Cyclic loading test study on a new cast-in-situ insulated sandwich concrete wall
Authors:
Wentao Qiao aff001; Xiaoxiang Yin aff001; Shengying Zhao aff003; Dong Wang aff004
Authors place of work:
School of Civil Engineering, Shi Jiazhuang Tiedao University, Shi Jiazhuang, China
aff001; Cooperative Innovation Center of Disaster Prevention and Mitigation for Large Infrastructure in Hebei Province (Shi Jiazhuang Tiedao University), Shi Jiazhuang, China
aff002; School of Civil Engineering, Harbin Institute of Technology, Harbin, China
aff003; TRC Companies, Baton Rouge, United States of America
aff004
Published in the journal:
PLoS ONE 14(11)
Category:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0225055
Summary
Insulated sandwich concrete panel (ISCP) is widely used because of its high thermal insulation efficiency and low construction cost. Aiming at improving traditional ISCP, a new cast-in-situ concrete wall structure made of ISCP is proposed, which is composed of thin-walled cold-formed steels, slant steel wire connectors, steel wire meshes, concrete layers, expanded polystyrene sheets and reinforced concrete embedded columns. In order to assess the hysteretic properties of the new insulated sandwich concrete wall and the influence of various parameters, low-frequency horizontal cyclic load tests were carried out on seven full-scale specimens of new type cast-in-situ insulated sandwich concrete wall. The specimens were compared and analyzed with respect to failure mode, bearing capacity, ductility, degradation characteristics and energy dissipation capacity. The results show that the final failure pattern of the specimen is two main diagonal cracks intersecting each other; the bearing capacity is greatly affected by concrete thickness and axial compression ratio, regardless of concrete strength. Brittle failure is typically observed when the steel wire spacing is large, while ductility is pronounced when the concrete layer thickness is small and the concrete strength is low; the smaller the thickness of concrete layer, the faster the stiffness degrades. The wall structure shows a better energy dissipation performance with a smaller steel wire spacing, lower concrete strength and smaller axial compression ratio.
Keywords:
Steel – Built structures – Stiffness – Deformation – compression – Composite materials – Polystyrene – Concrete
Introduction
Nowadays, environmental protection and sustainable development are hot issues of global concern. In the architectural field, more and more scholars focus on the study of energy-saving buildings. Insulated sandwich concrete panel (ISCP) is representative of an energy-saving building, which is typically composed of concrete layers on both sides, insulation layers in between, and shear connectors. The main advantages of this panel are: (i) ease of erection at reasonable costs, (ii) high efficiency of thermal and sound insulation, and (iii) flexibility in utility, either as enveloping elements or as load-bearing components.
To date, research on ISCP mainly focuses on efficiency of thermal insulation, composite action, materials and constructions and structural performance.
In terms of insulation efficiency, how to reduce the influence of cold bridge effect is mainly considered. Currently, the most popular method is to make shear connectors with materials with low thermal efficiency. For instance, a new type of hybrid connector wrapped with nylon was proposed to improve the thermal performance of ISCP wall [1]. Other commonly used materials with low thermal efficiency include fiber-reinforced polymer (FRP), carbon-fiber-reinforced polymer (CFRP), and glass-fiber-reinforced polymer (GFRP).
In terms of composite action, ISCP are usually categorized into non-composite (NC), partially composite (PC) and fully composite (FC) according to the degree of composite action (i.e., the amount of longitudinal shear transfer between concrete layers through the insulation layer). It is generally believed that the composite action of ISCP is mainly provided via shear connectors, and studies indicate that connectors’ dimension and spacing greatly affect composite action, and that connectors inserted at an angle other than 90° are considerably stronger than those inserted perpendicularly [2]. Most studies on composite action are considered from the flexural response and shear response [3–6].
In terms of materials and constructions, many researchers proposed different forms of materials and constructions. The changes of materials and constructions for better mechanical performance, higher insulation efficiency and easier construction, but they often restrict each other in practice. In order to make the construction operation easier, the sandwich concrete panel without shear connector was proposed [7,8], and textile reinforced concrete (TRC) layer was adopted, but its bearing capacity was too low. In order to improve bearing capacity, Xie Qun et al. adopted the reinforced concrete core column, and bearing capacity has been effectively improved [9]. Thomas G. Norris et al. tried to improve the performance of sandwich concrete panel by using the function of restrained concrete, but its construction form was too complex, which was inconvenient for construction [10]. In addition, some researchers have focused on shear connectors to improve the performance of sandwich concrete panels by changing the materials of the connectors [11–13], shape and layout [14–16]. These structures are very novel, but they are very complicated to manufacture and cost a lot. Some other studies focus on non-load-bearing components and use textile reinforced reactive powder concrete (TRRPC) as the vertical panel and GFRP as the connectors, which improves the cracking and insulation performance of the sandwich concrete panel [17,18]. A lot of bending, shearing and axial compression tests have been carried out in the above aspects of research. However, there are few studies on the seismic behavior of ISCP. Studies have shown that the seismic performance of ISCP is comparable with those of common reinforced concrete panels [19,20]. Moreover, according to the results of the shaking table test, the stiffness and strength of ISCP structure under the action of dynamic excitation are better than the previous results of the quasi-static cycle test of a single specimen [21]. In addition, ISCP also shows good performance when it is used for filling walls [22] and prefabricated components [23]. Even under the explosion load, ICSP wall shows a stronger ability to absorb and dissipate the explosion energy and has a better anti-crushing stability [24].
Existing insulated sandwich concrete structure systems often lead to the cold bridge effect due to the discontinuity of the insulation layer at the joints of walls, and most of the joints are complex in composition and inconvenient in construction. Although the thermal efficiency problem can be solved by using FRP connectors, FRP connectors are prone to brittle fracture and be pulled-out, and the cost is high [3,12]. In order to solve the problems above, this paper proposes a new type of cast-in-situ insulated sandwich concrete wall structure by adding thin-walled cold-formed steels, reinforced concrete embedded columns and changing the layout of connectors based on traditional ISCP. The structure is composed of thin-walled cold-formed steels, slant steel wire connectors, steel wire meshes, concrete layers, expanded polystyrene sheets and reinforced concrete embedded columns, which has been significantly improved in terms of thermal insulation efficiency, structural optimization and cost control. Main features of this novel structure are:
All the walls are sandwich walls, composed of three-dimensional steel wire skeletons, expanded polystyrene sheets, concrete and thin-walled cold-formed steels.
The two concrete layers of the wall are connected by slant steel wires used as shear connectors. The angle between the slant steel wire and the wall is 72°, and the layout spacing is 50 mm. The wall belongs to partially composite sandwich structure.
The thickness of concrete layers on both sides is identical, as is the ratio of horizontal and vertical reinforcement.
In the openings, centers and edges of the sandwich walls, closed frames are formed by horizontally and vertically welding thin-walled cold-formed steels with rectangular sections.
The walls are connected by reinforced concrete embedded columns and additional reinforcements.
Seven full-scale specimens of the wall were made and tested under horizontal cyclic load in-plane, to investigate the potential effect of four variables (thickness of concrete layers, spacing of steel wires, concrete strength and axial compression ratio), and to evaluate the seismic performance of the new structure.
The remainder of this paper is organized as follows: Section 2 introduces the construction of this new-style structure, Section 3 describes the key points of the cyclic loading experiment, and Section 4 presents the failure patterns and mechanisms. In Section 5, the hysteretic curve, load-bearing capacity, ductility, stiffness degradation and energy dissipating capacity are analyzed based on the experimental results. The anti-seismic performance and influence of the main parameters are discussed in Section 6.
The structure system
Cast-in-situ insulated sandwich concrete walls
A cast-in-situ insulated sandwich concrete wall is composed of an expanded polystyrene sheet, steel wires, rectangular steel tubes, additional reinforcements and concrete layers, as shown in Fig 1.
A polystyrene sheet used as an insulation layer has a thickness of 80 mm and density of 20.4 kg/m3.
The steel wires are made of low carbon galvanized steel wires, including horizontal steel wires, vertical steel wires and slant steel wires, usually with a diameter of 2.5 mm. The horizontal steel wires and vertical steel wires are spot welded together at the intersection, with a steel wire spacing of 50 mm. The slant steel wires travel through the polystyrene sheet and the two ends are spot welded on the steel wire meshes composed of horizontal steel wires and vertical steel wires on both sides of the wall; the adjacent two columns of slant steel wires have opposite directions, and the angle between the slant steel wire and the polystyrene sheet is 72°, the spacing of slant steel wires is 50 mm, as shown in Fig 1. These operations are done mechanically, resulting in a polystyrene sheet welded to the steel wire meshes at the designed position.
Thin-walled cold-formed steel tubes are adopted with rectangular sections (70 mm×40 mm×1.5 mm), which are arranged in the openings of doors and windows, the center and edges of the wall, and welded on the steel tubes additional reinforcements that extend into the wall. Additional reinforcements are plain bars with a diameter of 6 mm and a spacing of 300 mm, as shown in Fig 1.
The thickness of concrete layers on both sides is identical (50 mm), as shown in Fig 1. Pea gravel concrete of C30 and below (according to GB/T 50081–2002 Chinese standard for test method of mechanical properties on ordinary concrete) is used, and the maximum particle size of coarse aggregate is limited to 10 mm. Concrete is constructed in situ.
Connecting joints of walls
The walls mainly bear vertical load and horizontal load. In order to ensure the complete transfer of horizontal load at the wall joint, the joint may bear bending, shearing and axial force. Therefore, different connection patterns are proposed for different joint forms. Four types of joint are used in this study: continuous joint of two walls (‘–’ shape), orthogonal joints of two walls (‘L’ shape), connecting joints of three walls (‘T’ shape) and orthogonal joints of four walls (‘+’ shape). Each type of joint targets at an overall performance regarding mechanical behavior of structure, thermal efficiency, feasibility of construction and economic feature.
The continuous joints of two walls (‘–’ shape) are constructed by setting formed steel and additional reinforcements at the joint, as shown in Fig 2(a).
The orthogonal joints of two walls (‘L’ shape) are constructed by setting reinforced concrete special-shaped columns and additional reinforcements at the junction of the two walls, as shown in Fig 2(b).
The connecting joints of three walls (‘T’ shape) and orthogonal joints of four walls (‘+’ shape) are constructed by setting reinforced concrete columns with additional reinforcements extended into each wall at the joint, as shown in Fig 2(c) and 2(d).
Experimental plan
The main purpose of the experiment is to observe the pseudo-static behavior of the single cast-in-situ insulated sandwich concrete walls under low-frequency horizontal cyclic load, to reveal how various parameters influence the mechanical properties and deformation of the wall, and to evaluate the seismic performance of the structure. With this aim, a full-scale test of quasi-static force is carried out.
Design of the experiment
Four parameters were varied: thickness of concrete layer t, steel wire spacing s, concrete strength fc and axial compression ratio λ. Accordingly, a total of seven specimens were made for experimental research. Parameters of each specimen is shown in Table 1.
Low frequency horizontal cyclic load and constant vertical load are applied to each specimen. The horizontal cyclic load is controlled by displacement, and the displacement of each level circulates twice until the horizontal load value drops to 85% of the peak load, so as to observe the pattern of strength degradation, stiffness degradation and damage development induced by repeated loading and unloading. The magnitude of vertical load is determined by the axial compression ratio. Two axial compression ratios are adopted, respectively representing different upper wall loads, to assess the influence of axial force.
Throughout the test, the relationship curve between load and displacement and failure mode are documented, which will be used to evaluate the mechanical properties of the wall and the influence of various research parameters.
Fabrication of specimens
All seven specimens measure 1900 mm in height and 1000 mm in width. All specimens have a total wall thickness of 230 mm (75+80+75) except for CWS-2 (210 = 65+85+65 mm) and CWS-3 (250 = 85+80+85 mm), as shown in Table 1. The specimens are divided into 3 parts vertically: loaded region (top 300 mm), supported region (bottom 100 mm), and tested region (1500 mm in between).
The specimens are fabricated in the following procedures.
Firstly, expanded polystyrene sheet (EPS) with steel wire arranged according to design is obtained through automatic processing machine: the spacing between horizontal steel wire and vertical steel wire is 50 mm, the horizontal and vertical spacing of the slant steel wire is also 50 mm, the angle between the slant steel wire and EPS plate is 72°. The thickness of expanded polystyrene is 80 mm, as shown in Fig 3(a). The EPS and steel wires are provided by Hebei Meizhu Energy Saving Technology Co. LTD.
