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ReklamaThe pragmatic role of trust in young children’s interpretation of unfamiliar signals
Authors: Olivier Mascaro aff001; Dan Sperber aff002
Authors place of work: Institute for Cognitive Sciences, CNRS UMR5304/Lyon 1 University, Bron, France aff001; Social Mind Center, Central European University, Budapest, Hungary aff002
Published in the journal: PLoS ONE 14(10)
Category: Research Article
doi: https://doi.org/10.1371/journal.pone.0224648Summary
What role does children’s trust in communication play in their acquisition of new meanings? To answer, we report two experimental studies (N = 81) testing how three - to four-year-olds interpret the meaning of a novel communicative device when it is used by a malevolent and potentially deceptive informant. Children participated in a hiding game in which they had to find a reward hidden in one of two boxes. In the initial phase of the experiments, a malevolent informant always indicated the location of the empty box using a novel communicative device, either a marker (Study 1), or an arrow (Study 2). During that phase, 3 - and 4-year-olds learned to avoid the box indicated by the novel communicative device. In the second phase of the test, the malevolent informant was replaced by a benevolent one. Nevertheless, children did not change their search strategy, and they kept avoiding the box tagged by the novel communicative device as often as when it had been produced by the malevolent informant. These results suggest that during the initial phase, children (i) did not consider the possibility that the malevolent informant might intend to deceive them, and (ii) did not ignore the unfamiliar communicative signal or treat it as irrelevant. Instead, children relied on the unfamiliar communicative signal to locate the empty box’s location. These results suggest that children’s avoidance of the location indicated by an unfamiliar signal is not unambiguous evidence for distrust of such signal. We argue that children’s trust in ostensive communication is likely to extend to unfamiliar communicative means, and that this presumption of trustworthiness plays a central role in children’s acquisition of new meanings.
Keywords:
Learning – Communications – Social communication – Behavior – children – Frogs – Communication equipment – Speech signal processing
Introduction
As David Lewis [1] among others argued, epistemic trust plays a crucial role in the acquisition of word meaning. If your interlocutor says, pointing to a flower you don’t know, “look at this gorgeous sobralia”, you might infer that the word “sobralia” refers to a kind of flower of which this is an exemplar. This pragmatic inference is only justified, however, if you trust your interlocutor to speak competently and honestly. Children, who acquire new words every day, must similarly trust their interlocutors to speak truly in order to infer the meaning of these words (and more generally of forms of communication they are not familiar with). Here we test how young children’s inferences about the meaning of a new non-verbal signal might be influenced by trust.
Philosophers and psychologists agree with common wisdom that young children are trusting [2–3]. But how trusting are they? If they were gullible to the point of unconditionally believing whatever they are told, they should remain helpless and dumbfounded when two informants provide incompatible testimonies. Recent work in developmental psychology has shown that such is not the case. When given conflicting testimonies by two informants, children trust more an informant who has been accurate before, is more confident, has better access to information, or is more benevolent [3–7]. Other studies have shown that children can disbelieve communicated information that conflicts with what they perceive or remember [8–10].
So, children are not trusting to the point of being wholly unable to choose among two conflicting sources of information. But what happens when there is a single informant whose testimony does not contradict the child’s own beliefs? In such a case, do children always trust the testimony or are they capable, as adults are, to sometimes disbelieve or just ignore it? What happens in particular if children are given strong evidence that the informant may be providing them with false information? In previous studies, it was found that three-year-olds (but not four-year-olds) told that an informant always lies nonetheless accepted his or her testimony, and that four-year-olds (but not five-year-old) told that an informant did not want to help them did likewise [11]. It has also been found that despite their capacity to treat the utterance of a single speaker as false [12], young pre-schoolers tend to persevere in trusting a single informant who has repeatedly misled them [11, 13–15].
Children are trusting to the point of failing to take into account repeated evidence that an informant is untrustworthy and likely to deceive them. Why? One hypothesis is that children understand communication as a helpful behavior [13, 16]. As argued by Grice [17] or Sperber and Wilson [18], by the very act of communicating, communicators present themselves as benevolent and competent, willing and able to provide true and relevant information to their audience. The very fact of being addressed by a communicator elicits in the audience an initial ‘stance of trust’ [19] that may be stronger in younger children. Actually, the acquisition of cultural knowledge would not be possible if children were unwilling to pay attention to and to take a trusting attitude towards forms of communication with which they have little or no familiarity.
Children learn words that they have never encountered before and they do so on the basis of little exposure [20–21]. These words are comprehended and used before becoming familiar. Similarly, children learn from demonstrations about unknown objects, which often involve a set of unfamiliar demonstration gestures. When engaging in this kind of learning, children display trust in what is conveyed to them by means of an unfamiliar communicative action [22–23]. Overall the data thus suggest that children have a general tendency to trust communication (or more specifically ‘ostensive communication’; see [24]) whoever communicates and whatever means of communication are being used.
According to a second (not mutually exclusive) hypothesis, young children are disposed to believe what is communicated to them because of a more specific trust in signals that they have repeatedly experienced to be reliable in the past (for discussions see [14, 25]). For example, in Palmquist, Burns, and Jaswal [26], three-year-old children saw one informant hide a sticker and another fail to pay attention. Then both informants indicated where they thought the sticker was, either by pointing or by using an unfamiliar signal. When both informants pointed, children didn’t trust one more than the other. When, on the other hand, both informants used unfamiliar signals, then children chose the location indicated by the more knowledgeable informant. One interpretation of these results is that the high level of trust elicited by familiar signals, such as pointing, can disrupt children’s capacity to track informants’ knowledge.
In short, when children are addressed by a single informant who uses familiar communicative means such as pointing or verbal testimony, they seem to be spontaneously trustful. The lack of vigilance that children evidence in these situations may have two sources: (i) a general disposition to treat communicated information as reliable (regardless of the communicative means employed), and (ii) a more specific disposition to treat as reliable signals that have proven to be reliable in the past.
Two studies, one by Couillard and Woodward [27], and one by Jaswal, Croft, Setia, and Cole [14] provide relevant evidence to test these two hypotheses. In Couillard and Woodward [27], preschoolers had to find a sticker hidden under one of two upside-down bowls. The experimenter misleadingly indicated the empty bowl either by pointing toward it or by placing a marker on it. Over the course of 10 trials, 3-year-olds were more likely to persevere and search under the empty bowl when the experimenter pointed to it than when she placed a marker on it. Similarly, in Jaswal et al., [14] 3-year-olds either heard an experimenter claim that a sticker was in one location when it was actually in another one, or they saw her place an arrow on the empty location. In both conditions, children initially tended to search the wrong location, but then those who were hearing the deceptive verbal testimony persevered, whereas those who saw the incorrect location being marked with an arrow quickly learned to search in the correct location. On the face of it, these results could be interpreted as evidence that when a misleading informant uses unfamiliar communicative means, young preschoolers are less trusting than when the misleading informant uses a familiar communicative means.
These results are, however, open to an alternative interpretation. When an informant’s communicative behavior has misled you, you might either withdraw your trust in the informant or still trust the informant but revise your interpretation of the signal. As the evidence shows, when the signal used—pointing or speech—is familiar, 3-year-olds do not learn anything from being repeatedly misled. They neither withdraw their trust nor reinterpret the signal. On the other hand, when the informant uses an unfamiliar signal, children do seem to learn. What do they learn? There are two possibilities 1) They might learn that the communicator is misinforming them and withdraw their trust; 2) they might maintain their trust and use this trust as a premise in inferring that the signal indicates not where the reward is, but where it is not.
We report two experimental studies that compare these two hypotheses. Three - and four-year-olds participated in a task in which they had to find an object hidden in one of two boxes. They were provided information by means of an unfamiliar signal, i.e. by the placement of a marker on one of the two boxes in Study 1, following [27–28], and by an arrow in Study 2, following [14].
During the initial phase of the study, a first informant, who was explicitly said to be mean and uncooperative, always indicated the empty box with the unfamiliar communicative device (i.e., placing the marker on the empty box, or pointing towards it with the arrow). We hypothesized that during this first phase, children would learn to avoid the location indicated by the unfamiliar communicative device (just like children had done in [14; 27]). In the second phase of the study, the mean informant was replaced by a different informant who was said to be nice and willing to help the children. This second phase was intended to provide evidence of the inferences children had drawn in the first phase of the study (where a first “mean” informant had repeatedly indicated the empty box with the unfamiliar communicative device).
A first possibility is that children had interpreted the unfamiliar communicative device as meaning that the box that it indicated contained the hidden object and, given that this box turned out one trial after the other to be empty, had learned to mistrust the malevolent informant and to look for the object in the other box. If this first hypothesis is correct, children should revise their strategy in the second phase of the experiment: being told that the second informant using the unfamiliar communicative device is benevolent, they should then look for the object in the box indicated by the unfamiliar communicative device.
Alternatively, children may have kept trusting the first informant even though they were told he was mean. They may then have learned to avoid the box indicated by the unfamiliar communicative device, not because of distrust, but because they revised their initial interpretation and inferred that what the unfamiliar communicative device meant was that the box that it indicated was empty. If this second hypothesis is correct, children who had trusted the first informant described as “mean” should a fortiori trust the second informant described as “nice” and should continue to avoid the box indicated by the unfamiliar communicative device.
We also tested a different group of children in a baseline trust condition in order to make sure that the initial phase in which the informant was "mean" played a role in guiding children's interpretation of the unfamiliar communicative device's meaning. This baseline trust condition was identical to the test condition except that it only included the second phase of the experiment, in which the informant was characterized as nice and willing to help.
Study 1
Methods
Ethics statement
This research was approved by the institutional review board of the doctoral school ED3C (Ecole Normale Supérieure, Ecole des Hautes Etudes en Sciences Sociales, University Paris VI) and by the regional board of schools (Inspection Académique du Tarn). It was conducted in accordance with the ethical guidelines of the French National Research Center (CNRS). The participants’ parents provided written informed consent.
Participants
Three - to four-year-olds (n = 25; M = 4;1, range 3;1 to 4;11) were enrolled in the test condition. An additional group of children participated in the baseline trust condition (n = 12, M = 4;0, range 3;0 to 4;9). Six additional subjects were tested but excluded from data analysis because they failed to answer control questions more than three times (ages 3;2 and 3;3) or because they became fussy or uncooperative (ages 3;1, 3;5, 4;0 and 4;5). In Studies 1 and 2, no data on the ethnic origins of children were collected. In each school, all children of the target age group whose parents gave informed consent were tested, thus explaining sample size variations across age groups. The resulting sample sizes were comparable to those of similar previous studies [14, 27].
Settings and materials
Children were tested in their school, in a quiet room adjacent to their classroom. In all studies, the experimenter faced the child across a small table. Two boxes of different colors were placed at the center of the table, at equal distance of the participant. All the boxes were opaque and had lids, so that the child could not see what was in the boxes once they were closed. In each trial, a reward (a woolen pompom) was hidden in one of the boxes. To prevent carry-over effects, a different pair of boxes was used for each trial. Two different animal puppets (a cow and a frog) were used as informants. Puppets were named using the noun referring to their species (e.g. the frog puppet was referred to as ‘‘the frog”). Puppets used a marker (a 4x4cm white paper square) in order to communicate. The marker was referred to as ‘‘the piece of paper”.
Test condition
Before the experiment started, the experimenter showed the boxes, the pompom and the puppets to the participant. He also explained that he was going to hide the pompom in one of the two boxes and that the aim of the game was to find out where the pompom was. At the beginning of each trial, the experimenter opened the boxes and he asked the participant to turn round. He placed the pompom in one of the boxes, before closing them loudly. The child was then invited to look again with the remark: ‘‘That’s it! I have hidden the pompom!”. Whether the pompom was hidden in the box located on the right or left side of the table was randomized across trials. Similarly, for each pair of boxes, the box in which the pompom was placed was randomized across trials. For each trial, the puppet that acted as an informant was placed at the center of the table, behind the boxes.
Mean informant trials. The first phase of the test condition consisted of ten trials where the puppet that acted as an informant was described as “mean”. Each trial started with a characterization phase, that ensured that participants encoded information about the puppet’s meanness and lack of cooperativeness. During this initial characterization phase, the experimenter said: “Pay attention, the [name of the puppet, e.g. frog] is mean! It does not want you to find the pompom”. The experimenter then asked two control questions while pointing towards the puppet that acted as an informant: “Is it mean?” (control question 1) and: “Does it want you to find the pompom?” (control question 2). Children were corrected each time they failed to answer a control question. We excluded from the data analysis participants who failed to answer control questions appropriately more than three times during the experiment.
Once the child had answered the control questions, the experimenter explained: “Now the [name of the puppet, e.g. frog] is going to do something”. The experimenter manipulated the puppet so that it seemed to lift the marker before placing it on one of the boxes. The puppet that was said to be “mean” always placed the marker on the empty box. The experimenter then asked the test question: “Where is the pompom?”. The participants could answer the test question verbally or by pointing. At the end of the first trial, children received no information about the real location of the pompom. The experimenter simply said: “Let’s play again!” before swapping the boxes used during the first trial with a new pair of boxes. Children thus first participated in two “pre-training trials” with the mean puppet before receiving any feedback. We decided to have two pre-training trials in our Study (instead of one) in order to have more data about the behavior of participants before they received any feedback. From the end of the second trial on and for the eight subsequent trials, the experimenter gave feedback to the child by opening the boxes at the end of each trial, revealing the location of the pompom. The marker and the pompom were then placed at the center of the table, and memory prompts were given to the child: “Where was the pompom?” (memory prompt 1) “And where was the piece of paper?” (memory prompt 2). We assessed participants’ performance during the two first mean informant trials (pre-training trials); and during the two last mean informant trials (post-training trials). After the tenth mean informant trial, the experimenter said: “Now we are going to play with another animal!”. He replaced the “mean” puppet with a new one (e.g. a cow), and the nice informant trials started.
Nice informant trials. The second phase of the experiment consisted of two trials where the puppet that acted as an informant was described as “nice.” The trials involving the nice puppet unfolded just as the trials involving the mean puppet, with two exceptions. First, during the characterization phase occurring at the beginning of each trial, the experimenter conveyed that the puppet was benevolent and helpful by saying: “Pay attention, the [name of the puppet, e.g. cow] is nice! It wants you to find the pompom.” The control questions that followed were the same as in the mean informant trials (control question 1: “Is it mean?”; control question 2: “Does it want you to find the pompom?”). Second, children received no feedback about the actual location of the pompom at the end of each of the two nice informant trials. The type of puppet used to impersonate the “mean” or the “nice” informant—frog or cow—was randomized across subjects.
Baseline trust condition
The baseline trust condition was identical to the test condition, except that children did not participate in trials involving the “mean” puppet. Participants enrolled in this condition only participated in the presentation of the game, directly followed by two nice informant trials whose procedure was the same as in the test condition.
Scoring and data analysis
Data were coded online by the experimenter (as in previous studies using similar tasks [11, 13–14, 27–30]. In the test condition, the children’s performances were assessed at three stages: during the pre-training trials (the first two mean informant trials), that occurred before children received feedback about the location of the reward; during the post-training trials, i.e., on the last two mean informant trials (the ninth and the tenth trials); and during the nice informant trials that occurred at the very end of the procedure of the test condition. Statistics were computed over the percentage of trials in which the participants selected the box on which the marker was placed for each stage of the test condition (pre-training, post-training, and nice informant trials), and for the nice informant trials of the baseline condition. All the statistical tests reported in this paper are two-tailed. Given the discontinuous nature of our data, we used only non-parametric statistics.
