Temporal weights in loudness: Investigation of the effects of background noise and sound level
Authors:
Alexander Fischenich aff001; Jan Hots aff002; Jesko Verhey aff002; Daniel Oberfeld aff001
Authors place of work:
Department of Psychology, Johannes Gutenberg-Universität Mainz, Mainz, Germany
aff001; Department of Experimental Audiology, Otto von Guericke University Magdeburg, Magdeburg, Germany
aff002
Published in the journal:
PLoS ONE 14(11)
Category:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0223075
Summary
Previous research has consistently shown that for sounds varying in intensity over time, the beginning of the sound is of higher importance for the perception of loudness than later parts (primacy effect). However, in all previous studies, the target sounds were presented in quiet, and at a fixed average sound level. In the present study, temporal loudness weights for a time-varying narrowband noise were investigated in the presence of a continuous bandpass-filtered background noise and the average sound levels of the target stimuli were varied across a range of 60 dB. Pronounced primacy effects were observed in all conditions and there were no significant differences between the temporal weights observed in the conditions in quiet and in background noise. Within the conditions in background noise, there was a significant effect of the sound level on the pattern of weights, which was mainly caused by a slight trend for increased weights at the end of the sounds (“recency effect”) in the condition with lower average level. No such effect was observed for the in-quiet conditions. Taken together, the observed primacy effect is largely independent of masking as well as of sound level. Compatible with this conclusion, the observed primacy effects in quiet and in background noise can be well described by an exponential decay function using parameters based on previous studies. Simulations using a model for the partial loudness of time-varying sounds in background noise showed that the model does not predict the observed temporal loudness weights.
Keywords:
Neurons – Sensory perception – Vision – Sound pressure – Background signal noise – Ambient noise – Auditory nerves
Introduction
Loudness is one of the fundamental aspects of auditory sensation and is important when it comes to the perception of our environment through the auditory channel. Extensive research on steady-state sounds has been done in the past and loudness models are available that account for a large proportion of the psychoacoustic data [1–4]. However, static loudness models do not seem to account for all aspects of the loudness of sounds that vary in level across time [5,6].
One reason may be that not all temporal parts of a sound are weighted equally when listeners judge loudness. Previous studies consistently show that the beginning of a time-varying sound is of higher importance for the perception of loudness than later temporal parts [7–9], which has been referred to as a primacy effect (for a review see [10]). The primacy effect can be described by an exponential decay function with a time-constant of about 200–300 ms [10,11]. The temporal weight at the beginning of the sound is 4 to 5 times higher than the asymptotic weight, and the weight assigned to a temporal portion of a sound is the integral of this function over the segment duration [11]. In addition to the primacy effect, some studies also found higher perceptual weights assigned to the end of the sounds, commonly referred to as a recency effect [8,9].
Oberfeld and Plank [7] suggested several potential explanations of the primacy effect. First, the primacy effect might originate from an attention orientation response [12–14] to the sound onset, in the sense that the sound onset captures the attention [15]. However, their data did not support this explanation. They presented sounds starting with a gradual increase in level across the first few hundred milliseconds ("fade-in"). This should have reduced the perceived abruptness of the onset and, as a consequence, the capture of attention [16,17]. However, the data in [7] showed a delayed primacy effect in the sense of a high weight on the first unattenuated temporal segment. Another possible source of the primacy effect might be the response characteristic of auditory nerve (AN) neurons which tend to show a peak in the firing rate at the onset of a sound [18–21]. However, because the activity of the auditory pathway involves different types of neurons and efferent as well as afferent loops, a precise model of the auditory nerve would be required to evaluate to which extent the observed primacy effect can be explained on this basis.
Here, we investigate two factors that could potentially have an effect on both an attention orienting response and on the response of auditory nerve neurons. The first factor is the presence or absence of a continuous background noise, and the second factor is the level of the target sound.
Concerning the first factor, all previous experiments measuring temporal loudness weights presented sounds in quiet. This is a rather artificial condition since in a real environment, a target sound (we are listening to) is usually embedded in a background made of other sounds. The aim of the present study was thus to investigate the influence of a continuous background noise on the occurrence of the primacy and recency effects. The target sounds were presented in quiet as well as in a background noise. The presence of the continuous background noise could be expected to reduce the capture of attention by the target sound onset, because it makes the onset of this sound less abrupt or less surprising. Although we are not aware of relevant studies using auditory distractors, in the visual domain attentional capture appears to occur only for abrupt onsets of visual distractors [16,17]. Therefore, if the primacy effect was due to attentional capture to the target sound onset, it should be reduced for sounds that are presented in continuous background noise. In addition, responses of auditory nerve neurons are sensitive to background stimuli in the way that in the presence of a background noise the initial peak becomes smaller compared to the steady-state rate [22]. Thus, if the primacy effect was related to the initial peak in the AN firing rate, we assume that its size should be reduced in the presence of a background noise.
Concerning the second factor (target level), several studies investigated the effect of the relative level of temporal target components within a sound on the perceptual weights, showing that target components with a higher relative level receive a higher weight ("loudness dominance"; e.g., [7,23]). However, no previous study systematically tested for an effect of the average target level on the temporal loudness weights. Therefore, in the present study we measured temporal loudness weights for several different average sound pressure levels of the target sounds. A variation of the average target level might again affect the capture of attention to the sound onset, in the sense that the onset of a target sound presented only a few decibels above the detection threshold might appear less abrupt than the onset of a target sound with much higher level [16,17]. This leads to the prediction that if the primacy effect is related to attentional capture, more pronounced primacy effects should be found in the conditions with a higher target level, compared to target sounds presented just above the detection threshold. However, we are not aware of studies investigating the effect of the intensity of auditory or visual distractors on attentional capture.
In addition, the sound level has an effect on the responses of auditory nerve neurons, which show an increase in the initial peak of the firing rate relative to the steady-state response with increasing sound level [18,20]. Therefore, if the primacy effect was due to the initial peak in the firing rate of auditory nerve neurons, we hypothesize that it should be more pronounced at higher target sound levels.
To investigate the influence of both target level and background noise simultaneously, some of the experimental conditions presented the same average target sound pressure level in quiet and in background noise. In addition, a condition in quiet was compared to a condition in background noise at the same level above threshold, i.e., the same sensation level. This made it possible to test whether or not the primacy effect depends on the level or the signal-to-noise-ratio, which was not investigated before.
Method
Listeners
Eight normal-hearing listeners (7 female, 1 male, age 18–26 years) participated in this study. The experiment was conducted according to the principles expressed in the Declaration of Helsinki. All listeners participated voluntarily and provided informed written consent, after the topic of the study and potential risks had been explained to them. They were uninformed about the experimental hypotheses. The Ethics Committee of the Institute of Psychology of the Johannes Gutenberg-Universität Mainz approved the study (reference number 2016-JGU-psychEK-002). Hearing thresholds were measured by Békésy audiometry with pulsed 270-ms pure tones. All participants showed thresholds lower than or equal to 15 dB HL in the frequency range between 125 Hz and 8 kHz in both ears. All participants were students from Johannes Gutenberg-Universität Mainz and received partial course credit for their participation.
Stimuli and apparatus
The stimuli were level-fluctuating noises consisting of ten bandpass-filtered low-noise noise segments. Bandpass-filtered noise was generated by transforming a broadband Gaussian noise into the frequency domain via a Fast Fourier Transform (FFT), setting the frequency components to zero outside the desired passband, and transforming it back to the time domain via an inverse FFT. The lower and upper cutoff frequencies were 770 Hz (7 Bark) and 1270 Hz (9 Bark), respectively. To reduce the intrinsic level fluctuations of the noise, the stimulus was multiplied by the inverse of its Hilbert envelope and then again bandlimited in the frequency domain, as described above. This multiplication and bandlimiting was repeated once. The resulting noise is commonly referred to as low-noise noise (LNN). This procedure to generate LNN is the second method proposed in Kohlrausch et al. [24]. Each noise segment had a duration of 120 ms including 20-ms cos2 on - and off-ramps. The segments were presented with a temporal overlap of 20 ms, resulting in a total stimulus duration of 1020 ms. Level fluctuations were created by drawing each segment’s sound pressure level independently and at random from a normal distribution on each trial.
In some conditions, the stimuli were presented in continuous background noise. The background noise was a Gaussian bandpass noise that was filtered with a 3rd-order Butterworth filter with cutoff frequencies of 300 Hz (3 Bark) and 2320 Hz (13 Bark), presented diotically with a sound pressure level of 50 dB SPL.
All sounds were generated digitally with a sampling frequency of 44.1 kHz, D/A-converted by an RME ADI/S with 24 bit resolution, attenuated by a TDT PA5 programmable attenuator, buffered by a TDT HB7 headphone buffer, and presented diotically via Sennheiser HDA 200 circumaural headphones. The reproducing system was calibrated according to IEC 60318–1 : 1998 [25] and free-field equalized as specified in ISO 389–8 [26]. Participants were tested in a double-walled sound-insulated chamber. Instructions were presented on a computer screen.
Procedure
Measurement of detection thresholds
In order to ensure the same audibility of the target sounds in the loudness judgment task, for each participant, the individual detection thresholds for a single 120-ms LNN-segment (including 20-ms on - and off ramps) were determined in quiet and in the presence of the continuous background noise. Thresholds were measured using an adaptive two-interval, two-alternative forced-choice task [27]. On each trial, there were two observation intervals. In one of the two observation intervals (selected randomly), the signal (120-ms LNN-segment) was presented. The other interval contained no signal. Listeners selected the interval containing the signal. The initial signal level was 45 dB SPL in the condition in background noise and 20 dB SPL in the in-quiet condition. The level of the signal was adjusted by a three-down, one-up adaptive rule. The step size was 8 dB until the third reversal, and 2 dB for the remaining six reversals. The arithmetic mean of the signal levels at the final six reversals was taken as the detection threshold, corresponding to 79.4% correct. For each listener, a minimum of three adaptive blocks was presented for each of the two conditions (in quiet and in background noise). A block was discarded if the standard deviation of the signal levels at the six final reversals was greater than 6 dB. In the following, the average detection threshold in quiet is denoted Lth_quiet, and the detection threshold in background noise is denoted Lth_BGN. Resulting thresholds for the eight listeners are shown in Table 1. Across the eight listeners, the mean threshold in quiet was 3.6 dB SPL (SD = 5.9 dB, min = −3.6 dB SPL, max = 13.4 dB SPL), and under masking 43.2 dB SPL (SD = 3.1 dB, min = 40.2 dB SPL, max = 50.0 dB SPL).
Measurement of temporal loudness weights
To estimate temporal loudness weights, we used an established experimental paradigm from previous experiments (e.g., [7,10,11]). The target stimuli were level-fluctuating narrowband noises consisting of ten contiguous temporal segments. On each trial, the ten segment levels were selected by drawing each segment’s sound pressure level independently and at random from a normal distribution.
Temporal weights were measured for two mean segment levels in conditions with continuous background noise (termed BGN in the following), and for three mean segment levels in conditions without background noise (in quiet). In the first condition in background noise, the mean of the normal distribution from which the segment levels were drawn was 7.5 dB higher than the individual detection threshold for a single temporal segment in the continuous background noise (see previous subsection on the measurement of detection thresholds), LSLBGN7.5 = Lth_BGN + 7.5 dB. Thus, on average, the signal had a sensation level (SL) of 7.5 dB SL under masking, and this condition is referred to as BGNSLBGN7.5. In the second condition in background noise, the mean of the normal distribution was 30 dB higher than the individual detection threshold in the background noise, LSLBGN30 = Lth_BGN + 30 dB. This condition is referred to as BGNSLBGN30. Two in-quiet conditions (i.e., without background noise) with the same mean sound pressure level of the segments as in the two conditions in background noise were presented: QuietSLBGN7.5 used the same mean segment level as BGNSLBGN7.5, and the mean segment level in QuietSLBGN30 was the same as in BGNSLBGN30. In addition, an in-quiet condition with the mean segment level set to 7.5 dB SL (that is, 7.5 dB above the individual detection threshold for a single segment in quiet), LSLquiet7.5 = Lth_quiet + 7.5 dB, referred to as QuietSLquiet7.5, was included in the experiment. Table 2 provides an overview of the five experimental conditions and the corresponding target levels. Table 1 shows the three different resulting mean target sound pressure levels for the eight listeners.
Fig 1 shows an example of the individual thresholds and mean target levels for a listener with a threshold in quiet of Lth_quiet = 2.3 dB SPL and a threshold in background noise of Lth_BGN = 41.9 dB SPL. The figure illustrates that we varied both the absolute sound pressure level of the target sounds and the level of the target sounds relative to the individual detection thresholds.
