects of dietary intake and nutritional status on cerebral oxygenation in patients with chronic kidney disease not undergoing dialysis: A cross-sectional study
- Micro-RNA 150-5p predicts overt heart failure in patients with univentricular hearts
- Flexible learning spaces facilitate interaction, collaboration and behavioural engagement in secondary school
- Clinical significance and prognostic role of hypoxia-induced microRNA 382 in gastric adenocarcinoma
- Genome-wide investigation of superoxide dismutase (SOD) gene family and their regulatory miRNAs reveal the involvement in abiotic stress and hormone response in tea plant (Camellia sinensis)
- Classifying recurrent Mycobacterium tuberculosis cases in Georgia using MIRU-VNTR typing
- Prevalence of Trypanosoma cruzi infection in active military population of The Colombian National Army gathered in five departments
- An observational study comparing HPV prevalence and type distribution between HPV-vaccinated and -unvaccinated girls after introduction of school-based HPV vaccination in Norway
- Sarcopenia as a prognostic factor for survival in patients with locally advanced gastroesophageal adenocarcinoma
- Increased aggression and reduced aversive learning in honey bees exposed to extremely low frequency electromagnetic fields
- Attending to design when developing complex health interventions: A qualitative interview study with intervention developers and associated stakeholders
- Increased fecundity of Aphis fabae on Vicia faba plants following seed or leaf inoculation with the entomopathogenic fungus Beauveria bassiana
- Is summer food intake a limiting factor for boreal browsers? Diet, temperature, and reproduction as drivers of consumption in female moose
- Characterization of sound scattering layers in the Bay of Biscay using broadband acoustics, nets and video
- Conducting human challenge studies in LMICs: A survey of researchers and ethics committee members in Thailand
- eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization
- Clinical use of SAND battery to evaluate language in patients with Progressive Supranuclear Palsy
- The interplay of personality and attitudes toward own aging across two decades of later life
- Robust automated reading of the skin prick test via 3D imaging and parametric surface fitting
- Reconstructing the population history of the sandy beach amphipod Haustorioides japonicus using the calibration of demographic transition (CDT) approach
- A psychoacoustic application for the adjustment of electrical hearing thresholds in cochlear implant patients
- Correction: Blue light-dependent human magnetoreception in geomagnetic food orientation
- Re-evaluation of a Tn5::gacA mutant of Pseudomonas syringae pv. tomato DC3000 uncovers roles for uvrC and anmK in promoting virulence
- Sugar-sweetened beverages and colorectal cancer risk in the California Teachers Study
- Illuminating biological pathways for drug targeting in head and neck squamous cell carcinoma
- The impact of shared knowledge on speakers’ prosody
- Effects of insecticides, fipronil and imidacloprid, on the growth, survival, and behavior of brown shrimp Farfantepenaeus aztecus
- Prevalence of pectus excavatum (PE), pectus carinatum (PC), tracheal hypoplasia, thoracic spine deformities and lateral heart displacement in thoracic radiographs of screw-tailed brachycephalic dogs
- Validation of the vignette-based German Exercise Causality Orientation Scale (G-ECOS)
- Hierarchical classification of snowmelt episodes in the Pyrenees using seismic data
- A national survey of videolaryngoscopes and alternative intubation devices in Hungary
- The relevance of U.S. Strategic Highway Safety Plans in a future context
- Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs
- Anti-inflammatory effects induced by ultralow concentrations of bupivacaine in combination with ultralow concentrations of sildenafil (Viagra) and vitamin D3 on inflammatory reactive brain astrocytes
- Access to unauthorized hepatitis C generics: Perception and knowledge of physicians, pharmacists, patients and non-healthcare professionals
- Urban commuting dynamics in response to public transit upgrades: A big data approach
- Intestinal mucosal injury induced by obstructive jaundice is associated with activation of TLR4/TRAF6/NF-κB pathways
- When resolution does matter: Modelling indirect contacts in dairy farms at different levels of detail
- Molecular epidemiology of Mycoplasma hyorhinis porcine field isolates in the United States
- Liquorice ingestion attenuates vasodilatation via exogenous nitric oxide donor but not via β2-adrenoceptor stimulation
- Adolescents living with HIV are at higher risk of death and loss to follow up from care: Analysis of cohort data from eight health facilities in Ethiopia
- Identification of social relation within pedestrian dyads
- Blood donation and health status based on SF-36: The mediating effect of cognition in blood donation
- The cost-effectiveness of controlling cervical cancer using a new 9-valent human papillomavirus vaccine among school-aged girls in Australia
- Inactivation of chronic wasting disease prions using sodium hypochlorite
- Analysing linear multivariate pattern transformations in neuroimaging data
- Ecological aesthetic assessment of a rebuilt wetland restored from farmland and management implications for National Wetland Parks
- A method for predicting background advertisement exposure parameters in sporting events: Televised football game approach
- Self-reported and experimentally induced self-disgust is heightened in Parkinson’s disease: Contribution of behavioural symptoms
- Associations between nocturnal sleep duration, midday nap duration and body composition among adults in Southwest China
- Short-term effects of video gaming on brain response during working memory performance
- Molecular detection and genetic characterization of Bartonella species from rodents and their associated ectoparasites from northern Tanzania
- Estimation of the number of HCV-positive patients in Italy
- Comparative cost analysis of point-of-care versus laboratory-based testing to initiate and monitor HIV treatment in South Africa
- Insights into the behavior of six rationally designed peptides based on Escherichia coli’s OmpA at the water-dodecane interface
- Identification of muscle-specific candidate genes in Simmental beef cattle using imputed next generation sequencing
- A game theoretic setting of capitation versus fee-for-service payment systems
- In utero exposure to economic fluctuations and birth outcomes: An analysis of the relevance of the local unemployment rate in Brazilian state capitals
- QTL mapping for aluminum tolerance in RIL population of soybean (Glycine max L.) by RAD sequencing
- Establishing an infrastructure for collaboration in primate cognition research
- Evaluation of left ventricular dimension and systolic function by standard transthoracic echocardiography before and 24-hours after percutaneous closure of patent ductus arteriosus in 120 dogs
- Modeling environmental variability and network formation among pastoral nomadic households: Implications for the rise of the Mongol Empire
- Changes in real-life practice for hepatocellular carcinoma patients in the Republic of Korea over a 12-year period: A nationwide random sample study
- Correction: Homology analysis of malware based on ensemble learning and multifeatures
- Illness beliefs and emotional responses in mildly disabled stroke survivors: A qualitative study
- Extended-wavelength diffuse reflectance spectroscopy with a machine-learning method for in vivo tissue classification
- Modeling the natural history of fatty liver using lifestyle–related risk factors: Effects of body mass index (BMI) on the life–course of fatty liver
- Development of a recombinant replication-deficient rabies virus-based bivalent-vaccine against MERS-CoV and rabies virus and its humoral immunogenicity in mice
- Educational achievement at age 9.5 years of children born to mothers maintained on methadone during pregnancy
- Comparative transcriptome analysis of galls from four different host plants suggests the molecular mechanism of gall development
- Experiences with peer support for breastfeeding in Beirut, Lebanon: A qualitative study
- Elucidating optical field directed hierarchical self-assembly of homogenous versus heterogeneous nanoclusters with femtosecond optical tweezers
- Structure establishment of three-dimensional (3D) cell culture printing model for bladder cancer
- Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality
- Correction: Functional atlases for analysis of motor and neuropsychological outcomes after medial globus pallidus and subthalamic stimulation
- Correction: Estimating Body Composition in Adolescent Sprint Athletes: Comparison of Different Methods in a 3 Years Longitudinal Design
- Quality of labor and birth care in Sindh Province, Pakistan: Findings from direct observations at health facilities
- A comparison of sLASER and MEGA-sLASER using simultaneous interleaved acquisition for measuring GABA in the human brain at 7T
- Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis
- Intrabladder pressure as predictor of intra-abdominal pressure in horses
- Pollock avoided hydrodynamic instabilities to paint with his dripping technique
- Metabolomic analysis of the occurrence of bitter fruits on grafted oriental melon plants
- Photo-degradation dynamics of five neonicotinoids: Bamboo vinegar as a synergistic agent for improved functional duration
- Use of acoustic emission to identify novel candidate biomarkers for knee osteoarthritis (OA)
- Cetacean biodiversity, spatial and temporal trends based on stranding records (1920-2016), Victoria, Australia
- Neutrophil elastase inhibitor purification strategy from cowpea seeds
- Correction: Hafting of Middle Paleolithic tools in Latium (central Italy): New data from Fossellone and Sant’Agostino caves
- Coherent poly propagation materials with 3-dimensional photonic control over visible light
- Characterization of Worldwide Olive Germplasm Banks of Marrakech (Morocco) and Córdoba (Spain): Towards management and use of olive germplasm in breeding programs
- Can non-pharmacological interventions reduce hospital admissions in people with dementia? A systematic review
- Metarhizium robertsii ammonium permeases (MepC and Mep2) contribute to rhizoplane colonization and modulates the transfer of insect derived nitrogen to plants
- Genotyping and antimicrobial resistance of Streptococcus uberis isolated from bovine clinical mastitis
- Isotopic compositions of ground ice in near-surface permafrost in relation to vegetation and microtopography at the Taiga–Tundra boundary in the Indigirka River lowlands, northeastern Siberia
- Financial inclusion and intimate partner violence: What does the evidence suggest?