Results and discussion
Pre-training trials (Mean informant trials 1 and 2). As Fig 1 shows, the average percentage of the pre-training trials in which the participants selected the box on which the marker was placed did not differ significantly from what could be predicted by chance (M = 62%, SD = 38.16, W = 93.5, p = .13, one-sample Wilcoxon signed-rank test). Thus, before the participants received feedback about the location of the reward, they did not systematically avoid the box on which the marker was placed.
Fig. 1. Average percentage of trials in which children selected the box indicated by the marker per phase of the test condition in Study 1 (SEM) (*: p < .05, **: p < .01, ***: p < .001). Post-training trials (Mean informant trials 9 and 10). In contrast, the average percentage of the post-training trials in which participants selected the box indicated by the marker was significantly lower from what could be predicted by chance (M = 16%, SD = 33.82, W = 36, p < .001, one-sample Wilcoxon signed-rank test). The participants were significantly less likely to select the box indicated by the marker during the post-training trials than during the pre-training trials (W = 166, p < .001, Wilcoxon signed-rank test for matched pairs). Thus, receiving feedback about the real location of the reward increased the participants’ tendency to avoid the box indicated by the marker.
Nice Informant Trials (Trials 11 and 12). The average percentage of the nice informant trials in which the participants selected the box indicated by the marker was significantly lower from what could be predicted by chance (M = 20%, SD = 34.64, W = 33, p = .001, one-sample Wilcoxon signed-rank test). The participants did not select the box indicated by the marker significantly more often during the nice informant trials than during the post-training mean informant trials (W = 17.5, p = .588, Wilcoxon signed-rank test for matched pairs). Subsequently, in the test condition, participants continued to avoid the box on which the marker was placed even when the malevolent informant was replaced by a benevolent one.
Baseline trust condition
In the baseline trust condition, the participants did not select the box indicated by the marker more often than predicted by chance (M = 62.5%, SD = 36.08, W = 20, p = .25, one-sample Wilcoxon signed-rank test). The participants’ tendency to select the box indicated by the marker was not significantly higher in the baseline trust condition than in the pre-training trials of the test condition (U = 150, p = .98, Mann-Whitney U test). In contrast, the participants were significantly more likely to select the box indicated by the marker in the baseline trust condition than during the post-training trials of the test condition (U = 242.5, p = .003, Mann-Whitney U test), or during the nice informant trials of the test condition (U = 235.5, p = .006, Mann-Whitney U test).
In order to focus on the role of learning on performance, we re-analyzed separately the performance of the participants enrolled in the test condition who selected the box indicated by the mean informant less often during the post-training trials than during the pre-training trials. This selection procedure allowed us to focus on the “learners”, i.e., on the participants who benefitted from receiving feedback about the real location of the reward (n = 17). The average percentage of the pre-training trials in which the learners selected the box indicated by the marker was significantly higher than predicted by chance (M = 79.41%, SD = 24.61, W = 55, p = .002, one-sample Wilcoxon signed-rank test). In contrast, the average percentage of the post-training trials in which the learners selected the box indicated by the marker was significantly lower than predicted by chance (M = 5.88%, SD = 16.11, W = 0, p < .001, one-sample Wilcoxon signed-rank test). The average percentage of the nice informant trials in which the learners selected the box indicated by the marker was significantly lower than predicted by chance (M = 17.65%, SD = 34.05, W = 16, p = .004, one-sample Wilcoxon signed-rank test). The learners did not select the box indicated by the marker significantly more often during the nice informant trials than during post-training trials (W = 12.5, p = .20, Wilcoxon signed-rank test for matched pairs). In addition, the learners’ tendency to select the box indicated by the marker was significantly higher in the baseline trust condition than during the nice informant trials of the test condition (U = 163, p = .007, Mann-Whitney U test). In short, the analyses performed on the subgroup of “learners” confirmed the analyses performed on the whole group of participants.
In the test condition of Study 1, participants learned to avoid the box on which a mean informant placed a marker. Yet, they did not revise this strategy when subsequently, a nice informant used the marker. Still, in Study 1, participants had to discover the function of the marker (communicative) and its meaning (indicating the location of the pompom). The fact that some children misinterpreted the function or the meaning of the marker may be a mere result of its high ambiguity. Indeed, the fact that children did not follow the marker more often than predicted by chance in the baseline condition opens the possibility that the participants may have found it difficult to recognize the communicative nature of the marker. Additionally, the initial phase involving the mean informant was fairly long in Study 1. Maybe some children initially displayed vigilance towards deceptive intents but later engaged in blind avoidance of the marker, for example, because of boredom. To control for these limitations, we designed a second Study with a shorter initial phase involving the mean informant, and in which the informant used a device that was less ambiguous than the marker. In this second Study, the informants communicated using an arrow, i.e. a communicative device whose meaning is conventionalized to some extent. Furthermore, the communicative function of the arrow was demonstrated at the beginning of the Study.
Study 2
Methods
Participants
Three - to four-year-olds (n = 28; M = 4;1, range 3;0 to 4;9) were enrolled in the test condition. An additional group of children participated in the baseline trust condition (n = 16, M = 4;1, range 3;2 to 4;9). Six additional subjects were tested but excluded from data analysis because they failed to answer control questions more than three times (ages 3;0, 3;11 and 4;1) or because they were unresponsive (ages 2;9, 3;0 and 3;0). The recruitment procedure was the same as in Study 1.
Settings and materials
The materials of Study 2 were the same as those of Study 1, except that the informants manipulated a 2D cardboard arrow instead of a marker to communicate the location of the reward. The arrow was laid horizontally on the testing table and it was placed at equidistance of the two boxes that could contain the reward. It was possible to rotate the arrow to point towards one of the boxes.
Test condition
The procedure of the test condition was identical in Study 2 and in Study 1, with the following exceptions. First, the experimenter demonstrated the communicative nature of the arrow at the very beginning of the experiment. After placing two boxes, the arrow and the pompom on the testing table, the experimenter said: “We are going to play a game with two boxes, a pompom, and an arrow.”. Then, the experimenter explained: “With the arrow, I can show a box …”. Next, the experimenter rotated the arrow towards one of the boxes while asking the first prompt question: “Which box am I showing?”. Then, the experimenter rotated the arrow towards the alternate box, while asking the second prompt question: “And now …, which box am I showing?” When participants did not answer appropriately the prompt questions, they were corrected. Second, in Study 2, the mean informant trials and the nice informant trials unfolded exactly as in Study 1 except that the puppets communicated by rotating the arrow towards one of the boxes. Third, children participated in only four consecutive mean informant trials. Children first participated in two pre-training trials in which the mean puppet manipulated the arrow. At the end of the first pre-training trial, children received no feedback about the real location of the pompom. Children thus first participated in the two pre-training trials with the mean puppet before receiving any feedback. From the end of the second trial on and for the two subsequent trials, the experimenter gave feedback to the child by opening the boxes at the end of each trial, revealing the location of the pompom. The arrow and the pompom were then placed at the center of the table, and memory prompts were given to the child: “Where was the pompom?” (memory prompt 1) “And which box did the arrow show?” (memory prompt 2). The mean informant trials ended with the fourth trial (thus, the third and fourth trials were the post-training trials). The transition from the post-training trials (trials 3 and 4) to the nice informant trials (trials 5 and 6) unfolded as in Study 1. The participants were enrolled in two nice informant trials. As in Study 1, the type of puppet used to impersonate the “mean” or the “nice” informant—frog or cow—was randomized across subjects.
Baseline trust condition
As in Study 1, the baseline trust condition was identical to the test condition, except that children did not participate in the trials involving the “mean” puppet. They only participated in the presentation of the game, directly followed two trials that unfolded like the nice informant trials of the test condition.
Scoring and data analysis
As in Study 1, statistics were computed over the percentage of trials in which the participants selected the box indicated by the unfamiliar communicative device (the arrow in Study 2) for each stage of the test condition (pre-training, post-training, and nice informant trials), and for the nice informant trials of the baseline condition.
Results and discussion
Test condition
Pre-training trials (Trials 1 and 2). As Fig 2 shows, in Study 2 the average percentage of the pre-training trials in which the participants selected the box indicated by the arrow was significantly higher than predicted by chance (M = 75%, SD = 41.19, W = 270, p = .006, one-sample Wilcoxon signed-rank test). Furthermore, 26 out of 28 participants kept using the same strategy during the first two trials of the test condition—either selecting the box indicated by the arrow twice or avoiding the box that was indicated by the arrow twice (p < .001, two-choice binomial test). These results reveal that during the pre-training trials, the participants of Study 2 expected to find the reward in the box indicated by the arrow.
Fig. 2. Average percentage of trials in which children selected the box indicated by the arrow per phase of the test condition in Study 2 (SEM) (*: p < .05, **: p < .01, ***: p < .001). Post-training trials (Trials 3 and 4). The average percentage of the post-training trials in which the participants of Study 2 selected the box indicated by the arrow did not differ significantly from what could be predicted by chance (M = 50%, SD = 44.32, W = 126.5, p = 1, one-sample Wilcoxon signed-rank test). As in Study 1, the participants were significantly less likely to select the box indicated by the arrow during the post-training trials than during the pre-training trials (W = 82, p = .009, Wilcoxon signed-rank test for matched pairs). Thus, receiving feedback about the real location of the reward increased the participants’ tendency to avoid the box indicated by the arrow. In the post-training trials of Study 2, the participants’ tendency to select the box indicated by the arrow did not differ from chance. Thus, we performed complementary analyses of individual strategies to assess whether children simply stopped paying attention to the arrow, or whether they used it in a systematic fashion. These analyses indicated that in Study 2, 22 out of 28 participants kept using the same strategy during the two post-training trials of the test condition (p = .004, two-choice binomial test)—either selecting the box indicated by the arrow twice (n = 11) or avoiding the box that was indicated by the arrow twice (n = 11). These results rule out the possibility that participants simply learned to ignore the arrow. They indicate that the children used the arrow in a systematic fashion during the post-training trials.
Nice Informant Trials (Trials 5 and 6). In Study 2, the average percentage of the nice informant trials in which the participants selected the box indicated by the arrow tended to be higher than predicted by chance (M = 66.07%, SD = 45.25, W = 252, p = .086, one-sample Wilcoxon signed-rank test). The participants did not select the box indicated by the arrow significantly more often during the nice informant trials than during the post-training trials (W = 51.50, p = .1, Wilcoxon signed-rank test for matched pairs).
Baseline trust condition
In the baseline trust condition, participants selected the box indicated by the arrow more often than predicted by chance (M = 93.75%, SD = 17.08, W = 105, p < .001, one-sample Wilcoxon signed-rank test). The participants’ tendency to select the box indicated by the arrow was not significantly higher in the baseline trust condition than in the pre-training trials of the test condition (U = 266, p = .312, Mann-Whitney U test). In contrast, in Study 2, the participants’ tendency to select the box indicated by the arrow tended to be higher in the baseline trust condition than during the post-training trials of the test condition (U = 342, p = .003, Mann-Whitney U test), and during the nice informant trials of the test condition (U = 292, p = .099, Mann-Whitney U test). These results confirm that the children learned to avoid the box indicated by the arrow during the mean informant trials.
In order to focus on the role of learning on performance, we re-analyzed separately the performance of the “learners”, i.e., the participants enrolled in the test condition who selected the box indicated by the mean informant less often during the post-training trials than during the pre-training trials (n = 11). In Study 2, the average percentage of the pre-training trials in which the learners selected the box indicated by the arrow was significantly higher than predicted by chance (M = 95.45%, SD = 14.37, W = 55, p = .001, one-sample Wilcoxon signed-rank test). In contrast, the average percentage of the post-training trials in which Study 2’s learners selected the box indicated by the arrow was significantly lower than predicted by chance (M = 22.73%, SD = 26.11, W = 0, p = .014, one-sample Wilcoxon signed-rank test). Furthermore, the average percentage of the nice informant trials in which Study 2’s learners selected the box indicated by the arrow was significantly lower than predicted by chance (M = 18.18%, SD = 32.14, W = 5, p = .02, one-sample Wilcoxon signed-rank test). Thus, the learners continued to avoid the box indicated by the arrow even when it was manipulated by a benevolent informant. In addition, Study 2’s learners did not select the box indicated by the arrow significantly more often during the nice informant trials than during post-training trials (W = 4, p = .77, Wilcoxon signed-rank test for matched pairs). Moreover, Study 2’s learners’ tendency to select the box indicated by the arrow was significantly higher in the baseline trust condition than during the nice informant trials of the test condition (U = 165, p < .001, Mann-Whitney U test). In short, as in Study 1, the analyses performed on the subgroup of “learners” confirmed the analyses performed on the whole group of participants in Study 2.
The data of Study 2 confirm the pattern of results observed in Study 1. In Study 2, unlike in Study 1, the communicative nature of the unfamiliar signal was made explicit to the participants. Accordingly, they used the unfamiliar signal (the arrow) to locate the toy prior to receiving any feedback about the reward’s location, both when it was used by a benevolent informant (in the baseline trust condition) or by a malevolent informant (in the pre-training trials). Crucially, as in Study 1, Study 2’s participants did not adjust their use of the unfamiliar communicative device to the benevolence of the informant. In Study 2’s test condition, the children who learned to avoid the arrow during the mean informant trials did not change their strategy when presented with a benevolent informant, and they kept avoiding the location indicated by the arrow.
General discussion
Prior to four to five years of age, children keep trusting a misleading informant using a familiar communicative device such as pointing or verbal testimony over many repeated trials [11, 13–16, 27]. In contrast, when the communicative device is less familiar, three - to four-year-olds learn to avoid the location that it indicates. In previous studies, this phenomenon has been interpreted as evidence that what is conveyed by unfamiliar devices is accepted less rigidly than what is communicated by familiar devices such as pointing or verbal testimony [14, 27]. Our studies show that this is not the only interpretation possible.
According to the alternative interpretation suggested by our studies, it is neither that 3-year-olds trust other people in all respects—they understand that mean people do bad things—nor that what they trust are specific and familiar communicative devices. Rather, children view overt, ostensive communication in general as an intrinsically cooperative, ignore the possibility of deception, and hence trust people qua communicators, whether or not these people are nice or mean otherwise. On the basis of this trust in communication, children may reinterpret an unfamiliar communicative device repeatedly indicating a box that turned out to be empty as in fact denoting the empty box.
More specifically, in our Studies, once they started receiving feedback about the location of the pompom, children reduced their tendency to select the box indicated by the unfamiliar communicative device. This, so far, is little more than a conceptual replication of [14, 27] and is merely consistent with our alternative hypothesis. What support this alternative hypothesis is the fact that participants didn’t revise this strategy when the “mean” informant was replaced by a “nice” one as they should have if they trusted this second informant and interpreted the unfamiliar signal as indicating the location of the pompom. Furthermore, in Studies 1 and 2, children’s likelihood of avoiding the location indicated by the unfamiliar communicative device used by a “nice” informant tended to be significantly stronger in the test condition than in the baseline trust condition. This last result was most evident in the sub-group of “learners”, i.e., in the subset of participants who selected the box indicated by the novel signal less often after receiving feedback about the location of the reward (during the post-test trials), than at the beginning of the experiment (during the pre-test trials).
