Common mental illness among epilepsy patients in Bahir Dar city, Ethiopia: A cross-sectional study


Autoři: Minale Tareke aff001;  Minychil Birehanu aff002;  Desalegne Amare aff002;  Andargie Abate aff002
Působiště autorů: Psychiatry Department, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia aff001;  Nursing Department, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia aff002
Vyšlo v časopise: PLoS ONE 15(1)
Kategorie: Research Article
doi: 10.1371/journal.pone.0227854

Souhrn

Background

Common mental illness has a substantial impact on seizure control and negatively affects the overall quality of life among individuals with epilepsy. However, there is a dearth of studies that examined the associated factors of common mental illness among epilepsy patients in Ethiopia, particularly in the study area. This study aimed to assess the magnitude and factors associated with common mental disorders in epilepsy patients who attended government health institutions in Bahir Dar city, Ethiopia.

Method

Health institution based cross-sectional study was conducted using a systematic sampling technique among people living with epilepsy in Bahir Dar City Administration. Common mental illness was assessed using a self-reporting questionnaire and a semi-structured questionnaire was employed to collect data on socio-demographic and clinical related characteristics. Data were analyzed using descriptive statistics, univariate logistic regression, and multivariable logistic regression.

Results

The magnitude of comorbid common mental illness among people living with epilepsy was found 35.4%. High magnitude of common mental illness was reported among females (39.9%) when compared to males (32.3%). The most prevalent common mental disorders symptoms include being worried, unhappy feeling, trouble thinking clearly, and difficult to enjoy daily activities. Family history of epilepsy, frequent seizures attacks, side effects of antiepileptic drugs, lack of social support and not adherent to antiepileptic drugs were factors associated with common mental illness.

Conclusions

Common mental illness was found to be prevalent among people living with epilepsy. Therefore, it is recommended that great attention should be given to mental illness besides controlling seizure attacks.

Klíčová slova:

Adverse reactions – Depression – Drug adherence – Drug administration – Epilepsy – Ethiopia – Mental health and psychiatry – Quality of life


Zdroje

1. WHO. Epilepsy in the WHO eastern Mediterranean region: Bridging the gap. 2010.

2. Mula M. Neuropsychiatric Symptoms of Epilepsy. Switzerland Springer International Publishing; 2016. 387 p.

3. MF BEAR, CONNORS BW, PARADISO MA. NEUROSCIENCE: EXPLORING THE BRAIN. FOURTH EDITION ed: Wolters Kluwer; 2016. 650–60 p.

4. Tawar S, Bhatia S, Ilankumaran M. Mental health, are we at risk?. Indian J Community Med 2014;39(1):43–6. doi: 10.4103/0970-0218.126359 24695680

5. Association AP. Diagnostic and Statistical Manual of Mental Disorders. Fifth Edition ed. Washington, D.C: American Psychiatric Association; 2013.

6. WHO. Global burden of mental disorders and the need for a comprehensive, coordinated response from health and social sectors at the country level. 2011:1–6.

7. Keezer MR, Sisodiya SM, Sander JW. Co morbidities of epilepsy: current concepts and future perspectives. Lancet Neurol. 2015:1–10.

8. Mula M. Treatment issues for psychiatric comorbidities of epilepsy. Clin Pract. 2013;10(3):293–9.

9. Sezibera V, Nyirasafari D. Incidence of depression in Epilepsy patients. Rwanda Journal, Series F: Health Sciences. 2013;1(1):67–77.

10. Barr WB, Morrison C. Clinical Handbooks in Neuropsychology of Epilepsy. New York Springer Science+Business Media; 2015. 224–35 p.

