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Evaluating poverty alleviation strategies in a developing country
Authors: Pramod K. Singh aff001; Harpalsinh Chudasama aff001
Authors place of work: Institute of Rural Management Anand (IRMA), Anand, Gujarat, India aff001
Published in the journal: PLoS ONE 15(1)
Category: Research Article
doi: https://doi.org/10.1371/journal.pone.0227176Summary
A slew of participatory and community-demand-driven approaches have emerged in order to address the multi-dimensional nature of poverty in developing nations. The present study identifies critical factors responsible for poverty alleviation in India with the aid of fuzzy cognitive maps (FCMs) deployed for showcasing causal reasoning. It is through FCM-based simulations that the study evaluates the efficacy of existing poverty alleviation approaches, including community organisation based micro-financing, capability and social security, market-based and good governance. Our findings confirm, to some degree, the complementarity of various approaches to poverty alleviation that need to be implemented simultaneously for a comprehensive poverty alleviation drive. FCM-based simulations underscore the need for applying an integrated and multi-dimensional approach incorporating elements of various approaches for eradicating poverty, which happens to be a multi-dimensional phenomenon. Besides, the study offers policy implications for the design, management, and implementation of poverty eradication programmes. On the methodological front, the study enriches FCM literature in the areas of knowledge capture, sample adequacy, and robustness of the dynamic system model.
Keywords:
Finance – Health care policy – Cognition – Social cognition – Centrality – Welfare (social security) – economic growth – Economics of poverty
1. Introduction
1.1. Poverty alleviation strategies
Although poverty is a multi-dimensional phenomenon, poverty levels are often measured using economic dimensions based on income and consumption [1]. Amartya Sen’s capability deprivation approach for poverty measurement, on the other hand, defines poverty as not merely a matter of actual income but an inability to acquire certain minimum capabilities [2]. Contemplating this dissimilarity between individuals’ incomes and their inabilities is significant since the conversion of actual incomes into actual capabilities differs with social settings and individual beliefs [2–4]. The United Nations Development Programme (UNDP) also emphasises the capabilities’ approach for poverty measurement as propounded by Amartya Sen [5]. “Ending poverty in all its forms everywhere” is the first of the 17 sustainable development goals set by the United Nations with a pledge that no one will be left behind [6]. Development projects and poverty alleviation programmes all over the world are predominantly aimed at reducing poverty of the poor and vulnerable communities through various participatory and community-demand-driven approaches [7,8]. Economic growth is one of the principal instruments for poverty alleviation and for pulling the poor out of poverty through productive employment [9,10]. Studies from Africa, Brazil, China, Costa Rica, and Indonesia show that rapid economic growth lifted a significant number of poor people out of financial poverty between 1970 and 2000 [11]. According to Bhagwati and Panagariya, economic growth generates revenues required for expanding poverty alleviation programmes while enabling governments to spend on the basic necessities of the poor including healthcare, education, and housing [9]. Poverty alleviation strategies may be categorised into four types including community organisations based micro-financing, capability and social security, market-based, and good governance.
Micro-finance, aimed at lifting the poor out of poverty, is a predominant poverty alleviation strategy. Having spread rapidly and widely over the last few decades, it is currently operational across several developing countries in Africa, Asia, and Latin America [12–21]. Many researchers and policy-makers believe that access to micro-finance in developing countries empowers the poor (especially women) while supporting income-generating activities, encouraging the entrepreneurial spirit, and reducing vulnerability [15, 21–25]. There are fewer studies, however, that show conclusive and definite evidence regarding improvements in health, nutrition, and education attributable to micro-finance [21,22]. For micro-finance to be more effective, services like skill development training, technological support, and strategies related to better education, health and sanitation, including livelihood enhancement measures need to be included [13,17,19].
Economic growth and micro-finance for the poor might throw some light on the financial aspects of poverty, yet they do not reflect its cultural, social, and psychological dimensions [11,21,26]. Although economic growth is vital for enhancing the living conditions of the poor, it does not necessarily help the poor exclusively tilting in favour of the non-poor and privileged sections of society [4]. Amartya Sen cites social exclusion and capability deprivation as reasons for poverty [4,27]. His capabilities’ approach is intended to enhance people’s well-being and freedom of choices [4,27]. According to Sen, development should focus on maximising the individual’s ability to ensure more freedom of choices [27,28]. The capabilities approach provides a framework for the evaluation and assessment of several aspects of the individual’s well-being and social arrangements. It highlights the difference between means and ends as well as between substantive freedoms and outcomes. An example being the difference between fasting and starving [27–29]. Improving capabilities of the poor is critical for improving their living conditions [4,10]. Improving individuals’ capabilities also helps in the pooling of resources while allowing the poor to engage in activities that benefit them economically [4,30]. Social inclusion of vulnerable communities through the removal of social barriers is as significant as financial inclusion in poverty reduction strategies [31,32]. Social security is a set of public actions designed to reduce levels of vulnerability, risk, and deprivation [11]. It is an important instrument for addressing the issues of inequality and vulnerability [32]. It also induces gender parity owing to the equal sovereignty enjoyed by both men and women in the context of economic, social, and political activities [33].