These results are inconsistent with the hypothesis that repeated trials in the initial training phase had helped children to recognize that the uncooperative “mean” informant intended to deceive them. If this hypothesis had been correct, children should have come back to their initial level of baseline trust when presented with a “nice” and cooperative informant. These results are also inconsistent with the hypothesis that what children distrusted was not so much the mean communicator as the unfamiliar communicative device and that they simply learned to ignore this device. If children had treated the unfamiliar communicative devices as uninformative and irrelevant, they should have selected one of the boxes randomly. Rather, they relied systematically on the marker to locate the empty box in Study 1. In the post-training trials of Study 2, the participants used one of two strategies: some children systematically avoided the box that the arrow was pointing to, while other children systematically selected it.
In other words, these results suggest that training had caused children to use the unfamiliar communicative device as a signal reliably indicating the location of the empty box. This “smart trusting hypothesis” postulates that when signals have no predetermined interpretation, young preschoolers can without difficulties interpret them so as to fit their expectation that communication is honest and helpful. Such smart trusting may well play an essential role in helping children infer the meaning of novel words and of other unfamiliar signals. By contrast, reinterpreting a signal whose meaning has been well-established (such as pointing) should be much harder.
The smart trusting hypothesis is compatible with the view that trust in communication comes with the recognition of a behavior as intended to communicate, whatever the nature of the behavior employed. Still, familiarity with communicative means may be important in two other ways. First, the use of familiar signals makes it quite clear that communication is intended whereas unfamiliar forms of communication may not be as easily recognized as communicative. Familiarity with the means employed by the communicator may therefore indirectly increase trust by making it clear that communication is intended in the first place. Indeed, there is evidence showing that children rely more on an unfamiliar signal when it is accompanied by cues indicating an intention to communicate [13, 31]. Such cues do not turn unfamiliar signals into familiar ones. What they do is it makes it clearer that the unfamiliar behavior is used to communicate. Second, even when the intention to communicate has been established, familiar signals may still be harder to re-interpret, quite simply because their meaning has been well-established in the past.
One methodological caveat (identified by a reviewer) from our study is that in the test condition children might learn to inflexibly avoid the box indicated by the novel communicative device. This “inflexible learning” interpretation postulates that children first learned to select the box that was not indicated by the unfamiliar signal, and then did not manage to adjust flexibly their strategy to the change of informants. It should be noted that during the mean informant trials, a large subset of participants learned to systematically avoid the box indicated by the marker (Study 1), or by the arrow (Study 2). Thus, as a group, children did demonstrate the capacity to change their strategy in our Studies. Yet, we cannot entirely rule out that if children participated in more trials with the nice informants they would at some point shift strategy. Crucially, the inflexible learning hypothesis implies that children’s avoidance of the location indicated by an unfamiliar signal is not a demonstration of vigilance towards the potential falsity of what the unfamiliar signal conveys. Thus, regardless of whether our smart trusting hypothesis or the alternative inflexible learning interpretation is true, our study shows that the finding in earlier studies [14, 27] that children can learn to avoid the location indicated by an unfamiliar communicative signal cannot be taken as unambiguous evidence for distrust of such signals.
Our data do not tell why children do not learn to reinterpret familiar signals that are repeatedly misleading [11, 13–14, 27], but this is not much of a puzzle. Young children may simply not revise their interpretation of familiar signals because past experience makes them quite confident about the meaning of these signals (just like adults would not automatically assume that familiar words are used with a different meaning when, taken literally, they convey a misleading message).
Children tested in our study were made to pay attention to the benevolence or malevolence of the informants. Yet, they did not use this information to adjust their acceptance of communicated information. These results are all the more remarkable given that children as young as three properly understand the terms “nice” and “mean” when selecting informants: they prefer to endorse and request testimony from characters that have been said to be “nice” rather than “mean” [12, 32–33]. More generally, by the age of four—the mean age of our participants—children are sensitive to the accuracy with which the terms “nice” and “mean” are employed [34], and they use these terms to make consistent behavioral predictions in a variety of situations [35]. Furthermore, we ensured that children paid attention to what was said to them about the cooperativeness of informants by asking control questions about the benevolence of the informants at the beginning of each trial (“Is it mean?” and “Does it want you to find the pompom?”). Participants who failed to answer correctly these control questions more than three times during the experiment were excluded from the analysis.
Yet, children did not calibrate their reliance on the unfamiliar signal depending on the benevolence of informants. This pattern of results is compatible with the view that before four to five years of age, children have difficulties either with (i) recognizing that malevolent individuals might use deception and lies to achieve their aims, or with (ii) acting upon the knowledge that malevolent informants might use deception (e.g., for executive reasons). Children's inability to flexibly integrate information about the benevolence or malevolence of informants could explain their difficulty with remaining vigilant towards deception from malevolent or uncooperative agents.
Supporting information
S1 Data [xls]
Full dataset.
Zdroje
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- Development and multi-cohort validation of a clinical score for predicting type 2 diabetes mellitus
- Chronic stability of single-channel neurophysiological correlates of gross and fine reaching movements in the rat
- Neural, functional, and aesthetic impacts of spatially heterogeneous flicker: A potential role of natural flicker
- Clinical and laboratorial profiles of dengue virus infection in kidney transplant recipients: Report of a single center
- Bioaccumulation of heavy metals in some commercially important fishes from a tropical river estuary suggests higher potential health risk in children than adults
- Factors associated with unsuppressed viremia in women living with HIV on lifelong ART in the multi-country US-PEPFAR PROMOTE study: A cross-sectional analysis
- Comparing low-cost handheld autorefractors: A practical approach to measuring refraction in low-resource settings
- Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth
- Computational screening of antimicrobial peptides for Acinetobacter baumannii
- Isolation of secreted proteins from Drosophila ovaries and embryos through in vivo BirA-mediated biotinylation
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- Exploring the basis of 2-propenyl and 3-butenyl glucosinolate synthesis by QTL mapping and RNA-sequencing in Brassica juncea
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- Multilevel legal approaches to obesity prevention: A conceptual and methodological toolkit
- Prevalence, associated factors and health impact of intimate partner violence against women in different life stages
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- The effectiveness of a community-based, type 2 diabetes prevention programme on health-related quality of life. The DE-PLAN study
- Predictors, causes, and trends of neonatal mortality at Nekemte Referral Hospital, east Wollega Zone, western Ethiopia (2010–2014). Retrospective cohort study
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- Novel approaches to model effects of subconjunctival blebs on flow pressure to improve clinical grading systems after glaucoma drainage surgery
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- Variation in bone response to the placement of percutaneous osseointegrated endoprostheses: A 24-month follow-up in sheep
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- Anemia and its associated factors among adult people living with human immunodeficiency virus at Wolaita Sodo University teaching referral hospital
- A system for bedside assistance that integrates a robotic bed and a mobile manipulator
- A global sampler of single particle tracking solutions for single molecule microscopy
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- Decrements of body mass index are associated with poor outcomes of idiopathic pulmonary fibrosis patients
- The effectiveness of the quality improvement collaborative strategy in low- and middle-income countries: A systematic review and meta-analysis
- An intrusion detection algorithm for sensor network based on normalized cut spectral clustering
- Pregnane X receptor activation constrains mucosal NF-κB activity in active inflammatory bowel disease
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- Multi-breed genome-wide association studies across countries for electronically recorded behavior traits in local dual-purpose cows
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- Correction: Feed Conversion, Survival and Development, and Composition of Four Insect Species on Diets Composed of Food By-Products
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- A fuzzy logic decision support model for climate-driven biomass loss risk in western Oregon and Washington
- Skeletal development in the sea urchin relies upon protein families that contain intrinsic disorder, aggregation-prone, and conserved globular interactive domains
- Investigating the potential of the secretome of mesenchymal stem cells derived from sickle cell disease patients
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- Impact of group antenatal care (G-ANC) versus individual antenatal care (ANC) on quality of care, ANC attendance and facility-based delivery: A pragmatic cluster-randomized controlled trial in Kenya and Nigeria
- The relationship between management practices and the efficiency and quality of voluntary medical male circumcision services in four African countries
- Using AST-platelet ratio index and fibrosis 4 index for detecting chronic hepatitis C in a large-scale community screening
- Incidence and predictors of retreatment in chronic hepatitis B patients after discontinuation of entecavir or tenofovir treatment
- Elderly HIV-positive women: A gender-based analysis from the Multicenter Italian “GEPPO” Cohort
- Attitudes and perceptions towards hypoglycaemia in patients with diabetes mellitus: A multinational cross-sectional study
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- Association between mitochondrial genetic variation and breast cancer risk: The Multiethnic Cohort
- Incorporating evaporative water loss into bioenergetic models of hibernation to test for relative influence of host and pathogen traits on white-nose syndrome
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- Fisheries governance in the face of climate change: Assessment of policy reform implications for Mexican fisheries
- Modeling sediment oxygen demand in a highly productive lake under various trophic scenarios
- Spread of domestic animals across Neolithic western Anatolia: New stable isotope evidence from Uğurlu Höyük, the island of Gökçeada, Turkey
- Relationship of the lobular branch of the great auricular nerve to the tympanoparotid fascia: Spatial anatomy for salvage during face and neck lift
- Assessing precision and requirements of three methods to estimate roe deer density
- Systematic review and REMARK scoring of renal cell carcinoma prognostic circulating biomarker manuscripts
- Assessing the potential of plains zebra to maintain African horse sickness in the Western Cape Province, South Africa
- Biomechanical effects of rocker shoes on plantar aponeurosis strain in patients with plantar fasciitis and healthy controls
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- Gut microbiome diversity is associated with sleep physiology in humans
- Geospatial analysis of the influence of family doctor on colorectal cancer screening adherence
- Can machine learning improve patient selection for cardiac resynchronization therapy?
- The rotating magnetocaloric effect as a potential mechanism for natural magnetic senses
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- Assessment of community knowledge, practice, and determinants of malaria case households in the rural area of Raya Azebo district, Northern Ethiopia, 2017
- Leadership in informal stormwater governance networks
- Early diagnosis of Alzheimer’s disease using combined features from voxel-based morphometry and cortical, subcortical, and hippocampus regions of MRI T1 brain images
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- The dialogue between protozoa and bacteria in a microfluidic device
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- A new carcharodontosaurian theropod (Dinosauria: Saurischia) from the Lower Cretaceous of Thailand
- Using remote sensing to detect whale strandings in remote areas: The case of sei whales mass mortality in Chilean Patagonia
- Americans preferred Syrian refugees who are female, English-speaking, and Christian on the eve of Donald Trump’s election
- Class III β-tubulin expression as a predictor of docetaxel-resistance in metastatic castration-resistant prostate cancer
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- HaTSPiL: A modular pipeline for high-throughput sequencing data analysis
- The feasibility of using citizens to segment anatomy from medical images: Accuracy and motivation
- Bacterial diversity in Icelandic cold spring sources and in relation to the groundwater amphipod Crangonyx islandicus
- Pathogen surveillance in the informal settlement, Kibera, Kenya, using a metagenomics approach
- Movement and habitat selection of the western spadefoot (Spea hammondii) in southern California
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- The burden of oral conditions among adolescents living with HIV at a clinic in Johannesburg, South Africa
- The impact of peer pressure on cigarette smoking among high school and university students in Ethiopia: A systemic review and meta-analysis
- Substitution of marijuana for opioids in a national survey of US adults
- Strategies for the hypothermic preservation of cell sheets of human adipose stem cells
- Active hepatocellular carcinoma is an independent risk factor of direct-acting antiviral treatment failure: A retrospective study with prospectively collected data
- Microliths in the South Asian rainforest ~45-4 ka: New insights from Fa-Hien Lena Cave, Sri Lanka
- Transgenic cotton and farmers’ health in Pakistan
- Social media as a data resource for #monkseal conservation
- A novel short-term high-lactose culture approach combined with a matrix-assisted laser desorption ionization-time of flight mass spectrometry assay for differentiating Escherichia coli and Shigella species using artificial neural networks
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- Automated clear cell renal carcinoma grade classification with prognostic significance
- Comparative genomic analyses reveal diverse virulence factors and antimicrobial resistance mechanisms in clinical Elizabethkingia meningoseptica strains
- Reading-out task variables as a low-dimensional reconstruction of neural spike trains in single trials
- ‘Fat’s chances’: Loci for phenotypic dispersion in plasma leptin in mouse models of diabetes mellitus
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- Evaluation of soybean genotypes for reaction to natural field infection by Cercospora species causing purple seed stain
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- Model based estimation of population total in presence of non-ignorable non-response
- ESLI: Enhancing slope one recommendation through local information embedding
- Self-adaptive dual-strategy differential evolution algorithm
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- Adverse prognosis of glioblastoma contacting the subventricular zone: Biological correlates
- Widespread chytrid infection across frogs in the Peruvian Amazon suggests critical role for low elevation in pathogen spread and persistence
- Dysfunction of the blood-brain barrier in postoperative delirium patients, referring to the axonal damage biomarker phosphorylated neurofilament heavy subunit
- A low latency and low power indirect topology for on-chip communication
- Development and application of a framework to estimate health care costs in China: The cervical cancer example
- New oral anti-coagulants versus vitamin K antagonists in high thromboembolic risk patients
- Enriched taxa were found among the gut microbiota of centenarians in East China
- Model-based QTL detection is sensitive to slight modifications in model formulation
- Modeling the residential distribution of enrolled students to assess boundary-induced disparities in public school access
- A brief diet intervention can reduce symptoms of depression in young adults – A randomised controlled trial
- Associations of MGMT promoter hypermethylation with squamous intraepithelial lesion and cervical carcinoma: A meta-analysis
- Differences in energy and nutritional content of menu items served by popular UK chain restaurants with versus without voluntary menu labelling: A cross-sectional study
- The association between disordered eating and health-related quality of life among children and adolescents: A systematic review of population-based studies
- Prescribing patterns of polypharmacy in Korean pediatric patients
- Factors associated with directly observed treatment in tuberculosis/HIV coinfection cases in Porto Alegre, 2009-2013: A retrospective cohort
- Evaluation of date palm pollen (Phoenix dactylifera L.) encapsulation, impact on the nutritional and functional properties of fortified yoghurt
- Association between maternal fermented food consumption and infant sleep duration: The Japan Environment and Children's Study
- Discerning the functional networks behind processing of music and speech through human vocalizations
- Preference-based serial decisions are counterintuitively influenced by emotion regulation and conscientiousness
- Subgenotyping and genetic variability of hepatitis C virus in Palestine
- Supra-threshold perception and neural representation of tones presented in noise in conditions of masking release
- Measuring sustainability of seed-funded earth science informatics projects
- Contrast-enhanced spectral mammography with a compact synchrotron source
- Assessing the role of toll-like receptor in isolated, standard and enriched housing conditions
- Inequality in income change among cancer survivors five years after diagnosis: Evidence from a French national survey
- A novel fast-slow model of diabetes progression: Insights into mechanisms of response to the interventions in the Diabetes Prevention Program
- Integrated HIV surveillance finds recent adult hepatitis B virus (HBV) transmission and intermediate HBV prevalence among military in uncharacterized Caribbean country
- Declared impact of the US President’s statements and campaign statements on Latino populations’ perceptions of safety and emergency care access
- Two novel and correlated CF-causing insertions in the (TG)mTn tract of the CFTR gene
- Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis
- Practice and factors associated with active management of third stage of labor among obstetric care providers in Amhara region referral hospitals, North Ethiopia, 2018: A cross sectional study
- Animal-assisted therapy for patients in a minimally conscious state: A randomized two treatment multi-period crossover trial
- Macular thickness measurements of healthy, naïve cynomolgus monkeys assessed with spectral-domain optical coherence tomography (SD-OCT)
- Rice bran oil ameliorates inflammatory responses by enhancing mitochondrial respiration in murine macrophages
- Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs
- The effect of ‘Traffic-Light’ nutritional labelling in carbonated soft drink purchases in Ecuador
- Forma mentis networks quantify crucial differences in STEM perception between students and experts
- A population-based cohort study examining the association of documented bladder diverticulum and bladder cancer risk in urology patients
- Framework for rational donor selection in fecal microbiota transplant clinical trials
- HLA high-resolution typing by next-generation sequencing in Pandemrix-induced narcolepsy
- Health assessment of Conolophus subcristatus, Conolophus pallidus, and C. subcristatus X Amblyrhynchus cristatus hybrid (Galápagos land iguanas)
- Prognostic value of post-induction chemotherapy 18F-FDG PET-CT in stage II/III non-small cell lung cancer before (chemo-) radiation
- Risk factor-based subphenotyping of heart failure in the community
- An efficient and adaptive data-hiding scheme based on secure random matrix
- Endovascular treatment of different types of iliac occlusions—Results from an observational study
- Variation in pickleweed root-associated microbial communities at different locations of a saline solid waste management unit contaminated with petroleum hydrocarbons
- Consumption of rice, acceptability and sensory qualities of fortified rice amongst consumers of social safety net rice in Nepal
- Quantitative analysis of the bilateral coordination and gait asymmetry using inertial measurement unit-based gait analysis
- Application of metagenomic shotgun sequencing to detect vector-borne pathogens in clinical blood samples
- Higher underestimation of tumour size post-neoadjuvant chemotherapy with breast magnetic resonance imaging (MRI)—A concordance comparison cohort analysis
- Wealth accumulation in rotation forestry – Failure of the net present value optimization?
