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Error metrics determination in functionally approximated circuits using SAT solvers
Authors: Sa’ed Abed aff001; Ali A. M. R. Behiry aff001; Imtiaz Ahmad aff001
Authors place of work: Computer Engineering Department, College of Engineering and Petroleum, Kuwait University, Kuwait, Kuwait aff001
Published in the journal: PLoS ONE 15(1)
Category: Research Article
doi: https://doi.org/10.1371/journal.pone.0227745Summary
Approximate computing is an emerging design paradigm that offers trade-offs between output accuracy and computation efforts by exploiting some applications’ intrinsic error resiliency. Computation of error metrics is of paramount importance in approximate circuits to measure the degree of approximation. Most of the existing techniques for evaluating error metrics apply simulations which may not be effective for evaluation of large complex designs because of an immense increase in simulation runtime and a decrease in accuracy. To address these deficiencies, we present a novel methodology that employs SAT (Boolean satisfiability) solvers for fast and accurate determination of error metrics specifically for the calculation of an average-case error and the maximum error rate in functionally approximated circuits. The proposed approach identifies the set of all errors producing assignments to gauge the quality of approximate circuits for real-life applications. Additionally, the proposed approach provides a test generation method to facilitate design choices, and acts as an important guide to debug the approximate circuits to discover and locate the errors. The effectiveness of the approach is demonstrated by evaluating the error metrics of several benchmark-approximated adders of different sizes. Experimental results on benchmark circuits show that the proposed SAT-based methodology accurately determines the maximum error rate and an average-case error within acceptable CPU execution time in one go, and further provides a log of error-generating input assignments.
Keywords:
Simulation and modeling – Algorithms – Probability distribution – Logic circuits – Electrical faults – Computing methods – Electrical circuits – Monte Carlo method
Introduction
Approximate computing has emerged as a promising architectural concept which offers new opportunities to design circuits or systems which can be more compact, faster and/or consume less power at the cost of a slight loss of accuracy for error-tolerant applications [1]. Error - tolerant applications are the ones where precise computational accuracy is not required which include deep machine learning, image classification, and digital signal processing (DSP) [2]. For example, in DSP applications, human perception is not precise enough to detect a certain range of errors. Therefore, a product of identical (perceived) quality can be presented with lower energy costs or higher performance. Chippa et al. [2] estimated that in certain applications, about 83% of runtime is spent on operations that can be approximated. Different types of approximations have been reported in literature for the design of approximated circuits [1]. The form of approximation addressed in this paper is known as functional approximation; in which the Boolean functions implemented into the circuits are inherently different from the original ones with a certain threshold of error between the outputs of both functions.
The emergence of approximate computing has led to the need for adequate evaluation methods for approximate circuits where besides normal metrics such as area, delay, and power consumption, measurement of error metrics is an important consideration and a key challenge. Error metrics provide a quantifiable measure to judge exactly how far off an approximate design is from the correct one, which is critical for the use of approximate circuits in real-life applications. Some of the error metrics measured by existing approaches include worst-case error, average case error, error rate (error probability), and maximum bit-flip error (maximum Hamming distance) [3]. Worst-case error, as the name implies, is the worst possible deviation in values between the two circuits for a single input assignment, which is relevant, for example, in a DSP application where a worst-case error pixel would stand out. Average-case error is the expected error mean value to be found across all input assignments. This would also be seen in a DSP environment where the overall color grading of an approximated image could be affected by a poor average-case error. Maximum bit-flip error is the number of incorrect bits in the approximated circuit, which is relevant to memory address approximation. Error rate is the percentage of input assignments that produce errors in the approximated design that is an indication of the number of introduced errors in the design by the approximation process.
The error metrics mentioned earlier are independent from one another. A circuit with a high error rate does not imply that there is a high maximum bit-flip error or high worst-case error. The relevancy of an error metric is purely based on the application the design is intended for. However, determination of error metrics in approximate circuits is a hard problem [3]. Current error metric evaluation methods suffer from several problems. Simulation-based approaches have prolonged runtimes, and symbolic BDD [4] representation suffers from the state explosion problem. Finally, analytical methods are intractable for larger designs. SAT solver methods [5] have been reported to determine worst-case error and bit-flip error, but not for the maximum error rate or an average-case error, as will be explained in more detail in the related work section. SAT solvers are tools that can determine if a Boolean function is satisfiable; there is a combination of inputs that produces a logic 1.
In this paper, we propose a novel methodology, using SAT solvers to accurately and efficiently determine the maximum error rate and an average-case error. Recent SAT solvers are quick enough to efficiently check relaxed equivalence in many practical situations. We focus on the maximum error rate and an average-case error since these are the hardest to compute, requiring enumeration of all errors and calculation of their values. However, the proposed approach is applicable and can measure all relevant error metrics, since we generate all inputs that produce errors (and their corresponding output values), and then can calculate any of the error metrics. An overview of the proposed methodology is depicted in Fig 1, in which first the approximated and exact designs are combined using an auxiliary circuit called the approximation miter. The approximation miter transforms both designs into one design with a single output and the same inputs. The output of the miter is 0 when the two designs match and are correct. The output of the miter is 1 when the approximated circuit’s output has an erred bit. This new circuit is fed into the SAT solver to determine the error metrics. The proposed evaluation methodology is important since it provides a relatively fast and reliable way for designers to evaluate their approximate circuit designs. The effectiveness of the approach is demonstrated by evaluating the error metrics of several benchmark-approximated adders of different sizes.
Fig. 1. Overview of the proposed methodology. The main contributions of this paper can be summarized as follows:
We propose a SAT-Solver-based algorithm for all error metrics (particularly the maximum error rate and an average-case error) in approximated circuits, given an original circuit.
The method takes advantage of the computational miter to combine the two circuits and eventually transform the circuit into a CNF format, while saving the original variable mapping to the inputs.
The algorithm can calculate all error metrics and identify the input configurations that produced them in a single run.
We prove the correctness of our approach by testing the algorithm on commonly used approximate adders and comparing them with the exact adders.
The remainder of this paper is organized as follows. Various error metrics determination methods applicable to approximate circuits are presented in Section 2. Section 3 provides an overview of the terminology and key concepts used in this work, and describes the error metrics and the main functionality of a SAT solver. The problem statement and proposed solution methodology are discussed in Section 4. A proof of method correctness and an evaluation of the proposed methodology supported by experimental results is described in Section 5. Finally, conclusions and future research opportunities are presented in Section 6.
Related work
Error metrics are essential tools for of evaluation digital circuits. This is particularly true in the case of approximate circuits, where it is a tool for measuring the adequate correctness of a design that is made to not be precisely exact. The degree of acceptance of approximate designs is usually subjected to many error metrics, such as error rate, maximum bit-flip error, worst-case error, or average-case error.
Typically, even though worst-case errors can be computed for a specific component, on its own, the accumulated worst-case error may differ significantly. Therefore, individual analysis of isolated components is not sufficient for evaluation of approximate circuits. It requires a different set of tools to evaluate the error metrics of larger circuits. Furthermore, different error metrics have varying significance depending on the circuit’s application. Although error-rate may not be a significant metric in some applications, where the error significance/worst-case error may matter more (the value of a pixel), there are several other applications where error-rate is an important metric (e.g. the number of incorrect memory address computations in a microprocessor) [6]. Apart from the application-specific significance of error rate, it is a general quality metric for approximate designs. Error-rate multiplied with error-significance is used as a composite quality metric for approximate circuit designs [7].
There have been many designs and synthesis methods for approximate computing circuits, but not many on precise error metrics [5]. Several approaches determine these metrics, including simulation, analytical analysis, Boolean Satisfiability (SAT solvers), and BDDs. Methods of formal design verifications to evaluate error metrics have been used and implemented, such as Bounded Model Checking (BMC). Currently, the techniques used most often to evaluate the approximate designs are random simulation and error estimation, which are inexact approaches [8, 9]. When BMC is applied to sequential equivalence checking, the circuit is unrolled and the overall problem including the properties is solved using a SAT solver [5]. Some error metrics such as error-rate cannot be expressed in terms of Boolean functions efficiently since it requires counting in the solution space, which is a SAT problem [10].
The authors of [5] proposed a methodology and tool to determine precisely how error behaves in approximated combinational components in sequential circuits. They implemented the use of an approximation miter and preformed model checking using Property-Directed Reachability (PDR). They calculated several error metrics and tried to answer multiple verification questions. In addition, they attempted to determine the earliest time (in clock cycles) that can exceed a certain worst-case error, the maximum case error, and the maximum bit-flip error. They tested their verification package on a number of approximate designs and reported the results. However, they did not calculate metrics for error rate or average-case error.
Yu et al. [8] presented a case study to analyze the output quality of imprecise adders for their use in approximate computing. The authors adopted a formal verification of approximate adders based on BDDs rather than random simulation or error estimation in order to retrieve exact error analysis. In order to adapt their methods to the BDD, XOR gates were used to check the equivalence of the outputs followed by a “miter” (a word-wide OR gate). The proposed framework could compute the exact error rates of the designs studied. The methods provided were able to generate test patterns that cover all possible errors produced by the imprecise adders. The work of the authors remained to be tested on larger circuits, such as multiplication. This is an important point, as BDDs suffer from state explosion problems. In [9], Anteneh et al. presented an automatic test pattern generation approach for approximate circuits based on Boolean satisfiability. The technique reduced the number of faults and the testing time, while maintain high fault coverage.
Chandrasekharan et al. [10] proposed an automatic synthesis methodology for approximating circuits using And-Inverter Graph (AIG) rewriting. The synthesis approach employed bounds on the approximation errors introduced in the design. The methodology was tested on a variety of designs and benchmarks. The authors claimed that their results were comparable with hand-crafted approximate circuits. Their evaluation of error-rate involved using BDDs. The exact approach used was unique to BDD-based representation. This led to extended run-times caused by the need for conversion from AIG to BDD. They also presented an algorithm to calculate bit-flip error using a SAT solver.
Choudhury et al. [11] proposed a concurrent error masking methodology based on the use of approximate logic circuits. The approach was estimated to mask 88% of targeted errors for a 34% area overhead and 17% power overhead because of the use of approximate circuits. They evaluated error metrics for their approach via simulation of the approximate logic circuit designs and employed the use of reliability analysis tools.
Jiang et al. [12] presented a comparative study between approximate multipliers. The authors provided a review of the different implementations of approximate multipliers’ current designs and compared their evaluations. The authors also used Monte Carlo simulation using MATLAB for error metric determination in their comparison of approximate multipliers. Furthermore, they evaluated the multipliers based on their performance in image sharpening in the MATLAB environment.
Momeni et al. [13] proposed designs of approximate compressors to be used in multiplication. Approximate adders were not viable to produce multiplication because of the error accumulation. Previous work had been done on multipliers, but the paper is unique in its use of compressors for multiplication. Two approximate compressors and four approximate multipliers were simulated using HSPICE.
Huang et al. [14] provided an overview of imprecise hardware, improved upon imprecise adders, and proposed imprecise multipliers. They stated that numerical analytical analysis was a superior method of error metric computation, when compared to simulation. Their methodology followed two constraints: the only allowed operations were addition and multiplication, and input data were independent of one another. The approach used Interval Arithmetic and Affine Arithmetic for error evaluation. They concluded that their methodology provided higher speed computation with reasonable estimation close to exhaustive search with runtime being orders of magnitude less than Monte Carlo simulation.
Most of the past works used simulation as a means of estimating the error metrics, however, there have been combined methodology that used simulation and other means to maintain accuracy of evaluation and avoid exponentially increasing runtime. Venkatesan et al. [15] proposed a methodology for Modeling and Analysis of Circuits for Approximate Computing (MACACO). MACACO used several methods for its formal verification. Worst-case error was computed using a pseudo-SAT solver approach. The authors also computed error probability and average-case error by two means, a BDD package and Monte Carlo-based simulation. The Monte Carlo simulation method was used to assume scalability, as BDD based computation was not deemed feasible for all circuits according to the authors.
Similarly, Soeken et al. [16] used BDD-based methods to compute error metrics. This was to their benefit, as their methodology for synthesizing approximate circuit designs was also based on BDD minimization of Boolean functions. Therefore, some of the error metrics (error rate) were calculated during the minimization process. It was stated that because the methodology was based on BDDs, the error metric evaluation was not applicable on much larger circuits in their current implementation. The authors suggested changing the underlying data structure to AIGs; however, it was not clear if error metrics can be computed efficiently.
Recently, Froehlich et al. [17] proposed a formal three-stage approach for the determination of all error-metrics for an approximate circuit. The determination of several error-metrics was facilitated by the main bulk of the work being done by a Gröbner reduction and an Algebraic Decision Diagram (ADD) that did not need to be repeated for different error metrics. They used a recursive and hash function to determine the minterms.