The standard deviation of each of the level distributions was σ = 2.5 dB. Unacceptably loud or soft segments were avoided by limiting the range of possible sound pressure levels to three standard deviations below and above the mean of the distribution.
For each condition, a distribution with higher mean and a distribution with lower mean were created by adding or subtracting a value of ΔL/2 to the individual mean segment level in the corresponding condition, respectively. On each trial, there was a 0.5 probability of presenting a sound with segment levels drawn from the distribution with the higher or lower mean. For conditions BGNSLBGN30, QuietSLBGN 7.5, and QuietSLBGN30, ΔL was 2.0 dB, while for BGNSLBGN7.5 and QuietSLquiet7.5, ΔL was 2.5 dB. These values were selected on the basis of pilot data in order to maintain a performance level of about 70% correct. Please note that the choice of a minimum SL of 7.5 dB in quiet as well as in background noise ensured that, despite the random level fluctuations, all segment levels were at or above the individual thresholds in virtually all of the trials. Fig 2 shows a fluctuating level profile of a sound drawn from the distribution with the lower mean in condition BGNSLBGN7.5.
After each trial, listeners decided whether the presented target sound had been "louder" or "softer". They were instructed to use previous trials within an experimental block as a reference for their loudness judgments. The inter-trial interval was 1500 ms, with the restriction that the next trial never started before the response to the preceding trial had been given. Trial-by-trial feedback was provided during the first seven trials of each block so that the participants could easily adopt a decision criterion for the new experimental condition. Those trials were not considered for the data analysis. A response was classified as correct if the response (“softer”/”louder”) matched the mean of the distribution that the stimulus’ segment levels were drawn from. A summarizing feedback was provided each time 50 trials were completed. It contained the number of correct and false answers, percent correct, the number of trials from the distribution with higher mean and the distribution with lower mean, and the number of “louder” and “softer” responses.
The usual rule of thumb from previous experiments [10] was used concerning the number of trials necessary to obtain reliable weight estimates, and 100 trials per temporal segment were presented. Since the sounds in each condition contained ten temporal segments, 1000 trials were presented per condition, resulting in a total of 5000 trials per listener.
Sessions
Each listener participated in five experimental sessions, each containing 1000 trials of the loudness judgment task (200 per condition). Additionally, there was an initial session in which audiometric thresholds and detection thresholds in quiet and under masking were measured, and practice blocks of the loudness judgment task were presented for all of the five conditions. The practice blocks were excluded from data analysis. Within each session, sounds of the same condition were arranged into blocks of 200 trials. The order of conditions was chosen randomly. The duration of each session was approximately 60 minutes, including a mandatory pause of about 5 minutes.
Data analysis
The perceptual weights representing the importance of the 10 temporal segments for the decision in the loudness judgment task were estimated from the trial-by-trial data via multiple logistic regression. The decision model assumed that the listener compares a weighted sum of the segment levels to a fixed decision criterion, and responds that the sound was of the "louder" type if the weighted sum exceeds the criterion (a detailed description of the decision model is provided by [7]). If the weighted sum is smaller than the criterion, it is assumed that the listener classifies the sound as "softer". In the data analysis, the binary responses ("louder" or "softer" type of sound) served as the dependent variable. The predictors (i.e., the ten segment levels) were entered simultaneously. The regression coefficients were taken as the decision weight estimates.
A separate logistic regression model was fitted for each combination of listener and condition. Since the relative contributions of the different temporal segments to the decision were of interest rather than the absolute magnitude of the regression coefficients, the ten regression coefficients were normalized for each fitted model such that the mean of their absolute values was 1.0. This resulted in a set of relative perceptual weights for each combination of listener and condition. We also fitted separate logistic regression models to trials in the first and last experimental session (session 2 & session 6), again for each combination of listener and condition separately, to investigate whether the temporal weighting changed during the course of the experiment.
A summary measure of the predictive power of a logistic regression model is the area under the Receiver Operating Characteristic (ROC) curve (for details see [9]). Areas of 0.5 and 1.0 correspond to chance performance and perfect performance of the model, respectively. Across the 40 logistic regression models that were fitted to the pooled trials from all experimental sessions, the area under the ROC curve ranged between 0.59 and 0.92 (M = 0.76, SD = 0.11), indicating on average reasonably good predictive power [28].
The individual normalized temporal weights estimated by the multiple logistic regressions were analyzed with repeated-measures analyses of variance (rmANOVAs) using a univariate approach with Huynh-Feldt correction for the degrees of freedom [29]. The correction factor ε˜ is reported, and partial η2 is reported as a measure of association strength. An α-level of .05 was used for all analyses.
Results
Fig 3 shows the mean normalized temporal weights in the five conditions. In each condition, a clear primacy effect was observed, in the sense that the weight on the first segment was higher than the weights on the following segments. For the condition in background noise where the mean segment level was 7.5 dB higher than the detection threshold in background noise (BGNSLBGN7.5), the primacy effect was slightly weaker than in the other conditions, and the mean weights on the final three segments were slightly higher than the weights for the middle segment, indicating a (weak) recency effect. Apart from this, the patterns of weights in the five conditions were similar.
An rmANOVA with the within-subjects factors condition (BGNSLBGN30, BGNSLBGN7.5, QuietSLBGN30, QuietSLBGN7.5, and QuietSLquiet7.5) and segment number (1–10) was conducted. There was a significant effect of segment number, F(9, 63) = 29.95, ε˜ = .494, p < .001, ηp2 = .811, confirming that the weights differed between the ten segments. The condition × segment number interaction was not significant, F(36, 252) = 1.91, ε˜ = .449, p = .058, ηp2 = .214, which indicates that masking and signal level had no significant effect on the pattern of temporal weights. To evaluate whether listeners adopted a decisional strategy during the experiment that eventually lead to the uniform weights across the different conditions, we also analyzed the weights from the logistic regressions that were fitted to the first and the last experimental session for each combination of listener and condition separately. An rmANOVA with the within-subjects factors condition (BGNSLBGN30, BGNSLBGN7.5, QuietSLBGN30, QuietSLBGN7.5, and QuietSLquiet7.5), segment number (1–10) and session (2,6) showed neither a significant main effect of session nor an interaction with session and any of the other factors. The relevant segment number × session and segment number × condition × session interactions both were not significant (F(9, 63) = 1.07, ε˜ = .855, p = .400, ηp2 = 0.132; F(36, 252) = 1.14, ε˜ = .509, p = .317, ηp2 = 0.141).
To quantify the magnitude and time course of the primacy effect, exponential decay functions were fitted to the mean weights at each of five conditions, as proposed in our previous work [10,11]. The weight assigned at the time t was assumed to be
The function w¯(ton,d) was fitted to the mean weights in each experimental condition separately, using the Mathematica function NonlinearModelFit, with the weight for a given data point wi proportional to 1/SDwi2, where SDwi2 is the variance of the eight individual estimated weights for segment i. Since only the time course of the primacy effect was of interest (and not potential recency effects), the function was fitted only to the first seven weights at the BGNSLBGN7.5 condition. Here, the remaining mean weights descriptively showed a weak recency effect. Fig 4 shows the fitted functions, together with the average decay function estimated on the basis of previous experiments [10]. The estimated parameters of the fitted decay functions are shown in Table 3. The exponential decay function provided an excellent fit to the mean weights in all five conditions (R2 ≥ 0.96). However, the standard errors of the estimated parameters in some of the conditions were larger than in the previous experiments [10]. This was particularly pronounced for the BGNSLBGN7.5 condition, where only 7 of the 10 segment weights were included in the fitting procedure due to the small recency effect. The size of the time constant τ was comparable to previous studies in which the estimated τ varied between 180 ms and 300 ms [10]. In the present data, the estimated τ was about 240 ms for the conditions in background noise, whereas for the conditions in quiet, τ varied between 217 and 355 ms. Previous studies showed a dynamic range Dr of about 4.70 for comparably long sound durations [10,11]. In the current study, a similar dynamic range (Dr = 5.05) was only found for condition QuietSLquiet7.5, whereas all other conditions showed higher dynamic ranges with Dr between 10 and 27.48.
The dashed blue lines in Fig 4 show the average decay function with τ = 280 ms and Dr = 4.70 [11]. This average function was fitted to the mean weights in each condition of our experiment, using only the multiplicative constant c as a free parameter. As seen in Table 2, the goodness of fit of this mean decay function (R2avg) was only minimally lower than for the specific decay function in all conditions. Thus, the average decay function provides a reasonably good description of the primacy effect in quiet as well as in the conditions in background noise. This confirms that the presence or absence of a background noise and variations in target level have a negligible effect on the primacy effect.
Discussion
Temporal loudness weights in background noise
In the present study, the influence of the acoustic background on temporal loudness weights was assessed for the first time by presenting the target sound either in quiet or in a continuous background noise. The presence of the background noise did not result in significant changes in the pattern of temporal weights compared to conditions without background noise. This is in agreement with findings of Oberfeld and Plank [7]. They concluded from their results that the primacy effect does not stem from an attention orientation response due to the abrupt onset of the sound. This conclusion can also be drawn from the results of the present experiment, in which the background noise was continuously presented during each experimental block, which, as we assumed in the introduction, should have reduced a potential attention orientating response to the onset of the target sound, relative to an in-quiet condition because the abruptness of the onset of the stimulus is reduced [16,17]. However, this is just an assumption based on the above mentioned research on attention capture in the visual domain, while to our knowledge, auditory attention orienting in quiet and with background noise has not been compared so far.
The absence of an effect of the background noise on the temporal weights is surprising considering that background noise affects the neuronal responses at several stages of the auditory pathway [22].
In addition to effects of background noise, we also investigated effects of the average target level. In quiet, a variation in mean level across a range of about 60 dB (from 7.5 dB above the individual threshold in quiet to 30 dB above the detection threshold in a 50-dB SPL background noise; see Table 2) had no significant effect on the temporal weights in the in-quiet condition. In background noise, the primacy effect was descriptively slightly less pronounced at the lower sound level compared to the higher sound level. Also, descriptively a small recency effect was observed at the lower sound level. However, the temporal weights did not differ significantly between the five experimental conditions. Taken together, varying the average target level across a wide range resulted only in surprisingly small effects on the temporal loudness weights. This pattern is at odds with an explanation of the primacy effect in terms of an orienting response, because as we mentioned in the introduction, a lower mean target level should have made the target sound onset less abrupt [16,17]. Again, the absence of a significant effect of target level on the weights is surprising because the responses of neurons at many stages of the auditory pathway are affected by the sound level.
One explanation of the primacy effect, which has been suggested in Dittrich and Oberfeld [9] is that it might be caused in a memory system, because it resembles the serial position effects commonly found in memory tasks. However, in Oberfeld et al. [10] this assumption was not supported. They presented sounds consisting of 20 segments and varied the length of the sounds between 1.0 s and 10.0 s. The data indicated that the weight assigned to a specific temporal portion of the sound is determined by the time delay between sound onset and segment onset, rather than by the relative position of the segment within the sound (i.e., segment number). In contrast, in memory experiments, the serial position curve is determined by the relative temporal position of the items within the item lists, while the time delay between the onset of the list and the given item plays only a minor role [30].
Another potential explanation we are currently evaluating is whether the effects may stem from an "evidence integration" or "sequential sampling" process in which evidence for one of the two possible hypotheses (“louder” or “softer” type of sounds) is collected sequentially during each trial and the decision is made as soon as sufficient information has been accumulated, ignoring further evidence during the trial [31,32]. Some recent papers found primacy (and sometimes recency) effects in visual motion perception [32] or brightness perception [33], using time-varying stimuli as in our experiment. These temporal weighting patterns can be modeled by accumulator or drift diffusion models. The authors of the respective papers thus suggested that the temporal weights are not caused at an early, sensory stage, but rather at a later decisional stage. An interesting prediction from this hypothesis is that within a participant, the temporal weights applied for instance in a loudness judgment task for sounds varying in level across time as in the present paper, and in a brightness judgment task for visual stimuli varying in brightness across time should be similar, because both of them are due to a certain type of evidence integration at the decision stage. We are currently testing this hypothesis in an experiment where participants receive randomly interleaved loudness-judgment and brightness-judgment trials.
Temporal weights predicted by a dynamic loudness model
To test if the observed loudness weights are predicted by an existing dynamic loudness model, the predictions of a model for the partial loudness of time-varying-sounds in background noise [34] were analyzed. The model, which we refer to as the time-varying partial loudness (TVPL) model, is based on the time-varying loudness (TVL) model by Glasberg and Moore [35]. The model was slightly modified by using the attack and decay time constants from the most current version of the TVL model [36]. An instantaneous partial loudness (IPL) is calculated from the predicted excitation patterns for signal and background noise [34]. The short-term partial loudness (STPL) is calculated by feeding the time series of IPL values into a temporal integration stage with an attack and a release time. The long-term partial loudness (LTPL) is calculated by feeding the time series of STPL values into another temporal integration stage with longer attack and release times than for STPL. The mean long-term loudness across the stimulus duration or its maximum were proposed to correspond to the overall loudness of a relatively long sound, such as a sentence or a musical phrase [37].