- Increased incidence of age-related macular degeneration in sensorineural hearing loss: A population-based cohort study
- Evaluating the foundations that help avert antimicrobial resistance: Performance of essential water sanitation and hygiene functions in hospitals and requirements for action in Kenya
- Effects of a hot ambient operating theatre on manual dexterity, psychological and physiological parameters in staff during a simulated burn surgery
- Introduction of quality management in a National Reference Laboratory in Germany
- Histopathological investigation of complex gill disease in sea farmed Atlantic salmon
- Common variants in glyoxalase I do not increase chronic pancreatitis risk
- Cognitive impairment in multiple sclerosis: An exploratory analysis of environmental and lifestyle risk factors
- Japanese nationwide survey of hypophosphatasia reveals prominent differences in genetic and dental findings between odonto and non-odonto types
- Interaction of detergents with biological membranes: Comparison of fluorescence assays with filtration protocols and implications for the rates of detergent association, dissociation and flip-flop
- Potential causes of early death among admitted newborns in a rural Tanzanian hospital
- Identification of glomerular and podocyte-specific genes and pathways activated by sera of patients with focal segmental glomerulosclerosis
- Prevalence and correlates of partner violence among adolescent girls and young women: Evidence from baseline data of a cluster randomised trial in Tanzania
- Development of an integrated fingerstick blood self-collection device for radiation countermeasures
- Concordance between gene expression in peripheral whole blood and colonic tissue in children with inflammatory bowel disease
- Effects of arthroscopic vs. mini-open rotator cuff repair on function, pain & range of motion. A systematic review and meta-analysis
- Broiler welfare trade-off: A semi-quantitative welfare assessment for optimised welfare improvement based on an expert survey
- Engagement in care among women and their infants lost to follow-up under Option B+ in eSwatini
- Hyperglycemia in the early stages of type 1 diabetes accelerates gastric emptying through increased networks of interstitial cells of Cajal
- Nanoaperture fabrication via colloidal lithography for single molecule fluorescence analysis
- A rapid, low pH, nutrient stress, assay to determine the bactericidal activity of compounds against non-replicating Mycobacterium tuberculosis
- Sialochemical analysis in polytraumatized patients in intensive care units
- The black sheep effect: The case of the deviant ingroup robot
- No relationship between fornix and cingulum degradation and within-network decreases in functional connectivity in prodromal Alzheimer’s disease
- Implementation of an international standardized set of outcome indicators in pregnancy and childbirth in Kenya: Utilizing mobile technology to collect patient-reported outcomes
- Breastfeeding support through wet nursing during nutritional emergency: A cross sectional study from Rohingya refugee camps in Bangladesh
- Does route matter? Impact of route of oxytocin administration on postpartum bleeding: A double-blind, randomized controlled trial
- Research on OpenCL optimization for FPGA deep learning application
- Drug therapy problems, medication adherence and treatment satisfaction among diabetic patients on follow-up care at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
- Quality of life and symptom intensity over time in people with cancer receiving palliative care: Results from the international European Palliative Care Cancer Symptom study
- The dynamics of Early Celtic consumption practices: A case study of the pottery from the Heuneburg
- Safety and efficacy of artesunate-amodiaquine combined with either methylene blue or primaquine in children with falciparum malaria in Burkina Faso: A randomized controlled trial
- “Cementing” marriages through childbearing in subsequent unions: Insights into fertility differentials among first-time married and remarried women in Ghana
- Single session high definition transcranial direct current stimulation to the cerebellum does not impact higher cognitive function
- The contribution of age structure to the international homicide decline
- Genetic structure of Mexican lionfish populations in the southwest Gulf of Mexico and the Caribbean Sea
- A physiological dose of oral vitamin B-12 improves hematological, biochemical-metabolic indices and peripheral nerve function in B-12 deficient Indian adolescent women
- Nutritional status, cognitive achievement, and educational attainment of children aged 8-11 in rural South India
- Costs and cost-effectiveness analyses of mCARE strategies for promoting care seeking of maternal and newborn health services in rural Bangladesh
- Cause-specific mortality in the general population with transient dipstick-proteinuria
- Assessing hand dysfunction in cervical spondylotic myelopathy
- KETOS: Clinical decision support and machine learning as a service – A training and deployment platform based on Docker, OMOP-CDM, and FHIR Web Services
- Variation in activity rates may explain sex-specific dorsal color patterns in Habronattus jumping spiders
- Adjusting for spatial variation when assessing individual-level risk: A case-study in the epidemiology of snake-bite in Sri Lanka
- Acute sprint exercise transcriptome in human skeletal muscle
- Parenting and personality disorder: An overview and meta-synthesis of systematic reviews
- Female rats release a trapped cagemate following shaping of the door opening response: Opening latency when the restrainer was baited with food, was empty, or contained a cagemate
- Multiplex communities and the emergence of international conflict
- The impact of socioeconomic status on emergency department outcome in a low-income country setting: A registry-based analysis
- Effect of psycho-social support by teachers on improving mental health and hope of adolescents in an earthquake-affected district in Nepal: A cluster randomized controlled trial
- A cluster-randomized controlled trial of the effectiveness of the JUMP Math program of math instruction for improving elementary math achievement
- Transgenic mouse model for conditional expression of influenza hemagglutinin-tagged human SLC20A1/PIT1
- Use of rapid Model for End-Stage Liver Disease (MELD) increases for liver transplant registrant prioritization after MELD-Na and Share 35, an evaluation using data from the United Network for Organ Sharing
- Fishery Improvement Projects as a governance tool for fisheries sustainability: A global comparative analysis
- QRStree: A prefix tree-based model to fetal QRS complexes detection
- Fundraising and vote distribution: A non-equilibrium statistical approach
- Evaluation of PRRSv specific, maternally derived and induced immune response in Ingelvac PRRSFLEX EU vaccinated piglets in the presence of maternally transferred immunity
- Gene expression profiling of whole blood: A comparative assessment of RNA-stabilizing collection methods
- Alteration of adipose tissue immune cell milieu towards the suppression of inflammation in high fat diet fed mice by flaxseed oil supplementation
- Isoniazid preventive therapy: Uptake, incidence of tuberculosis and survival among people living with HIV in Bulawayo, Zimbabwe
- P16 methylation increases the sensitivity of cancer cells to the CDK4/6 inhibitor palbociclib
- Using long-term datasets to assess the impacts of dietary exposure to neonicotinoids on farmland bird populations in England
- Genetic mapping of distal femoral, stifle, and tibial radiographic morphology in dogs with cranial cruciate ligament disease
- Optimized bioluminescence analysis of adenosine triphosphate (ATP) released by platelets and its application in the high throughput screening of platelet inhibitors
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- An observational study on intracutaneous sodium storage in intensive care patients and controls
- Recovery when you are on your own: Slow population responses in an isolated marine reserve
- How does the method change what we measure? Comparing virtual reality and text-based surveys for the assessment of moral decisions in traffic dilemmas
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- Analytical validation of the Target Selector ctDNA platform featuring single copy detection sensitivity for clinically actionable EGFR, BRAF, and KRAS mutations
- Comparison of two swept-source optical coherence tomography biometers and a partial coherence interferometer
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- A social media intervention to improve nutrition knowledge and behaviors of low income, pregnant adolescents and adult women
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- E-MOVIE - Experimental MOVies for Induction of Emotions in neuroscience: An innovative film database with normative data and sex differences
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- An elevated glycemic gap predicts adverse outcomes in diabetic patients with necrotizing fasciitis
- 40-Hz auditory steady-state responses and the complex information processing: An exploratory study in healthy young males
- Highly diverse anaerobe-predominant vaginal microbiota among HIV-infected pregnant women in Zambia
- Decision-based models of the implementation of interventions in systems of healthcare: Implementation outcomes and intervention effectiveness in complex service environments
- Dual number-based variational data assimilation: Constructing exact tangent linear and adjoint code from nonlinear model evaluations
- Ultra-deep sequencing reveals pre-mRNA splicing as a sequence driven high-fidelity process
- Use of IoT sensing and occupant surveys for determining the resilience of buildings to forest fire generated PM2.5
- Classification of neurons in the adult mouse cochlear nucleus: Linear discriminant analysis
- Lek-associated movement of a putative Ebolavirus reservoir, the hammer-headed fruit bat (Hypsignathus monstrosus), in northern Republic of Congo
- Attenuation correction using 3D deep convolutional neural network for brain 18F-FDG PET/MR: Comparison with Atlas, ZTE and CT based attenuation correction
- Differences in macular capillary parameters between healthy black and white subjects with Optical Coherence Tomography Angiography (OCTA)
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- Chitotetraose activates the fungal-dependent endosymbiotic signaling pathway in actinorhizal plant species
- What is the optimum time for initiation of early mobilization in mechanically ventilated patients? A network meta-analysis
- Cognitive aptitude, peers, and trajectories of marijuana use from adolescence through young adulthood
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- Accuracy and interobserver-agreement of respiratory rate measurements by healthcare professionals, and its effect on the outcomes of clinical prediction/diagnostic rules
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- The Univariate Flagging Algorithm (UFA): An interpretable approach for predictive modeling
- Profiles and trajectories of impaired social cognition in people with Prader-Willi syndrome
- Effect of pimobendan on physical fitness, lactate and echocardiographic parameters in dogs with preclinical mitral valve disease without cardiomegaly
- Sub-types of safety behaviours and their effects on social anxiety disorder
- Engaging in prosocial behavior explains how high self-control relates to more life satisfaction: Evidence from three Chinese samples
- Artificial fingerprints for cross-comparison of forensic DNA and protein recovery methods
- The organization of Golgi in Drosophila bristles requires microtubule motor protein function and a properly organized microtubule array
- Direct and moderating effects of environmental regulation intensity on enterprise technological innovation: The case of China
- Prevalence and associated factors of depression among Korean adolescents
- Transcriptome analysis of PK-15 cells in innate immune response to porcine deltacoronavirus infection
- Geographic variation in cardiometabolic risk distribution: A cross-sectional study of 256,525 adult residents in the Illawarra-Shoalhaven region of the NSW, Australia
- Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury
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- A feature selection strategy for gene expression time series experiments with hidden Markov models
- Dissociating the sequential dependency of subjective temporal order from subjective simultaneity
- Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis
- Population-based estimates of engagement in HIV care and mortality using double-sampling methods following home-based counseling and testing in western Kenya
- Vaginal temperature as indicative of thermoregulatory response in Nellore heifers under different microclimatic conditions
- Galectin-9 gene (LGALS9) polymorphisms are associated with rheumatoid arthritis in Brazilian patients
- The association of brightness with number/duration in human newborns
- Microslit on a chip: A simplified filter to capture circulating tumor cells enlarged with microbeads
- Integrating continuous differential evolution with discrete local search for meander line RFID antenna design
- The impact of the French soda tax on prices and purchases. An ex post evaluation
- Development and validation of monoclonal antibodies against N6-methyladenosine for the detection of RNA modifications
- Structural characterization of a novel polysaccharide from Sargassum thunbergii and its antioxidant and anti-inflammation effects
- Potential biomarker identification for Friedreich’s ataxia using overlapping gene expression patterns in patient cells and mouse dorsal root ganglion
- Major drug resistance mutations to HIV-1 protease inhibitors (PI) among patients exposed to PI class failing antiretroviral therapy in São Paulo State, Brazil
- Chile (Capsicum annuum) plants transformed with the RB gene from Solanum bulbocastanum are resistant to Phytophthora capsici
- Outcomes of acute coronary syndrome patients with concurrent extra-cardiac vascular disease in the era of transradial coronary intervention: A retrospective multicenter cohort study
- Analysis of gene co-expression networks of phosphate starvation and aluminium toxicity responses in Populus spp.
