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ReklamaA multidimensional understanding of prosperity and well-being at country level: Data-driven explorations
Authors: Mohsen Joshanloo aff001; Veljko Jovanović aff002; Tim Taylor aff003
Authors place of work: Department of Psychology, Keimyung University, Daegu, South Korea aff001; Department of Psychology, Faculty of Philosophy, University of Novi Sad, Novi Sad, Serbia aff002; Interdisciplinary Ethics Applied Centre, University of Leeds, Holmfirth, England, United Kingdom aff003
Published in the journal: PLoS ONE 14(10)
Category: Research Article
doi: https://doi.org/10.1371/journal.pone.0223221Summary
Social scientists have been interested in measuring the prosperity, well-being, and quality of life of nations, which has resulted in a multiplicity of country-level indicators. However, little is known about the factor structure of these indicators. We explored the structure of quality of life, using country-level data on tens of subjective and objective indicators. Applying factor analysis, we identified three distinct factors that exhibited both overlap and complementarity. This structure was replicated in data from previous years and with a partially different set of variables. The first factor, ‘socio-economic progress’, is dominated by socio-political and economic indicators but also includes life satisfaction, which thus appears to reflect objective living conditions. The second factor, ‘psycho-social functioning’, consists of subjective indicators, such as eudaimonic well-being and positive affective states. The third, ‘negative affectivity’, comprises negatively-valenced affective states. The three macro-factors of societal quality of life demonstrated moderate intercorrelations and differential associations with cultural and ecological variables, providing support for their discriminant validity. Finally, country and regional rankings based on the three societal factors revealed a complex picture that cautions against over-reliance on any single indicator such as life satisfaction. The results underline the need for a broadly-based approach to the measurement of societal quality of life, and provide an empirically-derived multidimensional framework for conceptualizing and measuring quality of life and well-being at country level. This study is thus an initial empirical step towards systematizing the multiple approaches to societal quality of life.
Keywords:
Quality of life – Mental health and psychiatry – Health education and awareness – Behavioral and social aspects of health – Factor analysis – suicide – Global health – Happiness
Introduction
Well-being is an elusive construct, which defies easy and unambiguous definition. Understanding the nature and structure of well-being has been one of the challenging tasks in social science research and philosophy. At the philosophical level, there are several rival theories which make competing claims about what well-being consists in [1]. In empirical research too, a number of operationalizations, conceptualizations, and definitions of the well-being construct have been proposed across disciplines [2, 3]. We are well past the era when traditional income-based economic indicators were considered sufficient indicators of societal well-being. Humanistic and social measures (e.g., health, education, and social capital) are increasingly emphasized and incorporated in empirical research on well-being [4]. This multiplicity of theory may lead to a major challenge by hampering consensus in conceptualizing well-being both at the individual and societal levels. Yet, this multiplicity also provides a diverse dashboard of operationalizations and approaches to enable a comprehensive understanding of the complex construct of well-being while avoiding reductive and simplistic approaches [5].
We take an empirically oriented and pluralistic approach to provide an integrative and multidimensional framework for conceptualizing and appraising quality of life, prosperity, and well-being at societal level. In doing so, we bring together a relatively comprehensive array of indicators of societal quality of life which has never before been collectively investigated in a single study. Our wide-ranging suite of indicators covers subjective and objective, as well as hedonic and eudaimonic aspects of quality of life. Our results suggest that the variables group into overlapping and supplementary dimensions. We believe this empirically-based categorization of the indicators has the potential to add new depth and insight to our understanding of prosperity and well-being at the societal level.
Measurement of societal well-being
Gaining insight into the nature of societal well-being (or quality of life, prosperity, and societal progress and development) has been inextricably linked with the question of how to measure this construct. The construct has traditionally been measured using economic indicators such as national income per capita and gross domestic product (GDP) per capita [6]. However, in recent years the inadequacy of economic indicators as proxies of well-being has been widely recognized and discussed (for an overview, see [7]). A number of non-economic dimensions of well-being had been systematically proposed, initially within the social indicators movement in the late 1960s and 1970s, to supplement economic measures as indicators of a country’s prosperity and progress [8].
Beyond the academic sphere, governments and international organizations too have increasingly recognized the need to go beyond economic measures. The UK, for example, instituted a programme entitled Measuring National Well-being, using a wide range of well-being measures, following the then Prime Minister, David Cameron’s 2010 declaration of intent to measure national progress ‘not merely by standard of living, but by quality of life’. Similarly, France has introduced quality of life measures in response to the findings of a Commission on the Measurement of Economic Performance and Social Progress [9]. Other developed countries, and international bodies such as the European Union (‘GDP and Beyond’) and the OECD (the Better Life Index) have introduced similar initiatives [10].
The predominant view in modern well-being research is that societal well-being is essentially a complex, multidimensional construct, including both objective and subjective indicators, and accordingly a comprehensive assessment of well-being must also capture both these aspects [11, 12]. The objective approach, originating in economics, focuses on material resources and objective indicators as proxies for well-being, whereas the subjective approach, originating from social survey research and psychology, concerns how individuals experience their lives and focuses on subjective evaluations of life and individuals’ inner feelings [13, 14]. The multidimensional approach to human well-being still needs to answer the question of which dimensions should be included in the conceptualization of well-being. This problem is especially evident regarding subjective indicators, due to a variety of well-being models developed in psychology over the past few decades. In general, well-being models in psychology take one (or both) of two relatively distinct, yet overlapping approaches to human well-being: the hedonic (or subjective) perspective and the eudaimonic perspective [15–17], which are discussed below.
Hedonic/Subjective well-being
The hedonic perspective on well-being emphasizes the cognitive and affective evaluations of one’s life, and is usually operationalized as subjective well-being (SWB), which includes positive affect, negative affect, and overall life satisfaction [18]. Probably the most widely used and reported SWB indicator has been life satisfaction, which is increasingly being promoted as an alternative measure of well-being to inform public policy [19]. Consequently, most large-scale surveys of quality of life include a single-item (or longer) scale of life satisfaction as a key measure of well-being. Outside the realm of empirical social science, some philosophical theories define well-being in terms of life satisfaction [20]. Life satisfaction’s attractiveness to those who favor a simple metric of well-being can be explained by the fact that, even if it is not regarded as definitive of well-being in its own right, it can be seen as equivalent to a person’s own assessment of their well-being, taking into account other aspects [1]. Thus, while most individual measures can only plausibly capture part of the picture regarding well-being, life satisfaction has a reasonable claim to be an indicator of a person’s overall well-being.
Reliance on life-satisfaction as the sole measure of well-being rests on two assumptions: a) that a score on a life-satisfaction scale accurately reflects a person’s assessment of their own well-being; and b) that a person is a reliable judge of their own well-being. Both of these assumptions are open to question. There is evidence that life-satisfaction scores (and indeed, other SWB measures) adapt to circumstances, an effect first identified by Brickman, Coates, and Janoff-Bulman [21], and are susceptible to a variety of influences which are arguably unrelated to well-being, such as social comparisons [22] and ethical norms [23]. There is considerable debate about the extent to which these effects undermine subjective well-being measures, if at all [24, 25].
In measuring well-being some authors have exclusively focused on subjective indicators. For example, the Australian Unity Well-Being Index measures well-being by merely assessing satisfaction across several aspects of life [26]. SWB, particularly life satisfaction, has been advocated by some researchers as the gold-standard measure for assessing well-being [27]. However, many researchers have criticized this approach as arbitrary, simplistic, and reductive [5, 28]. Diener, Inglehart, and Tay [29] point out that “… life satisfaction measures have clear limits, and provide only one type of information to policymakers.” (pp. 521–522). In her review of societal well-being variables, Delle Fave [30] concludes that “there is no consensus on which subjective variables could be the ideal and most reliable indicators of well-being” (p. 85). In the present article, we take the view that, whilst life satisfaction remains a useful measure of well-being, it would be unwise to rely solely upon this single measure and that a broader mix of subjective and objective measures is more appropriate to measure national well-being and quality of life. In fact, there is increasing recognition of the need to integrate hedonic and eudaimonic approaches to well-being rather than relying solely on one and dismissing the other [15, 31].
Eudaimonic well-being
Eudaimonic well-being concerns psychological and social qualities that make a life worth living [32]. Most definitions of eudaimonic well-being exclude emotional components and instead focus on the fulfillment of human potential, psycho-social skills, a meaningful life, and self-actualization [33, 34]. Ryff’s [35] model of psychological well-being, which includes six key dimensions of autonomy, personal growth, self-acceptance, purpose in life, environmental mastery, and positive relationships, seems to be currently the most dominant in the field of eudaimonic well-being at the individual level of analysis. Other eudaimonic models posit highly similar qualities and skills [36].
The majority of previous global studies on well-being and discussions on the policy implications of well-being have focused on SWB indicators, especially life satisfaction [37]. Eudaimonic well-being measures have been rarely used in global well-being studies and largely ignored in debates on public policy. This seems to be largely due to the fact that comparable multinational data on eudaimonic well-being are only recently beginning to emerge. Huppert and So [31], provided a preliminary examination of eudaimonic well-being based on the data collected in the sixth round of the European Social Survey in 29 European countries. Joshanloo [33] developed a new index of eudaimonic well-being across 166 countries (capturing learning experience, social support, respect, efficacy beliefs, sense of freedom, and pro-sociality), which makes global studies of eudaimonic well-being possible. Individual-level studies suggest that hedonic and eudaimonic aspects are related, yet distinct components of mental well-being [16]. Joshanloo’s [33] results replicate this finding at the societal level. Thus, there is a strong case for including these both hedonic and eudaimonic aspects in holistic models of well-being since they capture different components of human well-being [38] and have differential relationships with other variables [39].
Measurement of societal well-being
Although most studies of well-being have focused on individual differences, the assessment of well-being at the country level has also flourished over the past few decades [40]. Although it is a widely researched topic in recent years, there is no consensus about the conceptualization and measurement of societal well-being. Different organizations and authors across various fields have proposed an array of dimensions and composite indicators in order to measure progress towards valuable goals and to enable informative and meaningful cross-country comparison [41].
One of the first attempts to measure material and social prosperity via multiple dimensions was made by the United Nations Development Programme (UNDP), when it introduced the Human Development Index (HDI) in 1990. The HDI is probably the best known composite well-being index, capturing three dimensions: longevity, education, and income. However, the HDI has received some criticisms (for an overview, see [42]); the main criticism being its narrow definition of well-being and the inclusion of too few dimensions. Thus, a number of alternative approaches to the measurement of prosperity and well-being at the national level have been developed in recent years, in order to capture additional relevant aspects of human well-being not included in the HDI. For example, in an effort to select and study quality of life variable in a systematic way, Diener [43] developed a value-based index of societal quality of life, where variables selected for measuring quality of life are reflective of prominent values endorsed across societies. This value-based index of quality of life is grounded on the universal structure of values constructed by Schwartz [44], with two proxy variables measuring each of the seven universal values of hierarchy, mastery, affective autonomy, intellectual autonomy, egalitarian commitment, harmony, and conservatism.
The Legatum Prosperity Index, first launched in 2007, measures human progress by assessing nine dimensions: Economic Quality, Business Environment, Governance, Personal Freedom, Social Capital, Safety and Security, Education, Health, and the Natural Environment (for a detailed description of the dimensions, see [45, 46]). The HDI and Legatum Prosperity Index are closely related and reliable measures [47], but although they share approximately 75% of their variance, it has been argued that the Legatum Prosperity Index is a more holistic and comprehensive measure than the HDI [45]. Other examples include the Better Life Index [9, 48] and the Social Progress Index (SPI; [49]), which are available for a smaller number of countries.
There are many other models and measures of national well-being (as reviewed, for example, in [50]). Despite notable differences in approaches to the measurement of societal well-being and prosperity, there are also important similarities between different approaches. For example, Phillips [28] provides an integrative review of the societal quality of life models and identifies four common components: civic integration, equal status (e.g., reciprocity, trust, and tolerance), sustainability, and social cohesion.
The purpose of the present study and variable selection
Our interest is in how well a nation is doing in a broad range of domains that reflect various aspects of national prosperity and quality of life. An important limitation of previous studies on societal prosperity and well-being is a lack of attention to the factor structure of the indicators at the societal level, typically including a limited range of dimensions, and focusing on the individual level of analysis. By including a wide range of indicators, both subjective and objective, the present study is expected to provide a more comprehensive evaluation of the structure of prosperity at societal level than previous studies. Our primary aim was to reduce the large array of quality of life variables to a smaller number of derived variables. Thus, we factor analyzed the national indicators to identify the underlying factors or dimensions of societal quality of life.
As previously noted, there is a wide range of views about which dimensions should be included when measuring prosperity. It is clear that not all aspects can be included in a single study, so every approach to selecting the key dimensions has some limitations. Here, we draw extensively upon both personal and societal well-being research but our sole focus is upon the national, rather than the individual level. Thus, we include both objective (such as income inequality and suicide rates) and subjective (such as life satisfaction and eudaimonic well-being) indicators. Our subjective indicators are aggregations of countries’ subjective judgments (as reflected in global surveys). Many of the indicators we include (such as the prosperity indices) are calculated based on both subjective and objective data.
In addition to our commitment to include both subjective and objective measures, we used three other criteria for the selection of component variables. First, given the emphasis on the complementarity of hedonic and eudaimonic aspects, we intended to include indicators of both aspects of well-being. Second, we were committed to including not only positive well-being variables (e.g., life satisfaction, positive affect, and eudaimonic well-being) but also negative mental health variables (i.e., negative affect, depression, anxiety, and suicide). Grinde [51] argues that the mammalian brain has a positive mood as a default setting, so activation of negative feelings is likely to be the main cause of low well-being. Therefore, negative emotions and mental disorders are as important as positive indicators of well-being. Finally, we only included dimensions available in most countries of the world, to maximize the global coverage of the analysis.
Based on these criteria, an initial set of 24 indicators was developed, which are introduced in the methods section and listed in Table 1. Using the data from the Gallup World Poll (GWP), we included the SWB measures of life satisfaction (both present and future), positive affect (emotions: enjoyment, rest, smile/laughter), and negative affect (emotions: stress, sadness, worry, and anger). We also included the newly developed GWP-based measure of eudaimonic well-being [33]. To complement hedonic and eudaimonic well-being indices from the GWP, we also included: (a) eight dimensions of prosperity as measured by Legatum Institute [45, 46]: economic quality, business environment, governance, personal freedom, safety and security, education, health, and natural environment; (b) three proxy measures of mental health: the disability-adjusted life years (DALYs) for depression and anxiety, two frequent mental disorders, and suicide rate; (d) income inequality measured through the Gini Coefficient; (e) globalization measured with the KOF Globalization Index, which assesses three dimensions of globalization: economic, social, and political; (f) friendship opportunities, as an important aspect of social capital and interpersonal relationships.
Tab. 1. Results of exploratory factor analysis (2015–2017, N = 128). We chose the Legatum Prosperity Index over other prosperity models due to its comprehensiveness (covering nine prosperity domains), its inclusion of both subjective and objective data, and its wide geographical (149 countries) and time (since 2007) coverage. However, we excluded the social capital index, given its large overlap with the eudaimonic well-being index. Yet, we included as a separate variable a GWP item used in the social capital index to capture friendship opportunities. We also included measures of income inequality and globalization, which are two other important indicators capturing societies’ functioning [52–54]. It is important to point out that our assortment of variables cover all the important aspects of societal quality of life emphasized in Phillips’s [28] and others’ integrative reviews of the literature. For example, whereas many models of societal prosperity and well-being have ignored environmental sustainability, we measure sustainability via one of the sub-indices of the Legatum Prosperity Index. The natural environment sub-index measures the quality of the natural environment, environmental pressures, and preservation efforts [45, 46].
In addition to examining the structure of prosperity at the national level, the present study also included a number of external variables to establish the nomological networks of the emerging prosperity factors, and examine their discriminant validity. There is ample evidence to suggest that various indicators of well-being have differential associations with other variables. For example, Helliwell, Huang, Wang, and Shiplett [55] found that whereas per-capita income and healthy life expectancy had significant effects only on life satisfaction, freedom and generosity had larger influences on positive affect than on life satisfaction. Diener, Ng, Harter, and Arora [56] found that economic factors (e.g., income, luxury conveniences) were consistently better predictors of life satisfaction than of affective well-being, whereas socio-psychological factors (e.g., fulfillment of psychological needs) were better predictors or affective well-being than life satisfaction. Corruption at the national level has been also found to be more strongly associated with life satisfaction than with positive and negative affect [57]. Therefore, we expected the emerging factors to exhibit differential relationships with external variables. We expected this analysis, not only to establish the discriminant validity of the emerging dimensions, but also to provide additional insights into the nature of these dimensions.
Drawing on prior research, we included a wide range of factors that have been found to affect national well-being, including socio-economic [58], cultural [59], demographic [60] and ecological [61] factors, namely, Hofstede’s dimensions of national culture [62], Inglehart–Welzel cultural dimensions [63], religiosity [64], urbanization [65], national age [66], and indices of thermal climate [67]. In selecting the external variables, we were guided by recent major reviews of the literature [68, 69].
In sum, we aimed at exploring the factor structure of the 24 prosperity and well-being indicators at the societal level and to establish the nomological network of the emerging factors. The general predictions of the present study were: (1) that prosperity will have a multidimensional structure at the national level, and the indicators would form distinct factors, and (2) that different dimensions would show interpretable and differential associations with the external cultural, demographic, and ecological variables.
Methods
Participants
The Gallup World Poll (GWP) dataset between 2015 and 2017 was used to construct the subjective country-level indices. Using randomly selected and nationally representative samples, GWP continually surveys residents in a large number of countries. The final sample of the study consisted of 457,129 individuals in 153 countries for whom data were available on the variables of the study. The average age in the whole sample was 41.72 (SD = 17.77, min = 15, max = 99). Women constituted 53.4% of the sample. The names of the countries, national sample sizes, gender ratios, and average age scores are reported in the supplementary material (S1 Table).
Measures
Variables used in the factor analyses included: life satisfaction (ladder), future life satisfaction, enjoyment, worry, sadness, stress, anger, laughter/smile, eudaimonic well-being, friendship opportunities, rest, economic quality, business environment, governance, personal freedom, safety and security, education, health, natural environment, globalization, depression, anxiety, suicide, and income inequality. It is noteworthy that depression, anxiety, suicide, and income inequality were initially used as indicators in factor analysis, yet based on the initial results we decided to remove them from factor analysis and instead use them as external variables. In a replication analysis, we also included life satisfaction these days, happiness, and purpose in life based on items available in older Gallup data. Variables used as external variables to establish the nomological network of the emerging factors included power distance, uncertainty avoidance, individualism, masculinity, self-expression values, secular-rational values, national age, urbanization, heat demands, and cold demands.
Gallup-based variables included life satisfaction, future life satisfaction, enjoyment, worry, sadness, stress, anger, laughter/smile, friendship opportunities, rest, life satisfaction these days, happiness, purpose in life, and religiosity. All of the GWP variables are based on data collected between 2007–2012 and 2015–2017. We use 2015–2017 data for our main analyses, and 2007–2012 data for replicating the factor analytic findings. The study also included external variables (i.e., variables not from the GWP). All of the external variables refer to the year 2015 (or 2007 for the replication analysis), unless otherwise stated below.
Eudaimonic well-being
This national index [33] was used to measure optimal functioning. The scores are based on the GWP data and refer to the years 2015–2017 and 2007–2012. This index is composed of seven GWP items measuring learning experience, social support, respect, efficacy beliefs, sense of freedom, and pro-sociality (i.e., helping strangers and volunteering).
Other Gallup-based variables
These variables were each measured with a single item. The GWP items used for measuring these variables are shown in S2 Table in the supplementary material. The scores were averaged in each country to construct a national score for that country. Three variables of life satisfaction these days, happiness, and purpose in life were not available in the period 2015–2017, and hence were only used in the analysis based on the 2007–2012 data.
National prosperity
Eight out of nine sub-indices of the Legatum Prosperity Index related to 2007 and 2015 [45, 46] were used to measure various aspects of national prosperity. The nine “pillars” of prosperity include economic quality, business environment, governance, personal freedom, social capital, safety and security, education, health, and natural environment. Each of the sub-indices consists of dozens of objective and subjective variables. More information can be obtained from http://www.prosperity.com. As some of the items used to build the eudaimonic well-being index have also been used in developing the social capital index, social capital was excluded in this study (four out of seven items of the eudaimonic well-being index are shared with the Legatum social capital index, which we consider a large overlap).
It is also noteworthy that the efficacy item used in the eudaimonic well-being index is also used in the business environment subindex of the prosperity index. Some of the affect items (i.e., enjoyment, rest, smile/laughter, and sadness) have been used to construct the health subindex. However, the health subindex consists of a large number of other indicators, and more importantly in the factor analyses, these affect variables and health were found to load on separate factors. Finally, the freedom item which is used in the eudaimonic well-being index is also part of the personal freedom subindex. Again, the personal freedom subindex consists of a large number of other indicators, and eudaimonic well-being and personal freedom loaded on separate factors. Therefore, we decided not to leave out these crucial variables from the analyses to enable a holistic exploration of these important variables.