11. Fiest KM, Patten SB, Jetté N. Screening for Depression and Anxiety in Epilepsy. Neurol Clin 2015:1–11. doi: 10.1016/j.ncl.2014.09.010

12. WHO. A user's guide to the self Reporting Questionnaire (SRQ). Geneva, Switzerland. 1994.

13. Hanlon C, Medhin G, Alem A, Araya M, Abdulahi A, Hughes M, et al. Detecting perinatal common mental disorders in Ethiopia: Validation of the self-reporting questionnaire and Edinburgh Postnatal Depression Scale. Journal of Affective Disorders. 2008;108:251–62. doi: 10.1016/j.jad.2007.10.023 18055019

14. MOGGA S, PRINCE M, ALEM A, KEBEDE D, STEWART R, GLOZIER N, et al. Outcome of major depression in Ethiopia. B R I T IS H J O UR N A L O F P SYC HIAT RY 2006;189:2 4 1–2 4 6

15. Hanlon C, Medhin G, Alem A, Araya M, Abdulahi A, Tomlinson M, et al. Sociocultural practices in Ethiopia: association with onset and persistence of postnatal common mental disorders. The British Journal of Psychiatry 2010;197:468–75. doi: 10.1192/bjp.bp.109.076497 21119153

16. Gelaye B, Lemma S, Deyassa N, Bahretibeb Y, Tesfaye M, Berhane Y, et al. Prevalence and Correlates of Mental Distress Among Working Adults in Ethiopia. Clinical Practice & Epidemiology in Mental Health. 2012;8:126–33.

17. Dessie Y, Ebrahim J, Awoke T. Mental distress among university students in Ethiopia: a cross sectional survey. Pan African Medical Journal. 2013;15(95).

18. Zeleke W, Minaye A, Kanyongo GY. Mental Health and Somatic Distress among Ethiopian Migrant Returnees from the Middle East. Int J Ment Health Psychiatry 2015;1(2):1–6.

19. ALEM A. Prevalence of mental distress in the outpatient clinic of a specialized leprosy hospital. Addis Ababa, Ethiopia, 2002. Lepr Rev. 2004;75:367–75. 15682974

20. Selamawit Z, Nurilign A. Common mental disorder among HIV infected individuals at Comprehensive HIV Care and Treatment Clinic of Debre Markos referral Hospital, Ethiopia. Journal of AIDS and Clinical Research. 2015;6(2).

21. Melese B, Bayu B, Wondwossen F, Tilahun K, Lema S, Ayehu M, et al. Prevalence of mental distress and associated factors among Hawassa University medical students, Southern Ethiopia: a cross-sectional study. BMC research notes. 2016;9(1):485. doi: 10.1186/s13104-016-2289-7 27821143

22. Getinet Alemu W, Dessalegn Malefiya Y, Boru Bifftu B. Mental Distress among Patients Admitted in Gondar University Hospital: A Cross Sectional Institution Based Study. Health Science Journal. 2016;10(6).

23. Baskind R, Birbeck GL. Epilepsy-associated stigma in sub-Saharan Africa:The social landscape of a disease. Epilepsy Behav 2005;7:68–73. doi: 10.1016/j.yebeh.2005.04.009 15978874

24. Domínguez-Aguilera MC, Muniz-Landeros ˜ CE. Prevalence of psychiatric disorders in patients with epilepsy in a tertiary level care hospital: Detection through the MINI PLUS International Structured Interview. Medicina Universitaria. 2017.

25. Amruth G, Praveen-kumar S, Nataraju B, Kasturi P. Study of psychiatric comorbidities in epilepsy by using the Mini International Neuropsychiatric Interview. Epilepsy & Behavior 2014;33:94–100.

26. Alsaadi T, El Hammasi K, Shahrour TM, Shakra M, Turkawi L, Almaskari B, et al. Prevalence of depression and anxiety among patients with epilepsy attending the epilepsy clinic at Sheikh Khalifa Medical City, UAE: A cross-sectional study. Epilepsy & Behavior. 2015;52:194–9.

27. Mbewe EK, Uys LR, Nkwanyana NM, Birbeck GL. A primary healthcare screening tool to identify depression and anxiety disorders among people with epilepsy in Zambia. Epilepsy & Behavior. 2013;27(2):296–300.