Then, the reinforcements of the foundation beam and additional reinforcements are installed and tied. As shown in Fig 4 for detailed reinforcements of all specimens: at the junction between the wall and the foundation beam, additional reinforcements with a diameter of 6 mm are set at a spacing of 300 mm. The top 300 mm range of the specimen is the holding region of loading device, in order to prevent local concrete breakage caused by stress concentration. Additional steel bars with a diameter of 6 mm are also set at the junction of the holding region and the research region, with a spacing of 300 mm. Steel plates with a thickness of 14 mm are embedded at the side and top loading points of all specimens for the uniform transfer of horizontal and vertical loads, respectively, as shown in Fig 3(b).
Finally, concrete layers(provided by Shijiazhuang Shuntian Building Materials Co. LTD) on both sides of EPS insulation layer are cast with three different thicknesses of concrete layers: 65 mm, 75 mm and 85 mm. Typically, there are three cast-in-situ methods adopted in practice, such as manually plastered concrete, sprayed concrete and cast-in-place concrete with supporting formwork. The cast-in-situ concrete with supporting formwork is adopted in this experiment, as shown in Fig 3(c).
Material properties
The materials used in the specimens are typically used in construction sites. Three kinds of concrete (C20, C30 and C40, according to GB/T 50081–2002 Chinese standard for test method of mechanical properties on ordinary concrete) were tested for axial compression strength and splitting tensile strength, as shown in Fig 5(a) and 5(b). The steel wires in the specimen are made of low-carbon galvanized steel wire with a diameter of 2.5 mm, and the additional reinforcements are made of plain steel bars (HPB300, according to GB 50010–2010 Chinese code for design of concrete structures) with a diameter of 6 mm. Tensile tests were carried out respectively, as shown in Fig 5(c) and 5(d). The results of material property tests indicate that the galvanized steel wires used have no obvious yield stage, so the strength when the plastic elongation is 0.2% is taken as the conditional yield strength. The test results are shown in Table 2.
Test set-up
The test device consists of a reaction frame, a hydraulic actuator, and a sliding device. The holding device is installed on the top of the specimen. The horizontal cyclic load is applied by a double-acting hydraulic actuator through the holding device. The vertical load is applied by the vertical actuator through a load-bearing steel beam on the top of the specimen. The near end of the vertical actuator is a spherical hinge, and the root is fixed on the reaction frame by sliding device. The vertical actuator can slide freely along the loading direction of the horizontal actuator. The specimen foundation beam is fixed on the reaction frame with a high-strength bolt. In order to prevent rigid body slip-off of the specimen along the loading direction, a hydraulic jack is set at the southern end of the foundation beam along the horizontal loading direction to tighten the foundation, as shown in Fig 6. The above equipments are manufactured and supplied by Beijing Baoheyuan Photoelectric Equipment Co. LTD.
Four digital indicators each with a range of 50 mm and one draw-wire displacement sensor (both are manufactured by Beijing Jinghaiquan Sensor Technology Co. LTD) are applied to each specimen to measure its displacement, as shown in Fig 6:
Absolute horizontal displacement is measured by digital indicator No. 1 and No. 3 and the draw-wire displacement sensor.
The horizontal rigid body displacement of the foundation beam is measured by digital indicator No. 2 and No. 4.
During the loading process, the vertical load, horizontal load, and horizontal displacement are automatically collected by the DONGHUA-DH3821 data collection system, while the wall cracking and damage phenomena are observed by the naked eye.
Phenomena of tests
This section presents the cracking and final failure patterns of the single cast-in-place sandwich concrete panel specimens during loading.
At the initial stage of loading, all the specimens show horizontal bending cracks at the edges of wall, and they gradually develop as diagonal shear cracks with the displacement growth. Each specimen is damaged together with the diagonal shear cracks penetration in the lower part of the wall. Finally, the cracks develop to the bottom of the wall, forming a main crack with a considerable width and length in both directions. The two main cracks intersected in an “X” shape, determining the failure mode of the wall. Fig 7 illustrates the final form of failure of CWS-1.
Observations will be presented in groups according to different research parameters, wherein the panel CWS-1 is a reference specimen.
For the specimens with the thickness of the concrete layer as the variable: CWS-2 (t = 65 mm), CWS-1 (t = 75 mm), CWS-3 (t = 85 mm), the wire spacing is 50 mm, the reinforcement ratio is 0.13%, the axial compression ratio is 0.06, and the failure modalities of them are similar. Taking the CWS-1 as an example: the axial force applied to CWS-1 is 340 kN, and the ultimate displacement is 0.9% (15 mm). The first crack, nearly horizontal, is a bending crack generated at a height of approximately 630 mm (1/3 of specimen height) above the lower edge of the specimen at the negative cyclic displacement of -0.18% (-3 mm, F = -114 kN). When loaded to -0.24% (-4 mm, F = -132 kN), the crack extends diagonally as a shear crack. When loaded to -0.72% (-12 mm, F = -111 kN), the crack reaches the bottom of the specimen. When the load was increased to +0.5% (+8 mm, F = +143 kN) and +0.72% (+12 mm, F = +136 kN), a crack is created in the other direction, intersecting the existing crack. It is worth noting that CWS-1 and CWS-2 only produce one main crack in the positive and negative loading direction respectively, and the branch cracks are few; in contrast, the crack distribution of CWS-3 is denser, as shown in Fig 8(a), 8(b) and 8(c).
For CWS-4 with the wire spacing as the variable, the concrete layer thickness is 75 mm, the vertical axial force applied is 340 kN, the axial compression ratio is 0.06, the wire spacing is 100 mm, the reinforcement ratio is 0.07%, and the ultimate displacement is 1.0% (17 mm). When the negative cyclic displacement is -0.5% (-8 mm, F = -151 kN), a horizontal crack of 0.1 mm wide is produced at the bottom of the south side of the panel, which is a bending crack. A 0.1 mm wide horizontal crack is generated at the bottom of the north side of the panel when the positive cyclic displacement is +0.7% (+13 mm, F = +189 kN), and the two cracks are connected to each other. When the displacement gradually increases to -1.0% (-17 mm, F = -191 kN), the edge of the panel cracks suddenly with a loud burst and the cracks quickly penetrate to the bottom of the wall. The maximum width of the cracks is 4.5 mm. The cracks start horizontally, and then proceed diagonally. Finally, the specimens are damaged without omen. The reason for this may be the lower reinforcement ratio of CWS-4. In contrast, although the damage of CWS-1 also shows brittleness, it is not sudden, but rather gradual and manageable. See Fig 8 (a) and 8(d).
For the specimens CWS-5 and CWS-6 with concrete strength as the variable, the concrete layer thickness is 75 mm, the wire spacing is 50 mm, the reinforcement ratio is 0.13%, the vertical axial force applied are 220 kN and 400 kN respectively, the axial compression ratio is 0.06, the ultimate displacements are 1.7% (28 mm) and 1.0% (18 mm), the concrete strength grades of specimens CWS-5 and CWS-6 are C20 and C40 respectively, and the cracking patterns of them are similar. The CWS-5 specimen is taken as an example for description. For CWS-5, a horizontal crack is generated in the center and lower part of the north side of the panel at a positive cyclic displacement of +0.24% (+4 mm, F = +123 kN), which is a bending crack. When the positive cyclic displacement is +0.36% (+6 mm, F = +136 kN), the crack develops diagonally as a shear crack. On the other hand, when the negative cyclic displacement is -0.36% (-6 mm, F = -112 kN), a shear crack is also generated along the diagonal direction, and the two cracks intersect with each other and stretch to the bottom of the specimen. Compared with CWS-1, the failure patterns of the three are similar, but the cracks in CWS-5 are slightly denser, indicating that the strength of concrete has little effect on the failure pattern of single cast-in-situ insulated concrete wall, as shown in Fig 8(a), 8(e) and 8(f).
For the specimen CWS-7 with the axial compression ratio as the variable, the concrete layer thickness is 75 mm, the wire spacing is 50 mm, the reinforcement ratio is 0.13%, the vertical axial force applied is 600 kN, the axial compression ratio is 0.12, and the ultimate displacement is 1.9% (32 mm). The first crack is observed in the center of the north side of the specimen when the positive cyclic displacement is +0.45% (+8 mm, F = +196 kN). When the negative cyclic displacement is -0.45% (-8 mm, F = -156 kN), another crack is formed in the lower middle part of the south side of the specimen. Both cracks are horizontal. When the displacement reaches 0.8% (14 mm, F = +232 kN), the cracks develop diagonally, and as the displacement gradually increases, cracks continue to occur until the specimen is destroyed. Compared with CWS-1, the crack position of CWS-7 is higher. Although the number of cracks is comparable between the two specimens, CWS-7 has a larger width of cracks, a number of branch cracks, a denser distribution of cracks, more serious damages and spalling. This is seen in Fig 8(a) and 8(g).
Experimental results and structural parameter study
Hysteresis curves and skeleton curves
The hysteresis curves and skeleton curves of seven specimens are shown and compared in Figs 9 and 10 respectively. All specimens have similar hysteresis behavior. The specimens exhibit linear elastic behavior with low energy dissipation before cracking. As the horizontal displacement gradually increases, hysteresis occurs with high energy dissipation in all specimens.
The hysteresis curves of all specimens are in the same pattern in both positive and negative loading directions. The envelopes of hysteresis curves in the positive and negative directions are asymmetrical, as shown in Fig 9 (the red and blue curves represent the envelope of positive and negative loading, respectively). Except for CWS-2, the envelope in the negative direction is lower than the envelope in the positive direction because the main diagonal crack in the positive direction develops earlier than the crack in the negative direction. The main diagonal crack of CWS-2 occurs in the negative loading direction first, so the envelope in the negative direction is higher. This may be due to fabrication defects.
The parameter study of the hysteresis curves is as follows:
The thicknesses of concrete layers t of CWS-1, CWS-2 and CWS-3 are 75 mm, 65 mm and 85 mm, respectively. For CWS-1 and CWS-2, there is no obvious yielding. The hysteresis curves are narrow and pinch phenomenon is obvious. Also, the peak load is reached at the drift ratio of 0.5%, as shown in Fig 9(a) and 9(b). For CWS-3, the hysteresis curve is plump and there is no obvious pinch phenomenon. The peak load of CWS-3 is reached at the drift ratio of 1.2% (See Fig 9(c)). Fig 10(a) shows a comparison of skeleton curves of these three specimens. It is seen that with the increase of the thickness of concrete layer the peak load increases and the residual deformation at unloading increases significantly.
The spacing s between wires (either horizontal or vertical) in specimens CWS-1 and CWS-4 are 50 mm and 100 mm. There is no descending branch in the hysteresis curve of CWS-4. There is almost no residual deformation and the specimen CWS-4 breaks suddenly. This tells CWS-4 experiences brittle failure. The reinforcement ratio of CWS-4 is low (0.07%). For CWS-4 the steel wire is broken at the same time of the concrete crushing, while for CSW-1 the strength degradation occurs and structural behavior is more ductile, as shown in Fig 9(a) and 9(d).
The concrete grades of specimens CWS-1, CWS-5 and CWS-6 are C30, C20 and C40. The hysteresis curves of these three are very similar. There is no obvious yielding and the peak loads are close to each other (peak loads are 138, 147 and 139 kN respectively). The hysteresis curve of CWS-5 is slightly plumper because CWS-5 has a better deformation capacity. The ultimate displacement of CWS-5 is 1.6% comparing with 0.9% of CWS-1 and 1.0% of CWS-6 (See Fig 9(a), 9(e) and 9(f)). In addition, Fig 10(c) shows the skeleton curves of these three specimens are very close to each other. It can be concluded that the horizontal bearing capacity of wall is not significantly affected by concrete strength and that the deformation capacity increases as the concrete strength decreases.