Other means of error metric estimation include probabilistic analysis. Mazahir et al. [18] proposed a generic methodology for calculating the exact probability of occurrence of any errors in approximate adders and the probability mass function (PMF) of errors for any input distribution without the need of exhaustive or Monte-Carlo simulation. The methodology was based on the internal structures of adders and the probability of carry-in/carry-out. It is worth noting that the proposed approach is specific to approximate adders only, and is applicable when a combination of approximate adders is used. Later, Qureshi et al. [19] used HOL4 interactive theorem, proving for probability distribution and error analysis of three high-speed, low-latency approximate adders with uniformly distributed inputs. Mazahir et al. [20] provided a probabilistic analysis of errors in an approximate multipliers construct from given blocks. The methodology was based on the internal probabilistic behavior of the building blocks cascading to create larger multipliers. The analysis of [20] was generalized for any input probability distribution and the probability mass function of error was found. The experimental results applied the methodology on state-of-the-art multipliers to compute their probability mass functions and predicted their performance in an image-processing application. The authors of [21] proposed a probabilistic analysis methodology for analyzing two-part segmented adders and derived the mean error distance and mean square error in the approximate adders.
Similarly, Wu et al. [22] adopted an analytical methodology with assumptions on the inputs to the approximate circuits. They assumed that inputs were uniformly distributed to adders and thus proposed a method based on the building blocks of approximate adders. The method was also shown to be able to compute the probability mass function of errors (error distribution). It was experimentally shown that the procedure was less computationally extensive than Monte Carlo simulation. It is worth noting that the methods reviewed in [20] and [22] are precise and are suitable only for block-based multipliers and adders, respectively. Furthermore, depending on the application and context a hardware component is used in, it might not necessarily be possible to assume a probability distribution for input assignments.
A popular approach to evaluate approximate circuits in the literature is to employ the approximated circuit on an application it would normally be used for and evaluate its performance. This is a popular method because of its simplicity, but the work risks being applicable only to the tested application. Examples of such works [23, 24] have utilized approximate multipliers and adders in image processing scenarios. The error metric then is measured on the test data (input images) and how well the approximate circuits formed the image as opposed to the ideal situation.
Another important implication of approximate circuit fabrication is the acceptance of faulty units that fall within the appropriate range of error metrics required. The authors of [25] presented an approximation-aware test approach to identify approximate-redundant faults. The proposed approach guaranteed that the faults had effects that fall below the acceptable thresholds using a SAT solver and miter approach, and specific automatic test generation patterns.
It can be noted that the most prominent form of error metric evaluation has been the Monte Carlo simulation. This might be a feasible way of determining error metrics for smaller designs. The major issue with the simulation approach is the simulation time that grows exponentially with data width and computation length [14] for evaluating larger approximate designs. The same issue lies with the analytical approaches as they become harder and more complicated to deploy with increased design complexity, particularly if accuracy is considered. The BDD approach can produce exact determinations of error metrics as reported in the works above. In fact, in some approaches this is favorable, since the synthesis procedure requires BDD representation in the first place, and therefore, error metrics can be computed during minimization [16]. Some of the error metrics, such as the error rate, are SAT problems, since they require counting in the solution space [10]. However, SAT approaches to BMC are more scalable than their BDD counterparts [26]. Therefore, the goal of this paper is to implement a SAT solver-based scalable approach in order to enable exact error metrics calculation. The two-error metrics that have been previously implemented using SAT solvers are the worst-case error [15] and bit-flip error [10]. These are simpler metrics to calculate using SAT solvers as they involve searching for a single input assignment in the solution space that leads to maximum value. This paper aims to add to those approaches by introducing an approach for calculating the maximum error rate and an average-case error determination via SAT solving on a CNF representation of an approximated design.
Preliminaries and background
This section will define glosses over important terminology and key concepts required in this work. The error metrics subsection describes all error metrics, followed by the SAT solver subsection, which describes the main functionality of a SAT solver and recent advancements in the use and applications of SAT solvers. Finally, the miter subsection explains the importance of an auxiliary circuit and how it is used to manipulate designs in order to feed them into a SAT solver and extract a result/metric.
Error metrics
Approximate circuit designs need to be evaluated to determine their usefulness. One of the important evaluations is how much does the approximated design deviate from the exact one. In the class of functionally-approximated circuits, the approximated circuits are typically compared to the original exact designs to determine the disparity between the two designs. Error rate is a challenging metric to calculate, as it includes checking the probability of error bits overall in the design. Let f be a Boolean function that represents the exact design such that f: Bn→Bm and another Boolean function f^:Bn→Bm represents the approximate circuit. Using this notation, the worst-case error is defined as:
Eq (1) represents the maximum possible difference between the outputs of the two designs, given that we represent the output of both circuits as integer values [9].
Similarly, bit-flip error can be defined as:
Eq (2) denotes bit-flip error, or the maximum number of bits that differ in both outputs.
The error metrics mentioned above have been previously calculated using SAT solver approaches. As noted from Eqs (1) and (2), these error metrics focus on finding a maximum value, which is a single point in the solution space. This makes the problem far more approachable as a binary search technique can be employed along with a specifically designed auxiliary circuit to calculate both metrics. Binary search reduces the computational complexity of the problem.
Error-rate and average-case error are more computationally intensive as they require iteration over all solutions/errors possible. Error rate can be stated as:
This can be read as the fraction of inputs that produce a different output pattern in the approximated circuit other than the exact one [10]. This requires a count of the number of errors between the two circuits (the numerator in Eq (3)) which is also known as the #SAT problem.
Finally, the average-case error can be expressed by:
Eq (4) can be explained as the summation of the absolute difference of outputs of the two circuits produced by every input assignment divided by the number of possible input assignments. Obviously, for the input assignments that do not produce errors, the value inside the summation is zero. Therefore, we need only to perform the summation for values of x that produce errors.
SAT solver
The SAT problem considers a Boolean expression and checks if there is an input assignment(s) that result in the Boolean expression returning a true value. This Boolean expression is input into the SAT solver in the form of a combination of logical clauses. Modern SAT solvers are capable of quickly traversing BDDs and solving millions of propositional clauses in acceptable time frame [5].
SAT solvers have picked up steam as a promising tool to approach many research problems. The applicability of SAT solvers does not just lie in the Boolean network plane. The work of [27] used a SAT-based formulation for calculating the logical-capacity of VIA-configurable structures ASIC (VCSA) fabric. The model used the physical properties of a problem and formulated them into Boolean terms and clauses to be processed by the SAT solver. Another project [28], used a SAT solver to determine short-circuit conditions in logical circuits. Short-circuits in a logic circuit can be induced by several causes such as: a designer connecting two outputs of a module, assuming certain unreliable assumptions. The authors modeled the transistors in the circuit as a graph and tried ensuring that there was no way the power source was connected to the ground via any path. They transformed this problem into a series of Boolean clauses that were then checked by the SAT solver.
There are multiple variations of SAT solving methods (all with the same goal). The details of implementation of such solvers is deemed outside the scope of this paper. However, for the concerned interested reader, information on the SAT solvers relevant to this work is available in [29]. The SAT solver used for this project is a backtracking-based non-blocking SAT solver. Meaning the SAT solver searches for the counter-examples one by one with backtracking without storing the counter examples back into the original problem. This specific strategy was chosen simply because it proved to be the best in practice and used the least amount of memory.
SAT solvers accept a specific format of several Boolean clauses. Therefore, one must change the problem at hand of equivalence checking two circuits (and hence average-case error/error-rate calculation) into a SAT problem. This requires us to first combine both circuits into one in order to feed it into the SAT solver.
Auxiliary circuits
In order to take advantage of the SAT solver to check equivalence between the two circuits, one must first transform the circuit into a form the SAT solver can use. SAT solvers operate on a number of clauses to determine if they can all be satisfied. Digital circuits can have any number of outputs. Therefore, an auxiliary circuit is built around the exact and approximated designs in order to convert it into a single output and evaluate the desired error metric. Assuming the exact circuit is the black box F and the approximated circuit is the black box G, then the auxiliary circuit can be seen in Fig 2. The general block diagram shows the structure of the auxiliary circuit such that both circuits G and F have the same inputs and both of their outputs lead to the error block, which is the error determination block that produces the error value e or assists in finding e. The structure of the error determination block differs based on the type of error metric to be determined. The error determination block can simply check if all the outputs from both circuits are equivalent, or it can contain comparators or arithmetic operations to evaluate specific error metric.
Fig. 2. Block diagram of auxiliary circuit. Proposed methodology
The following subsections present our proposed solutions to the problem of error metrics determination in approximate circuits. The proposed solution consists of three main stages as shown in Fig 3.
Fig. 3. Detailed proposed methodology. Yosys [30] receives the approximate and exact designs, combines them and produces the design as a BLIF (through Yosys). Then, a script processes the BLIF file into a CNF file to enable it to be fed to the SAT solver, and finally, runs the modified ALLSAT solver to determine error metrics for the resulting combined design. Yosys is used to apply the combinational miter, as well as to synthesize the circuit into simple gates/cells. The script is designed to print out a variable mapping that preserves the CNF IDs of the variables of interest that are the inputs and outputs of both circuits. This information is essential to the modified SAT solver to be able to extract the differences between the two circuits and calculate average-case error. The algorithm depends on the fact that both error rate and average-case error require complete coverage of all the errors in the solution space to determine the exact error metric value. Therefore, the SAT solver approach is used to search through the solution space and generate all the error-producing assignments. The number of these assignments can be used to calculate the error rate metric using Eq (2). The input assignments generated can then be simulated for both circuits and used with Eq (4) to calculate average-case error. This form of simulation is cheaper as the run time does not scale with the number of inputs to the circuits. The runtime scales only with the number of unique errors in the circuit. Although the worst possible situation for this approach would be if the number of errors is 2n (i.e. every input assignment leads to an error). This is highly unlikely as the circuit usually has a great deal fewer errors than that and synthesis approaches provide an upper limit on number of introduced errors. The modified SAT solver can list the inputs and outputs of the two circuits when errors occur between them. However, listing of the output differences is optional and is not needed for any calculations, but is left as an option for interested designers.
Auxiliary circuits
The following subsections show examples of the auxiliary circuitry needed to evaluate the maximum error rate and an average-case error. The error rate auxiliary circuit is simply an approximation miter that compares, bit by bit, each of the outputs of the two circuits. In case of the average-case error, some form of accumulator would need to be built around the absolute difference of the two circuits. This is just for clarification and the actual implementation uses an approximation miter for both circuits.
Maximum error rate
In the case of error rate, the error determination block is an approximation miter, which is basically ORing the equivalence of each output of both circuits. To illustrate this design concept, we assume a simple design where F and G have three outputs; the structure of the error rate would look like Fig 2. Each output in the circuits F and G are XORed to determine their equivalence. As shown in Fig 2, the outputs (f0,g0), (f1,g1) and (f2,g2) are XORed. Hence, any of these XORed outputs will return a logic 1 wherever their outputs are not equivalent. Therefore, the overall output of the approximation miter will be 1 whenever the output of the approximated circuit G does not match the output of the exact circuit F. The error rate can then be computed as expressed in Eq (3).
Eq (3) represents the global OR of the XORs of each output in both systems (where m is the number of outputs). The number of such inputs that produce a 1 value in the miter are added up and divided by 2n to determine the error rate of the approximated system (where n is the number of inputs). Therefore, the addition of the auxiliary circuit turns the two designs into one design with the same number of inputs n and one output e, where e can only be 1 when the two sub-designs are not equivalent [16].
Average-case error
Average-case error metric resembles error rate in that it is not concerned with a single output value. Average-case error includes all the possible errors generated by the approximated design. The circuit to calculate the error can be visualized as a combination of the circuits in Figs 2 and 4. The circuit in Fig 2 is used to detect the existence of an error. The circuit in Fig 4 is then used to calculate the value of that error and accumulate it across all input assignments. Therefore, practically the implemented solution is running the SAT solver on the circuit in Fig 2 to enumerate the input assignments that produce errors. Those input assignments are used to create a test bench for the circuit. The average-case error can then be calculated by using Eq (4).
Fig. 4. Total error approximation miter example. It is important to note is that not all n input variables must appear in a solution. The variables that do not appear in a path can be considered do-not cares, as they do not affect the output of the miter. One of the advantages of this process is that it does not need to include every variable and therefore the use of do-not cares can list several input assignments at once and hence the numeration of errors can be summarized. The number of input assignments represented by a path is equal to 2c input assignments where c is the number of do-not cares.