- Risk factors associated with IgA vasculitis with nephritis (Henoch–Schönlein purpura nephritis) progressing to unfavorable outcomes: A meta-analysis
- The prediction model of suicidal thoughts in Korean adults using Decision Tree Analysis: A nationwide cross-sectional study
- A multidimensional understanding of prosperity and well-being at country level: Data-driven explorations
- Factors associated with muscle mass in community-dwelling older people in Singapore: Findings from the SHIELD study
- The prevalence and risk of non-infectious comorbidities in HIV-infected and non-HIV infected men attending general practice in Australia
- Vibrio cholerae strains with inactivated cqsS gene overproduce autoinducer-2 which enhances resuscitation of dormant environmental V. cholerae
- Myocardial function in patients with anomalous left coronary artery from the pulmonary artery syndrome: A long-term speckle tracking echocardiographic study
- Enhanced anti-tumor effect of liposomal Fasudil on hepatocellular carcinoma in vitro and in vivo
- Joint distribution for number of crossings and longest run in independent Bernoulli observations. The R package crossrun
- Learning to play badminton altered resting-state activity and functional connectivity of the cerebellar sub-regions in adults
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- Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease
- Precluding rare outcomes by predicting their absence
- Tidal inlet seafloor changes induced by recently built hard structures
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- Effect of host genotype and Eimeria acervulina infection on the metabolome of meat-type chickens
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- The impact of PEPFAR transition on HIV service delivery at health facilities in Uganda
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- Correction: Activation of aryl hydrocarbon receptor signaling by a novel agonist ameliorates autoimmune encephalomyelitis
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- Behavioral recovery and spinal motoneuron remodeling after polyethylene glycol fusion repair of singly cut and ablated sciatic nerves
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- The intriguing effect of ethanol and nicotine on acetylcholine-sensitive potassium current IKAch: Insight from a quantitative model
- The accumulation of deficits approach to describe frailty
- Botulinum toxin A injection into the entopeduncular nucleus improves dynamic locomotory parameters in hemiparkinsonian rats
- Turing complete neural computation based on synaptic plasticity
- Influence of mydriasis on optical coherence tomography angiography imaging in patients with age-related macular degeneration
- Specialized care improves outcomes for patients with cirrhosis who require general surgical operations
- Association between plural legal systems and sexual and reproductive health outcomes for women and girls in Nigeria: A state-level ecological study
- 3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
- Utility of qSOFA and modified SOFA in severe malaria presenting as sepsis
- Correction: Perspectives of general dental practitioners on preventive, patient-centred, and evidence-based oral healthcare—A Q-methodology study
- Early detection and differential serodiagnosis of Mycoplasma hyorhinis and Mycoplasma hyosynoviae infections under experimental conditions
- No evidence of associations between ADHD and event-related brain potentials from a continuous performance task in a population-based sample of adolescent twins
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- Simultaneous cardiac and respiratory inhibition during seizure precedes death in the DBA/1 audiogenic mouse model of SUDEP
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- Dinosaur ichnology and sedimentology of the Chignik Formation (Upper Cretaceous), Aniakchak National Monument, southwestern Alaska; Further insights on habitat preferences of high-latitude hadrosaurs
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- Effects of dietary intake and nutritional status on cerebral oxygenation in patients with chronic kidney disease not undergoing dialysis: A cross-sectional study
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- An observational study comparing HPV prevalence and type distribution between HPV-vaccinated and -unvaccinated girls after introduction of school-based HPV vaccination in Norway
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- Analysing linear multivariate pattern transformations in neuroimaging data
- Ecological aesthetic assessment of a rebuilt wetland restored from farmland and management implications for National Wetland Parks
- A method for predicting background advertisement exposure parameters in sporting events: Televised football game approach
- Self-reported and experimentally induced self-disgust is heightened in Parkinson’s disease: Contribution of behavioural symptoms
- Associations between nocturnal sleep duration, midday nap duration and body composition among adults in Southwest China
- Short-term effects of video gaming on brain response during working memory performance
- Molecular detection and genetic characterization of Bartonella species from rodents and their associated ectoparasites from northern Tanzania
- Estimation of the number of HCV-positive patients in Italy
- Comparative cost analysis of point-of-care versus laboratory-based testing to initiate and monitor HIV treatment in South Africa
- Insights into the behavior of six rationally designed peptides based on Escherichia coli’s OmpA at the water-dodecane interface
- Identification of muscle-specific candidate genes in Simmental beef cattle using imputed next generation sequencing
- A game theoretic setting of capitation versus fee-for-service payment systems
- In utero exposure to economic fluctuations and birth outcomes: An analysis of the relevance of the local unemployment rate in Brazilian state capitals
- QTL mapping for aluminum tolerance in RIL population of soybean (Glycine max L.) by RAD sequencing
- Establishing an infrastructure for collaboration in primate cognition research
- Evaluation of left ventricular dimension and systolic function by standard transthoracic echocardiography before and 24-hours after percutaneous closure of patent ductus arteriosus in 120 dogs
- Modeling environmental variability and network formation among pastoral nomadic households: Implications for the rise of the Mongol Empire
- Changes in real-life practice for hepatocellular carcinoma patients in the Republic of Korea over a 12-year period: A nationwide random sample study
- Correction: Homology analysis of malware based on ensemble learning and multifeatures
- Illness beliefs and emotional responses in mildly disabled stroke survivors: A qualitative study
- Extended-wavelength diffuse reflectance spectroscopy with a machine-learning method for in vivo tissue classification
- Modeling the natural history of fatty liver using lifestyle–related risk factors: Effects of body mass index (BMI) on the life–course of fatty liver
- Development of a recombinant replication-deficient rabies virus-based bivalent-vaccine against MERS-CoV and rabies virus and its humoral immunogenicity in mice
- Educational achievement at age 9.5 years of children born to mothers maintained on methadone during pregnancy
- Comparative transcriptome analysis of galls from four different host plants suggests the molecular mechanism of gall development
- Experiences with peer support for breastfeeding in Beirut, Lebanon: A qualitative study
- Elucidating optical field directed hierarchical self-assembly of homogenous versus heterogeneous nanoclusters with femtosecond optical tweezers
- Structure establishment of three-dimensional (3D) cell culture printing model for bladder cancer
- Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality
- Correction: Functional atlases for analysis of motor and neuropsychological outcomes after medial globus pallidus and subthalamic stimulation
- Correction: Estimating Body Composition in Adolescent Sprint Athletes: Comparison of Different Methods in a 3 Years Longitudinal Design
- Quality of labor and birth care in Sindh Province, Pakistan: Findings from direct observations at health facilities
- A comparison of sLASER and MEGA-sLASER using simultaneous interleaved acquisition for measuring GABA in the human brain at 7T
- Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis
- Intrabladder pressure as predictor of intra-abdominal pressure in horses
- Pollock avoided hydrodynamic instabilities to paint with his dripping technique
- Metabolomic analysis of the occurrence of bitter fruits on grafted oriental melon plants
- Photo-degradation dynamics of five neonicotinoids: Bamboo vinegar as a synergistic agent for improved functional duration
- Use of acoustic emission to identify novel candidate biomarkers for knee osteoarthritis (OA)
- Cetacean biodiversity, spatial and temporal trends based on stranding records (1920-2016), Victoria, Australia
- Neutrophil elastase inhibitor purification strategy from cowpea seeds
- Correction: Hafting of Middle Paleolithic tools in Latium (central Italy): New data from Fossellone and Sant’Agostino caves
- Coherent poly propagation materials with 3-dimensional photonic control over visible light
- Characterization of Worldwide Olive Germplasm Banks of Marrakech (Morocco) and Córdoba (Spain): Towards management and use of olive germplasm in breeding programs
- Can non-pharmacological interventions reduce hospital admissions in people with dementia? A systematic review
- Metarhizium robertsii ammonium permeases (MepC and Mep2) contribute to rhizoplane colonization and modulates the transfer of insect derived nitrogen to plants
- Genotyping and antimicrobial resistance of Streptococcus uberis isolated from bovine clinical mastitis
- Isotopic compositions of ground ice in near-surface permafrost in relation to vegetation and microtopography at the Taiga–Tundra boundary in the Indigirka River lowlands, northeastern Siberia
- Financial inclusion and intimate partner violence: What does the evidence suggest?
- Are intestinal helminths playing a positive role in tuberculosis risk? A systematic review and meta-analysis
- Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition
- Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer
- Take one step backward to move forward: Assessment of genetic diversity and population structure of captive Asian woolly-necked storks (Ciconia episcopus)
- Money doesn’t matter! Householders’ intentions to reduce standby power are unaffected by personalised pecuniary feedback
- Validating a scale to measure engineers’ perceived self-efficacy for engineering education outreach
- Effect of d-cycloserine on fear extinction training in adults with social anxiety disorder
- Nursing students and nurses’ knowledge and attitudes regarding children’s pain: A comparative cross-sectional study
- Inter-method and anatomical correlates of episodic memory tests in the Alzheimer’s Disease spectrum
- Knowledge, attitudes and medical practice regarding hepatitis B prevention and management among healthcare workers in Northern Vietnam
- Development and validation of a symptom assessment tool for postmicturition dribble: A prospective, multicenter, observational study in Korea
- Identification of closely related Ixodes species by protein profiling with MALDI-TOF mass spectrometry
- When calculators lie: A demonstration of uncritical calculator usage among college students and factors that improve performance
- Socio-economic characteristics and career intentions of the WiSDOM health professional cohort in South Africa
- Correction: Neural computational model GrowthEstimate: A model for studying living resources through digestive efficiency
- Social proximity in dairy calves is affected by differences in pessimism
- Amphibian skin-associated Pigmentiphaga: Genome sequence and occurrence across geography and hosts
- Expanded consumer niche widths may signal an early response to spatial protection
- Moral grandstanding in public discourse: Status-seeking motives as a potential explanatory mechanism in predicting conflict
- Adipose stem cells in reparative goat mastitis mammary gland
- Seventy-five mosses and liverworts found frozen with the late Neolithic Tyrolean Iceman: Origins, taphonomy and the Iceman’s last journey
- Hyaluronic acid and epidermal growth factor improved the bovine embryo quality by regulating the DNA methylation and expression patterns of the focal adhesion pathway
- Associations among knowledge, attitudes, and practices toward palliative care consultation service in healthcare staffs: A cross-sectional study
- A novel, wearable, electronic visual aid to assist those with reduced peripheral vision
- Genetic diversity and population structure of the Mediterranean sesame core collection with use of genome-wide SNPs developed by double digest RAD-Seq
- Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression
- Mobile health-based physical activity intervention for individuals with spinal cord injury in the community: A pilot study
- Factors influencing cultivated ginseng (Panax ginseng C. A. Meyer) bioactive compounds
- Estimation of soil pH with geochemical indices in forest soils
- Multiplexed editing of a begomovirus genome restricts escape mutant formation and disease development
- Correlates of longitudinal leukocyte telomere length in the Costa Rican Longevity Study of Healthy Aging (CRELES): On the importance of DNA collection and storage procedures
- Collaboration and followership: A stochastic model for activities in social networks
- Evaluating access to oral anti-diabetic medicines: A cross-sectional survey of prices, availability and affordability in Shaanxi Province, Western China
- Comparison of corneal elevation and pachymetry measurements made by two state of the art corneal tomographers with different measurement principles
- Use of a pressure-sensing walkway system for biometric assessment of gait characteristics in goats
- Current status and direct medical cost of amyotrophic lateral sclerosis in the region of Catalonia: A population-based analysis
- Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion
- Can work climate foster pro-environmental behavior inside and outside of the workplace?
- Gene editing of PKLR gene in human hematopoietic progenitors through 5’ and 3’ UTR modified TALEN mRNA
- Pelvic alignment changes during the perinatal period
- Interatrial blocks prevalence and risk factors for human immunodeficiency virus-infected persons
- Life-course trajectories of body mass index and subsequent cardiovascular risk among Chinese population
- Inhibitory interaction networks among coevolved Streptomyces populations from prairie soils
- Exploiting contextual information to improve call prediction
- Visual inputs decrease brain activity in frontal areas during silent lipreading
- The synergistic effects of TaAGP.L-B1 and TaSSIVb-D mutations in wheat lead to alterations of gene expression patterns and starch content in grain development
- Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets
- Robust, real-time generic detector based on a multi-feature probabilistic method
- Maize leaves drought-responsive genes revealed by comparative transcriptome of two cultivars during the filling stage
- Xenon lamps used for fruit surface sterilization can increase the content of total flavonols in leaves of Lactuca sativa L. without any negative effect on net photosynthesis
- An alternative procedure to obtain the mortality rate with non-linear functions: Application to the case of the Spanish population
- Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis
- Longitudinal assessment of post-surgical physical activity in endometrial and ovarian cancer patients
- THINGS: A database of 1,854 object concepts and more than 26,000 naturalistic object images
- Evaluation of ranibizumab and aflibercept for the treatment of diabetic macular edema in daily clinical practice
- Proteomic analysis of Escherichia coli detergent-resistant membranes (DRM)
- Correction: Effect of curcuminoids and curcumin derivate products on thioredoxin-glutathione reductase from Taenia crassiceps cysticerci. Evidence suggesting a curcumin oxidation product as a suitable inhibitor
- Correction: Predicting childhood obesity using electronic health records and publicly available data
- Correction: Estimating the value of tropical coastal wetland habitats to fisheries: Caveats and assumptions
- Correction: The effects of sympathetic activity induced by ice water on blood flow and brachial artery flow-mediated dilatation response in healthy volunteers
- Determinants of frailty development and progression using a multidimensional frailty index: Evidence from the English Longitudinal Study of Ageing
- Supporting informed clinical trial decisions: Results from a randomized controlled trial evaluating a digital decision support tool for those with intellectual disability
- BMAL1 associates with chromosome ends to control rhythms in TERRA and telomeric heterochromatin
- Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry
- Hepatopulmonary syndrome has low prevalence of pulmonary vascular abnormalities on chest computed tomography
- Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
- Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15
- The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population
- Expression of Concern: The Coordination of Cell Growth during Fission Yeast Mating Requires Ras1-GTP Hydrolysis
- Correction: Lentivirus-Mediated Knockdown of Astrocyte Elevated Gene-1 Inhibits Growth and Induces Apoptosis through MAPK Pathways in Human Retinoblastoma Cells
- Relationship between self-disclosure to first acquaintances and subjective well-being in people with schizophrenia spectrum disorders living in the community
- Remarkable cell recovery from cerebral ischemia in rats using an adaptive escalator-based rehabilitation mechanism
- Integrating environmental and neighborhood factors in MaxEnt modeling to predict species distributions: A case study of Aedes albopictus in southeastern Pennsylvania
- Post-overdose interventions triggered by calling 911: Centering the perspectives of people who use drugs (PWUDs)
- The prevalence of intimate partner violence among couples signing up for universally offered parent preparation
- Analysis of gear surface morphology based on gray level co-occurrence matrix and fractal dimension
- Abiotic, present-day and historical effects on species, functional and phylogenetic diversity in dry grasslands of different age
- Clonality analysis of pulmonary tumors by genome-wide copy number profiling
- A relictual troglomorphic harvestman discovered in a volcanic cave of western Argentina: Otilioleptes marcelae, new genus, new species, and Otilioleptidae, new family (Arachnida, Opiliones, Gonyleptoidea)
- HIV drug resistance in persons who inject drugs enrolled in an HIV prevention trial in Indonesia, Ukraine, and Vietnam: HPTN 074
- Dietary acid load significantly predicts 10-years survival in patients underwent coronary artery bypass grafting (CABG) surgery
- Regulation of nitrogen availability results in changes in grain protein content and grain storage subproteomes in barley (Hordeum vulgare L.)
- Diagnostic test evaluation methodology: A systematic review of methods employed to evaluate diagnostic tests in the absence of gold standard – An update
- Longitudinal trends of and factors associated with inappropriate antibiotic prescribing for non-bacterial acute respiratory tract infection in Japan: A retrospective claims database study, 2012–2017
- Revealing users’ experience and social interaction outcomes following a web-based smoking prevention intervention for adolescents: A qualitative study
- Coordination of human movements resulting in motor strategies exploited by skilled players during a throwing task
- Impact of pericardiectomy on exercise capacity and sleep of patients with chronic constrictive pericarditis
- Blue-violet light decreases VEGFa production in an in vitro model of AMD
- Identification of protein changes in the blood plasma of lung cancer patients subjected to chemotherapy using a 2D-DIGE approach
- Speed of processing training and depression in assisted and independent living: A randomized controlled trial
- Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient
- What happens in the brain of meditators when perception changes but not the stimulus?
- Comparison of HIV-1 Vif and Vpu accessory proteins for delivery of polyepitope constructs harboring Nef, Gp160 and P24 using various cell penetrating peptides
- Are degree of urbanisation and travel times to healthcare services associated with the processes of care and outcomes of heart failure? A retrospective cohort study based on administrative data
- A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing
- Influence of transcutaneous vagus nerve stimulation on cardiac vagal activity: Not different from sham stimulation and no effect of stimulation intensity
- Co-prescription network reveals social dynamics of opioid doctor shopping
- Contractile properties of superficial skeletal muscle affect postural control in healthy young adults: A test of the rambling and trembling hypothesis
- Does intrauterine crowding affect the force generating capacity and muscle composition of the piglet front limb?