The axial compression ratios of specimens CWS-1 and CSW-7 are 0.06 and 0.12, respectively, corresponding to axial forces of 340 kN and 600 kN. The other parameters for these two specimens are the same. It is seen in Figs 9(g) and 10(d) that with a bigger ratio of axial compression stress to strength, the bearing capacity is significantly increased and the descending branch of the envelope of the hysteresis curve becomes much steeper. The steeper descending branch means faster strength degradation after the peak load. Note that the residual deformation of CWS-7 in the negative loading direction is significantly larger than that in the positive direction. This is because CWS-7 only develops one main diagonal crack in the positive direction which extends to the bottom of the wall and penetrates through the whole thickness of the wall at a drift ratio of 0.5% (8 mm, F = +196 kN). This major crack causes severe pinching effect in the hysteresis curve of CWS-7 in positive direction, while more cracks are generated in the negative direction as the increase of displacement, as shown in Fig 8(g).
Bearing capacity and ductility
The most common methods to determine the yielding point are the energy equivalent method, the geometric mapping method and the R. Park method [25]. The R. Park method is used here. Fig 11 shows the principle of the R. Park method. In general, 85% of the peak load Fp is taken as the ultimate load, and the corresponding displacement is defined as the ultimate displacement. However, for some specimens (e.g. CSW-5), the failure occurs before the load drops to 85% of the peak load. In this case, the last stage of the cyclic load is taken as the limit state. The load and displacement at the limit state are taken as the ultimate load and ultimate displacement for these specimens.
The displacement ductility factor μ is defined as the ratio of the ultimate displacement Δu to the yield displacement Δy [26]. The yield load Fy, peak load Fp, ultimate load Fu, the corresponding displacements and displacement ductility factor μ of all specimens are listed in Table 3.
From Table 3, several conclusions are drawn as follows.
The concrete layer thickness t has an evident correlation with the horizontal bearing capacity. The horizontal peak load increases by 25% (from 132 to 165 kN) when the concrete layer thickness is increased by 30% (from 65 to 85 mm). In addition, the displacement ductility factor ratios of CWS-1, CWS-2 and CWS-3 (1.0, 1.54 and 0.84) indicate that the specimen has a better deformation ability and ductility with less concrete layer thickness.
Steel wire spacing s has little influence on the bearing capacity, but significant influence on the ductility of the specimens. The displacement ductility factor μ significantly decreases (from 1.0 to 0.75) when the steel wire spacing is increased (from 50 mm to 100 mm). The smaller the wire spacing is, the greater the ductility is.
The concrete strength fc has little effect on the lateral bearing capacity. This is due to a low reinforcement ratio which can’t make the full use of concrete strength. The crack develops in the specimens at a low load level, and the lateral bearing capacity is controlled by concrete tensile strength, which fails to give full play to the good compressive strength of concrete. Based on the displacement ductility factor ratios of CWS-1, CWS-5 and CWS-6 (1.0, 1.34 and 1.16), the lower the concrete strength, the better the ductility.
The axial compression ratio has a significant effect on the lateral bearing capacity. Greater axial compression ratio gives higher bearing capacity. As the axial compression ratio increases from 0.06 to 0.12, the bearing capacity is increased by 58% (from 138 to 219 kN). Meanwhile, the ductility decreases from 1.0 to 0.88.
Stiffness
The stiffness of a specimen is expressed by secant stiffness Ki, which is defined by Eq 1 as in [26]:
Fig 12 shows the secant stiffness versus lateral horizontal displacement of all specimens. It can be observed that the secant stiffness of all specimens decreases rapidly at the initial loading stage, and then tends to be flat until the end of the test.
Under in-plane lateral cyclic load, the stiffness degradation of the wall depends on the degree of damage during the cyclic response. Fig 13 shows the stiffness degradation of all specimens according to the grouping of research parameters, adopting the stiffness degradation ratio (i.e., the ratio of secant stiffness Ki of the i-th cycle to the secant stiffness K1 of the first cycle).
For CWS-1(t = 75 mm), CWS-2(t = 65 mm) and CWS-3 (t = 85 mm) (Fig 13(a)), CWS-2 exhibits faster stiffness degradation because the concrete layer of CWS-2 is thinner and the cracks run through the entire concrete layer after the concrete cracks, leading to greater damage to the specimen. In the initial stage of loading, the stiffness degradation rate of CWS-1 and CWS-3 is similar, the concrete layer of CWS-1 cracks when the displacement reaches 4 mm, and the stiffness of CWS-1 decreases rapidly until it is failure. In contrast, the degradation of stiffness of CWS-3 occurred gradually; the reason for this is that the concrete layers of the CWS-3 are thicker and the cracks are developed gradually.
For CWS-1(s = 50 mm) and CWS-4 (s = 100 mm) (Fig 13(b)), at the initial stage of loading(the displacement is less than 6 mm), the stiffness degradation rate is similar, but after that, the stiffness degradation rate of CWS-1 is faster; this may be because in the later stage of loading, no obvious damages appeared to CWS-4 until the displacement reached 17 mm, when it is suddenly destroyed.
For CWS-1 (fcp = 34.36 MPa), CWS-5(fcp = 24.39 MPa) and CWS-6 (fcp = 44.69 MPa) (Fig 13(c)), at the early stage of loading (where the displacement is less than 10 mm), the stiffness degradation curves are almost identical; at the later stage of loading, the stiffness degradation rate of CWS-5 is relatively gentle because the fracture distribution is relatively dense, and the damage of CWS-5 is gradually generated.
For CWS-1 (λ = 0.06) and CWS-7 (λ = 0.12) (Fig 13(d)), at the initial stage of loading (where the displacement is less than 4 mm), the stiffness degradation rates are similar; the main diagonal crack of the CWS-1 has been developed to the bottom of the wall after that, causing large damage and rapid stiffness degradation. However, the main diagonal cracks of CWS-7 are not completely connected but gradually develop with the increase of displacement, due to the large vertical axial force. Compared with CWS-1, the damage of CWS-7 is relatively small, so the degradation rate of stiffness is relatively gentle.
Energy dissipation capacity
Energy dissipation ratio E is often used to measure the energy dissipation capacity of the structure. It is defined by Eq (2), as in [26]:
The larger the energy dissipation ratio is, the plumper the hysteresis curve is and the stronger the energy dissipation capacity of the structure is. Fig 15 shows the energy dissipation ratio versus the loading displacement of each specimen by grouping the research parameters. It can be seen from Fig 15 that, in the initial stage of loading (before the displacement is about 5 mm), the energy dissipation ratio of all specimens decreases rapidly; after that, a continuous trough appeared, and the length and value are different with the different structures or loading devices; finally, the energy dissipation ratio of all specimens shows an upward trend. The reasons for this phenomenon are:
In the initial stage of loading, the deformation of the specimen is in the elastic stage, and the hysteresis curve can hardly show hysteresis. The hysteresis loop is narrow and long, and the energy dissipation property is low, so the energy dissipation ratio decreases rapidly.
Since the first crack has appeared, the specimen begins to dissipate energy through the opening and closing of concrete cracks. With the continuous increase of lateral horizontal displacement, the depth and size of existing cracks gradually become larger and new cracks are generated. The bond slip between steel wire and concrete also gradually contributes to energy dissipation. Therefore, the energy dissipation ratio E in Fig 15 experiences a fluctuation range and then begins to rise.
At the later stage of loading, the main diagonal cracks have formed and gradually spread through the entire section. After the peak point, the hysteresis of the hysteresis curve increases significantly. At this time, the deformation and fracture of the steel wire and friction between cracks of concrete become the main contributors to energy dissipation. Although the energy dissipation ratio starts to increase, due to the low reinforcement ratio and the initial cracks of the specimens, the bearing capacity begins to decline with the increase of displacement, and the test is finished as the specimen approaches the ultimate state.
From the comparative analysis in Fig 15, the following observations are made:
The thicker the concrete layer, the better the energy dissipation performance. As shown in Fig 15(a), the energy dissipation ratio of CWS-2 decreases the fastest at the initial stage of loading, because the crack penetrates through the wall earlier.
The steel wire spacing has a great influence on the energy dissipation of the structure. Because the horizontal and vertical steel wire spacing are equal, the size of the steel wire spacing represents the horizontal and vertical reinforcement ratio of the wall. It can be seen from Fig 15(b) that when the steel wire spacing is low (that is, when the reinforcement ratio is high), the energy dissipation performance is better.
As seen from Fig 15(c), when the strength of concrete is small, the specimen has a better energy dissipation performance. This is because the higher the strength of concrete is, the worse its ductility is.
According to Fig 15(d), when the axial compression ratio λ is relatively small, the energy dissipation performance is better, which may be due to the fact that when λ is relatively large, the specimens are destroyed more violently, and the ductility is poor.
Conclusions
Pseudo-static tests were carried out on seven full-scale single insulated sandwich concrete cast-in-situ wall specimens. Four different parameters, such as concrete layer thickness, steel wire spacing, concrete strength and axial compression ratio, were considered. The main results obtained from the seven tests can be summarized as follows:
Under in-plane horizontal cyclic load, all specimens show similar failure modes: in both positive and negative loading directions, a main diagonal crack is found respectively at a height of approximately 630 mm (1/3 of specimen height) above the lower edge of the specimen, and the two main cracks intersected in an ‘X’ shape. These two cracks predominated and defined the final failure pattern of the wall.
When all the specimens failed, the concrete layers on either side are not detached from the polystyrene layer in between, which indicates that the slant steel wire shear connector can guarantee the overall working performance of the insulated sandwich concrete cast-in-situ wall.
The hysteretic curve of the specimens with larger concrete layer thickness is plumper, showing better energy dissipation capacities. The hysteretic curves of specimen with large steel wire spacing show serious pinching phenomenon, small plastic deformation, sudden destruction and poor energy dissipation performance.
The horizontal bearing capacity is significantly affected by concrete layer thickness and axial compression ratio, but less affected by concrete strength. In addition, a better ductility can be achieved by lowering concrete strength, thickness concrete layer or axial compression ratio.
When secant stiffness is used as an indicator of stiffness degradation, it is found that the rate of stiffness degradation is gentler when the concrete layer is thicker. It is also found that the strength of concrete has little effect on the rate of stiffness degradation.
Energy dissipation ratio is used to represent energy dissipation performance. The results show that the concrete layer is thicker, the energy dissipation performance is better when the steel wire spacing is smaller, the concrete strength is lower, and the axial compression is smaller.
Suggestions
According to the research results of this paper, the following suggestions are given to make the insulated sandwich concrete panel structure used more efficiently in actual construction.
For the concrete layer thickness, 50~60mm is a reasonable range.
Improving the reinforcement ratio and adding the lateral constraint members such as RC or profile steel columns can effectively improve the seismic performance.
Prefabricated ISCP is a good way to simplify and accelerate the construction of this structure.
To improve the non-continuity of insulation layer in traditional structure, the new joint construction is proposed in this paper, which are shown in Fig 2.
To improving the insulation of steel shear connectors, the hybrid connectors, i.e., covering the surface of steel elements by using the insulating material, have been proposed.
In non-load-bearing components, it is a good way to improve the thermal efficiency by using foamed concrete layer as two side plates.
Supporting information
S1 Data [rar]
Experiment data for all specimens.