SAT solving
Maximum error rate
Error rate involves counting the number of solutions which satisfy the SAT problem. This can be denoted as the ALLSAT problem, which is searching through the solution space for all input assignments that satisfy a circuit. It can be noted that the #SAT problem, which is counting the number of satisfying input assignments, is enough to solve the maximum error rate metric alone. However, in order to aid the algorithm in calculating the average-case error and error rate in one step, we propose the ALLSAT solution. The ALLSAT is an incremental running of the SAT solver in order to collect all counter examples that lead to satisfying the miter. Note that ALLSAT solver stores implications from past iterations in order to speed up future iterations. This gives the algorithm another advantage that enumerates the input assignments that lead to errors, which can be very useful for debugging purposes. We propose an algorithm that combines all the details mentioned to determine the maximum error rate and average case error as shown in Algorithm 1. Furthermore, using the ALLSAT solution for both error-metrics allows us to only use one auxiliary circuit (Fig 2) instead of having to apply both for the two different metrics.
Algorithm 1: Error Metric Computation Algorithm
Input: Verilog Circuit F, Verilog Circuit G
Output: Maximum Error Rate MER, Average-case Error AVG, Set of counterexamples L
1: M = ApplyMiter (F, G)
2: MBLIF = WriteBlif (M)
3: [CNF, MAP] = BLIF2CNF (MBLIF)
4: [MER, AVG, L] = MOD_ALLSAT (CNF, MAP)
Algorithm 1. General Algorithm of Proposed Methodology
The algorithm that takes both the exact and approximate designs, denoted as Verilog Circuits F and G, respectively, as indicated in Algorithm 1. The algorithm returns the maximum error rate and average-case error as a result at the function’s termination and has the option to return the set of error-producing input assignments L. Line 1 shows a Boolean network constructed from F and G by combining them in miter M and adding the auxiliary circuit shown in Fig 2 using Yosys. The newly-developed Boolean Network M is then written in BLIF format as shown by Line 2. The algorithm calls a script BLIF2CNF in Line 3 to convert this combined BLIF circuit into CNF format to be fed into the modified SAT solver in Line 4. The script turns all variable names into index numbers, and therefore a separate map file of all-important variable indexes is printed. This map file contains the variable indexes for the shared inputs of both combined circuits and the individual outputs of both the exact and approximate circuits. This is useful because the output corresponding to an input can be extracted directly from the counterexample provided by the SAT solver as shown in Algorithm 2. The modified SAT solver MOD-ALLSAT then uses the CNF file and the variable map in order to calculate maximum error rate (MER), average-case error (AVG), and optionally the list of error - producing input assignments (counterexamples) denoted as L.
Algorithm 2: Modified ALLSAT Algorithm (MOD-ALLSAT)
Input: CNF File CNF, Variable I/O Map MAP
Output: Maximum Error Rate MER, Average-case Error AVG, Set of counterexamples L
1: AVG = 0
2: ER = 0
3: While CNF is satisfiable do
4: CEX = SAT (CNF) {CEX is a total variable assignment}
5: [input, output1, output2] = ExtractRelevantVariables (CEX, MAP)
6: Add input to L
7: AVG = AVG + | int(output1)–int (output2) |
8: ER ++
9: Update Stored SAT Solving Implications
10: end while
11: MER = ER/2n
12: AVG = AVG/2n
Algorithm 2. Modified ALLSAT Solver Algorithm
A more detailed view of the modified ALLSAT solver (MOD-ALLSAT) used in Algorithm 1 can be seen in Algorithm 2. The MOD-ALLSAT algorithm takes a CNF file and a variable map as inputs and calculates error-rate (ER), average-case error (AVG), and optionally produces the list of counterexamples L. The variables ER and AVG are initialized to zero at the beginning of the algorithm. The ALLSAT solver begins to iteratively find errors in the CNF file. The SAT solver knows that there are no more remaining errors and it can terminate the search, when the problem is no longer satisfiable (Line 3). The SAT solver then works on the CNF file until a satisfying solution (counterexample) is found (Line 4). This solution is presented as a total variable assignment CEX to all inputs, outputs and intermediate variables. It is therefore obvious to state that the value of the single output of the miter will be logic 1 for any satisfying variable assignment. However, for our intended purposes, many intermediate variables are not needed, and in fact, we only care about the original inputs and outputs of both circuits. As seen in Line 5, the assignments the SAT solver found to these relevant variables are extracted from the counterexample. The assigned input is added to the list of error-producing input assignments (Line 6). The two outputs corresponding to the outputs of the original exact and approximate circuits are also extracted. We consider the absolute difference between the integer representation of each value output1 and output2 and accumulate it in the variable AVG (Line 7). In Line 8, the variable ER is incremented to count error-producing input assignments. The SAT solver then updates its internal information before reiterating the entire process until termination (Line 9). This information may include storing intermediate variable implications it learned to avoid redundant processing, as well as taking note of the input assignment it found in the past loop iteration. This is done in order to eventually eliminate all error-producing input assignments and thus making the problem not satisfiable.
A clarifying analogy to this would be deleting the path that has led to the 1 node in the BDD representation so it cannot be followed again. The SAT solver does this iteratively until eventually the equation cannot be satisfied anymore. This means all errors have been detected. The ALLSAT solver is also special in that it does not start from scratch on every iteration (it learns from previous iterations).
After terminating the search, the variable ER now contains the numerator of Eq (3) for maximum error rate calculation. The variable AVG also contains the numerator of Eq (4). The error-rate and average-case error can then be computed by dividing both these variables by 2n, where n is the number of inputs (Lines 11–12). Then the algorithm finishes execution and outputs the error-rate in variable ER, average-case error in variable AVG, and optionally the list of error-producing inputs L. It is worth nothing that both errors are calculated in one go of the SAT solver and with the same auxiliary circuit (the approximation miter).
Methodology correctness–an illustrative example
In order to prove the correctness of the designed methodology, a naïve example was developed for testing. A simple exact ripple carry 4-bit adder and an “approximated” 4-bit adder were written in Verilog. The “approximated” adder was a normal ripple carry adder that added one to every value it calculated to artificially introduce errors. For example, in the approximated adder: 1+1 = 3, 2+2 = 5, etc.
Following the steps of Algorithm 1, the inputs to the algorithm are two circuits: an exact one F (the ripple carry 4-bit adder), and the approximated circuit (adder that increments valid result by one) G. The two circuits are 4-bit adders; therefore, they have 5 outputs each. Yosys is used to apply a miter that XORs each of the 5 outputs to the corresponding output in the other circuit and ORs the result of all the XORs (Line 1). The resulting circuit is produced from Yosys to be converted into a CNF file (Line 2) so it can be fed to the ALLSAT solver. The ALLSAT solver runs on this representation of the miter combining the two circuits (Line 3) and begins to extract all the errors (differences) between them.
Now, since the approximate adder was made to increment one to the result of the exact adder, this means that all input statements produced errors. Hence, the error-rate is 100% (Line 4) and the number of errors (the cardinality of set L) is 256 (8 inputs to the miter circuit, 4 per adder). Lastly, the average-case error is calculated by adding each of the differences generated by all input assignments and dividing by the number of possible assignments. Since the approximate circuit simply outputs the result of the exact adder plus one, then the difference in all errors is one. Therefore, the total accumulated difference is 256 (256 errors of value, 1 each), calculated in Line 7 of the algorithm. The average error rate is then 256/256 (Line 9) such as in Eq 4, equaling 1. All numbers mentioned in this example were achieved practically using the proposed methodology and reported by the SAT solver.
Experimental results
The methodology was implemented using a combination of tools on the library of approximate adders [31]. The Yosys package was used to read two separate Verilog circuit designs (one for the exact and one for the approximated circuit). The Yosys package, with the help from the ABC [32] verification package, was then used to apply the miter circuit, such as the one shown in Fig 2. This design was then synthesized and written into BLIF format. The BLIF format was converted to CNF format (which is a combination of logic clauses) in order to be fed into the SAT solver. This led to a numbering of all variables, which then lose their name when converted to the CNF file. The mapping between the variable names is saved in a map for future processing. The SAT solver used was a modified ALLSAT non-blocking clause solution based on MiniSAT [27]. The solver prints out all input assignments leading to errors and can print out individual error values as well. The solver accumulates all the errors and calculates the average error value. All experiments were carried out on a machine running Linux with an Intel ® core i7 CPU @ 2.9 GHz and 16 GB of memory. Implementation of the described methodology can be obtained at: https://github.com/AliRady/error-metrics-determination/
Experimental results on benchmark adders
Tables 1 and 2 contain the results of running the proposed methodology on a library of 8-bit and 16-bit approximate adders (which have 16 and 32 effective inputs, respectively). The first column denotes the name of the circuit. The size of the approximated adders in basic cells/gates is reported in the second column. In addition, the size of the merged circuit when applying the miter to the approximate adder and the exact ripple carry adder is reported in the Gates in Miter in the third column. Yosys reported all sizes after synthesizing the circuits into basic logic cells. The total number of errors shown in column 4 is the cardinality of the counter-example set found by the ALLSAT solver, which is then used to calculate maximum error rate using Eq (3). The summation of errors in column 5 is the total sum of the absolute difference between the two circuits over all input assignments, used in average-case error calculation. The tables then contain the results of the two metrics: maximum error rate and average-case error in columns 6 and 7, respectively. The last column represents the processing time over the BLIF file containing the two circuits to be compared. The CPU time with numeration shows the required time to run our methodology including the generation of the file listing the inputs that generates the errors.
Tab. 1. Evaluation of 8-bit approximate adder library. Tab. 2. Evaluation of 16-bit approximate adder library. Maximum error rate quantifies the probability that given any two input statements, the outputs of the two adders would be different. The average-case error is a mean value of how large the error would be. For example, there is an 18.75% chance to get an inaccurate output when using the ACA_II_N8_Q4 approximate adder. The expected value of this error (the difference between the two outputs) is 7.5. The main bulk of the CPU time is spent on the SAT solving phase of the methodology, as the application of the miter has negligible processing time. As expected, the CPU time jumps significantly between the 8-bit adders and the 16-bit adders, because the search space grows exponentially with more inputs, making it more compute-intensive to find errors.
The error rate numbers for all the approximate adders exactly matched the ones mentioned in [16], validating that they are correct. The paper did not report an average-case error and therefore the validity of the average-case error results is based on the tests performed with pre-determined results. All numbers reported are exact, therefore achieving them is complex, which is reflected in the runtimes. It is not a challenging task to provide limitations on the metrics, such as terminating the program when a certain error-rate or a certain average-case error is exceeded. Moreover, the authors in [17] did not claim their work to be 100% accurate to the actual error metrics (as they did not provide the values for the errors). In addition, they did not provide all the input combinations that produced errors and they only calculated the metrics. Furthermore, they computed the time for each stage and then calculated each error metric individually. However, our work provides all the input configurations that produce the errors and calculates all error metrics in one run.
From the results, several approximate adders have the same error-rate but different average-case error, such as the ACA_II_N8_Q4 and the GDA_St_N8_M4_P2. The error metrics can therefore be used to categorize circuits into more than one category. Even if the two approximate adders are equally likely to produce an error, the one with a higher average-case error will produce errors that (on average) deviate more from the exact value. This information gives insight to the designer who may value errors that are more impactful over area or power improvements, or vice versa. It is also not impossible for two structurally different adders to have the same value for both metrics, leaving the design choices up to other error metrics or area/power considerations.
To discuss the effect of different design parameters on the runtime of the methodology, the CPU time is reported. Firstly, the effect of the miter size in gates/cells on the runtime is explored in Fig 5.
Fig. 5. Plots of number of gates in miter vs. CPU time for 8-bit and 16-bit adders. The first noticeable difference between the two graphs is the jump in CPU time between the 8-bit adders and the 16-bit adders. This is due to the search space doubling with every introduced input variable, leading to an exponential growth. The other noticeable fact is that there is no pattern to the scatter graphs and hence a more influential variable affecting the CPU time. This factor can be demonstrated by looking at Figs 6 and 7. The CPU time is directly proportional to the maximum error rate and an average-case error in the circuit. As the error-rate or average-case error increases, the CPU time increases linearly for both the 8-bit and the 16-bit benchmark sets.
Fig. 6. Plots of maximum error rate vs. CPU time for 8-bit and 16-bit adders. Fig. 7. Plots of average-case error vs. CPU time for 8-bit and 16-bit adders. The CPU time scales with the maximum error rate because the higher the maximum error rate the more the number of errors that need to be discovered, therefore more work.
The average-case error metric has more to do with the severity of the error, i.e., the average absolute difference between the two circuits in value when considering both their outputs as integers. For example, two approximate circuits might both have one error. But one of them has the error in the most significant bit and the other in the least significant bit. Therefore, they both end up taking the same CPU time to process but different average-case error.