The loudness model was applied to the same set of experimental conditions and segment levels as in the experiment. In the experiment, a total of 38600 trials had been presented across the eight participants and the five experimental conditions. For each of these trials, a narrowband low-noise noise stimulus was generated using exactly the same sequence of 10 segment levels as in the corresponding trial of the experiment. This audio signal was fed into the loudness model, combined with a bandpass-filtered background noise of the same type and sound pressure level as in the corresponding trial, or without a background noise for the in-quiet conditions. To reduce the computation time, only 1 s of background noise was included before the onset of the stimulus. In the TVPL model, the long-term partial loudness is almost at its asymptotic value after 1 s, so that an inclusion of more than 1 s of background noise before signal onset would not have changed the simulation results. After stimulus offset, the background noise continued for 1.0 s, since in the experiment, the listeners typically responded within less than 1 s after target offset.
For each simulated trial, three statistics of STPL and LTPL were calculated. We selected the mean and the maximum because both were proposed to predict the overall perceived loudness [37]. We additionally included the 90th percentile of both STPL and LTPL because some authors assume that percentiles may be preferable in estimating loudness [4,38].
In the loudness model, the STPL and LTPL do not return to 0 immediately after sound offset, but level off gradually across about 300 ms (STPL) and several seconds (LTPL) due to the release time constants. To account for these temporal dynamics, the three statistics were calculated across a temporal window starting at stimulus onset and ending 300 ms or 1000 ms after stimulus offset for STPL and LTPL, respectively. At 1000 ms after stimulus offset, LTPL is still at approximately 30% of its value before stimulus offset. However, in the experiment the next trial typically started after 1 s, so that a longer time window for analyzing the LTPL would not have been realistic. To summarize, the mean (STPLmean), the maximum (STPLmax), and the 90th percentile (STPLpct) of the short term partial loudness were calculated across a period of 1300 ms, and the mean (LTPLmean), maximum (LTPLmax), and 90th percentile (LTPLpct) of the long term partial loudness were calculated across a period of 2000 ms on each simulated trial.
The a) ability of the loudness model to predict the responses of the listeners, and b) the temporal loudness weights predicted by the model were analyzed. Concerning a), separate logistic regression models were fitted for each combination of participant and experimental condition. For each simulated trial, the response of the participant in the experiment was used as the dependent variable, and a loudness statistic produced by the TVPL model (e.g., STPLmean) was entered as the predictor variable. The goodness-of-fit of the regression models based on the TVPL model were compared to the goodness-of-fit of the regression model based on the 10 segment levels that was used to analyze the data (see Fig 3). Fig 5 shows the resulting area under the ROC curve (AUC) for each of the regression models as an indicator of the goodness of fit. The regression based on the 10 segment levels provided the best fit to the data in quiet as well as in the presence of background noise at all signal levels. For a given TVPL-model loudness estimate (STPL, LTPL), the mean showed a better fit than the 90th percentile, which, in turn, showed a better fit than the maximum. This pattern was observed in each experimental condition. The AUCs for the conditions with the highest target level (BGNSLBGN30 & QuietSLBGN30) were higher than in the conditions with lower target levels. However, in the in-quiet conditions the AUCs were higher in the condition QuietSLquiet7.5 than in condition QuietSLBGN7.5, although the target level in the former condition was higher.
An rmANOVA with the seven different regression models (mean, maximum, and 90th-percentile STPL; mean, maximum, and 90th-percentile LTPL; 10-segment model) and the five experimental conditions as within-subjects factors showed a significant main effect of model, F(6, 42) = 79.00, ε˜ = .311, p < .001, ηp2 = .92. There was also a significant main effect of condition, F(4, 28) = 8.73, ε˜ = 1.0, p < .001, ηp2 = .56. The model × condition interaction was significant but relatively weak, F(24, 168) = 4.90, ε˜ = .305, p < .001, ηp2 = .41. As seen in Fig 5, the rank order of AUC across the seven models was identical in the five experimental conditions, but the exact difference between some models’ AUCs differed slightly as a function of experimental condition. Post-hoc pairwise comparisons were calculated between each of the TVPL-model based regression AUCs and the AUC of the regression based on the 10-segment model, averaged across experimental conditions. The AUC of the 10-segment model was significantly higher than the AUC of each of the TVPL-model based regression models (p < .01; Bonferroni-corrected). The minimum effect size in terms of Cohen’s dz [39] was 2.91, which represents a strong effect.
Concerning the temporal loudness weights predicted by the TVPL-model (b), each of the six loudness statistics produced by the TVPL model (e.g., STPLmean) were used to predict a response of either classifying the stimulus presented on the current trial as "louder" or classifying it as "softer", just as in the experiment. To this end, the given loudness statistic produced by the model (e.g., STPLmean) on a given trial was compared to the median of the same loudness statistic across all trials presenting the same experimental condition. If on a given trial the model loudness value was higher than this median value, the predicted response on this trial was "louder"; otherwise it was "softer". Next, exactly the same type of logistic regression model as we used for analyzing the psychoacoustic data was fitted for each of the five experimental conditions, except that the simulated response was used as the dependent variable rather than the observed response of the participants. Thus, the ten segment levels served as the predictors, and the simulated response served as the dependent variable. The regression coefficients were normalized as outlined in section Data analysis. Fig 6 shows the resulting normalized regression coefficients for each combination of summarizing statistic (mean, maximum, 90th percentile), model loudness value (STPL, LTPL), and experimental condition. For each TVPL model statistic, the pattern of temporal weights was relatively stable across the different sound levels and not strongly affected by the presence or absence of a background noise, just as in the psychoacoustic data. However, none of the six TVPL model statistics predicted a pattern of temporal weights similar to the weights observed in the experiment (Fig 3). The mean STPL, maximum STPL, and mean LTPL predicted essentially flat temporal weighting profiles. The 90th percentile of the STPL predicts slightly lower weights on the beginning and end of the sound, while the maximum and the 90th percentile of the LTPL predict an inverse U-shaped pattern with much lower weights on the beginning and/or end of the sound. Thus, none of the TVPL model statistics predicts the strong primacy effects observed in the experiment (see Fig 3).
Conclusion
The present study showed that the primacy effect, i.e., the assignment of higher weights to the beginning of a sound when judging loudness, occurs even in the presence of a background noise. As the onset of the continuous background noise occurred well before the presentation of the to-be-judged target sounds, mechanisms such as attention orientation seem to be unlikely to be the source of the primacy effect. In addition, the size of the primacy effect was largely independent of the sound level. The parameters of an exponential decay function describing the time course of the primacy effect were comparable to those obtained in earlier studies, emphasizing that the time course of the primacy effect was hardly affected by the experimental manipulations. None of the estimates of the time-varying partial loudness model [34] could predict the obtained weights. Thus, further research appears necessary to gather a better understanding of the mechanism(s) underlying the primacy effect and its time course.
Zdroje
1. Scharf B (1978) Loudness. In: Carterette EC, Friedman MP, editors. Handbook of Perception, Volume IV Hearing. New York: Academic Press. pp. 187–242.
2. Glasberg BR, Moore BC (2006) Prediction of absolute thresholds and equal-loudness contours using a modified loudness model. Journal of the Acoustical Society of America 120 : 585–588. doi: 10.1121/1.2214151 16938942
3. Jesteadt W, Leibold L (2011) Loudness in the Laboratory, Part I: Steady-State Sounds. In: Florentine M, Popper AN, Fay RR, editors. Loudness: Springer. pp. 109–144.
4. Chalupper J, Fastl H (2002) Dynamic loudness model (DLM) for normal and hearing-impaired listeners. Acta Acustica United with Acustica 88 : 378–386.
5. Rennies J, Verhey JL, Appell JE, Kollmeier B (2013) Loudness of complex time-varying sounds? A challenge for current loudness models. Proceedings of Meetings on Acoustics 19.
6. Rennies J, Wächtler M, Hots J, Verhey J (2015) Spectro-temporal characteristics affecting the loudness of technical sounds: Data and model predictions. Acta Acustica United with Acustica 101 : 1145–1156.
7. Oberfeld D, Plank T (2011) The temporal weighting of loudness: Effects of the level profile. Attention, Perception, & Psychophysics 73 : 189–208.
8. Pedersen B, Ellermeier W (2008) Temporal weights in the level discrimination of time-varying sounds. Journal of the Acoustical Society of America 123 : 963–972. doi: 10.1121/1.2822883 18247899
9. Dittrich K, Oberfeld D (2009) A comparison of the temporal weighting of annoyance and loudness. Journal of the Acoustical Society of America 126 : 3168–3178. doi: 10.1121/1.3238233 20000930
10. Oberfeld D, Hots J, Verhey JL (2018) Temporal weights in the perception of sound intensity: Effects of sound duration and number of temporal segments. Journal of the Acoustical Society of America 143 : 943–953. doi: 10.1121/1.5023686 29495718
11. Oberfeld D, Jung L, Verhey JL, Hots J (2018) Evaluation of a model of temporal weights in loudness judgments. Journal of the Acoustical Society of America 144: EL119–EL124. doi: 10.1121/1.5049895 30180681
12. Graham FK, Hackley SA (1991) Passive and active attention to input. In: Jennings JR, Coles MGH, editors. Handbook of cognitive psychophysiology: Central and autonomic nervous system approaches. Chichester, West Sussex, England; New York, NY, USA: Wiley. pp. 251–356.
13. Pavlov IP (1927) Conditioned reflexes: An investigation of the physiological activity of the cerebral cortex. Translated and edited by Anrep G. V. London: Oxford University Press.
14. Sechenov IM (1965) Reflexes of the brain (original publication 1863). Cambridge, Mass.: M.I.T. Press.
15. Koelewijn T, Bronkhorst A, Theeuwes J (2009) Auditory and visual capture during focused visual attention. Journal of Experimental Psychology: Human Perception and Performance 35 : 1303–1315. doi: 10.1037/a0013901 19803638
16. Jonides J, Yantis S (1988) Uniqueness of abrupt visual onset in capturing attention. Perception and Psychophysics 43 : 346–354.3362663
17. Ruz M, Lupiáñez J (2002) A review of attentional capture: On its automaticity and sensitivity to endogenous control. Psicológica 23 : 283–309.
18. Kiang NYS, Watanabe T, Thomas EC, Clark LF (1965) Discharge patterns of single fibers in the cat’s auditory nerve. Cambridge, Mass.: M.I.T. Press.
19. Nomoto M, Katsuki Y, Suga N (1964) Discharge pattern and inhibition of primary auditory nerve fibers in the monkey. Journal of Neurophysiology 27 : 768–787. doi: 10.1152/jn.1964.27.5.768 14205004
20. Yates GK, Robertson D, Johnstone BM (1985) Very rapid adaptation in the guinea-pig auditory-nerve. Hearing Research 17 : 1–12. doi: 10.1016/0378-5955(85)90124-8
21. Furukawa T, Matsuura S (1978) Adaptive rundown of excitatory post-synaptic potentials at synapses between hair cells and 8th nerve-fibers in goldfish. Journal of Physiology-London 276 : 193–209.
22. Simmons AM, Schwartz JJ, Ferragamo M (1992) Auditory-nerve representation of a complex communication sound in background-noise. Journal of the Acoustical Society of America 91 : 2831–2844. doi: 10.1121/1.402964
23. Oberfeld D (2008) Does a rhythmic context have an effect on perceptual weights in auditory intensity processing? Canadian Journal of Experimental Psychology-Revue Canadienne De Psychologie Experimentale 62 : 24–32. doi: 10.1037/1196-1961.62.1.24 18473626
24. Kohlrausch A, Fassel R, van der Heijden M, Kortekaas R, van de Par S, Oxenham AJ, et al. (1997) Detection of tones in low-noise noise: Further evidence for the role of envelope fluctuations. Acustica 83 : 659–669.
25. IEC 60318–1 : 1998 (1998) Electroacoustics—Simulators of human head and ear. Part 1: Ear simulator for the measurement of supra-aural and circumaural earphones. Geneva: International Electrotechnical Commission.
26. ISO 389–8 (2017) Acoustics—Reference zero for the calibration of audiometric equipment. Part 8: Reference equivalent threshold sound pressure levels for pure tones and circumaural earphones. Geneva.
27. Levitt H (1971) Transformed up-down methods in psychoacoustics. Journal of the Acoustical Society of America 49: Suppl 2 : 467–477.