Zdroje
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- Live observation of the oviposition process in Daphnia magna
- On the accuracy of displacement-based wave intensity analysis: Effect of vessel wall viscoelasticity and nonlinearity
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- Differences in clinical features of cluster headache between drinkers and nondrinkers in Japan
- Distribution of macular ganglion cell layer thickness in foveal hypoplasia: A new diagnostic criterion for ocular albinism
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- The prognostic significance of tumor-infiltrating lymphocytes assessment with hematoxylin and eosin sections in resected primary lung adenocarcinoma
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- Modulating transcription through development of semi-synthetic yeast core promoters
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- Validation of the group tasks uncertainty model (MITAG) in a German sample
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- Insight into the relationship between aryl-hydrocarbon receptor and β-catenin in human colon cancer cells
- Hidden noise in immunologic parameters might explain rapid progression in early-onset periodontitis
- The role of stigma in the acceptance and disclosure of HIV among recently diagnosed men who have sex with men in Australia: A qualitative study
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- Questioning the lasting effect of galvanic vestibular stimulation on postural control
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- Nonalcoholic fatty liver disease is an early predictor of metabolic diseases in a metabolically healthy population
- Occurrence and multilocus genotyping of Giardia duodenalis from post-weaned dairy calves in Sichuan province, China
- Retinoic acid-stimulated ERK1/2 pathway regulates meiotic initiation in cultured fetal germ cells
- Gender disparities in scientific production: A nationwide assessment among physicians in Peru
- Effect of F1 and F2 generations on genetic variability and working steps of doubled haploid production in maize
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- A handy method to remove bacterial contamination from fungal cultures
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- The mutational landscape of quinolone resistance in Escherichia coli
- Exploring the influence of self-perceptions on the relationship between motor competence and identity in adolescents
- Study on the damage characteristics of gas-bearing shale under different unloading stress paths
- EPILAT-IRA Study: A contribution to the understanding of the epidemiology of acute kidney injury in Latin America
- 16S rDNA droplet digital PCR for monitoring bacterial DNAemia in bloodstream infections
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- Diversity of endocervical microbiota associated with genital Chlamydia trachomatis infection and infertility among women visiting obstetrics and gynecology clinics in Malaysia
- Health impact of hepatic-venous-occlusive disease in a small town in Ethiopia—Case study from Tahtay koraro district in Tigray region, 2017
- Development of a novel automatable fabrication method based on electrospinning co electrospraying for rotator cuff augmentation patches
- Development of a quantitative PCR assay for the detection and enumeration of a potentially ciguatoxin-producing dinoflagellate, Gambierdiscus lapillus (Gonyaulacales, Dinophyceae)
- Association of clinical factors with survival outcomes in laryngeal squamous cell carcinoma (LSCC)
- Seasonal oyster harvesting recorded in a Late Archaic period shell ring
- Population preferences for breast cancer screening policies: Discrete choice experiment in Belarus
- Respiratory health and inflammatory markers - Exposure to respirable dust and quartz and chemical binders in Swedish iron foundries
- Trends and predictors of mother-to-child transmission of HIV in an era of protocol changes: Findings from two large health facilities in North East Nigeria
- Elevated Ki-67 (MIB-1) expression as an independent predictor for unfavorable pathologic outcomes and biochemical recurrence after radical prostatectomy in patients with localized prostate cancer: A propensity score matched study
- Genome-wide identification and gene expression analysis of SOS family genes in tuber mustard (Brassica juncea var. tumida)
- Carvedilol improves glucose tolerance and insulin sensitivity in treatment of adrenergic overdrive in high fat diet-induced obesity in mice
- Institutional differences in USMLE Step 1 and 2 CK performance: Cross-sectional study of 89 US allopathic medical schools
- Molecular epidemiological characteristics of dengue virus carried by 34 patients in Guangzhou in 2018
- Heteroplasmy in the complete chicken mitochondrial genome
- Candida blood stream infections observed between 2011 and 2016 in a large Italian University Hospital: A time-based retrospective analysis on epidemiology, biofilm production, antifungal agents consumption and drug-susceptibility
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- Association of uric acid in serum and urine with subclinical renal damage: Hanzhong Adolescent Hypertension Study
- Appropriate management of acute gastroenteritis in Australian children: A population-based study
- The plasma metabolome of women in early pregnancy differs from that of non-pregnant women
- Effectiveness of four types of neuraminidase inhibitors approved in Japan for the treatment of influenza
- More than just availability: Who has access and who administers take-home naloxone in Baltimore, MD
- Evaluating the cross-cultural validity of the Dutch version of the Social Exclusion Index for Health Surveys (SEI-HS): A mixed methods study
- Diminuendo al bottom—Clarifying the semantics of music notation by re-modeling
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- Serum uromodulin is associated with the severity of clinicopathological findings in ANCA-associated glomerulonephritis
- Male support for cervical cancer screening and treatment in rural Ghana
- ADAPTS: Automated deconvolution augmentation of profiles for tissue specific cells
- Comparison of shape quantification methods for genomic prediction, and genome-wide association study of sorghum seed morphology
- An attempt to identify the issues underlying the lack of consistent conceptualisations in the field of student mathematics-related beliefs
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- Effects of light and nitrogen availability on photosynthetic efficiency and fatty acid content of three original benthic diatom strains
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- Bioinformatic analysis of a novel Echinococcus granulosus nuclear receptor with two DNA binding domains
- Genome-wide identification and characterization, phylogenetic comparison and expression profiles of SPL transcription factor family in B. juncea (Cruciferae)
- Hypoxia inhibits TNF-α-induced TSLP expression in keratinocytes
- Conceptualising alcohol consumption in relation to long-term health conditions: Exploring risk in interviewee accounts of drinking and taking medications
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- Involvement of extracellular vesicles in the macrophage-tumor cell communication in head and neck squamous cell carcinoma
- Comparison of Humphrey Field Analyzer and imo visual field test results in patients with glaucoma and pseudo-fixation loss
- Out-of-pocket expenditure and catastrophic health expenditure for hospitalization due to injuries in public sector hospitals in North India
- Concurrent validity and discriminative ability of Dutch performance-based motor tests in 5 to 6 years old children
- Cumulative viral load as a predictor of CD4+ T-cell response to antiretroviral therapy using Bayesian statistical models
- Can General Practitioners manage mental disorders in primary care? A partially randomised, pragmatic, cluster trial
- Self-serving incentives impair collective decisions by increasing conformity
- Mutation and immune profiling of metaplastic breast cancer: Correlation with survival
- The clinicopathological significance of Thrombospondin-4 expression in the tumor microenvironment of gastric cancer
- Propofol-based total intravenous anesthesia did not improve survival compared to desflurane anesthesia in breast cancer surgery
- Association between ossification of the posterior longitudinal ligament and ossification of the nuchal ligament in the cervical spine
- Effects of Debaryomyces hansenii treatment on intestinal mucosa microecology in mice with antibiotic-associated diarrhea
- Molecular validation of clinical Pantoea isolates identified by MALDI-TOF
- A novel wheat lodging resistance evaluation method and device based on the thrust force of the stalks
- Evolution of high tooth replacement rates in theropod dinosaurs
- Outpatient facility-based order variation in combined imaging
- Ethnic-racial identity affirmation: Validation in Aboriginal Australian children
- Non-intubated anesthesia in patients undergoing video-assisted thoracoscopic surgery: A systematic review and meta-analysis
- Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages
- Changes of serum pentraxin-3 and hypersensitive CRP levels during pregnancy and their relationship with gestational diabetes mellitus
- Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake
- Investigating reindeer pastoralism and exploitation of high mountain zones in northern Mongolia through ice patch archaeology
- Diversity pattern of Plasmodium knowlesi merozoite surface protein 4 (MSP4) in natural population of Malaysia
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- “What gets measured better gets done better”: The landscape of validation of global maternal and newborn health indicators through key informant interviews
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- The impact of “male clinics” on health-seeking behaviors of adult men in rural Kenya
- Gene expression microarray public dataset reanalysis in chronic obstructive pulmonary disease
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- Comparative efficacy of tenofovir and entecavir in nucleos(t)ide analogue-naive chronic hepatitis B: A systematic review and meta-analysis
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- Mathematical modeling reveals the factors involved in the phenomena of cancer stem cells stabilization
- Effects of forest management and roe deer impact on a mountain forest development in the Italian Apennines: A modelling approach using LANDIS-II
- Evaluation of comprehensive improvement for mild and moderate soil salinization in arid zone
- Efficacy, acceptability and feasibility of daily text-messaging in promoting glycaemic control and other clinical outcomes in a low-resource setting of South Africa: A randomised controlled trial
- Magnitude and associated factors of postpartum depression among women in Nekemte town, East Wollega zone, west Ethiopia, 2019: A community-based study
- Comparison of continuous wave and cold lateral condensation filling techniques in 3D printed simulated C-shape canals instrumented with Reciproc Blue or Hyflex EDM
- Effect of caffeine on neuromuscular function following eccentric-based exercise
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- The gut microbiome of freshwater Unionidae mussels is determined by host species and is selectively retained from filtered seston
- Alcohol consumption and survival after breast cancer diagnosis in Japanese women: A prospective patient cohort study
- Selection of reference genes for normalization of cranberry (Vaccinium macrocarpon Ait.) gene expression under different experimental conditions
- The household economic costs associated with depression symptoms: A cross-sectional household study conducted in the North West province of South Africa
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- Acute low- compared to high-load resistance training to failure results in greater energy expenditure during exercise in healthy young men
- Impact of body mass index and metabolically unhealthy status on mortality in the Japanese general population: The JMS cohort study
- Characterization of two thermophilic cellulases from Talaromyces leycettanus JCM12802 and their synergistic action on cellulose hydrolysis
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- Highly accurate prediction of flammability limits of chemical compounds using novel integrated hybrid models
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- The effect of climate change on cholera disease: The road ahead using artificial neural network
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- Improving the antimicrobial efficacy against resistant Staphylococcus aureus by a combined use of conjugated oligoelectrolytes
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- Association between housing tenure and self-rated health in Japan: Findings from a nationwide cross-sectional survey
- Investigation of biochemical and physiological parameters of the newborn Saiga antelope (Saiga tatarica) in Gansu Province, China
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- Perception of potential harm and benefits of HIV vaccine trial participation: A qualitative study from urban Tanzania
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- Acute Influenza A virus outbreak in an enzootic infected sow herd: Impact on viral dynamics, genetic and antigenic variability and effect of maternally derived antibodies and vaccination
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- Genetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches
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- Comparative distribution of extended-spectrum beta-lactamase–producing Escherichia coli from urine infections and environmental waters
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- The association between self-efficacy and self-management behaviors among Chinese patients with type 2 diabetes
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- Affective disorders in the elderly in different European countries: Results from the MentDis_ICF65+ study
- Evaluation of forearm vascular resistance during orthostatic stress: Velocity is proportional to flow and size doesn’t matter
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- Maternal stress in Shank3ex4-9 mice increases pup-directed care and alters brain white matter in male offspring
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- Exploiting open source 3D printer architecture for laboratory robotics to automate high-throughput time-lapse imaging for analytical microbiology
- Long non-coding RNAs and latent HIV – A search for novel targets for latency reversal
- Clinical characteristics of neonatal fulminant necrotizing enterocolitis in a tertiary Children's hospital in the last 10 years
- Effects of neuromuscular electrical stimulation training on muscle size in collegiate track and field athletes
- Adaptive fuzzy flow rate control considering multifractal traffic modeling and 5G communications
- Evaluation of four commercial tests for detecting ceftiofur in waste milk bulk tank samples
- A smart tele-cytology point-of-care platform for oral cancer screening
- Vasopressin SNP pain factors and stress in sickle cell disease
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- Microbial metabolisms in an abyssal ferromanganese crust from the Takuyo-Daigo Seamount as revealed by metagenomics
- Incidence of chronic kidney disease hospitalisations and mortality in Espírito Santo between 1996 to 2017
- The impact of short-term machine perfusion on the risk of cancer recurrence after rat liver transplantation with donors after circulatory death
- Proteomic profiling of the thrombin-activated canine platelet secretome (CAPS)
- Blood metal levels and serum testosterone concentrations in male and female children and adolescents: NHANES 2011–2012
- The effects of prolonged single night session of videogaming on sleep and declarative memory
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- Mapping developmental QTL for plant height in soybean [Glycine max (L.) Merr.] using a four-way recombinant inbred line population
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- UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal
- Positive selection and precipitation effects on the mitochondrial NADH dehydrogenase subunit 6 gene in brown hares (Lepus europaeus) under a phylogeographic perspective
- Evaluation of Minimum Inhibitory Concentrations for 154 Mycoplasma synoviae isolates from Italy collected during 2012-2017
- Enhancement of antibiotics antimicrobial activity due to the silver nanoparticles impact on the cell membrane
- Correction: Smoking, alcohol use disorder and tuberculosis treatment outcomes: A dual co-morbidity burden that cannot be ignored
- Correction: Effect of corruption on perceived difficulties in healthcare access in sub-Saharan Africa
- Knowledge-based best of breed approach for automated detection of clinical events based on German free text digital hospital discharge letters
- Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects
- Integrated value-chain and risk assessment of Pig-Related Zoonoses in Ghana
- Failed sperm retrieval from severely oligospermic or non-obstructive azoospermic patients on oocyte retrieval day: Emergent oocyte cryopreservation is a feasible strategy
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- Verification of hub genes in the expression profile of aortic dissection
- Pig farmers’ willingness to pay for management strategies to reduce aggression between pigs
- Metabolomic response of Euglena gracilis and its bleached mutant strain to light
- Diagnostic value of ASVS for insulinoma localization: A systematic review and meta-analysis
- Newly educated care managers’ experiences of providing care for persons with stress-related mental disorders in the clinical primary care context
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- Qualification programmes for immigrant health professionals: A systematic review
- An analytical model to minimize the latency in healthcare internet-of-things in fog computing environment
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- Evaluation of cytological diagnostic accuracy for canine splenic neoplasms: An investigation in 78 cases using STARD guidelines
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- Assessment of energy expenditure during high intensity cycling and running using a heart rate and activity monitor in young active adults
- Evaluating rectal swab collection method for gut microbiome analysis in the common marmoset (Callithrix jacchus)
- Implementation of a screening, brief intervention and referral to treatment programme for risky substance use in South African emergency centres: A mixed methods evaluation study
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- The calcium sensor OsCBL1 modulates nitrate signaling to regulate seedling growth in rice
- Acceptability of and treatment preferences for recurrent bacterial vaginosis—Topical lactic acid gel or oral metronidazole antibiotic: Qualitative findings from the VITA trial
- Mathematical determination of the HIV-1 matrix shell structure and its impact on the biology of HIV-1
- Contingent negative variation during a modified cueing task in simulated driving
- CAMDI interacts with the human memory-associated protein KIBRA and regulates AMPAR cell surface expression and cognition
- Effect of feeding patterns on growth and nutritional status of children aged 0-24 months: A Chinese cohort study
- A fecal sequel: Testing the limits of a genetic assay for bat species identification
- Measuring the impact of chronic conditions and associated multimorbidity on health-related quality of life in the general population in Hong Kong SAR, China: A cross-sectional study
- Short and long-term clinical effectiveness and cost-effectiveness of a late-phase community-based balance and gait exercise program following hip fracture. The EVA-Hip Randomised Controlled Trial
- Vaccine cold chain in general practices: A prospective study in 75 refrigerators (Keep Cool study)
- Brazilian norms for the Bank of Standardized Stimuli (BOSS)
- Distinct varieties of aesthetic chills in response to multimedia
- Interaction between apolipoprotein E genotype and hypertension on cognitive function in older women in the Nurses’ Health Study
- Correction: Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study
- New formulation of the Gompertz equation to describe the kinetics of untreated tumors
- Development of visual perception of others’ actions: Children’s judgment of lifted weight
- Retrospective comparative analysis of intraocular lens calculation formulas after hyperopic refractive surgery
- Human vitreous concentrations of citicoline following topical application of citicoline 2% ophthalmic solution
- Development and validation of exhaled breath condensate microRNAs to identify and endotype asthma in children
- Arthroscopic release for frozen shoulder: Does the timing of intervention and diabetes affect outcome?