Globalization
The KOF globalization index [70] related to years 2007 and 2015 was used as a comprehensive measure of globalization, assessing the economic, social, and political dimensions of globalization.
Depression and anxiety
The 2015 data from the Global Burden of Disease Study [71] was used to measure the disability-adjusted life years (DALYs) due to anxiety and depression, including years of life lost from premature death and years lived with less than full health. [One DALY “can be thought of as one lost year of healthy life and the burden of disease as a measurement of the gap between the current health of a population and an ideal situation where everyone in the population lives into old age in full health” [72, p. 1579]. The DALY, is a combinatory metric “designed to quantitatively measure the impact of various diseases and conditions on the productivity and well-being of people through a combination of mortality and morbidity estimates” [73, p. 2].]
Suicide
The 2015 age-standardized suicide rate was used to measure the prevalence of suicide in each country (http://www.who.int/gho/en/).
Income inequality
The GINI estimates for countries were obtained from the UNU-WIDER, World Income Inequality Database (WIID3.4), which is a database of information on income inequality (https://www.wider.unu.edu). All GINI estimates available for each country between the years 2005–2015 were averaged to obtain an income inequality estimate for each nation.
Hofstede’s dimensions of national culture
Hofstede’s four dimensions include power distance (“the degree to which the less powerful members of a society accept and expect that power is distributed unequally”), uncertainty avoidance (“the degree to which the members of a society feel uncomfortable with uncertainty and ambiguity”), individualism (“a preference for a loosely-knit social framework in which individuals are expected to take care of only themselves and their immediate families”), and masculinity (“a preference in society for achievement, heroism, assertiveness, and material rewards for success”) [74]. The scores for each country were obtained from Hofstede, Hofstede, and Minkov [75].
Inglehart—Welzel cultural dimensions
Scores of self-expression/survival values (the extent to which people prioritize individual choice over survival needs) and traditional/secular-rational values (the extent to which people emphasize modern values over traditional values such as religion, absolute standards, and conventional family values) were based on the data from the World Values Survey, Wave 6 (2011–2014). For countries that did not participate in Wave 6, data from Wave 5 (2005–2008) was used [76].
National age
In order to measure national age, percentages of the population that are aged 65 and above in each country were used. The data were obtained from https://data.worldbank.org.
Religiosity
We used Joshanloo and Gebauer’s [77] Gallup-based index of religiosity. This index is calculated as the percentage of people per country who stated that religiosity is an important part of their daily lives.
Urbanization
In order to measure the national degree of urbanization, percentages of the urban population in each country in the year 2018 were used. The data were obtained from the world urbanization prospects at https://esa.un.org/unpd/wup/.
Temperature
Van de Vliert’s [78] indices of thermal climate were used to measure temperature. The hot and cold measures are based on winter and summer deviations from a biologically optimal point of reference (i.e., 22°C or about 72°F). Climatic demands “are operationalized across each country’s or region’s major cities, weighted for population size, as the sum of the absolute deviations from 22°C for the average lowest and highest temperatures in the coldest month and in the hottest month” [78, p. 470].
Results
The analyses started with the main dataset related to 2015–2017. A principal axis factoring with promax rotation (Kappa = 2) was run using the 24 variables (the correlation matrix for the 24 variables is shown in S3 Table in an excel file). Only 128 countries with complete data were included. Scree plot suggested a 3-factor solution. The factor loadings of this initial model are shown in Table 1. Four variables demonstrated unexpected loadings. Anxiety and depression had positive loadings on the first factor. Income inequality had a positive loading on the second factor. Finally, suicide did not have a substantial loading on any of the factors. We decided to omit these four variables from the factor analysis and instead use them as external variables. This decision was driven by the fact that our aim was to identify unambiguous interpretable factors. In addition, these results cast doubt on the suitability of these variables to measure societal well-being (as further discussed in the discussion section). Thus, to maintain more intuitive factors, these four variables were removed from the analysis and factor analysis was repeated with 138 countries that had complete data on the remaining 20 variables.
Again the Scree test suggested a three-factor solution. The results are shown in Table 2. The three factors collectively explained about 68.02% of the variances in the variables. The first factor is loaded by globalization, and all aspects of national prosperity as well as life satisfaction (i.e., the ladder question). Generally speaking, this factor represents globalization and modern (vs traditional) values, as well as financial and socio-political development, and hence can be labeled as “Socio-Economic Progress”.
Tab. 2. Results of exploratory factor analysis (2015–2017, N = 138). The second factor is dominated by psychological and subjective variables, including eudaimonic well-being and positive affective states. With variables such as smile/laughter, eudaimonic well-being, future life satisfaction, enjoyment, and friendship opportunities, this factor measures a vital and psychosocially rich lifestyle. Thus, this factor can be labeled as “Psycho-Social Functioning”. Finally, the last factor is comprised of subjective feelings of worry, sadness, stress, and anger, and thus the factor can be labeled as “Negative Affectivity”. Higher scores on the last factor would mean higher levels of Negative Affectivity.
Replication of factor structure in data from 2007–2012
The same variables were constructed from GWP data collected between 2007 and 2012. The prosperity and globalization variables were related to 2007. As can be seen in Table 3, the emerging factor structure was largely similar to the results with more recent data. The same factors emerged. The 2007–2012 data included three extra variables for a smaller number of countries: happiness, life satisfaction these days, and purpose in life. These three variables were included in a separate factor analysis with a smaller sample size (N = 88). As shown in Table 4, the same factor structure was replicated. Life satisfaction these days loaded onto Socio-Economic Progress, and happiness and purpose in life loaded on Psycho-Social Functioning.
Tab. 3. Results of exploratory factor analysis (2007–2012, N = 141). Tab. 4. Results of exploratory factor analysis (2007–2012, N = 88). Factor correlations and country rankings
The consecutive analyses are entirely based on 2015–2017 data. The 20 variables (used in Table 2) were all z-standardized (to give a fairly equal presence to each variable in the final composite variables) and averaged to form three higher-level variables of Socio-Economic Progress, Psycho-Social Functioning, and Negative Affectivity. The Socio-Economic Progress score was calculated for nations with a single missing value as well. As shown in Table 5, observed correlations are stronger than latent correlations. In general, however, the correlations are modest, suggesting that a country’s standing on one of the dimensions does not strongly predict its standing on other dimensions. S1, S2 and S3 Figs in the supplementary material show the pairwise relationships between the variables. A three-dimensional scatterplot is shown in Fig 1. Cronbach’s alphas for each of the three variables based on the standardized variables are reported in Table 5, indicating acceptable internal consistency for each of the variables. Table 6 presents national scores and rankings.
Tab. 5. Factor correlations and alphas. Tab. 6. Country scores. Fig. 1. Three-dimensional scatterplot. Regional distribution of national prosperity and well-being
Fig 2 shows the regional levels of the three prosperity variables. The names of countries in each category are shown in S4 Table. In terms of Socio-Economic Progress, Northern America, Australia, and New Zealand have the highest scores, whereas Sub-Saharan Africa and South Asia have the lowest scores. On Psycho-Social Functioning, Northern America, Australia, and New Zealand have the highest scores; Commonwealth of Independent States and Middle East and North Africa have the lowest scores. Finally, on Negative Affectivity, Middle East and North Africa have the highest score, whereas Commonwealth of Independent States, Australia, and New Zealand and East Asia have the lowest scores. Note that a high score on Negative Affectivity is not a ‘good’ score–high levels of negative affect are undesirable. The top-ranked countries here are Iraq and Syria, both blighted by civil war in recent years.
Fig. 2. Regional averages. The nomological network of the three dimensions
Table 7 presents the correlations between the three prosperity variables and the external variables of the study. The correlations with the four variables removed from the factor analysis are also presented in the table. As can be seen, most of the variables have differential associations with the external variables. This suggests that the variables have partly unique nomological networks.
Tab. 7. Correlations between the well-being dimensions and external variables. Discussion
Based on the results of the factor analysis, we identified three interpretable factors suggesting that, within the complex picture presented by the wide range of available indicators, distinct concepts are discernible. Below, we elaborate on the nature of the three factors.
Factor 1: Socio-Economic progress
This factor is loaded by variables that mostly reflect external conditions of life (as opposed to subjective and psychological feelings), country-level situations, and the functioning of public, social, and political institutions. Globalization and all of the prosperity sub-indices loaded on this factor. The indicators of this factor are partially based on people’s opinions as expressed in large-scale surveys, with survey questions mostly capturing people’s opinions about the socio-economic situations around them. The variables loading on this factor are primarily dependent on economic growth. Surprisingly, life satisfaction (ladder of life) too loaded on this factor, as its only purely subjective indicator. Cantril’s ladder of life has been shown to be more closely associated with socio-economic indicators than standard single-item life satisfaction measures (e.g., All things considered, how satisfied are you with your life as a whole these days?) [50]. However, in our supplementary analysis, we found that satisfaction these days also loaded on Factor 1 (Table 4). Unlike other subjective indices (such as affect and eudaimonic well-being), national life satisfaction does not seem to reflect well how life is subjectively experienced on a day-to-day basis. Instead, it seems largely to reflect how people perceive, or are affected by, economic and socio-political developments in their nations. This finding is consistent with evidence that economic, political, and social stress at the national level (e.g., crisis and war) can lead to rather rapid declines in a nation’s level of life satisfaction [40, 79, 80].
Life satisfaction can be seen as an indicator of the extent to which people are getting what they want in life. Our results suggest that, when people’s satisfaction responses are aggregated to calculate national scores of satisfaction, they align well with countries’ objective levels of development. Previous research has also found strong correlations (e.g., > .7) between national life satisfaction and economic and prosperity indicators [33, 40, 81]. Thus, it can be surmised that life satisfaction questions (particularly ladder of life) encourage people to think of their lives in economic terms [82]. This raises the question whether the overlap between country-level life satisfaction and Socio-Economic Progress is sufficient to create redundancy such that the simultaneous use of socio-economic indicators and life satisfaction at the country level adds little benefit, or worse, causes issues of multicollinearity (e.g., when using these indicators simultaneously as predictors in regression models). This large overlap also suggests that the availability of reliable measures of socio-economic development for a country may reduce the need for relying on life satisfaction measures, if the outcome variable of interest is Socio-Economic Progress. Conversely, however, given its strong loading on the first factor, national life satisfaction could be considered as a valid and highly useful summary index of general socio-economic development in large groups (e.g., nations). This is particularly so at the community or group level (e.g., with ethnic and cultural groups within nations, socio-economic classes, and neighborhoods), where reliable group-level indicators may be nonexistent.
Factor 2: Psycho-Social functioning
This factor is more subjective than Factor 1, being loaded by positively-valenced mental states (smile/laughter, future life satisfaction, well-rested, and enjoyment) as well as eudaimonic well-being and friendship opportunities. In the additional analysis, we found that happiness (close to enjoyment) and purpose in life (close to eudaimonic well-being) also loaded on this factor. These variables have in common an emphasis on inner feelings, psychological and interpersonal resources and functioning in life rather than external living conditions. This factor also covers social domains of well-being including altruism and social capital. In sum, this factor reflects a version of well-being that emphasizes living a worthwhile, hopeful, and enjoyable life involving pleasant states of mind but also developing and exercising personal and social skills.
Our finding that life satisfaction loaded on Factor 1 but affective variables loaded on other factors resonates with previous research concerning differential results for life satisfaction and positive affect. Earlier studies have found that national happiness is not correlated with life-satisfaction [83], and that affective measures are more sensitive to circumstances that evoke positive and negative emotions and less so to socioeconomic status, economic conditions, income, and material variables [84–87]. The fact that life satisfaction measures loaded on Factor 1 and happiness loaded on Factor 2 suggests that different conclusions can be drawn using different SWB measures, and that findings produced by one measure might not hold for other measures. Thus great caution is needed when comparing the results of studies using different measures of well-being [88].
An important finding is that the present and future life satisfaction loaded on different factors. Gallagher, Lopez, and Pressman [89] argue that future life satisfaction measures the expectation of positive future outcomes and thus is a face-valid measure of optimistic expectations for the future. At the individual level, future life satisfaction has been found to have a stronger correlation with optimism and hope than do present and past satisfaction [90, 91]. The present country-level results are in keeping with the previous results. Our results show that, compared with present life satisfaction, future life satisfaction is associated less strongly with current socio-economic conditions and more strongly with positive affect and eudaimonic well-being. These results suggest that, at the country level, future life satisfaction is more likely to measure positive emotions and attitudes such as hope and optimism than evaluations of objective living conditions. Given the dearth of country-level studies involving future life satisfaction, these explanations and suggestions need to be further investigated in future studies. Yet, our findings do clearly indicate that future and present life satisfaction are distinguishable in interpretable ways, which needs to be acknowledged in future research.
We found that eudaimonic well-being also did not load on socio-economic prosperity. This too is consistent with previous research [33, 92]. The present results and previous research [93] leads us to predict that eudaimonic well-being is less likely than life satisfaction to change rapidly in response to economic and political stress at the national level, a prediction to be tested empirically in future research.
Factor 3: Negative affectivity
Of the three, Factor 3 is the most homogeneous: sadness, worry, stress, and anger, are all negatively-valenced affective states, and can be broadly categorized as forms of displeasure. Hence, this factor captures individuals’ day-to-day experience of unpleasant affect, and thus can be considered a measure of ill-being. However, it can be transformed into a positive well-being measure if reverse-scored. Whereas the separation of Factor 1 from the other two factors is interpretable in view of the level of subjectivity of the indicators concerned, the distinction between Factors 2 and 3 is not based on the levels of subjectivity but on the valence of the subjective states. This distinction is consistent with the predominant view that positive and negative affect are largely independent of each other, rather than two sides of the same coin [94]. Grinde [51] argues that this distinction is particularly important in that positive and negative affect have differential associations with one’s overall level of functioning.
Helliwell et al. [55] showed that positive emotions were more strongly associated with life satisfaction than were negative emotions and that positive and negative affect had differential relationships with other variables (e.g. generosity and perceptions of corruption). Our results indicate that, at the country level, positive affect is more strongly associated with eudaimonic well-being, future satisfaction, happiness, friendship opportunities, and feeling well-rested than is negative affect. Our results converge with the previous results in suggesting that positive and negative affect capture two different aspects of country-level well-being and should be studied independently.
Nomological networks
The three factors showed clearly distinct nomological networks. Below, we highlight some of the findings related to each of the factors.
Factor 1: Socio-Economic progress
This dimension was correlated with all of the external variables, except suicide and uncertainty avoidance. The strongest correlations were with national age (i.e., % aged over 65), religiosity (negative), self-expressive values, and individualism. This pattern is consistent with the general expectations of socio-economic development. For example, developed countries tend to have older populations, and endorse more secular and individualistic values [95]. The factor has a positive correlation with cold demands and a negative association with heat demands. It is also correlated with anxiety and depression. People in richer countries are less likely to report that their lives have a meaning [92], which may contribute to higher levels of depression. Research has also found that richer countries are also more likely to have a higher prevalence of some health problems such as obesity, and alcohol use [96–98]. Therefore, a high level of Socio-Economic Progress is not a panacea, and these countries still have challenges to face. It is not clear whether these challenges are products of higher Socio-Economic Progress or remnants of pre-existing problems that Socio-Economic Progress has not yet been able to solve; or whether rising levels of Socio-Economic Progress will resolve these issues, intensify them, or leave them unaffected.
Factor 2: Psycho-Social functioning
This factor had relatively weaker correlations with the external variables than the other two factors, which reflects its strongly subjective content. It has its strongest correlation with self-expressive values, other correlations being nonsignificant, weak, or moderate. Unlike the other two factors, it had no association with temperature. This pattern of associations suggests that societies with higher levels of Psycho-Social Functioning are more likely to emphasize subjective quality of life and self-expression over economic and physical security [95], and are open to situations that are novel, unknown, and different from usual [75]. We speculate that Psycho-Social Functioning’s orthogonality to suicide as reflected in the multidimensional plots is largely a result of its association with meaning in life. A strong endorsement of self-expressive values is one of the main commonalities between countries that are high both on Socio-Economic Progress and Psycho-Social Functioning. Finally, Psycho-Social Functioning has a weak but significant positive correlation with anxiety.
Psycho-Social Functioning’s weaker associations with secular/individualistic values as well as economic and political situations suggests that developing countries are more likely to score well on this type of well-being than on Socio-Economic Progress. This is reflected in the fact that some African countries which suffer from life dissatisfaction have better standings on eudaimonic well-being (e.g., Mali, Libya, Nigeria).
Factor 3: Negative affectivity
This variable has weaker associations with the external variables than Socio-Economic Progress. Its strongest correlation is with secular values (negative), religiosity (positive), and cold demands (negative). The pattern of correlations for this variable suggests that negative affect is higher in more collectivistic, hotter, less urbanized countries, countries with younger populations and higher levels of uncertainty avoidance, power distance, and income inequality. This suggests that negative affect is inversely associated with socio-economic development and the endorsement of progressive values.
Dimensionality of national quality of life
Our data-driven exploratory analysis provides a plausible framework for understanding and appraising quality of life at societal level, and supports the view that country-level quality of life is a multidimensional construct, not a holistic entity that can be measured adequately by a single measure. Our two-dimensional plots of variables do not provide evidence of centrality for any of the variables. Our results are consistent with Diener and Suh’s [13] conclusion that objective, and subjective indicators are complementary, each capturing different aspects of societal well-being, and thus should be used in parallel. Therefore, it is necessary for future research to study the three dimensions separately as well as in tandem.
Quality of life of a given country differs substantially depending on the measure used to operationalize it. For example, the use of objective measures of material wealth may produce different rankings from measures of social and psychological resources [56, 99]. Similar findings were observed in the present study. All the countries that ranked in the top ten on the Socio-Economic Progress dimension (Switzerland, Finland, Norway, New Zealand, Sweden, the Netherlands, Denmark, Canada, Germany, Australia) are affluent countries from Nordic, Anglo, and Western-European societies. On the other hand, the top 10 countries in the psychosocial functioning dimension are more diverse (Uzbekistan, Indonesia, Norway, United Arab Emirates, Denmark, Canada, the Netherlands, New Zealand, Costa Rica, Ireland), as are the 10 countries that rank lowest in Negative Affectivity (Uzbekistan, Taiwan, Russia, Kazakhstan, Somalia, Kyrgyzstan, Mongolia, Azerbaijan, Singapore, Belarus).
Our regional analysis also shows the importance of considering the dimensions separately. Whilst the pattern of high and low scores across different regions was broadly similar between Socio-Economic Progress and Psycho-Social Functioning, South and Southeast Asia, Latin America and Sub-Saharan Africa scored higher on the latter than the former, whereas the reverse was true of European, Commonwealth of Independent States and Middle Eastern countries. Comparing Negative Affectivity with the other two factors revealed some more marked differences. Commonwealth of Independent States and East Asian countries had much better scores on this factor than the other two (a low score on Negative Affect being a good score); Northern America rather worse. These differences underline the complexity of prosperity and well-being at the national level. The fact that certain countries scored better or worse on Socio-Economic Progress than the other factors suggests that the aspects of prosperity which make up this factor do not tell the whole story of what influences well-being at the national level. Some countries, such as Nigeria and Paraguay, scored markedly better on Factors 2 and 3 than Factor 1 (Table 6). Therefore, a nation’s standing on one dimension may not accurately reveal its standing on the others. These findings militate against a reductive and simplistic approach that assumes a single gold standard measure of quality of life. Our results unmistakably indicate that using a single measure of national prosperity is inappropriate and may lead to simplistic conclusions.
Although positive and negative affect along with life satisfaction tend to form a SWB factor in studies on individual-level indicators of well-being (for a review, see [39]), in our national level analysis, these variables loaded on three distinct factors. Thus, conclusions about the structure of well-being obtained at the individual level should not be automatically translated to assumptions about the structure of prosperity and well-being at the national level.
An interesting finding was that Socio-Economic Progress and Psycho-Social Functioning had a stronger correlation than Psycho-Social Functioning and Negative Affectivity (Table 5). In general, the Negative Affectivity factor is more distinct from the other two factors. This finding is difficult to explain given that negative affect has been rarely studied at national level and not much is known about it. Yet, the finding is consistent with Helliwell et al.’s [55] findings suggesting that negative affect is less fully explained by other well-being and prosperity variables than are life satisfaction and positive affect, and is less strongly associated with life satisfaction than positive affect is. In sum, these results are suggestive of both complementarity of and overlap between the three dimensions.