28. Hosmer DW, Lemeshow S (2000) Applied logistic regression. New York: Wiley.
29. Huynh H, Feldt LS (1976) Estimation of the Box correction for degrees of freedom from sample data in randomized block and split-plot designs. Journal of Educational Statistics 1 : 69–82.
30. Murdock BB (1962) The serial position effect of free recall. Journal of Experimental Psychology 64 : 482–488.
31. Vickers D (1970) Evidence for an accumulator model of psychophysical discrimination. Ergonomics 13 : 37–58. doi: 10.1080/00140137008931117 5416868
32. Tsetsos K, Gao J, McClelland JL, Usher M (2012) Using time-varying evidence to test models of decision dynamics: bounded diffusion vs. the leaky competing accumulator model. Frontiers in Neuroscience 6.
33. Bronfman ZZ, Brezis N, Usher M (2016) Non-monotonic Temporal-Weighting Indicates a Dynamically Modulated Evidence-Integration Mechanism. Plos Computational Biology 12.
34. Glasberg BR, Moore BCJ (2005) Development and evaluation of a model for predicting the audibility of time-varying sounds in the presence of background sounds. Journal of the Audio Engineering Society 53 : 906–918.
35. Glasberg BR, Moore BCJ (2002) A model of loudness applicable to time-varying sounds. Journal of the Audio Engineering Society 50 : 331–342.
36. Moore BCJ, Jervis M, Harries L, Schlittenlacher J (2018) Testing and refining a loudness model for time-varying sounds incorporating binaural inhibition. Journal of the Acoustical Society of America 143 : 1504–1513. doi: 10.1121/1.5027246 29604698
37. Moore BCJ, Glasberg BR, Varathanathan A, Schlittenlacher J (2016) A loudness model for time-varying sounds incorporating binaural inhibition. Trends in Hearing 20.
38. Fastl H, Zwicker E (2007) Psychoacoustics: Facts and Models. Berlin: Springer.
39. Cohen J (1988) Statistical power analysis for the behavioral sciences. Hillsdale, N.J.: L. Erlbaum Associates.
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- Integrated pan-cancer gene expression and drug sensitivity analysis reveals SLFN11 mRNA as a solid tumor biomarker predictive of sensitivity to DNA-damaging chemotherapy
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- Morphology, phylogeny, and taxonomy of two species of colonial volvocine green algae from Lake Victoria, Tanzania
- Metabolomics profiles associated with HbA1c levels in patients with type 2 diabetes
- Exploring local realities: Perceptions and experiences of healthcare workers on the management and control of drug-resistant tuberculosis in Addis Ababa, Ethiopia
- Sex differences in the treatment and outcome of emergency general surgery
- Comorbidities and costs in HIV patients: A retrospective claims database analysis in Germany
- Barriers to integration of bioinformatics into undergraduate life sciences education: A national study of US life sciences faculty uncover significant barriers to integrating bioinformatics into undergraduate instruction
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- A comparison of body composition assessment methods in climbers: Which is better?
- Comparison of an in-house ‘home-brew’ and commercial ViroSeq integrase genotyping assays on HIV-1 subtype C samples
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- Clustering via hypergraph modularity
- Indomethacin enhances anti-tumor efficacy of a MUC1 peptide vaccine against breast cancer in MUC1 transgenic mice
- Multistage fuzzy comprehensive evaluation of landslide hazards based on a cloud model
- Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A
- Pharmacological signatures of the reduced incidence and the progression of cognitive decline in ageing populations suggest the protective role of beneficial polypharmacy
- Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the “von Magnus effect”
- Complex interaction networks of cytokines after transarterial chemotherapy in patients with hepatocellular carcinoma
- Gender essentialism in transgender and cisgender children
- Insertional mutagenesis in the zoonotic pathogen Chlamydia caviae
- Being there: A scoping review of grief support training in medical education
- Does the psychological profile influence the position of promising young futsal players?
- Effect of self-rated health status on functioning difficulties among older adults in Ghana: Coarsened exact matching method of analysis of the World Health Organization’s study on global AGEing and adult health, Wave 2
- Olfactory screening of Parkinson’s Disease patients and healthy subjects in China and Germany: A study of cross-cultural adaptation of the Sniffin’ Sticks 12-identification test
- Molecular evolution of cytochrome C oxidase-I protein of insects living in Saudi Arabia
- Correlates of leisure-time sedentary behavior among 181,793 adolescents aged 12-15 years from 66 low- and middle-income countries
- Cost-effectiveness analysis of Mucosal Leishmaniasis diagnosis with PCR-based vs parasitological tests in Colombia
- Spatiotemporal analysis of historical records (2001–2012) on dengue fever in Vietnam and development of a statistical model for forecasting risk
- Resilience assessment of Puerto Rico’s coral reefs to inform reef management
- Effect of community based health education on knowledge and attitude towards iron and folic acid supplementation among pregnant women in Kiambu County, Kenya: A quasi experimental study
- Implementation and effectiveness of non-specialist mediated interventions for children with Autism Spectrum Disorder: A systematic review and meta-analysis
- A tailored cognitive behavioral program for juvenile justice-referred females at risk of substance use and delinquency: A pilot quasi-experimental trial
- Impact of adjusted kidney volume measured in the bench surgery on one-year renal function in kidney transplantation
- Machine learning algorithm validation with a limited sample size
- The magnitude of suicidal ideation, attempts and associated factors of HIV positive youth attending ART follow ups at St. Paul’s hospital Millennium Medical College and St. Peter’s specialized hospital, Addis Ababa, Ethiopia, 2018
- The nonlinear effect of financial and fiscal policies on poverty alleviation in China—An empirical analysis of Chinese 382 impoverished counties with PSTR models
- Impacts of risk and competition on the profitability of banks: Empirical evidence from Pakistan
- Molecular characterization of lung adenocarcinoma from Korean patients using next generation sequencing
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- Joint image compression and encryption based on sparse Bayesian learning and bit-level 3D Arnold cat maps
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- Live observation of the oviposition process in Daphnia magna
- On the accuracy of displacement-based wave intensity analysis: Effect of vessel wall viscoelasticity and nonlinearity
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- A 3’ UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction
- Characterizing the Randot Preschool stereotest: Testability, norms, reliability, specificity and sensitivity in children aged 2-11 years
- Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells
- Amazon climatic factors driving terpene composition of Iryanthera polyneura Ducke in terra-firme forest: A statistical approach
- Differences in clinical features of cluster headache between drinkers and nondrinkers in Japan
- Distribution of macular ganglion cell layer thickness in foveal hypoplasia: A new diagnostic criterion for ocular albinism
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- Effect of mechanochemical activation of natural phosphorite structure as well as phosphorus solubility
- Automated content analysis across six languages
- A deep learning reconstruction framework for X-ray computed tomography with incomplete data
- Integrating interconception care in preventive child health care services: The Healthy Pregnancy 4 All program
- The prognostic significance of tumor-infiltrating lymphocytes assessment with hematoxylin and eosin sections in resected primary lung adenocarcinoma
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- Bacillus Calmette-Guérin (BCG) therapy lowers the incidence of Alzheimer’s disease in bladder cancer patients
- Serial block-face scanning electron microscopy reveals neuronal-epithelial cell fusion in the mouse cornea
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- Pragmatic language dysfunction in systemic lupus erythematosus patients: Results from a single center Italian study
- Association between cerebral atrophy and osteoporotic vertebral compression fractures
- Latitudinal gradient of cyanobacterial diversity in tidal flats
- Gene expression based survival prediction for cancer patients—A topic modeling approach
- Understanding allergic multimorbidity within the non-eosinophilic interactome
- The association between psychological distress and angina pectoris: A population-based study
- Comparative analysis on Facebook post interaction using DNN, ELM and LSTM
- Cerebellum-mediated trainability of eye and head movements for dynamic gazing
- Psychological and physiological effects of applying self-control to the mobile phone
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- Modulating transcription through development of semi-synthetic yeast core promoters
- Left-handed metamaterial bandpass filter for GPS, Earth Exploration-Satellite and WiMAX frequency sensing applications
- Cost-effectiveness analysis of PSA-based mass screening: Evidence from a randomised controlled trial combined with register data
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- Validation of the group tasks uncertainty model (MITAG) in a German sample
- Parent psychological wellbeing in a single-family room versus an open bay neonatal intensive care unit
- Optimizing the procedure of grain nutrient predictions in barley via hyperspectral imaging
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- Race disparity in blood sphingolipidomics associated with lupus cardiovascular comorbidity
- Characterization of the placental transcriptome through mid to late gestation in the mare
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- Diagnostic ability of multifocal electroretinogram in early multiple sclerosis using a new signal analysis method
- Predictors of never having a mammogram among Chinese, Vietnamese, and Korean immigrant women in the U.S.
- The impact of hepatic steatosis on portal hypertension
- How do and could clinical guidelines support patient-centred care for women: Content analysis of guidelines
- Study of the epidemiological behavior of malaria in the Darien Region, Panama. 2015–2017
- School-based obesity prevention for busy low-income families—Organisational and personal barriers and facilitators to implementation
- Neighborhood crime, disorder and substance use in the Caribbean context: Jamaica National Drug Use Prevalence Survey 2016
- Genomic comparison of diverse Salmonella serovars isolated from swine
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- Modeling of inter-organizational coordination dynamics in resilience planning of infrastructure systems: A multilayer network simulation framework
- Manipulating the odds: The effects of Machiavellianism and construal level on cheating behavior
- Early recognition of anorexia through patient-generated assessment predicts survival in patients with oesophagogastric cancer
- Identifying publications in questionable journals in the context of performance-based research funding
- ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico
- Nurses’ and patients’ experiences and preferences of the ankle-brachial pressure index and multi-site photoplethysmography for the diagnosis of peripheral arterial disease: A qualitative study
- Cluster tendency assessment in neuronal spike data
- Voluntary medical male circumcision for HIV prevention among adolescents in Kenya: Unintended consequences of pursuing service-delivery targets
- Primary care in five European countries: A citizens’ perspective on the quality of care for children
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- Psychometric properties of the Korean version of the Health Literacy on Social Determinants of Health Questionnaire (K-HL-SDHQ)
- Flood hazard mapping and assessment in data-scarce Nyaungdon area, Myanmar
- Methods for the identification of farm escapees in feral mink (Neovison vison) populations
- Transcriptional analysis of amino acid, metal ion, vitamin and carbohydrate uptake in butanol-producing Clostridium beijerinckii NRRL B-598
- Long-term vancomycin use had low risk of ototoxicity
- Overcoming platinum resistance in ovarian cancer by targeting pregnancy-associated plasma protein-A
- Exploration of muscle loss and metabolic state during prolonged critical illness: Implications for intervention?
- Pan-caspase inhibitor F573 mitigates liver ischemia reperfusion injury in a murine model
- Efficacy of interleukin 10 gene hydrofection in pig liver vascular isolated ‘in vivo’ by surgical procedure with interest in liver transplantation
- Molecular characteristics of segment 5, a unique fragment encoding two partially overlapping ORFs in the genome of rice black-streaked dwarf virus
- Early economic evaluation of MRI-guided laser interstitial thermal therapy (MRgLITT) and epilepsy surgery for mesial temporal lobe epilepsy
- GLADS: A gel-less approach for detection of STMS markers in wheat and rice
- Anterior tooth-use behaviors among early modern humans and Neandertals
- Incidence patterns of orofacial clefts in purebred dogs
- Capacity of the medullary cavity of tibia and femur for intra-bone marrow transplantation in mice
- Association of thoracic spine deformity and cardiovascular disease in a mouse model for Marfan syndrome
- Predicting atrial fibrillation in primary care using machine learning
- M3VR—A multi-stage, multi-resolution, and multi-volumes-of-interest volume registration method applied to 3D endovaginal ultrasound
- A developmental trajectory supporting the evaluation and achievement of competencies: Articulating the Mastery Rubric for the nurse practitioner (MR-NP) program curriculum
- Mobile medication manager application to improve adherence with immunosuppressive therapy in renal transplant recipients: A randomized controlled trial
- Default Mode Network structural alterations in Kocher-Monro trajectory white matter transection: A 3 and 7 tesla simulation modeling approach
- Phylogenetic revision of Gymnotidae (Teleostei: Gymnotiformes), with descriptions of six subgenera
- Population genetic analysis of 36 Y-chromosomal STRs yields comprehensive insights into the forensic features and phylogenetic relationship of Chinese Tai-Kadai-speaking Bouyei
- Prevention of suicidal behaviour: Results of a controlled community-based intervention study in four European countries
- An assessment of khat consumption habit and its linkage to household economies and work culture: The case of Harar city
- Fixation of genetic variation and optimization of gene expression: The speed of evolution in isolated lizard populations undergoing Reverse Island Syndrome
- One simple claudication question as first step in Peripheral Arterial Disease (PAD) screening: A meta-analysis of the association with reduced Ankle Brachial Index (ABI) in 27,945 subjects
- Direct cost of health care for individuals with community associated Clostridium difficile infections: A population-based cohort study
- Association between serum homocysteine level and cognitive function in middle-aged type 2 diabetes mellitus patients
- A qualitative research synthesis of contextual factors contributing to female overweight and obesity over the life course in sub-Saharan Africa
- Insight into the relationship between aryl-hydrocarbon receptor and β-catenin in human colon cancer cells
- Hidden noise in immunologic parameters might explain rapid progression in early-onset periodontitis
- The role of stigma in the acceptance and disclosure of HIV among recently diagnosed men who have sex with men in Australia: A qualitative study
- Detection of Schistosoma japonicum and Oncomelania hupensis quadrasi environmental DNA and its potential utility to schistosomiasis japonica surveillance in the Philippines
- Does age influence the quality of life in children with atopic dermatitis?
