Sonographic measurement of normal common bile duct diameter and associated factors at the University of Gondar comprehensive specialized hospital and selected private imaging center in Gondar town, North West Ethiopia


Autoři: Misganaw Gebrie Worku aff001;  Engdaw Fentahun Enyew aff001;  Zerubabel Tegegne Desita aff002;  Abebe Muche Moges aff001
Působiště autorů: Department of Human Anatomy, University of Gondar, College of Medicine and Health Science, School of Medicine, Gondar, Ethiopia aff001;  Department of Radiology, University of Gondar, college of Medicine and Health Science, School of Medicine, Gondar, Ethiopia aff002
Vyšlo v časopise: PLoS ONE 15(1)
Kategorie: Research Article
doi: 10.1371/journal.pone.0227135

Souhrn

Background

The biliary tree is a three-dimensional system of channels that bile flows from the hepatocytes to the gallbladder and to the intestine. Size of the common bile duct (CBD) is a predictor of biliary obstruction and, therefore, its measurement is an important component of biliary system evaluation. Factors like age, height, weight, BMI, previous cholecystectomy, drugs, and type of imaging modality affect CBD diameter, but the duct significantly dilated due to obstructive biliary pathology.

Objective

To measure the normal CBD diameter and its association with age, sex, and anthropometric measurement at the University of Gondar Comprehensive Specialized Hospital and selected private imaging center, Gondar town, Northwest Ethiopia, 2019.

Methods and materials

Institutional based cross-sectional study was conducted on 206 subjects without any history of hepatobiliary abnormality. The CBD measured at the proximal part just caudal to the porta hepatis. Descriptive analysis, student t-test, one way ANOVA, correlation and both bivariable and multivariable linear regression analysis were implemented. In bivariable linear regression variables with p-value, less than 0.2 were selected for multivariable analysis and in multivariable linear regression analysis variables with P-Value less than 0.05 were considered as statistically significant.

Results

The mean age of the study participants was 39.4 (range 18–87). The mean diameter of the CBD was 3.64mm 95%CI (3.52, 3.77), which ranges from 1.8 to 5.9 mm, with 65% of the participant having CBD diameter less than 4mm. The diameter of CBD significantly associated with age with a linear trend. The mean diameter in a rural area was greater than subjects living in an urban area. Independent t-test showed no statistically significant difference in CBD diameter between male and female subjects.

Conclusion

The lower limit of the CBD diameter for this study was similar to most of the studies, but the upper limit was found to be slightly lower. The diameter was significantly associated with age along the linear trend and it was progressively increased from the lower age group onwards. The diameter of CBD did not show statistically significant association with any of the anthropometric measurement.

Klíčová slova:

Age groups – Anthropometry – Arteries – Bile ducts – Body mass index – Linear regression analysis – Portal veins – Ultrasound imaging


Zdroje

1. Keith L, Arthur F, Anne M. Clinically Oriented anatomy, anatomy of biliary tree. Seventh Edition. Canada Toronto Ontario; 2014. .888–891.

2. Standing s. gray’s anatomy, basis of clinical practice. 40th ed. London; 2008. 1177–81 p.

3. Mohammed Mazareq SH. Measurement of Normal Common Bile Duct Diameter using Ultrasonography: The National Ribat University; 2018.

4. Behan M, Kazam E. Sonography of the common bile duct: value of the right anterior oblique view. American Journal of Roentgenology. 1978 Apr; 130(4):701–9. doi: 10.2214/ajr.130.4.701 205124

5. Admassie D. Ultrasound assessment of common bile duct diameter. Ethiop Med J. 2008; 46(4):391–5. 19271404

6. Bruno M, Brizzi RF, Mezzabotta L, Carucci P, Elia C, Gaia S, et al. Unexplained Common Bile Duct Dilatation With Normal Serum Liver Enzymes: Diagnostic Yield of Endoscopic Ultrasound and Follow-up of This Condition. Journal of Clinical Gastroenterology. 2014 Sep; 48(8):e67–70. doi: 10.1097/MCG.0b013e3182a8848a 24045275

7. Lal N. Ultrasonographic Measurement of Normal Common Bile Duct Diameter and its Correlation with Age, Sex and Anthropometry. Journal of clinical and diagnostic research. 2014; 8(12).

8. Adibi A, Givechian B. Diameter of common bile duct: what are the predicting factors? | Adibi | Journal of Research in Medical Sciences. JRMS 2007; 12(3): 121–124.

9. HOSSEIN MAHOUR G. The Common Bile Duct in Man: Its Diameter and Circumference. Annals of Surgery. 1967; 165(3).

10. Yeh BM, Liu PS, Soto JA, Corvera CA, Hussain HK. MR Imaging and CT of the Biliary Tract. Radiographic. 2009 Oct; 29(6):1669–88.

11. Cooperberg PL, Li D, Wong P, Cohen MM, Burhenne HJ. Accuracy of common hapatic duct size in the evaluation of extrahepatic biliary obstruction. Radiology. 1980 Apr; 135(1):141–4. doi: 10.1148/radiology.135.1.7360952 7360952

12. CC W, YH H, CY C. Effect of aging on common bile duct diameter: a real-time ultrasonographic study. J Clin Ultrasound. 1984; 12(8):473–8. doi: 10.1002/jcu.1870120804 6436325

13. Mohammad H MH. Sonographic Assessment of Common Bile Duct Diameter among Adults in North Central Nigeria. IOSR Journal of Dental and Medical Sciences. 2013; 6(2):32–4.

14. Bachar GN, Belenky A, Gideon S. Effect of Aging on the Adult Extrahepatic Bile Duct. J Ultrasound Med. 2003; 879–82. doi: 10.7863/jum.2003.22.9.879 14510259

15. Khan LF, Naushaba H, Parash MTH, Qasim R, Tabriz S-E-. Study of Internal Diameter of the Common Bile Duct in Human Cadaver. Bangladesh Journal of Anatomy. 2013 Jul 22; 10(1):23–6.

16. Kratzer W, Wahl S, Vonend C, Schmidt S, Öztürk S, Hänle M, et al. Caliber of the common bile duct: effect of cholecystectomy and other factors in a ultrasonographic study of 8534 patients. Zeitschrift für Gastroenterologie. 2015 Oct 19; 53(10):1161–6. doi: 10.1055/s-0034-1399476 26480051

17. Wachsberg RH. Respiratory variation of extrahepatic bile duct diameter during ultrasonography. J Ultrasound Med. 1994 Aug; 13(8):617–21. doi: 10.7863/jum.1994.13.8.617 7933030

18. Cooperberg PL. High-Resolution Real-time Ultrasound in the Evaluation of the Normal and Obstructed Biliary Tract1. Radiology. 1978; 129:477–80. doi: 10.1148/129.2.477 704864


Článek vyšel v časopise

PLOS One


2020 Číslo 1