28. Bragatti JA, Torres CM, Londero RG, Assmann JB, Fontana V, Martin KC, et al. Prevalence of psychiatric comorbidities in temporal lobe epilepsy: the value of structured psychiatric interviews. Epileptic disorders. 2010;12(4):283–91. doi: 10.1684/epd.2010.0345 21112827

29. Rani R, Arora R, Dass Garg P, Bala N, Neki NS. Prevalence of psychiatric comorbidities among the patients of epilepsy attending general hospital psychiatric unit. Int J Curr Res Med Sci 2018;4(5):90–6.

30. Altınöz AE, Meriç OT, Altınöz ŞT, Eşsizoğlu A, Coşar B. Psychiatric disorders comorbid with epilepsy in a prison sample. Seizure. 2016;40:133–5. doi: 10.1016/j.seizure.2016.06.016 27423133

31. Henning O, Nakken K. Psychiatric comorbidity and use of psychotropic drugs in epilepsy patients. Acta Neurologica Scandinavica. 2010;122:18–22.

32. Swinkels WA, Kuyk JV, Van Dyck R, Spinhoven PH. Psychiatric comorbidity in epilepsy. Epilepsy & Behavior. 2005;7(1):37–50.

33. Lacey CJ, Salzberg MR, Roberts H, Trauer T, D’Souza WJ. Psychiatric comorbidity and impact on health service utilization in a community sample of patients with epilepsy. Epilepsia. 2009;50(8):1991–4. doi: 10.1111/j.1528-1167.2009.02165.x 19490049

34. Henning O, Nakken K. Psychiatric comorbidity and use of psychotropic drugs in epilepsy patients. Acta Neurologica Scandinavica. 2010;122(s190):18–22.

35. M’bayo T, Tomek M, Kamara C, Radcliffe Lisk D. Psychiatric comorbidity in African patients with epilepsy–Experience from Sierra Leone. Int J Epilepsy. 2017;61:1–5. doi: 10.1016/j.ijep.2016.12.002

36. Fekadu A, Medhin G, Selamu M, Hailemariam M, Alem A, Giorgis TW, et al. Population level mental distress in rural Ethiopia. BMC psychiatry. 2014;14(1):194.

37. Josephson CB, Jetté N. Psychiatric comorbidities in epilepsy. International Review of Psychiatry. 2017.

38. Verrotti A, Carrozzino D, Milioni M, Minna M, Fulcheri M. Epilepsy and its main psychiatric comorbidities in adults and children. Journal of the neurological sciences. 2014;343(1–2):23–9. doi: 10.1016/j.jns.2014.05.043 24929650

39. Kwon OY, Park SP. Depression and anxiety in people with epilepsy. Journal of clinical neurology. Journal of clinical neurology. 2014;10(3):175–88. doi: 10.3988/jcn.2014.10.3.175 25045369

40. Hesdorffer DC, Caplan R, Berg AT. Familial clustering of epilepsy and behavioral disorders: evidence for a shared genetic basis. Epilepsia. 2012;53(2):301–7. doi: 10.1111/j.1528-1167.2011.03351.x 22191626

41. Insel BJ, Ottman R, Heiman GA. Mood disorders in familial epilepsy: A test of shared etiology. Epilepsia. 2018;59(2):431–9. doi: 10.1111/epi.13985 29318616

42. Babtain FA. Impact of a family history of epilepsy on the diagnosis of epilepsy in southern Saudi Arabia. Seizure 2013;22:542–7. doi: 10.1016/j.seizure.2013.04.002 23628167

43. Wang J, Mann F, Lloyd-Evans B, Ma R, Johnson S. Associations between loneliness and perceived social support and outcomes of mental health problems: a systematic review. BMC psychiatry. 2018;18(1):156. doi: 10.1186/s12888-018-1736-5 29843662

44. Mama SK, Li Y, Basen-Engquist K, Lee RE, Thompson D, Wetter DW, et al. Psychosocial mechanisms linking the social environment to mental health in African Americans. PloS one. 2016;11(4):e0154035. doi: 10.1371/journal.pone.0154035 27119366

45. Letvak S. The importance of social support for rural mental health. Issues in mental health nursing. 2002;23(3):249–61.

