#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Effects of virtual reality rehabilitation training on gait and balance in patients with Parkinson's disease: A systematic review


Autoři: Cheng Lei aff001;  Kejimu Sunzi aff001;  Fengling Dai aff002;  Xiaoqin Liu aff001;  Yanfen Wang aff001;  Baolu Zhang aff002;  Lin He aff001;  Mei Ju aff002
Působiště autorů: Department of Nursing, People’s Hospital of Deyang, Deyang, Sichuan, China aff001;  School of Nursing, Southwest Medical University, Luzhou, Sichuan, China aff002;  Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand aff003
Vyšlo v časopise: PLoS ONE 14(11)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0224819

Souhrn

Objective

In recent years, virtual reality (VR) has been tested as a therapeutic tool in neurorehabilitation research. However, the impact effectiveness of VR technology on for Parkinson’s Disease (PD) patients is still remains controversial unclear. In order to provide a more scientific basis for rehabilitation of PD patients’ modality, we conducted a systematic review of VR rehabilitation training for PD patients and focused on the improvement of gait and balance.

Methods

An comprehensive search was conducted using the following databases: PubMed, Web of Science, Cochrane Library, CINHAL, Embase and CNKI (China National Knowledge Infrastructure).Articles published before 30 December 2018 and of a randomized controlled trial design to study the effects of VR for patients with PD were included. The study data were pooled and a meta-analysis was completed. This systematic review was conducted in accordance with the PRISMA guideline statement and was registered in the PROSPERO database (CRD42018110264).

Results

A total of sixteen articles involving 555 participants with PD were included in our analysis. VR rehabilitation training performed better than conventional or traditional rehabilitation training in three aspects: step and stride length (SMD = 0.72, 95%CI = 0.40,1.04, Z = 4.38, P<0.01), balance function (SMD = 0.22, 95%CI = 0.01,0.42, Z = 2.09, P = 0.037), and mobility(MD = -1.95, 95%CI = -2.81,-1.08, Z = 4.41, P<0.01). There was no effect on the dynamic gait index (SMD = -0.15, 95%CI = -0.50,0.19, Z = 0.86, P = 0.387), and gait speed (SMD = 0.19, 95%CI = -0.03,0.40, Z = 1.71, P = 0.088).As for the secondary outcomes, compared with the control group, VR rehabilitation training demonstrated more significant effects on the improvement of quality of life (SMD = -0.47, 95%CI = -0.73,-0.22, Z = 3.64, P<0.01), level of confidence (SMD = -0.73, 95%CI = -1.43,-0.03, Z = 2.05, P = 0.040), and neuropsychiatric symptoms (SMD = -0.96, 95%CI = -1.27,-0.65, Z = 6.07, P<0.01), while it may have similar effects on global motor function (SMD = -0.50, 95%CI = -1.48,0.48, Z = 0.99, P = 0.32), activities of daily living (SMD = 0.25, 95%CI = -0.14,0.64, Z = 1.24, P = 0.216), and cognitive function (SMD = 0.21, 95%CI = -0.28,0.69, Z = 0.84, P = 0.399).During the included interventions, four patients developed mild dizziness and one patient developed severe dizziness and vomiting.

Conclusions

According to the results of this study, we found that VR rehabilitation training can not only achieve the same effect as conventional rehabilitation training. Moreover, it has better performance on gait and balance in patients with PD. Taken together, when the effect of traditional rehabilitation training on gait and balance of PD patients is not good enough, we believe that VR rehabilitation training can at least be used as an alternative therapy. More rigorous design of large-sample, multicenter randomized controlled trials are needed to provide a stronger evidence-based basis for verifying its potential advantages.

Klíčová slova:

Activities of daily living – Balance and falls – Gait rehabilitation – Neurorehabilitation – Parkinson disease – Quality of life – Systematic reviews – Virtual reality


Zdroje

1. Canning CG, Paul SS, Alice N. Prevention of falls in Parkinson's disease: a review of fall risk factors and the role of physical interventions. Neurodegener Dis Manag. 2014; 3: 203–221.