- Questioning the lasting effect of galvanic vestibular stimulation on postural control
- Identification of a novel monocytic phenotype in Classic Hodgkin Lymphoma tumor microenvironment
- Characterization of 20 complete plastomes from the tribe Laureae (Lauraceae) and distribution of small inversions
- Binding and dynamics of melatonin at the interface of phosphatidylcholine-cholesterol membranes
- Recent climate-driven ecological change across a continent as perceived through local ecological knowledge
- Nonalcoholic fatty liver disease is an early predictor of metabolic diseases in a metabolically healthy population
- Occurrence and multilocus genotyping of Giardia duodenalis from post-weaned dairy calves in Sichuan province, China
- Retinoic acid-stimulated ERK1/2 pathway regulates meiotic initiation in cultured fetal germ cells
- Gender disparities in scientific production: A nationwide assessment among physicians in Peru
- Effect of F1 and F2 generations on genetic variability and working steps of doubled haploid production in maize
- Mitochondrial dysfunction in rheumatoid arthritis: A comprehensive analysis by integrating gene expression, protein-protein interactions and gene ontology data
- A caspase-6-cleaved fragment of Glial Fibrillary Acidic Protein as a potential serological biomarker of CNS injury after cardiac arrest
- A handy method to remove bacterial contamination from fungal cultures
- The self-care profiles and its determinants among adults with hypertension in primary health care clinics in Selangor, Malaysia
- The mutational landscape of quinolone resistance in Escherichia coli
- Exploring the influence of self-perceptions on the relationship between motor competence and identity in adolescents
- Study on the damage characteristics of gas-bearing shale under different unloading stress paths
- EPILAT-IRA Study: A contribution to the understanding of the epidemiology of acute kidney injury in Latin America
- 16S rDNA droplet digital PCR for monitoring bacterial DNAemia in bloodstream infections
- Three-dimensional (3D) brain microphysiological system for organophosphates and neurochemical agent toxicity screening
- Diversity of endocervical microbiota associated with genital Chlamydia trachomatis infection and infertility among women visiting obstetrics and gynecology clinics in Malaysia
- Health impact of hepatic-venous-occlusive disease in a small town in Ethiopia—Case study from Tahtay koraro district in Tigray region, 2017
- Development of a novel automatable fabrication method based on electrospinning co electrospraying for rotator cuff augmentation patches
- Development of a quantitative PCR assay for the detection and enumeration of a potentially ciguatoxin-producing dinoflagellate, Gambierdiscus lapillus (Gonyaulacales, Dinophyceae)
- Association of clinical factors with survival outcomes in laryngeal squamous cell carcinoma (LSCC)
- Seasonal oyster harvesting recorded in a Late Archaic period shell ring
- Population preferences for breast cancer screening policies: Discrete choice experiment in Belarus
- Respiratory health and inflammatory markers - Exposure to respirable dust and quartz and chemical binders in Swedish iron foundries
- Trends and predictors of mother-to-child transmission of HIV in an era of protocol changes: Findings from two large health facilities in North East Nigeria
- Elevated Ki-67 (MIB-1) expression as an independent predictor for unfavorable pathologic outcomes and biochemical recurrence after radical prostatectomy in patients with localized prostate cancer: A propensity score matched study
- Genome-wide identification and gene expression analysis of SOS family genes in tuber mustard (Brassica juncea var. tumida)
- Carvedilol improves glucose tolerance and insulin sensitivity in treatment of adrenergic overdrive in high fat diet-induced obesity in mice
- Institutional differences in USMLE Step 1 and 2 CK performance: Cross-sectional study of 89 US allopathic medical schools
- Molecular epidemiological characteristics of dengue virus carried by 34 patients in Guangzhou in 2018
- Heteroplasmy in the complete chicken mitochondrial genome
- Candida blood stream infections observed between 2011 and 2016 in a large Italian University Hospital: A time-based retrospective analysis on epidemiology, biofilm production, antifungal agents consumption and drug-susceptibility
- Sixty years since the creation of Lake Kariba: Thermal and oxygen dynamics in the riverine and lacustrine sub-basins
- Association of uric acid in serum and urine with subclinical renal damage: Hanzhong Adolescent Hypertension Study
- Appropriate management of acute gastroenteritis in Australian children: A population-based study
- The plasma metabolome of women in early pregnancy differs from that of non-pregnant women
- Effectiveness of four types of neuraminidase inhibitors approved in Japan for the treatment of influenza
- More than just availability: Who has access and who administers take-home naloxone in Baltimore, MD
- Evaluating the cross-cultural validity of the Dutch version of the Social Exclusion Index for Health Surveys (SEI-HS): A mixed methods study
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- Serum uromodulin is associated with the severity of clinicopathological findings in ANCA-associated glomerulonephritis
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- ADAPTS: Automated deconvolution augmentation of profiles for tissue specific cells
- Comparison of shape quantification methods for genomic prediction, and genome-wide association study of sorghum seed morphology
- An attempt to identify the issues underlying the lack of consistent conceptualisations in the field of student mathematics-related beliefs
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- Effects of light and nitrogen availability on photosynthetic efficiency and fatty acid content of three original benthic diatom strains
- Early signal detection of adverse events following influenza vaccination using proportional reporting ratio, Victoria, Australia
- Bioinformatic analysis of a novel Echinococcus granulosus nuclear receptor with two DNA binding domains
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- Involvement of extracellular vesicles in the macrophage-tumor cell communication in head and neck squamous cell carcinoma
- Comparison of Humphrey Field Analyzer and imo visual field test results in patients with glaucoma and pseudo-fixation loss
- Out-of-pocket expenditure and catastrophic health expenditure for hospitalization due to injuries in public sector hospitals in North India
- Concurrent validity and discriminative ability of Dutch performance-based motor tests in 5 to 6 years old children
- Cumulative viral load as a predictor of CD4+ T-cell response to antiretroviral therapy using Bayesian statistical models
- Can General Practitioners manage mental disorders in primary care? A partially randomised, pragmatic, cluster trial
- Self-serving incentives impair collective decisions by increasing conformity
- Mutation and immune profiling of metaplastic breast cancer: Correlation with survival
- The clinicopathological significance of Thrombospondin-4 expression in the tumor microenvironment of gastric cancer
- Propofol-based total intravenous anesthesia did not improve survival compared to desflurane anesthesia in breast cancer surgery
- Association between ossification of the posterior longitudinal ligament and ossification of the nuchal ligament in the cervical spine
- Effects of Debaryomyces hansenii treatment on intestinal mucosa microecology in mice with antibiotic-associated diarrhea
- Molecular validation of clinical Pantoea isolates identified by MALDI-TOF
- A novel wheat lodging resistance evaluation method and device based on the thrust force of the stalks
- Evolution of high tooth replacement rates in theropod dinosaurs
- Outpatient facility-based order variation in combined imaging
- Ethnic-racial identity affirmation: Validation in Aboriginal Australian children
- Non-intubated anesthesia in patients undergoing video-assisted thoracoscopic surgery: A systematic review and meta-analysis
- Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages
- Changes of serum pentraxin-3 and hypersensitive CRP levels during pregnancy and their relationship with gestational diabetes mellitus
- Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake
- Investigating reindeer pastoralism and exploitation of high mountain zones in northern Mongolia through ice patch archaeology
- Diversity pattern of Plasmodium knowlesi merozoite surface protein 4 (MSP4) in natural population of Malaysia
- Protein synthesis rates of muscle, tendon, ligament, cartilage, and bone tissue in vivo in humans
- “What gets measured better gets done better”: The landscape of validation of global maternal and newborn health indicators through key informant interviews
- Contactless monitoring of heart and respiratory rate in anesthetized pigs using infrared thermography
- Molecular characterisation of genital human papillomavirus among women in Southwestern, Nigeria
- The impact of “male clinics” on health-seeking behaviors of adult men in rural Kenya
- Gene expression microarray public dataset reanalysis in chronic obstructive pulmonary disease
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- Maternal diet modulates placental nutrient transporter gene expression in a mouse model of diabetic pregnancy
- Effects of an incremental theory of personality intervention on the reciprocity between bullying and cyberbullying victimization and perpetration in adolescents
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- Reproducibility, stability, and accuracy of microbial profiles by fecal sample collection method in three distinct populations
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- Variation in hybridogenetic hybrid emergence between populations of water frogs from the Pelophylax esculentus complex
- Breast cancer in Tanzanian, black American, and white American women: An assessment of prognostic and predictive features, including tumor infiltrating lymphocytes
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- High salinity tolerance of invasive blue catfish suggests potential for further range expansion in the Chesapeake Bay region
- From waste to food: Optimising the breakdown of oil palm waste to provide substrate for insects farmed as animal feed
- Quantitative assessment of interstitial lung disease in Sjögren’s syndrome
- Comparative efficacy of tenofovir and entecavir in nucleos(t)ide analogue-naive chronic hepatitis B: A systematic review and meta-analysis
- Reference ranges for ultrasonographic renal dimensions as functions of age and body indices: A retrospective observational study in Taiwan
- Finding phrases: On the role of co-verbal facial information in learning word order in infancy
- Mathematical modeling reveals the factors involved in the phenomena of cancer stem cells stabilization
- Effects of forest management and roe deer impact on a mountain forest development in the Italian Apennines: A modelling approach using LANDIS-II
- Evaluation of comprehensive improvement for mild and moderate soil salinization in arid zone
- Efficacy, acceptability and feasibility of daily text-messaging in promoting glycaemic control and other clinical outcomes in a low-resource setting of South Africa: A randomised controlled trial
- Magnitude and associated factors of postpartum depression among women in Nekemte town, East Wollega zone, west Ethiopia, 2019: A community-based study
- Comparison of continuous wave and cold lateral condensation filling techniques in 3D printed simulated C-shape canals instrumented with Reciproc Blue or Hyflex EDM
- Effect of caffeine on neuromuscular function following eccentric-based exercise
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- The gut microbiome of freshwater Unionidae mussels is determined by host species and is selectively retained from filtered seston
- Alcohol consumption and survival after breast cancer diagnosis in Japanese women: A prospective patient cohort study
- Selection of reference genes for normalization of cranberry (Vaccinium macrocarpon Ait.) gene expression under different experimental conditions
- The household economic costs associated with depression symptoms: A cross-sectional household study conducted in the North West province of South Africa
- Increased cell size, structural complexity and migration of cancer cells acquiring fibroblast organelles by cell-projection pumping
- Acute low- compared to high-load resistance training to failure results in greater energy expenditure during exercise in healthy young men
- Impact of body mass index and metabolically unhealthy status on mortality in the Japanese general population: The JMS cohort study
- Characterization of two thermophilic cellulases from Talaromyces leycettanus JCM12802 and their synergistic action on cellulose hydrolysis
- Ecohydrology of urban trees under passive and active irrigation in a semiarid city
- Cyclosporine A eyedrops with self-nanoemulsifying drug delivery systems have improved physicochemical properties and efficacy against dry eye disease in a murine dry eye model
- LFastqC: A lossless non-reference-based FASTQ compressor
- Highly accurate prediction of flammability limits of chemical compounds using novel integrated hybrid models
- Nonsteroidal anti-inflammatory drugs and acetaminophen ameliorate muscular mechanical hyperalgesia developed after lengthening contractions via cyclooxygenase-2 independent mechanisms in rats
- A popular Indian clove-based mosquito repellent is less effective against Culex quinquefasciatus and Aedes aegypti than DEET
- Yeasts affect tolerance of Drosophila melanogaster to food substrate with high NaCl concentration
- The effect of climate change on cholera disease: The road ahead using artificial neural network
- Grit (effortful persistence) can be measured with a short scale, shows little variation across socio-demographic subgroups, and is associated with career success and career engagement
- Micro-dislodgement during transcatheter aortic valve implantation with a contemporary self-expandable prosthesis
- Improving the antimicrobial efficacy against resistant Staphylococcus aureus by a combined use of conjugated oligoelectrolytes
- Kin discrimination and outer membrane exchange in Myxococcus xanthus: Experimental analysis of a natural population
- Inflammatory cell infiltrates, hypoxia, vascularization, pentraxin 3 and osteoprotegerin in abdominal aortic aneurysms – A quantitative histological study
- Effects of virtual reality rehabilitation training on gait and balance in patients with Parkinson's disease: A systematic review
- Serum miR-33a is associated with steatosis and inflammation in patients with non-alcoholic fatty liver disease after liver transplantation
- Association between housing tenure and self-rated health in Japan: Findings from a nationwide cross-sectional survey
- Investigation of biochemical and physiological parameters of the newborn Saiga antelope (Saiga tatarica) in Gansu Province, China
- One-year follow-up of changes in refraction and aberrations induced by corneal incision
- Evaluation of upper limb superficial venous percussion as a sign of anatomical location and venous permeability. A comparative study of superficial venous percussion to ultrasound findings on non-renal patients and on chronic kidney disease patients
- An assessment of the Dutch experience with health insurers acting as healthcare advisors
- Perception of potential harm and benefits of HIV vaccine trial participation: A qualitative study from urban Tanzania
- Veterans with Gulf War Illness exhibit distinct respiratory patterns during maximal cardiopulmonary exercise
- Deep brain stimulation restores the glutamatergic and GABAergic synaptic transmission and plasticity to normal levels in kindled rats
- Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals
- Cranberry extracts promote growth of Bacteroidaceae and decrease abundance of Enterobacteriaceae in a human gut simulator model
- Long-term retention on antiretroviral therapy among infants, children, adolescents and adults in Malawi: A cohort study
- Histochemical quantification of collagen content in articular cartilage
- Optogenetically transduced human ES cell-derived neural progenitors and their neuronal progenies: Phenotypic characterization and responses to optical stimulation
- Ion torrent high throughput mitochondrial genome sequencing (HTMGS)
- Outpatient antibiotic prescription rate and pattern in the private sector in India: Evidence from medical audit data
- Acute Influenza A virus outbreak in an enzootic infected sow herd: Impact on viral dynamics, genetic and antigenic variability and effect of maternally derived antibodies and vaccination
- Prevalence and correlates of low serum calcium in late pregnancy: A cross sectional study in the Nkongsamba Regional Hospital; Littoral Region of Cameroon
- Home-cage monitoring ascertains signatures of ictal and interictal behavior in mouse models of generalized seizures
- CRISPR/Cas9 gene editing in the West Nile Virus vector, Culex quinquefasciatus Say
- Genetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches
- Proton pump inhibitor use increases the risk of peritonitis in peritoneal dialysis patients
- Comparative distribution of extended-spectrum beta-lactamase–producing Escherichia coli from urine infections and environmental waters
- Sex differences in thigh muscle volumes, sprint performance and mechanical properties in national-level sprinters
- Maternal serum and cord blood leptin concentrations at delivery
- Winter nitrification in ice-covered lakes
- Intolerance of uncertainty fuels depressive symptoms through rumination: Cross-sectional and longitudinal studies
- Monitoring exercise-induced muscle damage indicators and myoelectric activity during two weeks of knee extensor exercise training in young and old men
- Can adoption of pollution prevention techniques reduce pollution substitution?