The World Development Report 1990 endorsed a poverty alleviation strategy that combines enhanced economic growth with provisions of essential social services directed towards the poor while creating financial and social safety nets [34,35]. Numerous social safety net programmes and public spending on social protection, including social insurance schemes and social assistance payments, continue to act as tools of poverty alleviation in many of the developing countries across the world [35–39]. These social safety nets and protection programmes show positive impacts on the reduction of poverty, extent, vulnerability, and on a wide range of social inequalities in developing countries. One major concern dogging these programmes, however, is their long-term sustainability [35].
Agriculture and allied farm activities have been the focus of poverty alleviation strategies in rural areas. Lately, though, much of the focus has shifted to livelihood diversification on the part of researchers and policy-makers [15,40]. Promoting non-farm livelihoods, along with farm activities, can offer pathways for economic growth and poverty alleviation in developing countries the world over [40–44]. During the early 2000s, the development of comprehensive value chains and market systems emerged as viable alternatives for poverty alleviation in developing countries [45]. Multi-sectoral micro-enterprises may be deployed for enhancing productivity and profitability through value chains and market systems, they being important for income generation of the rural poor while playing a vital role in inclusive poverty eradication in developing countries [46–48].
Good governance relevant to poverty alleviation has gained top priority in development agendas over the past few decades [49,50]. Being potentially weak in the political and administrative areas of governance, developing countries have to deal with enormous challenges related to social services and security [49,51]. In order to receive financial aid from multinational donor agencies, a good governance approach towards poverty reduction has become a prerequisite for developing countries [49,50]. This calls for strengthening a participatory, transparent, and accountable form of governance if poverty has to be reduced while improving the lives of the poor and vulnerable [50,51]. Despite the importance of this subject, very few studies have explored the direct relationship between good governance and poverty alleviation [50,52,53]. Besides, evidence is available, both in India and other developing countries, of information and communication technology (ICT) contributing to poverty alleviation programmes [54]. Capturing, storing, processing, and transmitting various types of information with the help of ICT empowers the rural poor by increasing access to micro-finance, expanding the use of basic and advance government services, enabling the development of additional livelihood assets, and facilitating pro-poor market development [54–56].
1.2. Proposed contribution of the paper
Several poverty alleviation programmes around the world affirm that socio-political inclusion of the poor and vulnerable, improvement of social security, and livelihood enhancement coupled with activities including promoting opportunities for socio-economic growth, facilitating gender empowerment, improving facilities for better healthcare and education, and stepping up vulnerability reduction are central to reducing the overall poverty of poor and vulnerable communities [1,11]. These poverty alleviation programmes remain instruments of choice for policy-makers and development agencies even as they showcase mixed achievements in different countries and localities attributable to various economic and socio-cultural characteristics, among other things. Several poverty alleviation programmes continue to perform poorly despite significant investments [8]. The failure rate of the World Bank’s development projects was above 50% in Africa until 2000 [57]. Hence, identifying context-specific factors critical to the success of poverty alleviation programmes is vital.
Rich literature is available pertinent to the conceptual aspects of poverty alleviation. Extant literature emphasises the importance of enhancing capabilities and providing social safety, arranging high-quality community organisation based micro-financing, working on economic development, and ensuring good governance. However, the literature is scanty with regard to comparative performances of the above approaches. The paper tries to fill this gap. This study, through fuzzy cognitive mapping (FCM)-based simulations, evaluates the efficacy of these approaches while calling for an integrative approach involving actions on all dimensions to eradicate the multi-dimensional nature of poverty. Besides, the paper aims to make a two-fold contribution to the FCM literature: i) knowledge capture and sample adequacy, and ii) robustness of the dynamic system model.