- Risk factors affecting dairy cattle protective grouping behavior, commonly known as bunching, against Stomoxys calcitrans (L.) on California dairies
- Acceleration of chemical shift encoding-based water fat MRI for liver proton density fat fraction and T2* mapping using compressed sensing
- Characterisation and microbial community analysis of lipid utilising microorganisms for biogas formation
- Sexuality in male partners of women with fibromyalgia syndrome: A qualitative study
- Exploring optimization strategies for improving explicit water models: Rigid n-point model and polarizable model based on Drude oscillator
- Artificial insemination with fresh, liquid stored and frozen thawed semen in dromedary camels
- Moving into an urban drug scene among people who use drugs in Vancouver, Canada: Latent class growth analysis
- Numerical study on the start and unstart phenomena in a scramjet inlet-isolator model
- Effects of dietary supplementation with apple peel powder on the growth, blood and liver parameters, and transcriptome of genetically improved farmed tilapia (GIFT, Oreochromis niloticus)
- Urban growth simulation in different scenarios using the SLEUTH model: A case study of Hefei, East China
- Chronic bronchitis without airflow obstruction, asthma and rhinitis are differently associated with cardiovascular risk factors and diseases
- Factors associated with medication adherence among people with diabetes mellitus in poor urban areas of Cambodia: A cross-sectional study
- Mammary microbiome of lactating organic dairy cows varies by time, tissue site, and infection status
- Force field generalization and the internal representation of motor learning
- Polyphenism of visual and chemical secondary sexually-selected wing traits in the butterfly Bicyclus anynana: How different is the intermediate phenotype?
- Minimal genetic differentiation of the malaria vector Nyssorhynchus darlingi associated with forest cover level in Amazonian Brazil
- The impact of leisure activities on older adults’ cognitive function, physical function, and mental health
- scafSLICR: A MATLAB-based slicing algorithm to enable 3D-printing of tissue engineering scaffolds with heterogeneous porous microarchitecture
- Association of serum leptin and adiponectin concentrations with echocardiographic parameters and pathophysiological states in patients with cardiovascular disease receiving cardiovascular surgery
- Operation of cognitive memory inhibition in adults with Down syndrome: Effects of maintenance load and material
- Influences on surgical antimicrobial prophylaxis decision making by surgical craft groups, anaesthetists, pharmacists and nurses in public and private hospitals
- Post-treatment Lyme disease symptoms score: Developing a new tool for research
- Expression of Concern: The Role of the RACK1 Ortholog Cpc2p in Modulating Pheromone-Induced Cell Cycle Arrest in Fission Yeast
- Equine bronchial fibroblasts enhance proliferation and differentiation of primary equine bronchial epithelial cells co-cultured under air-liquid interface
- Investigating cooperation with robotic peers
- Synthesis, purification and crystallization of a putative critical bulge of HAR1 RNA
- Prosthetic push-off power in trans-tibial amputee level ground walking: A systematic review
- A case study of the use of verbal reports for talent identification purposes in soccer: A Messi affair!
- Transgenerational deep sequencing revealed hypermethylation of hippocampal mGluR1 gene with altered mRNA expression of mGluR5 and mGluR3 associated with behavioral changes in Sprague Dawley rats with history of prolonged febrile seizure
- Obesity is associated with an impaired survival in lymphoma patients undergoing autologous stem cell transplantation
- Periodontal disease: Repercussions in pregnant woman and newborn health—A cohort study
- Origins of Chinese reindeer (Rangifer tarandus) based on mitochondrial DNA analyses
- Regional, racial, gender, and tumor biology disparities in breast cancer survival rates in Africa: A systematic review and meta-analysis
- How effective are films in inducing positive and negative emotional states? A meta-analysis
- 3D nanostructural characterisation of grain boundaries in atom probe data utilising machine learning methods
- An outbreak of tuberculosis in a middle school in Henan, China: Epidemiology and risk factors
- Initial clinical radiological findings and staging to predict prognosis of primary hepatic angiosarcoma: A retrospective analysis
- A new early Eocene deperetellid tapiroid illuminates the origin of Deperetellidae and the pattern of premolar molarization in Perissodactyla
- Longevity and marginal bone loss of narrow-diameter implants supporting single crowns: A systematic review
- Impact of UVC-sustained recirculating air filtration on airborne bacteria and dust in a pig facility
- Cold-related Florida manatee mortality in relation to air and water temperatures
- Conceptual fluency in inductive reasoning
- Clinical outcomes and treatment patterns among Medicare patients with nonvalvular atrial fibrillation (NVAF) and chronic kidney disease
- Improvements in the learnability of smartphone haptic interfaces for visually impaired users
- Role of the malic enzyme in metabolism of the halotolerant methanotroph Methylotuvimicrobium alcaliphilum 20Z
- Cyclic loading test study on a new cast-in-situ insulated sandwich concrete wall
- Natural compounds as angiogenic enzyme thymidine phosphorylase inhibitors: In vitro biochemical inhibition, mechanistic, and in silico modeling studies
- Analysis of virulence potential of Escherichia coli O145 isolated from cattle feces and hide samples based on whole genome sequencing
- Pre-clinical medical student reflections on implicit bias: Implications for learning and teaching
- Prognostic significance of non-sustained ventricular tachycardia on stored electrograms in pacemaker recipients
- Determinants of preterm birth among mothers who gave birth at public hospitals in the Amhara region, Ethiopia: A case-control study
- Real-world evidence of the effectiveness of ombitasvir-paritaprevir/r ± dasabuvir ± ribavirin in patients monoinfected with chronic hepatitis C or coinfected with human immunodeficiency virus-1 in Spain
- Unique transcriptomic landscapes identified in idiopathic spontaneous and infection related preterm births compared to normal term births
- Restrained expansion of the recall germinal center response as biomarker of protection for influenza vaccination in mice
- Arabidopsis TRM5 encodes a nuclear-localised bifunctional tRNA guanine and inosine-N1-methyltransferase that is important for growth
- Achievement of weight loss in patients with overweight during dietetic treatment in primary health care
- Autophagy deficiency exacerbates colitis through excessive oxidative stress and MAPK signaling pathway activation
- The impacts of parity on lung function data (LFD) of healthy females aged 40 years and more issued from an upper middle income country (Algeria): A comparative study
- Reorganization of spatial configurations in visual working memory: A matter of set size?