Finally, this effect is consistent even if both benchmarks sets are considered together. However, in order to plot both benchmarks sets together, we need to consider the number of existing errors (Total Number of Errors in Tables 1 and 2) as the size of the search spaces are different. The resulting plot indeed produces a linear relation as shown in Fig 8.
Fig. 8. Plots of number of errors vs. CPU time for all benchmarks. The proposed SAT solving methodology was shown to be applicable to the new error metrics studied by deriving correct error metric results to the benchmark circuits. The approach provided a quantifiable measurement of the two error metrics in one step to exactly determine the difference between the approximate and the correct design. This is done by providing the set of all error-producing assignments and the errors produced by them to determine the practicality of approximate circuits.
Conclusion and future works
Approximate computing has gained enormous research attention recently by providing a trade-off between computational accuracy and computation effort for the emerging inherent error-tolerant applications. However, to reap the promising benefits of approximate computing, fast and accurate error metrics evaluation methodology is of paramount importance. Error metrics are a crucial factor in the usefulness of approximate circuits in real-life applications. The relevant importance of an error metric is application dependent, and hence, there should be efficient procedures to accurately determine all error metrics. In this paper, two key error metrics were considered that have not been addressed before using a SAT solver methodology. However, the approach is applicable to evaluate all relevant error metrics. In our opinion, this may be the first work to propose SAT solver method for the evaluation of all relevant error metrics in approximate computing. Experimental results using several benchmark approximate adders with varying sizes showed the feasibility of the proposed SAT based methodology. There are some key advantages to the approach, as it provides the set of all error-producing assignments and optionally the errors produced by them. Moreover, it offers a test generation method to facilitate design choices and acts as an important guide to debug the approximate circuits (perhaps there is an error where it should not be). The proposed work was effective in processing the two error metrics in one go, and provided a log of error-generating input assignments in a reasonable timeframe. It was shown experimentally that the processing time of the methodology increases, as expected, rapidly with a few inputs but only linearly with the number of errors it needs to detect.
However, several challenges remain that open interesting research opportunities for future work to realize the full potential of the emergent approximate computing paradigm. It includes the study of the correlation of metrics with each other and with approximation techniques, as well as the evaluation of combined error-metrics and their impact (e.g. Hamming distance) on different applications. Another important extension of this work will be experimenting with the internal algorithm of the SAT solver and discovering if different algorithms might behave better with some circuits and worse with others. The development of parallelized ALLSAT solvers is likely to be a valuable addition in terms of speed of processing.
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- Multiregional origins of the domesticated tetraploid wheats
- Racism against Totonaco women in Veracruz: Intercultural competences for health professionals are necessary
- Increased inflammation and endothelial markers in patients with late severe post-thrombotic syndrome
- Genes associated with body weight gain and feed intake identified by meta-analysis of the mesenteric fat from crossbred beef steers
- Intraoperative computed tomography imaging for dose calculation in intraoperative electron radiation therapy: Initial clinical observations
- Multiple paedomorphic lineages of soft-substrate burrowing invertebrates: parallels in the origin of Xenocratena and Xenoturbella
- Human lung epithelial BEAS-2B cells exhibit characteristics of mesenchymal stem cells
- Simple non-mydriatic retinal photography is feasible and demonstrates retinal microvascular dilation in Chronic Obstructive Pulmonary Disease (COPD)
- Evaluating poverty alleviation strategies in a developing country
- RNAmountAlign: Efficient software for local, global, semiglobal pairwise and multiple RNA sequence/structure alignment
- Maternal depressive symptoms and children’s cognitive development: Does early childcare and child’s sex matter?
- Pan-cancer analysis of somatic mutations and epigenetic alterations in insulated neighbourhood boundaries
- Evaluation of a bioengineered ACL matrix’s osteointegration with BMP-2 supplementation
- Psychosocial profiles of physical activity fluctuation in office employees: A latent profile analysis
- Prevalence and characteristics of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) isolated from chicken meat in the province of Quebec, Canada
- HIV treatment response among female sex workers participating in a treatment as prevention demonstration project in Cotonou, Benin
- Soluble AXL as a marker of disease progression and survival in melanoma
- Using machine learning methods to determine a typology of patients with HIV-HCV infection to be treated with antivirals
- Quantifying tourism booms and the increasing footprint in the Arctic with social media data
- Gender differences influence over insomnia in Korean population: A cross-sectional study
- Impact of scion/rootstock reciprocal effects on metabolomics of fruit juice and phloem sap in grafted Citrus reticulata
- Adapting cognitive diagnosis computerized adaptive testing item selection rules to traditional item response theory
- Usability assessment of seven HIV self-test devices conducted with lay-users in Johannesburg, South Africa
- Autumn shifts in cold tolerance metabolites in overwintering adult mountain pine beetles
- Management of veterinary anaesthesia in small animals: A survey of current practice in Quebec
- Genetic structure of the European hedgehog (Erinaceus europaeus) in Denmark
- Molecular karyotyping of Siberian wild rye (Elymus sibiricus L.) with oligonucleotide fluorescence in situ hybridization (FISH) probes
- Umbilical cord separation time, predictors and healing complications in newborns with dry care
- The strain distribution in the lumbar anterior longitudinal ligament is affected by the loading condition and bony features: An in vitro full-field analysis
- Marine resource congestion in China: Identifying, measuring, and assessing its impact on sustainable development of the marine economy
- Analysis of attitudinal components towards statistics among students from different academic degrees
- Effects of fatigue induced by repeated-sprint on kicking accuracy and velocity in female soccer players
- A pre-clinical validation plan to evaluate analytical sensitivities of molecular diagnostics such as BD MAX MDR-TB, Xpert MTB/Rif Ultra and FluoroType MTB
- Leadership for success in transforming medical abortion policy in Canada
- Clinical correlates associated with the long-term response of bipolar disorder patients to lithium, valproate or lamotrigine: A retrospective study
- Determinants of change in long-acting or permanent contraceptives use in Ethiopia; A multivariate decomposition analysis of data from the Ethiopian demographic and health survey
- Forecasting stock prices with long-short term memory neural network based on attention mechanism
- On the genus Crossaster (Echinodermata: Asteroidea) and its distribution
- Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds
- Serum amyloid P component promotes formation of distinct aggregated lysozyme morphologies and reduces toxicity in Drosophila flies expressing F57I lysozyme
- Optogenetically induced cellular habituation in non-neuronal cells
- An integrated vitamin E-coated polymer hybrid nanoplatform: A lucrative option for an enhanced in vitro macrophage retention for an anti-hepatitis B therapeutic prospect
- The effect of strontium and silicon substituted hydroxyapatite electrochemical coatings on bone ingrowth and osseointegration of selective laser sintered porous metal implants
- Modeling the Theory of Planned Behaviour to predict adherence to preventive dental visits in preschool children
- Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma species in dogs with hemangiosarcoma from across the United States
- Color discrimination and gas chromatography-mass spectrometry fingerprint based on chemometrics analysis for the quality evaluation of Schizonepetae Spica
- Comparisons of recurrence-free survival and overall survival between microwave versus radiofrequency ablation treatment for hepatocellular carcinoma: A multiple centers retrospective cohort study with propensity score matching
- Transcriptome-wide identification of novel circular RNAs in soybean in response to low-phosphorus stress
- Oral misoprostol, low dose vaginal misoprostol, and vaginal dinoprostone for labor induction: Randomized controlled trial
- The association between dietary patterns before and in early pregnancy and the risk of gestational diabetes mellitus (GDM): Data from the Malaysian SECOST cohort
- Gene expression noise in a complex artificial toxin expression system
- Dynamic Extreme Aneuploidy (DEA) in the vegetable pathogen Phytophthora capsici and the potential for rapid asexual evolution
- Assertive, trainable and older dogs are perceived as more dominant in multi-dog households
- Prediction of Uropathogens by Flow Cytometry and Dip-stick Test Results of Urine Through Multivariable Logistic Regression Analysis
- Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2
- Copper to Tuscany – Coals to Newcastle? The dynamics of metalwork exchange in early Italy
- The Brazilian TP53 mutation (R337H) and sarcomas
- Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance
- Detection of amitraz resistance and reduced treatment efficacy in the Varroa Mite, Varroa destructor, within commercial beekeeping operations
- Impact of viral disease hypophagia on pig jejunal function and integrity
- Enzyme response of activated sludge to a mixture of emerging contaminants in continuous exposure
- Molecular evidence for horizontal transmission of chelonid alphaherpesvirus 5 at green turtle (Chelonia mydas) foraging grounds in Queensland, Australia
- Technology anxiety and resistance to change behavioral study of a wearable cardiac warming system using an extended TAM for older adults
- Evaluation and validation of 2D biomechanical models of the knee for radiograph-based preoperative planning in total knee arthroplasty
- Soil-Transmitted Helminth infections reduction in Bhutan: A report of 29 years of deworming
- Age-related differences in the temporal dynamics of spectral power during memory encoding
- cagA gene EPIYA motif genetic characterization from Colombian Helicobacter pylori isolates: Standardization of a molecular test for rapid clinical laboratory detection
- Mugharat an-Nachcharini: A specialized sheep-hunting camp reveals high-altitude habitats in the earliest Neolithic of the Central Levant
- Spectral characteristics of urine from patients with end-stage kidney disease analyzed using Raman Chemometric Urinalysis (Rametrix)
- Clinicians’ communication with patients receiving a MCI diagnosis: The ABIDE project
- Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling
- Fast quantitative time lapse displacement imaging of endothelial cell invasion
- Two novel mutations in MSX1 causing oligodontia
- 7,200 years old constructions and mudbrick technology: The evidence from Tel Tsaf, Jordan Valley, Israel
- Tuberculosis recurrences and predictive factors in a vulnerable population in Catalonia
- Dome-shaped macula in children and adolescents
- Barriers in the access, diagnosis and treatment completion for tuberculosis patients in central and western Nepal: A qualitative study among patients, community members and health care workers
- Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer
- Targeted transcriptomic study of the implication of central metabolic pathways in mannosylerythritol lipids biosynthesis in Pseudozyma antarctica T-34
- Preliminary evidences of the presence of extracellular DNA single stranded forms in soil
- A comparison of quality of life between patients treated with different dialysis modalities in Taiwan
- The effectiveness of substance use interventions for homeless and vulnerably housed persons: A systematic review of systematic reviews on supervised consumption facilities, managed alcohol programs, and pharmacological agents for opioid use disorder
- Spatiotemporal characteristics and driving forces of construction land expansion in Yangtze River economic belt, China
- Comparison of Monocyte Distribution Width (MDW) and Procalcitonin for early recognition of sepsis
- Morphological association between the muscles and bones in the craniofacial region
- Transcriptome analysis of Actinidia chinensis in response to Botryosphaeria dothidea infection
- Evaluating two decision aids for Australian men supporting informed decisions about prostate cancer screening: A randomised controlled trial
- Serum galectins as potential biomarkers of inflammatory bowel diseases
- Linguistic Z-number weighted averaging operators and their application to portfolio selection problem
- Comparative study on skin protection activity of polyphenol-rich extract and polysaccharide-rich extract from Sargassum vachellianum
- Real-world data about emotional stress, disability and need for social care in a German IBD patient cohort
- The regenerative compatibility: A synergy between healthy ecosystems, environmental attitudes, and restorative experiences
- Fusion of augmented reality imaging with the endoscopic view for endonasal skull base surgery; a novel application for surgical navigation based on intraoperative cone beam computed tomography and optical tracking
- Functional characterization of NK cells in Mexican pediatric patients with acute lymphoblastic leukemia: Report from the Mexican Interinstitutional Group for the Identification of the Causes of Childhood Leukemia
- Radiomics signature for prediction of lateral lymph node metastasis in conventional papillary thyroid carcinoma
- Antenatal depression and its association with adverse birth outcomes in low and middle-income countries: A systematic review and meta-analysis
- Perceptions of risk and influences of choice in pregnant women with obesity. An evidence synthesis of qualitative research
- The role of refugee and migrant migration status on medication adherence: Mediation through illness perceptions
- Job stress and emotional exhaustion at work in Spanish workers: Does unhealthy work affect the decision to drive?
