Retrospective comparative analysis of intraocular lens calculation formulas after hyperopic refractive surgery

Autoři: Anibal Francone aff001;  Nicole Lemanski aff002;  Martin Charles aff001;  Sheila Borboli-Gerogiannis aff002;  Sherleen Chen aff002;  Marie-Claude Robert aff002;  Roberto Pineda, II aff002
Působiště autorů: Centro Oftalmológico Dr. Charles Sociedad Anónima, Buenos Aires, Argentina aff001;  Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States of America aff002
Vyšlo v časopise: PLoS ONE 14(11)
Kategorie: Research Article
doi: 10.1371/journal.pone.0224981



To compare the intraocular lens calculation formulas and evaluate postoperative refractive results of patients with previous hyperopic corneal refractive surgery.


Retrospective, comparative, observational study.


Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.


Clinical charts and optical biometric data of 39 eyes from 24 consecutive patients diagnosed with previous hyperopic laser vision correction and cataract surgery were reviewed and analyzed. The Intraocular lens (IOL) power calculation using the Holladay 2 formula (Lenstar) and the American Society of Cataract and Refractive Surgery (ASCRS) Post-Refractive IOL Calculator (version 4.9, 2017) were compared to the actual manifest refractive spherical equivalent (MRSE) following cataract surgery. No pre-Lasik / PRK or post-Lasik / PRK information was used in any of the calculations. The IOL prediction error, the mean IOL prediction error, the median absolute refractive prediction error, and the percentages of eyes within ±0.50 diopter (D) and ±1.00 D of the predicted refraction were calculated.


The Holladay 2 formula produced a mean arithmetic IOL prediction error significantly different from zero (P = 0.003). Surprisingly, the mean arithmetic IOL prediction errors generated by Shammas, Haigis-L and Barret True K No History formulas were not significantly different from zero (P = 0.14, P = 0.49, P = 0.81, respectively).There were no significant differences in the median absolute refractive prediction error or percentage of eyes within ± 0.50 D or ± 1.00 D of the predicted refraction between formulas or methods.


In eyes with previous hyperopic LASIK/PRK and no prior data, there were no significant differences in the accuracy of IOL power calculation between the Holladay 2 formula and the ASCRS Post-refractive IOL calculator.

Klíčová slova:

Arithmetic – Cataract surgery – Cornea – Eye lens – Eyes – Photorefractive keratectomy – Refractive surgery – LASIK


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