- Unravelling travellers’ route choice behaviour at full-scale urban network by focusing on representative OD pairs in computer experiments
- Evaluating the higher-order structure of the Profile of Emotional Competence (PEC): Confirmatory factor analysis and Bayesian structural equation modeling
- HIV prevalence and correlated factors among male clients of female sex workers in a border region of China
- Next generation sequencing and RNA-seq characterization of adipose tissue in the Nile crocodile (Crocodylus niloticus) in South Africa: Possible mechanism(s) of pathogenesis and pathophysiology of pansteatitis
- Association between advanced maternal age and maternal and neonatal morbidity: A cross-sectional study on a Spanish population
- Ethnic differences in the prevalence, socioeconomic and health related risk factors of knee pain and osteoarthritis symptoms in older Malaysians
- Increasing knowledge of HIV status in a country with high HIV testing coverage: Results from the Botswana Combination Prevention Project
- Friends with benefits: The effects of vegetative shading on plant survival in a green roof environment
- Comparison of the fecal, cecal, and mucus microbiome in male and female mice after TNBS-induced colitis
- Identifying candidate diagnostic markers for early stage of non-small cell lung cancer
- Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
- Correction: KML001 Induces Apoptosis and Autophagic Cell Death in Prostate Cancer Cells via Oxidative Stress Pathway
- Unique developmental trajectories of risk behaviors in adolescence and associated outcomes in young adulthood
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- Overexpression of Saussurea involucrata dehydrin gene SiDHN promotes cold and drought tolerance in transgenic tomato plants
- Foxtail millet (Setaria italica (L.) P. Beauv) CIPKs are responsive to ABA and abiotic stresses
- Autonomous drone hunter operating by deep learning and all-onboard computations in GPS-denied environments
- Heterogeneity Diffusion Imaging of gliomas: Initial experience and validation
- Frequency cluster formation and slow oscillations in neural populations with plasticity
- DHP23002 as a next generation oral paclitaxel formulation for pancreatic cancer therapy
- Diagnostic accuracy of SOX11 immunohistochemistry in mantle cell lymphoma: A meta-analysis
- Analytical solution to swing equations in power grids
- Pathways to conspiracy: The social and linguistic precursors of involvement in Reddit’s conspiracy theory forum
- Spatiotemporally random and diverse grid cell spike patterns contribute to the transformation of grid cell to place cell in a neural network model
- Empathic concern and personal distress depend on situational but not dispositional factors
- Who is more susceptible to job stressors and resources? Sensory-processing sensitivity as a personal resource and vulnerability factor
- Cost-effectiveness of integrating postpartum antiretroviral therapy and infant care into maternal & child health services in South Africa
- A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling
- One step at a time: Physical activity is linked to positive interpretations of ambiguity
- Calreticulin regulates vascular endothelial growth factor-A mRNA stability in gastric cancer cells
- Evaluation of various methods of selection of B. subtilis strains capable of secreting surface-active compounds
- Association between US Pharmacopeia (USP) monograph standards, generic entry and prescription drug costs
- Molecular characterisation of the synovial fluid microbiome in rheumatoid arthritis patients and healthy control subjects
- On sorption hysteresis in wood: Separating hysteresis in cell wall water and capillary water in the full moisture range
- Inbreeding, Allee effects and stochasticity might be sufficient to account for Neanderthal extinction
- Reliability and construct validity of the stepping-forward affordance perception test for fall risk assessment in community-dwelling older adults
- Socioeconomic determinants of nutritional status among ‘Baiga’ tribal children In Balaghat district of Madhya Pradesh: A qualitative study
- Study on characteristics of fire plume in building facade window under lateral blow
- ‘When you talk to someone in a bad way or always put her under pressure, it is actually worse than beating her’: Conceptions and experiences of emotional intimate partner violence in Rwanda and South Africa
- Effects of 6-mercaptopurine in pressure overload induced right heart failure
- The association between haemoglobin levels in the first 20 weeks of pregnancy and pregnancy outcomes
- Implementation and evaluation of an antimicrobial stewardship programme in companion animal clinics: A stepped-wedge design intervention study
- Factors associated with persistently high-cost health care utilization for musculoskeletal pain
- Nitrogen and chlorophyll status determination in durum wheat as influenced by fertilization and soil management: Preliminary results
- Effect of repeated in vivo microCT imaging on the properties of the mouse tibia
- Coupling environment and physiology to predict effects of climate change on the taxonomic and functional diversity of fish assemblages in the Murray-Darling Basin, Australia
- Hematology and plasma biochemistries in the Blanding’s turtle (Emydoidea blandingii) in Lake County, Illinois
- CRISPR-Cas influences the acquisition of antibiotic resistance in Klebsiella pneumoniae
- Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors
- Antidepressant prescriptions, discontinuation, depression and perinatal outcomes, including breastfeeding: A population cohort analysis
- Why men with a low-risk prostate cancer select and stay on active surveillance: A qualitative study
- Imported severe malaria and risk factors for intensive care: A single-centre retrospective analysis
- Combined treatment (image-guided thrombectomy and endovascular therapy with open femoral access) for acute lower limb ischemia: Clinical efficacy and outcomes
- Low-latency single channel real-time neural spike sorting system based on template matching
- Quantifying the scale effect in geospatial big data using semi-variograms
- Paper-and-pencil versus computerized administration mode: Comparison of data quality and risk behavior prevalence estimates in the European school Survey Project on Alcohol and other Drugs (ESPAD)
- Regression adjusted colocalisation colour mapping (RACC): A novel biological visual analysis method for qualitative colocalisation analysis of 3D fluorescence micrographs
- Ostrich eggshell bead diameter in the Holocene: Regional variation with the spread of herding in eastern and southern Africa
- Spatial and temporal variations in female size at maturity of a Southern Rock Lobster (Jasus edwardsii) population: A likely response to climate change
- Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells
- Training rhesus macaques to take daily oral antiretroviral therapy for preclinical evaluation of HIV prevention and treatment strategies
- Left ventricular structural and functional changes in Friedreich ataxia – Relationship with body size, sex, age and genetic severity
- Magnitude and factors associated with anemia among pregnant women attending antenatal care in Bench Maji, Keffa and Sheka zones of public hospitals, Southwest, Ethiopia, 2018: A cross -sectional study
- Effectiveness of telerehabilitation in the management of adults with stroke: A systematic review
- Hydrogen sulphide-induced hypometabolism in human-sized porcine kidneys
- Correction: Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin
- Retraction: Regulation of gastric smooth muscle contraction via Ca2+-dependent and Ca2+-independent actin polymerization
- Evaluation of neutral oral contrast agents for assessment of the small bowel at abdominal staging CT
- Blood type and breed-associated differences in cell marker expression on equine bone marrow-derived mesenchymal stem cells including major histocompatibility complex class II antigen expression
- Induced abortion and future use of IVF treatment; A nationwide register study
- Psychosocial determinants of sustained maternal functional impairment: Longitudinal findings from a pregnancy-birth cohort study in rural Pakistan
- Measurement of finger joint angle using stretchable carbon nanotube strain sensor
- Determinants of mortality among patients with drug-resistant tuberculosis in northern Nigeria
- Drugs modulating stochastic gene expression affect the erythroid differentiation process
- Efficacy of UB0316, a multi-strain probiotic formulation in patients with type 2 diabetes mellitus: A double blind, randomized, placebo controlled study
- Prognostic value of des-γ-carboxy prothrombin in patients with hepatocellular carcinoma treated with transarterial chemotherapy: A systematic review and meta-analysis
- Avermectin induces the oxidative stress, genotoxicity, and immunological responses in the Chinese Mitten Crab, Eriocheir sinensis
- Antibiotic use in mandarin production (Citrus reticulata Blanco) in major mandarin-producing areas in Thailand: A survey assessment
- Application of CPI cutoff value based on parentage testing of duos and trios typed by four autosomal kits
- Correction: Good and Bad in the Hands of Politicians: Spontaneous Gestures during Positive and Negative Speech
- Adolescents with worse levels of oral health literacy have more cavitated carious lesions
- Effective methods for the inactivation of Francisella tularensis
- Detection of early-stage Alzheimer’s pathology using blood-based autoantibody biomarkers in elderly hip fracture repair patients
- Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease
- Analysis of HER2 genomic binding in breast cancer cells identifies a global role in direct gene regulation
- Population productivity of shovelnose rays: Inferring the potential for recovery
- Correction: Long-term clinical outcomes in a cohort of patients with solitary plasmacytoma treated in the modern era
- Effects of tetracycline on myocardial infarct size in obese rats with chemically-induced colitis
- Mineral absorption is an enriched pathway in a brain region of restless legs syndrome patients with reduced MEIS1 expression
- Changes in weight and body composition across five years at university: A prospective observational study
- Adeno-associated virus-mediated expression of human butyrylcholinesterase to treat organophosphate poisoning
- Effects of insulin signaling on mouse taste cell proliferation
- Patient-level cost of home- and facility-based child pneumonia treatment in Suba Sub County, Kenya
- TAP: A static analysis model for PHP vulnerabilities based on token and deep learning technology
- Cost-effectiveness of QuantiFERON-TB Gold In-Tube versus tuberculin skin test for diagnosis and treatment of Latent Tuberculosis Infection in primary health care workers in Brazil
- Multifaceted intervention for the prevention and management of musculoskeletal pain in nursing staff: Results of a cluster randomized controlled trial
- Changes over time in creatinine clearance and comparison of emergent adverse events for HIV-positive adults receiving standard doses (300 mg/day) of lamivudine-containing antiretroviral therapy with baseline creatinine clearance of 30–49 vs ≥50 mL/min
- Population dynamics of foxes during restricted-area culling in Britain: Advancing understanding through state-space modelling of culling records
- Impacts of experimental advisory exit speed sign on traffic speeds for freeway exit ramp
- In-hospital outcomes and 30-day readmission rates among ischemic and hemorrhagic stroke patients with delirium
- Monitoring quality indicators for the Xpert MTB/RIF molecular assay in Ethiopia
- Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids
- Correction: Using remote sensing to detect whale strandings in remote areas: The case of sei whales mass mortality in Chilean Patagonia
- Comparison of the inoculum size effects of antibiotics on IMP-6 β-lactamase-producing Enterobacteriaceae co-harboring plasmid-mediated quinolone resistance genes
- Contrast-enhanced computed tomography findings of canine primary renal tumors including renal cell carcinoma, lymphoma, and hemangiosarcoma
- Non-invasive in vivo imaging of UCP1 expression in live mice via near-infrared fluorescent protein iRFP720
- Overexpression of pink1 or parkin in indirect flight muscles promotes mitochondrial proteostasis and extends lifespan in Drosophila melanogaster
- Fiber stiffness, pore size and adhesion control migratory phenotype of MDA-MB-231 cells in collagen gels
- Comparison of two experimental ARDS models in pigs using electrical impedance tomography
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- Stroke risks in women with dysmenorrhea by age and stroke subtype
- Changes in patterns of mortality rates and years of life lost due to firearms in the United States, 1999 to 2016: A joinpoint analysis
- In vitro modeling of Batrachochytrium dendrobatidis infection of the amphibian skin
- Development and validation of LC-MS/MS method for imatinib and norimatinib monitoring by finger-prick DBS in gastrointestinal stromal tumor patients
- Correction: Habitat disturbance and the organization of bacterial communities in Neotropical hematophagous arthropods
- Characterisation of early metazoan secretion through associated signal peptidase complex subunits, prohormone convertases and carboxypeptidases of the marine sponge (Amphimedon queenslandica)
- Time trends between 2002 and 2017 in correlates of self-reported sitting time in European adults
- Performance of patient acuity rating by rapid response team nurses for predicting short-term prognosis
- Changes in HbA1c during the first six years after the diagnosis of Type 2 diabetes mellitus predict long-term microvascular outcomes
- Correction: Antimicrobial resistance genotypes and phenotypes of Campylobacter jejuni isolated in Italy from humans, birds from wild and urban habitats, and poultry
- Correction: Mental health and quality of life outcomes in family members of patients with chronic critical illness admitted to the intensive care units of two Brazilian hospitals serving the extremes of the socioeconomic spectrum
- Correction: Establishing an infrastructure for collaboration in primate cognition research
- Correction: The impact of public health insurance on health care utilisation, financial protection and health status in low- and middle-income countries: A systematic review
- Health provider and service-user experiences of sensory modulation rooms in an acute inpatient psychiatry setting
- Comparison of potential drug-drug interactions with metabolic syndrome medications detected by two databases
- The Polish version of the Cultural Intelligence Scale: Assessment of its reliability and validity among healthcare professionals and medical faculty students
- Selection of optimal reference genes for qRT-PCR analysis of shoot development and graviresponse in prostrate and erect chrysanthemums
- Metastasis risk prediction model in osteosarcoma using metabolic imaging phenotypes: A multivariable radiomics model
- Defining hospital community benefit activities using Delphi technique: A comparison between China and the United States
- Establishment of the experimental procedure for prediction of conjugation capacity in mutant UGT1A1
- A robust multi-objective optimization framework to capture both cellular and intercellular properties in cardiac cellular model tuning: Analyzing different regions of membrane resistance profile in parameter fitting
- Sea star wasting disease demography and etiology in the brooding sea star Leptasterias spp.
- Diagnostic plasma miRNA-profiles for ovarian cancer in patients with pelvic mass
- Genetic diversity and drug resistance of HIV-1 among infected pregnant women newly diagnosed in Luanda, Angola
- I’ve been robbed! – Can changes in floral traits discourage bee pollination?