- Correction: Amphibians on the hotspot: Molecular biology and conservation in the South American Atlantic Rainforest
- Sexual risk classes among youth experiencing homelessness: Relation to childhood adversities, current mental symptoms, substance use, and HIV testing
- Time for change is now: Experiences of participants in a community-based approach for iron and folic acid supplementation in a rural county in Kenya, a qualitative study
- Non-invasive genetic monitoring for the threatened valley elderberry longhorn beetle
- Statistical learning for turboshaft helicopter accidents using logistic regression
- Vegetation change over seven years in the largest protected Pacific Northwest Bunchgrass Prairie remnant
- The effect of various metal-salts on the sedimentation of soil in a water-based suspension
- Using electronic health record system triggers to target delivery of a patient-centered intervention to improve venous thromboembolism prevention for hospitalized patients: Is there a differential effect by race?
- Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells
- Novel broad-spectrum activity-based probes to profile malarial cysteine proteases
- Health-related quality of life in cancer patients treated with immune checkpoint inhibitors: A systematic review on reporting of methods in randomized controlled trials
- Environmental tobacco smoke (ETS) and hyperlipidemia modified by perceived work stress
- Association between opioid analgesic therapy and initiation of buprenorphine management: An analysis of prescription drug monitoring program data
- Effect of a community-based approach of iron and folic acid supplementation on compliance by pregnant women in Kiambu County, Kenya: A quasi-experimental study
- Radiocarbon dating of two old African baobabs from India
- Improvement project in higher education institutions: A BPEP-based model
- An updated evaluation of serum sHER2, CA15.3, and CEA levels as biomarkers for the response of patients with metastatic breast cancer to trastuzumab-based therapies
- Genome-wide association study of metabolic syndrome in Korean populations
- The diagnostic accuracy of liver fibrosis in non-viral liver diseases using acoustic radiation force impulse elastography: A systematic review and meta-analysis
- Drug therapy problems and treatment satisfaction among ambulatory patients with epilepsy in a specialized hospital in Ethiopia
- Short- & long-term effects of monetary and non-monetary incentives to cooperate in public good games: An experiment
- Niche modeling reveals life history shifts in birds at La Brea over the last twenty millennia
- Morphological consequences of artificial cranial deformation: Modularity and integration
- Distributed flux balance analysis simulations of serial biomass fermentation by two organisms
- Plasma kynurenines and prognosis in patients with heart failure
- Occurrence and distribution of anthropogenic persistent organic pollutants in coastal sediments and mud shrimps from the wetland of central Taiwan
- Intensified visual clutter induces increased sympathetic signalling, poorer postural control, and faster torsional eye movements during visual rotation
- Restoration of cortical symmetry and binaural function: Cortical auditory evoked responses in adult cochlear implant users with single sided deafness
- A smartphone-enabled wireless and batteryless implantable blood flow sensor for remote monitoring of prosthetic heart valve function
- Gut microbiota composition alterations are associated with the onset of diabetes in kidney transplant recipients
- Shock index and TIMI risk index as valuable prognostic tools in patients with acute coronary syndrome complicated by cardiogenic shock
- Merit overrules theory of mind when young children share resources with others
- Economic burden of maternal morbidity – A systematic review of cost-of-illness studies
- Comparison of balance changes after inspiratory muscle or Otago exercise training
- Correction: Escherichia coli and Salmonella spp. isolated from Australian meat chickens remain susceptible to critically important antimicrobial agents
- Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue
- Cell-free DNA donor fraction analysis in pediatric and adult heart transplant patients by multiplexed allele-specific quantitative PCR: Validation of a rapid and highly sensitive clinical test for stratification of rejection probability
- Immunopathogenesis of canine chronic ulcerative stomatitis
- Correction: Quantification of speech and synchrony in the conversation of adults with autism spectrum disorder
- Efficacy and safety of ultrasonic circular cyclocoagulation with second-generation probe in glaucoma: A retrospective study
- Generalizing findings from a randomized controlled trial to a real-world study of the iLookOut, an online education program to improve early childhood care and education providers’ knowledge and attitudes about reporting child maltreatment
- Self-selection of food ingredients and agricultural by-products by the house cricket, Acheta domesticus (Orthoptera: Gryllidae): A holistic approach to develop optimized diets
- Machine learning detection of Atrial Fibrillation using wearable technology
- Comparative proteomic analysis of different stages of breast cancer tissues using ultra high performance liquid chromatography tandem mass spectrometer
- A cross-sectional study of psychopathy and khat abuse among prisoners in the correctional institution in Jimma, Ethiopia
- Head impulse compensatory saccades: Visual dependence is most evident in bilateral vestibular loss
- Complementarity of empirical and process-based approaches to modelling mosquito population dynamics with Aedes albopictus as an example—Application to the development of an operational mapping tool of vector populations
- Pepsin promotes laryngopharyngeal neoplasia by modulating signaling pathways to induce cell proliferation
- When and what to test for: A cost-effectiveness analysis of febrile illness test-and-treat strategies in the era of responsible antibiotic use
- Comparison of effects and safety in providing controlled hypotension during surgery between dexmedetomidine and magnesium sulphate: A meta-analysis of randomized controlled trials
- The gene encoding the ketogenic enzyme HMGCS2 displays a unique expression during gonad development in mice
- Seroepidemiological study of rubella in Vojvodina, Serbia: 24 years after the introduction of the MMR vaccine in the national immunization programme
- Efficacy of a mitochondrion-targeting agent for reducing the level of urinary protein in rats with puromycin aminonucleoside-induced minimal-change nephrotic syndrome
- Association of endothelial nitric oxide synthase (NOS3) gene polymorphisms with primary open-angle glaucoma in a Saudi cohort
- Antitrust analysis with upward pricing pressure and cost efficiencies
- Machine learning models for identifying preterm infants at risk of cerebral hemorrhage
- Natural selection contributes to food web stability
- Pyramiding QTLs controlling tolerance against drought, salinity, and submergence in rice through marker assisted breeding
- Diversity and plant growth-promoting functions of diazotrophic/N-scavenging bacteria isolated from the soils and rhizospheres of two species of Solanum
- Sustainability effects of motor control stabilisation exercises on pain and function in chronic nonspecific low back pain patients: A systematic review with meta-analysis and meta-regression
- Sofosbuvir-based regimen for genotype 2 HCV infected patients in Taiwan: A real world experience
- The virulence domain of Shigella IcsA contains a subregion with specific host cell adhesion function
- Sequencing artifacts derived from a library preparation method using enzymatic fragmentation
- Analysis of the Rdr1 gene family in different Rosaceae genomes reveals an origin of an R-gene cluster after the split of Rubeae within the Rosoideae subfamily
- Concomitant phytonutrient and transcriptome analysis of mature fruit and leaf tissues of tomato (Solanum lycopersicum L. cv. Oregon Spring) grown using organic and conventional fertilizer
- Quantitative analysis of adsorption and desorption of volatile organic compounds on reusable zeolite filters using gas chromatography
- Comparing bioinformatic pipelines for microbial 16S rRNA amplicon sequencing
- TMEM98 is a negative regulator of FRAT mediated Wnt/ß-catenin signalling
- Modeling migration patterns in the USA under sea level rise
- Quo vadis Pantanal? Expected precipitation extremes and drought dynamics from changing sea surface temperature
- Cloud-computing and machine learning in support of country-level land cover and ecosystem extent mapping in Liberia and Gabon
- An exploratory study on the quality of patient screening and counseling for hypertension management in Tanzania
- Relation of fibroblast growth factor receptor 2 expression to hepatocellular carcinoma recurrence after liver resection
- The Brief Measure of Emotional Preoperative Stress (B-MEPS) as a new predictive tool for postoperative pain: A prospective observational cohort study
- The impact of diabetes mellitus medication on the incidence of endogenous endophthalmitis
- Correction: Chl1 DNA helicase and Scc2 function in chromosome condensation through cohesin deposition
- Clinical and pathological features of thrombotic microangiopathy influencing long-term kidney transplant outcomes
- Multidisciplinary investigation of two Egyptian child mummies curated at the University of Tartu Art Museum, Estonia (Late/Graeco-Roman Periods)
- Occupational exposure to particulate matter from air pollution in the outdoor workplaces in Almaty during the cold season
- Morphological adjustment in free-living Steinernema feltiae infective juveniles to increasing concentration of Nemafric-BL phytonematicide
- Murine Surf4 is essential for early embryonic development
- Using mHealth to improve health care delivery in India: A qualitative examination of the perspectives of community health workers and beneficiaries
- Algorithmic handwriting analysis of the Samaria inscriptions illuminates bureaucratic apparatus in biblical Israel
- Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis
- Concurrent lipidomics and proteomics on malignant plasma cells from multiple myeloma patients: Probing the lipid metabolome
- Short treatment with antalarmin alters adrenal gland receptors in the rat model of endometriosis
- Is it really always only the others who are to blame? GP’s view on medical overuse. A questionnaire study
- Serum visfatin and vaspin levels in hepatocellular carcinoma (HCC)
- Retraction: SDR9C7 Promotes Lymph Node Metastases in Patients with Esophageal Squamous Cell Carcinoma
- iTRAQ proteomics reveals the regulatory response to Magnaporthe oryzae in durable resistant vs. susceptible rice genotypes
- A smartphone-based test for the assessment of attention deficits in delirium: A case-control diagnostic test accuracy study in older hospitalised patients
- Association between tuberculosis and depression on negative outcomes of tuberculosis treatment: A systematic review and meta-analysis
- Incidence and predictors of loss to follow up among adult HIV patients on antiretroviral therapy in University of Gondar Comprehensive Specialized Hospital: A competing risk regression modeling
- Point-of-care diagnostic (POCD) method for detecting Bursaphelenchus xylophilus in pinewood using recombinase polymerase amplification (RPA) with the portable optical isothermal device (POID)
- Bioluminescent imaging of Arabidopsis thaliana using an enhanced Nano-lantern luminescence reporter system
- Biosynthetic pathway of indole-3-acetic acid in ectomycorrhizal fungi collected from northern Thailand
- Clinical implications of elevated serum interleukin-6 in IgG4-related disease
- Downscaling NLDAS-2 daily maximum air temperatures using MODIS land surface temperatures
- Sex-specific and opposite modulatory aspects revealed by PPI network and pathway analysis of ischemic stroke in humans
- Plasma Trimethylamine-N-oxide and impaired glucose regulation: Results from The Oral Infections, Glucose Intolerance and Insulin Resistance Study (ORIGINS)
- Self-esteem and other risk factors for depressive symptoms among adolescents in United Arab Emirates
- Control of the microsporidian parasite Nosema ceranae in honey bees (Apis mellifera) using nutraceutical and immuno-stimulatory compounds
- The effect of storage conditions on microbial communities in stool
- Role of donor genotype in RT-QuIC seeding activity of chronic wasting disease prions using human and bank vole substrates
- Influence of flow on phosphorus-dynamics and particle size in agricultural drainage ditch sediments
- A prospective, randomized, double-blind trial to compare body weight-adjusted and fixed doses of palonosetron for preventing postoperative nausea and vomiting in obese female patients
- Application of computerized 3D-CT texture analysis of pancreas for the assessment of patients with diabetes
- Predictive validation and forecasts of short-term changes in healthcare expenditure associated with changes in smoking behavior in the United States