- Correction: Measuring compassionate healthcare with the 12-item Schwartz Center Compassionate Care Scale
- Facilitators and barriers to traditional medicine use among cancer patients in Malawi
- Expression of CMV protein pp65 in cutaneous malignant melanoma
- The evolution of mental health outcomes across a combat deployment cycle: A longitudinal study of a Guam-based National Guard unit
- Caesarean section delivery and childhood obesity in a British longitudinal cohort study
- Incidence, characteristics, and mortality of infective endocarditis in France in 2011
- Pfcyp51 exclusively determines reduced sensitivity to 14α-demethylase inhibitor fungicides in the banana black Sigatoka pathogen Pseudocercospora fijiensis
- Evaluation of the bacterial ocular surface microbiome in clinically normal cats before and after treatment with topical erythromycin
- Histological and developmental insights into the herbivorous dentition of tapinocephalid therapsids
- Differential immunomodulation of T-cells by immunoglobulin replacement therapy in primary and secondary antibody deficiency
- A longitudinal study on perceived health in cardiovascular patients: The role of conscientiousness, subjective wellbeing and cardiac self-efficacy
- The effectiveness of interferon beta versus glatiramer acetate and natalizumab versus fingolimod in a Polish real-world population
- Interactions of Streptococcus suis serotype 9 with host cells and role of the capsular polysaccharide: Comparison with serotypes 2 and 14
- Honey bee and native solitary bee foraging behavior in a crop with dimorphic parental lines
- A flexible formula for incorporating distributive concerns into cost-effectiveness analyses: Priority weights
- Correction: Lack of association between hypothyroxinemia of prematurity and transient thyroid abnormalities with adverse long term neurodevelopmental outcome in very low birth weight infants
- A reconnaissance survey of farmers’ awareness of hypomagnesaemic tetany in UK cattle and sheep farms
- Health workers’ perception of malaria rapid diagnostic test and factors influencing compliance with test results in Ebonyi state, Nigeria
- Conformational flexibility of fork-remodeling helicase Rad5 shown by full-ensemble hybrid methods
- The increasing importance of fellowships and career development awards in the careers of early-stage biomedical academic researchers
- Occurrence and stability of hetero-hexamer associations formed by β-carboxysome CcmK shell components
- Auxin driven indoleamine biosynthesis and the role of tryptophan as an inductive signal in Hypericum perforatum (L.)
- Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development
- Distance to large rivers affects fish diversity patterns in highly dynamic streams of Central Amazonia
- Real vs. immersive-virtual emotional experience: Analysis of psycho-physiological patterns in a free exploration of an art museum
- Modulation of brain tumor risk by genetic SNPs in PARP1gene: Hospital based case control study
- Processed meat intake and chronic disease morbidity and mortality: An overview of systematic reviews and meta-analyses
- Modeling ENSO impact on rice production in the Mekong River Delta
- The feasibility of a behavioral group intervention after weight-loss surgery: A randomized pilot trial
- EMR-integrated minimal core dataset for routine health care and multiple research settings: A case study for neuroinflammatory demyelinating diseases
- A review of a 13-month period of FilmArray Meningitis/Encephalitis panel implementation as a first-line diagnosis tool at a university hospital
- Increased BMI has a linear association with late-onset preeclampsia: A population-based study
- Autoantibody production significantly decreased with APRIL/BLyS blockade in murine chronic rejection kidney transplant model
- Vancomycin-resistance gene cluster, vanC, in the gut microbiome of acute leukemia patients undergoing intensive chemotherapy
- Telomere length in COPD: Relationships with physical activity, exercise capacity, and acute exacerbations
- Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP
- Impact of faecal calprotectin measurement on clinical decision-making in patients with Crohn’s disease and ulcerative colitis
- Additive effects of a small molecular PCNA inhibitor PCNA-I1S and DNA damaging agents on growth inhibition and DNA damage in prostate and lung cancer cells
- Autophagy is important to the acidogenic metabolism of Aspergillus niger
- Continuous ratings of movie watching reveal idiosyncratic dynamics of aesthetic enjoyment
- Sensitivity and specificity of serum soluble interleukin-2 receptor for diagnosing sarcoidosis in a population of patients suspected of sarcoidosis
- Enhancing genomic selection by fitting large-effect SNPs as fixed effects and a genotype-by-environment effect using a maize BC1F3:4 population
- Quantitation and modeling of post-translational modifications in a therapeutic monoclonal antibody from single- and multiple-dose monkey pharmacokinetic studies using mass spectrometry
- Microbial induced solidification and stabilization of municipal solid waste incineration fly ash with high alkalinity and heavy metal toxicity
- Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses
- A fault-tolerant aware scheduling method for fog-cloud environments
- Correction: BCG vaccination and tuberculosis prevention: A forty years cohort study, Monastir, Tunisia
- Correction: Perceptions among transgender women of factors associated with the access to HIV/AIDS-related health services in Yogyakarta, Indonesia
- Assessing the convergent validity between the automated emotion recognition software Noldus FaceReader 7 and Facial Action Coding System Scoring
- Deep learning based banana plant detection and counting using high-resolution red-green-blue (RGB) images collected from unmanned aerial vehicle (UAV)
- Comparison of cardiorespiratory fitness between preschool children with normal and excess body adipose ~ An observational study
- Intraregional differences in renal function in the Northern Netherlands: The Lifelines Cohort Study
- Effects of MCHM on yeast metabolism
- Signaling impacts of GMO labeling on fruit and vegetable demand
- Dietary specialization depending on ecological context and sexual differences in Asiatic black bears
- Electronic device use and beverage related sugar and caffeine intake in US adolescents
- Isolation and characterization of five novel probiotic strains from Korean infant and children faeces
- Correction: Silymarin in non-cirrhotics with non-alcoholic steatohepatitis: A randomized, double-blind, placebo controlled trial
- Correction: Anatomical analysis of antebrachial cutaneous nerve distribution pattern and its clinical implications for sensory reconstruction
- Endothelial nitric oxide synthase limits host immunity to control disseminated Candida albicans infections in mice
- Lack of detection of Candida nivariensis and Candida bracarensis among 440 clinical Candida glabrata sensu lato isolates in Kuwait
- Nonlinear dynamics captures brain states at different levels of consciousness in patients anesthetized with propofol
- Visual encounters on line transect surveys under-detect carnivore species: Implications for assessing distribution and conservation status
- Menstrual health communication among Indian adolescents: A mixed-methods study
- Fast fluorescence in situ hybridisation for the enhanced detection of MET in non-small cell lung cancer
- The influence of personality on the effect of iTBS after being stressed on cortisol secretion
- Parental and peer support and modelling in relation to domain-specific physical activity participation in boys and girls from Germany
- Oral delivery of water-soluble compounds to the phytoseiid mite Neoseiulus californicus (Acari: Phytoseiidae)
- Force perceptual bias caused by muscle activity in unimanual steering
- Correction: Comparison of risk models for mortality and cardiovascular events between machine learning and conventional logistic regression analysis
- Correction: Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium
- Providencia entomophila sp. nov., a new bacterial species associated with major olive pests in Tunisia
- Safety of intravitreal ziv-aflibercept in choroido-retinal vascular diseases: A randomised double-blind intervention study
- A novel framework for evaluating the impact of individual decision-making on public health outcomes and its potential application to study antiviral treatment collection during an influenza pandemic
- Reduction of the rocuronium-induced withdrawal reflex by MR13A10A, a generic rocuronium with a novel solution: A randomized, controlled study
- Emotionally expressed voices are retained in memory following a single exposure
- Megabenthic communities of the Ligurian deep continental shelf and shelf break (NW Mediterranean Sea)
- Election forensics: Using machine learning and synthetic data for possible election anomaly detection
- A randomized crossover trial comparing the Nifty cup to a medicine cup in preterm infants who have difficulty breastfeeding at Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana
- The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease
- Genomic impact of severe population decline in a nomadic songbird
- Evolution of high-sensitivity troponin-T and echocardiography parameters in patients undergoing high efficiency on-line hemodiafiltration versus conventional low-flux hemodialysis
- Full genome characterization of 12 citrus tatter leaf virus isolates for the development of a detection assay
- Intake of myo-inositol hexaphosphate and urinary excretion of inositol phosphates in Wistar rats: Gavage vs. oral administration with sugar
- Enhancing financial security of female sex workers through a community-led intervention in India: Evidence from a longitudinal survey
- In-silico prediction of novel genes responsive to drought and salinity stress tolerance in bread wheat (Triticum aestivum)
- Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
- Partitioning the risk of tuberculosis transmission in household contact studies
- Recommendation system in social networks with topical attention and probabilistic matrix factorization
- Using satellite-measured relative humidity for prediction of Metisa plana’s population in oil palm plantations: A comparative assessment of regression and artificial neural network models
- A drug interaction study investigating the effect of Rifabutin on the pharmacokinetics of Maraviroc in healthy subjects
- Emotional and behavioral problems, social competence and risk factors in 6–16-year-old students in Beijing, China
- Clinicopathologic and prognostic significance of tumor-associated macrophages in patients with hepatocellular carcinoma: A meta-analysis
- Involution of retinopathy of prematurity and neurodevelopmental outcomes after intravitreal bevacizumab treatment
- Travel demand and distance analysis for free-floating car sharing based on deep learning method
- Genome-wide identification, characterization, expression and enzyme activity analysis of coniferyl alcohol acetyltransferase genes involved in eugenol biosynthesis in Prunus mume
- Population analysis of D6-like plasmid prophage variants associated with specific IncC plasmid types in the emerging Salmonella Typhimurium ST213 genotype
- The high resource impact of reformatting requirements for scientific papers
- Egg yolk-free cryopreservation of bull semen
- Fine epitope mapping of glycoprotein Gn in Guertu virus
- Are hospital nurse staffing practices associated with postoperative cardiac events and death? A systematic review
- Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction
- Aging and the wandering brain: Age-related differences in the neural correlates of stimulus-independent thoughts
- Elucidating stygofaunal trophic web interactions via isotopic ecology
- Experimental characterization of two archaeal inosine 5'-monophosphate cyclohydrolases
- Scientist and data architect collaborate to curate and archive an inner ear electrophysiology data collection
- No effect of triple-pulse TMS medial to intraparietal sulcus on online correction for target perturbations during goal-directed hand and foot reaches
- Correction: Controlling Social Stress in Virtual Reality Environments
- TNF-α is responsible for the contribution of stromal cells to osteoclast and odontoclast formation during orthodontic tooth movement
- Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children
- Alteration of humoral, cellular and cytokine immune response to inactivated influenza vaccine in patients with Sickle Cell Disease
- To tweet or not to tweet, that is the question: A randomized trial of Twitter effects in medical education
- Visualizing a field of research: A methodology of systematic scientometric reviews
- True Colors: Commercially-acquired morphological genotypes reveal hidden allele variation among dog breeds, informing both trait ancestry and breed potential
- Impact of the detection of ζ-globin chains and hemoglobin Bart’s using immunochromatographic strip tests for α0-thalassemia (--SEA) differential diagnosis
- Cognitive impairment and medication adherence post-stroke: A five-year follow-up of the ASPIRE-S cohort
- Correction: Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism
- Correction: Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana
- Correction: Precision public health: Mapping socioeconomic disparities in opioid dispensations at Swedish pharmacies by Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA)
- Epidemiological, clinical and laboratory characteristics of the measles resurgence in the Republic of Serbia in 2014-2015
- Macro-charcoal accumulation in floodplain wetlands: Problems and prospects for reconstruction of fire regimes and environmental conditions
- Stage at diagnosis and stage-specific survival of breast cancer in Latin America and the Caribbean: A systematic review and meta-analysis
- Correction: Retraction: Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway
- TEM8/ANTXR1-specific CAR T cells mediate toxicity in vivo
- Clinical impact of intraoperative hyperlactatemia during craniotomy
- Intubation with channeled versus non-channeled video laryngoscopes in simulated difficult airway by junior doctors in an out-of-hospital setting: A crossover manikin study
- Age and growth of stocked juvenile Shoal Bass in a tailwater: Environmental variation and accuracy of daily age estimates
- Sex-specific differences in risk factors of lymph node metastasis in patients with early gastric cancer
- The impact of electroconvulsive therapy on the spatial QRS-T angle and cardiac troponin T concentration in psychiatric patients
- BDNF, NT-3 and Trk receptor agonist monoclonal antibodies promote neuron survival, neurite extension, and synapse restoration in rat cochlea ex vivo models relevant for hidden hearing loss
- Investigation on the hereditary basis of colorectal cancers in an African population with frequent early onset cases
- Comparison of cancer prevalence between patients with glomerulonephritis and the general population at the time of kidney biopsy
- Predictors of time to unfavorable treatment outcomes among patients with multidrug resistant tuberculosis in Oromia region, Ethiopia
- Experimentally validated simulation of coronary stents considering different dogboning ratios and asymmetric stent positioning
- The membrane effects of melittin on gastric and colorectal cancer
- Exclusive breastfeeding policy, practice and influences in South Africa, 1980 to 2018: A mixed-methods systematic review
- Hippocampal subfield volumes and pre-clinical Alzheimer’s disease in 408 cognitively normal adults born in 1946
- Uncorrected low hyperopia in young subjects induces postural instability even in those with clear visual acuity
- Membrane associated proteins of two Trichomonas gallinae clones vary with the virulence
- Awareness, current use of electronic cigarettes and associated smoking factors in Zhejiang Chinese adolescents
- Associations between pre-pregnancy BMI, gestational weight gain, and prenatal diet quality in a national sample
- Effects of continuous ketamine infusion on hemodynamics and mortality in critically ill children
- Optofluidic laser speckle image decorrelation analysis for the assessment of red blood cell storage
- Complete chloroplast genome sequence and phylogenetic analysis of Spathiphyllum 'Parrish'
- Strategic science communication as planned behavior: Understanding scientists’ willingness to choose specific tactics
- Understanding spatial patterns of soils for sustainable agriculture in northern Ethiopia’s tropical mountains
- Does Japan’s national nutrient-based dietary guideline improve lifestyle-related disease outcomes? A retrospective observational cross-sectional study
- Agitation near the end of life with dementia: An ethnographic study of care
- Tick-borne encephalitis virus infections in Germany. Seasonality and in-year patterns. A retrospective analysis from 2001-2018
- Encouraging perspective taking: Using narrative writing to induce empathy for others engaging in negative health behaviors
- Considerations of target surface area and the risk of radiosurgical toxicity
- Correction: A comparative study of RNA-Seq and microarray data analysis on the two examples of rectal-cancer patients and Burkitt Lymphoma cells
- Effect of using immobilization device in fluoroscopic study in pediatric patient: Focused on radiation dose reduction in voiding cystourethrogram
