Incidence of colorectal cancer in Eritrea: Data from the National Health Laboratory, 2011-2017


Autoři: Lidia Biniam Medhin aff001;  Oliver Okoth Achila aff002;  Adiam Tesfamariam Abrham aff002;  Biniam Efrem aff002;  Kibrom Hailu aff001;  Daniel Mebrahtu Abraha aff003;  Luwam Gilazghi aff004;  Alay Meresie aff005;  Salih Mohammed Said aff006
Působiště autorů: Pathology, National Health Laboratory, Asmara, Eritrea aff001;  Clinical Laboratory Sciences, Orotta School of Medicine and Health Sciences, Asmara, Eritrea aff002;  Hematology, National Health Laboratory, Asmara, Eritrea aff003;  Immunoserology, National Health Laboratory, Asmara, Eritrea aff004;  Clinical Chemistry, National Health Laboratory, Asmara, Eritrea aff005;  Microbiology, National Health Laboratory, Asmara, Eritrea aff006
Vyšlo v časopise: PLoS ONE 14(11)
Kategorie: Research Article
doi: 10.1371/journal.pone.0224045

Souhrn

Introduction

Recent studies have reported a significant increase in the prevalence of colorectal cancer (CRC) in Sub-Saharan Africa (SSA). Further, several studies employing disparate modelling algorithms have projected a significant rise in the frequency of CRC cases in the region. However, lack of good quality data on multiple themes related to CRC including incidence, among others, continues to be a problem in the region. Therefore, this study was designed to collect data on the incidence of CRC in Eritrea.

Methods

We conducted a retrospective analysis using data captured between 2011 and 2017 at the National Health Laboratory (NHL) in Asmara, Eritrea.

Results

241 colorectal cases were identified in the Eritrean National Health Laboratory (NHL) database between 2011 and 2017. In the final analysis we included 94 patients confirmed cases giving an average of 18.8 patients per annum. The average age ± Standard deviation (SD) was 57.62 ± 17.14 with a male: female ratio of 58/36 (1: 1.61). The minimum and maximum age of the patients was 19 and 90 years, respectively. The rectum to colon ratio was 47/47 (1:1). The proportion of patients < 50 years in this cohort was significant. The age-standardized incidence rate (ASIR) in the study period was between 0.97 per 100 000 to 2.21 per 100 000. Similarly, the cumulative ASIR was 9.97 per 100 000. Analysis of trends did not reveal shifts over the study period (P<0.05). However, a strong correlation between incidence and age was established.

Conclusion

This study suggests that the incidence of CRC in Eritrea is relatively low. A significant number of patients were less than 50 years of age. Even then it’s our opinion that this study may underestimate the incidence of CRC.

Klíčová slova:

Africa – Age groups – Colon – Colorectal cancer – Malignant tumors – Public and occupational health – Rectum – Eritrea


Zdroje

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Článek vyšel v časopise

PLOS One


2019 Číslo 11