The association between caesarean section delivery and later life obesity in 21-24 year olds in an Urban South African birth cohort


Autoři: Eniola Sogunle aff001;  Gwinyai Masukume aff001;  Gill Nelson aff001
Působiště autorů: School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa aff001
Vyšlo v časopise: PLoS ONE 14(11)
Kategorie: Research Article
doi: 10.1371/journal.pone.0221379

Souhrn

Background

Obesity is an important public health problem and rates have reached epidemic proportions in many countries. Studies have explored the association between infants delivered by caesarean section and their later life risk of obesity, in many countries outside Africa. As a result of the increasing caesarean section and obesity rates in South Africa, we investigated the association in this country.

Methods

This was a retrospective analysis of data that were collected from a prospective South African birth cohort (Birth to Twenty Plus), established in 1990. A total of 889 young adults aged 21–24 years were included in the analysis. Poisson regression models were fitted to assess the association between mode of delivery and early adulthood obesity.

Results

Of the 889 young adults, 106 (11.9%) were obese while 72 (8.1%) were delivered by caesarean section; of which 14 (19.4%) were obese. Caesarean section delivery was significantly associated with obesity in young adults after adjusting for potential confounders like young adults’ sex and birth weight, mothers’ parity, and education (incidence rate ratio 1.64, 95% CI 1.01–2.68, p = 0.045).

Conclusion

The association of caesarean section with early adulthood obesity should be interpreted with caution because data on certain key confounding factors such as mothers’ pre-pregnancy body mass index and gestational diabetes were not available. Further research from Africa, with larger sample sizes and databases with useful linking of maternal and infant data, should be conducted.

Klíčová slova:

Birth weight – Body Mass Index – Cohort studies – Infants – Labor and delivery – Obesity – Young adults


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2019 Číslo 11