- Are intestinal helminths playing a positive role in tuberculosis risk? A systematic review and meta-analysis
- Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition
- Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer
- Take one step backward to move forward: Assessment of genetic diversity and population structure of captive Asian woolly-necked storks (Ciconia episcopus)
- Money doesn’t matter! Householders’ intentions to reduce standby power are unaffected by personalised pecuniary feedback
- Validating a scale to measure engineers’ perceived self-efficacy for engineering education outreach
- Effect of d-cycloserine on fear extinction training in adults with social anxiety disorder
- Nursing students and nurses’ knowledge and attitudes regarding children’s pain: A comparative cross-sectional study
- Inter-method and anatomical correlates of episodic memory tests in the Alzheimer’s Disease spectrum
- Knowledge, attitudes and medical practice regarding hepatitis B prevention and management among healthcare workers in Northern Vietnam
- Development and validation of a symptom assessment tool for postmicturition dribble: A prospective, multicenter, observational study in Korea
- Identification of closely related Ixodes species by protein profiling with MALDI-TOF mass spectrometry
- When calculators lie: A demonstration of uncritical calculator usage among college students and factors that improve performance
- Socio-economic characteristics and career intentions of the WiSDOM health professional cohort in South Africa
- Correction: Neural computational model GrowthEstimate: A model for studying living resources through digestive efficiency
- Social proximity in dairy calves is affected by differences in pessimism
- Amphibian skin-associated Pigmentiphaga: Genome sequence and occurrence across geography and hosts
- Expanded consumer niche widths may signal an early response to spatial protection
- Moral grandstanding in public discourse: Status-seeking motives as a potential explanatory mechanism in predicting conflict
- Adipose stem cells in reparative goat mastitis mammary gland
- Seventy-five mosses and liverworts found frozen with the late Neolithic Tyrolean Iceman: Origins, taphonomy and the Iceman’s last journey
- Hyaluronic acid and epidermal growth factor improved the bovine embryo quality by regulating the DNA methylation and expression patterns of the focal adhesion pathway
- Associations among knowledge, attitudes, and practices toward palliative care consultation service in healthcare staffs: A cross-sectional study
- A novel, wearable, electronic visual aid to assist those with reduced peripheral vision
- Genetic diversity and population structure of the Mediterranean sesame core collection with use of genome-wide SNPs developed by double digest RAD-Seq
- Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression
- Mobile health-based physical activity intervention for individuals with spinal cord injury in the community: A pilot study
- Factors influencing cultivated ginseng (Panax ginseng C. A. Meyer) bioactive compounds
- Estimation of soil pH with geochemical indices in forest soils
- Multiplexed editing of a begomovirus genome restricts escape mutant formation and disease development
- Correlates of longitudinal leukocyte telomere length in the Costa Rican Longevity Study of Healthy Aging (CRELES): On the importance of DNA collection and storage procedures
- Collaboration and followership: A stochastic model for activities in social networks
- Evaluating access to oral anti-diabetic medicines: A cross-sectional survey of prices, availability and affordability in Shaanxi Province, Western China
- Comparison of corneal elevation and pachymetry measurements made by two state of the art corneal tomographers with different measurement principles
- Use of a pressure-sensing walkway system for biometric assessment of gait characteristics in goats
- Current status and direct medical cost of amyotrophic lateral sclerosis in the region of Catalonia: A population-based analysis
- Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion
- Can work climate foster pro-environmental behavior inside and outside of the workplace?