- The association between self-efficacy and self-management behaviors among Chinese patients with type 2 diabetes
- Poly-arginine-18 peptides do not exacerbate bleeding, or improve functional outcomes following collagenase-induced intracerebral hemorrhage in the rat
- Affective disorders in the elderly in different European countries: Results from the MentDis_ICF65+ study
- Evaluation of forearm vascular resistance during orthostatic stress: Velocity is proportional to flow and size doesn’t matter
- Proton pencil minibeam irradiation of an in-vivo mouse ear model spares healthy tissue dependent on beam size
- Maternal stress in Shank3ex4-9 mice increases pup-directed care and alters brain white matter in male offspring
- Aspartate aminotransferase-to-platelet ratio index (APRI): A potential marker for diagnosis in patients at risk of severe malaria caused by Plasmodium vivax
- Exploiting open source 3D printer architecture for laboratory robotics to automate high-throughput time-lapse imaging for analytical microbiology
- Long non-coding RNAs and latent HIV – A search for novel targets for latency reversal
- Clinical characteristics of neonatal fulminant necrotizing enterocolitis in a tertiary Children's hospital in the last 10 years
- Effects of neuromuscular electrical stimulation training on muscle size in collegiate track and field athletes
- Adaptive fuzzy flow rate control considering multifractal traffic modeling and 5G communications
- Evaluation of four commercial tests for detecting ceftiofur in waste milk bulk tank samples
- A smart tele-cytology point-of-care platform for oral cancer screening
- Vasopressin SNP pain factors and stress in sickle cell disease
- Carbonate production of Micronesian reefs suppressed by thermal anomalies and Acanthaster as sea-level rises
- Microbial metabolisms in an abyssal ferromanganese crust from the Takuyo-Daigo Seamount as revealed by metagenomics
- Incidence of chronic kidney disease hospitalisations and mortality in Espírito Santo between 1996 to 2017
- The impact of short-term machine perfusion on the risk of cancer recurrence after rat liver transplantation with donors after circulatory death
- Proteomic profiling of the thrombin-activated canine platelet secretome (CAPS)
- Blood metal levels and serum testosterone concentrations in male and female children and adolescents: NHANES 2011–2012
- The effects of prolonged single night session of videogaming on sleep and declarative memory
- Diversity, distribution and dynamics of large trees across an old-growth lowland tropical rain forest landscape
- Mapping developmental QTL for plant height in soybean [Glycine max (L.) Merr.] using a four-way recombinant inbred line population
- Vaginal ring acceptability and related preferences among women in low- and middle-income countries: A systematic review and narrative synthesis
- UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal
- Positive selection and precipitation effects on the mitochondrial NADH dehydrogenase subunit 6 gene in brown hares (Lepus europaeus) under a phylogeographic perspective
- Evaluation of Minimum Inhibitory Concentrations for 154 Mycoplasma synoviae isolates from Italy collected during 2012-2017
- Enhancement of antibiotics antimicrobial activity due to the silver nanoparticles impact on the cell membrane
- Correction: Smoking, alcohol use disorder and tuberculosis treatment outcomes: A dual co-morbidity burden that cannot be ignored
- Correction: Effect of corruption on perceived difficulties in healthcare access in sub-Saharan Africa
- Knowledge-based best of breed approach for automated detection of clinical events based on German free text digital hospital discharge letters
- Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects
- Integrated value-chain and risk assessment of Pig-Related Zoonoses in Ghana
- Failed sperm retrieval from severely oligospermic or non-obstructive azoospermic patients on oocyte retrieval day: Emergent oocyte cryopreservation is a feasible strategy
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- Verification of hub genes in the expression profile of aortic dissection
- Pig farmers’ willingness to pay for management strategies to reduce aggression between pigs
- Metabolomic response of Euglena gracilis and its bleached mutant strain to light
- Diagnostic value of ASVS for insulinoma localization: A systematic review and meta-analysis
- Newly educated care managers’ experiences of providing care for persons with stress-related mental disorders in the clinical primary care context
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- Qualification programmes for immigrant health professionals: A systematic review
- An analytical model to minimize the latency in healthcare internet-of-things in fog computing environment
- Grain filling of early-season rice cultivars grown under mechanical transplanting
- Intercalation of small molecules into DNA in chromatin is primarily controlled by superhelical constraint
- Correlative evidence for co-regulation of phosphorus and carbon exchanges with symbiotic fungus in the arbuscular mycorrhizal Medicago truncatula
- How to design a dose-finding study on combined agents: Choice of design and development of R functions
- Altered expression of Notch1 in Alzheimer's disease
- The ZJU index is a powerful surrogate marker for NAFLD in severely obese North American women
- Trunk velocity-dependent Light Touch reduces postural sway during standing
- Evaluation of cytological diagnostic accuracy for canine splenic neoplasms: An investigation in 78 cases using STARD guidelines
- Trade-offs in motivating volunteer effort: Experimental evidence on voluntary contributions to science
- Does caching strategy vary with microclimate in endangered Mt. Graham red squirrels?
- Assessment of energy expenditure during high intensity cycling and running using a heart rate and activity monitor in young active adults
- Evaluating rectal swab collection method for gut microbiome analysis in the common marmoset (Callithrix jacchus)
- Implementation of a screening, brief intervention and referral to treatment programme for risky substance use in South African emergency centres: A mixed methods evaluation study
- Can the CalproQuest predict a positive Calprotectin test? A prospective diagnostic study
- The calcium sensor OsCBL1 modulates nitrate signaling to regulate seedling growth in rice
- Acceptability of and treatment preferences for recurrent bacterial vaginosis—Topical lactic acid gel or oral metronidazole antibiotic: Qualitative findings from the VITA trial
- Mathematical determination of the HIV-1 matrix shell structure and its impact on the biology of HIV-1
- Contingent negative variation during a modified cueing task in simulated driving
- CAMDI interacts with the human memory-associated protein KIBRA and regulates AMPAR cell surface expression and cognition
- Effect of feeding patterns on growth and nutritional status of children aged 0-24 months: A Chinese cohort study
- A fecal sequel: Testing the limits of a genetic assay for bat species identification
- Measuring the impact of chronic conditions and associated multimorbidity on health-related quality of life in the general population in Hong Kong SAR, China: A cross-sectional study
- Short and long-term clinical effectiveness and cost-effectiveness of a late-phase community-based balance and gait exercise program following hip fracture. The EVA-Hip Randomised Controlled Trial
- Vaccine cold chain in general practices: A prospective study in 75 refrigerators (Keep Cool study)
- Brazilian norms for the Bank of Standardized Stimuli (BOSS)
- Distinct varieties of aesthetic chills in response to multimedia
- Interaction between apolipoprotein E genotype and hypertension on cognitive function in older women in the Nurses’ Health Study
- Correction: Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study
- New formulation of the Gompertz equation to describe the kinetics of untreated tumors
- Development of visual perception of others’ actions: Children’s judgment of lifted weight
- Retrospective comparative analysis of intraocular lens calculation formulas after hyperopic refractive surgery
- Human vitreous concentrations of citicoline following topical application of citicoline 2% ophthalmic solution
- Development and validation of exhaled breath condensate microRNAs to identify and endotype asthma in children
- Arthroscopic release for frozen shoulder: Does the timing of intervention and diabetes affect outcome?
- Risk factors affecting dairy cattle protective grouping behavior, commonly known as bunching, against Stomoxys calcitrans (L.) on California dairies
- Acceleration of chemical shift encoding-based water fat MRI for liver proton density fat fraction and T2* mapping using compressed sensing
- Characterisation and microbial community analysis of lipid utilising microorganisms for biogas formation
- Sexuality in male partners of women with fibromyalgia syndrome: A qualitative study
- Exploring optimization strategies for improving explicit water models: Rigid n-point model and polarizable model based on Drude oscillator
- Artificial insemination with fresh, liquid stored and frozen thawed semen in dromedary camels
- Moving into an urban drug scene among people who use drugs in Vancouver, Canada: Latent class growth analysis
- Numerical study on the start and unstart phenomena in a scramjet inlet-isolator model
- Effects of dietary supplementation with apple peel powder on the growth, blood and liver parameters, and transcriptome of genetically improved farmed tilapia (GIFT, Oreochromis niloticus)
- Urban growth simulation in different scenarios using the SLEUTH model: A case study of Hefei, East China
- Chronic bronchitis without airflow obstruction, asthma and rhinitis are differently associated with cardiovascular risk factors and diseases
- Factors associated with medication adherence among people with diabetes mellitus in poor urban areas of Cambodia: A cross-sectional study
- Mammary microbiome of lactating organic dairy cows varies by time, tissue site, and infection status
- Force field generalization and the internal representation of motor learning
- Polyphenism of visual and chemical secondary sexually-selected wing traits in the butterfly Bicyclus anynana: How different is the intermediate phenotype?