The remainder of the paper proceeds as follows: We describe the methodology adopted in the study in section two. Section three illustrates key features of the FCM system in the context of poverty alleviation, FCM-based causal linkages, and policy scenarios for poverty alleviation with the aid of FCM-based simulations. We present our contribution to the extant literature relating to FCM and poverty alleviation. Finally, we conclude the paper and offer policy implications of the study.
2. Methodology
We conducted the study with the aid of the FCM-based approach introduced by Kosko in 1986 [58]. The process of data capture in the FCM approach is considered quasi-quantitative because the quantification of concepts and links may be interpreted in relative terms [59] allowing participants to debate the cause-effect relations between the qualitative concepts while generating quantitative data based on their experiences, knowledge, and perceptions of inter-relationships between concepts [60–64,65–68]. The FCM approach helps us visualise how interconnected factors/ variables/ concepts affect one another while representing self-loop and feedback within complex systems [62,63,69]. A cognitive map is a signed digraph with a series of feedback comprising concepts (nodes) that describe system behavior and links (edges) representing causal relationships between concepts [60–63,65,70–72]. FCMs may be created by individuals as well as by groups [60,72,73]. Individual cognitive mapping and group meeting approaches have their advantages and drawbacks [72]. FCMs allow the analysis of non-linear systems with causal relations, while their recurrent neural network behaviour [69,70,74] help in modelling complex and hard-to-model systems [61–63]. The FCM approach also provides the means to build multiple scenarios through system-based modelling [60–64,69,74,75].
The strengths and applications of FCM methodology, focussing on mental models, vary in terms of approach. It is important to remember, though, that (i) the FCM approach is not driven by data unavailability but is responsible for generating data [60,76]. Also that (ii) FCMs can model complex and ambiguous systems revealing hidden and important feedback within the systems [58,60,62,69,76] and (iii) FCMs have the ability to represent, integrate, and compare data–an example being expert opinion vis-à-vis indigenous knowledge–from multiple sources while divulging divergent viewpoints [60]. (iv) Finally, FCMs enable various policy simulations through an interactive scenario analysis [60,62,69,76].
The FCM methodology does have its share of weaknesses. To begin with: (i) Respondents’ misconceptions and biases tend to get encoded in the maps [60,62]. (ii) Possibility of susceptibility to group power dynamics in a group model-building setting cannot be ruled out; (iii) FCMs require a large amount of post-processing time [67]. (iv) The FCM-based simulations are non-real value and relative parameter estimates and lack spatial and temporal representation [60,77,78].
These drawbacks notwithstanding, we, along with many researchers, conceded that the strengths and applications of FCM methodology outweighed the former, particularly with regard to integrating data from multiple stakeholders with different viewpoints.
We adopted the multi-step FCM methodology discussed in the following sub-sections. We adopted the multi-step FCM methodology discussed in the following sub-sections. We obtained individual cognitive maps from the participants in two stages: ‘open-concept design’ approach followed by the ‘pre-concept design’ approach. We coded individual cognitive maps into adjacency matrices and aggregated individual cognitive maps to form a social cognitive map. FCM-based simulation was used to build policy scenarios for poverty alleviation using different input vectors.
2.1. Obtaining cognitive maps from the participants
A major proportion of the literature on fuzzy cognitive maps reflects an ‘open-concept design’ approach, while some studies also rely on a ‘pre-designed concept’ approach with regard to data collection.
In the case of the ‘open-concept design’ approach, concepts are determined entirely by participants and are unrestricted [59,60,62,63,65–67,79,80]. While the researcher determines the context of the model by specifying the system being modelled, including the boundaries of the system, participants are allowed to decide what concepts will be included. This approach provides very little restriction in the knowledge capture from participants and can be extremely beneficial especially if there is insufficient knowledge regarding the system being modelled.
In the case of the ‘pre-designed concept’ approach, concepts are pre-determined either by experts or by researchers using available literature [64,69,74,81,82]. In this approach, the researcher is able to exercise a higher degree of control over how the system is defined. The ‘pre-designed concept’ approach is likely to be more efficient compared to the ‘open-concept design’ in the context of time required for model building. However, it restricts the diversity of knowledge captured from participants and is able to influence more heavily the way in which this knowledge is contextualised based on input and interpretation.