- Gene editing of PKLR gene in human hematopoietic progenitors through 5’ and 3’ UTR modified TALEN mRNA
- Pelvic alignment changes during the perinatal period
- Interatrial blocks prevalence and risk factors for human immunodeficiency virus-infected persons
- Life-course trajectories of body mass index and subsequent cardiovascular risk among Chinese population
- Inhibitory interaction networks among coevolved Streptomyces populations from prairie soils
- Exploiting contextual information to improve call prediction
- Visual inputs decrease brain activity in frontal areas during silent lipreading
- The synergistic effects of TaAGP.L-B1 and TaSSIVb-D mutations in wheat lead to alterations of gene expression patterns and starch content in grain development
- Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets
- Robust, real-time generic detector based on a multi-feature probabilistic method
- Maize leaves drought-responsive genes revealed by comparative transcriptome of two cultivars during the filling stage
- Xenon lamps used for fruit surface sterilization can increase the content of total flavonols in leaves of Lactuca sativa L. without any negative effect on net photosynthesis
- An alternative procedure to obtain the mortality rate with non-linear functions: Application to the case of the Spanish population
- Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis
- Longitudinal assessment of post-surgical physical activity in endometrial and ovarian cancer patients
- THINGS: A database of 1,854 object concepts and more than 26,000 naturalistic object images
- Evaluation of ranibizumab and aflibercept for the treatment of diabetic macular edema in daily clinical practice
- Proteomic analysis of Escherichia coli detergent-resistant membranes (DRM)
- Correction: Effect of curcuminoids and curcumin derivate products on thioredoxin-glutathione reductase from Taenia crassiceps cysticerci. Evidence suggesting a curcumin oxidation product as a suitable inhibitor
- Correction: Predicting childhood obesity using electronic health records and publicly available data
- Correction: Estimating the value of tropical coastal wetland habitats to fisheries: Caveats and assumptions
- Correction: The effects of sympathetic activity induced by ice water on blood flow and brachial artery flow-mediated dilatation response in healthy volunteers
- Determinants of frailty development and progression using a multidimensional frailty index: Evidence from the English Longitudinal Study of Ageing
- Supporting informed clinical trial decisions: Results from a randomized controlled trial evaluating a digital decision support tool for those with intellectual disability
- BMAL1 associates with chromosome ends to control rhythms in TERRA and telomeric heterochromatin
- Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry
- Hepatopulmonary syndrome has low prevalence of pulmonary vascular abnormalities on chest computed tomography
- Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
- Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15
- The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population
- Expression of Concern: The Coordination of Cell Growth during Fission Yeast Mating Requires Ras1-GTP Hydrolysis
- Correction: Lentivirus-Mediated Knockdown of Astrocyte Elevated Gene-1 Inhibits Growth and Induces Apoptosis through MAPK Pathways in Human Retinoblastoma Cells
- Relationship between self-disclosure to first acquaintances and subjective well-being in people with schizophrenia spectrum disorders living in the community
- Remarkable cell recovery from cerebral ischemia in rats using an adaptive escalator-based rehabilitation mechanism
- Integrating environmental and neighborhood factors in MaxEnt modeling to predict species distributions: A case study of Aedes albopictus in southeastern Pennsylvania
- Post-overdose interventions triggered by calling 911: Centering the perspectives of people who use drugs (PWUDs)
- The prevalence of intimate partner violence among couples signing up for universally offered parent preparation
- Analysis of gear surface morphology based on gray level co-occurrence matrix and fractal dimension
- Abiotic, present-day and historical effects on species, functional and phylogenetic diversity in dry grasslands of different age
- Clonality analysis of pulmonary tumors by genome-wide copy number profiling
- A relictual troglomorphic harvestman discovered in a volcanic cave of western Argentina: Otilioleptes marcelae, new genus, new species, and Otilioleptidae, new family (Arachnida, Opiliones, Gonyleptoidea)
- HIV drug resistance in persons who inject drugs enrolled in an HIV prevention trial in Indonesia, Ukraine, and Vietnam: HPTN 074
- Dietary acid load significantly predicts 10-years survival in patients underwent coronary artery bypass grafting (CABG) surgery
- Regulation of nitrogen availability results in changes in grain protein content and grain storage subproteomes in barley (Hordeum vulgare L.)
- Diagnostic test evaluation methodology: A systematic review of methods employed to evaluate diagnostic tests in the absence of gold standard – An update
- Longitudinal trends of and factors associated with inappropriate antibiotic prescribing for non-bacterial acute respiratory tract infection in Japan: A retrospective claims database study, 2012–2017
- Revealing users’ experience and social interaction outcomes following a web-based smoking prevention intervention for adolescents: A qualitative study
- Coordination of human movements resulting in motor strategies exploited by skilled players during a throwing task
- Impact of pericardiectomy on exercise capacity and sleep of patients with chronic constrictive pericarditis
- Blue-violet light decreases VEGFa production in an in vitro model of AMD
- Identification of protein changes in the blood plasma of lung cancer patients subjected to chemotherapy using a 2D-DIGE approach
- Speed of processing training and depression in assisted and independent living: A randomized controlled trial
- Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient
- What happens in the brain of meditators when perception changes but not the stimulus?
- Comparison of HIV-1 Vif and Vpu accessory proteins for delivery of polyepitope constructs harboring Nef, Gp160 and P24 using various cell penetrating peptides
- Are degree of urbanisation and travel times to healthcare services associated with the processes of care and outcomes of heart failure? A retrospective cohort study based on administrative data
- A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing
- Influence of transcutaneous vagus nerve stimulation on cardiac vagal activity: Not different from sham stimulation and no effect of stimulation intensity
- Co-prescription network reveals social dynamics of opioid doctor shopping
- Contractile properties of superficial skeletal muscle affect postural control in healthy young adults: A test of the rambling and trembling hypothesis
- Does intrauterine crowding affect the force generating capacity and muscle composition of the piglet front limb?
- Correction: Measuring compassionate healthcare with the 12-item Schwartz Center Compassionate Care Scale
- Facilitators and barriers to traditional medicine use among cancer patients in Malawi
- Expression of CMV protein pp65 in cutaneous malignant melanoma
- The evolution of mental health outcomes across a combat deployment cycle: A longitudinal study of a Guam-based National Guard unit
- Caesarean section delivery and childhood obesity in a British longitudinal cohort study
- Incidence, characteristics, and mortality of infective endocarditis in France in 2011
- Pfcyp51 exclusively determines reduced sensitivity to 14α-demethylase inhibitor fungicides in the banana black Sigatoka pathogen Pseudocercospora fijiensis
- Evaluation of the bacterial ocular surface microbiome in clinically normal cats before and after treatment with topical erythromycin
- Histological and developmental insights into the herbivorous dentition of tapinocephalid therapsids
- Differential immunomodulation of T-cells by immunoglobulin replacement therapy in primary and secondary antibody deficiency
- A longitudinal study on perceived health in cardiovascular patients: The role of conscientiousness, subjective wellbeing and cardiac self-efficacy
- The effectiveness of interferon beta versus glatiramer acetate and natalizumab versus fingolimod in a Polish real-world population
- Interactions of Streptococcus suis serotype 9 with host cells and role of the capsular polysaccharide: Comparison with serotypes 2 and 14
- Honey bee and native solitary bee foraging behavior in a crop with dimorphic parental lines
- A flexible formula for incorporating distributive concerns into cost-effectiveness analyses: Priority weights
- Correction: Lack of association between hypothyroxinemia of prematurity and transient thyroid abnormalities with adverse long term neurodevelopmental outcome in very low birth weight infants
- A reconnaissance survey of farmers’ awareness of hypomagnesaemic tetany in UK cattle and sheep farms
- Health workers’ perception of malaria rapid diagnostic test and factors influencing compliance with test results in Ebonyi state, Nigeria
- Conformational flexibility of fork-remodeling helicase Rad5 shown by full-ensemble hybrid methods
- The increasing importance of fellowships and career development awards in the careers of early-stage biomedical academic researchers
- Occurrence and stability of hetero-hexamer associations formed by β-carboxysome CcmK shell components
- Auxin driven indoleamine biosynthesis and the role of tryptophan as an inductive signal in Hypericum perforatum (L.)
- Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development
- Distance to large rivers affects fish diversity patterns in highly dynamic streams of Central Amazonia
- Real vs. immersive-virtual emotional experience: Analysis of psycho-physiological patterns in a free exploration of an art museum
- Modulation of brain tumor risk by genetic SNPs in PARP1gene: Hospital based case control study
- Processed meat intake and chronic disease morbidity and mortality: An overview of systematic reviews and meta-analyses
- Modeling ENSO impact on rice production in the Mekong River Delta
- The feasibility of a behavioral group intervention after weight-loss surgery: A randomized pilot trial
- EMR-integrated minimal core dataset for routine health care and multiple research settings: A case study for neuroinflammatory demyelinating diseases
- A review of a 13-month period of FilmArray Meningitis/Encephalitis panel implementation as a first-line diagnosis tool at a university hospital
- Increased BMI has a linear association with late-onset preeclampsia: A population-based study
- Autoantibody production significantly decreased with APRIL/BLyS blockade in murine chronic rejection kidney transplant model
- Vancomycin-resistance gene cluster, vanC, in the gut microbiome of acute leukemia patients undergoing intensive chemotherapy
- Telomere length in COPD: Relationships with physical activity, exercise capacity, and acute exacerbations
- Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP
- Impact of faecal calprotectin measurement on clinical decision-making in patients with Crohn’s disease and ulcerative colitis
- Additive effects of a small molecular PCNA inhibitor PCNA-I1S and DNA damaging agents on growth inhibition and DNA damage in prostate and lung cancer cells
- Autophagy is important to the acidogenic metabolism of Aspergillus niger
- Continuous ratings of movie watching reveal idiosyncratic dynamics of aesthetic enjoyment
- Sensitivity and specificity of serum soluble interleukin-2 receptor for diagnosing sarcoidosis in a population of patients suspected of sarcoidosis
- Enhancing genomic selection by fitting large-effect SNPs as fixed effects and a genotype-by-environment effect using a maize BC1F3:4 population
- Quantitation and modeling of post-translational modifications in a therapeutic monoclonal antibody from single- and multiple-dose monkey pharmacokinetic studies using mass spectrometry
- Microbial induced solidification and stabilization of municipal solid waste incineration fly ash with high alkalinity and heavy metal toxicity
- Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses
- A fault-tolerant aware scheduling method for fog-cloud environments
- Correction: BCG vaccination and tuberculosis prevention: A forty years cohort study, Monastir, Tunisia
- Correction: Perceptions among transgender women of factors associated with the access to HIV/AIDS-related health services in Yogyakarta, Indonesia
- Assessing the convergent validity between the automated emotion recognition software Noldus FaceReader 7 and Facial Action Coding System Scoring
- Deep learning based banana plant detection and counting using high-resolution red-green-blue (RGB) images collected from unmanned aerial vehicle (UAV)
- Comparison of cardiorespiratory fitness between preschool children with normal and excess body adipose ~ An observational study
- Intraregional differences in renal function in the Northern Netherlands: The Lifelines Cohort Study
- Effects of MCHM on yeast metabolism
- Signaling impacts of GMO labeling on fruit and vegetable demand
- Dietary specialization depending on ecological context and sexual differences in Asiatic black bears
- Electronic device use and beverage related sugar and caffeine intake in US adolescents
- Isolation and characterization of five novel probiotic strains from Korean infant and children faeces
- Correction: Silymarin in non-cirrhotics with non-alcoholic steatohepatitis: A randomized, double-blind, placebo controlled trial
- Correction: Anatomical analysis of antebrachial cutaneous nerve distribution pattern and its clinical implications for sensory reconstruction
- Endothelial nitric oxide synthase limits host immunity to control disseminated Candida albicans infections in mice
- Lack of detection of Candida nivariensis and Candida bracarensis among 440 clinical Candida glabrata sensu lato isolates in Kuwait
- Nonlinear dynamics captures brain states at different levels of consciousness in patients anesthetized with propofol
- Visual encounters on line transect surveys under-detect carnivore species: Implications for assessing distribution and conservation status
- Menstrual health communication among Indian adolescents: A mixed-methods study
- Fast fluorescence in situ hybridisation for the enhanced detection of MET in non-small cell lung cancer
- The influence of personality on the effect of iTBS after being stressed on cortisol secretion
- Parental and peer support and modelling in relation to domain-specific physical activity participation in boys and girls from Germany
- Oral delivery of water-soluble compounds to the phytoseiid mite Neoseiulus californicus (Acari: Phytoseiidae)
- Force perceptual bias caused by muscle activity in unimanual steering
- Correction: Comparison of risk models for mortality and cardiovascular events between machine learning and conventional logistic regression analysis
- Correction: Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium
- Providencia entomophila sp. nov., a new bacterial species associated with major olive pests in Tunisia
- Safety of intravitreal ziv-aflibercept in choroido-retinal vascular diseases: A randomised double-blind intervention study
- A novel framework for evaluating the impact of individual decision-making on public health outcomes and its potential application to study antiviral treatment collection during an influenza pandemic
- Reduction of the rocuronium-induced withdrawal reflex by MR13A10A, a generic rocuronium with a novel solution: A randomized, controlled study
- Emotionally expressed voices are retained in memory following a single exposure
- Megabenthic communities of the Ligurian deep continental shelf and shelf break (NW Mediterranean Sea)
- Election forensics: Using machine learning and synthetic data for possible election anomaly detection
- A randomized crossover trial comparing the Nifty cup to a medicine cup in preterm infants who have difficulty breastfeeding at Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana
- The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease
- Genomic impact of severe population decline in a nomadic songbird
- Evolution of high-sensitivity troponin-T and echocardiography parameters in patients undergoing high efficiency on-line hemodiafiltration versus conventional low-flux hemodialysis
- Full genome characterization of 12 citrus tatter leaf virus isolates for the development of a detection assay
- Intake of myo-inositol hexaphosphate and urinary excretion of inositol phosphates in Wistar rats: Gavage vs. oral administration with sugar
- Enhancing financial security of female sex workers through a community-led intervention in India: Evidence from a longitudinal survey
- In-silico prediction of novel genes responsive to drought and salinity stress tolerance in bread wheat (Triticum aestivum)
- Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
- Partitioning the risk of tuberculosis transmission in household contact studies
- Recommendation system in social networks with topical attention and probabilistic matrix factorization
- Using satellite-measured relative humidity for prediction of Metisa plana’s population in oil palm plantations: A comparative assessment of regression and artificial neural network models
- A drug interaction study investigating the effect of Rifabutin on the pharmacokinetics of Maraviroc in healthy subjects
- Emotional and behavioral problems, social competence and risk factors in 6–16-year-old students in Beijing, China
- Clinicopathologic and prognostic significance of tumor-associated macrophages in patients with hepatocellular carcinoma: A meta-analysis
- Involution of retinopathy of prematurity and neurodevelopmental outcomes after intravitreal bevacizumab treatment
- Travel demand and distance analysis for free-floating car sharing based on deep learning method
- Genome-wide identification, characterization, expression and enzyme activity analysis of coniferyl alcohol acetyltransferase genes involved in eugenol biosynthesis in Prunus mume
- Population analysis of D6-like plasmid prophage variants associated with specific IncC plasmid types in the emerging Salmonella Typhimurium ST213 genotype
- The high resource impact of reformatting requirements for scientific papers
- Egg yolk-free cryopreservation of bull semen
- Fine epitope mapping of glycoprotein Gn in Guertu virus
- Are hospital nurse staffing practices associated with postoperative cardiac events and death? A systematic review
- Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction
- Aging and the wandering brain: Age-related differences in the neural correlates of stimulus-independent thoughts
- Elucidating stygofaunal trophic web interactions via isotopic ecology
- Experimental characterization of two archaeal inosine 5'-monophosphate cyclohydrolases
- Scientist and data architect collaborate to curate and archive an inner ear electrophysiology data collection
- No effect of triple-pulse TMS medial to intraparietal sulcus on online correction for target perturbations during goal-directed hand and foot reaches
- Correction: Controlling Social Stress in Virtual Reality Environments
- TNF-α is responsible for the contribution of stromal cells to osteoclast and odontoclast formation during orthodontic tooth movement
- Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children
- Alteration of humoral, cellular and cytokine immune response to inactivated influenza vaccine in patients with Sickle Cell Disease
- To tweet or not to tweet, that is the question: A randomized trial of Twitter effects in medical education
- Visualizing a field of research: A methodology of systematic scientometric reviews
- True Colors: Commercially-acquired morphological genotypes reveal hidden allele variation among dog breeds, informing both trait ancestry and breed potential
- Impact of the detection of ζ-globin chains and hemoglobin Bart’s using immunochromatographic strip tests for α0-thalassemia (--SEA) differential diagnosis
- Cognitive impairment and medication adherence post-stroke: A five-year follow-up of the ASPIRE-S cohort
- Correction: Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism
- Correction: Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana
- Correction: Precision public health: Mapping socioeconomic disparities in opioid dispensations at Swedish pharmacies by Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA)
- Epidemiological, clinical and laboratory characteristics of the measles resurgence in the Republic of Serbia in 2014-2015
- Macro-charcoal accumulation in floodplain wetlands: Problems and prospects for reconstruction of fire regimes and environmental conditions
- Stage at diagnosis and stage-specific survival of breast cancer in Latin America and the Caribbean: A systematic review and meta-analysis
- Correction: Retraction: Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway
- TEM8/ANTXR1-specific CAR T cells mediate toxicity in vivo
- Clinical impact of intraoperative hyperlactatemia during craniotomy
- Intubation with channeled versus non-channeled video laryngoscopes in simulated difficult airway by junior doctors in an out-of-hospital setting: A crossover manikin study
- Age and growth of stocked juvenile Shoal Bass in a tailwater: Environmental variation and accuracy of daily age estimates
- Sex-specific differences in risk factors of lymph node metastasis in patients with early gastric cancer
- The impact of electroconvulsive therapy on the spatial QRS-T angle and cardiac troponin T concentration in psychiatric patients
- BDNF, NT-3 and Trk receptor agonist monoclonal antibodies promote neuron survival, neurite extension, and synapse restoration in rat cochlea ex vivo models relevant for hidden hearing loss
- Investigation on the hereditary basis of colorectal cancers in an African population with frequent early onset cases
- Comparison of cancer prevalence between patients with glomerulonephritis and the general population at the time of kidney biopsy
- Predictors of time to unfavorable treatment outcomes among patients with multidrug resistant tuberculosis in Oromia region, Ethiopia
- Experimentally validated simulation of coronary stents considering different dogboning ratios and asymmetric stent positioning
- The membrane effects of melittin on gastric and colorectal cancer
- Exclusive breastfeeding policy, practice and influences in South Africa, 1980 to 2018: A mixed-methods systematic review
- Hippocampal subfield volumes and pre-clinical Alzheimer’s disease in 408 cognitively normal adults born in 1946
- Uncorrected low hyperopia in young subjects induces postural instability even in those with clear visual acuity
- Membrane associated proteins of two Trichomonas gallinae clones vary with the virulence
- Awareness, current use of electronic cigarettes and associated smoking factors in Zhejiang Chinese adolescents
- Associations between pre-pregnancy BMI, gestational weight gain, and prenatal diet quality in a national sample
- Effects of continuous ketamine infusion on hemodynamics and mortality in critically ill children
- Optofluidic laser speckle image decorrelation analysis for the assessment of red blood cell storage
- Complete chloroplast genome sequence and phylogenetic analysis of Spathiphyllum 'Parrish'
- Strategic science communication as planned behavior: Understanding scientists’ willingness to choose specific tactics
- Understanding spatial patterns of soils for sustainable agriculture in northern Ethiopia’s tropical mountains
- Does Japan’s national nutrient-based dietary guideline improve lifestyle-related disease outcomes? A retrospective observational cross-sectional study
- Agitation near the end of life with dementia: An ethnographic study of care
- Tick-borne encephalitis virus infections in Germany. Seasonality and in-year patterns. A retrospective analysis from 2001-2018
- Encouraging perspective taking: Using narrative writing to induce empathy for others engaging in negative health behaviors
- Considerations of target surface area and the risk of radiosurgical toxicity
- Correction: A comparative study of RNA-Seq and microarray data analysis on the two examples of rectal-cancer patients and Burkitt Lymphoma cells
- Effect of using immobilization device in fluoroscopic study in pediatric patient: Focused on radiation dose reduction in voiding cystourethrogram
- Temporal trends in breast cancer survival by race and ethnicity: A population-based cohort study
- Contamination of hospital surfaces with respiratory pathogens in Bangladesh
- The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-based oxygen carrier: The cold-to-warm machine perfusion of the liver
- Association between hospital interval and survival in patients with oral cancer: A waiting time paradox
- Translating a stress management intervention for rural Latina breast cancer survivors: The Nuevo Amanecer-II
- Comprehensive management of obstructive sleep apnea by telemedicine: Clinical improvement and cost-effectiveness of a Virtual Sleep Unit. A randomized controlled trial
- Proteomic characterisation of the Chlamydia abortus outer membrane complex (COMC) using combined rapid monolithic column liquid chromatography and fast MS/MS scanning
- Harnessing therapeutic viruses as a delivery vehicle for RNA-based therapy
- Korean soybean core collection: Genotypic and phenotypic diversity population structure and genome-wide association study
- Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study
- Measurement of structural integrity of the spinal cord in patients with amyotrophic lateral sclerosis using diffusion tensor magnetic resonance imaging
- Typological analysis of public-private partnerships in the veterinary domain
- Improved clinical outcome after medial open-wedge osteotomy despite cartilage lesions in the lateral compartment
- Rapid and structure-specific cellular uptake of selected steroids
- Avoiding gambling harm: An evidence-based set of safe gambling practices for consumers
- Epidemiology of chronic pain in Ukraine: Findings from the World Mental Health Survey
- PIAS1 is not suitable as a urothelial carcinoma biomarker protein and pharmacological target
- Double triage to identify poorly annotated genes in maize: The missing link in community curation
- N-acetyl cysteine restores the fertility of vitrified–warmed mouse oocytes derived through ultrasuperovulation
- Architecture of population-differentiated polymorphisms in the human genome
- Linguistic neutrosophic power Muirhead mean operators for safety evaluation of mines
- Extracellular vesicles nanoarray technology: Immobilization of individual extracellular vesicles on nanopatterned polyethylene glycol-lipid conjugate brushes
- Exercise intensity-dependent effects of arm and leg-cycling on cognitive performance
- How information about perpetrators’ nature and nurture influences assessments of their character, mental states, and deserved punishment
- Stringent response governs the oxidative stress resistance and virulence of Francisella tularensis
- In silico assessment of human Calprotectin subunits (S100A8/A9) in presence of sodium and calcium ions using Molecular Dynamics simulation approach
- Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging
- Measurable residual disease monitoring for patients with acute myeloid leukemia following hematopoietic cell transplantation using error corrected hybrid capture next generation sequencing