2. Jankovic J. Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry. 2008; 4: 368–376.

3. Nerius M, Fink A, Doblhammer G. Parkinson's disease in Germany: prevalence and incidence based on health claims data. Acta Neurol Scand. 2017; 5: 386–392.

4. Rizos A, Martinezmartin P, Odin P, Antonini A, Kessel B, Kozul TK,et al. Characterizing motor and non-motor aspects of early-morning off periods in Parkinson's disease: An international multicenter study. Parkinsonism Relat Disord. 2014; 11: 1231–1235.

5. Tomlinson CL, Patel S, Meek C, Clarke CE, Stowe R, Shah L, et al. Physiotherapy versus placebo or no intervention in Parkinson's disease.Cochrane Database Syst Rev.2013;9:CD002817

6. Fox SH, Regina K, Shen-Yang L, Bernard R, Klaus S, Miguel C, et al. The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the motor symptoms of Parkinson's disease. Mov Disord. 2011; S3: S2–S41.

7. Baizabalcarvallo J F, Jankovic J. Movement disorders induced by deep brain stimulation. Parkinsonism Relat Disord, 2016; 25:1–9. doi: 10.1016/j.parkreldis.2016.01.014 26806438

8. Corcos DM, Robichaud JA, David FJ, Leurgans SE, Vaillancourt DE, Cynthia P, et al. A two-year randomized controlled trial of progressive resistance exercise for Parkinson's disease. Mov Disord. 2013; 9: 1230–1240.

9. David FJ, Robichaud JA, Leurgans SE, Poon C, Kohrt WM, Goldman JG, et al. Exercise improves cognition in Parkinson's disease: The PRET‐PD randomized, clinical trial. Mov Disord. 2015; 12: 1657–1663.

10. Beibei L, Qinneng D, Wusheng Z. Research progress on the role of virtual reality technology in rehabilitation of nervous system diseases. Chin J Contemp Neurol Neurosurg. 2018; 03: 222–225.

11. Gallagher R, Damodaran H, Werner WG, Powell W, Deutsch JE. Auditory and visual cueing modulate cycling speed of older adults and persons with Parkinson’s disease in a Virtual Cycling (V-Cycle) system. J Neuroeng Rehabil. 2016; 1: 77.

12. Benito PAM, Ana RG, Ángel G, Alberto BS, Beatriz PA, Ana Isabel PAG. Application of virtual reality in the motor aspects of neurorehabilitation. Rev Neurologia. 2010; 8: 481–488.

13. Iruthayarajah J, Mcintyre A, Cotoi A, Macaluso S, Teasell R. The use of virtual reality for balance among individuals with chronic stroke: a systematic review and meta-analysis. Top Stroke Rehabil. 2016; 1: 68–79.

14. Donath L, Rössler R, Faude O. Effects of Virtual Reality Training (Exergaming) Compared to Alternative Exercise Training and Passive Control on Standing Balance and Functional Mobility in Healthy Community-Dwelling Seniors: A Meta-Analytical Review. Sports Med. 2016; 9: 1–17.

15. Xiaoxiao W, HongWei D, Hang L, AiHong W. Effects of Virtual Reality on Balance and Activities of Daily Living in Patients with Parkinson's Disease: A Meta-Analysis. Chin J Rehabil Theory Pract. 2017; 12: 1443–1449.

16. Dockx K, Bekkers EM, Van DBV, Ginis P, Rochester L, Hausdorff JM, et al. Virtual reality for rehabilitation in Parkinson's disease. Cochrane Database Syst Rev. 2013; 8: D10760.

17. Wenchieh Y, Hsingkuo W, Rueymeei W, Chienshun L, Kwanhwa L. Home-based virtual reality balance training and conventional balance training in Parkinson's disease: A randomized controlled trial. J Formos Med Assoc. 2016; 9: 734–743.

18. Ribas CG, Alves Da Silva L, Corrêa MR, Teive HG, Valderramas S. Effectiveness of exergaming in improving functional balance, fatigue and quality of life in Parkinson's disease: A pilot randomized controlled trial. Parkinsonism Relat Disord. 2017: 13–18.