- Temporal trends in breast cancer survival by race and ethnicity: A population-based cohort study
- Contamination of hospital surfaces with respiratory pathogens in Bangladesh
- The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-based oxygen carrier: The cold-to-warm machine perfusion of the liver
- Association between hospital interval and survival in patients with oral cancer: A waiting time paradox
- Translating a stress management intervention for rural Latina breast cancer survivors: The Nuevo Amanecer-II
- Comprehensive management of obstructive sleep apnea by telemedicine: Clinical improvement and cost-effectiveness of a Virtual Sleep Unit. A randomized controlled trial
- Proteomic characterisation of the Chlamydia abortus outer membrane complex (COMC) using combined rapid monolithic column liquid chromatography and fast MS/MS scanning
- Harnessing therapeutic viruses as a delivery vehicle for RNA-based therapy
- Korean soybean core collection: Genotypic and phenotypic diversity population structure and genome-wide association study
- Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study
- Measurement of structural integrity of the spinal cord in patients with amyotrophic lateral sclerosis using diffusion tensor magnetic resonance imaging
- Typological analysis of public-private partnerships in the veterinary domain
- Improved clinical outcome after medial open-wedge osteotomy despite cartilage lesions in the lateral compartment
- Rapid and structure-specific cellular uptake of selected steroids
- Avoiding gambling harm: An evidence-based set of safe gambling practices for consumers
- Epidemiology of chronic pain in Ukraine: Findings from the World Mental Health Survey
- PIAS1 is not suitable as a urothelial carcinoma biomarker protein and pharmacological target
- Double triage to identify poorly annotated genes in maize: The missing link in community curation
- N-acetyl cysteine restores the fertility of vitrified–warmed mouse oocytes derived through ultrasuperovulation
- Architecture of population-differentiated polymorphisms in the human genome
- Linguistic neutrosophic power Muirhead mean operators for safety evaluation of mines
- Extracellular vesicles nanoarray technology: Immobilization of individual extracellular vesicles on nanopatterned polyethylene glycol-lipid conjugate brushes
- Exercise intensity-dependent effects of arm and leg-cycling on cognitive performance
- How information about perpetrators’ nature and nurture influences assessments of their character, mental states, and deserved punishment
- Stringent response governs the oxidative stress resistance and virulence of Francisella tularensis
- In silico assessment of human Calprotectin subunits (S100A8/A9) in presence of sodium and calcium ions using Molecular Dynamics simulation approach
- Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging
- Measurable residual disease monitoring for patients with acute myeloid leukemia following hematopoietic cell transplantation using error corrected hybrid capture next generation sequencing
- Characteristics of complementary medicine therapists in Switzerland: A cross-sectional study
- Lack of generalization between explicit and implicit visuomotor learning
- Diet modulates cecum bacterial diversity and physiological phenotypes across the BXD mouse genetic reference population
- Effects of temperature and salinity on respiratory losses and the ratio of photosynthesis to respiration in representative Antarctic phytoplankton species
- Self-reported non-receipt of HIV test results: A silent barrier to HIV epidemic control in Mozambique
- Plasma midkine concentrations in healthy children, children with increased and decreased adiposity, and children with short stature
- Echocardiography overestimates LV mass in the elderly as compared to cardiac CT
- Efficacy of cotrimoxazole (Sulfamethoxazole-Trimethoprim) as a salvage therapy for the treatment of bone and joint infections (BJIs)
- Molecular mechanism of antimicrobial activity of chlorhexidine against carbapenem-resistant Acinetobacter baumannii
- First identification of the benzimidazole resistance-associated F200Y SNP in the beta-tubulin gene in Ascaris lumbricoides
- Green synthesis of silver nanoparticles using Solanum mammosum L. (Solanaceae) fruit extract and their larvicidal activity against Aedes aegypti L. (Diptera: Culicidae)
- Enterovirus 71 seroepidemiology in Taiwan in 2017 and comparison of those rates in 1997, 1999 and 2007
- Effect of statin on life prognosis in Japanese patients undergoing hemodialysis
- 13C and 15N NMR identification of product compound classes from aqueous and solid phase photodegradation of 2,4,6-trinitrotoluene
- Off-target effects of CRISPRa on interleukin-6 expression
- Exploring the antimicrobial properties of dark-operating ceramic-based nanocomposite materials for the disinfection of indoor air
- Experienced males recognise and avoid mating with non-virgin females in the western flower thrips
- Liver transplantation in patients with a history of migration—A German single center comparative analysis
- Retraction: The Different Role of Notch1 and Notch2 in Astrocytic Gliomas
- Correction: Understanding climate change from a global analysis of city analogues
- Comparison of 4D Flow MRI to 2D Flow MRI in the pulmonary arteries in healthy volunteers and patients with pulmonary hypertension
- The relationship between sleep quality, inappropriate medication use and frailty among older adults in aged care homes in Malaysia
- Clonal diversity and spatial genetic structure in the long-lived herb, Prairie trillium
- Medication histories documentation at the community pharmacy setting: A study from Jordan
- Population dynamics of an invasive bird parasite, Philornis downsi (Diptera: Muscidae), in the Galapagos Islands
- Because you had a bad day: General and daily relations between reactive temperament, emotion regulation, and depressive symptoms in youth
- Socioeconomic status and alcohol use disorders across the lifespan: A co-relative control study
- Generation of deletions and precise point mutations in Dictyostelium discoideum using the CRISPR nickase
- Polymorphisms in vasoactive eicosanoid genes of kidney donors affect biopsy scores and clinical outcomes in renal transplantation
- Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma: A preclinical F98 glioblastoma rat model study
- Validation and perception of a key feature problem examination in neurology
- Gender affirmative HIV care framework: Decisions on feminizing hormone therapy (FHT) and antiretroviral therapy (ART) among transgender women
- Quantifying international human mobility patterns using Facebook Network data
- Localization and characterization of thyroid microcalcifications: A histopathological study
- Young children are the main victims of fast food induced obesity in Brazil
- Understanding self-reported importance of religion/spirituality in a North American sample of individuals at risk for familial depression: A principal component analysis
- Standing balance of professional ballet dancers and non-dancers under different conditions
- 30-day unplanned readmission rate in otolaryngology patients: A population-based study in Thuringia, Germany
- Physical exercise stimulates salivary secretion of cystatins
- Vintage electronics for trusted radiation measurements and verified dismantlement of nuclear weapons
- Keepin’ it real: Linguistic models of authenticity judgments for artificially generated rap lyrics
- Carbon emission reduction and profit distribution mechanism of construction supply chain with fairness concern and cap-and-trade
- Modulations of microbehaviour by associative memory strength in Drosophila larvae
- Changes in peak expiratory flow rates using two head-tilt/chin-lift maneuver angles in young healthy conscious volunteers
- 3D image analysis reveals differences of CD30 positive cells and network formation in reactive and malignant human lymphoid tissue (classical Hodgkin Lymphoma)
- Change in larval fish assemblage in a USA east coast estuary estimated from twenty-six years of fixed weekly sampling
- 2-methylquinazoline derivative F7 as a potent and selective HDAC6 inhibitor protected against rhabdomyolysis-induced acute kidney injury
- Correction: Reducing growth and developmental problems in children: Development of an innovative postnatal risk assessment
- Comparative analysis of the vertebral pneumatization in pterosaurs (Reptilia: Pterosauria) and extant birds (Avialae: Neornithes)
- Associations between cognitive performance and sigma power during sleep in children with attention-deficit/hyperactivity disorder, healthy children, and healthy adults
- Retraction: MiR-375 Is Epigenetically Downregulated by HPV-16 E6 Mediated DNMT1 Upregulation and Modulates EMT of Cervical Cancer Cells by Suppressing lncRNA MALAT1
- Comparing growth patterns of three species: Similarities and differences
- Iron is increased in the brains of ageing mice lacking the neurofilament light gene
- Economic evaluation of community acquired pneumonia management strategies: A systematic review of literature
- A participatory community case study of periurban coastal flood vulnerability in southern Ecuador
- Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL
- Mitochondrial dysfunctions in leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL)
- MRI-based visualization of rTMS-induced cortical plasticity in the primary motor cortex
- Knowledge, attitudes, and practices related to anthrax and animal care: A case-control study in Georgia
- Information diffusion in signed networks
- Nurses’ perspectives on their communication with patients in busy oncology wards: A qualitative study
- Inflammation in acute coronary syndrome: Expression of TLR2 mRNA is increased in platelets of patients with ACS
- ART is key to clearing oncogenic HPV genotypes (HR-HPV) in anal mucosa of HIV-positive MSM
- Retraction: Fluid–Structure Interaction-Based Biomechanical Perception Model for Tactile Sensing
- Correction: Role of Caveolin-1 in Atrial Fibrillation as an Anti-Fibrotic Signaling Molecule in Human Atrial Fibroblasts
- The French adaptation and validation of the Partners in Health (PIH) scale among patients with chronic conditions seen in primary care
- Depth inversion with a 3D structure influences brightness perception
- Analysis of group evolution prediction in complex networks
- Effect of aridity and dune type on rhizosphere soil bacterial communities of Caragana microphylla in desert regions of northern China
- Knowledge, attitudes, and practices related to TB among the general population of Ethiopia: Findings from a national cross-sectional survey
- Correction: Personality traits in companion dogs—Results from the VIDOPET
- MANET 3.0: Hierarchy and modularity in evolving metabolic networks
- Agreement study on gait assessment using a video-assisted rating method in patients with idiopathic normal-pressure hydrocephalus
- Single fixed low-dose rituximab as induction therapy suppresses de novo donor-specific anti-HLA antibody production in ABO compatible living kidney transplant recipients
- Myomesin is part of an integrity pathway that responds to sarcomere damage and disease
- Acute normobaric hypoxia does not affect the simultaneous exercise-induced increase in circulating BDNF and GDNF in young healthy men: A feasibility study
- Systematic investigation on quad-metallic AgAuPdPt and tri-metallic AuPdPt NPs through the solid-state dewetting of quad-layer Ag/Au/Pd/Pt thin films on c-plane sapphire
- Video lecturing in Clicker-assisted English flipped class
- Significant changes of the choroid in patients with ocular ischemic syndrome and symptomatic carotid artery stenosis
- Skewed T cell responses to Epstein-Barr virus in long-term asymptomatic kidney transplant recipients
- Candidate genes expression profiling during wilting in chickpea caused by Fusarium oxysporum f. sp. ciceris race 5
- Host plants influence the composition of the gut bacteria in Henosepilachna vigintioctopunctata
- ‘We are all serving the same Ugandans’: A nationwide mixed-methods evaluation of private sector surgical capacity in Uganda
- The association between flavor capsule cigarette use and sociodemographic variables: Evidence from Chile
- Relations between gross motor skills and executive functions, controlling for the role of information processing and lapses of attention in 8-10 year old children
- Linalool acts as a fast and reversible anesthetic in Hydra
- Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka
- Using isotemporal substitution to predict the effects of changing physical behaviour on older adults’ cardio-metabolic profiles
- Adherence to general medical checkup and cancer screening guidelines according to self-reported smoking status: Korea National Health and Nutrition Examination Survey (KNHANES) 2010–2012
- Do older English adults exhibit day-to-day compensation in sedentary time and in prolonged sedentary bouts? An EPIC-Norfolk cohort analysis
- Linoleic acid supplementation of cell culture media influences the phospholipid and lipid profiles of human reconstructed adipose tissue
- Correction: Factors associated with hospitalization and death among TB/HIV co-infected persons in Porto Alegre, Brazil
- An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
- Reporting adverse events related to medical devices: A single center experience from a tertiary academic hospital
- Enterohemorrhagic Escherichia coli infection inhibits colonic thiamin pyrophosphate uptake via transcriptional mechanism
- Estimating biodiversity changes in the Camargue wetlands: An expert knowledge approach
- Decreased risk of Parkinson’s disease in diabetic patients with thiazolidinediones therapy: An exploratory meta-analysis
- Retraction: Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis
- Lipoarabinomannan from Mycobacterium indicus pranii shows immunostimulatory activity and induces autophagy in macrophages
- A measure of inconsistencies in intertemporal choice
- A novel radiopaque tissue marker for soft tissue localization and in vivo length and area measurements
- Anatomical, histological and computed tomography comparisons of the eye and adnexa of crab-eating fox (Cerdocyon thous) to domestic dogs
- Subpopulation augmentation among habitat patches as a tool to manage an endangered Mojave Desert wetlands-dependent rodent during anthropogenic restricted water climate regimes
- Characteristics of CD5-positive diffuse large B-cell lymphoma among Koreans: High incidence of BCL2 and MYC double-expressors
- Fossil tabulate corals reveal outcrops of Paleozoic sandstones in the Atlantic Coastal Plain Province, Southeastern USA
- Coming and going – Historical distributions of the European oyster Ostrea edulis Linnaeus, 1758 and the introduced slipper limpet Crepidula fornicata Linnaeus, 1758 in the North Sea
- Behavioral predictors of subsequent respiratory illness signs in dogs admitted to an animal shelter
- Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation
- Can emotional intelligence be improved? A randomized experimental study of a business-oriented EI training program for senior managers
- Genetic variability in landraces populations and the risk to lose genetic variation. The example of landrace ‘Kyperounda’ and its implications for ex situ conservation
- Sleep problems are a strong predictor of stress-related metabolic changes in police officers. A prospective study
- Age, sex and primary care setting differences in patients’ perception of community healthcare seeking behaviour towards health services
- Kinematic analyses including finite helical axes of drop jump landings demonstrate decreased knee control long after anterior cruciate ligament injury
- Effects of model inaccuracies on reaching movements with intermittent control
- C-reactive protein to albumin ratio predicts the outcome in renal cell carcinoma: A meta-analysis
- A new synthetic lure for management of the invasive giant African snail, Lissachatina fulica
- Bridging solvent molecules mediate RNase A – Ligand binding
- Variation in methods, results and reporting in electronic health record-based studies evaluating routine care in gout: A systematic review
- The use of prophylactic intra-aortic balloon pump in high-risk patients undergoing coronary artery bypass grafting
- Compliance with clinical guidelines for breast cancer management: A population-based study of quality-of-care indicators in France
- Dysregulated T helper type 1 (Th1) and Th17 responses in elderly hospitalised patients with infection and sepsis
- Acute effects of differential learning on football kicking performance and in countermovement jump
- Escherichia coli and Salmonella spp. isolated from Australian meat chickens remain susceptible to critically important antimicrobial agents
- Play like me: Similarity in playfulness promotes social play
- Awareness of family health history in a predominantly young adult population
- Care pathways during a child’s final illness in rural South Africa: Findings from a social autopsy study
- Intranasal lidocaine for acute migraine: A meta-analysis of randomized controlled trials
- Evaluating case management as a complex intervention: Lessons for the future
- Allele-specific enhancer interaction at the Peg3 imprinted domain
- Has the “M” word been framed? Marijuana, cannabis, and public opinion
- Is spontaneous normalization of systolic blood pressure within 24 hours after ischemic stroke onset related with favorable outcomes?