- Characteristics of complementary medicine therapists in Switzerland: A cross-sectional study
- Lack of generalization between explicit and implicit visuomotor learning
- Diet modulates cecum bacterial diversity and physiological phenotypes across the BXD mouse genetic reference population
- Effects of temperature and salinity on respiratory losses and the ratio of photosynthesis to respiration in representative Antarctic phytoplankton species
- Self-reported non-receipt of HIV test results: A silent barrier to HIV epidemic control in Mozambique
- Plasma midkine concentrations in healthy children, children with increased and decreased adiposity, and children with short stature
- Echocardiography overestimates LV mass in the elderly as compared to cardiac CT
- Efficacy of cotrimoxazole (Sulfamethoxazole-Trimethoprim) as a salvage therapy for the treatment of bone and joint infections (BJIs)
- Molecular mechanism of antimicrobial activity of chlorhexidine against carbapenem-resistant Acinetobacter baumannii
- First identification of the benzimidazole resistance-associated F200Y SNP in the beta-tubulin gene in Ascaris lumbricoides
- Green synthesis of silver nanoparticles using Solanum mammosum L. (Solanaceae) fruit extract and their larvicidal activity against Aedes aegypti L. (Diptera: Culicidae)
- Enterovirus 71 seroepidemiology in Taiwan in 2017 and comparison of those rates in 1997, 1999 and 2007
- Effect of statin on life prognosis in Japanese patients undergoing hemodialysis
- 13C and 15N NMR identification of product compound classes from aqueous and solid phase photodegradation of 2,4,6-trinitrotoluene
- Off-target effects of CRISPRa on interleukin-6 expression
- Exploring the antimicrobial properties of dark-operating ceramic-based nanocomposite materials for the disinfection of indoor air
- Experienced males recognise and avoid mating with non-virgin females in the western flower thrips
- Liver transplantation in patients with a history of migration—A German single center comparative analysis
- Retraction: The Different Role of Notch1 and Notch2 in Astrocytic Gliomas
- Correction: Understanding climate change from a global analysis of city analogues
- Comparison of 4D Flow MRI to 2D Flow MRI in the pulmonary arteries in healthy volunteers and patients with pulmonary hypertension
- The relationship between sleep quality, inappropriate medication use and frailty among older adults in aged care homes in Malaysia
- Clonal diversity and spatial genetic structure in the long-lived herb, Prairie trillium
- Medication histories documentation at the community pharmacy setting: A study from Jordan
- Population dynamics of an invasive bird parasite, Philornis downsi (Diptera: Muscidae), in the Galapagos Islands
- Because you had a bad day: General and daily relations between reactive temperament, emotion regulation, and depressive symptoms in youth
- Socioeconomic status and alcohol use disorders across the lifespan: A co-relative control study
- Generation of deletions and precise point mutations in Dictyostelium discoideum using the CRISPR nickase
- Polymorphisms in vasoactive eicosanoid genes of kidney donors affect biopsy scores and clinical outcomes in renal transplantation
- Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma: A preclinical F98 glioblastoma rat model study
- Validation and perception of a key feature problem examination in neurology
- Gender affirmative HIV care framework: Decisions on feminizing hormone therapy (FHT) and antiretroviral therapy (ART) among transgender women
- Quantifying international human mobility patterns using Facebook Network data
- Localization and characterization of thyroid microcalcifications: A histopathological study
- Young children are the main victims of fast food induced obesity in Brazil
- Understanding self-reported importance of religion/spirituality in a North American sample of individuals at risk for familial depression: A principal component analysis
- Standing balance of professional ballet dancers and non-dancers under different conditions
- 30-day unplanned readmission rate in otolaryngology patients: A population-based study in Thuringia, Germany
- Physical exercise stimulates salivary secretion of cystatins
- Vintage electronics for trusted radiation measurements and verified dismantlement of nuclear weapons
- Keepin’ it real: Linguistic models of authenticity judgments for artificially generated rap lyrics
- Carbon emission reduction and profit distribution mechanism of construction supply chain with fairness concern and cap-and-trade
- Modulations of microbehaviour by associative memory strength in Drosophila larvae
- Changes in peak expiratory flow rates using two head-tilt/chin-lift maneuver angles in young healthy conscious volunteers
- 3D image analysis reveals differences of CD30 positive cells and network formation in reactive and malignant human lymphoid tissue (classical Hodgkin Lymphoma)
- Change in larval fish assemblage in a USA east coast estuary estimated from twenty-six years of fixed weekly sampling
- 2-methylquinazoline derivative F7 as a potent and selective HDAC6 inhibitor protected against rhabdomyolysis-induced acute kidney injury
- Correction: Reducing growth and developmental problems in children: Development of an innovative postnatal risk assessment
- Comparative analysis of the vertebral pneumatization in pterosaurs (Reptilia: Pterosauria) and extant birds (Avialae: Neornithes)
- Associations between cognitive performance and sigma power during sleep in children with attention-deficit/hyperactivity disorder, healthy children, and healthy adults
- Retraction: MiR-375 Is Epigenetically Downregulated by HPV-16 E6 Mediated DNMT1 Upregulation and Modulates EMT of Cervical Cancer Cells by Suppressing lncRNA MALAT1
- Comparing growth patterns of three species: Similarities and differences
- Iron is increased in the brains of ageing mice lacking the neurofilament light gene
- Economic evaluation of community acquired pneumonia management strategies: A systematic review of literature
- A participatory community case study of periurban coastal flood vulnerability in southern Ecuador
- Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL
- Mitochondrial dysfunctions in leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL)
- MRI-based visualization of rTMS-induced cortical plasticity in the primary motor cortex
- Knowledge, attitudes, and practices related to anthrax and animal care: A case-control study in Georgia
- Information diffusion in signed networks
- Nurses’ perspectives on their communication with patients in busy oncology wards: A qualitative study
- Inflammation in acute coronary syndrome: Expression of TLR2 mRNA is increased in platelets of patients with ACS
- ART is key to clearing oncogenic HPV genotypes (HR-HPV) in anal mucosa of HIV-positive MSM
- Retraction: Fluid–Structure Interaction-Based Biomechanical Perception Model for Tactile Sensing
- Correction: Role of Caveolin-1 in Atrial Fibrillation as an Anti-Fibrotic Signaling Molecule in Human Atrial Fibroblasts
- The French adaptation and validation of the Partners in Health (PIH) scale among patients with chronic conditions seen in primary care
- Depth inversion with a 3D structure influences brightness perception
- Analysis of group evolution prediction in complex networks
- Effect of aridity and dune type on rhizosphere soil bacterial communities of Caragana microphylla in desert regions of northern China
- Knowledge, attitudes, and practices related to TB among the general population of Ethiopia: Findings from a national cross-sectional survey
- Correction: Personality traits in companion dogs—Results from the VIDOPET
- MANET 3.0: Hierarchy and modularity in evolving metabolic networks
- Agreement study on gait assessment using a video-assisted rating method in patients with idiopathic normal-pressure hydrocephalus
- Single fixed low-dose rituximab as induction therapy suppresses de novo donor-specific anti-HLA antibody production in ABO compatible living kidney transplant recipients
- Myomesin is part of an integrity pathway that responds to sarcomere damage and disease
- Acute normobaric hypoxia does not affect the simultaneous exercise-induced increase in circulating BDNF and GDNF in young healthy men: A feasibility study
- Systematic investigation on quad-metallic AgAuPdPt and tri-metallic AuPdPt NPs through the solid-state dewetting of quad-layer Ag/Au/Pd/Pt thin films on c-plane sapphire
- Video lecturing in Clicker-assisted English flipped class
- Significant changes of the choroid in patients with ocular ischemic syndrome and symptomatic carotid artery stenosis
- Skewed T cell responses to Epstein-Barr virus in long-term asymptomatic kidney transplant recipients
- Candidate genes expression profiling during wilting in chickpea caused by Fusarium oxysporum f. sp. ciceris race 5
- Host plants influence the composition of the gut bacteria in Henosepilachna vigintioctopunctata