19. Alves MLM, Mesquita BS, Morais WS, Leal JC, Satler CE, Dos Santos Mendes FA. Nintendo Wii™ Versus Xbox Kinect™ for Assisting People With Parkinson's Disease. Percept Mot Skills. 2018; 3: 546–565.

20. Si C, Jie L, Shun L, Kai W, Yugong H. Effects of Virtual Reality Rehabilitation on Balance for Patients with Parkinson's Disease. Chin J Rehabil Theory Pract. 2017; 09: 1091–1095.

21. Pompeu JE, Mendes FADS, Silva KGD, Lobo AM, Oliveira TDP, Zomignani AP, et al. Effect of Nintendo Wii™-based motor and cognitive training on activities of daily living in patients with Parkinson's disease: A randomised clinical trial. Physiotherapy. 2012; 3: 196–204.

22. Yingyi L, Yearu Y, Shihjung C, Yihru W, Jongling F, Rayyau W. Virtual Reality–Based Training to Improve Obstacle-Crossing Performance and Dynamic Balance in Patients With Parkinson’s Disease. Neurorehab Neural Re. 2015; 7: 658–667.

23. Mengche S, Rayyau W, Shihjung C, Yearu Y. Effects of a balance-based exergaming intervention using the Kinect sensor on posture stability in individuals with Parkinson’s disease: a single-blinded randomized controlled trial. J Neuroeng Rehabil. 2016; 1: 78.

24. Namyong L, Dongkyu L, Hyunseung S. Effect of virtual reality dance exercise on the balance, activities of daily living, and depressive disorder status of Parkinson's disease patients. J Phys Ther Sci. 2015; 1: 145–147.

25. van den Heuvel MC, Kwakkel G, Beek PJ, Berendse HW, Daffertshofer A, van Wegen EEH. Effects of augmented visual feedback during balance training in Parkinson's disease: A pilot randomized clinical trial. Parkinsonism Relat Disord. 2014; 12: 1352–1358.

26. Shen X, Mak MK. Balance and Gait Training With Augmented Feedback Improves Balance Confidence in People With Parkinson's Disease: A Randomized Controlled Trial. Neurorehabil Neural Repair. 2014; 6: 524–535.

27. Ferraz DD, Trippo KV, Duarte GP, Neto MG, Bernardes Santos KO, Filho JO. The Effects of Functional Training, Bicycle Exercise, and Exergaming on Walking Capacity of Elderly Patients With Parkinson Disease: A Pilot Randomized Controlled Single-blinded Trial. Arch Phys Med Rehabil. 2018; 5: 826–833.

28. Gandolfi M, Geroin C, Dimitrova E, Boldrini P, Waldner A, Bonadiman S, et al. Virtual Reality Telerehabilitation for Postural Instability in Parkinson’s Disease: A Multicenter, Single-Blind, Randomized, Controlled Trial. Biomed Res Int. 2017: 1–11.

29. Zhicheng L, Azheng C, Yijing J, Dengzhong C, Xiaoqian Y, Yongmei Y. Effects of Virtual Reality Balance Game on Balance Function for Parkinson's Disease. Chin J Rehabil Theory Pract. 2016; 09: 1059–1063.

30. Özgönenel L, Cagirici S, Cabalar M, Durmusoglu G. Use of Game Console for Rehabilitation of Parkinson's Disease. Balk Med J. 2016; 4: 396–400.

31. Pedreira G, Prazeres A, Cruz D, Gomes I, Monteiro L, Melo A. Virtual games and quality of life in Parkinson’s disease: A randomised controlled trial. Adv Parkinson's Dis. 2013; 04: 97–101.

32. Changyi Y, Kwanhwa L, Minghsia H, Rueymeei W, Tungwu L, Chiahwa L. Effects of virtual reality-augmented balance training on sensory organization and attentional demand for postural control in people with Parkinson disease: a randomized controlled trial. Phys Ther. 2011; 6: 862–874.