We have adopted a ‘mixed-concept design’ approach for this study involving data collection in two stages:
2.1.1. Stage one: ‘Open-concept design’ approach
During the first stage, we engaged with the experts and national-level policy-makers who designed the Deendayal Antyodaya Yojana-National Rural Livelihoods Mission (DAY-NRLM), a centrally sponsored programme in India. The DAY-NRLM aims at abolishing rural poverty by promoting multiple livelihoods for the rural poor and vulnerable households. The programme is focussed on organising the rural poor and vulnerable communities into self-help groups (SHGs) while equipping them with means of self-employment. The four critical components of the programme viz., (i) universal social mobilisation and institution building, (ii) financial inclusion, (iii) convergence and social development, and (iv) livelihood enhancement are designed to address the exclusions of these communities, eliminate their poverty, and bring them within the ambit of mainstream economic and social systems. Participants comprising three experts from the World Bank, nine experts from the National Mission Management Unit of the DAY-NRLM, and 25 monitoring and evaluation experts from 25 states of India created 37 FCMs. A sample map of FCMs obtained from these participants is provided in S1 Fig. We demonstrated the construction of fuzzy cognitive maps with the aid of a map from a neutral problem domain referring to direct and consequential impacts of deforestation, which had been approved by the ‘Research Ethics Committee’ of our Institute.
A group discussion was held with the participants regarding the issues under investigation subsumed under the title “critical factors required to ensure that people come out of poverty on a sustainable basis”. It prompted them to identify major concepts pertaining to the above. These were listed down on a whiteboard by the researchers. Once the participants had understood the process of drawing a fuzzy cognitive map and identified major concepts responsible for poverty alleviation, they were asked to draw a fuzzy cognitive map individually. The participants used the concepts listed on the whiteboard to draw fuzzy cognitive maps. Many participants added new concepts while drawing the maps. They then connected all the concepts through various links based on their personal understanding. The links, represented by arrows in between concepts, show the direction of influence between them.
The participants assigned weights to each link on a scale of 1–10 to describe the relationship strength between two concepts [60]. Ten denoted the highest strength and one the lowest; the numbers 1–3 signified relationships with low strength, 4–6 signified relationships with medium strength, and 7–10 signified relationships with high strength. After constructing the FCMs each participant made a presentation, which was video-recorded, explaining their map to the researchers. The researchers, based on causal relationships between the concepts, assigned positive and negative polarities to the weights of the links [59,60,62–64,66–68,72].
2.1.2. Stage two: ‘Pre-designed concept’ approach
During the second stage, an instrument depicting 95 concepts under 22 concept categories was prepared based on the FCMs obtained from participants during the first stage (S2 Fig). The instrument also contained links between the 22 concept categories. ‘Research Ethics Committee’ of our Institute approved this instrument as well. We used this instrument during the second stage to obtain FCMs. We obtained 123 additional FCMs, of which 20 FCMs were obtained from the Chief Executive Officers along with experts from livelihood, enterprise, and community development domains belonging to the National Mission Management Unit in the states of Bihar, Jharkhand, Madhya Pradesh, and Maharashtra. The remaining 103 FCMs were obtained from 103 district project coordinators, who had agreed to participate in the study. Unlike most FCM-based studies, which usually rely upon 30 to 50 participants, this study involved 174 experts and project implementers. Most participants produced FCMs individually and some in pairs. The 174 participants produced 160 FCMs.
The participants were given the instrument and were instructed to assign weights to each concept, wherever applicable, and leave other cells blank. These weights were assigned based on the concepts’ significance regarding poverty alleviation in India. The instrument was designed to allow participants to add new concepts and/or remove existing ones from the instrument based on their understanding and perceptions. Later, the participants were asked to assign weights to all pre-established links between the 22 concept categories. The instrument also allowed participants to draw new linkages between the categories and/or discard the existing relationships based on their understanding and perceptions. After constructing the FCMs each participant made a presentation to the researchers, which was video-recorded. During the process, participants added 55 new concepts within the pre-classified 22 concept categories. Five new concepts were added under a new category. The final data comprised 23 concept categories and 155 concepts (S3 Fig).
2.2. Coding individual cognitive maps into adjacency matrices
The individual FCMs were coded into separate excel sheets, with concepts listed in vertical and horizontal axes, forming an N x N adjacency matrix. The weights of the links, on a scale of 1−10, were normalised in the −1 to +1 range [62,63]. The values were then coded into a square adjacency matrix whenever a connection existed between any two concepts [60,62–64,66].
2.3. Aggregation of individual cognitive maps
There are various methods of aggregating individual FCMs; each method has advantages and disadvantages [83]. We aggregated individual adjacency matrices obtained by normalising each adjacency matrix element according to its decisional weight, wi, and the number of participants, k, who supported it. The following equation illustrates the augmentation of individual adjacency matrices:
MFCM is the aggregated adjacency matrix, where, k represents the number of participants interviewed; wi is the decisional weight of the expert i, where, ∑i=1kwi=1; and mi is the adjacency matrix written by the participant i.