- ‘We are all serving the same Ugandans’: A nationwide mixed-methods evaluation of private sector surgical capacity in Uganda
- The association between flavor capsule cigarette use and sociodemographic variables: Evidence from Chile
- Relations between gross motor skills and executive functions, controlling for the role of information processing and lapses of attention in 8-10 year old children
- Linalool acts as a fast and reversible anesthetic in Hydra
- Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka
- Using isotemporal substitution to predict the effects of changing physical behaviour on older adults’ cardio-metabolic profiles
- Adherence to general medical checkup and cancer screening guidelines according to self-reported smoking status: Korea National Health and Nutrition Examination Survey (KNHANES) 2010–2012
- Do older English adults exhibit day-to-day compensation in sedentary time and in prolonged sedentary bouts? An EPIC-Norfolk cohort analysis
- Linoleic acid supplementation of cell culture media influences the phospholipid and lipid profiles of human reconstructed adipose tissue
- Correction: Factors associated with hospitalization and death among TB/HIV co-infected persons in Porto Alegre, Brazil
- An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
- Reporting adverse events related to medical devices: A single center experience from a tertiary academic hospital
- Enterohemorrhagic Escherichia coli infection inhibits colonic thiamin pyrophosphate uptake via transcriptional mechanism
- Estimating biodiversity changes in the Camargue wetlands: An expert knowledge approach
- Decreased risk of Parkinson’s disease in diabetic patients with thiazolidinediones therapy: An exploratory meta-analysis
- Retraction: Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis
- Lipoarabinomannan from Mycobacterium indicus pranii shows immunostimulatory activity and induces autophagy in macrophages
- A measure of inconsistencies in intertemporal choice
- A novel radiopaque tissue marker for soft tissue localization and in vivo length and area measurements
- Anatomical, histological and computed tomography comparisons of the eye and adnexa of crab-eating fox (Cerdocyon thous) to domestic dogs
- Subpopulation augmentation among habitat patches as a tool to manage an endangered Mojave Desert wetlands-dependent rodent during anthropogenic restricted water climate regimes
- Characteristics of CD5-positive diffuse large B-cell lymphoma among Koreans: High incidence of BCL2 and MYC double-expressors
- Fossil tabulate corals reveal outcrops of Paleozoic sandstones in the Atlantic Coastal Plain Province, Southeastern USA
- Coming and going – Historical distributions of the European oyster Ostrea edulis Linnaeus, 1758 and the introduced slipper limpet Crepidula fornicata Linnaeus, 1758 in the North Sea
- Behavioral predictors of subsequent respiratory illness signs in dogs admitted to an animal shelter
- Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation
- Can emotional intelligence be improved? A randomized experimental study of a business-oriented EI training program for senior managers
- Genetic variability in landraces populations and the risk to lose genetic variation. The example of landrace ‘Kyperounda’ and its implications for ex situ conservation
- Sleep problems are a strong predictor of stress-related metabolic changes in police officers. A prospective study
- Age, sex and primary care setting differences in patients’ perception of community healthcare seeking behaviour towards health services
- Kinematic analyses including finite helical axes of drop jump landings demonstrate decreased knee control long after anterior cruciate ligament injury
- Effects of model inaccuracies on reaching movements with intermittent control
- C-reactive protein to albumin ratio predicts the outcome in renal cell carcinoma: A meta-analysis
- A new synthetic lure for management of the invasive giant African snail, Lissachatina fulica
- Bridging solvent molecules mediate RNase A – Ligand binding
- Variation in methods, results and reporting in electronic health record-based studies evaluating routine care in gout: A systematic review
- The use of prophylactic intra-aortic balloon pump in high-risk patients undergoing coronary artery bypass grafting
- Compliance with clinical guidelines for breast cancer management: A population-based study of quality-of-care indicators in France
- Dysregulated T helper type 1 (Th1) and Th17 responses in elderly hospitalised patients with infection and sepsis
- Acute effects of differential learning on football kicking performance and in countermovement jump
- Escherichia coli and Salmonella spp. isolated from Australian meat chickens remain susceptible to critically important antimicrobial agents
- Play like me: Similarity in playfulness promotes social play
- Awareness of family health history in a predominantly young adult population
- Care pathways during a child’s final illness in rural South Africa: Findings from a social autopsy study
- Intranasal lidocaine for acute migraine: A meta-analysis of randomized controlled trials
- Evaluating case management as a complex intervention: Lessons for the future
- Allele-specific enhancer interaction at the Peg3 imprinted domain
- Has the “M” word been framed? Marijuana, cannabis, and public opinion
- Is spontaneous normalization of systolic blood pressure within 24 hours after ischemic stroke onset related with favorable outcomes?
- Mixotrophic cultivation of Spirulina platensis in dairy wastewater: Effects on the production of biomass, biochemical composition and antioxidant capacity
- Constitutive expression of an A-5 subgroup member in the DREB transcription factor subfamily from Ammopiptanthus mongolicus enhanced abiotic stress tolerance and anthocyanin accumulation in transgenic Arabidopsis
- Stable carbon isotope diagnostics of mammalian metabolism, a high-resolution isotomics approach using amino acid carboxyl groups
- Factors associated with depressive symptoms in patients with ankylosing spondylitis in Northern Taiwan
- A multicenter prospective study of 515 febrile neutropenia episodes in Argentina during a 5-year period
- Retraction: Reversal Effect of ST6GAL 1 on Multidrug Resistance in Human Leukemia by Regulating the PI3K/Akt Pathway and the Expression of P-gp and MRP1
- Potential role for microRNA-16 (miR-16) and microRNA-93 (miR-93) in diagnosis and prediction of disease progression in mycosis fungoides in Egyptian patients
- Rapid visual categorization is not guided by early salience-based selection
- Relative contribution of climate and non-climate drivers in determining dynamic rates of boreal birds at the edge of their range
- A simple-to-use nomogram to predict long term survival of patients undergoing coronary artery bypass grafting (CABG) using bilateral internal thoracic artery grafting technique
- Effects of sonication parameters on transcranial focused ultrasound brain stimulation in an ovine model
- Antenatal and intrapartum interventions for reducing caesarean section, promoting vaginal birth, and reducing fear of childbirth: An overview of systematic reviews
- Relative species abundance successfully predicts nestedness and interaction frequency of monthly pollination networks in an alpine meadow
- Correction: RCER: Reliable Cluster-based Energy-aware Routing protocol for heterogeneous Wireless Sensor Networks
- Amphibians on the hotspot: Molecular biology and conservation in the South American Atlantic Rainforest
- Role of psychosocial status in predicting health-related quality of life at 1-year follow-up among newly diagnosed people living with HIV
- Application of national pollutant inventories for monitoring trends on dioxin emissions from stationary industrial sources in Australia, Canada and European Union
- The association between vaccination confidence, vaccination behavior, and willingness to recommend vaccines among Finnish healthcare workers
- Retraction: Interleukin-1β-Induced Autophagy-Related Gene 5 Regulates Proliferation of Embryonic Stem Cell-Derived Odontoblastic Cells
- A localized sanitation status index as a proxy for fecal contamination in urban Maputo, Mozambique
- E2 protein is the major determinant of specificity at the human papillomavirus origin of replication
- “You’re kind of at war with yourself as a nurse”: Perspectives of inpatient nurses on treating people who present with a comorbid opioid use disorder
- A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury
- Circulating cell-free DNA from plasma undergoes less fragmentation during bisulfite treatment than genomic DNA due to low molecular weight
- Understanding fatigue in adults with visual impairment: A path analysis study of sociodemographic, psychological and health-related factors
- Retraction: Mouse-Induced Pluripotent Stem Cells Differentiate into Odontoblast-Like Cells with Induction of Altered Adhesive and Migratory Phenotype of Integrin