Anxiety, depression, suicide, and income inequality
The four variables of anxiety, depression, suicide, and income inequality are considered by some as important components of country-level quality of life [28, 52]. For anxiety, depression, and suicide, these assumptions seem to be largely based on individual-level findings. For example, a depressed and anxious person is almost certainly not very happy. Yet, we found that, at the national level, these variables do not connect with the other indicators in an expected manner, which may cast doubt on their utility in measuring national quality of life (i.e., quality of life in the whole national population).
Depression had a positive loading on Factor 1, and its loading on Factor 3 was almost zero. Yet, it had a weak negative loading on Factor 2, which is consistent with the general expectations, since this factor involves variables such as meaning in life and positive affect that are antithetical to depression. Anxiety also had an expectedly positive loading on the first factor, and a loading in the expected direction but weaker on Factor 3. Given these mixed results, it is doubtful that depression and anxiety can be used as unambiguous indicators of national quality of life. Instead, we suggest using depression and anxiety as indicators of quality in life in depressed and anxious populations in a given country, as vulnerable populations that deserve special care. It is worth noting that we used the DALYs due to anxiety and depression (produced by the global burden of disease study), which are incidence-based measures that combine both mortality and morbidity into a single value [73]. Alternative national measures of anxiety and depression (e.g., prevalence-based measures) may lead to different conclusions.
Surprisingly, suicide had a weak but nontrivial negative loading on Factor 3, and trivial loadings on the other factors. Some previous studies have also found positive correlations between suicide rates and SWB [100, 101]. The suicide rate has been excluded from the most recent update of the Social Progress Index due to low correlations with other indicators of health and wellness [102]. Daly et al. [100] suggest that personal unhappiness may be at its worst when surrounded by those who are relatively more content with their lives. Diener and Suh [13] suggest that in high-SWB and high-income countries, there may be less social support and security when life goes badly as well as higher chances of loneliness which may lead to higher rates of suicide. In other words, higher levels of freedom in these countries have both the desirable effect of increasing SWB and the undesirable effect of increasing the possibility of suicide for people whose lives go badly. Based on these findings, national suicide rates cannot be used as an unambiguous nation-level quality of life indicator, and instead could be used for monitoring the status of people with suicidal tendencies and other affected populations in any given country.
Income inequality has shown positive, negative, and ambiguous associations with SWB [40, 103]. There is evidence that inequality may increase well-being in some nations but not others [104–106]. Similarly, inequality’s association with economic growth is also not clear-cut [107]. We also found mixed results for income inequality. It had a negative loading on the first factor, and surprisingly a positive loading on the second factor. Therefore, our results dovetail with the previous evidence in suggesting that income inequality is not an unambiguous indicator of national quality of life. Therefore, we suggest not including income inequality as an indicator of country-level quality of life. Instead, income inequality could be studied in its own right as an important nation-level variable that can have complex and heterogeneous relationships with various aspect of national quality of life in various contexts and groups.
In view of the mixed pattern of associations with the other indicators, we excluded these variables from our factor analysis and instead used them as external variables to establish the nomological networks of the quality of life variables. We acknowledge that theory-driven treatments of national quality of life may be more open to including these four variables as component parts, yet, our data-driven approach hinders this on the grounds of the ambiguous factor analytic and correlational findings for these variables.
Relevance to public policy
This paper was intended to investigate holistically the structure of prosperity and well-being at the national level rather than to directly inform public policy. Nevertheless, we do believe that our findings would be of interest to policy makers. For example, the fact that our results support a broadly-based approach to measuring well-being, involving a mix of subjective and objective measures and avoiding over-reliance on any single type of measure is relevant to national well-being programmes as well as to academic research. In addition, the performance of nations varies across the three factors, so that a nation’s standing on one dimension does not reveal its standing on the others. This clearly cautions against over-reliance on unidimensional means of improving well-being–for example, an exclusive focus on economic prosperity. Thus, our results provide a comprehensive and multidimensional picture of well-being to inform the development of public policy. We hope that future studies will build on our work to provide results of more direct relevance to specific policy issues. For example, future studies might consider factor-analysis on sub-categories of measures organized by different policy objectives rather than across the full range.
Limitations and future research
Some of the limitations of this study need to be mentioned. First, the choice of indicators affects the results of factor analysis. The obtained factor structure in any factor analysis is inevitably contingent on the selected variables. Our selection of variables of national well-being is of course not definitive. Other subjective and objective indicators of national well-being could be incorporated in future studies on the structure of human well-being at the national level, to see if conclusions are affected in significant ways. As new scientific methods and data sources for measuring well-being at the nation level are emerging (for example, the use of language or text data to infer national well-being [108]), future studies can include more measures of well-being from diverse sources. Second, the GWP has its limitations, e.g., the single-item measures used to assess most of the concepts. Future research will need to use more reliable measures. Subjective measures of quality of life have been criticized on various grounds, including equivalence in translation and psychometrics [109, 110]. For example, researchers have emphasized that to make meaningful cross-cultural comparisons, equivalence and bias need to be addressed in cross-cultural surveys [111, 112]. More research in this area is needed to examine the magnitude of the effect of these artifacts on the measurement of well-being across cultures. Third, we used a limited number of external variables to validate the structure of national well-being that emerged in the present study. Future studies could include additional predictors or outcomes of well-being such as progressive taxation, personality traits, and crime rates (for a review, see [58]). Fourth, given the cross-sectional nature of our data, causality may not be inferred and future research needs to use longitudinal research designs to shed light on the direction of causality.
Finally, cross-national comparisons and ranking of countries are subject to a variety of caveats, which deserve special attention. The ranking of nations against the three factors: Factor 3 in particular–produced some surprising results. For example, whilst Iraq and Syria, which have endured bloody internal conflict, had the highest levels of negative affect, Somalia, a country experiencing similar strife, had one of the lowest. The predominance of former Soviet countries among those reporting the lowest levels of negative affect is also difficult to explain. We acknowledge that these–and perhaps other–results may have been influenced by other factors affecting the responses (e.g., for example, cultural factors or response sets) as well as by actual levels of negative affect. As argued by Tov and Au [113] cross-national differences in well-being and country ranking on well-being variables need to be interpreted with caution. The equivalence of meaning of SWB concepts (e.g., life satisfaction and happiness) should be carefully inspected in studies aimed at comparing countries on well-being measures, because these terms might mean different things to individuals from different cultures. For example, previous studies have found that meanings of, and attitudes to, terms such as “happiness” and “life satisfaction” may vary across languages and cultures [110, 114–116]. Therefore, a necessary avenue for future research would be to tease out cultural influences systematically.
Concluding remarks
The limitations of GDP and similar wealth indicators have led to the development of numerous ideas and frameworks to measure national quality of life and provide information relevant to public policy. SWB, particularly its cognitive component (i.e., life satisfaction) has received extensive attention in this area of research and practice. Our results expanded these insights in various ways. For example, we found that, in comparison to life satisfaction, the affective components of SWB reflect information that is more likely to be different from that already captured by economic indicators. Moreover, our results on the structure of prosperity and well-being variables provide a systematic way to look at the diverse indicators and their interrelations. For example, the results suggest that eudaimonic well-being has stronger associations with positive affect than life satisfaction and Socio-Economic Progress, and eudaimonic well-being is also more likely than life satisfaction to provide information that is different from economic indicators. Our results also call into question the practice of categorizing affect and life satisfaction under the title of “subjective well-being” at the country level. This conceptualization stems from individual-level results and we showed in this article that it was not consistent with country-level results.
Delle Fave [30] highlights the current need for a more integrated and articulated perspective in the selection, use and interpretation of well-being indicators. One way to make progress towards satisfying this pressing need is data-driven explorations of the factor structure of the societal indicators of quality of life. Our study seems to be the first broad and inclusive study of this sort, aimed at organizing a large list of indicators in a conceptual structure. Inquiry into the structure of well-being at the national level is of crucial importance at this stage of development in this field of research. The results of such studies can help us avoid over-reductionism, and instead enable a systematic identification of elementary indictors to efficiently reduce the number of variables. Such studies help to balance the hegemony of particular approaches over others [117]. They can also support the development of empirically-informed conceptual frameworks. It is, however, appropriate to be cautious at this stage, in view of the fact that this study is among the first factor-analytic studies of prosperity and well-being at the country level. Thus, our findings should be considered preliminary. It is hoped that these results will stimulate more research endeavors aimed at clarifying the structure of national prosperity and well-being. It is noteworthy that studies of this nature involve ecological analyses the results of which do not necessarily have implications for individuals [83].
In conclusion, the results of our research paint a complex and promising–if provisional–picture of prosperity and well-being at the national level. The complexity of the relationships between the three well-being factors, and between them and other variables, underlines the need for a broadly-based approach to the measurement of well-being, avoiding over-reliance on any single indicator such as life satisfaction. We hope that other researchers will carry out further work to expand and advance these findings.
Supporting information
S1 Fig [docx]
The relationship between psycho-social functioning and socio-economic progress.S2 Fig [docx]
The relationship between negative affectivity and socio-economic progress.S3 Fig [docx]
The relationship between negative affectivity and psycho-social functioning.S1 Table [docx]
Descriptive information for the main dataset (2015–2017).S2 Table [docx]
Gallup items used in the study.S3 Table [xlsx]
Intercorrelations between the 24 indicators.S4 Table [docx]
Global regions (Gallup’s categorization).
Zdroje
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- The Ps and Qs of alarmone synthesis in Staphylococcus aureus
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- Assessing introgressive hybridization in roan antelope (Hippotragus equinus): Lessons from South Africa
- Robust sound event detection in bioacoustic sensor networks
- DNA methylation, microRNA expression profiles and their relationships with transcriptome in grass-fed and grain-fed Angus cattle rumen tissue
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- Host-feeding patterns of Aedes (Aedimorphus) vexans arabiensis, a Rift Valley Fever virus vector in the Ferlo pastoral ecosystem of Senegal
- The inhibitory effects of butein on cell proliferation and TNF-α-induced CCL2 release in racially different triple negative breast cancer cells
- The long-run effects of secondary school track assignment
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- Measuring the impact of an interdisciplinary learning project on nursing, architecture and landscape design students’ empathy
- Characterising the harmonic vocal repertoire of the Indian wolf (Canis lupus pallipes)
- Childhood conditions, pathways to entertainment work and current practices of female entertainment workers in Cambodia: Baseline findings from the Mobile Link trial
- Adoption and consequences of new light-fishing technology (LEDs) on Lake Tanganyika, East Africa
- An innovative non-invasive technique for subcutaneous tumour measurements
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- Comparison of long-term outcomes between enteral nutrition via gastrostomy and total parenteral nutrition in older persons with dysphagia: A propensity-matched cohort study
- Kinetic characteristics of propofol-induced inhibition of electron-transfer chain and fatty acid oxidation in human and rodent skeletal and cardiac muscles
- Simple methods to obtain food listing and portion size distribution estimates for use in semi-quantitative dietary assessment methods
- Cardiorespiratory factors related to the increase in oxygen consumption during exercise in individuals with stroke
- A multi-level society comprised of one-male and multi-male core units in an African colobine (Colobus angolensis ruwenzorii)
- Development of rice conidiation media for Ustilaginoidea virens
- Variation in Neotropical river otter (Lontra longicaudis) diet: Effects of an invasive prey species
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- Algorithmic differentiation improves the computational efficiency of OpenSim-based trajectory optimization of human movement
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- Analysis of drug-induced hearing loss by using a spontaneous reporting system database
- Spectral measure of color variation of black-orange-black (BOB) pattern in small parasitoid wasps (Hymenoptera: Scelionidae), a statistical approach
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- A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy
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- Transcriptome analysis of Xanthomonas oryzae pv. oryzicola exposed to H2O2 reveals horizontal gene transfer contributes to its oxidative stress response
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- Development and multi-cohort validation of a clinical score for predicting type 2 diabetes mellitus
- Chronic stability of single-channel neurophysiological correlates of gross and fine reaching movements in the rat
- Neural, functional, and aesthetic impacts of spatially heterogeneous flicker: A potential role of natural flicker
- Clinical and laboratorial profiles of dengue virus infection in kidney transplant recipients: Report of a single center
- Bioaccumulation of heavy metals in some commercially important fishes from a tropical river estuary suggests higher potential health risk in children than adults
- Factors associated with unsuppressed viremia in women living with HIV on lifelong ART in the multi-country US-PEPFAR PROMOTE study: A cross-sectional analysis
- Comparing low-cost handheld autorefractors: A practical approach to measuring refraction in low-resource settings
- Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth
- Computational screening of antimicrobial peptides for Acinetobacter baumannii
- Isolation of secreted proteins from Drosophila ovaries and embryos through in vivo BirA-mediated biotinylation
- Differentiating electrophysiological indices of internal and external performance monitoring: Relationship with perfectionism and locus of control
- The N125S polymorphism in the cathepsin G gene (rs45567233) is associated with susceptibility to osteomyelitis in a Spanish population
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- Monitoring and characterizing soluble and membrane-bound ectonucleotidases CD73 and CD39
- Trace amine-associated receptor gene polymorphism increases drug craving in individuals with methamphetamine dependence
- Bayesian inverse methods for spatiotemporal characterization of gastric electrical activity from cutaneous multi-electrode recordings
- Tracheostomy and long-term mortality in ICU patients undergoing prolonged mechanical ventilation
- Evolutionary history and classification of Micropia retroelements in Drosophilidae species
- Low-glutathione mutants are impaired in growth but do not show an increased sensitivity to moderate water deficit
- Exploring the basis of 2-propenyl and 3-butenyl glucosinolate synthesis by QTL mapping and RNA-sequencing in Brassica juncea
- Trends in the use of antimuscarinics and alpha-adrenergic blockers in women with lower urinary tract symptoms in Taiwan: A nationwide, population-based study, 2007-2012
- Can knowledge of election results change recall of our predictions? Neural correlates of political hindsight bias
- Risk factor profiles and clinical outcomes for children and adults with pneumococcal infections in Singapore: A need to expand vaccination policy?
- Multilevel legal approaches to obesity prevention: A conceptual and methodological toolkit
- Prevalence, associated factors and health impact of intimate partner violence against women in different life stages
- The effect of yoga practice on glycemic control and other health parameters in the prediabetic state: A systematic review and meta-analysis
- Decreased breast cancer-specific mortality risk in patients with a history of thyroid cancer
- Intestinal parasitic infection among household contacts of primary cases, a comparative cross-sectional study
- An automatic approach for classification and categorisation of lip morphological traits
- Time series analysis and forecasting with ECOTOOL
- OCT-Angiography: Mydriatic phenylephrine and tropicamide do not influence retinal microvasculature in macula and peripapillary region
- Azithromycin non-susceptible Shigella circulating in Israel, 2014–2016
- The effectiveness of a community-based, type 2 diabetes prevention programme on health-related quality of life. The DE-PLAN study
- Predictors, causes, and trends of neonatal mortality at Nekemte Referral Hospital, east Wollega Zone, western Ethiopia (2010–2014). Retrospective cohort study
- Management factors affecting adrenal glucocorticoid activity of tourist camp elephants in Thailand and implications for elephant welfare
- Brain metastasis-related microRNAs in patients with advanced breast cancer
- Soil erosion and corn yield in a cultivated catchment of the Chinese Mollisol region
- A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression
- Empathy affects tradeoffs between life's quality and duration
- Novel approaches to model effects of subconjunctival blebs on flow pressure to improve clinical grading systems after glaucoma drainage surgery
- Validation of a simple extraction procedure for bisphenol A identification from human plasma
- Global incidence of prostate cancer in developing and developed countries with changing age structures
- Variation in bone response to the placement of percutaneous osseointegrated endoprostheses: A 24-month follow-up in sheep
- Preventable pediatric hospitalizations and access to primary health care in Italy
- Anemia and its associated factors among adult people living with human immunodeficiency virus at Wolaita Sodo University teaching referral hospital
- A system for bedside assistance that integrates a robotic bed and a mobile manipulator
- A global sampler of single particle tracking solutions for single molecule microscopy
- Homotopic region connectivity during concussion recovery: A longitudinal fMRI study
- Decrements of body mass index are associated with poor outcomes of idiopathic pulmonary fibrosis patients
- The effectiveness of the quality improvement collaborative strategy in low- and middle-income countries: A systematic review and meta-analysis
- An intrusion detection algorithm for sensor network based on normalized cut spectral clustering
- Pregnane X receptor activation constrains mucosal NF-κB activity in active inflammatory bowel disease
- Do minimum wage laws affect those who are not covered? Evidence from agricultural and non-agricultural workers
- Multi-breed genome-wide association studies across countries for electronically recorded behavior traits in local dual-purpose cows
- Sensitivity to changes in dynamic affordances for walking on land and at sea
- Dombi power partitioned Heronian mean operators of q-rung orthopair fuzzy numbers for multiple attribute group decision making
- Correction: Feed Conversion, Survival and Development, and Composition of Four Insect Species on Diets Composed of Food By-Products
- Impact of visual impairment on physical activity in early and late age-related macular degeneration
- A fuzzy logic decision support model for climate-driven biomass loss risk in western Oregon and Washington
- Skeletal development in the sea urchin relies upon protein families that contain intrinsic disorder, aggregation-prone, and conserved globular interactive domains
- Investigating the potential of the secretome of mesenchymal stem cells derived from sickle cell disease patients
- Cardiac output measurements via echocardiography versus thermodilution: A systematic review and meta-analysis
- Quantitative assessment of plant-arthropod interactions in forest canopies: A plot-based approach
- Genetic modification and yield risk: A stochastic dominance analysis of corn in the USA
- Cryptic diversity of limestone karst inhabiting land snails (Cyclophorus spp.) in northern Vietnam, their evolutionary history and the description of four new species
- Impact of group antenatal care (G-ANC) versus individual antenatal care (ANC) on quality of care, ANC attendance and facility-based delivery: A pragmatic cluster-randomized controlled trial in Kenya and Nigeria
- The relationship between management practices and the efficiency and quality of voluntary medical male circumcision services in four African countries
- Using AST-platelet ratio index and fibrosis 4 index for detecting chronic hepatitis C in a large-scale community screening
- Incidence and predictors of retreatment in chronic hepatitis B patients after discontinuation of entecavir or tenofovir treatment
- Elderly HIV-positive women: A gender-based analysis from the Multicenter Italian “GEPPO” Cohort
- Attitudes and perceptions towards hypoglycaemia in patients with diabetes mellitus: A multinational cross-sectional study
- Plasma mitochondrial DNA is elevated in obese type 2 diabetes mellitus patients and correlates positively with insulin resistance
- [Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti–CTLA-4 antibody in a mouse model
- A global spatial analysis reveals where marine aquaculture can benefit nature and people
- Association between mitochondrial genetic variation and breast cancer risk: The Multiethnic Cohort
- Incorporating evaporative water loss into bioenergetic models of hibernation to test for relative influence of host and pathogen traits on white-nose syndrome
- Feasibility and effectiveness of electronic vs. paper partograph on improving birth outcomes: A prospective crossover study design
- Fisheries governance in the face of climate change: Assessment of policy reform implications for Mexican fisheries
- Modeling sediment oxygen demand in a highly productive lake under various trophic scenarios
- Spread of domestic animals across Neolithic western Anatolia: New stable isotope evidence from Uğurlu Höyük, the island of Gökçeada, Turkey
- Relationship of the lobular branch of the great auricular nerve to the tympanoparotid fascia: Spatial anatomy for salvage during face and neck lift
- Assessing precision and requirements of three methods to estimate roe deer density
- Systematic review and REMARK scoring of renal cell carcinoma prognostic circulating biomarker manuscripts
- Assessing the potential of plains zebra to maintain African horse sickness in the Western Cape Province, South Africa
- Biomechanical effects of rocker shoes on plantar aponeurosis strain in patients with plantar fasciitis and healthy controls
- Age, body weight and ovarian function affect oocyte size and morphology in non-PCOS patients undergoing intracytoplasmic sperm injection (ICSI)
- RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance
- Gut microbiome diversity is associated with sleep physiology in humans
- Geospatial analysis of the influence of family doctor on colorectal cancer screening adherence
- Can machine learning improve patient selection for cardiac resynchronization therapy?
