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Trends of the prevalence and incidence of hypertrophic cardiomyopathy in Korea: A nationwide population-based cohort study


Autoři: Inki Moon aff001;  Seo-Young Lee aff001;  Hyung-Kwan Kim aff001;  Kyung-Do Han aff002;  Soongu Kwak aff001;  Minkwan Kim aff001;  Hyun-Jung Lee aff001;  In-Chang Hwang aff003;  Heesun Lee aff004;  Jun-Bean Park aff001;  Yeonyee E. Yoon aff003;  Yong-Jin Kim aff001;  Goo-Yeong Cho aff003
Působiště autorů: Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea aff001;  Department of Medical Statistics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea aff002;  Department of Cardiology, Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Gyeonggi, South Korea aff003;  Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea aff004
Vyšlo v časopise: PLoS ONE 15(1)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0227012

Souhrn

Temporal trends of the prevalence and incidence of hypertrophic cardiomyopathy (HCM) have not been well established in Asian populations. Using the Korean National Health Insurance Services database, we identified patients with a confirmed diagnosis of HCM between 2010 and 2016. The annual prevalence and incidence of HCM, and their clinical characteristics were investigated. The prevalence of HCM has increased from 0.016% (n = 6313) in 2010 to 0.031% (n = 13,035) in 2016. During a 7-year period, 13,229 patients were newly diagnosed with HCM. The incidence rate increased from 4.15 (per 100,000 person-years) in 2010 to 5.6 in 2016. The prevalence and incidence of HCM increased with age and peaked during the 70s, with male predominance in all age groups. Chest pain is the most frequent clinical presentation followed by shortness of breath and syncope. Hypertension and dyslipidemia were the two most common comorbidities. Heart failure and atrial fibrillation was diagnosed in about 1/3 and 1/4 of patients with HCM, respectively. The prevalence and incidence of HCM gradually increased from 2010 to 2016, possibly due to heightened recognition of the disease. Given the progressively high incidence of HCM with age and high prevalence of coexisting modifiable risk factors, continued efforts are required to increase awareness regarding HCM-related symptoms and potential complications.

Klíčová slova:

Atrial fibrillation – Cohort studies – Diagnostic medicine – Health insurance – Hypertension – Medical risk factors – Cardiomyopathies


Zdroje

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