- Visualising statistical models using dynamic nomograms
- Assessing the capacity of Malawi’s district and central hospitals to manage traumatic diaphyseal femoral fractures in adults
- Diagnostic performance of basal cortisol level at 0900-1300h in adrenal insufficiency
- The Mastery Rubric for Bioinformatics: A tool to support design and evaluation of career-spanning education and training
- Microdissection and whole chromosome painting confirm karyotype transformation in cryptic species of the Lariophagus distinguendus (Förster, 1841) complex (Hymenoptera: Pteromalidae)
- Quality of Kangaroo Mother Care services in Ethiopia: Implications for policy and practice
- Gemcitabine potentiates the anti-tumour effect of radiation on medullary thyroid cancer
- iTRAQ-based high-throughput proteomics analysis reveals alterations of plasma proteins in patients infected with human bocavirus
- The detection of a non-anemophilous plant species using airborne eDNA
- Perception and control of low cable operation forces in voluntary closing body-powered upper-limb prostheses
- Neoadjuvant chemotherapy plus surgery versus concurrent chemoradiotherapy in stage IB2-IIB cervical cancer: A systematic review and meta-analysis
- Randomized methods to characterize large-scale vortical flow networks
- Disentangling the coexistence strategies of mud-daubing wasp species through trophic analysis in oases of Baja California peninsula
- Front-of-pack nutritional labels: Understanding by low- and middle-income Mexican consumers
- Distress in patients with end-stage renal disease: Staff perceptions of barriers to the identification of mild-moderate distress and the provision of emotional support
- Pathways to antibiotics in Bangladesh: A qualitative study investigating how and when households access medicine including antibiotics for humans or animals when they are ill
- DOC export is exceeded by C fixation in May Creek: A late-successional watershed of the Copper River Basin, Alaska
- Behavioral observation of prosocial behavior and social initiative is related to preschoolers’ psychopathological symptoms
- Evaluating the impact of citations of articles based on knowledge flow patterns hidden in the citations
- Correction: Economic sanctions and academia: Overlooked impact and long-term consequences
- Correction: A novel association between relaxin receptor polymorphism and hematopoietic stem cell yield after mobilization
- Expression of Concern: Cooperativity of Oncogenic K-Ras and Downregulated p16/INK4A in Human Pancreatic Tumorigenesis
- Price dispersion of generic medications
- Sex differences in body composition but not neuromuscular function following long-term, doxycycline-induced reduction in circulating levels of myostatin in mice
- The emotion regulation effect of cognitive control is related to depressive state through the mediation of rumination: An ERP study
- Comparison of SMS-EPI and 3D-EPI at 7T in an fMRI localizer study with matched spatiotemporal resolution and homogenized excitation profiles
- Left ventricular mass normalization for body size in children based on an allometrically adjusted ratio is as accurate as normalization based on the centile curves method
- Correction: Combining biophysical parameters, spectral indices and multivariate hyperspectral models for estimating yield and water productivity of spring wheat across different agronomic practices
- Correction: Flowers as viral hot spots: Honey bees (Apis mellifera) unevenly deposit viruses across plant species
- 'Small small quarrels bring about happiness or love in the relationships’: Exploring community perceptions and gendered norms contributing to male perpetrated intimate partner violence in the Central Region of Ghana
- The performance of practitioners conducting facial comparisons on images of children across age
- Increased amounts and stability of telomeric repeat-containing RNA (TERRA) following DNA damage induced by etoposide
- Patients with limitation or withdrawal of life supporting care admitted in a medico-surgical intermediate care unit: Prevalence, description and outcome over a six-month period
- Correction: Diverse radiofrequency sensitivity and radiofrequency effects of mobile or cordless phone near fields exposure in Drosophila melanogaster
- Predicting the performance of TV series through textual and network analysis: The case of Big Bang Theory
- Risk of temperature, humidity and concentrations of air pollutants on the hospitalization of AECOPD
- Mixed methods grant applications in the health sciences: An analysis of reviewer comments
- Renal abnormalities among children with sickle cell conditions in highly resource-limited setting in Ghana
- Size matters: How reaching and vergence movements are influenced by the familiar size of stereoscopically presented objects
- Willingness to receive institutional and community-based eldercare among the rural elderly in China
- An improved deep learning method for predicting DNA-binding proteins based on contextual features in amino acid sequences
- Beyond executive functions, creativity skills benefit academic outcomes: Insights from Montessori education
- A LAMP assay for the rapid and robust assessment of Wolbachia infection in Aedes aegypti under field and laboratory conditions
- Nonarteritic anterior ischemic optic neuropathy is associated with cerebral small vessel disease
- Fiber-tract localized diffusion coefficients highlight patterns of white matter disruption induced by proximity to glioma
- The fight against polio through the NO-DO newsreels during the Francoism period in Spain
- Ocean sound levels in the northeast Pacific recorded from an autonomous underwater glider
- Cost-consequence analysis of influenza vaccination among the staff of a large teaching hospital in Rome, Italy: A pilot study
- The relationship among the progression of inflammation in umbilical cord, fetal inflammatory response, early-onset neonatal sepsis, and chorioamnionitis
- How medical professional students view older people with dementia: Implications for education and practice
- An enhanced nonparametric EWMA sign control chart using sequential mechanism
- Land use change, carbon stocks and tree species diversity in green spaces of a secondary city in Myanmar, Pyin Oo Lwin
- Is there a difference in women’s experiences of care with medication vs. manual vacuum aspiration abortions? Determinants of person-centered care for abortion services
- Maternal complications in pregnancy and childbirth for women with epilepsy: Time trends in a nationwide cohort
- Adsorption of oxytetracycline on kaolinite
- Interdisciplinary stratified care for low back pain: A qualitative study on the acceptability, potential facilitators and barriers to implementation
- The role of resource transfer in positive, non-additive litter decomposition
- The impact of language on the interpretation of resuscitation clinical care plans by doctors. A mixed methods study
- Quantum dots reveal heterogeneous membrane diffusivity and dynamic surface density polarization of dopamine transporter
- Genomic analysis of Shiga toxin-producing Escherichia coli from patients and asymptomatic food handlers in Japan
- The heavy metals lead and cadmium are cytotoxic to human bone osteoblasts via induction of redox stress
- Anatomical, taxonomic, and phylogenetic reappraisal of a poorly known ghost knifefish, Tembeassu marauna (Ostariophysi: Gymnotiformes), using X-ray microcomputed tomography
- Matrix-assisted laser desorption/ionization time of flight mass spectrometry identification of Vibrio (Listonella) anguillarum isolated from sea bass and sea bream
- Recommendations of older adults on how to use the PROM ‘TOPICS-MDS’ in healthcare conversations: A Delphi study
- The winner takes it all—Competitiveness of single nodes in globalized supply networks
- Hamsters in the city: A study on the behaviour of a population of common hamsters (Cricetus cricetus) in urban environment
- Correction: Liquid biopsies for omics-based analysis in sentinel mussels
- Size matters! Association between journal size and longitudinal variability of the Journal Impact Factor
- Drug resistance and epidemiology characteristics of multidrug-resistant tuberculosis patients in 17 provinces of China
- A model-based framework for chronic hepatitis C prevalence estimation
- Adding rewards to regulation: The impacts of watershed conservation on land cover and household wellbeing in Moyobamba, Peru
- Clinical determinants of social media use in individuals with schizophrenia
- Arsenic and nutrient absorption characteristics and antioxidant response in different leaves of two ryegrass (Lolium perenne) species under arsenic stress
- An evolution of socioeconomic related inequality in teenage pregnancy and childbearing in Malawi
- A single plasmid based CRISPR interference in Synechocystis 6803 – A proof of concept
- Structural vulnerability to narcotics-driven firearm violence: An ethnographic and epidemiological study of Philadelphia’s Puerto Rican inner-city
- Temporal trends in intracerebral hemorrhage: Evidence from the Austrian Stroke Unit Registry
- Prevalence and risk factors for multi-drug resistant Escherichia coli among poultry workers in the Federal Capital Territory, Abuja, Nigeria
- Prediction of disease-related metabolites using bi-random walks
- Clinical use, efficacy, and durability of maraviroc for antiretroviral therapy in routine care: A European survey
- Biomarker discovery in inflammatory bowel diseases using network-based feature selection
- The Cinderella Complex: Word embeddings reveal gender stereotypes in movies and books
- Exoproteome profiling of Trypanosoma cruzi during amastigogenesis early stages
- Reproducible phenotype alteration due to prolonged cooling of the pupae of Polyommatus icarus butterflies
- Nutritional treatment with an immune-modulating enteral formula alleviates 5-fluorouracil-induced adverse effects in rats
- Pharmacy-based predictors of non-adherence, non-persistence and reinitiation of antihypertensive drugs among patients on oral diabetes drugs in the Netherlands
- Systematic review of the accuracy of plasma preparation tubes for HIV viral load testing
- Circadian clock regulates the shape and content of dendritic spines in mouse barrel cortex
- “Anybody can make kids; it takes a real man to look after your kids”: Aboriginal men’s discourse on parenting
- Correction: A 1D computer model of the arterial circulation in horses: An important resource for studying global interactions between heart and vessels under normal and pathological conditions
- Maternal interpregnancy weight change and premature birth: Findings from an English population-based cohort study
- Correction: Identifying performance benchmarks and determinants for reproductive performance and calf survival using a longitudinal field study of cow-calf herds in western Canada
- Prognostic value of the model for end-stage liver disease excluding INR score (MELD-XI) in patients with adult congenital heart disease
- Treatment of Urethral Pain Syndrome (UPS) in Sweden
- Migration and political polarization in the U.S.: An analysis of the county-level migration network
- Epidemiology and complications of late-onset sepsis: an Italian area-based study
- The relationship between women’s experience of intimate partner violence and other socio-demographic factors, and under-5 children’s health in South Africa
- Association between trunk and gluteus muscle size and long jump performance
- Multimorbidity and complex multimorbidity in Brazilian rural workers
- Correction: Interspecific Phylogenic Relationships within Genus Melilotus Based on Nuclear and Chloroplast DNA
- Insulin-like growth factor (IGF)-II- mediated fibrosis in pathogenic lung conditions
- Wolf diet and prey selection in the South-Eastern Carpathian Mountains, Romania
- In vitro activity of aryl-thiazole derivatives against Schistosoma mansoni schistosomula and adult worms
- Sample size issues in multilevel logistic regression models
- Seed germination ecology of Ageratum houstonianum: A major invasive weed in Nepal
- Experiences of lifestyle change among women with gestational diabetes mellitus (GDM): A behavioural diagnosis using the COM-B model in a low-income setting
- Pharmacologic management of HCV treatment in patients with HCV monoinfection vs. HIV/HCV coinfection: Does coinfection really matter?
- The association between cigarette smoking and serum thyroid stimulating hormone, thyroid peroxidase antibodies and thyroglobulin antibodies levels in Chinese residents: A cross-sectional study in 10 cities
- Mouse movement measures enhance the stop-signal task in adult ADHD assessment
- Ecosystem functioning in urban grasslands: The role of biodiversity, plant invasions and urbanization
- Correction: KETOS: Clinical decision support and machine learning as a service – A training and deployment platform based on Docker, OMOP-CDM, and FHIR Web Services
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- Hyperconnectivity during screen-based stories listening is associated with lower narrative comprehension in preschool children exposed to screens vs dialogic reading: An EEG study
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- In vitro endothelial cell migration from limbal edge-modified Quarter-DMEK grafts
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- Complete Chloroplast Genomes of Vachellia nilotica and Senegalia senegal: Comparative Genomics and Phylogenomic Placement in a New Generic System
- Retraction: Over-Expression of Superoxide Dismutase Ameliorates Cr(VI) Induced Adverse Effects via Modulating Cellular Immune System of Drosophila melanogaster
- Effect of pre-season training phase on anthropometric, hormonal and fitness parameters in young soccer players
- Exosomes from conditioned media of bone marrow-derived mesenchymal stem cells promote bone regeneration by enhancing angiogenesis
- Outcome of patients with heart failure after transcatheter aortic valve implantation
- Fatty acid profile of Romanian’s common bean (Phaseolus vulgaris L.) lipid fractions and their complexation ability by β-cyclodextrin
- Appropriate empirical antibiotic therapy and mortality: Conflicting data explained by residual confounding
- Treatment of corneal endothelial damage in a rabbit model with a bioengineered graft using human decellularized corneal lamina and cultured human corneal endothelium
- Telbivudine on IgG-associated hypergammaglobulinemia and TGF-β1 hyperactivity in hepatitis B virus-related liver cirrhosis
- Correction: Axial variation of deoxyhemoglobin density as a source of the low-frequency time lag structure in blood oxygenation level-dependent signals
- Correction: Mobile health-based physical activity intervention for individuals with spinal cord injury in the community: A pilot study
- Retraction: Placental expression of CD100, CD72 and CD45 is dysregulated in human miscarriage
- Correction: Use of IoT sensing and occupant surveys for determining the resilience of buildings to forest fire generated PM2.5
- Correction: The modulation of facial mimicry by attachment tendencies and their underlying affiliation motives in 3-year-olds: An EMG study
- Correction: Cognitive impairment in multiple sclerosis: An exploratory analysis of environmental and lifestyle risk factors
- Discovering novel disease comorbidities using electronic medical records
- Glutathione contributes to efficient post-Golgi trafficking of incoming HPV16 genome
- Epidemiology and antimicrobial resistance of methicillin-resistant Staphylococcus aureus isolates colonizing pigs with different exposure to antibiotics
- Social information use in adolescents: The impact of adults, peers and household composition
- Public practices on antibiotic use: A cross-sectional study among Qatar University students and their family members
- Effects of Topper Training on psychosocial problems, self-esteem, and peer victimisation in Dutch children: A randomised trial
- Comparative studies of two generations of NanoString nCounter System
- General practitioners’ perceptions of delayed antibiotic prescription for respiratory tract infections: A phenomenographic study
- Can altered magnetic field affect the foraging behaviour of ants?