- The rotating magnetocaloric effect as a potential mechanism for natural magnetic senses
- Nutrigenomic effect of conjugated linoleic acid on growth and meat quality indices of growing rabbit
- Restriction enzymes use a 24 dimensional coding space to recognize 6 base long DNA sequences
- Hypoxia induction in cultured pancreatic islets enhances endothelial cell morphology and survival while maintaining beta-cell function
- Assessment of community knowledge, practice, and determinants of malaria case households in the rural area of Raya Azebo district, Northern Ethiopia, 2017
- Leadership in informal stormwater governance networks
- Early diagnosis of Alzheimer’s disease using combined features from voxel-based morphometry and cortical, subcortical, and hippocampus regions of MRI T1 brain images
- Health related quality of life in sepsis survivors from the Prehospital Antibiotics Against Sepsis (PHANTASi) trial
- The dialogue between protozoa and bacteria in a microfluidic device
- Are dialects socially learned in marmoset monkeys? Evidence from translocation experiments
- A new carcharodontosaurian theropod (Dinosauria: Saurischia) from the Lower Cretaceous of Thailand
- Using remote sensing to detect whale strandings in remote areas: The case of sei whales mass mortality in Chilean Patagonia
- Americans preferred Syrian refugees who are female, English-speaking, and Christian on the eve of Donald Trump’s election
- Class III β-tubulin expression as a predictor of docetaxel-resistance in metastatic castration-resistant prostate cancer
- Quantitative assessment of acetabular bone defects: A study of 50 computed tomography data sets
- HaTSPiL: A modular pipeline for high-throughput sequencing data analysis
- The feasibility of using citizens to segment anatomy from medical images: Accuracy and motivation
- Bacterial diversity in Icelandic cold spring sources and in relation to the groundwater amphipod Crangonyx islandicus
- Pathogen surveillance in the informal settlement, Kibera, Kenya, using a metagenomics approach
- Movement and habitat selection of the western spadefoot (Spea hammondii) in southern California
- African-American and Caucasian participation in postmortem human brain donation for neuropsychiatric research
- Two-dimensional fruit quality factors and soil nutrients reveals more favorable topographic plantation of Xinjiang jujubes in China
- The burden of oral conditions among adolescents living with HIV at a clinic in Johannesburg, South Africa
- The impact of peer pressure on cigarette smoking among high school and university students in Ethiopia: A systemic review and meta-analysis
- Substitution of marijuana for opioids in a national survey of US adults
- Strategies for the hypothermic preservation of cell sheets of human adipose stem cells
- Active hepatocellular carcinoma is an independent risk factor of direct-acting antiviral treatment failure: A retrospective study with prospectively collected data
- Microliths in the South Asian rainforest ~45-4 ka: New insights from Fa-Hien Lena Cave, Sri Lanka
- Transgenic cotton and farmers’ health in Pakistan
- Social media as a data resource for #monkseal conservation
- A novel short-term high-lactose culture approach combined with a matrix-assisted laser desorption ionization-time of flight mass spectrometry assay for differentiating Escherichia coli and Shigella species using artificial neural networks
- Common pre-diagnostic features in individuals with different rare diseases represent a key for diagnostic support with computerized pattern recognition?
- Automated clear cell renal carcinoma grade classification with prognostic significance
- Comparative genomic analyses reveal diverse virulence factors and antimicrobial resistance mechanisms in clinical Elizabethkingia meningoseptica strains
- Reading-out task variables as a low-dimensional reconstruction of neural spike trains in single trials
- ‘Fat’s chances’: Loci for phenotypic dispersion in plasma leptin in mouse models of diabetes mellitus
- Economic sanctions and academia: Overlooked impact and long-term consequences
- Evaluation of soybean genotypes for reaction to natural field infection by Cercospora species causing purple seed stain
- Trajectories of prescription opioids filled over time
- Quandong stones: A specialised Australian nut-cracking tool
- Tripeptide Arg-Gly-Asp (RGD) modifies the molecular mechanical properties of the non-muscle myosin IIA in human bone marrow-derived myofibroblasts seeded in a collagen scaffold
- Functional models in genome-wide selection
- Average volume reference space for large scale registration of whole-body magnetic resonance images
- Model based estimation of population total in presence of non-ignorable non-response
- ESLI: Enhancing slope one recommendation through local information embedding
- Self-adaptive dual-strategy differential evolution algorithm
- Projected urban growth in the southeastern USA puts small streams at risk
- Adverse prognosis of glioblastoma contacting the subventricular zone: Biological correlates
- Widespread chytrid infection across frogs in the Peruvian Amazon suggests critical role for low elevation in pathogen spread and persistence
- Dysfunction of the blood-brain barrier in postoperative delirium patients, referring to the axonal damage biomarker phosphorylated neurofilament heavy subunit
- A low latency and low power indirect topology for on-chip communication
- Development and application of a framework to estimate health care costs in China: The cervical cancer example
- New oral anti-coagulants versus vitamin K antagonists in high thromboembolic risk patients
- Enriched taxa were found among the gut microbiota of centenarians in East China
- Model-based QTL detection is sensitive to slight modifications in model formulation
- Modeling the residential distribution of enrolled students to assess boundary-induced disparities in public school access
- A brief diet intervention can reduce symptoms of depression in young adults – A randomised controlled trial
- Associations of MGMT promoter hypermethylation with squamous intraepithelial lesion and cervical carcinoma: A meta-analysis
- Differences in energy and nutritional content of menu items served by popular UK chain restaurants with versus without voluntary menu labelling: A cross-sectional study
- The association between disordered eating and health-related quality of life among children and adolescents: A systematic review of population-based studies
- Prescribing patterns of polypharmacy in Korean pediatric patients
- Factors associated with directly observed treatment in tuberculosis/HIV coinfection cases in Porto Alegre, 2009-2013: A retrospective cohort
- Evaluation of date palm pollen (Phoenix dactylifera L.) encapsulation, impact on the nutritional and functional properties of fortified yoghurt
- Association between maternal fermented food consumption and infant sleep duration: The Japan Environment and Children's Study
- Discerning the functional networks behind processing of music and speech through human vocalizations
- Preference-based serial decisions are counterintuitively influenced by emotion regulation and conscientiousness
- Subgenotyping and genetic variability of hepatitis C virus in Palestine
- Supra-threshold perception and neural representation of tones presented in noise in conditions of masking release
- Measuring sustainability of seed-funded earth science informatics projects
- Contrast-enhanced spectral mammography with a compact synchrotron source
- Assessing the role of toll-like receptor in isolated, standard and enriched housing conditions
- Inequality in income change among cancer survivors five years after diagnosis: Evidence from a French national survey
- A novel fast-slow model of diabetes progression: Insights into mechanisms of response to the interventions in the Diabetes Prevention Program
- Integrated HIV surveillance finds recent adult hepatitis B virus (HBV) transmission and intermediate HBV prevalence among military in uncharacterized Caribbean country
- Declared impact of the US President’s statements and campaign statements on Latino populations’ perceptions of safety and emergency care access
- Two novel and correlated CF-causing insertions in the (TG)mTn tract of the CFTR gene
- Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis
- Practice and factors associated with active management of third stage of labor among obstetric care providers in Amhara region referral hospitals, North Ethiopia, 2018: A cross sectional study
- Animal-assisted therapy for patients in a minimally conscious state: A randomized two treatment multi-period crossover trial
- Macular thickness measurements of healthy, naïve cynomolgus monkeys assessed with spectral-domain optical coherence tomography (SD-OCT)
- Rice bran oil ameliorates inflammatory responses by enhancing mitochondrial respiration in murine macrophages
- Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs
- The effect of ‘Traffic-Light’ nutritional labelling in carbonated soft drink purchases in Ecuador
- Forma mentis networks quantify crucial differences in STEM perception between students and experts
- A population-based cohort study examining the association of documented bladder diverticulum and bladder cancer risk in urology patients
- Framework for rational donor selection in fecal microbiota transplant clinical trials
- HLA high-resolution typing by next-generation sequencing in Pandemrix-induced narcolepsy
- Health assessment of Conolophus subcristatus, Conolophus pallidus, and C. subcristatus X Amblyrhynchus cristatus hybrid (Galápagos land iguanas)
- Prognostic value of post-induction chemotherapy 18F-FDG PET-CT in stage II/III non-small cell lung cancer before (chemo-) radiation
- Risk factor-based subphenotyping of heart failure in the community
- An efficient and adaptive data-hiding scheme based on secure random matrix
- Endovascular treatment of different types of iliac occlusions—Results from an observational study
- Variation in pickleweed root-associated microbial communities at different locations of a saline solid waste management unit contaminated with petroleum hydrocarbons
- Consumption of rice, acceptability and sensory qualities of fortified rice amongst consumers of social safety net rice in Nepal
- Quantitative analysis of the bilateral coordination and gait asymmetry using inertial measurement unit-based gait analysis
- Application of metagenomic shotgun sequencing to detect vector-borne pathogens in clinical blood samples
- Higher underestimation of tumour size post-neoadjuvant chemotherapy with breast magnetic resonance imaging (MRI)—A concordance comparison cohort analysis
- Wealth accumulation in rotation forestry – Failure of the net present value optimization?
- Increased incidence of age-related macular degeneration in sensorineural hearing loss: A population-based cohort study
- Evaluating the foundations that help avert antimicrobial resistance: Performance of essential water sanitation and hygiene functions in hospitals and requirements for action in Kenya
- Effects of a hot ambient operating theatre on manual dexterity, psychological and physiological parameters in staff during a simulated burn surgery
- Introduction of quality management in a National Reference Laboratory in Germany
- Histopathological investigation of complex gill disease in sea farmed Atlantic salmon
- Common variants in glyoxalase I do not increase chronic pancreatitis risk
- Cognitive impairment in multiple sclerosis: An exploratory analysis of environmental and lifestyle risk factors
- Japanese nationwide survey of hypophosphatasia reveals prominent differences in genetic and dental findings between odonto and non-odonto types
- Interaction of detergents with biological membranes: Comparison of fluorescence assays with filtration protocols and implications for the rates of detergent association, dissociation and flip-flop
- Potential causes of early death among admitted newborns in a rural Tanzanian hospital
- Identification of glomerular and podocyte-specific genes and pathways activated by sera of patients with focal segmental glomerulosclerosis
- Prevalence and correlates of partner violence among adolescent girls and young women: Evidence from baseline data of a cluster randomised trial in Tanzania
- Development of an integrated fingerstick blood self-collection device for radiation countermeasures
- Concordance between gene expression in peripheral whole blood and colonic tissue in children with inflammatory bowel disease
- Effects of arthroscopic vs. mini-open rotator cuff repair on function, pain & range of motion. A systematic review and meta-analysis
- Broiler welfare trade-off: A semi-quantitative welfare assessment for optimised welfare improvement based on an expert survey
- Engagement in care among women and their infants lost to follow-up under Option B+ in eSwatini
- Hyperglycemia in the early stages of type 1 diabetes accelerates gastric emptying through increased networks of interstitial cells of Cajal
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- A rapid, low pH, nutrient stress, assay to determine the bactericidal activity of compounds against non-replicating Mycobacterium tuberculosis
- Sialochemical analysis in polytraumatized patients in intensive care units
- The black sheep effect: The case of the deviant ingroup robot
- No relationship between fornix and cingulum degradation and within-network decreases in functional connectivity in prodromal Alzheimer’s disease
- Implementation of an international standardized set of outcome indicators in pregnancy and childbirth in Kenya: Utilizing mobile technology to collect patient-reported outcomes
- Breastfeeding support through wet nursing during nutritional emergency: A cross sectional study from Rohingya refugee camps in Bangladesh
- Does route matter? Impact of route of oxytocin administration on postpartum bleeding: A double-blind, randomized controlled trial
- Research on OpenCL optimization for FPGA deep learning application
- Drug therapy problems, medication adherence and treatment satisfaction among diabetic patients on follow-up care at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
- Quality of life and symptom intensity over time in people with cancer receiving palliative care: Results from the international European Palliative Care Cancer Symptom study
- The dynamics of Early Celtic consumption practices: A case study of the pottery from the Heuneburg
- Safety and efficacy of artesunate-amodiaquine combined with either methylene blue or primaquine in children with falciparum malaria in Burkina Faso: A randomized controlled trial
- “Cementing” marriages through childbearing in subsequent unions: Insights into fertility differentials among first-time married and remarried women in Ghana
- Single session high definition transcranial direct current stimulation to the cerebellum does not impact higher cognitive function
- The contribution of age structure to the international homicide decline
- Genetic structure of Mexican lionfish populations in the southwest Gulf of Mexico and the Caribbean Sea
- A physiological dose of oral vitamin B-12 improves hematological, biochemical-metabolic indices and peripheral nerve function in B-12 deficient Indian adolescent women
- Nutritional status, cognitive achievement, and educational attainment of children aged 8-11 in rural South India
- Costs and cost-effectiveness analyses of mCARE strategies for promoting care seeking of maternal and newborn health services in rural Bangladesh
- Cause-specific mortality in the general population with transient dipstick-proteinuria
- Assessing hand dysfunction in cervical spondylotic myelopathy
- KETOS: Clinical decision support and machine learning as a service – A training and deployment platform based on Docker, OMOP-CDM, and FHIR Web Services
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- Adjusting for spatial variation when assessing individual-level risk: A case-study in the epidemiology of snake-bite in Sri Lanka
- Acute sprint exercise transcriptome in human skeletal muscle
- Parenting and personality disorder: An overview and meta-synthesis of systematic reviews
- Female rats release a trapped cagemate following shaping of the door opening response: Opening latency when the restrainer was baited with food, was empty, or contained a cagemate
- Multiplex communities and the emergence of international conflict
- The impact of socioeconomic status on emergency department outcome in a low-income country setting: A registry-based analysis
- Effect of psycho-social support by teachers on improving mental health and hope of adolescents in an earthquake-affected district in Nepal: A cluster randomized controlled trial
- A cluster-randomized controlled trial of the effectiveness of the JUMP Math program of math instruction for improving elementary math achievement
- Transgenic mouse model for conditional expression of influenza hemagglutinin-tagged human SLC20A1/PIT1
- Use of rapid Model for End-Stage Liver Disease (MELD) increases for liver transplant registrant prioritization after MELD-Na and Share 35, an evaluation using data from the United Network for Organ Sharing
- Fishery Improvement Projects as a governance tool for fisheries sustainability: A global comparative analysis
- QRStree: A prefix tree-based model to fetal QRS complexes detection
- Fundraising and vote distribution: A non-equilibrium statistical approach
- Evaluation of PRRSv specific, maternally derived and induced immune response in Ingelvac PRRSFLEX EU vaccinated piglets in the presence of maternally transferred immunity
- Gene expression profiling of whole blood: A comparative assessment of RNA-stabilizing collection methods
- Alteration of adipose tissue immune cell milieu towards the suppression of inflammation in high fat diet fed mice by flaxseed oil supplementation
- Isoniazid preventive therapy: Uptake, incidence of tuberculosis and survival among people living with HIV in Bulawayo, Zimbabwe
- P16 methylation increases the sensitivity of cancer cells to the CDK4/6 inhibitor palbociclib
- Using long-term datasets to assess the impacts of dietary exposure to neonicotinoids on farmland bird populations in England
- Genetic mapping of distal femoral, stifle, and tibial radiographic morphology in dogs with cranial cruciate ligament disease
- Optimized bioluminescence analysis of adenosine triphosphate (ATP) released by platelets and its application in the high throughput screening of platelet inhibitors
- Consumer beliefs about healthy foods and diets
- An observational study on intracutaneous sodium storage in intensive care patients and controls
- Recovery when you are on your own: Slow population responses in an isolated marine reserve
- How does the method change what we measure? Comparing virtual reality and text-based surveys for the assessment of moral decisions in traffic dilemmas
- Is recent Afghanistan survey data suitable for fertility analysis? A regional investigation based on fertility inhibiting determinants
- Analytical validation of the Target Selector ctDNA platform featuring single copy detection sensitivity for clinically actionable EGFR, BRAF, and KRAS mutations
- Comparison of two swept-source optical coherence tomography biometers and a partial coherence interferometer
- Removal of anthracycline cytostatics from aquatic environment: Comparison of nanocrystalline titanium dioxide and decontamination agents
- A social media intervention to improve nutrition knowledge and behaviors of low income, pregnant adolescents and adult women
- Detection of vision and /or hearing loss using the interRAI Community Health Assessment aligns well with common behavioral vision/hearing measurements
- E-MOVIE - Experimental MOVies for Induction of Emotions in neuroscience: An innovative film database with normative data and sex differences
- Does self-reported pregnancy loss identify women at risk of an adverse cardiovascular phenotype in later life? Insights from UK Biobank
- An elevated glycemic gap predicts adverse outcomes in diabetic patients with necrotizing fasciitis
- 40-Hz auditory steady-state responses and the complex information processing: An exploratory study in healthy young males
- Highly diverse anaerobe-predominant vaginal microbiota among HIV-infected pregnant women in Zambia
- Decision-based models of the implementation of interventions in systems of healthcare: Implementation outcomes and intervention effectiveness in complex service environments
- Dual number-based variational data assimilation: Constructing exact tangent linear and adjoint code from nonlinear model evaluations
- Ultra-deep sequencing reveals pre-mRNA splicing as a sequence driven high-fidelity process
- Use of IoT sensing and occupant surveys for determining the resilience of buildings to forest fire generated PM2.5
- Classification of neurons in the adult mouse cochlear nucleus: Linear discriminant analysis
- Lek-associated movement of a putative Ebolavirus reservoir, the hammer-headed fruit bat (Hypsignathus monstrosus), in northern Republic of Congo
- Attenuation correction using 3D deep convolutional neural network for brain 18F-FDG PET/MR: Comparison with Atlas, ZTE and CT based attenuation correction
- Differences in macular capillary parameters between healthy black and white subjects with Optical Coherence Tomography Angiography (OCTA)
- Sealing agent reduces formation of single and dual-species biofilms of Candida albicans and Enterococcus faecalis on screw joints at the abutment/implant interface
- Chitotetraose activates the fungal-dependent endosymbiotic signaling pathway in actinorhizal plant species
- What is the optimum time for initiation of early mobilization in mechanically ventilated patients? A network meta-analysis
- Cognitive aptitude, peers, and trajectories of marijuana use from adolescence through young adulthood
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- Accuracy and interobserver-agreement of respiratory rate measurements by healthcare professionals, and its effect on the outcomes of clinical prediction/diagnostic rules
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- The Univariate Flagging Algorithm (UFA): An interpretable approach for predictive modeling
- Profiles and trajectories of impaired social cognition in people with Prader-Willi syndrome
- Effect of pimobendan on physical fitness, lactate and echocardiographic parameters in dogs with preclinical mitral valve disease without cardiomegaly
- Sub-types of safety behaviours and their effects on social anxiety disorder
- Engaging in prosocial behavior explains how high self-control relates to more life satisfaction: Evidence from three Chinese samples
- Artificial fingerprints for cross-comparison of forensic DNA and protein recovery methods
- The organization of Golgi in Drosophila bristles requires microtubule motor protein function and a properly organized microtubule array
- Direct and moderating effects of environmental regulation intensity on enterprise technological innovation: The case of China
- Prevalence and associated factors of depression among Korean adolescents
- Transcriptome analysis of PK-15 cells in innate immune response to porcine deltacoronavirus infection
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- Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury
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- Factors associated with exclusive breast-feeding: A cross-sectional survey in Kaiyuan, Yunnan, Southwest China
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- Refined distributed emotion vector representation for social media sentiment analysis
- Enhancing timeliness of drug overdose mortality surveillance: A machine learning approach
- A real-time gesture recognition system using near-infrared imagery
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- Improved survival rates in patients with H1N1 acute respiratory failure in Korea between 2009 and 2016
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- The Echobot: An automated system for stimulus presentation in studies of human echolocation
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- Agrobacterium tumefaciens-mediated transformation of a hevein-like gene into asparagus leads to stem wilt resistance
- Effect of a Mentor Mother Programme on retention of mother-baby pairs in HIV care: A secondary analysis of programme data in Uganda
- Utilizing multiplex fluor LAMPs to illuminate multiple gene expressions in situ
- Genetic relationships between the RACK1 homolog cpc-2 and heterotrimeric G protein subunit genes in Neurospora crassa
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- A comparison of the risk of congestive heart failure-related hospitalizations in patients receiving hemodialysis and peritoneal dialysis - A retrospective propensity score-matched study
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- Iodine supplementation of lactating women and assessment of infant visual information processing and maternal and infant thyroid function: A randomized trial
- The Nordic Maintenance Care Program: Does psychological profile modify the treatment effect of a preventive manual therapy intervention? A secondary analysis of a pragmatic randomized controlled trial
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- Comparison of conventional BLUP and single-step genomic BLUP evaluations for yearling weight and carcass traits in Hanwoo beef cattle using single trait and multi-trait models
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- Molecular phylogeny and morphology reveal a new epiphytic species of Habenaria (Orchidaceae; Orchideae; Orchidinae) from Nepal
- Nitrogen nutrition is a key modulator of the sugar and organic acid content in citrus fruit
- Understanding variation in health service coverage and maternal health outcomes among districts in Rwanda – A qualitative study of local health workers’ perceptions
- Biased cognition in East Asian and Western cultures
- Physical fitness and physical self-concept of male and female young adults in Qatar
- Robust policy evaluation from large-scale observational studies
- Improved semi-supervised autoencoder for deception detection
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- Are spasticity, weakness, selectivity, and passive range of motion related to gait deviations in children with spastic cerebral palsy? A statistical parametric mapping study
- ProphET, prophage estimation tool: A stand-alone prophage sequence prediction tool with self-updating reference database
- Conspicuous and cryptic reef fishes from a unique and economically important region in the northern Red Sea
- Time scale of resilience loss: Implications for managing critical transitions in water quality
- Effectiveness of physical and cognitive-behavioural intervention programmes for chronic musculoskeletal pain in adults: A systematic review and meta-analysis of randomised controlled trials
- Relationship between feed efficiency indexes and performance, body measurements, digestibility, energy partitioning, and nitrogen partitioning in pre-weaning dairy heifers
- Long-stay patients in pediatric intensive care unit: Diagnostic-specific definition and predictors
- Evidence of ritual breakage of a ground stone tool at the Late Natufian site of Hilazon Tachtit cave (12,000 years ago)
- Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease
- A systematic review and thematic synthesis of Canada’s LGBTQ2S+ employment, labour market and earnings literature
- The occurrence of ‘Sleeping Beauty’ publications in medical research: Their scientific impact and technological relevance
- Analysis of the protein composition of the spindle pole body during sporulation in Ashbya gossypii
- Assessing undergraduate student and faculty views on animal research: What do they know, whom do they trust, and how much do they care?