- Minimal genetic differentiation of the malaria vector Nyssorhynchus darlingi associated with forest cover level in Amazonian Brazil
- The impact of leisure activities on older adults’ cognitive function, physical function, and mental health
- scafSLICR: A MATLAB-based slicing algorithm to enable 3D-printing of tissue engineering scaffolds with heterogeneous porous microarchitecture
- Association of serum leptin and adiponectin concentrations with echocardiographic parameters and pathophysiological states in patients with cardiovascular disease receiving cardiovascular surgery
- Operation of cognitive memory inhibition in adults with Down syndrome: Effects of maintenance load and material
- Influences on surgical antimicrobial prophylaxis decision making by surgical craft groups, anaesthetists, pharmacists and nurses in public and private hospitals
- Post-treatment Lyme disease symptoms score: Developing a new tool for research
- Expression of Concern: The Role of the RACK1 Ortholog Cpc2p in Modulating Pheromone-Induced Cell Cycle Arrest in Fission Yeast
- Equine bronchial fibroblasts enhance proliferation and differentiation of primary equine bronchial epithelial cells co-cultured under air-liquid interface
- Investigating cooperation with robotic peers
- Synthesis, purification and crystallization of a putative critical bulge of HAR1 RNA
- Prosthetic push-off power in trans-tibial amputee level ground walking: A systematic review
- A case study of the use of verbal reports for talent identification purposes in soccer: A Messi affair!
- Transgenerational deep sequencing revealed hypermethylation of hippocampal mGluR1 gene with altered mRNA expression of mGluR5 and mGluR3 associated with behavioral changes in Sprague Dawley rats with history of prolonged febrile seizure
- Obesity is associated with an impaired survival in lymphoma patients undergoing autologous stem cell transplantation
- Periodontal disease: Repercussions in pregnant woman and newborn health—A cohort study
- Origins of Chinese reindeer (Rangifer tarandus) based on mitochondrial DNA analyses
- Regional, racial, gender, and tumor biology disparities in breast cancer survival rates in Africa: A systematic review and meta-analysis
- How effective are films in inducing positive and negative emotional states? A meta-analysis
- 3D nanostructural characterisation of grain boundaries in atom probe data utilising machine learning methods
- An outbreak of tuberculosis in a middle school in Henan, China: Epidemiology and risk factors
- Initial clinical radiological findings and staging to predict prognosis of primary hepatic angiosarcoma: A retrospective analysis
- A new early Eocene deperetellid tapiroid illuminates the origin of Deperetellidae and the pattern of premolar molarization in Perissodactyla
- Longevity and marginal bone loss of narrow-diameter implants supporting single crowns: A systematic review
- Impact of UVC-sustained recirculating air filtration on airborne bacteria and dust in a pig facility
- Cold-related Florida manatee mortality in relation to air and water temperatures
- Conceptual fluency in inductive reasoning
- Clinical outcomes and treatment patterns among Medicare patients with nonvalvular atrial fibrillation (NVAF) and chronic kidney disease
- Improvements in the learnability of smartphone haptic interfaces for visually impaired users
- Role of the malic enzyme in metabolism of the halotolerant methanotroph Methylotuvimicrobium alcaliphilum 20Z
- Cyclic loading test study on a new cast-in-situ insulated sandwich concrete wall
- Natural compounds as angiogenic enzyme thymidine phosphorylase inhibitors: In vitro biochemical inhibition, mechanistic, and in silico modeling studies
- Analysis of virulence potential of Escherichia coli O145 isolated from cattle feces and hide samples based on whole genome sequencing
- Pre-clinical medical student reflections on implicit bias: Implications for learning and teaching
- Prognostic significance of non-sustained ventricular tachycardia on stored electrograms in pacemaker recipients
- Determinants of preterm birth among mothers who gave birth at public hospitals in the Amhara region, Ethiopia: A case-control study
- Real-world evidence of the effectiveness of ombitasvir-paritaprevir/r ± dasabuvir ± ribavirin in patients monoinfected with chronic hepatitis C or coinfected with human immunodeficiency virus-1 in Spain
- Unique transcriptomic landscapes identified in idiopathic spontaneous and infection related preterm births compared to normal term births
- Restrained expansion of the recall germinal center response as biomarker of protection for influenza vaccination in mice
- Arabidopsis TRM5 encodes a nuclear-localised bifunctional tRNA guanine and inosine-N1-methyltransferase that is important for growth
- Achievement of weight loss in patients with overweight during dietetic treatment in primary health care
- Autophagy deficiency exacerbates colitis through excessive oxidative stress and MAPK signaling pathway activation
- The impacts of parity on lung function data (LFD) of healthy females aged 40 years and more issued from an upper middle income country (Algeria): A comparative study
- Reorganization of spatial configurations in visual working memory: A matter of set size?
- Unravelling travellers’ route choice behaviour at full-scale urban network by focusing on representative OD pairs in computer experiments
- Evaluating the higher-order structure of the Profile of Emotional Competence (PEC): Confirmatory factor analysis and Bayesian structural equation modeling
- HIV prevalence and correlated factors among male clients of female sex workers in a border region of China
- Next generation sequencing and RNA-seq characterization of adipose tissue in the Nile crocodile (Crocodylus niloticus) in South Africa: Possible mechanism(s) of pathogenesis and pathophysiology of pansteatitis
- Association between advanced maternal age and maternal and neonatal morbidity: A cross-sectional study on a Spanish population
- Ethnic differences in the prevalence, socioeconomic and health related risk factors of knee pain and osteoarthritis symptoms in older Malaysians
- Increasing knowledge of HIV status in a country with high HIV testing coverage: Results from the Botswana Combination Prevention Project
- Friends with benefits: The effects of vegetative shading on plant survival in a green roof environment
- Comparison of the fecal, cecal, and mucus microbiome in male and female mice after TNBS-induced colitis
- Identifying candidate diagnostic markers for early stage of non-small cell lung cancer
- Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
- Correction: KML001 Induces Apoptosis and Autophagic Cell Death in Prostate Cancer Cells via Oxidative Stress Pathway
- Unique developmental trajectories of risk behaviors in adolescence and associated outcomes in young adulthood
- Enhanced fibrinolysis detection in a natural occurring canine model with intracavitary effusions: Comparison and degree of agreement between thromboelastometry and FDPs, D-dimer and fibrinogen concentrations
- Overexpression of Saussurea involucrata dehydrin gene SiDHN promotes cold and drought tolerance in transgenic tomato plants
- Foxtail millet (Setaria italica (L.) P. Beauv) CIPKs are responsive to ABA and abiotic stresses
- Autonomous drone hunter operating by deep learning and all-onboard computations in GPS-denied environments
- Heterogeneity Diffusion Imaging of gliomas: Initial experience and validation
- Frequency cluster formation and slow oscillations in neural populations with plasticity
- DHP23002 as a next generation oral paclitaxel formulation for pancreatic cancer therapy
- Diagnostic accuracy of SOX11 immunohistochemistry in mantle cell lymphoma: A meta-analysis
- Analytical solution to swing equations in power grids
- Pathways to conspiracy: The social and linguistic precursors of involvement in Reddit’s conspiracy theory forum
- Spatiotemporally random and diverse grid cell spike patterns contribute to the transformation of grid cell to place cell in a neural network model
- Empathic concern and personal distress depend on situational but not dispositional factors
- Who is more susceptible to job stressors and resources? Sensory-processing sensitivity as a personal resource and vulnerability factor
- Cost-effectiveness of integrating postpartum antiretroviral therapy and infant care into maternal & child health services in South Africa
- A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling
- One step at a time: Physical activity is linked to positive interpretations of ambiguity
- Calreticulin regulates vascular endothelial growth factor-A mRNA stability in gastric cancer cells
- Evaluation of various methods of selection of B. subtilis strains capable of secreting surface-active compounds
- Association between US Pharmacopeia (USP) monograph standards, generic entry and prescription drug costs
- Molecular characterisation of the synovial fluid microbiome in rheumatoid arthritis patients and healthy control subjects
- On sorption hysteresis in wood: Separating hysteresis in cell wall water and capillary water in the full moisture range
- Inbreeding, Allee effects and stochasticity might be sufficient to account for Neanderthal extinction
- Reliability and construct validity of the stepping-forward affordance perception test for fall risk assessment in community-dwelling older adults
- Socioeconomic determinants of nutritional status among ‘Baiga’ tribal children In Balaghat district of Madhya Pradesh: A qualitative study
- Study on characteristics of fire plume in building facade window under lateral blow
- ‘When you talk to someone in a bad way or always put her under pressure, it is actually worse than beating her’: Conceptions and experiences of emotional intimate partner violence in Rwanda and South Africa
- Effects of 6-mercaptopurine in pressure overload induced right heart failure
- The association between haemoglobin levels in the first 20 weeks of pregnancy and pregnancy outcomes
- Implementation and evaluation of an antimicrobial stewardship programme in companion animal clinics: A stepped-wedge design intervention study
- Factors associated with persistently high-cost health care utilization for musculoskeletal pain
- Nitrogen and chlorophyll status determination in durum wheat as influenced by fertilization and soil management: Preliminary results
- Effect of repeated in vivo microCT imaging on the properties of the mouse tibia
- Coupling environment and physiology to predict effects of climate change on the taxonomic and functional diversity of fish assemblages in the Murray-Darling Basin, Australia
- Hematology and plasma biochemistries in the Blanding’s turtle (Emydoidea blandingii) in Lake County, Illinois
- CRISPR-Cas influences the acquisition of antibiotic resistance in Klebsiella pneumoniae
- Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors
- Antidepressant prescriptions, discontinuation, depression and perinatal outcomes, including breastfeeding: A population cohort analysis
- Why men with a low-risk prostate cancer select and stay on active surveillance: A qualitative study
- Imported severe malaria and risk factors for intensive care: A single-centre retrospective analysis
- Combined treatment (image-guided thrombectomy and endovascular therapy with open femoral access) for acute lower limb ischemia: Clinical efficacy and outcomes
- Low-latency single channel real-time neural spike sorting system based on template matching
- Quantifying the scale effect in geospatial big data using semi-variograms
- Paper-and-pencil versus computerized administration mode: Comparison of data quality and risk behavior prevalence estimates in the European school Survey Project on Alcohol and other Drugs (ESPAD)
- Regression adjusted colocalisation colour mapping (RACC): A novel biological visual analysis method for qualitative colocalisation analysis of 3D fluorescence micrographs
- Ostrich eggshell bead diameter in the Holocene: Regional variation with the spread of herding in eastern and southern Africa
- Spatial and temporal variations in female size at maturity of a Southern Rock Lobster (Jasus edwardsii) population: A likely response to climate change
- Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells
- Training rhesus macaques to take daily oral antiretroviral therapy for preclinical evaluation of HIV prevention and treatment strategies
- Left ventricular structural and functional changes in Friedreich ataxia – Relationship with body size, sex, age and genetic severity
- Magnitude and factors associated with anemia among pregnant women attending antenatal care in Bench Maji, Keffa and Sheka zones of public hospitals, Southwest, Ethiopia, 2018: A cross -sectional study
- Effectiveness of telerehabilitation in the management of adults with stroke: A systematic review
- Hydrogen sulphide-induced hypometabolism in human-sized porcine kidneys
- Correction: Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin
- Retraction: Regulation of gastric smooth muscle contraction via Ca2+-dependent and Ca2+-independent actin polymerization
- Evaluation of neutral oral contrast agents for assessment of the small bowel at abdominal staging CT
- Blood type and breed-associated differences in cell marker expression on equine bone marrow-derived mesenchymal stem cells including major histocompatibility complex class II antigen expression
- Induced abortion and future use of IVF treatment; A nationwide register study
- Psychosocial determinants of sustained maternal functional impairment: Longitudinal findings from a pregnancy-birth cohort study in rural Pakistan
- Measurement of finger joint angle using stretchable carbon nanotube strain sensor
- Determinants of mortality among patients with drug-resistant tuberculosis in northern Nigeria
- Drugs modulating stochastic gene expression affect the erythroid differentiation process
- Efficacy of UB0316, a multi-strain probiotic formulation in patients with type 2 diabetes mellitus: A double blind, randomized, placebo controlled study
- Prognostic value of des-γ-carboxy prothrombin in patients with hepatocellular carcinoma treated with transarterial chemotherapy: A systematic review and meta-analysis
- Avermectin induces the oxidative stress, genotoxicity, and immunological responses in the Chinese Mitten Crab, Eriocheir sinensis
- Antibiotic use in mandarin production (Citrus reticulata Blanco) in major mandarin-producing areas in Thailand: A survey assessment
- Application of CPI cutoff value based on parentage testing of duos and trios typed by four autosomal kits
- Correction: Good and Bad in the Hands of Politicians: Spontaneous Gestures during Positive and Negative Speech
- Adolescents with worse levels of oral health literacy have more cavitated carious lesions
- Effective methods for the inactivation of Francisella tularensis
- Detection of early-stage Alzheimer’s pathology using blood-based autoantibody biomarkers in elderly hip fracture repair patients
- Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease
- Analysis of HER2 genomic binding in breast cancer cells identifies a global role in direct gene regulation
- Population productivity of shovelnose rays: Inferring the potential for recovery
- Correction: Long-term clinical outcomes in a cohort of patients with solitary plasmacytoma treated in the modern era
- Effects of tetracycline on myocardial infarct size in obese rats with chemically-induced colitis
- Mineral absorption is an enriched pathway in a brain region of restless legs syndrome patients with reduced MEIS1 expression
- Changes in weight and body composition across five years at university: A prospective observational study
- Adeno-associated virus-mediated expression of human butyrylcholinesterase to treat organophosphate poisoning
- Effects of insulin signaling on mouse taste cell proliferation
- Patient-level cost of home- and facility-based child pneumonia treatment in Suba Sub County, Kenya
- TAP: A static analysis model for PHP vulnerabilities based on token and deep learning technology
- Cost-effectiveness of QuantiFERON-TB Gold In-Tube versus tuberculin skin test for diagnosis and treatment of Latent Tuberculosis Infection in primary health care workers in Brazil
- Multifaceted intervention for the prevention and management of musculoskeletal pain in nursing staff: Results of a cluster randomized controlled trial
- Changes over time in creatinine clearance and comparison of emergent adverse events for HIV-positive adults receiving standard doses (300 mg/day) of lamivudine-containing antiretroviral therapy with baseline creatinine clearance of 30–49 vs ≥50 mL/min
- Population dynamics of foxes during restricted-area culling in Britain: Advancing understanding through state-space modelling of culling records
- Impacts of experimental advisory exit speed sign on traffic speeds for freeway exit ramp
- In-hospital outcomes and 30-day readmission rates among ischemic and hemorrhagic stroke patients with delirium
- Monitoring quality indicators for the Xpert MTB/RIF molecular assay in Ethiopia
- Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids
- Correction: Using remote sensing to detect whale strandings in remote areas: The case of sei whales mass mortality in Chilean Patagonia
- Comparison of the inoculum size effects of antibiotics on IMP-6 β-lactamase-producing Enterobacteriaceae co-harboring plasmid-mediated quinolone resistance genes
- Contrast-enhanced computed tomography findings of canine primary renal tumors including renal cell carcinoma, lymphoma, and hemangiosarcoma
- Non-invasive in vivo imaging of UCP1 expression in live mice via near-infrared fluorescent protein iRFP720
- Overexpression of pink1 or parkin in indirect flight muscles promotes mitochondrial proteostasis and extends lifespan in Drosophila melanogaster
- Fiber stiffness, pore size and adhesion control migratory phenotype of MDA-MB-231 cells in collagen gels
- Comparison of two experimental ARDS models in pigs using electrical impedance tomography
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- Stroke risks in women with dysmenorrhea by age and stroke subtype
- Changes in patterns of mortality rates and years of life lost due to firearms in the United States, 1999 to 2016: A joinpoint analysis
- In vitro modeling of Batrachochytrium dendrobatidis infection of the amphibian skin
- Development and validation of LC-MS/MS method for imatinib and norimatinib monitoring by finger-prick DBS in gastrointestinal stromal tumor patients
- Correction: Habitat disturbance and the organization of bacterial communities in Neotropical hematophagous arthropods
- Characterisation of early metazoan secretion through associated signal peptidase complex subunits, prohormone convertases and carboxypeptidases of the marine sponge (Amphimedon queenslandica)
- Time trends between 2002 and 2017 in correlates of self-reported sitting time in European adults
- Performance of patient acuity rating by rapid response team nurses for predicting short-term prognosis
- Changes in HbA1c during the first six years after the diagnosis of Type 2 diabetes mellitus predict long-term microvascular outcomes
- Correction: Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry
- Correction: Mental health and quality of life outcomes in family members of patients with chronic critical illness admitted to the intensive care units of two Brazilian hospitals serving the extremes of the socioeconomic spectrum
- Correction: Establishing an infrastructure for collaboration in primate cognition research
- Correction: The impact of public health insurance on health care utilisation, financial protection and health status in low- and middle-income countries: A systematic review
- Health provider and service-user experiences of sensory modulation rooms in an acute inpatient psychiatry setting
- Comparison of potential drug-drug interactions with metabolic syndrome medications detected by two databases
- The Polish version of the Cultural Intelligence Scale: Assessment of its reliability and validity among healthcare professionals and medical faculty students
- Selection of optimal reference genes for qRT-PCR analysis of shoot development and graviresponse in prostrate and erect chrysanthemums
- Metastasis risk prediction model in osteosarcoma using metabolic imaging phenotypes: A multivariable radiomics model
- Defining hospital community benefit activities using Delphi technique: A comparison between China and the United States
- Establishment of the experimental procedure for prediction of conjugation capacity in mutant UGT1A1
- A robust multi-objective optimization framework to capture both cellular and intercellular properties in cardiac cellular model tuning: Analyzing different regions of membrane resistance profile in parameter fitting
- Sea star wasting disease demography and etiology in the brooding sea star Leptasterias spp.
- Diagnostic plasma miRNA-profiles for ovarian cancer in patients with pelvic mass
- Genetic diversity and drug resistance of HIV-1 among infected pregnant women newly diagnosed in Luanda, Angola
- I’ve been robbed! – Can changes in floral traits discourage bee pollination?
- Visualising statistical models using dynamic nomograms
- Assessing the capacity of Malawi’s district and central hospitals to manage traumatic diaphyseal femoral fractures in adults
- Diagnostic performance of basal cortisol level at 0900-1300h in adrenal insufficiency
- The Mastery Rubric for Bioinformatics: A tool to support design and evaluation of career-spanning education and training
- Microdissection and whole chromosome painting confirm karyotype transformation in cryptic species of the Lariophagus distinguendus (Förster, 1841) complex (Hymenoptera: Pteromalidae)
- Quality of Kangaroo Mother Care services in Ethiopia: Implications for policy and practice
- Gemcitabine potentiates the anti-tumour effect of radiation on medullary thyroid cancer
- iTRAQ-based high-throughput proteomics analysis reveals alterations of plasma proteins in patients infected with human bocavirus
- The detection of a non-anemophilous plant species using airborne eDNA
- Perception and control of low cable operation forces in voluntary closing body-powered upper-limb prostheses
- Neoadjuvant chemotherapy plus surgery versus concurrent chemoradiotherapy in stage IB2-IIB cervical cancer: A systematic review and meta-analysis
- Randomized methods to characterize large-scale vortical flow networks
- Disentangling the coexistence strategies of mud-daubing wasp species through trophic analysis in oases of Baja California peninsula
- Front-of-pack nutritional labels: Understanding by low- and middle-income Mexican consumers
- Distress in patients with end-stage renal disease: Staff perceptions of barriers to the identification of mild-moderate distress and the provision of emotional support
- Pathways to antibiotics in Bangladesh: A qualitative study investigating how and when households access medicine including antibiotics for humans or animals when they are ill
- DOC export is exceeded by C fixation in May Creek: A late-successional watershed of the Copper River Basin, Alaska
- Behavioral observation of prosocial behavior and social initiative is related to preschoolers’ psychopathological symptoms
- Evaluating the impact of citations of articles based on knowledge flow patterns hidden in the citations
- Correction: Economic sanctions and academia: Overlooked impact and long-term consequences
- Correction: A novel association between relaxin receptor polymorphism and hematopoietic stem cell yield after mobilization
- Expression of Concern: Cooperativity of Oncogenic K-Ras and Downregulated p16/INK4A in Human Pancreatic Tumorigenesis
- Price dispersion of generic medications
- Sex differences in body composition but not neuromuscular function following long-term, doxycycline-induced reduction in circulating levels of myostatin in mice
- The emotion regulation effect of cognitive control is related to depressive state through the mediation of rumination: An ERP study
- Comparison of SMS-EPI and 3D-EPI at 7T in an fMRI localizer study with matched spatiotemporal resolution and homogenized excitation profiles
- Left ventricular mass normalization for body size in children based on an allometrically adjusted ratio is as accurate as normalization based on the centile curves method
- Correction: Combining biophysical parameters, spectral indices and multivariate hyperspectral models for estimating yield and water productivity of spring wheat across different agronomic practices
- Correction: Flowers as viral hot spots: Honey bees (Apis mellifera) unevenly deposit viruses across plant species
- 'Small small quarrels bring about happiness or love in the relationships’: Exploring community perceptions and gendered norms contributing to male perpetrated intimate partner violence in the Central Region of Ghana
- The performance of practitioners conducting facial comparisons on images of children across age
- Increased amounts and stability of telomeric repeat-containing RNA (TERRA) following DNA damage induced by etoposide
- Patients with limitation or withdrawal of life supporting care admitted in a medico-surgical intermediate care unit: Prevalence, description and outcome over a six-month period
- Correction: Diverse radiofrequency sensitivity and radiofrequency effects of mobile or cordless phone near fields exposure in Drosophila melanogaster
- Predicting the performance of TV series through textual and network analysis: The case of Big Bang Theory
- Risk of temperature, humidity and concentrations of air pollutants on the hospitalization of AECOPD
- Mixed methods grant applications in the health sciences: An analysis of reviewer comments
- Renal abnormalities among children with sickle cell conditions in highly resource-limited setting in Ghana
- Size matters: How reaching and vergence movements are influenced by the familiar size of stereoscopically presented objects
- Willingness to receive institutional and community-based eldercare among the rural elderly in China
- An improved deep learning method for predicting DNA-binding proteins based on contextual features in amino acid sequences
- Beyond executive functions, creativity skills benefit academic outcomes: Insights from Montessori education
- A LAMP assay for the rapid and robust assessment of Wolbachia infection in Aedes aegypti under field and laboratory conditions
- Nonarteritic anterior ischemic optic neuropathy is associated with cerebral small vessel disease
- Fiber-tract localized diffusion coefficients highlight patterns of white matter disruption induced by proximity to glioma
- The fight against polio through the NO-DO newsreels during the Francoism period in Spain
- Ocean sound levels in the northeast Pacific recorded from an autonomous underwater glider
- Cost-consequence analysis of influenza vaccination among the staff of a large teaching hospital in Rome, Italy: A pilot study
- The relationship among the progression of inflammation in umbilical cord, fetal inflammatory response, early-onset neonatal sepsis, and chorioamnionitis
- How medical professional students view older people with dementia: Implications for education and practice
- An enhanced nonparametric EWMA sign control chart using sequential mechanism
- Land use change, carbon stocks and tree species diversity in green spaces of a secondary city in Myanmar, Pyin Oo Lwin
- Is there a difference in women’s experiences of care with medication vs. manual vacuum aspiration abortions? Determinants of person-centered care for abortion services
- Maternal complications in pregnancy and childbirth for women with epilepsy: Time trends in a nationwide cohort
- Adsorption of oxytetracycline on kaolinite
- Interdisciplinary stratified care for low back pain: A qualitative study on the acceptability, potential facilitators and barriers to implementation
- The role of resource transfer in positive, non-additive litter decomposition
- The impact of language on the interpretation of resuscitation clinical care plans by doctors. A mixed methods study
- Quantum dots reveal heterogeneous membrane diffusivity and dynamic surface density polarization of dopamine transporter
- Genomic analysis of Shiga toxin-producing Escherichia coli from patients and asymptomatic food handlers in Japan
- The heavy metals lead and cadmium are cytotoxic to human bone osteoblasts via induction of redox stress
- Anatomical, taxonomic, and phylogenetic reappraisal of a poorly known ghost knifefish, Tembeassu marauna (Ostariophysi: Gymnotiformes), using X-ray microcomputed tomography
- Matrix-assisted laser desorption/ionization time of flight mass spectrometry identification of Vibrio (Listonella) anguillarum isolated from sea bass and sea bream
- Recommendations of older adults on how to use the PROM ‘TOPICS-MDS’ in healthcare conversations: A Delphi study
- The winner takes it all—Competitiveness of single nodes in globalized supply networks
- Hamsters in the city: A study on the behaviour of a population of common hamsters (Cricetus cricetus) in urban environment
- Correction: Liquid biopsies for omics-based analysis in sentinel mussels
- Size matters! Association between journal size and longitudinal variability of the Journal Impact Factor
- Drug resistance and epidemiology characteristics of multidrug-resistant tuberculosis patients in 17 provinces of China
- A model-based framework for chronic hepatitis C prevalence estimation
- Adding rewards to regulation: The impacts of watershed conservation on land cover and household wellbeing in Moyobamba, Peru
- Clinical determinants of social media use in individuals with schizophrenia
- Arsenic and nutrient absorption characteristics and antioxidant response in different leaves of two ryegrass (Lolium perenne) species under arsenic stress
- An evolution of socioeconomic related inequality in teenage pregnancy and childbearing in Malawi
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