33. Pan X, Hamilton A. Why and how to use virtual reality to study human social interaction: The challenges of exploring a new research landscape. Br J Psychol. 2018; 3: 395–417.

34. Feng Z, Gonzalez V, Amor R, Lovreglio R, Cabrera G. Immersive Virtual Reality Serious Games for Evacuation Training and Research: A Systematic Literature Review. Comput Educ. 2018: 252–266.

35. Freeman D, Haselton P, Freeman J, Spanlang B, Kishore S, Albery E, et al. Automated psychological therapy using immersive virtual reality for treatment of fear of heights: a single-blind, parallel-group, randomised controlled trial. Lancet Psychiat. 2018; 8: 625–632.

36. Reger GM, Smolenski D, Norr A, Katz A, Buck B, Rothbaum BO. Does Virtual Reality Increase Emotional Engagement During Exposure for PTSD? Subjective Distress During Prolonged and Virtual Reality Exposure Therapy. J Anxiety Disord. 2019;1: 75–81.

37. Sampson P, Freeman C, Coote S, Demain S, Feys P, Meadmore K, et al. Using Functional Electrical Stimulation Mediated by Iterative Learning Control and Robotics to Improve Arm Movement for People With Multiple Sclerosis. IEEE Trans Neural Syst Rehabil Eng. 2015; 99: 235–248.

38. Mahajan HP, Spaeth DM, Dicianno BE, Brown K, Cooper RA. Preliminary evaluation of variable compliance joystick for people with multiple sclerosis. J Rehabil Res Dev. 2014; 6: 951–962.

39. Darya Y, Gago MF, Estela B, Vítor F, Gago NF, Luís C, et al. Compensatory postural adjustments in Parkinson's disease assessed via a virtual reality environment. Behav Brain Res. 2016: 384–392.

40. Zhen L, Xiuguo H, Jing S, Shaojun M. Virtual reality for improving balance in patients after stroke: A systematic review and meta-analysis. Clin Rehabil. 2016; 5: 432–440.

41. Coyle H, Traynor V, Solowij N. Computerized and Virtual Reality Cognitive Training for Individuals at High Risk of Cognitive Decline: Systematic Review of the Literature. Am J Geriatr Psychiatry. 2015; 4: 335–359.

42. Ying W, Hua P, Fan J, Na C, Lei Z, Shuo Y. Analysis of tremor characteristics in patients with Parkinson's disease in different stages. Chin J Neuroimmunol & Neurol, 2017;1:25–28 doi: 10.1016/j.jneuroim.2014.04.012

43. Rose T, Chang SN, Chen KB. Immersion of virtual reality for rehabilitation—Review. Appl Ergon. 2018;5:153–161.

44. Benoit M, Guerchouche R, Petit PD, Chapoulie E, Manera V, Chaurasia G, et al. Is it possible to use highly realistic virtual reality in the elderly? A feasibility study with image-based rendering. Neuropsych Dis Treat. 2015; 3: 557–563.


Článek vyšel v časopise

PLOS One


2019 Číslo 11
Nejčtenější tento týden
Nejčtenější v tomto čísle
Kurzy

Zvyšte si kvalifikaci online z pohodlí domova

KOST
Koncepce osteologické péče pro gynekology a praktické lékaře
nový kurz
Autoři: MUDr. František Šenk

Sekvenční léčba schizofrenie
Autoři: MUDr. Jana Hořínková

Hypertenze a hypercholesterolémie – synergický efekt léčby
Autoři: prof. MUDr. Hana Rosolová, DrSc.

Svět praktické medicíny 5/2023 (znalostní test z časopisu)

Imunopatologie? … a co my s tím???
Autoři: doc. MUDr. Helena Lahoda Brodská, Ph.D.

Všechny kurzy
Kurzy Podcasty Doporučená témata Časopisy
Přihlášení
Zapomenuté heslo

Zadejte e-mailovou adresu, se kterou jste vytvářel(a) účet, budou Vám na ni zaslány informace k nastavení nového hesla.

Přihlášení

Nemáte účet?  Registrujte se

#ADS_BOTTOM_SCRIPTS#