This aggregation approach has been adopted by many researchers [59,60,63–67,74,79,84–87]. A large number of concepts in an aggregated (social/ group) fuzzy cognitive map with many interconnections and feedback form a complex system. Aggregation of all the 160 individual cognitive maps produced a social cognitive map (S1 Table). This shows the cumulative strength of the system.
2.4. Structural analysis of the system
Structural analysis of the final condensed social cognitive map was undertaken using the FCMapper software. The graph theory of a cognitive map provides a way of characterising FCM structures employing several indices in addition to the number of concepts (C) and links (W) such as in-degree, out-degree, centrality, complexity index, and density index [60].
The in-degree is the column sum of absolute values of a concept in the adjacency matrix. It shows the cumulative strength of links entering the concept (wji). Where n = the total number of concepts:
The out-degree is the row sum of absolute values of a concept in the adjacency matrix. It shows the cumulative strengths of links exiting the concept (wij). Where n = the total number of concepts:
The degree centrality of a concept is the summation of its in-degree and out-degree. The higher the value, the greater is the importance of a concept in the overall model [60].
Transmitter concepts (T) depict positive out-degree and zero in-degree. Receiver concepts (R) represent positive in-degree and zero out-degree. Ordinary concepts (O) have both a non-zero in-degree and out-degree [60].
The complexity index of a cognitive map is the ratio of receiver concepts (R) to transmitter concepts (T). Higher complexity indicates more complex systems thinking [60]:
The density index of a cognitive map is an index of connectivity showing how connected or sparse the maps are. It is a product of the number of concepts (C) and the number of links (W). Here the number of existing links is compared to the number of all possible links. Higher the density, greater the existence of potential management policies [60]:
2.5. Fuzzy cognitive maps-based simulations
The scenarios formed through FCM-based simulations can serve to guide managers and policy-makers during the decision-making process [62–64,66,69,82,88–90]. An FCM is formed out of the adjacency matrix and a state vector, representing the values of the connections between the concepts and the values of the system concepts [62,63,69]. The weighted adjacency matrix of an FCM forms a recurrent neural network, including concepts and interconnections for processing the information and feedback loops [88,91]. These have been used to analyse system behavior by running FCM-based simulations in order to determine possible future scenarios.
In order to understand FCM-based simulations, let us understand the FCM as a quadruple, i.e. M = (Cn, W, A, f), where, n is the set of all concepts (C) in the map, W: (Ci, Cj) → wij is a function which defines the causal weight matrix, WM×M, A: (Ci) → A(t)i is a function that computes the activation degree of each concept Ci at the discrete-time step t (t = 1, 2, …, T), and f (.) is the transfer function [63,71,92,93]. Knowledge and experience of stakeholders regarding the system determine the type and number of concepts as well as the weights of the links in FCMs. The value Ai of a concept Ci, expresses the quantity of its corresponding value. With values assigned to the concepts and weights, the FCM converges to an equilibrium point [71,91]. At each step, the value Ai of a concept is calculated, following an activation rule, which computes the influence of other concepts to a specific concept.
We have used an increasingly popular activation rule [61–64,90,91] introduced by Stylios [94], which is as follows:
Where, n is the total number of concepts, Ai(t+1) is the value of concept Ci at simulation step t +1, Ai(t) is the value of concept Ci at simulation step t, Aj(t) is the value of concept Cj at simulation step t, wji is the weight of the interconnection between concept Cj and concept Ci, and f is the transformation function [64,90]. The restriction i ≠ j is used when self-causation is assumed to be impossible [91].
The simulation outcomes also depend on the type of transformation function used. The most frequently used transformation functions (ƒ) are sigmoid and hyperbolic tangent functions [90–93]. When the values of concepts can only be positive, i.e. in the range of (0,1), the most common unipolar sigmoid transformation function is used [64,91–93]. Following is the mathematical equation of the sigmoid transformation function:
Where, ? is a real positive number (? > 0) and a constant value that determines the slope steepness factor, while, x is the value of concept Ai(t) on the equilibrium point [64,93]. Higher values of ? increase the steepness and make it more sensitive to the changes of x. Hence, the derivative δfδx becomes higher when increasing the activation value [95].