- Mixotrophic cultivation of Spirulina platensis in dairy wastewater: Effects on the production of biomass, biochemical composition and antioxidant capacity
- Constitutive expression of an A-5 subgroup member in the DREB transcription factor subfamily from Ammopiptanthus mongolicus enhanced abiotic stress tolerance and anthocyanin accumulation in transgenic Arabidopsis
- Stable carbon isotope diagnostics of mammalian metabolism, a high-resolution isotomics approach using amino acid carboxyl groups
- Factors associated with depressive symptoms in patients with ankylosing spondylitis in Northern Taiwan
- A multicenter prospective study of 515 febrile neutropenia episodes in Argentina during a 5-year period
- Retraction: Reversal Effect of ST6GAL 1 on Multidrug Resistance in Human Leukemia by Regulating the PI3K/Akt Pathway and the Expression of P-gp and MRP1
- Potential role for microRNA-16 (miR-16) and microRNA-93 (miR-93) in diagnosis and prediction of disease progression in mycosis fungoides in Egyptian patients
- Rapid visual categorization is not guided by early salience-based selection
- Relative contribution of climate and non-climate drivers in determining dynamic rates of boreal birds at the edge of their range
- A simple-to-use nomogram to predict long term survival of patients undergoing coronary artery bypass grafting (CABG) using bilateral internal thoracic artery grafting technique
- Effects of sonication parameters on transcranial focused ultrasound brain stimulation in an ovine model
- Antenatal and intrapartum interventions for reducing caesarean section, promoting vaginal birth, and reducing fear of childbirth: An overview of systematic reviews
- Relative species abundance successfully predicts nestedness and interaction frequency of monthly pollination networks in an alpine meadow
- Correction: RCER: Reliable Cluster-based Energy-aware Routing protocol for heterogeneous Wireless Sensor Networks
- Amphibians on the hotspot: Molecular biology and conservation in the South American Atlantic Rainforest
- Role of psychosocial status in predicting health-related quality of life at 1-year follow-up among newly diagnosed people living with HIV
- Application of national pollutant inventories for monitoring trends on dioxin emissions from stationary industrial sources in Australia, Canada and European Union
- The association between vaccination confidence, vaccination behavior, and willingness to recommend vaccines among Finnish healthcare workers
- Retraction: Interleukin-1β-Induced Autophagy-Related Gene 5 Regulates Proliferation of Embryonic Stem Cell-Derived Odontoblastic Cells
- A localized sanitation status index as a proxy for fecal contamination in urban Maputo, Mozambique
- E2 protein is the major determinant of specificity at the human papillomavirus origin of replication
- “You’re kind of at war with yourself as a nurse”: Perspectives of inpatient nurses on treating people who present with a comorbid opioid use disorder
- A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury
- Circulating cell-free DNA from plasma undergoes less fragmentation during bisulfite treatment than genomic DNA due to low molecular weight
- Understanding fatigue in adults with visual impairment: A path analysis study of sociodemographic, psychological and health-related factors
- Retraction: Mouse-Induced Pluripotent Stem Cells Differentiate into Odontoblast-Like Cells with Induction of Altered Adhesive and Migratory Phenotype of Integrin
- A novel analytical method to assess the effect of imipenem/cilastatin on liver function laboratory indexes in Chinese underage inpatients: Probability distribution curve
- The cause of anorexia and proportion of its recovery in older adults without underlying disease: Results of a retrospective study
- Referral and admission to intensive care: A qualitative study of doctors’ practices in a Tanzanian university hospital
- Agreement between clinical and non-clinical digital manometer for assessing maximal respiratory pressures in healthy subjects
- Heads or tails? Differential translational regulation in cercarial heads and tails of schistosome worms
- Horizontal seed dispersal by dung beetles reduced seed and seedling clumping, but did not increase short-term seedling establishment
- The coupling of the M2 muscarinic receptor to its G protein is voltage dependent
- Subsidy strategy of pharmaceutical e-commerce platform based on two-sided market theory
- Shoulder girdle injuries involving the medial clavicle differ from lateral clavicle injuries with a focus on concomitant injuries and management strategies: A retrospective study based on nationwide routine data
- Unraveling middle childhood attachment-related behavior sequences using a micro-coding approach
- Divergence history and hydrothermal vent adaptation of decapod crustaceans: A mitogenomic perspective
- Duration of solid fuel cookstove use is associated with increased risk of acute lower respiratory infection among children under six months in rural central India
- Evolving flocking in embodied agents based on local and global application of Reynolds’ rules
- Non-invasive contrast enhanced ultrasound molecular imaging of inflammation in autoimmune myocarditis for prediction of left ventricular fibrosis and remodeling
- Care coordination for chronic and complex health conditions: An experienced based co-design study engaging consumer and clinician groups for service improvement
- Association between socioeconomic status and diet quality in Mexican men and women: A cross-sectional study
- Surveillance of panicle positions by unmanned aerial vehicle to reveal morphological features of rice
- Is Betula carpatica genetically distinctive? A morphometric, cytometric and molecular study of birches in the Bohemian Massif with a focus on Carpathian birch
- Correction: Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance
- The genome of the migratory nematode, Radopholus similis, reveals signatures of close association to the sedentary cyst nematodes
- Factors associated with pneumococcal carriage and density in infants and young children in Laos PDR
- Overlap between telangiectasia and photoreceptor loss increases with progression of macular telangiectasia type 2
- The role of hope for health professionals in rehabilitation: A qualitative study on unfavorable prognosis communication
- Expression of miR-34a-5p is up-regulated in human colorectal cancer and correlates with survival and clock gene PER2 expression
- Molecular characterization and In Vitro synthesis of infectious RNA of a Turnip vein-clearing virus isolated from Alliaria petiolata in Hungary
- Assessment of client satisfaction with pharmacist services at outpatient pharmacy of Tikur Anbessa Specialized Hospital
- Thermogravimetric analysis of the co-combustion of coal and polyvinyl chloride
- Roles of leptin in the recovery of muscle and bone by reloading after mechanical unloading in high fat diet-fed obese mice
- Unexpected high seroprevalence of hepatitis E virus in patients with alcohol-related cirrhosis
- APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy
- Integrating a gait analysis test in hospital rehabilitation: A service design approach
- Correction: Bioactivity-guided isolation of rosmarinic acid as the principle bioactive compound from the butanol extract of Isodon rugosus against the pea aphid, Acyrthosiphon pisum
- Soil-borne fungi influence seed germination and mortality, with implications for coexistence of desert winter annual plants
- Applying Corrigan’s progressive model of self-stigma to people with depression
- Do psychosocial factors modify the negative association between disability and life satisfaction in old age?
- Public perception of coastal habitat loss and habitat creation using artificial floating islands in the UK
- Transcriptional foliar profile of the C3-CAM bromeliad Guzmania monostachia
- Application of tuned liquid column ball damper (TLCBD) for improved vibration control performance of multi-storey structure
- Do protection gradients explain patterns in herbivore densities? An example with ungulates in Zambia’s Luangwa Valley
- Consequences of chronic bacterial infection in Drosophila melanogaster
- The effects of environmental parameters on the microbial activity in peat-bog lakes
- Differences in protein structural regions that impact functional specificity in GT2 family β-glucan synthases
- Correction: Identification of lysine methylation in the core GTPase domain by GoMADScan
- Changes of absorbed dose rate in air in metropolitan Tokyo relating to radiocesium released from the Fukushima Daiichi Nuclear Power Plant accident: Results of a five-year study
- Histological chorioamnionitis, antenatal steroids, and neonatal outcomes in very low birth weight infants: A nationwide study
- A machine learning approach for the prediction of pulmonary hypertension
- Altered microbiota, fecal lactate, and fecal bile acids in dogs with gastrointestinal disease
- Impaired processing of threat in psychopathy: A systematic review and meta-analysis of factorial data in male offender populations
- Dimethyl disulfide (DMDS) as an effective soil fumigant against nematodes in China
- Risk factors for hepatitis C infection among adult patients in Kedah state, Malaysia: A case–control study
- Factoring a 2 x 2 contingency table
- The development of connectives in three to five-year-old monolingual Spanish-speaking children
- Foliar plasticity related to gradients of heat and drought stress across crown orientations in three Mediterranean Quercus species
- The evolution of haploid chromosome numbers in Meliponini
- Bloodstream infections caused by Escherichia coli in onco-haematological patients: Risk factors and mortality in an Italian prospective survey
- Facial features and unethical behavior – Doped athletes show higher facial width-to-height ratios than non-doping sanctioned athletes
- Non-resolution of non-alcoholic fatty liver disease (NAFLD) among urban, adult Sri Lankans in the general population: A prospective, cohort follow-up study
- Left ventricular simulation of cardiac compression: Hemodynamics and regional mechanics
- Are we ready for scaling up restoration actions? An insight from Mediterranean macroalgal canopies
- Age-related changes in size, bone microarchitecture and volumetric bone mineral density of the mandible in the harbor seal (Phoca vitulina)
- Parasitism modifies the direct effects of warming on a hemiparasite and its host
- Analytic performance of PANArray HPV and HPV 9G DNA chip tests for genotyping of high-risk human papillomavirus in cervical ThinPrep PreservCyt samples
- Transcript profile of skeletal muscle lipid metabolism genes affected by diet in a piglet model of low birth weight
- Differential impact of smoking on cardiac or non-cardiac death according to age
- Influence of injectate volume on paravertebral spread in erector spinae plane block: An endoscopic and anatomical evaluation
- Correction: Nitrogen starvation induces distinct photosynthetic responses and recovery dynamics in diatoms and prasinophytes
- Healthcare needs and programmatic gaps in transition from pediatric to adult care of vertically transmitted HIV infected adolescents in India
- Retraction: Neuronal Differentiation Dictates Estrogen-Dependent Survival and ERK1/2 Kinetic by Means of Caveolin-1
- Correction: Disability and its association with sociodemographic factors among elderly persons residing in an urban resettlement colony, New Delhi, India
- Antibacterial activity of varying UMF-graded Manuka honeys
- Correction: Synthesis of IL-6 by Hepatocytes Is a Normal Response to Common Hepatic Stimuli
- Detection and genetic characterization of Echinococcus granulosus mitochondrial DNA in serum and formalin-fixed paraffin embedded cyst tissue samples of cystic echinococcosis patients
- Deep-learning-based risk stratification for mortality of patients with acute myocardial infarction
- Links between meaning in life and physical quality of life after rehabilitation: Mediating effects of positive experiences with physical exercises and mobility
- The estrogen effect; clinical and histopathological evidence of dichotomous influences in dogs with spontaneous mammary carcinomas
- The association between socioeconomic status, psychopathological symptom burden in mothers, and early childhood caries of their children
- Increased rate of FEV1 decline in HIV patients despite effective treatment with HAART
- Parallels between stream and coastal water quality associated with groundwater discharge
- Determinants of anemia among pregnant women attending antenatal care in Horo Guduru Wollega Zone, West Ethiopia: Unmatched case-control study
- Depression and anxiety among pregnant women living with HIV in Kilimanjaro region, Tanzania
- Shift in trophic niches of soil microarthropods with conversion of tropical rainforest into plantations as indicated by stable isotopes (15N, 13C)
- On the development of sleep states in the first weeks of life
- CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro
- Investigation into pathophysiology of naturally occurring palatal instability and intermittent dorsal displacement of the soft palate (DDSP) in racehorses: Thyro-hyoid muscles fatigue during exercise
- Correction: Reducing phenolic off-flavors through CRISPR-based gene editing of the FDC1 gene in Saccharomyces cerevisiae x Saccharomyces eubayanus hybrid lager beer yeasts
- MitoToxy assay: A novel cell-based method for the assessment of metabolic toxicity in a multiwell plate format using a lactate FRET nanosensor, Laconic
- Correction: Evidence for plant-derived xenomiRs based on a large-scale analysis of public small RNA sequencing data from human samples
- Correction: Prognostic impact of systolic blood pressure variability in people with diabetes
- Retraction: Sialoglycosylation of RBC in Visceral Leishmaniasis Leads to Enhanced Oxidative Stress, Calpain-Induced Fragmentation of Spectrin and Hemolysis
- Too much? Mortality and health service utilisation among Danish children 1999-2016: A register-based study
- Effects of sodium-glucose cotransporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors on diabetic retinopathy and its progression: A real-world Korean study
- Shipworm bioerosion of lithic substrates in a freshwater setting, Abatan River, Philippines: Ichnologic, paleoenvironmental and biogeomorphical implications
- Genetic codes optimized as a traveling salesman problem
- Effect of antenatal detection of small-for-gestational-age newborns in a risk stratified retrospective cohort
- Using family network data in child protection services
- Transcriptome sequencing reveals the effect of biochar improvement on the development of tobacco plants before and after topping
- Volatile anesthetics versus total intravenous anesthesia in patients undergoing coronary artery bypass grafting: An updated meta-analysis and trial sequential analysis of randomized controlled trials
- Cumulative fluid balance predicts mortality and increases time on mechanical ventilation in ARDS patients: An observational cohort study
- Stated-preference research in HIV: A scoping review
- Correction: Survival of infants ≤24 months of age with brain tumors: A population-based study using the SEER database
- Antinociceptive compounds and LC-DAD-ESIMSn profile from Dictyoloma vandellianum leaves
- Time series experimental design under one-shot sampling: The importance of condition diversity
- Evaluation of protocols for rRNA depletion-based RNA sequencing of nanogram inputs of mammalian total RNA
- Prevalence and predictors of primary postpartum hemorrhage: An implication for designing effective intervention at selected hospitals, Southern Ethiopia
- Correction: Stillbirths in urban Guinea-Bissau: A hospital- and community-based study
- Correction: Method for spike detection from microelectrode array recordings contaminated by artifacts of simultaneous two-photon imaging
- Correction: Peripheral blood mononuclear cells extracts VEGF protein levels and VEGF mRNA: Associations with inflammatory molecules in a healthy population
- Correction: Novel site-specific PEGylated L-asparaginase
- Effect of caffeine ingestion on competitive rifle shooting performance
- Correction: Color adaptation induced from linguistic description of color
- MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity
- Correction: A biface production older than 600 ka ago at Notarchirico (Southern Italy) contribution to understanding early Acheulean cognition and skills in Europe
- Correction: A urinary extracellular vesicle microRNA biomarker discovery pipeline; from automated extracellular vesicle enrichment by acoustic trapping to microRNA sequencing
- Measurement of horizontal ocular deviation on magnetic resonance imaging in various disease with acute vertigo
- Clinical outcomes of early gastric cancer with non-curative resection after pathological evaluation based on the expanded criteria
- Detection of quantitative trait loci associated with drought tolerance in St. Augustinegrass
- An examination of the Kuleshov effect using still photographs
- Correction: Relationship between non-communicable diseases and background characteristics among homeless people in Nagoya City, Japan
- An exploration of automated narrative analysis via machine learning
- Correction: Frozen by stress: Stress increases scope insensitivity
- The pragmatic role of trust in young children’s interpretation of unfamiliar signals
- Measuring egocentric distance perception in virtual reality: Influence of methodologies, locomotion and translation gains
- Mathematical modeling of cardiac function to evaluate clinical cases in adults and children
- Correction: Forecasting the impact of population ageing on tuberculosis incidence
- “The car is my extra legs” – Experiences of outdoor mobility amongst immigrants in Sweden with late effects of polio
- Correction: Multilevel analyses of on-demand medication data, with an application to the treatment of Female Sexual Interest/Arousal Disorder
- Correction: The world’s user-generated road map is more than 80% complete
- Correction: Predictors of opioid efficacy in patients with chronic pain: A prospective multicenter observational cohort study
- Correction: Comparative prognostic accuracy of sepsis scores for hospital mortality in adults with suspected infection in non-ICU and ICU at an academic public hospital
- Correction: Biosynthesis of the oxygenated diterpene nezukol in the medicinal plant Isodon rubescens is catalyzed by a pair of diterpene synthases
- Correction: Effect of early measles vaccine on pneumococcal colonization: A randomized trial from Guinea-Bissau
- Correction: Tuberculosis patients in an Indian mega-city: Where do they live and where are they diagnosed?
- Correction: Priority Queue Based Reactive Buffer Management Policy for Delay Tolerant Network under City Based Environments
- Correction: Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma
- Correction: A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas
- Correction: Evolution and study of a copycat effect in intimate partner homicides: A lesson from Spanish femicides
- Correction: Transforming growth factor beta 1 induces methylation changes in lung fibroblasts
- Correction: Congenital Zika Syndrome in a Brazil-Paraguay-Bolivia border region: Clinical features of cases diagnosed between 2015 and 2018
- Correction: Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression
- Correction: Factors influencing the behaviour and perceptions of Australian veterinarians towards antibiotic use and antimicrobial resistance
- Correction: Nonalcoholic fatty liver disease is a risk factor for large-for-gestational-age birthweight
- Retraction: Butyrate Attenuates Lipopolysaccharide-Induced Inflammation in Intestinal Cells and Crohn's Mucosa through Modulation of Antioxidant Defense Machinery
- Retraction: Tetrandrine Suppresses Lipopolysaccharide-Induced Microglial Activation by Inhibiting NF-κB and ERK Signaling Pathways in BV2 Cells
- Correction: Isolation of five Enterobacteriaceae species harbouring blaNDM-1 and mcr-1 plasmids from a single paediatric patient
- Correction: Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents
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