- A novel analytical method to assess the effect of imipenem/cilastatin on liver function laboratory indexes in Chinese underage inpatients: Probability distribution curve
- The cause of anorexia and proportion of its recovery in older adults without underlying disease: Results of a retrospective study
- Referral and admission to intensive care: A qualitative study of doctors’ practices in a Tanzanian university hospital
- Agreement between clinical and non-clinical digital manometer for assessing maximal respiratory pressures in healthy subjects
- Heads or tails? Differential translational regulation in cercarial heads and tails of schistosome worms
- Horizontal seed dispersal by dung beetles reduced seed and seedling clumping, but did not increase short-term seedling establishment
- The coupling of the M2 muscarinic receptor to its G protein is voltage dependent
- Subsidy strategy of pharmaceutical e-commerce platform based on two-sided market theory
- Shoulder girdle injuries involving the medial clavicle differ from lateral clavicle injuries with a focus on concomitant injuries and management strategies: A retrospective study based on nationwide routine data
- Unraveling middle childhood attachment-related behavior sequences using a micro-coding approach
- Divergence history and hydrothermal vent adaptation of decapod crustaceans: A mitogenomic perspective
- Duration of solid fuel cookstove use is associated with increased risk of acute lower respiratory infection among children under six months in rural central India
- Evolving flocking in embodied agents based on local and global application of Reynolds’ rules
- Non-invasive contrast enhanced ultrasound molecular imaging of inflammation in autoimmune myocarditis for prediction of left ventricular fibrosis and remodeling
- Care coordination for chronic and complex health conditions: An experienced based co-design study engaging consumer and clinician groups for service improvement
- Association between socioeconomic status and diet quality in Mexican men and women: A cross-sectional study
- Surveillance of panicle positions by unmanned aerial vehicle to reveal morphological features of rice
- Is Betula carpatica genetically distinctive? A morphometric, cytometric and molecular study of birches in the Bohemian Massif with a focus on Carpathian birch
- Correction: Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance
- The genome of the migratory nematode, Radopholus similis, reveals signatures of close association to the sedentary cyst nematodes
- Factors associated with pneumococcal carriage and density in infants and young children in Laos PDR
- Overlap between telangiectasia and photoreceptor loss increases with progression of macular telangiectasia type 2
- The role of hope for health professionals in rehabilitation: A qualitative study on unfavorable prognosis communication
- Expression of miR-34a-5p is up-regulated in human colorectal cancer and correlates with survival and clock gene PER2 expression
- Molecular characterization and In Vitro synthesis of infectious RNA of a Turnip vein-clearing virus isolated from Alliaria petiolata in Hungary
- Assessment of client satisfaction with pharmacist services at outpatient pharmacy of Tikur Anbessa Specialized Hospital
- Thermogravimetric analysis of the co-combustion of coal and polyvinyl chloride
- Roles of leptin in the recovery of muscle and bone by reloading after mechanical unloading in high fat diet-fed obese mice
- Unexpected high seroprevalence of hepatitis E virus in patients with alcohol-related cirrhosis
- APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy
- Integrating a gait analysis test in hospital rehabilitation: A service design approach
- Correction: Bioactivity-guided isolation of rosmarinic acid as the principle bioactive compound from the butanol extract of Isodon rugosus against the pea aphid, Acyrthosiphon pisum
- Soil-borne fungi influence seed germination and mortality, with implications for coexistence of desert winter annual plants
- Applying Corrigan’s progressive model of self-stigma to people with depression
- Do psychosocial factors modify the negative association between disability and life satisfaction in old age?
- Public perception of coastal habitat loss and habitat creation using artificial floating islands in the UK
- Transcriptional foliar profile of the C3-CAM bromeliad Guzmania monostachia
- Application of tuned liquid column ball damper (TLCBD) for improved vibration control performance of multi-storey structure
- Do protection gradients explain patterns in herbivore densities? An example with ungulates in Zambia’s Luangwa Valley
- Consequences of chronic bacterial infection in Drosophila melanogaster
- The effects of environmental parameters on the microbial activity in peat-bog lakes
- Differences in protein structural regions that impact functional specificity in GT2 family β-glucan synthases
- Correction: Identification of lysine methylation in the core GTPase domain by GoMADScan
- Changes of absorbed dose rate in air in metropolitan Tokyo relating to radiocesium released from the Fukushima Daiichi Nuclear Power Plant accident: Results of a five-year study
- Histological chorioamnionitis, antenatal steroids, and neonatal outcomes in very low birth weight infants: A nationwide study
- A machine learning approach for the prediction of pulmonary hypertension
- Altered microbiota, fecal lactate, and fecal bile acids in dogs with gastrointestinal disease
- Impaired processing of threat in psychopathy: A systematic review and meta-analysis of factorial data in male offender populations
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- Retraction: Sialoglycosylation of RBC in Visceral Leishmaniasis Leads to Enhanced Oxidative Stress, Calpain-Induced Fragmentation of Spectrin and Hemolysis
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- Correction: Stillbirths in urban Guinea-Bissau: A hospital- and community-based study
- Correction: Method for spike detection from microelectrode array recordings contaminated by artifacts of simultaneous two-photon imaging
- Correction: Peripheral blood mononuclear cells extracts VEGF protein levels and VEGF mRNA: Associations with inflammatory molecules in a healthy population
- Correction: Novel site-specific PEGylated L-asparaginase
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- Correction: Color adaptation induced from linguistic description of color
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- Correction: Relationship between non-communicable diseases and background characteristics among homeless people in Nagoya City, Japan
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- Correction: Forecasting the impact of population ageing on tuberculosis incidence
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- Correction: Multilevel analyses of on-demand medication data, with an application to the treatment of Female Sexual Interest/Arousal Disorder
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- Correction: Predictors of opioid efficacy in patients with chronic pain: A prospective multicenter observational cohort study
- Correction: Comparative prognostic accuracy of sepsis scores for hospital mortality in adults with suspected infection in non-ICU and ICU at an academic public hospital
- Correction: Biosynthesis of the oxygenated diterpene nezukol in the medicinal plant Isodon rubescens is catalyzed by a pair of diterpene synthases
- Correction: Effect of early measles vaccine on pneumococcal colonization: A randomized trial from Guinea-Bissau
- Correction: Tuberculosis patients in an Indian mega-city: Where do they live and where are they diagnosed?
- Correction: Priority Queue Based Reactive Buffer Management Policy for Delay Tolerant Network under City Based Environments
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- Correction: Evolution and study of a copycat effect in intimate partner homicides: A lesson from Spanish femicides
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- Correction: Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression
- Correction: Factors influencing the behaviour and perceptions of Australian veterinarians towards antibiotic use and antimicrobial resistance
- Correction: Nonalcoholic fatty liver disease is a risk factor for large-for-gestational-age birthweight
- Retraction: Butyrate Attenuates Lipopolysaccharide-Induced Inflammation in Intestinal Cells and Crohn's Mucosa through Modulation of Antioxidant Defense Machinery
- Retraction: Tetrandrine Suppresses Lipopolysaccharide-Induced Microglial Activation by Inhibiting NF-κB and ERK Signaling Pathways in BV2 Cells
- Correction: Isolation of five Enterobacteriaceae species harbouring blaNDM-1 and mcr-1 plasmids from a single paediatric patient
- Correction: Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents
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