- The views and experiences of general dental practitioners (GDP’s) in West Yorkshire who used the International Caries Detection and Assessment System (ICDAS) in research
- Compare HIV/syphilis infections between age groups and explore associated factors of HIV/syphilis co-infections among men who have sex with men in Shenzhen, China, from 2009 to 2017
- Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers
- Effect of exclusive breastfeeding cessation time on childhood morbidity and adverse nutritional outcomes in Ethiopia: Analysis of the demographic and health surveys
- Dual antiplatelet therapy in patients with cirrhosis and acute myocardial infarction – A 13-year nationwide cohort study
- Relationships between electrolyte and amino acid compositions in sweat during exercise suggest a role for amino acids and K+ in reabsorption of Na+ and Cl- from sweat
- A simplified vocal tract model for articulation of [s]: The effect of tongue tip elevation on [s]
- Management and glycemic control of patients with type 2 diabetes mellitus at primary care level in Kedah, Malaysia: A statewide evaluation
- Anabolic steroids among resistance training practitioners
- Factors associated with unsafe abortion practices in Nepal: Pooled analysis of the 2011 and 2016 Nepal Demographic and Health Surveys
- New methods of removing debris and high-throughput counting of cyst nematode eggs extracted from field soil
- Vehicle configurations associated with anatomical-specific severe injuries resulting from traffic collisions
- What has reproductive health decision-making capacity got to do with unintended pregnancy? Evidence from the 2014 Ghana Demographic and Health Survey
- Circulating levels of CD34+ cells predict long-term cardiovascular outcomes in patients on maintenance hemodialysis
- Penetration of linezolid into bone tissue 24 h after administration in patients with multidrug-resistant spinal tuberculosis
- Prosthesis design of animal models of periprosthetic joint infection following total knee arthroplasty: A systematic review
- Coherent diversification in corporate technological portfolios
- Technology opportunity discovery by structuring user needs based on natural language processing and machine learning
- Effect of tranexamic acid administration on acute traumatic coagulopathy in rats with polytrauma and hemorrhage
- Factors associated with the use of diet and the use of exercise for prostate cancer by long-term survivors
- Congenital Zika Syndrome in a Brazil-Paraguay-Bolivia border region: Clinical features of cases diagnosed between 2015 and 2018
- Trends and impact of antimicrobial resistance on older inpatients with urinary tract infections (UTIs): A national retrospective observational study
- Malawian children with uncomplicated and cerebral malaria have decreased activated Vγ9Vδ2 γδ T cells which increase in convalescence
- Predictors of mortality within the first year of initiating antiretroviral therapy in urban and rural Kenya: A prospective cohort study
- The investment case as a mechanism for addressing the NCD burden: Evaluating the NCD institutional context in Jamaica, and the return on investment of select interventions
- Design, synthesis, and structural elucidation of novel NmeNANAS inhibitors for the treatment of meningococcal infection
- Bringing fear into focus: The intersections of HIV and masculine gender norms in Côte d’Ivoire
- Scientific output scales with resources. A comparison of US and European universities
- Transplanted spleen stromal cells with osteogenic potential support ectopic myelopoiesis
- Effect of host genotype and Eimeria acervulina infection on the metabolome of meat-type chickens
- Gravity influences bevacizumab distribution in an undisturbed balanced salt solution in vitro
- Agrobacterium tumefaciens-mediated transformation and expression of GFP in Ascochyta lentis to characterize ascochyta blight disease progression in lentil
- Proteomic changes of aryl hydrocarbon receptor (AhR)-silenced porcine granulosa cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
- Localization and dynamic change of saponins in Cyclocarya paliurus (Batal.) Iljinskaja
- Improving the forecasting performance of temporal hierarchies
- Prevalence of surgically correctable conditions among children in a mixed urban-rural community in Nigeria using the SOSAS survey tool: Implications for paediatric surgical capacity-building
- Relatives’ attachment anxiety mediates the association between perceived loss and expressed emotion in early psychosis
- The impact of PEPFAR transition on HIV service delivery at health facilities in Uganda
- Impact of peri-intraventricular haemorrhage and periventricular leukomalacia in the neurodevelopment of preterms: A systematic review and meta-analysis
- Correction: Activation of aryl hydrocarbon receptor signaling by a novel agonist ameliorates autoimmune encephalomyelitis
- Macrophage PPAR-γ suppresses long-term lung fibrotic sequelae following acute influenza infection
- Determination of factors affecting medication adherence in type 2 diabetes mellitus patients using a nationwide claim-based database in Japan
- Beyond the metabolic syndrome: Visceral and marrow adipose tissues impair bone quantity and quality in Cushing’s disease
- Clade II Candida auris possess genomic structural variations related to an ancestral strain
- Effect of aging on the association between ankle muscle strength and the control of bipedal stance
- Dietary polyphenols as a safe and novel intervention for modulating pain associated with intervertebral disc degeneration in an in-vivo rat model
- Kinematic and electromyographic analysis of variations in Nordic hamstring exercise
- Comparison of transcriptomes of an orthotospovirus vector and non-vector thrips species
- Trabeculectomy followed by phacoemulsification versus trabeculectomy alone: The Collaborative Bleb-Related Infection Incidence and Treatment Study
- Whole genome resequencing of watermelons to identify single nucleotide polymorphisms related to flesh color and lycopene content
- Religious practices and long-term survival after hospital discharge for an acute coronary syndrome
- Behavioral recovery and spinal motoneuron remodeling after polyethylene glycol fusion repair of singly cut and ablated sciatic nerves
- Platelets modulate multiple markers of neutrophil function in response to in vitro Toll-like receptor stimulation
- Comparative characterization of bacterial communities in geese consuming of different proportions of ryegrass
- Temperature sensitivity patterns of carbon and nitrogen processes in decomposition of boreal organic soils – Quantification in different compounds and molecule sizes based on a multifactorial experiment
- Cows painted with zebra-like striping can avoid biting fly attack
- The intriguing effect of ethanol and nicotine on acetylcholine-sensitive potassium current IKAch: Insight from a quantitative model
- The accumulation of deficits approach to describe frailty
- Botulinum toxin A injection into the entopeduncular nucleus improves dynamic locomotory parameters in hemiparkinsonian rats
- Turing complete neural computation based on synaptic plasticity
- Influence of mydriasis on optical coherence tomography angiography imaging in patients with age-related macular degeneration
- Specialized care improves outcomes for patients with cirrhosis who require general surgical operations
- Association between plural legal systems and sexual and reproductive health outcomes for women and girls in Nigeria: A state-level ecological study
- 3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
- Utility of qSOFA and modified SOFA in severe malaria presenting as sepsis
- Correction: Perspectives of general dental practitioners on preventive, patient-centred, and evidence-based oral healthcare—A Q-methodology study
- Early detection and differential serodiagnosis of Mycoplasma hyorhinis and Mycoplasma hyosynoviae infections under experimental conditions
- No evidence of associations between ADHD and event-related brain potentials from a continuous performance task in a population-based sample of adolescent twins
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- Simultaneous cardiac and respiratory inhibition during seizure precedes death in the DBA/1 audiogenic mouse model of SUDEP
- Dopamine receptor antagonists effects on low-dimensional attractors of local field potentials in optogenetic mice
- Cell-free DNA levels of twins and sibling pairs indicate individuality and possible use as a personalized biomarker
- Dinosaur ichnology and sedimentology of the Chignik Formation (Upper Cretaceous), Aniakchak National Monument, southwestern Alaska; Further insights on habitat preferences of high-latitude hadrosaurs
- Mechanical effects of MitraClip on leaflet stress and myocardial strain in functional mitral regurgitation – A finite element modeling study
- Catastrophic factors involved in road accidents: Underlying causes and descriptive analysis
- Seroprevalence of anti-Toxoplasma gondii antibodies in wild boars (Sus scrofa), hunting dogs, and hunters of Brazil
- Detection and determination of stability of the antibiotic residues in cow’s milk
- Neural minimization methods (NMM) for solving variable order fractional delay differential equations (FDDEs) with simulated annealing (SA)
- Maternal and perinatal outcomes among women with hypertensive disorders in pregnancy in Kumasi, Ghana
- Characteristics and costs in adults with acute poisoning admitted to the emergency department of a university hospital in Belgium
- War pact model of shrinking networks
- Treatment outcomes based on radiation therapy fields for bifocal germinoma: Synchronous or disseminated disease?
- Effect of an intensive 3-day social cognitive treatment (can do treatment) on control self-efficacy in patients with relapsing remitting multiple sclerosis and low disability: A single-centre randomized controlled trial
- Successful development of methodology for detection of hapten-specific contact hypersensitivity (CHS) memory in swine
- Postural changes in optic nerve and optic nerve sheath diameters in postural orthostatic tachycardia syndrome and spontaneous intracranial hypotension: A cohort study
- Attitudes and referral practices for pre-exposure prophylaxis (PrEP) among HIV rapid testers and case managers in Philadelphia: A mixed methods study
- The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study
- Endovascular therapy of direct dural carotid cavernous fistulas – A therapy assessment study including long-term follow-up patient interviews
- Frozen by stress: Stress increases scope insensitivity
- An extinction event in planktonic Foraminifera preceded by stabilizing selection
- Optimal seismic retrofitting techniques for URM school buildings located in the southwestern Iberian peninsula
- The effect of a hiding box on stress levels and body weight in Dutch shelter cats; a randomized controlled trial
- Early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: A systematic review and meta-analysis
- Deep brain activation patterns involved in virtual gait without and with a doorway: An fMRI study
- Infant dietary intake of yogurt and cheese and gastroenteritis at 1 year of age: The Japan Environment and Children’s Study
- Attenuation of renal fibrosis after unilateral ureteral obstruction in mice lacking the N-type calcium channel
- Anesthesia during deployment of a military forward surgical unit in low income countries: A register study of 1547 anesthesia cases
- CsBZIP40, a BZIP transcription factor in sweet orange, plays a positive regulatory role in citrus bacterial canker response and tolerance
- Differences in perceived popularity and social preference between bullying roles and class norms
- Identity and pathogenicity of some fungi associated with hazelnut (Corylus avellana L.) trunk cankers in Oregon
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- Associations between focus constructions and levels of exhaustivity: An experimental investigation of Chinese
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- Give science and peace a chance: Speeches by Nobel laureates in the sciences, 1901-2018
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- Adaptation of H3N2 canine influenza virus to feline cell culture
- A meta-analysis of crop response patterns to nitrogen limitation for improved model representation
- Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner
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- Transforming growth factor beta 1 induces methylation changes in lung fibroblasts
- Hepatic disease and the risk of mortality of Vibrio vulnificus necrotizing skin and soft tissue infections: A systematic review and meta-analysis
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- Large-scale phylogenomic analysis suggests three ancient superclades of the WUSCHEL-RELATED HOMEOBOX transcription factor family in plants
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- A cross sectional comparison of drug use indicators using WHO methodology in primary level hospitals participating in an Auditable Pharmaceutical Transactions and Services program versus non-APTS primary hospitals in Southern Ethiopia
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- Reporting biases in self-assessed physical and cognitive health status of older Europeans
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- First-line treatments in EGFR-mutated advanced non-small cell lung cancer: A network meta-analysis
- In vivo human lower limb muscle architecture dataset obtained using diffusion tensor imaging
- Tobacco smoke exposure as a risk factor for human papillomavirus infections in women 18-26 years old in the United States
- The trigger-information-response model: Exploring health literacy during the first six months following a kidney transplantation
- Factors influencing the behaviour and perceptions of Australian veterinarians towards antibiotic use and antimicrobial resistance
- The development of an evidence-based street food vending model within a socioecological framework: A guide for African countries
- Sociodemographic changes and trends in the rates of new perinatal HIV diagnoses and transmission in Spain from 1997 to 2015
- Patient navigation services for cancer care in low-and middle-income countries: A scoping review
- Weather extremes and perinatal mortality – Seasonal and ethnic differences in northern Sweden, 1800-1895
- Cognitive, relational and task crafting: Spanish adaptation and analysis of psychometric properties of the Job Crafting Questionnaire
- Maternal and perinatal death surveillance and response in Ethiopia: Achievements, challenges and prospects
- Identification and characterisation of capidermicin, a novel bacteriocin produced by Staphylococcus capitis
- Joint emulation of Earth System Model temperature-precipitation realizations with internal variability and space-time and cross-variable correlation: fldgen v2.0 software description
- Extensive culturomics of 8 healthy samples enhances metagenomics efficiency
- Macroepidemiological aspects of porcine reproductive and respiratory syndrome virus detection by major United States veterinary diagnostic laboratories over time, age group, and specimen
- Correction: Low dose naltrexone: Effects on medication in rheumatoid and seropositive arthritis. A nationwide register-based controlled quasi-experimental before-after study
- Correction: Human indole(ethyl)amine-N-methyltransferase (hINMT) catalyzed methylation of tryptamine, dimethylsulfide and dimethylselenide is enhanced under reducing conditions - A comparison between 254C and 254F, two common hINMT variants
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- Quantitation of eumelanin and pheomelanin markers in diverse biological samples by HPLC-UV-MS following solid-phase extraction
- Kinetics of mean platelet volume predicts mortality in patients with septic shock
- An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug resistance in high grade pancreatic ductal adenocarcinoma
- Combining CDK4/6 inhibitors ribociclib and palbociclib with cytotoxic agents does not enhance cytotoxicity
- Association of Medicaid expansion with health insurance coverage by marital status and sex
- Are current approaches for measuring access to clean water and sanitation inclusive of people with disabilities? Comparison of individual- and household-level access between people with and without disabilities in the Tanahun district of Nepal
- A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage
- Monitoring Universal Health Coverage (UHC) in high Tuberculosis burden countries: Tuberculosis mortality an important tracer of UHC service coverage
- RCT evaluation of Skhokho: A holistic school intervention to prevent gender-based violence among South African Grade 8s
- On the use of Action Units and fuzzy explanatory models for facial expression recognition
- A systematic review of complementary and alternative medicine in oncology: Psychological and physical effects of manipulative and body-based practices
- What factors best explain attitudes to snow leopards in the Nepal Himalayas?
- Determinants of temperature sensitivity of soil respiration with the decline of a foundation species
- Mindfulness meditation, time judgment and time experience: Importance of the time scale considered (seconds or minutes)
- Regional, institutional, and departmental factors associated with gender diversity among BS-level chemical and electrical engineering graduates
- Transepithelial transport of P-glycoprotein substrate by the Malpighian tubules of the desert locust
- Sex affects immunolabeling for histone 3 K27me3 in the trophectoderm of the bovine blastocyst but not labeling for histone 3 K18ac
- A survey of public attitudes toward uterus transplantation, surrogacy, and adoption in Japan
- Replacing plasma membrane outer leaflet lipids with exogenous lipid without damaging membrane integrity
- Accurate dried blood spots collection in the community using non-medically trained personnel could support scaling up routine viral load testing in resource limited settings
- Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study
- Antimicrobial efficacy of commercially available endodontic bioceramic root canal sealers: A systematic review
- The motility-based swim-up technique separates bull sperm based on differences in metabolic rates and tail length
- Synbiotic supplementation to decrease Salmonella colonization in the intestine and carcass contamination in broiler birds
- Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease
- States with higher minimum wages have lower STI rates among women: Results of an ecological study of 66 US metropolitan areas, 2003-2015
- Weakening the subjective sensation of own hand ownership does not interfere with rapid finger movements
- Identification of DNA methyltransferases and demethylases in Solanum melongena L., and their transcription dynamics during fruit development and after salt and drought stresses
- Environmental conditions for Jamestown Canyon virus correlated with population-level resource selection by white-tailed deer in a suburban landscape
- The contribution of linear perspective cues and texture gradients in the perceptual rescaling of stimuli inside a Ponzo illusion corridor
- Cerebral blood flow imbalance is associated with motor outcome after pediatric arterial ischemic stroke
- Particularly neglected in countries with other challenges: High Toxoplasma gondii seroprevalence in pregnant women in Kabul, Afghanistan, while a low proportion know about the parasite
- Implementing advance care planning in routine nursing home care: The development of the theory-based ACP+ program
- Identifying genetic lineages through shape: An example in a cosmopolitan marine turtle species using geometric morphometrics
- The causality of borrowing: Lexical loans in Eurasian languages
- The uptake of the pharmacy-dispensed naloxone kit program in Ontario: A population-based study
- Gaze and body cues interplay during interactive requests
- Acetylcholine-mediated top-down attention improves the response to bottom-up inputs by deformation of the attractor landscape
- Deep architectures for long-term stock price prediction with a heuristic-based strategy for trading simulations
- Vaccination status of patients using anti-TNF therapy and the physicians’ behavior shaping the phenomenon: Mixed-methods approach
- Organizational justice and illness reporting among Japanese employees with chronic diseases
- CavBench: A benchmark for protein cavity detection methods
- Antimicrobial resistance (AMR) and molecular characterization of Neisseria gonorrhoeae in Ghana, 2012-2015
- Prevalence of methicillin-resistant Staphylococcus aureus in healthy Chinese population: A system review and meta-analysis
- Suppression treatment differentially influences the microbial community and the occurrence of broad host range plasmids in the rhizosphere of the model cover crop Avena sativa L.
- Risk of pneumonia among residents living near goat and poultry farms during 2014-2016
- Lipid levels after childbirth and association with number of children: A population-based cohort study
- Birth outcomes in women who have taken adalimumab in pregnancy: A prospective cohort study
- ECMO with vasopressor use during early endotoxic shock: Can it improve circulatory support and regional microcirculatory blood flow?