- An information-based approach to handle various types of uncertainty in fuzzy bodies of evidence
- Oral magnesium supplementation for leg cramps in pregnancy—An observational controlled trial
- Health care professionals’ knowledge of commonly used sedative, analgesic and neuromuscular drugs: A single center (Rambam Health Care Campus), prospective, observational survey
- Campylobacter portucalensis sp. nov., a new species of Campylobacter isolated from the preputial mucosa of bulls
- OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model
- Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice
- Novel method to measure temporal windows based on eye movements during viewing of the Necker cube
- Whole blood transcriptomic analysis of beef cattle at arrival identifies potential predictive molecules and mechanisms that indicate animals that naturally resist bovine respiratory disease
- Effects of smoke flavoring using different wood chips and barbecuing on the formation of polycyclic aromatic hydrocarbons and heterocyclic aromatic amines in salmon fillets
- Sleep quality and sex modify the relationships between trait energy and fatigue on state energy and fatigue
- The role of peer, parental, and school norms in predicting adolescents’ attitudes and behaviours of majority and different minority ethnic groups in Croatia
- Filtered beauty in Oslo and Tokyo: A spatial frequency analysis of facial attractiveness
- The impact of rehabilitation frequency on the risk of stroke in patients with rheumatoid arthritis
- Availability, prices and affordability of selected antibiotics and medicines against non-communicable diseases in western Cameroon and northeast DR Congo
- The effect of mutations derived from mouse-adapted H3N2 seasonal influenza A virus to pathogenicity and host adaptation
- Detection of posttraumatic pneumothorax using electrical impedance tomography—An observer-blinded study in pigs with blunt chest trauma
- Educators’ perceptions of organisational readiness for implementation of a pre-adolescent transdisciplinary school health intervention for inter-generational outcomes
- Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA
- The effects of sport expertise and shot results on basketball players’ action anticipation
- Framework and algorithms for identifying honest blocks in blockchain
- Efficacy and safety of anti-viral therapy for Hepatitis B virus-associated glomerulonephritis: A meta-analysis
- Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10
- Noise reduction and quantification of fiber orientations in greyscale images
- Exploring the impact of terminology differences in blood and organ donor decision making
- Ontogenetic similarities between giraffe and sauropod neck osteological mobility
- Load transfer mechanism and critical length of anchorage zone for anchor bolt
- Income inequalities in stroke incidence and mortality: Trends in stroke-free and stroke-affected life years based on German health insurance data
- Community’s perception, experiences and health seeking behavior towards newborn illnesses in Debre Libanos District, North Shoa, Oromia, Ethiopia: Qualitative study
- Platelet indices significantly correlate with liver fibrosis in HCV-infected patients
- Reanalysis of the Bridge et al. study of suicide following release of 13 Reasons Why
- Validation of the easyscreen flavivirus dengue alphavirus detection kit based on 3base amplification technology and its application to the 2016/17 Vanuatu dengue outbreak
- The nitrate content of fresh and cooked vegetables and their health-related risks
- Bioreactor for mobilization of mesenchymal stem/stromal cells into scaffolds under mechanical stimulation: Preliminary results
- Serotonin transporter dependent modulation of food-seeking behavior
- Implicit task switching in Parkinson’s disease is preserved when on medication
- Root treatment with oxathiapiprolin, benthiavalicarb or their mixture provides prolonged systemic protection against oomycete foliar pathogens
- Real-world effectiveness and safety of ranibizumab for the treatment of myopic choroidal neovascularization: Results from the LUMINOUS study
- Non-gradient and genotype-dependent patterns of RSV gene expression
- Multiplex real-time PCR for the detection of Clavibacter michiganensis subsp. michiganensis, Pseudomonas syringae pv. tomato and pathogenic Xanthomonas species on tomato plants
- The 24-hour urinary cortisol in post-traumatic stress disorder: A meta-analysis
- Parasites modulate the gut-microbiome in insects: A proof-of-concept study
- The dynamics of shapes of vesicle membranes with time dependent spontaneous curvature
- Vascularization and biocompatibility of poly(ε-caprolactone) fiber mats for rotator cuff tear repair
- The shield of self-compassion: A buffer against disordered eating risk from physical appearance perfectionism
- Disease-specific out-of-pocket healthcare expenditure in urban Bangladesh: A Bayesian analysis
- Advanced biofilm analysis in streams receiving organic deicer runoff
- Upregulation of long non-coding RNA ROR1-AS1 promotes cell growth and migration in bladder cancer by regulation of miR-504
- Method development and validation for rapid identification of epigallocatechin gallate using ultra-high performance liquid chromatography
- Neonatal sepsis in Iran: A systematic review and meta-analysis on national prevalence and causative pathogens
- Drug-eluting versus bare-metal stents for first myocardial infarction in patients with atrial fibrillation: A nationwide population-based cohort study
- Same-day antiretroviral therapy initiation for HIV-infected adults in South Africa: Analysis of routine data
- Health-related quality of life among patients with type 2 diabetes mellitus in Eastern Province, Saudi Arabia: A cross-sectional study
- Photocatalytic biocidal effect of copper doped TiO2 nanotube coated surfaces under laminar flow, illuminated with UVA light on Legionella pneumophila
- The interoceptive hippocampus: Mouse brain endocrine receptor expression highlights a dentate gyrus (DG)–cornu ammonis (CA) challenge–sufficiency axis
- Educational attainment and HIV testing and counselling service utilisation during antenatal care in Ghana: Analysis of Demographic and Health Surveys
- Dissection of flag leaf metabolic shifts and their relationship with those occurring simultaneously in developing seed by application of non-targeted metabolomics
- Centromeres of Cucumis melo L. comprise Cmcent and two novel repeats, CmSat162 and CmSat189
- Acute high-intensity and moderate-intensity interval exercise do not change corticospinal excitability in low fit, young adults
- “I like the way I am, but I feel like I could get a little bit bigger”: Perceptions of body image among adolescents and youth living with HIV in Durban, South Africa
- Nanoparticle-based ‘turn-on’ scattering and post-sample fluorescence for ultrasensitive detection of water pollution in wider window
- The relationship of moral sensitivity and patient safety attitudes with nursing students’ perceptions of disclosure of patient safety incidents: A cross-sectional study
- Insights into the strategy of micro-environmental adaptation: Transcriptomic analysis of two alvinocaridid shrimps at a hydrothermal vent
- Thirty-day readmission after medical-surgical hospitalization for people who experience imprisonment in Ontario, Canada: A retrospective cohort study
- The effect of long-term brine discharge from desalination plants on benthic foraminifera
- Hyper-spectral response and estimation model of soil degradation in Kenli County, the Yellow River Delta
- Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017
- Significant changes in synovial fluid microRNAs after high tibial osteotomy in medial compartmental knee osteoarthritis: Identification of potential prognostic biomarkers
- Reassortment and adaptive mutations of an emerging avian influenza virus H7N4 subtype in China
- Ischemia and reperfusion injury in superficial inferior epigastric artery-based vascularized lymph node flaps
- High failure rates of protease inhibitor-based antiretroviral treatment in rural Tanzania – A prospective cohort study
- Switchable resolution in soft x-ray tomography of single cells
- Mitochondrial DNA variations and mitochondrial dysfunction in Fanconi anemia
- Extended-spectrum beta-lactamase (ESBL)-producing and non-ESBL-producing Escherichia coli isolates causing bacteremia in the Netherlands (2014 – 2016) differ in clonal distribution, antimicrobial resistance gene and virulence gene content
- Molecular characterization of blaKHM-1 encoding plasmid in an Enterobacter hormaechei subsp. hoffmannii isolate from blood culture
- PR3 levels are impaired in plasma and PBMCs from Arabs with cardiovascular diseases
- Sex differences in self-regulation in early, middle and late adolescence: A large-scale cross-sectional study
- Interaction between elevated temperature and different types of Na-salicylate treatment in Brachypodium dystachion
- A highway crash risk assessment method based on traffic safety state division
- A brain connectivity characterization of children with different levels of mathematical achievement based on graph metrics
- Quantifying the level of difficulty to treat major depressive disorder with antidepressants: Treatment Resistance to Antidepressants Evaluation Scale
- Occupational gender segregation and economic growth in U.S. local labor markets, 1980 through 2010
- The association of telomere length and telomerase activity with adverse outcomes in older patients with non-ST-elevation acute coronary syndrome
- Construction of a high-density genetic map and fine mapping of a candidate gene locus for a novel branched-spike mutant in barley
- Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease
- Parameters impacting the live birth rate per transfer after frozen single euploid blastocyst transfer
- Deep2Full: Evaluating strategies for selecting the minimal mutational experiments for optimal computational predictions of deep mutational scan outcomes
- Economic compensation interventions to increase uptake of voluntary medical male circumcision for HIV prevention: A systematic review and meta-analysis
- Distinctive effect of anesthetics on the effect of limb remote ischemic postconditioning following ischemic stroke
- Natural hybridization between Phyllagathis and Sporoxeia species produces a hybrid without reproductive organs
- Preliminary evaluation of a novel nine-biomarker profile for the prediction of autism spectrum disorder
- The impact of peer attachment on prosocial behavior, emotional difficulties and conduct problems in adolescence: The mediating role of empathy
- Spatial and climatic variables independently drive elevational gradients in ant species richness in the Eastern Himalaya
- What is the qualitative evidence concerning the risks, diagnosis, management and consequences of gastrointestinal infections in the community in the United Kingdom? A systematic review and meta-ethnography
- Naringenin protects AlCl3/D-galactose induced neurotoxicity in rat model of AD via attenuation of acetylcholinesterase levels and inhibition of oxidative stress
- Key barriers and enablers associated with uptake and continuation of oral pre-exposure prophylaxis (PrEP) in the public sector in Zimbabwe: Qualitative perspectives of general population clients at high risk for HIV
- Characterizing the University of California’s tenure-track teaching position from the faculty and administrator perspectives
- Restoration of Mal overcomes the defects of apoptosis in lung cancer cells
- Patient preferences for maintenance therapy in Crohn’s disease: A discrete-choice experiment
- Diagnostic performance of serum interferon gamma, matrix metalloproteinases, and periostin measurements for pulmonary tuberculosis in Japanese patients with pneumonia
- Hesperidin improves insulin resistance via down-regulation of inflammatory responses: Biochemical analysis and in silico validation
- Accuracy of intraocular lens power calculation formulas using a swept-source optical biometer
- Characterization of black patina from the Tiber River embankments using Next-Generation Sequencing
- Comparison of blood lactate and perceived exertion responses in two matched time-under-tension protocols
- Fibrin hydrogels are safe, degradable scaffolds for sub-retinal implantation
- Post-translational modifications of Drosophila melanogaster HOX protein, Sex combs reduced
- Problem gambling, associations with comorbid health conditions, substance use, and behavioural addictions: Opportunities for pathways to treatment
- Liganded T3 receptor β2 inhibits the positive feedback autoregulation of the gene for GATA2, a transcription factor critical for thyrotropin production
- Characterization of METTL16 as a cytoplasmic RNA binding protein
- Impact of long-term storage and freeze-thawing on eight circulating microRNAs in plasma samples
- Nanosheet wrapping-assisted coverslip-free imaging for looking deeper into a tissue at high resolution
- Assessment of dynamic cerebral autoregulation in humans: Is reproducibility dependent on blood pressure variability?
- Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study
- Validity of cerebrovascular ICD-9-CM codes in healthcare administrative databases. The Umbria Data-Value Project
- Tuberculoid leprosy: An in vivo microvascular evaluation of cutaneous lesions
- Neuromuscular blockers in the acute respiratory distress syndrome: A meta-analysis
- Identification of putative Type-I sex pheromone biosynthesis-related genes expressed in the female pheromone gland of Streltzoviella insularis
- Redefining transcriptional regulation of the APOE gene and its association with Alzheimer’s disease
- Disease-relevant mutations alter amino acid co-evolution networks in the second nucleotide binding domain of CFTR
- A bushel of viruses: Identification of seventeen novel putative viruses by RNA-seq in six apple trees
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- The variability of bacterial communities in both the endosphere and ectosphere of different niches in Chinese chives (Allium tuberosum)
- Tripartite factors leading to molecular divergence between human and murine smooth muscle
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- A scoping review of importation and predictive models related to vector-borne diseases, pathogens, reservoirs, or vectors (1999–2016)
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- Associations of cigarette smoking and burden of thoracic aortic calcification in asymptomatic individuals: A dose-response relationship
- Healthcare utilization of Mexican-American Medicare beneficiaries with and without Alzheimer’s disease and related dementias
- Evaluation of questionnaire as an instrument to measure the level of nutritional and weight gain knowledge in pregnant women in Poland. A pilot study
- TranCEP: Predicting the substrate class of transmembrane transport proteins using compositional, evolutionary, and positional information
- Non-Invasive Functional-Brain-Imaging with an OPM-based Magnetoencephalography System
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- Transforming assessment of speech in children with cleft palate via online crowdsourcing
- High prevalence of off-label and unlicensed paediatric prescribing in a hospital in Indonesia during the period Aug.—Oct. 2014
- General practice management of rotator cuff related shoulder pain: A reliance on ultrasound and injection guided care
- Estimating the population size of female sex workers and transgender women in Sri Lanka
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- A two-arm parallel double-blind randomised controlled pilot trial of the efficacy of Omega-3 polyunsaturated fatty acids for the treatment of women with endometriosis-associated pain (PurFECT1)
- Association of benzodiazepines, opioids and tricyclic antidepressants use and falls in trauma patients: Conditional effect of age
- Burden and risk factors of cutaneous leishmaniasis in a peri-urban settlement in Kenya, 2016
- Predicting strike susceptibility and collision patterns of the common buzzard at wind turbine structures in the federal state of Brandenburg, Germany
- Embryonic thermal manipulation has short and long-term effects on the development and the physiology of the Japanese quail
- High-order radiomics features based on T2 FLAIR MRI predict multiple glioma immunohistochemical features: A more precise and personalized gliomas management
- Human-raptor conflict in rural settlements of Colombia
- Regional adaptations and parallel mutations in Feline panleukopenia virus strains from China revealed by nearly-full length genome analysis
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- Adverse drug reaction reporting practice and associated factors among medical doctors in government hospitals in Addis Ababa, Ethiopia
- TaWAK6 encoding wall-associated kinase is involved in wheat resistance to leaf rust similar to adult plant resistance
- Deficiency syndromes in top predators associated with large-scale changes in the Baltic Sea ecosystem
- The inhibitor of apoptosis proteins antagonist Debio 1143 promotes the PD-1 blockade-mediated HIV load reduction in blood and tissues of humanized mice
- Allele specific expression of Dof genes responding to hormones and abiotic stresses in sugarcane
- Perceived relative social status and cognitive load influence acceptance of unfair offers in the Ultimatum Game
- Quantitative evaluation of choriocapillaris using optical coherence tomography and optical coherence tomography angiography in patients with central serous chorioretinopathy after half-dose photodynamic therapy
- Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties
- Extracting lung function measurements to enhance phenotyping of chronic obstructive pulmonary disease (COPD) in an electronic health record using automated tools
- Multiple fragmented habitat-patch use in an urban breeding passerine, the Short-toed Treecreeper
- Histological and immunohistochemical characterization of the porcine ocular surface
- Household environmental tobacco smoke exposure in healthy young children in Hong Kong: Prevalence and risk factors
- Wind energy development and wildlife conservation in Lithuania: A mapping tool for conflict assessment
- Characteristics and prognosis of primary treatment-naïve oral cavity squamous cell carcinoma in Norway, a descriptive retrospective study
- Effect of epoch length on intensity classification and on accuracy of measurement under controlled conditions on treadmill: Towards a better understanding of accelerometer measurement
- Peer distribution of HIV self-test kits to men who have sex with men to identify undiagnosed HIV infection in Uganda: A pilot study
- Error rates of human reviewers during abstract screening in systematic reviews
- Faecal analyses and alimentary tracers reveal the foraging ecology of two sympatric bats
- Urethral realignment with maximal urethral length and bladder neck preservation in robot-assisted radical prostatectomy: Urinary continence recovery
- Error metrics determination in functionally approximated circuits using SAT solvers
- Spatial movement pattern recognition in soccer based on relative player movements
- A novel visual ranking system based on arterial spin labeling perfusion imaging for evaluating perfusion disturbance in patients with ischemic stroke
- Prospective Validation of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) Score for Necrotizing Fasciitis of the Extremities
- The importance of transporters and cell polarization for the evaluation of human stem cell-derived hepatic cells
- Incidence, trends, and outcomes of infection sites among hospitalizations of sepsis: A nationwide study
- Morphological and functional characteristics of mitral annular calcification and their relationship to stroke
- And the nominees are: Using design-awards datasets to build computational aesthetic evaluation model
- Service delivery interventions to increase uptake of voluntary medical male circumcision for HIV prevention: A systematic review
- Multidimensional Scales of Perceived Self-Efficacy (MSPSE): Measurement invariance across Italian and Colombian adolescents
- Diversity of Mycobacteriaceae from aquatic environment at the São Paulo Zoological Park Foundation in Brazil
- A graph-based algorithm for RNA-seq data normalization
- Parents’ underestimation of their child’s weight status. Moderating factors and change over time: A cross-sectional study
- Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs
- Spatial variation in fertilizer prices in Sub-Saharan Africa
- Knowledge, beliefs, and concerns about bone health from a systematic review and metasynthesis of qualitative studies
- Successful isolation of Treponema pallidum strains from patients’ cryopreserved ulcer exudate using the rabbit model
- Effects of size and elasticity on the relation between flow velocity and wall shear stress in side-wall aneurysms: A lattice Boltzmann-based computer simulation study
- Pupil response to noxious corneal stimulation
- Incidence, risk factors and healthcare costs of central line-associated nosocomial bloodstream infections in hematologic and oncologic patients
- The impact of computed radiography and teleradiology on patients’ diagnosis and treatment in Mweso, the Democratic Republic of Congo
- Differential effects of synthetic psychoactive cathinones and amphetamine stimulants on the gut microbiome in mice
- Hepatitis B and C virus infection among HIV patients within the public and private healthcare systems in Chile: A cross-sectional serosurvey
- Increased episodes of aspiration on videofluoroscopic swallow study in children with nasogastric tube placement
- Obstructive sleep apnea and hypopnea syndrome in patients admitted in a tertiary hospital in Cameroon: Prevalence and associated factors
- Association of single nucleotide polymorphisms with dyslipidemia in antiretroviral exposed HIV patients in a Ghanaian population: A case-control study
- Sonic Hedgehog upregulation does not enhance the survival and engraftment of stem cell-derived cardiomyocytes in infarcted hearts
- The pharmacokinetic parameters and the effect of a single and repeated doses of memantine on gastric myoelectric activity in experimental pigs
- Blind method for discovering number of clusters in multidimensional datasets by regression on linkage hierarchies generated from random data
- Predictive factors of first dosage intravenous immunoglobulin-related adverse effects in children
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- Individual and community level determinants of short birth interval in Ethiopia: A multilevel analysis
- Effects of rejection intensity and rejection sensitivity on social approach behavior in women
- The impact of IoT security labelling on consumer product choice and willingness to pay
- The development and validation of a measurement instrument to investigate determinants of health care utilisation for low back pain in Ethiopia
- Validity of the French version of the Autonomy Preference Index and its adaptation for patients with advanced cancer
- The epidemiological characteristics and spatio-temporal analysis of childhood hand, foot and mouth disease in Korea, 2011-2017
- Exponential random graph model parameter estimation for very large directed networks
- The implementation of community-based diabetes and hypertension management care program in Indonesia
- Effect of temperature variation on hospital admissions and outcomes in dogs with myxomatous mitral valve disease and new onset pulmonary edema
- The development of the Police Practices Scale: Understanding policing approaches towards street-based female sex workers in a U.S. City
- A capability approach to assess aquaculture sustainability standard compliance
- Pre-collecting lymphatic vessels form detours following obstruction of lymphatic flow and function as collecting lymphatic vessels
- Construct validity and reliability of the Talent Development Environment Questionnaire in Caribbean youth track and field athletes
- Optimization of cytotoxic activity of Nocardia sp culture broths using a design of experiments
- Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo
- Microbiota in foods from Inuit traditional hunting
- Investigating Italian disinformation spreading on Twitter in the context of 2019 European elections
- In vivo expression of peptidylarginine deiminase in Drosophila melanogaster
- Modelling zero-truncated overdispersed antenatal health care count data of women in Bangladesh
- Detection and density of breeding marsh birds in Iowa wetlands
- A lineage-specific rapid diagnostic test (Chagas Sero K-SeT) identifies Brazilian Trypanosoma cruzi II/V/VI reservoir hosts among diverse mammalian orders
- Aromatase deficiency in hematopoietic cells improves glucose tolerance in male mice through skeletal muscle-specific effects
- If host is refractory, insistent parasite goes berserk: Trypanosomatid Blastocrithidia raabei in the dock bug Coreus marginatus
- Antimicrobial resistance patterns and molecular resistance markers of Campylobacter jejuni isolates from human diarrheal cases
- Protective role of brain derived neurotrophic factor (BDNF) in obstructive sleep apnea syndrome (OSAS) patients
- An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury
- Prevalence of antiphospholipid antibodies in Behçet's disease: A systematic review and meta-analysis
- Chemical analysis of snus products from the United States and northern Europe
- Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry
- Impact of early-onset persistent stunting on cognitive development at 5 years of age: Results from a multi-country cohort study
- Aggregation of CAT tails blocks their degradation and causes proteotoxicity in S. cerevisiae
- Expression of concern: Compensatory increase of transglutaminase 2 is responsible for resistance to mTOR inhibitor treatment
- Common mental illness among epilepsy patients in Bahir Dar city, Ethiopia: A cross-sectional study
- Staging dementia based on caregiver reported patient symptoms: Implications from a latent class analysis
- Health-related quality of life and its determinants among ambulatory patients with epilepsy at Ambo General Hospital, Ethiopia: Using WHOQOL-BREF
- In silico analysis and high-risk pathogenic phenotype predictions of non-synonymous single nucleotide polymorphisms in human Crystallin beta A4 gene associated with congenital cataract
- Fungal diversity in canopy soil of silver beech, Nothofagus menziesii (Nothofagaceae)
- Referral decisions and its predictors related to orthopaedic care. A retrospective study in a novel primary care setting
- Readiness to prescribe: Using educational design to untie the Gordian Knot
- Influence of gelation on the retention of purple cactus pear extract in microencapsulated double emulsions
- Factors related to met needs for rehabilitation 6 years after stroke
- Association of cataract and sun exposure in geographically diverse populations of India: The CASE study. First Report of the ICMR-EYE SEE Study Group
- Investigation of injury severity in urban expressway crashes: A case study from Beijing
- Clinical outcomes of incident peritoneal dialysis patients coming from kidney transplantation program: A case-control study
- Evaluation of the factors influencing the housing safety awareness of residents in Shanghai
- Morphometric study of the diaphragmatic surface of the liver in the human fetus
- Food insecurity and dietary diversity among lactating mothers in the urban municipality in the mountains of Nepal
- Genetic characterization of Bacillus anthracis strains circulating in Italy from 1972 to 2018
- Promising antifungal activity of new oxadiazole against Candida krusei
- An atlas of personality, emotion and behaviour
- Long-term effects of intracranial islet grafting on cognitive functioning in a rat metabolic model of sporadic Alzheimer's disease-like dementia
- Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor
- Comparison of the myometrial transcriptome from singleton and twin pregnancies by RNA-Seq
- Adverse reproductive effects of S100A9 on bovine sperm and early embryonic development in vitro
- Functional dynamics of bacterial species in the mouse gut microbiome revealed by metagenomic and metatranscriptomic analyses
- Astrocyte senescence promotes glutamate toxicity in cortical neurons
- Primary ciliary dyskinesia and psychological well-being in adolescence
- Dipeptidyl peptidase-4 is increased in the abdominal aortic aneurysm vessel wall and is associated with aneurysm disease processes
- Primary care physician knowledge, attitudes, and diagnostic testing practices for norovirus and acute gastroenteritis
- Microfluidic-prepared DOTAP nanoparticles induce strong T-cell responses in mice
- Intraocular scattering as a predictor of driving performance in older adults with cataracts
- Reduced bone mineral density among HIV infected patients on anti-retroviral therapy in Blantyre, Malawi: Prevalence and associated factors
- Correction: Extraversion personality, perceived health and activity participation among community-dwelling aging adults in Hong Kong
- A rainwater control optimization design approach for airports based on a self-organizing feature map neural network model
- Influence of inflammasome NLRP3, and IL1B and IL2 gene polymorphisms in periodontitis susceptibility
- 18F-FDG-PET/MRI in the diagnostic work-up of limbic encephalitis
- The socioeconomic impact of orthopaedic trauma: A systematic review and meta-analysis
- Treatment patterns among patients with moderate-to-severe ulcerative colitis in the United States and Europe
- City to city learning and knowledge exchange for climate resilience in southern Africa
- Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer
- Activity-dependent switches between dynamic regimes of extracellular matrix expression
- Molecular sequencing and morphological identification reveal similar patterns in native bee communities across public and private grasslands of eastern North Dakota
- A mathematical model for assessing the effectiveness of controlling relapse in Plasmodium vivax malaria endemic in the Republic of Korea
- Cryo-focused ion beam preparation of perovskite based solar cells for atom probe tomography
- Physiological and transcriptomic responses of Lanzhou Lily (Lilium davidii, var. unicolor) to cold stress
- Unusual genome expansion and transcription suppression in ectomycorrhizal Tricholoma matsutake by insertions of transposable elements
- Estimating associations between antidepressant use and incident mild cognitive impairment in older adults with depression
- The use of telephone communication between nurse navigators and their patients
- CNP mediated selective toxicity on melanoma cells is accompanied by mitochondrial dysfunction
- HIV RNA measurement in dried blood spots of HIV-infected patients in Thailand using Abbott m2000 system
- Retraction: Oncogenic Fibulin-5 Promotes Nasopharyngeal Carcinoma Cell Metastasis through the FLJ10540/AKT Pathway and Correlates with Poor Prognosis
- Ultra-rapid cooling of ibex sperm by spheres method does not induce a vitreous extracellular state and increases the membrane damages
- Some animals are more equal than others: Validation of a new scale to measure how attitudes to animals depend on species and human purpose of use
- Observation and quantification of the morphological effect of trypan blue rupturing dead or dying cells
- The visual perception of emotion from masks
- Hexavalent chromium removal and total chromium biosorption from aqueous solution by Quercus crassipes acorn shell in a continuous up-flow fixed-bed column: Influencing parameters, kinetics, and mechanism
- The predictive value of anthropometric indices for cardiometabolic risk factors in Chinese children and adolescents: A national multicenter school-based study
- Lean back and wait for the alarm? Testing an automated alarm system for nosocomial outbreaks to provide support for infection control professionals
- Regional disparities in health care resources in traditional Chinese medicine county hospitals in China
- Analysis on hydraulic characteristics of improved sandy soil with soft rock
- Development and use of a scale to assess gender differences in appraisal of mistreatment during childbirth among Ethiopian midwifery students
- Factors for starting biosimilar TNF inhibitors in patients with rheumatic diseases in the real world
- Correction: Force field generalization and the internal representation of motor learning
- Prevalence and foetomaternal effects of iron deficiency anaemia among pregnant women in Lagos, Nigeria
- Socioeconomic risk factors for fatal opioid overdoses in the United States: Findings from the Mortality Disparities in American Communities Study (MDAC)
- Microbiome signatures in neonatal central line associated bloodstream infections
- Interventions for incarcerated adults with opioid use disorder in the United States: A systematic review with a focus on social determinants of health
- Opening gap width influences distal tibial rotation below the osteotomy site following open wedge high tibial osteotomy
- The impact of lowbush blueberry (Vaccinium angustifolium Ait.) and cranberry (Vaccinium macrocarpon Ait.) pollination on honey bee (Apis mellifera L.) colony health status
- Surveys of knowledge and awareness of antibiotic use and antimicrobial resistance in general population: A systematic review
- Managerial capacity among district health managers and its association with district performance: A comparative descriptive study of six districts in the Eastern Region of Ghana
- Knee joint distraction in regular care for treatment of knee osteoarthritis: A comparison with clinical trial data
- Reconstruction of a regulated two-cell metabolic model to study biohydrogen production in a diazotrophic cyanobacterium Anabaena variabilis ATCC 29413
- Cochlear dysfunction is associated with styrene exposure in humans
- Intra-individual variation of particles in exhaled air and of the contents of Surfactant protein A and albumin
- Revisits, readmissions, and outcomes for pediatric traumatic brain injury in California, 2005-2014
- Enhanced handover mechanism using mobility prediction in wireless networks
- Association between regular exercise and asthma control among adults: The population-based Northern Finnish Asthma Study
- Pharyngeal microbiome alterations during Neisseria gonorrhoeae infection
- Assessment of the clinical utility of four NGS panels in myeloid malignancies. Suggestions for NGS panel choice or design
- Assessment of time management practice and associated factors among primary hospitals employees in north Gondar, northwest Ethiopia
- Genetic diversity and population structure of feral rapeseed (Brassica napus L.) in Japan
- Are the current gRNA ranking prediction algorithms useful for genome editing in plants?