- Parasitic infections and medical expenses according to Health Insurance Review Assessment claims data in South Korea, 2011–2018
- A prospective observational study of on-treatment plasma homocysteine levels as a biomarker of toxicity, depression and vitamin supplementation lead-in time pre pemetrexed, in patients with non-small cell lung cancer and malignant mesothelioma
- A strategy to identify protein-N-myristoylation-dependent phosphorylation reactions of cellular proteins by using Phos-tag SDS-PAGE
- Expression profile of sonic hedgehog signaling-related molecules in basal cell carcinoma
- Seasonal alternation of the ontogenetic development of the moon jellyfish Aurelia coerulea in Maizuru Bay, Japan
- Reliability of measurement of active trunk movement in wheelchair basketball players
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- Determining an optimal pool size for testing beef herds for Johne’s disease in Australia
- Correction: Change in larval fish assemblage in a USA east coast estuary estimated from twenty-six years of fixed weekly sampling
- APOE-knockout in rabbits causes loss of cells in nucleus pulposus and enhances the levels of inflammatory catabolic cytokines damaging the intervertebral disc matrix
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- A daily diary study on maladaptive daydreaming, mind wandering, and sleep disturbances: Examining within-person and between-persons relations
- Improved chemotherapy modeling with RAG-based immune deficient mice
- Effect of tracheal antimicrobial peptide on the development of Mannheimia haemolytica pneumonia in cattle
- The internal realities of individuals with type 2 diabetes – a functional framework of self-management practices via Grounded Theory approach
- Role of platelet parameters in early detection and prediction of severity of preeclampsia: A comparative cross-sectional study at Ayder comprehensive specialized and Mekelle general hospitals, Mekelle, Tigray, Ethiopia
- eIF4E and 4EBP1 are prognostic markers of head and neck squamous cell carcinoma recurrence after definitive surgery and adjuvant radiotherapy
- Smoking and other determinants of bone turnover
- Oxygen delivery, oxygen consumption and decreased kidney function after cardiopulmonary bypass
- School engagement of children in early grades: Psychometric, and gender comparisons
- Correction: A review of the elusive bicolored iris Snouted Treefrogs (Anura: Hylidae:Scinax uruguayus group)
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- Discovery of stable and prognostic CT-based radiomic features independent of contrast administration and dimensionality in oesophageal cancer
- Correction: Population-based dementia prediction model using Korean public health examination data: A cohort study
- Location, location, location: Close ties among older continuing care retirement community residents
- Correction: ISED: Constructing a high-resolution elevation road dataset from massive, low-quality in-situ observations derived from geosocial fitness tracking data
- Correction: Use of validated objective methods of locomotion characteristics and weight distribution for evaluating the efficacy of ketoprofen for alleviating pain in cows with limb pathologies
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- Correction: Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing
- Genetic diversity and antiretroviral resistance-associated mutation profile of treated and naive HIV-1 infected patients from the Northwest and Southwest regions of Cameroon
- Maximum parsimony interpretation of chromatin capture experiments
- Multiple innate antibacterial immune defense elements are correlated in diverse ungulate species
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- First evidence of hepatitis E virus infection in a small mammal (yellow-necked mouse) from Croatia
- The inhibitory effects of polypyrrole on the biofilm formation of Streptococcus mutans
- Self-reported adverse drug effects and associated factors among H. pylori infected patients on standard triple therapy: Prospective follow up study
- Upregulation of ERK phosphorylation in rat dorsal root ganglion neurons contributes to oxaliplatin-induced chronic neuropathic pain
- Characterization of the relationship between neutron production and thermal load on a target material in an accelerator-based boron neutron capture therapy system employing a solid-state Li target
- Remote heart rate monitoring - Assessment of the Facereader rPPg by Noldus
- Seroprevalence of rubella virus antibodies among pregnant women in the Center and South-West regions of Cameroon
- Effectiveness of steam sterilization of reusable medical devices in primary and secondary care public hospitals in Nepal and factors associated with ineffective sterilization: A nation-wide cross-sectional study
- Relevance of HTLV-1 proviral load in asymptomatic and symptomatic patients living in endemic and non-endemic areas of Argentina
- Ritualized aggressive behavior reveals distinct social structures in native and introduced range tawny crazy ants
- The value of kinetic glomerular filtration rate estimation on medication dosing in acute kidney injury
- Screening and characterization of long noncoding RNAs involved in the albinism of Ananas comosus var. bracteatus leaves
- Visual attention to emotional faces in adolescents with social anxiety disorder receiving cognitive behavioral therapy
- A Q fever outbreak associated to courier transport of pets
- Antibodies against measles and rubella virus among different age groups in Thailand: A population-based serological survey
- Molecular diet analysis of Anguilliformes leptocephalus larvae collected in the western North Pacific
- Correction: The relationship between context, structure, and processes with outcomes of 6 regional diabetes networks in Europe
- Correction: The C-reactive protein/albumin ratio as an independent predictor of mortality in patients with severe sepsis or septic shock treated with early goal-directed therapy
- Interleukin 21 (IL-21) regulates chronic allograft vasculopathy (CAV) in murine heart allograft rejection
- Semantic computational analysis of anticoagulation use in atrial fibrillation from real world data
- The implementation of HTA in medicine pricing and reimbursement policies in Indonesia: Insights from multiple stakeholders
- International experiences during United States ophthalmology residency training: Current structure of international experiences and perspectives of faculty mentors at United States training institutions
- Questionable utility of digoxin in left-ventricular assist device recipients: A multicenter, retrospective analysis
- Genotyping and outcomes of presumptive second line ART failure cases switched to third line or maintained on second line ART in Mumbai, India
- A mathematical model of honey bee colony dynamics to predict the effect of pollen on colony failure
- Airway microbiome composition correlates with lung function and arterial stiffness in an age-dependent manner
- An odorant receptor from Anopheles gambiae that demonstrates enantioselectivity to the plant volatile, linalool
- Factors associated with full immunization of children 12–23 months of age in Ethiopia: A multilevel analysis using 2016 Ethiopia Demographic and Health Survey
- Additional evidence that the rat renal interstitium contracts in vivo
- Factors affecting acceptance of at-birth point of care HIV testing among providers and parents in Kenya: A qualitative study
- Removal efficiency of central vacuum system and protective masks to suspended particles from dental treatment
- Psychological well-being and distress in patients with generalized anxiety disorder: The roles of positive and negative functioning
- Conventional rotator cuff versus all-suture anchors—A biomechanical study focusing on the insertion angle in an unlimited cyclic model
- Are viral-infections associated with Ménière’s Disease? A systematic review and meta-analysis of molecular-markers of viral-infection in case-controlled observational studies of MD
- An evaluation of genetic causes and environmental risks for bilateral optic atrophy
- Comparative vector competence of the Afrotropical soft tick Ornithodoros moubata and Palearctic species, O. erraticus and O. verrucosus, for African swine fever virus strains circulating in Eurasia
- Effects of the solubility of yeast cell wall preparations on their potential prebiotic properties in dogs
- Carbogen gas-challenge BOLD fMRI in assessment of liver hypoxia after portal microcapsules implantation
- Socioeconomic determinants of cancer screening utilisation in Latin America: A systematic review
- Development of an easy-to-use questionnaire assessing critical care nursing competence in Japan: A cross-sectional study
- Towards successful business process improvement – An extension of change acceleration process model
- Correction: Dietary polyphenols as a safe and novel intervention for modulating pain associated with intervertebral disc degeneration in an in-vivo rat model
- Correction: Phylogenetic analysis of hepatitis C virus among HIV/ HCV co-infected patients in Nigeria
- Correction: Relationship between self-disclosure to first acquaintances and subjective well-being in people with schizophrenia spectrum disorders living in the community
- Impact of ATM rs1801516 on late skin reactions of radiotherapy for breast cancer: Evidences from a cohort study and a trial sequential meta-analysis
- Involvement of human and canine MRP1 and MRP4 in benzylpenicillin transport
- Soil organic matter rather than ectomycorrhizal diversity is related to urban tree health
- Clinical risk assessment in early pregnancy for preeclampsia in nulliparous women: A population based cohort study
- The relation between circulating levels of vitamin D and parathyroid hormone in children and adolescents with overweight or obesity: Quest for a threshold
- Behavioural evidence for segments as subordinate units in Chinese spoken word production: The form-preparation paradigm revisited
- Correction: Measuring the impact of an interdisciplinary learning project on nursing, architecture and landscape design students’ empathy
- Analysis of the characteristics of chemotherapy-resistant renal cell carcinomas based on global transcriptional analysis of their tissues and cell lines
- The characteristics and treatment patterns of patients with Parkinson’s disease in the United States and United Kingdom: A retrospective cohort study
- Sex differences in youth elite swimming
- Unconventional SCCmec types and low prevalence of the Panton-Valentine Leukocidin exotoxin in South African blood culture Staphylococcus aureus surveillance isolates, 2013-2016
- Prosocial perceptions of taxation predict support for taxes
- Correction: Clonality analysis of pulmonary tumors by genome-wide copy number profiling
- Improved oxygenation following methylprednisolone therapy and survival in paediatric acute respiratory distress syndrome
- Normative values for relative schoolbag weight in primary school children aged 6-14 from Czech Republic: A pilot study
- Correction: Intensive longitudinal modelling predicts diurnal activity of salivary alpha-amylase
- Correction: SNV discovery and functional candidate gene identification for milk composition based on whole genome resequencing of Holstein bulls with extremely high and low breeding values
- Monoclonal antibody anti-PBP2a protects mice against MRSA (methicillin-resistant Staphylococcus aureus) infections
- Diurnal variations of amplitude of accommodation in different age groups
- HHIP overexpression inhibits the proliferation, migration and invasion of non-small cell lung cancer
- Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood–brain-barrier permeability
- Correlation analysis of cold-related gene expression with physiological and biochemical indicators under cold stress in oil palm
- Student engagement and wellbeing over time at a higher education institution
- Gender-based differences in platelet function and platelet reactivity to P2Y12 inhibitors
- Influence of season and social context on male giant panda (Ailuropoda melanoleuca) vocal behaviour
- Development of an intravaginal ring for the topical delivery of Aurora kinase A inhibitor, MLN8237
- Differential phosphorylation determines the repressor and activator potencies of GLI1 proteins and their efficiency in modulating the HPV life cycle
- Polymorphisms of FDPS, LRP5, SOST and VKORC1 genes and their relation with osteoporosis in postmenopausal Romanian women
- Depression increases the risk of rotator cuff tear and rotator cuff repair surgery: A nationwide population-based study
- Interleukin-38 interacts with destrin/actin-depolymerizing factor in human keratinocytes
- Correction: Fast, quantitative, murine cardiac 19F MRI/MRS of PFCE-labeled progenitor stem cells and macrophages at 9.4T
- Persistent post-discharge opioid prescribing after traumatic brain injury requiring intensive care unit admission: A cross-sectional study with longitudinal outcome
- Genome-wide histone modification profiling of inner cell mass and trophectoderm of bovine blastocysts by RAT-ChIP
- Aerobic exercise increases post-exercise exogenous protein oxidation in healthy young males
- Selection for tandem stop codons in ciliate species with reassigned stop codons
- Research ethics in inter- and multi-disciplinary teams: Differences in disciplinary interpretations
- Correction: Analyzing data from the digital healthcare exchange platform for surveillance of antibiotic prescriptions in primary care in urban Kenya: A mixed-methods study
- Correction: People making deontological judgments in the Trapdoor dilemma are perceived to be more prosocial in economic games than they actually are
- LFRET, a novel rapid assay for anti-tissue transglutaminase antibody detection
- Effects of isotemporal substitution of sedentary behavior with light-intensity or moderate-to-vigorous physical activity on cardiometabolic markers in male adolescents
- Topical estrogen application to wounds promotes delayed cutaneous wound healing in 80-week-old female mice
- Correction: An international randomised placebo-controlled trial of a four-component combination pill (“polypill”) in people with raised cardiovascular risk
- Correction: Evaluation of lung toxicity risk with computed tomography ventilation image for thoracic cancer patients
- Retraction: Pathological Roles of Interleukin-22 in the Development of Recurrent Hepatitis C after Liver Transplantation
- Correction: Elevational Distribution and Ecology of Small Mammals on Tanzania's Second Highest Mountain
- Correction: Decreased breast cancer-specific mortality risk in patients with a history of thyroid cancer
- Correction: Fecal microbiota dysbiosis in macaques and humans within a shared environment
- Correction: The center of pressure and ankle muscle co-contraction in response to anterior-posterior perturbations
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