- Effects of dietary intake and nutritional status on cerebral oxygenation in patients with chronic kidney disease not undergoing dialysis: A cross-sectional study
- Micro-RNA 150-5p predicts overt heart failure in patients with univentricular hearts
- Flexible learning spaces facilitate interaction, collaboration and behavioural engagement in secondary school
- Clinical significance and prognostic role of hypoxia-induced microRNA 382 in gastric adenocarcinoma
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- Classifying recurrent Mycobacterium tuberculosis cases in Georgia using MIRU-VNTR typing
- Prevalence of Trypanosoma cruzi infection in active military population of The Colombian National Army gathered in five departments
- An observational study comparing HPV prevalence and type distribution between HPV-vaccinated and -unvaccinated girls after introduction of school-based HPV vaccination in Norway
- Sarcopenia as a prognostic factor for survival in patients with locally advanced gastroesophageal adenocarcinoma
- Increased aggression and reduced aversive learning in honey bees exposed to extremely low frequency electromagnetic fields
- Attending to design when developing complex health interventions: A qualitative interview study with intervention developers and associated stakeholders
- Increased fecundity of Aphis fabae on Vicia faba plants following seed or leaf inoculation with the entomopathogenic fungus Beauveria bassiana
- Is summer food intake a limiting factor for boreal browsers? Diet, temperature, and reproduction as drivers of consumption in female moose
- Characterization of sound scattering layers in the Bay of Biscay using broadband acoustics, nets and video
- Conducting human challenge studies in LMICs: A survey of researchers and ethics committee members in Thailand
- eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization
- Clinical use of SAND battery to evaluate language in patients with Progressive Supranuclear Palsy
- The interplay of personality and attitudes toward own aging across two decades of later life
- Robust automated reading of the skin prick test via 3D imaging and parametric surface fitting
- Reconstructing the population history of the sandy beach amphipod Haustorioides japonicus using the calibration of demographic transition (CDT) approach
- A psychoacoustic application for the adjustment of electrical hearing thresholds in cochlear implant patients
- Correction: Blue light-dependent human magnetoreception in geomagnetic food orientation
- Re-evaluation of a Tn5::gacA mutant of Pseudomonas syringae pv. tomato DC3000 uncovers roles for uvrC and anmK in promoting virulence
- Sugar-sweetened beverages and colorectal cancer risk in the California Teachers Study
- Illuminating biological pathways for drug targeting in head and neck squamous cell carcinoma
- The impact of shared knowledge on speakers’ prosody
- Effects of insecticides, fipronil and imidacloprid, on the growth, survival, and behavior of brown shrimp Farfantepenaeus aztecus
- Prevalence of pectus excavatum (PE), pectus carinatum (PC), tracheal hypoplasia, thoracic spine deformities and lateral heart displacement in thoracic radiographs of screw-tailed brachycephalic dogs
- Validation of the vignette-based German Exercise Causality Orientation Scale (G-ECOS)
- Hierarchical classification of snowmelt episodes in the Pyrenees using seismic data
- A national survey of videolaryngoscopes and alternative intubation devices in Hungary
- The relevance of U.S. Strategic Highway Safety Plans in a future context
- Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs
- Anti-inflammatory effects induced by ultralow concentrations of bupivacaine in combination with ultralow concentrations of sildenafil (Viagra) and vitamin D3 on inflammatory reactive brain astrocytes
- Access to unauthorized hepatitis C generics: Perception and knowledge of physicians, pharmacists, patients and non-healthcare professionals
- Urban commuting dynamics in response to public transit upgrades: A big data approach
- Intestinal mucosal injury induced by obstructive jaundice is associated with activation of TLR4/TRAF6/NF-κB pathways
- When resolution does matter: Modelling indirect contacts in dairy farms at different levels of detail
- Molecular epidemiology of Mycoplasma hyorhinis porcine field isolates in the United States
- Liquorice ingestion attenuates vasodilatation via exogenous nitric oxide donor but not via β2-adrenoceptor stimulation
- Adolescents living with HIV are at higher risk of death and loss to follow up from care: Analysis of cohort data from eight health facilities in Ethiopia
- Identification of social relation within pedestrian dyads
- Blood donation and health status based on SF-36: The mediating effect of cognition in blood donation
- The cost-effectiveness of controlling cervical cancer using a new 9-valent human papillomavirus vaccine among school-aged girls in Australia
- Inactivation of chronic wasting disease prions using sodium hypochlorite
- Analysing linear multivariate pattern transformations in neuroimaging data
- Ecological aesthetic assessment of a rebuilt wetland restored from farmland and management implications for National Wetland Parks
- A method for predicting background advertisement exposure parameters in sporting events: Televised football game approach
- Self-reported and experimentally induced self-disgust is heightened in Parkinson’s disease: Contribution of behavioural symptoms
- Associations between nocturnal sleep duration, midday nap duration and body composition among adults in Southwest China
- Short-term effects of video gaming on brain response during working memory performance
- Molecular detection and genetic characterization of Bartonella species from rodents and their associated ectoparasites from northern Tanzania
- Estimation of the number of HCV-positive patients in Italy
- Comparative cost analysis of point-of-care versus laboratory-based testing to initiate and monitor HIV treatment in South Africa
- Insights into the behavior of six rationally designed peptides based on Escherichia coli’s OmpA at the water-dodecane interface
- Identification of muscle-specific candidate genes in Simmental beef cattle using imputed next generation sequencing
- A game theoretic setting of capitation versus fee-for-service payment systems
- In utero exposure to economic fluctuations and birth outcomes: An analysis of the relevance of the local unemployment rate in Brazilian state capitals
- QTL mapping for aluminum tolerance in RIL population of soybean (Glycine max L.) by RAD sequencing
- Establishing an infrastructure for collaboration in primate cognition research
- Evaluation of left ventricular dimension and systolic function by standard transthoracic echocardiography before and 24-hours after percutaneous closure of patent ductus arteriosus in 120 dogs
- Modeling environmental variability and network formation among pastoral nomadic households: Implications for the rise of the Mongol Empire
- Changes in real-life practice for hepatocellular carcinoma patients in the Republic of Korea over a 12-year period: A nationwide random sample study
- Correction: Homology analysis of malware based on ensemble learning and multifeatures
- Illness beliefs and emotional responses in mildly disabled stroke survivors: A qualitative study
- Extended-wavelength diffuse reflectance spectroscopy with a machine-learning method for in vivo tissue classification
- Modeling the natural history of fatty liver using lifestyle–related risk factors: Effects of body mass index (BMI) on the life–course of fatty liver
- Development of a recombinant replication-deficient rabies virus-based bivalent-vaccine against MERS-CoV and rabies virus and its humoral immunogenicity in mice
- Educational achievement at age 9.5 years of children born to mothers maintained on methadone during pregnancy
- Comparative transcriptome analysis of galls from four different host plants suggests the molecular mechanism of gall development
- Experiences with peer support for breastfeeding in Beirut, Lebanon: A qualitative study
- Elucidating optical field directed hierarchical self-assembly of homogenous versus heterogeneous nanoclusters with femtosecond optical tweezers
- Structure establishment of three-dimensional (3D) cell culture printing model for bladder cancer
- Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality
- Correction: Functional atlases for analysis of motor and neuropsychological outcomes after medial globus pallidus and subthalamic stimulation
- Correction: Estimating Body Composition in Adolescent Sprint Athletes: Comparison of Different Methods in a 3 Years Longitudinal Design
- Quality of labor and birth care in Sindh Province, Pakistan: Findings from direct observations at health facilities
- A comparison of sLASER and MEGA-sLASER using simultaneous interleaved acquisition for measuring GABA in the human brain at 7T
- Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis
- Intrabladder pressure as predictor of intra-abdominal pressure in horses
- Pollock avoided hydrodynamic instabilities to paint with his dripping technique
- Metabolomic analysis of the occurrence of bitter fruits on grafted oriental melon plants
- Photo-degradation dynamics of five neonicotinoids: Bamboo vinegar as a synergistic agent for improved functional duration
- Use of acoustic emission to identify novel candidate biomarkers for knee osteoarthritis (OA)
- Cetacean biodiversity, spatial and temporal trends based on stranding records (1920-2016), Victoria, Australia
- Neutrophil elastase inhibitor purification strategy from cowpea seeds
- Correction: Hafting of Middle Paleolithic tools in Latium (central Italy): New data from Fossellone and Sant’Agostino caves
- Coherent poly propagation materials with 3-dimensional photonic control over visible light
- Characterization of Worldwide Olive Germplasm Banks of Marrakech (Morocco) and Córdoba (Spain): Towards management and use of olive germplasm in breeding programs
- Can non-pharmacological interventions reduce hospital admissions in people with dementia? A systematic review
- Metarhizium robertsii ammonium permeases (MepC and Mep2) contribute to rhizoplane colonization and modulates the transfer of insect derived nitrogen to plants
- Genotyping and antimicrobial resistance of Streptococcus uberis isolated from bovine clinical mastitis
- Isotopic compositions of ground ice in near-surface permafrost in relation to vegetation and microtopography at the Taiga–Tundra boundary in the Indigirka River lowlands, northeastern Siberia
- Financial inclusion and intimate partner violence: What does the evidence suggest?
- Are intestinal helminths playing a positive role in tuberculosis risk? A systematic review and meta-analysis
- Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition
- Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer
- Take one step backward to move forward: Assessment of genetic diversity and population structure of captive Asian woolly-necked storks (Ciconia episcopus)
- Money doesn’t matter! Householders’ intentions to reduce standby power are unaffected by personalised pecuniary feedback
- Validating a scale to measure engineers’ perceived self-efficacy for engineering education outreach
- Effect of d-cycloserine on fear extinction training in adults with social anxiety disorder
- Nursing students and nurses’ knowledge and attitudes regarding children’s pain: A comparative cross-sectional study
- Inter-method and anatomical correlates of episodic memory tests in the Alzheimer’s Disease spectrum
- Knowledge, attitudes and medical practice regarding hepatitis B prevention and management among healthcare workers in Northern Vietnam
- Development and validation of a symptom assessment tool for postmicturition dribble: A prospective, multicenter, observational study in Korea
- Identification of closely related Ixodes species by protein profiling with MALDI-TOF mass spectrometry
- When calculators lie: A demonstration of uncritical calculator usage among college students and factors that improve performance
- Socio-economic characteristics and career intentions of the WiSDOM health professional cohort in South Africa
- Correction: Neural computational model GrowthEstimate: A model for studying living resources through digestive efficiency
- Social proximity in dairy calves is affected by differences in pessimism
- Amphibian skin-associated Pigmentiphaga: Genome sequence and occurrence across geography and hosts
- Expanded consumer niche widths may signal an early response to spatial protection
- Moral grandstanding in public discourse: Status-seeking motives as a potential explanatory mechanism in predicting conflict
- Adipose stem cells in reparative goat mastitis mammary gland
- Seventy-five mosses and liverworts found frozen with the late Neolithic Tyrolean Iceman: Origins, taphonomy and the Iceman’s last journey
- Hyaluronic acid and epidermal growth factor improved the bovine embryo quality by regulating the DNA methylation and expression patterns of the focal adhesion pathway
- Associations among knowledge, attitudes, and practices toward palliative care consultation service in healthcare staffs: A cross-sectional study
- A novel, wearable, electronic visual aid to assist those with reduced peripheral vision
- Genetic diversity and population structure of the Mediterranean sesame core collection with use of genome-wide SNPs developed by double digest RAD-Seq
- Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression
- Mobile health-based physical activity intervention for individuals with spinal cord injury in the community: A pilot study
- Factors influencing cultivated ginseng (Panax ginseng C. A. Meyer) bioactive compounds
- Estimation of soil pH with geochemical indices in forest soils
- Multiplexed editing of a begomovirus genome restricts escape mutant formation and disease development
- Correlates of longitudinal leukocyte telomere length in the Costa Rican Longevity Study of Healthy Aging (CRELES): On the importance of DNA collection and storage procedures
- Collaboration and followership: A stochastic model for activities in social networks
- Evaluating access to oral anti-diabetic medicines: A cross-sectional survey of prices, availability and affordability in Shaanxi Province, Western China
- Comparison of corneal elevation and pachymetry measurements made by two state of the art corneal tomographers with different measurement principles
- Use of a pressure-sensing walkway system for biometric assessment of gait characteristics in goats
- Current status and direct medical cost of amyotrophic lateral sclerosis in the region of Catalonia: A population-based analysis
- Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion
- Can work climate foster pro-environmental behavior inside and outside of the workplace?
- Gene editing of PKLR gene in human hematopoietic progenitors through 5’ and 3’ UTR modified TALEN mRNA
- Pelvic alignment changes during the perinatal period
- Interatrial blocks prevalence and risk factors for human immunodeficiency virus-infected persons
- Life-course trajectories of body mass index and subsequent cardiovascular risk among Chinese population
- Inhibitory interaction networks among coevolved Streptomyces populations from prairie soils
- Exploiting contextual information to improve call prediction
- Visual inputs decrease brain activity in frontal areas during silent lipreading
- The synergistic effects of TaAGP.L-B1 and TaSSIVb-D mutations in wheat lead to alterations of gene expression patterns and starch content in grain development
- Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets
- Robust, real-time generic detector based on a multi-feature probabilistic method
- Maize leaves drought-responsive genes revealed by comparative transcriptome of two cultivars during the filling stage
- Xenon lamps used for fruit surface sterilization can increase the content of total flavonols in leaves of Lactuca sativa L. without any negative effect on net photosynthesis
- An alternative procedure to obtain the mortality rate with non-linear functions: Application to the case of the Spanish population
- Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis
- Longitudinal assessment of post-surgical physical activity in endometrial and ovarian cancer patients
- THINGS: A database of 1,854 object concepts and more than 26,000 naturalistic object images
- Evaluation of ranibizumab and aflibercept for the treatment of diabetic macular edema in daily clinical practice
- Proteomic analysis of Escherichia coli detergent-resistant membranes (DRM)
- Correction: Effect of curcuminoids and curcumin derivate products on thioredoxin-glutathione reductase from Taenia crassiceps cysticerci. Evidence suggesting a curcumin oxidation product as a suitable inhibitor
- Correction: Predicting childhood obesity using electronic health records and publicly available data
- Correction: Estimating the value of tropical coastal wetland habitats to fisheries: Caveats and assumptions
- Correction: The effects of sympathetic activity induced by ice water on blood flow and brachial artery flow-mediated dilatation response in healthy volunteers
- Determinants of frailty development and progression using a multidimensional frailty index: Evidence from the English Longitudinal Study of Ageing
- Supporting informed clinical trial decisions: Results from a randomized controlled trial evaluating a digital decision support tool for those with intellectual disability
- BMAL1 associates with chromosome ends to control rhythms in TERRA and telomeric heterochromatin
- Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry
- Hepatopulmonary syndrome has low prevalence of pulmonary vascular abnormalities on chest computed tomography
- Early and long-term outcomes of coronary artery bypass surgery with and without use of heart-lung machine and with special respect to renal function - A retrospective study
- Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15
- The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population
- Expression of Concern: The Coordination of Cell Growth during Fission Yeast Mating Requires Ras1-GTP Hydrolysis
- Correction: Lentivirus-Mediated Knockdown of Astrocyte Elevated Gene-1 Inhibits Growth and Induces Apoptosis through MAPK Pathways in Human Retinoblastoma Cells
- Relationship between self-disclosure to first acquaintances and subjective well-being in people with schizophrenia spectrum disorders living in the community
- Remarkable cell recovery from cerebral ischemia in rats using an adaptive escalator-based rehabilitation mechanism
- Integrating environmental and neighborhood factors in MaxEnt modeling to predict species distributions: A case study of Aedes albopictus in southeastern Pennsylvania
- Post-overdose interventions triggered by calling 911: Centering the perspectives of people who use drugs (PWUDs)
- The prevalence of intimate partner violence among couples signing up for universally offered parent preparation
- Analysis of gear surface morphology based on gray level co-occurrence matrix and fractal dimension
- Abiotic, present-day and historical effects on species, functional and phylogenetic diversity in dry grasslands of different age
- Clonality analysis of pulmonary tumors by genome-wide copy number profiling
- A relictual troglomorphic harvestman discovered in a volcanic cave of western Argentina: Otilioleptes marcelae, new genus, new species, and Otilioleptidae, new family (Arachnida, Opiliones, Gonyleptoidea)
- HIV drug resistance in persons who inject drugs enrolled in an HIV prevention trial in Indonesia, Ukraine, and Vietnam: HPTN 074
- Dietary acid load significantly predicts 10-years survival in patients underwent coronary artery bypass grafting (CABG) surgery
- Regulation of nitrogen availability results in changes in grain protein content and grain storage subproteomes in barley (Hordeum vulgare L.)
- Diagnostic test evaluation methodology: A systematic review of methods employed to evaluate diagnostic tests in the absence of gold standard – An update
- Longitudinal trends of and factors associated with inappropriate antibiotic prescribing for non-bacterial acute respiratory tract infection in Japan: A retrospective claims database study, 2012–2017
- Revealing users’ experience and social interaction outcomes following a web-based smoking prevention intervention for adolescents: A qualitative study
- Coordination of human movements resulting in motor strategies exploited by skilled players during a throwing task
- Impact of pericardiectomy on exercise capacity and sleep of patients with chronic constrictive pericarditis
- Blue-violet light decreases VEGFa production in an in vitro model of AMD
- Identification of protein changes in the blood plasma of lung cancer patients subjected to chemotherapy using a 2D-DIGE approach
- Speed of processing training and depression in assisted and independent living: A randomized controlled trial
- Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient
- What happens in the brain of meditators when perception changes but not the stimulus?
- Comparison of HIV-1 Vif and Vpu accessory proteins for delivery of polyepitope constructs harboring Nef, Gp160 and P24 using various cell penetrating peptides
- Are degree of urbanisation and travel times to healthcare services associated with the processes of care and outcomes of heart failure? A retrospective cohort study based on administrative data
- A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing
- Influence of transcutaneous vagus nerve stimulation on cardiac vagal activity: Not different from sham stimulation and no effect of stimulation intensity
- Co-prescription network reveals social dynamics of opioid doctor shopping
- Contractile properties of superficial skeletal muscle affect postural control in healthy young adults: A test of the rambling and trembling hypothesis
- Does intrauterine crowding affect the force generating capacity and muscle composition of the piglet front limb?
- Correction: Measuring compassionate healthcare with the 12-item Schwartz Center Compassionate Care Scale
- Facilitators and barriers to traditional medicine use among cancer patients in Malawi
- Expression of CMV protein pp65 in cutaneous malignant melanoma
- The evolution of mental health outcomes across a combat deployment cycle: A longitudinal study of a Guam-based National Guard unit
- Caesarean section delivery and childhood obesity in a British longitudinal cohort study
- Incidence, characteristics, and mortality of infective endocarditis in France in 2011
- Pfcyp51 exclusively determines reduced sensitivity to 14α-demethylase inhibitor fungicides in the banana black Sigatoka pathogen Pseudocercospora fijiensis
- Evaluation of the bacterial ocular surface microbiome in clinically normal cats before and after treatment with topical erythromycin
- Histological and developmental insights into the herbivorous dentition of tapinocephalid therapsids
- Differential immunomodulation of T-cells by immunoglobulin replacement therapy in primary and secondary antibody deficiency
- A longitudinal study on perceived health in cardiovascular patients: The role of conscientiousness, subjective wellbeing and cardiac self-efficacy
- The effectiveness of interferon beta versus glatiramer acetate and natalizumab versus fingolimod in a Polish real-world population
- Interactions of Streptococcus suis serotype 9 with host cells and role of the capsular polysaccharide: Comparison with serotypes 2 and 14
- Honey bee and native solitary bee foraging behavior in a crop with dimorphic parental lines
- A flexible formula for incorporating distributive concerns into cost-effectiveness analyses: Priority weights
- Correction: Lack of association between hypothyroxinemia of prematurity and transient thyroid abnormalities with adverse long term neurodevelopmental outcome in very low birth weight infants
- A reconnaissance survey of farmers’ awareness of hypomagnesaemic tetany in UK cattle and sheep farms
- Health workers’ perception of malaria rapid diagnostic test and factors influencing compliance with test results in Ebonyi state, Nigeria
- Conformational flexibility of fork-remodeling helicase Rad5 shown by full-ensemble hybrid methods
- The increasing importance of fellowships and career development awards in the careers of early-stage biomedical academic researchers
- Occurrence and stability of hetero-hexamer associations formed by β-carboxysome CcmK shell components
- Auxin driven indoleamine biosynthesis and the role of tryptophan as an inductive signal in Hypericum perforatum (L.)
- Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development
- Distance to large rivers affects fish diversity patterns in highly dynamic streams of Central Amazonia
- Real vs. immersive-virtual emotional experience: Analysis of psycho-physiological patterns in a free exploration of an art museum
- Modulation of brain tumor risk by genetic SNPs in PARP1gene: Hospital based case control study
- Processed meat intake and chronic disease morbidity and mortality: An overview of systematic reviews and meta-analyses
- Modeling ENSO impact on rice production in the Mekong River Delta
- The feasibility of a behavioral group intervention after weight-loss surgery: A randomized pilot trial
- EMR-integrated minimal core dataset for routine health care and multiple research settings: A case study for neuroinflammatory demyelinating diseases
- A review of a 13-month period of FilmArray Meningitis/Encephalitis panel implementation as a first-line diagnosis tool at a university hospital
- Increased BMI has a linear association with late-onset preeclampsia: A population-based study
- Autoantibody production significantly decreased with APRIL/BLyS blockade in murine chronic rejection kidney transplant model
- Vancomycin-resistance gene cluster, vanC, in the gut microbiome of acute leukemia patients undergoing intensive chemotherapy
- Telomere length in COPD: Relationships with physical activity, exercise capacity, and acute exacerbations
- Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP
- Impact of faecal calprotectin measurement on clinical decision-making in patients with Crohn’s disease and ulcerative colitis
- Additive effects of a small molecular PCNA inhibitor PCNA-I1S and DNA damaging agents on growth inhibition and DNA damage in prostate and lung cancer cells
- Autophagy is important to the acidogenic metabolism of Aspergillus niger
- Continuous ratings of movie watching reveal idiosyncratic dynamics of aesthetic enjoyment
- Sensitivity and specificity of serum soluble interleukin-2 receptor for diagnosing sarcoidosis in a population of patients suspected of sarcoidosis
- Enhancing genomic selection by fitting large-effect SNPs as fixed effects and a genotype-by-environment effect using a maize BC1F3:4 population
- Quantitation and modeling of post-translational modifications in a therapeutic monoclonal antibody from single- and multiple-dose monkey pharmacokinetic studies using mass spectrometry
- Microbial induced solidification and stabilization of municipal solid waste incineration fly ash with high alkalinity and heavy metal toxicity
- Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses
- A fault-tolerant aware scheduling method for fog-cloud environments
- Correction: BCG vaccination and tuberculosis prevention: A forty years cohort study, Monastir, Tunisia
- Correction: Perceptions among transgender women of factors associated with the access to HIV/AIDS-related health services in Yogyakarta, Indonesia
- Assessing the convergent validity between the automated emotion recognition software Noldus FaceReader 7 and Facial Action Coding System Scoring
- Deep learning based banana plant detection and counting using high-resolution red-green-blue (RGB) images collected from unmanned aerial vehicle (UAV)
- Comparison of cardiorespiratory fitness between preschool children with normal and excess body adipose ~ An observational study
- Intraregional differences in renal function in the Northern Netherlands: The Lifelines Cohort Study
- Effects of MCHM on yeast metabolism
- Signaling impacts of GMO labeling on fruit and vegetable demand
- Dietary specialization depending on ecological context and sexual differences in Asiatic black bears
- Electronic device use and beverage related sugar and caffeine intake in US adolescents
- Isolation and characterization of five novel probiotic strains from Korean infant and children faeces
- Correction: Silymarin in non-cirrhotics with non-alcoholic steatohepatitis: A randomized, double-blind, placebo controlled trial
- Correction: Anatomical analysis of antebrachial cutaneous nerve distribution pattern and its clinical implications for sensory reconstruction
- Endothelial nitric oxide synthase limits host immunity to control disseminated Candida albicans infections in mice
- Lack of detection of Candida nivariensis and Candida bracarensis among 440 clinical Candida glabrata sensu lato isolates in Kuwait
- Nonlinear dynamics captures brain states at different levels of consciousness in patients anesthetized with propofol
- Visual encounters on line transect surveys under-detect carnivore species: Implications for assessing distribution and conservation status
- Menstrual health communication among Indian adolescents: A mixed-methods study
- Fast fluorescence in situ hybridisation for the enhanced detection of MET in non-small cell lung cancer
- The influence of personality on the effect of iTBS after being stressed on cortisol secretion
- Parental and peer support and modelling in relation to domain-specific physical activity participation in boys and girls from Germany
- Oral delivery of water-soluble compounds to the phytoseiid mite Neoseiulus californicus (Acari: Phytoseiidae)
- Force perceptual bias caused by muscle activity in unimanual steering
- Correction: Comparison of risk models for mortality and cardiovascular events between machine learning and conventional logistic regression analysis
- Correction: Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium
- Providencia entomophila sp. nov., a new bacterial species associated with major olive pests in Tunisia
- Safety of intravitreal ziv-aflibercept in choroido-retinal vascular diseases: A randomised double-blind intervention study
- A novel framework for evaluating the impact of individual decision-making on public health outcomes and its potential application to study antiviral treatment collection during an influenza pandemic
- Reduction of the rocuronium-induced withdrawal reflex by MR13A10A, a generic rocuronium with a novel solution: A randomized, controlled study
- Emotionally expressed voices are retained in memory following a single exposure
- Megabenthic communities of the Ligurian deep continental shelf and shelf break (NW Mediterranean Sea)
- Election forensics: Using machine learning and synthetic data for possible election anomaly detection
- A randomized crossover trial comparing the Nifty cup to a medicine cup in preterm infants who have difficulty breastfeeding at Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana
- The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease
- Genomic impact of severe population decline in a nomadic songbird
- Evolution of high-sensitivity troponin-T and echocardiography parameters in patients undergoing high efficiency on-line hemodiafiltration versus conventional low-flux hemodialysis
- Full genome characterization of 12 citrus tatter leaf virus isolates for the development of a detection assay
- Intake of myo-inositol hexaphosphate and urinary excretion of inositol phosphates in Wistar rats: Gavage vs. oral administration with sugar
- Enhancing financial security of female sex workers through a community-led intervention in India: Evidence from a longitudinal survey
- In-silico prediction of novel genes responsive to drought and salinity stress tolerance in bread wheat (Triticum aestivum)
- Genetic diversification of Panstrongylus geniculatus (Reduviidae: Triatominae) in northern South America
- Partitioning the risk of tuberculosis transmission in household contact studies
- Recommendation system in social networks with topical attention and probabilistic matrix factorization
- Using satellite-measured relative humidity for prediction of Metisa plana’s population in oil palm plantations: A comparative assessment of regression and artificial neural network models
- A drug interaction study investigating the effect of Rifabutin on the pharmacokinetics of Maraviroc in healthy subjects
- Emotional and behavioral problems, social competence and risk factors in 6–16-year-old students in Beijing, China
- Clinicopathologic and prognostic significance of tumor-associated macrophages in patients with hepatocellular carcinoma: A meta-analysis
- Involution of retinopathy of prematurity and neurodevelopmental outcomes after intravitreal bevacizumab treatment
- Travel demand and distance analysis for free-floating car sharing based on deep learning method
- Genome-wide identification, characterization, expression and enzyme activity analysis of coniferyl alcohol acetyltransferase genes involved in eugenol biosynthesis in Prunus mume
- Population analysis of D6-like plasmid prophage variants associated with specific IncC plasmid types in the emerging Salmonella Typhimurium ST213 genotype
- The high resource impact of reformatting requirements for scientific papers
- Egg yolk-free cryopreservation of bull semen
- Fine epitope mapping of glycoprotein Gn in Guertu virus
- Are hospital nurse staffing practices associated with postoperative cardiac events and death? A systematic review
- Dysregulation of macrophage development and phenotype in diabetic human macrophages can be rescued by Hoxa3 protein transduction
- Aging and the wandering brain: Age-related differences in the neural correlates of stimulus-independent thoughts
- Elucidating stygofaunal trophic web interactions via isotopic ecology
- Experimental characterization of two archaeal inosine 5'-monophosphate cyclohydrolases
- Scientist and data architect collaborate to curate and archive an inner ear electrophysiology data collection
- No effect of triple-pulse TMS medial to intraparietal sulcus on online correction for target perturbations during goal-directed hand and foot reaches
- Correction: Controlling Social Stress in Virtual Reality Environments
- TNF-α is responsible for the contribution of stromal cells to osteoclast and odontoclast formation during orthodontic tooth movement
- Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children
- Alteration of humoral, cellular and cytokine immune response to inactivated influenza vaccine in patients with Sickle Cell Disease
- To tweet or not to tweet, that is the question: A randomized trial of Twitter effects in medical education
- Visualizing a field of research: A methodology of systematic scientometric reviews
- True Colors: Commercially-acquired morphological genotypes reveal hidden allele variation among dog breeds, informing both trait ancestry and breed potential
- Impact of the detection of ζ-globin chains and hemoglobin Bart’s using immunochromatographic strip tests for α0-thalassemia (--SEA) differential diagnosis
- Cognitive impairment and medication adherence post-stroke: A five-year follow-up of the ASPIRE-S cohort
- Correction: Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism
- Correction: Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana
- Correction: Precision public health: Mapping socioeconomic disparities in opioid dispensations at Swedish pharmacies by Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA)
- Epidemiological, clinical and laboratory characteristics of the measles resurgence in the Republic of Serbia in 2014-2015
- Macro-charcoal accumulation in floodplain wetlands: Problems and prospects for reconstruction of fire regimes and environmental conditions
- Stage at diagnosis and stage-specific survival of breast cancer in Latin America and the Caribbean: A systematic review and meta-analysis
- Correction: Retraction: Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway
- TEM8/ANTXR1-specific CAR T cells mediate toxicity in vivo
- Clinical impact of intraoperative hyperlactatemia during craniotomy
- Intubation with channeled versus non-channeled video laryngoscopes in simulated difficult airway by junior doctors in an out-of-hospital setting: A crossover manikin study
- Age and growth of stocked juvenile Shoal Bass in a tailwater: Environmental variation and accuracy of daily age estimates
- Sex-specific differences in risk factors of lymph node metastasis in patients with early gastric cancer
- The impact of electroconvulsive therapy on the spatial QRS-T angle and cardiac troponin T concentration in psychiatric patients
- BDNF, NT-3 and Trk receptor agonist monoclonal antibodies promote neuron survival, neurite extension, and synapse restoration in rat cochlea ex vivo models relevant for hidden hearing loss
- Investigation on the hereditary basis of colorectal cancers in an African population with frequent early onset cases
- Comparison of cancer prevalence between patients with glomerulonephritis and the general population at the time of kidney biopsy
- Predictors of time to unfavorable treatment outcomes among patients with multidrug resistant tuberculosis in Oromia region, Ethiopia
- Experimentally validated simulation of coronary stents considering different dogboning ratios and asymmetric stent positioning
- The membrane effects of melittin on gastric and colorectal cancer
- Exclusive breastfeeding policy, practice and influences in South Africa, 1980 to 2018: A mixed-methods systematic review
- Hippocampal subfield volumes and pre-clinical Alzheimer’s disease in 408 cognitively normal adults born in 1946
- Uncorrected low hyperopia in young subjects induces postural instability even in those with clear visual acuity
- Membrane associated proteins of two Trichomonas gallinae clones vary with the virulence
- Awareness, current use of electronic cigarettes and associated smoking factors in Zhejiang Chinese adolescents
- Associations between pre-pregnancy BMI, gestational weight gain, and prenatal diet quality in a national sample
- Effects of continuous ketamine infusion on hemodynamics and mortality in critically ill children
- Optofluidic laser speckle image decorrelation analysis for the assessment of red blood cell storage
- Complete chloroplast genome sequence and phylogenetic analysis of Spathiphyllum 'Parrish'
- Strategic science communication as planned behavior: Understanding scientists’ willingness to choose specific tactics
- Understanding spatial patterns of soils for sustainable agriculture in northern Ethiopia’s tropical mountains
- Does Japan’s national nutrient-based dietary guideline improve lifestyle-related disease outcomes? A retrospective observational cross-sectional study
- Agitation near the end of life with dementia: An ethnographic study of care
- Tick-borne encephalitis virus infections in Germany. Seasonality and in-year patterns. A retrospective analysis from 2001-2018
- Encouraging perspective taking: Using narrative writing to induce empathy for others engaging in negative health behaviors
- Considerations of target surface area and the risk of radiosurgical toxicity
- Correction: A comparative study of RNA-Seq and microarray data analysis on the two examples of rectal-cancer patients and Burkitt Lymphoma cells
- Effect of using immobilization device in fluoroscopic study in pediatric patient: Focused on radiation dose reduction in voiding cystourethrogram
- Temporal trends in breast cancer survival by race and ethnicity: A population-based cohort study
- Contamination of hospital surfaces with respiratory pathogens in Bangladesh
- The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-based oxygen carrier: The cold-to-warm machine perfusion of the liver
- Association between hospital interval and survival in patients with oral cancer: A waiting time paradox
- Translating a stress management intervention for rural Latina breast cancer survivors: The Nuevo Amanecer-II
- Comprehensive management of obstructive sleep apnea by telemedicine: Clinical improvement and cost-effectiveness of a Virtual Sleep Unit. A randomized controlled trial
- Proteomic characterisation of the Chlamydia abortus outer membrane complex (COMC) using combined rapid monolithic column liquid chromatography and fast MS/MS scanning
- Harnessing therapeutic viruses as a delivery vehicle for RNA-based therapy
- Korean soybean core collection: Genotypic and phenotypic diversity population structure and genome-wide association study
- Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study
- Measurement of structural integrity of the spinal cord in patients with amyotrophic lateral sclerosis using diffusion tensor magnetic resonance imaging
- Typological analysis of public-private partnerships in the veterinary domain
- Improved clinical outcome after medial open-wedge osteotomy despite cartilage lesions in the lateral compartment
- Rapid and structure-specific cellular uptake of selected steroids
- Avoiding gambling harm: An evidence-based set of safe gambling practices for consumers
- Epidemiology of chronic pain in Ukraine: Findings from the World Mental Health Survey
- PIAS1 is not suitable as a urothelial carcinoma biomarker protein and pharmacological target
- Double triage to identify poorly annotated genes in maize: The missing link in community curation
- N-acetyl cysteine restores the fertility of vitrified–warmed mouse oocytes derived through ultrasuperovulation
- Architecture of population-differentiated polymorphisms in the human genome
- Linguistic neutrosophic power Muirhead mean operators for safety evaluation of mines
- Extracellular vesicles nanoarray technology: Immobilization of individual extracellular vesicles on nanopatterned polyethylene glycol-lipid conjugate brushes
- Exercise intensity-dependent effects of arm and leg-cycling on cognitive performance
- How information about perpetrators’ nature and nurture influences assessments of their character, mental states, and deserved punishment
- Stringent response governs the oxidative stress resistance and virulence of Francisella tularensis
- In silico assessment of human Calprotectin subunits (S100A8/A9) in presence of sodium and calcium ions using Molecular Dynamics simulation approach
- Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging
- Measurable residual disease monitoring for patients with acute myeloid leukemia following hematopoietic cell transplantation using error corrected hybrid capture next generation sequencing
- Characteristics of complementary medicine therapists in Switzerland: A cross-sectional study
- Lack of generalization between explicit and implicit visuomotor learning
- Diet modulates cecum bacterial diversity and physiological phenotypes across the BXD mouse genetic reference population
- Effects of temperature and salinity on respiratory losses and the ratio of photosynthesis to respiration in representative Antarctic phytoplankton species
- Self-reported non-receipt of HIV test results: A silent barrier to HIV epidemic control in Mozambique
- Plasma midkine concentrations in healthy children, children with increased and decreased adiposity, and children with short stature
- Echocardiography overestimates LV mass in the elderly as compared to cardiac CT
- Efficacy of cotrimoxazole (Sulfamethoxazole-Trimethoprim) as a salvage therapy for the treatment of bone and joint infections (BJIs)
- Molecular mechanism of antimicrobial activity of chlorhexidine against carbapenem-resistant Acinetobacter baumannii
- First identification of the benzimidazole resistance-associated F200Y SNP in the beta-tubulin gene in Ascaris lumbricoides
- Green synthesis of silver nanoparticles using Solanum mammosum L. (Solanaceae) fruit extract and their larvicidal activity against Aedes aegypti L. (Diptera: Culicidae)
- Enterovirus 71 seroepidemiology in Taiwan in 2017 and comparison of those rates in 1997, 1999 and 2007
- Effect of statin on life prognosis in Japanese patients undergoing hemodialysis
- 13C and 15N NMR identification of product compound classes from aqueous and solid phase photodegradation of 2,4,6-trinitrotoluene
- Off-target effects of CRISPRa on interleukin-6 expression
- Exploring the antimicrobial properties of dark-operating ceramic-based nanocomposite materials for the disinfection of indoor air
- Experienced males recognise and avoid mating with non-virgin females in the western flower thrips
- Liver transplantation in patients with a history of migration—A German single center comparative analysis
- Retraction: The Different Role of Notch1 and Notch2 in Astrocytic Gliomas
- Correction: Understanding climate change from a global analysis of city analogues
- Comparison of 4D Flow MRI to 2D Flow MRI in the pulmonary arteries in healthy volunteers and patients with pulmonary hypertension
- The relationship between sleep quality, inappropriate medication use and frailty among older adults in aged care homes in Malaysia
- Clonal diversity and spatial genetic structure in the long-lived herb, Prairie trillium
- Medication histories documentation at the community pharmacy setting: A study from Jordan
- Population dynamics of an invasive bird parasite, Philornis downsi (Diptera: Muscidae), in the Galapagos Islands
- Because you had a bad day: General and daily relations between reactive temperament, emotion regulation, and depressive symptoms in youth
- Socioeconomic status and alcohol use disorders across the lifespan: A co-relative control study
- Generation of deletions and precise point mutations in Dictyostelium discoideum using the CRISPR nickase
- Polymorphisms in vasoactive eicosanoid genes of kidney donors affect biopsy scores and clinical outcomes in renal transplantation
- Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma: A preclinical F98 glioblastoma rat model study
- Validation and perception of a key feature problem examination in neurology
- Gender affirmative HIV care framework: Decisions on feminizing hormone therapy (FHT) and antiretroviral therapy (ART) among transgender women
- Quantifying international human mobility patterns using Facebook Network data
- Localization and characterization of thyroid microcalcifications: A histopathological study
- Young children are the main victims of fast food induced obesity in Brazil
- Understanding self-reported importance of religion/spirituality in a North American sample of individuals at risk for familial depression: A principal component analysis
- Standing balance of professional ballet dancers and non-dancers under different conditions
- 30-day unplanned readmission rate in otolaryngology patients: A population-based study in Thuringia, Germany
- Physical exercise stimulates salivary secretion of cystatins
- Vintage electronics for trusted radiation measurements and verified dismantlement of nuclear weapons
- Keepin’ it real: Linguistic models of authenticity judgments for artificially generated rap lyrics
- Carbon emission reduction and profit distribution mechanism of construction supply chain with fairness concern and cap-and-trade
- Modulations of microbehaviour by associative memory strength in Drosophila larvae
- Changes in peak expiratory flow rates using two head-tilt/chin-lift maneuver angles in young healthy conscious volunteers
- 3D image analysis reveals differences of CD30 positive cells and network formation in reactive and malignant human lymphoid tissue (classical Hodgkin Lymphoma)
- Change in larval fish assemblage in a USA east coast estuary estimated from twenty-six years of fixed weekly sampling
- 2-methylquinazoline derivative F7 as a potent and selective HDAC6 inhibitor protected against rhabdomyolysis-induced acute kidney injury
- Correction: Reducing growth and developmental problems in children: Development of an innovative postnatal risk assessment
- Comparative analysis of the vertebral pneumatization in pterosaurs (Reptilia: Pterosauria) and extant birds (Avialae: Neornithes)
- Associations between cognitive performance and sigma power during sleep in children with attention-deficit/hyperactivity disorder, healthy children, and healthy adults
- Retraction: MiR-375 Is Epigenetically Downregulated by HPV-16 E6 Mediated DNMT1 Upregulation and Modulates EMT of Cervical Cancer Cells by Suppressing lncRNA MALAT1
- Comparing growth patterns of three species: Similarities and differences
- Iron is increased in the brains of ageing mice lacking the neurofilament light gene
- Economic evaluation of community acquired pneumonia management strategies: A systematic review of literature
- A participatory community case study of periurban coastal flood vulnerability in southern Ecuador
- Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL
- Mitochondrial dysfunctions in leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL)
- MRI-based visualization of rTMS-induced cortical plasticity in the primary motor cortex
- Knowledge, attitudes, and practices related to anthrax and animal care: A case-control study in Georgia
- Information diffusion in signed networks
- Nurses’ perspectives on their communication with patients in busy oncology wards: A qualitative study
- Inflammation in acute coronary syndrome: Expression of TLR2 mRNA is increased in platelets of patients with ACS
- ART is key to clearing oncogenic HPV genotypes (HR-HPV) in anal mucosa of HIV-positive MSM
- Retraction: Fluid–Structure Interaction-Based Biomechanical Perception Model for Tactile Sensing
- Correction: Role of Caveolin-1 in Atrial Fibrillation as an Anti-Fibrotic Signaling Molecule in Human Atrial Fibroblasts
- The French adaptation and validation of the Partners in Health (PIH) scale among patients with chronic conditions seen in primary care
- Depth inversion with a 3D structure influences brightness perception
- Analysis of group evolution prediction in complex networks
- Effect of aridity and dune type on rhizosphere soil bacterial communities of Caragana microphylla in desert regions of northern China
- Knowledge, attitudes, and practices related to TB among the general population of Ethiopia: Findings from a national cross-sectional survey
- Correction: Personality traits in companion dogs—Results from the VIDOPET
- MANET 3.0: Hierarchy and modularity in evolving metabolic networks
- Agreement study on gait assessment using a video-assisted rating method in patients with idiopathic normal-pressure hydrocephalus
- Single fixed low-dose rituximab as induction therapy suppresses de novo donor-specific anti-HLA antibody production in ABO compatible living kidney transplant recipients
- Myomesin is part of an integrity pathway that responds to sarcomere damage and disease
- Acute normobaric hypoxia does not affect the simultaneous exercise-induced increase in circulating BDNF and GDNF in young healthy men: A feasibility study
- Systematic investigation on quad-metallic AgAuPdPt and tri-metallic AuPdPt NPs through the solid-state dewetting of quad-layer Ag/Au/Pd/Pt thin films on c-plane sapphire
- Video lecturing in Clicker-assisted English flipped class
- Significant changes of the choroid in patients with ocular ischemic syndrome and symptomatic carotid artery stenosis
- Skewed T cell responses to Epstein-Barr virus in long-term asymptomatic kidney transplant recipients
- Candidate genes expression profiling during wilting in chickpea caused by Fusarium oxysporum f. sp. ciceris race 5
- Host plants influence the composition of the gut bacteria in Henosepilachna vigintioctopunctata
- ‘We are all serving the same Ugandans’: A nationwide mixed-methods evaluation of private sector surgical capacity in Uganda
- The association between flavor capsule cigarette use and sociodemographic variables: Evidence from Chile
- Relations between gross motor skills and executive functions, controlling for the role of information processing and lapses of attention in 8-10 year old children
- Linalool acts as a fast and reversible anesthetic in Hydra
- Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka
- Using isotemporal substitution to predict the effects of changing physical behaviour on older adults’ cardio-metabolic profiles
- Adherence to general medical checkup and cancer screening guidelines according to self-reported smoking status: Korea National Health and Nutrition Examination Survey (KNHANES) 2010–2012
- Do older English adults exhibit day-to-day compensation in sedentary time and in prolonged sedentary bouts? An EPIC-Norfolk cohort analysis
- Linoleic acid supplementation of cell culture media influences the phospholipid and lipid profiles of human reconstructed adipose tissue
- Correction: Factors associated with hospitalization and death among TB/HIV co-infected persons in Porto Alegre, Brazil
- An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
- Reporting adverse events related to medical devices: A single center experience from a tertiary academic hospital
- Enterohemorrhagic Escherichia coli infection inhibits colonic thiamin pyrophosphate uptake via transcriptional mechanism
- Estimating biodiversity changes in the Camargue wetlands: An expert knowledge approach
- Decreased risk of Parkinson’s disease in diabetic patients with thiazolidinediones therapy: An exploratory meta-analysis
- Retraction: Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis
- Lipoarabinomannan from Mycobacterium indicus pranii shows immunostimulatory activity and induces autophagy in macrophages
- A measure of inconsistencies in intertemporal choice
- A novel radiopaque tissue marker for soft tissue localization and in vivo length and area measurements
- Anatomical, histological and computed tomography comparisons of the eye and adnexa of crab-eating fox (Cerdocyon thous) to domestic dogs
- Subpopulation augmentation among habitat patches as a tool to manage an endangered Mojave Desert wetlands-dependent rodent during anthropogenic restricted water climate regimes
- Characteristics of CD5-positive diffuse large B-cell lymphoma among Koreans: High incidence of BCL2 and MYC double-expressors
- Fossil tabulate corals reveal outcrops of Paleozoic sandstones in the Atlantic Coastal Plain Province, Southeastern USA
- Coming and going – Historical distributions of the European oyster Ostrea edulis Linnaeus, 1758 and the introduced slipper limpet Crepidula fornicata Linnaeus, 1758 in the North Sea
- Behavioral predictors of subsequent respiratory illness signs in dogs admitted to an animal shelter
- Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation
- Can emotional intelligence be improved? A randomized experimental study of a business-oriented EI training program for senior managers
- Genetic variability in landraces populations and the risk to lose genetic variation. The example of landrace ‘Kyperounda’ and its implications for ex situ conservation
- Sleep problems are a strong predictor of stress-related metabolic changes in police officers. A prospective study
- Age, sex and primary care setting differences in patients’ perception of community healthcare seeking behaviour towards health services
- Kinematic analyses including finite helical axes of drop jump landings demonstrate decreased knee control long after anterior cruciate ligament injury
- Effects of model inaccuracies on reaching movements with intermittent control
- C-reactive protein to albumin ratio predicts the outcome in renal cell carcinoma: A meta-analysis
- A new synthetic lure for management of the invasive giant African snail, Lissachatina fulica
- Bridging solvent molecules mediate RNase A – Ligand binding
- Variation in methods, results and reporting in electronic health record-based studies evaluating routine care in gout: A systematic review
- The use of prophylactic intra-aortic balloon pump in high-risk patients undergoing coronary artery bypass grafting
- Compliance with clinical guidelines for breast cancer management: A population-based study of quality-of-care indicators in France
- Dysregulated T helper type 1 (Th1) and Th17 responses in elderly hospitalised patients with infection and sepsis
- Acute effects of differential learning on football kicking performance and in countermovement jump
- Escherichia coli and Salmonella spp. isolated from Australian meat chickens remain susceptible to critically important antimicrobial agents
- Play like me: Similarity in playfulness promotes social play
- Awareness of family health history in a predominantly young adult population
- Care pathways during a child’s final illness in rural South Africa: Findings from a social autopsy study
- Intranasal lidocaine for acute migraine: A meta-analysis of randomized controlled trials
- Evaluating case management as a complex intervention: Lessons for the future
- Allele-specific enhancer interaction at the Peg3 imprinted domain
- Has the “M” word been framed? Marijuana, cannabis, and public opinion
- Is spontaneous normalization of systolic blood pressure within 24 hours after ischemic stroke onset related with favorable outcomes?