- Difference between physical therapist estimation and psychological patient-reported outcome measures in patients with low back pain
- Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness
- Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies
- Investigating cumulative effects of pre-performance routine interventions in beach volleyball serving
- Dispensing of antibiotics without prescription and associated factors in drug retail outlets of Eritrea: A simulated client method
- MicroRNA expression and DNA methylation profiles do not distinguish between primary and recurrent well-differentiated liposarcoma
- Assessment of acyl-CoA cholesterol acyltransferase (ACAT-1) role in ovarian cancer progression—An in vitro study
- Cytoplasmic factories, virus assembly, and DNA replication kinetics collectively constrain the formation of poxvirus recombinants
- The wavelet power spectrum of perfusion weighted MRI correlates with tumor vascularity in biopsy-proven glioblastoma samples
- Agreement between cardiovascular disease risk assessment tools: An application to the United Arab Emirates population
- Constructing HLM to examine multi-level poverty-contributing factors of farmer households: Why and how?
- Patterns of symptoms possibly indicative of cancer and associated help-seeking behaviour in a large sample of United Kingdom residents—The USEFUL study
- An automated alarm system for food safety by using electronic invoices
- Neural effects of acute stress on appetite: A magnetoencephalography study
- Use of magnetic resonance imaging to determine laterality of meniscal size in healthy volunteers
- Co-prevalence of extracranial carotid aneurysms differs between European intracranial aneurysm cohorts
- Thermal biology of two tropical lizards from the Ecuadorian Andes and their vulnerability to climate change
- When weight is an encumbrance; avoidance of stairs by different demographic groups
- Non-mycosis fungoides cutaneous lymphomas in a referral center in Taiwan: A retrospective case series and literature review
- From the host's point of view: Effects of variation in burying beetle brood care and brood size on the interaction with parasitic mites
- Kernel-based Gaussian process for anomaly detection in sparse gamma-ray data
- Unmet care needs of children with ADHD
- Accelerometer-assessed outdoor physical activity is associated with meteorological conditions among older adults: Cross-sectional results from the OUTDOOR ACTIVE study
- Identification of Korean cancer survivors’ unmet needs and desired psychosocial assistance: A focus group study
- Evaluation of inactivated Bordetella pertussis as a delivery system for the immunization of mice with Pneumococcal Surface Antigen A
- The role of moral reasoning & personality in explaining lyrical preferences
- Would you like to participate in this trial? The practice of informed consent in intrapartum research in the last 30 years
- Correction: Mutation spectrums of TSC1 and TSC2 in Chinese women with lymphangioleiomyomatosis (LAM)
- Forward lunge before and after anterior cruciate ligament reconstruction: Faster movement but unchanged knee joint biomechanics
- Challenges associated with homologous directed repair using CRISPR-Cas9 and TALEN to edit the DMD genetic mutation in canine Duchenne muscular dystrophy
- Integrated targeted serum metabolomic profile and its association with gender, age, disease severity, and pattern identification in acne
- A prospective case-control study on miRNA circulating levels in subjects born small for gestational age (SGA) evaluated from childhood into young adulthood
- Polymer-fiber-coupled field-effect sensors for label-free deep brain recordings
- Global depth perception alters local timing sensitivity
- How to detect a polytrauma patient at risk of complications: A validation and database analysis of four published scales
- Module for SWC neuron morphology file validation and correction enabled for high throughput batch processing
- Reduced gray matter volume and cortical thickness associated with traffic-related air pollution in a longitudinally studied pediatric cohort
- Recombinant human soluble thrombomodulin is associated with attenuation of sepsis-induced renal impairment by inhibition of extracellular histone release
- Human and climatic drivers affect spatial fishing patterns in a multiple-use marine protected area: The Galapagos Marine Reserve
- Correction: Leisure-time physical activity and sports in the Brazilian population: A social disparity analysis
- Application of the mixture item response theory model to the Self-Administered Food Security Survey Module for Children
- Numerical simulation of atmospheric CO2 concentration and flux over the Korean Peninsula using WRF-VPRM model during Korus-AQ 2016 campaign
- Feline irradiated diet-induced demyelination; a model of the neuropathology of sub-acute combined degeneration?
- Improved multi-parametric prediction of tissue outcome in acute ischemic stroke patients using spatial features
- Genome-wide association and epistatic interactions of flowering time in soybean cultivar
- Correction: Association between workplace bullying and burnout, professional quality of life, and turnover intention among clinical nurses
- Correction: Estimation of membrane bending modulus of stiffness tuned human red blood cells from micropore filtration studies
- Correction: Limited indirect effects of an infant pneumococcal vaccination program in an aging population
- Correction: Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats
- Fieldwork-based determination of design priorities for point-of-use drinking water quality sensors for use in resource-limited environments
- Young women’s reproductive health conversations: Roles of maternal figures and clinical practices
- Correction: Differential recordings of local field potential: A genuine tool to quantify functional connectivity
- Survival of medial versus lateral unicompartmental knee arthroplasty: A meta-analysis
- Novel MscL agonists that allow multiple antibiotics cytoplasmic access activate the channel through a common binding site
- Is it time to stop sweeping data cleaning under the carpet? A novel algorithm for outlier management in growth data
- Changes in oak (Quercus robur) photosynthesis after winter moth (Operophtera brumata) herbivory are not explained by changes in chemical or structural leaf traits
- Mutual interaction between motor cortex activation and pain in fibromyalgia: EEG-fNIRS study
- Evaluation of liposomal ciprofloxacin formulations in a murine model of anthrax
- Analysis of cholesterol in mouse brain by HPLC with UV detection
- Sugar, amino acid and inorganic ion profiling of the honeydew from different hemipteran species feeding on Abies alba and Picea abies
- Exploring prior diseases associated with incident late-onset Alzheimer’s disease dementia
- Hypertension prevalence in patients attending tertiary pain management services, a registry-based Australian cohort study
- SRL pathogenicity island contributes to the metabolism of D-aspartate via an aspartate racemase in Shigella flexneri YSH6000
- Correction: Comprehensive genome-wide analysis of the pear (Pyrus bretschneideri) laccase gene (PbLAC) family and functional identification of PbLAC1 involved in lignin biosynthesis
- Epilepsy in a melanocyte-lineage mTOR hyperactivation mouse model: A novel epilepsy model
- Water consumption and prevalence of irritable bowel syndrome among adults
- Mixed evidence for the relationship between periodontitis and Alzheimer’s disease: A bidirectional Mendelian randomization study
- Correction: Health conditions associated with overweight in climacteric women
- Correction: Determining Glomerular Filtration Rate in Homozygous Sickle Cell Disease: Utility of Serum Creatinine Based Estimating Equations
- Modelling the number of antenatal care visits in Bangladesh to determine the risk factors for reduced antenatal care attendance
- Correction: Cumulative viral load as a predictor of CD4+ T-cell response to antiretroviral therapy using Bayesian statistical models
- Dominant negative effects by inactive Spa47 mutants inhibit T3SS function and Shigella virulence
- ICOS-deficient and ICOS YF mutant mice fail to control Toxoplasma gondii infection of the brain
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- Life history of northern Gulf of Mexico Warsaw grouper Hyporthodus nigritus inferred from otolith radiocarbon analysis
- Physiology education for intensive care medicine residents: A 15-minute interactive peer-led flipped classroom session
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- Comparative pharmacokinetics and pharmacodynamics of the advanced Retinol-Binding Protein 4 antagonist in dog and cynomolgus monkey
- Correction: A handy method to remove bacterial contamination from fungal cultures
- Correction: Effect of statin on life prognosis in Japanese patients undergoing hemodialysis
- Retraction: Outer Membrane Protein A (OmpA) of Shigella flexneri 2a Induces TLR2-Mediated Activation of B Cells: Involvement of Protein Tyrosine Kinase, ERK and NF-κB
- Retraction: Biofabrication of streptomycin-conjugated calcium phosphate nanoparticles using red ginseng extract and investigation of their antibacterial potential
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- Correction: Drivers of deforestation in the basin of the Usumacinta River: Inference on process from pattern analysis using generalised additive models
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- Retraction: MiR-30a-5p Antisense Oligonucleotide Suppresses Glioma Cell Growth by Targeting SEPT7
- Correction: Dynamics of plasma micronutrient concentrations and their correlation with serum proteins and thyroid hormones in patients with paracoccidioidomycosis
- Impact of lower limb osteoarthritis on health-related quality of life: A cross-sectional study to estimate the expressed loss of utility in the Spanish population
- Correction: Prevalence of damaged and missing teeth among women in the southern plains of Nepal: Findings of a simplified assessment tool
- Correction: Tissue-Specific Expressed Antibody Variable Gene Repertoires
- Retraction: Immunoglobulin G Expression in Lung Cancer and Its Effects on Metastasis
- Correction: Causal knowledge promotes behavioral self-regulation: An example using climate change dynamics
- Retraction: Use of Granulocyte Colony-Stimulating Factor for the Treatment of Thin Endometrium in Experimental Rats
- Correction: Dynamic mechanical and nanofibrous topological combinatory cues designed for periodontal ligament engineering
- Correction: Evaluating the foundations that help avert antimicrobial resistance: Performance of essential water sanitation and hygiene functions in hospitals and requirements for action in Kenya
- From seed to flour: Sowing sustainability in the use of cantaloupe melon residue (Cucumis melo L. var. reticulatus)
- Core Scientific Dataset Model: A lightweight and portable model and file format for multi-dimensional scientific data
- Accounting for measurement error to assess the effect of air pollution on omic signals
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- Barriers for tuberculosis case finding in Southwest Ethiopia: A qualitative study
- Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia
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- Two angles of overqualification-the deviant behavior and creative performance: The role of career and survival job
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- Learning efficient haptic shape exploration with a rigid tactile sensor array
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- Severe thiamine deficiency in eastern Baltic cod (Gadus morhua)
- Transfer entropy as a variable selection methodology of cryptocurrencies in the framework of a high dimensional predictive model
- Psychometric validation of Czech version of the Sport Motivation Scale
- Correction: Multiple innate antibacterial immune defense elements are correlated in diverse ungulate species
- Recognition of personality disorder and anxiety disorder comorbidity in patients treated for depression in secondary psychiatric care
- Correction: Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform
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