46. Haile K, Awoke T, Ayano G, Tareke M, Abate A, Nega M. Suicide ideation and attempts among people with epilepsy in Addis Ababa, Ethiopia. Annals of general psychiatry. 2018;17(1):4.

47. Yimam K, Kebede Y, Azale T. Prevalence of common mental disorders and associated factors among adults in Kombolcha Town, Northeast Ethiopia. Journal of Depression and Anxiety S. 2014;1:2167–1044.

48. Tsegabrhan H, Negash A, Tesfay K, Abera M. Co-morbidity of depression and epilepsy in Jimma University specialized hospital, Southwest Ethiopia. Neurology India. 2014;62(6):649. doi: 10.4103/0028-3886.149391 25591679

49. Tegegne MT, Mossie TB, Awoke AA, Assaye AM, Gebrie BT, Eshetu DA. Depression and anxiety disorder among epileptic people at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia. BMC Psychiatry 2015;15(210). doi: 10.1186/s12888-015-0589-4 26328614

50. Bifftu BB, Dachew BA, Tiruneh BT, Tebeje NB. Depression among people with epilepsy in Northwest Ethiopia: a cross-sectional institution based study. BMC research notes. 2015;8(1):585.

51. Chandrasekharan SC, Menon V, Wadwekar V, Nair PP. High frequency of depressive symptoms among adults with epilepsy: Results from a Hospital-based study. Journal of neurosciences in rural practice. 2017;8(Suppl 1):S13. doi: 10.4103/jnrp.jnrp_21_17 28936065

52. Henok A, Lamaro T. Knowledge about and attitude towards epilepsy among Menit Community, Southwest Ethiopia. Ethiopian journal of health sciences. 2017;27(1):47–58. doi: 10.4314/ejhs.v27i1.7 28458490

53. Bifftu BB, Dachew BA, Tiruneh BT. Perceived stigma and associated factors among people with epilepsy at Gondar University Hospital, Northwest Ethiopia: a cross-sectional institution based study. African health sciences. 2015;15(4):1211–9. doi: 10.4314/ahs.v15i4.21 26958023

54. Charfi N, Daoud S, Farhat N, Bouali MM, Zouari L, Zouari N, et al. Prevalence of psychiatric comorbidities in epilepsy. European Psychiatry. 2017;41:S470.

55. Kanner AM. Management of psychiatric and neurological comorbidities in epilepsy. Nature Reviews Neurology. 2016;12(2):106. doi: 10.1038/nrneurol.2015.243 26782334

56. Li T. Epilepsy and associated comorbidities. Neuropsychiatry (London). 2017;1(1):1–3.

57. O’Rourke G, O’Brien JJ. Identifying the barriers to antiepileptic drug adherence among adults with epilepsy. Seizure. 2017;45:160–8. doi: 10.1016/j.seizure.2016.12.006 28063375

58. Chaka A, Awoke T, Yohannis Z, Ayano G, Tareke M, Abate A, et al. Determinants of depression among people with epilepsy in Central Ethiopia. Annals of general psychiatry. 2018;17(1):27.

59. Jackson M, Turkington D. Depression and anxiety in epilepsy. Journal of Neurology, Neurosurgery & Psychiatry. 2005;76(suppl 1):i45–i7.

60. Stephen LJ, Wishart A, Brodie MJ. Psychiatric side effects and antiepileptic drugs: observations from prospective audits. Epilepsy & Behavior. 2017;71:73–8.


Článek vyšel v časopise

PLOS One


2020 Číslo 1