- Mixotrophic cultivation of Spirulina platensis in dairy wastewater: Effects on the production of biomass, biochemical composition and antioxidant capacity
- Constitutive expression of an A-5 subgroup member in the DREB transcription factor subfamily from Ammopiptanthus mongolicus enhanced abiotic stress tolerance and anthocyanin accumulation in transgenic Arabidopsis
- Stable carbon isotope diagnostics of mammalian metabolism, a high-resolution isotomics approach using amino acid carboxyl groups
- Factors associated with depressive symptoms in patients with ankylosing spondylitis in Northern Taiwan
- A multicenter prospective study of 515 febrile neutropenia episodes in Argentina during a 5-year period
- Retraction: Reversal Effect of ST6GAL 1 on Multidrug Resistance in Human Leukemia by Regulating the PI3K/Akt Pathway and the Expression of P-gp and MRP1
- Potential role for microRNA-16 (miR-16) and microRNA-93 (miR-93) in diagnosis and prediction of disease progression in mycosis fungoides in Egyptian patients
- Rapid visual categorization is not guided by early salience-based selection
- Relative contribution of climate and non-climate drivers in determining dynamic rates of boreal birds at the edge of their range
- A simple-to-use nomogram to predict long term survival of patients undergoing coronary artery bypass grafting (CABG) using bilateral internal thoracic artery grafting technique
- Effects of sonication parameters on transcranial focused ultrasound brain stimulation in an ovine model
- Antenatal and intrapartum interventions for reducing caesarean section, promoting vaginal birth, and reducing fear of childbirth: An overview of systematic reviews
- Relative species abundance successfully predicts nestedness and interaction frequency of monthly pollination networks in an alpine meadow
- Correction: RCER: Reliable Cluster-based Energy-aware Routing protocol for heterogeneous Wireless Sensor Networks
- Amphibians on the hotspot: Molecular biology and conservation in the South American Atlantic Rainforest
- Role of psychosocial status in predicting health-related quality of life at 1-year follow-up among newly diagnosed people living with HIV
- Application of national pollutant inventories for monitoring trends on dioxin emissions from stationary industrial sources in Australia, Canada and European Union
- The association between vaccination confidence, vaccination behavior, and willingness to recommend vaccines among Finnish healthcare workers
- Retraction: Interleukin-1β-Induced Autophagy-Related Gene 5 Regulates Proliferation of Embryonic Stem Cell-Derived Odontoblastic Cells
- A localized sanitation status index as a proxy for fecal contamination in urban Maputo, Mozambique
- E2 protein is the major determinant of specificity at the human papillomavirus origin of replication
- “You’re kind of at war with yourself as a nurse”: Perspectives of inpatient nurses on treating people who present with a comorbid opioid use disorder
- A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury
- Circulating cell-free DNA from plasma undergoes less fragmentation during bisulfite treatment than genomic DNA due to low molecular weight
- Understanding fatigue in adults with visual impairment: A path analysis study of sociodemographic, psychological and health-related factors
- Retraction: Mouse-Induced Pluripotent Stem Cells Differentiate into Odontoblast-Like Cells with Induction of Altered Adhesive and Migratory Phenotype of Integrin
- A novel analytical method to assess the effect of imipenem/cilastatin on liver function laboratory indexes in Chinese underage inpatients: Probability distribution curve
- The cause of anorexia and proportion of its recovery in older adults without underlying disease: Results of a retrospective study
- Referral and admission to intensive care: A qualitative study of doctors’ practices in a Tanzanian university hospital
- Agreement between clinical and non-clinical digital manometer for assessing maximal respiratory pressures in healthy subjects
- Heads or tails? Differential translational regulation in cercarial heads and tails of schistosome worms
- Horizontal seed dispersal by dung beetles reduced seed and seedling clumping, but did not increase short-term seedling establishment
- The coupling of the M2 muscarinic receptor to its G protein is voltage dependent
- Subsidy strategy of pharmaceutical e-commerce platform based on two-sided market theory
- Shoulder girdle injuries involving the medial clavicle differ from lateral clavicle injuries with a focus on concomitant injuries and management strategies: A retrospective study based on nationwide routine data
- Unraveling middle childhood attachment-related behavior sequences using a micro-coding approach
- Divergence history and hydrothermal vent adaptation of decapod crustaceans: A mitogenomic perspective
- Duration of solid fuel cookstove use is associated with increased risk of acute lower respiratory infection among children under six months in rural central India
- Evolving flocking in embodied agents based on local and global application of Reynolds’ rules
- Non-invasive contrast enhanced ultrasound molecular imaging of inflammation in autoimmune myocarditis for prediction of left ventricular fibrosis and remodeling
- Care coordination for chronic and complex health conditions: An experienced based co-design study engaging consumer and clinician groups for service improvement
- Association between socioeconomic status and diet quality in Mexican men and women: A cross-sectional study
- Surveillance of panicle positions by unmanned aerial vehicle to reveal morphological features of rice
- Is Betula carpatica genetically distinctive? A morphometric, cytometric and molecular study of birches in the Bohemian Massif with a focus on Carpathian birch
- Correction: Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance
- The genome of the migratory nematode, Radopholus similis, reveals signatures of close association to the sedentary cyst nematodes
- Factors associated with pneumococcal carriage and density in infants and young children in Laos PDR
- Overlap between telangiectasia and photoreceptor loss increases with progression of macular telangiectasia type 2
- The role of hope for health professionals in rehabilitation: A qualitative study on unfavorable prognosis communication
- Expression of miR-34a-5p is up-regulated in human colorectal cancer and correlates with survival and clock gene PER2 expression
- Molecular characterization and In Vitro synthesis of infectious RNA of a Turnip vein-clearing virus isolated from Alliaria petiolata in Hungary
- Assessment of client satisfaction with pharmacist services at outpatient pharmacy of Tikur Anbessa Specialized Hospital
- Thermogravimetric analysis of the co-combustion of coal and polyvinyl chloride
- Roles of leptin in the recovery of muscle and bone by reloading after mechanical unloading in high fat diet-fed obese mice
- Unexpected high seroprevalence of hepatitis E virus in patients with alcohol-related cirrhosis
- APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy
- Integrating a gait analysis test in hospital rehabilitation: A service design approach
- Correction: Bioactivity-guided isolation of rosmarinic acid as the principle bioactive compound from the butanol extract of Isodon rugosus against the pea aphid, Acyrthosiphon pisum
- Soil-borne fungi influence seed germination and mortality, with implications for coexistence of desert winter annual plants
- Applying Corrigan’s progressive model of self-stigma to people with depression
- Do psychosocial factors modify the negative association between disability and life satisfaction in old age?
- Public perception of coastal habitat loss and habitat creation using artificial floating islands in the UK
- Transcriptional foliar profile of the C3-CAM bromeliad Guzmania monostachia
- Application of tuned liquid column ball damper (TLCBD) for improved vibration control performance of multi-storey structure
- Do protection gradients explain patterns in herbivore densities? An example with ungulates in Zambia’s Luangwa Valley
- Consequences of chronic bacterial infection in Drosophila melanogaster
- The effects of environmental parameters on the microbial activity in peat-bog lakes
- Differences in protein structural regions that impact functional specificity in GT2 family β-glucan synthases
- Correction: Identification of lysine methylation in the core GTPase domain by GoMADScan
- Changes of absorbed dose rate in air in metropolitan Tokyo relating to radiocesium released from the Fukushima Daiichi Nuclear Power Plant accident: Results of a five-year study
- Histological chorioamnionitis, antenatal steroids, and neonatal outcomes in very low birth weight infants: A nationwide study
- A machine learning approach for the prediction of pulmonary hypertension
- Altered microbiota, fecal lactate, and fecal bile acids in dogs with gastrointestinal disease
- Impaired processing of threat in psychopathy: A systematic review and meta-analysis of factorial data in male offender populations
- Dimethyl disulfide (DMDS) as an effective soil fumigant against nematodes in China
- Risk factors for hepatitis C infection among adult patients in Kedah state, Malaysia: A case–control study
- Factoring a 2 x 2 contingency table
- The development of connectives in three to five-year-old monolingual Spanish-speaking children
- Foliar plasticity related to gradients of heat and drought stress across crown orientations in three Mediterranean Quercus species
- The evolution of haploid chromosome numbers in Meliponini
- Bloodstream infections caused by Escherichia coli in onco-haematological patients: Risk factors and mortality in an Italian prospective survey
- Facial features and unethical behavior – Doped athletes show higher facial width-to-height ratios than non-doping sanctioned athletes
- Non-resolution of non-alcoholic fatty liver disease (NAFLD) among urban, adult Sri Lankans in the general population: A prospective, cohort follow-up study
- Left ventricular simulation of cardiac compression: Hemodynamics and regional mechanics
- Are we ready for scaling up restoration actions? An insight from Mediterranean macroalgal canopies
- Age-related changes in size, bone microarchitecture and volumetric bone mineral density of the mandible in the harbor seal (Phoca vitulina)
- Parasitism modifies the direct effects of warming on a hemiparasite and its host
- Analytic performance of PANArray HPV and HPV 9G DNA chip tests for genotyping of high-risk human papillomavirus in cervical ThinPrep PreservCyt samples
- Transcript profile of skeletal muscle lipid metabolism genes affected by diet in a piglet model of low birth weight
- Differential impact of smoking on cardiac or non-cardiac death according to age
- Influence of injectate volume on paravertebral spread in erector spinae plane block: An endoscopic and anatomical evaluation
- Correction: Nitrogen starvation induces distinct photosynthetic responses and recovery dynamics in diatoms and prasinophytes
- Healthcare needs and programmatic gaps in transition from pediatric to adult care of vertically transmitted HIV infected adolescents in India
- Retraction: Neuronal Differentiation Dictates Estrogen-Dependent Survival and ERK1/2 Kinetic by Means of Caveolin-1
- Correction: Disability and its association with sociodemographic factors among elderly persons residing in an urban resettlement colony, New Delhi, India
- Antibacterial activity of varying UMF-graded Manuka honeys
- Correction: Synthesis of IL-6 by Hepatocytes Is a Normal Response to Common Hepatic Stimuli
- Detection and genetic characterization of Echinococcus granulosus mitochondrial DNA in serum and formalin-fixed paraffin embedded cyst tissue samples of cystic echinococcosis patients
- Deep-learning-based risk stratification for mortality of patients with acute myocardial infarction
- Links between meaning in life and physical quality of life after rehabilitation: Mediating effects of positive experiences with physical exercises and mobility
- The estrogen effect; clinical and histopathological evidence of dichotomous influences in dogs with spontaneous mammary carcinomas
- The association between socioeconomic status, psychopathological symptom burden in mothers, and early childhood caries of their children
- Increased rate of FEV1 decline in HIV patients despite effective treatment with HAART
- Parallels between stream and coastal water quality associated with groundwater discharge
- Determinants of anemia among pregnant women attending antenatal care in Horo Guduru Wollega Zone, West Ethiopia: Unmatched case-control study
- Depression and anxiety among pregnant women living with HIV in Kilimanjaro region, Tanzania
- Shift in trophic niches of soil microarthropods with conversion of tropical rainforest into plantations as indicated by stable isotopes (15N, 13C)
- On the development of sleep states in the first weeks of life
- CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro
- Investigation into pathophysiology of naturally occurring palatal instability and intermittent dorsal displacement of the soft palate (DDSP) in racehorses: Thyro-hyoid muscles fatigue during exercise
- Correction: Reducing phenolic off-flavors through CRISPR-based gene editing of the FDC1 gene in Saccharomyces cerevisiae x Saccharomyces eubayanus hybrid lager beer yeasts
- MitoToxy assay: A novel cell-based method for the assessment of metabolic toxicity in a multiwell plate format using a lactate FRET nanosensor, Laconic
- Correction: Evidence for plant-derived xenomiRs based on a large-scale analysis of public small RNA sequencing data from human samples
- Correction: Prognostic impact of systolic blood pressure variability in people with diabetes
- Retraction: Sialoglycosylation of RBC in Visceral Leishmaniasis Leads to Enhanced Oxidative Stress, Calpain-Induced Fragmentation of Spectrin and Hemolysis
- Too much? Mortality and health service utilisation among Danish children 1999-2016: A register-based study
- Effects of sodium-glucose cotransporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors on diabetic retinopathy and its progression: A real-world Korean study
- Shipworm bioerosion of lithic substrates in a freshwater setting, Abatan River, Philippines: Ichnologic, paleoenvironmental and biogeomorphical implications
- Genetic codes optimized as a traveling salesman problem
- Effect of antenatal detection of small-for-gestational-age newborns in a risk stratified retrospective cohort
- Using family network data in child protection services
- Transcriptome sequencing reveals the effect of biochar improvement on the development of tobacco plants before and after topping
- Volatile anesthetics versus total intravenous anesthesia in patients undergoing coronary artery bypass grafting: An updated meta-analysis and trial sequential analysis of randomized controlled trials
- Cumulative fluid balance predicts mortality and increases time on mechanical ventilation in ARDS patients: An observational cohort study
- Stated-preference research in HIV: A scoping review
- Correction: Survival of infants ≤24 months of age with brain tumors: A population-based study using the SEER database
- Antinociceptive compounds and LC-DAD-ESIMSn profile from Dictyoloma vandellianum leaves
- Time series experimental design under one-shot sampling: The importance of condition diversity
- Evaluation of protocols for rRNA depletion-based RNA sequencing of nanogram inputs of mammalian total RNA
- Prevalence and predictors of primary postpartum hemorrhage: An implication for designing effective intervention at selected hospitals, Southern Ethiopia
- Correction: Stillbirths in urban Guinea-Bissau: A hospital- and community-based study
- Correction: Method for spike detection from microelectrode array recordings contaminated by artifacts of simultaneous two-photon imaging
- Correction: Peripheral blood mononuclear cells extracts VEGF protein levels and VEGF mRNA: Associations with inflammatory molecules in a healthy population
- Correction: Novel site-specific PEGylated L-asparaginase
- Effect of caffeine ingestion on competitive rifle shooting performance
- Correction: Color adaptation induced from linguistic description of color
- MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity
- Correction: A biface production older than 600 ka ago at Notarchirico (Southern Italy) contribution to understanding early Acheulean cognition and skills in Europe
- Correction: A urinary extracellular vesicle microRNA biomarker discovery pipeline; from automated extracellular vesicle enrichment by acoustic trapping to microRNA sequencing
- Measurement of horizontal ocular deviation on magnetic resonance imaging in various disease with acute vertigo
- Clinical outcomes of early gastric cancer with non-curative resection after pathological evaluation based on the expanded criteria
- Detection of quantitative trait loci associated with drought tolerance in St. Augustinegrass
- An examination of the Kuleshov effect using still photographs
- Correction: Relationship between non-communicable diseases and background characteristics among homeless people in Nagoya City, Japan
- An exploration of automated narrative analysis via machine learning
- Correction: Frozen by stress: Stress increases scope insensitivity
- The pragmatic role of trust in young children’s interpretation of unfamiliar signals
- Measuring egocentric distance perception in virtual reality: Influence of methodologies, locomotion and translation gains
- Mathematical modeling of cardiac function to evaluate clinical cases in adults and children
- Correction: Forecasting the impact of population ageing on tuberculosis incidence
- “The car is my extra legs” – Experiences of outdoor mobility amongst immigrants in Sweden with late effects of polio
- Correction: Multilevel analyses of on-demand medication data, with an application to the treatment of Female Sexual Interest/Arousal Disorder
- Correction: The world’s user-generated road map is more than 80% complete
- Correction: Predictors of opioid efficacy in patients with chronic pain: A prospective multicenter observational cohort study
- Correction: Comparative prognostic accuracy of sepsis scores for hospital mortality in adults with suspected infection in non-ICU and ICU at an academic public hospital
- Correction: Biosynthesis of the oxygenated diterpene nezukol in the medicinal plant Isodon rubescens is catalyzed by a pair of diterpene synthases
- Correction: Effect of early measles vaccine on pneumococcal colonization: A randomized trial from Guinea-Bissau
- Correction: Tuberculosis patients in an Indian mega-city: Where do they live and where are they diagnosed?
- Correction: Priority Queue Based Reactive Buffer Management Policy for Delay Tolerant Network under City Based Environments
- Correction: Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma
- Correction: A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas
- Correction: Evolution and study of a copycat effect in intimate partner homicides: A lesson from Spanish femicides
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- Correction: Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression
- Correction: Factors influencing the behaviour and perceptions of Australian veterinarians towards antibiotic use and antimicrobial resistance
- Correction: Nonalcoholic fatty liver disease is a risk factor for large-for-gestational-age birthweight
- Retraction: Butyrate Attenuates Lipopolysaccharide-Induced Inflammation in Intestinal Cells and Crohn's Mucosa through Modulation of Antioxidant Defense Machinery
- Retraction: Tetrandrine Suppresses Lipopolysaccharide-Induced Microglial Activation by Inhibiting NF-κB and ERK Signaling Pathways in BV2 Cells
- Correction: Isolation of five Enterobacteriaceae species harbouring blaNDM-1 and mcr-1 plasmids from a single paediatric patient
- Correction: Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents
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