2.5.1. Development of input vectors for policy scenarios
Identifying pivotal concepts is a traditional approach in scenario planning that helps linking storylines to the quantitative model [96]. In the FCM-based scenario analysis, recognition of such pivotal concepts, termed as input vectors, mainly relies upon participants’ perceptions along with the characteristics of the model. We identified four input vectors for four poverty alleviation policy scenarios based on existing literature on poverty alleviation strategies. The fifth input vector is based on the concepts with the highest weights identified by the participants. In the sixth input vector, the concept representing entrepreneurship is replaced by the concept representing livelihood diversification considering its importance based on existing literature [15,40]. All six scenarios are explained below:
Scenario 1: High-quality community organisation based micro-financing—Input vector 1: C2, C3, C4, C5, C11, and C12 (strong institutions of the poor, community heroes driving the programme, capacity building of the community organisations, mainstream financial institutions supporting community organisations, need-based finance, and developing repayment culture). This scenario tries to examine how high-quality community organisation based micro-finance could alleviate poverty.
Scenario 2: Capabilities and social security—Input vector 2: C19, C20, C21, C22, and C23 (affordable and approachable education and healthcare, social inclusion, building personal assets, adequate knowledge base, and vulnerability reduction). This scenario tries to estimate how improving the capabilities of the poor and providing them social security would help alleviate poverty.
Scenario 3: Market-based approach—Input vector 3: C13, C14, C15, C16, and C17 (livelihood diversification, entrepreneurship, multi-sectoral collective enterprise, value addition by collectives, and market linkages). This scenario tries to evaluate how a market-based approach could alleviate poverty.
Scenario 4: Good governance approach—Input vector 4: C6, C7, C8, C9, and C10 (good governance systems and processes, robust monitoring mechanisms, implementation process, linkages/ convergence/ partnerships, and enabling policy & political will). This scenario tries to evaluate how good governance is crucial for poverty alleviation.
Scenario 5: Integrative approach 1—Input vector 5: C2, C3, C6, C9, C10, C14, and C19 (strong institutions of the poor, community heroes driving the programme, sound governance systems and processes, enabling policy & political will, linkages/ convergence/ partnerships, entrepreneurship, and affordable and approachable education and healthcare). This scenario tries to assess how the most critical concepts, identified by the participants, are crucial for poverty alleviation.
Scenario 6: Integrative approach 2—Input vector 6: C2, C3, C6, C9, C10, C13, and C19 (strong institutions of the poor, community heroes driving the programme, good governance systems and processes, enabling policy & political will, linkages/ convergence/ partnerships, livelihood diversification, and affordable and approachable education and healthcare). This scenario tries to assess how the most important concepts, including livelihood diversification, are critical for the alleviation of poverty. Based on the relative weights, scenarios 4 to 6 also had alternative input vectors incorporating sensitive support structure (C1) without any demonstrable results.
2.5.2. Simulation process
Each concept in the system has an initial state vector A0 that varies from 0 to |1|. which is associated with an activation vector, where 0 means ‘non-activated’ and |1| means ‘activated’ [65,80]. A new state of the concepts can be calculated by multiplying the adjacency matrix with the state vector [69]. When one or more concepts are ‘activated’ this activation spreads through the matrix following the weighted relationships. During the simulation process, each iteration produces a new state vector with ‘activated’ concepts and ‘non-activated’ concepts. Self-loops and feedback cause a repeated activation of concepts, introducing non-linearity to the model [61,70,88]. The activation of concepts is iterated, using a ‘squashing function’ to rescale concept values towards |1|, until the vector values stabilise and the model reaches equilibrium or steady-state [61,65,70]. The resulting concept values may be used to interpret outcomes of a particular scenario and to study the dynamics of the modeled system [61–63,70].
The simulation process is carried out with the initial state vector of the input vectors, identified in each scenario (1 to 6), clamped to 1 (A1) and the initial state vector of all the other concepts clamped to 0 (A0). We applied the activation rule proposed by Stylios [94], to run simulations because of its memory capabilities along with the sigmoid transformation function as the links have only positive values. The sensitivity of the system was analysed by clamping the concepts of each input vector to 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, and 0.9 (S4 Fig) to determine whether the system behaves in a similar manner in each simulation [62,63,72,89].
3. Results and discussions
3.1. Key features of the FCM system in the context of poverty alleviation
The social cognitive map built by combining the individual FCMs comprises 23 concepts and 51 links (Fig 2 and S1 Table). This FCM system has a density index of 0.088, which signifies that 8.8% links are actually made of the maximum number of links that could theoretically exist between the 24 concepts. The FCM system has a complexity index of 0.125, which showcases more utility outcomes and less controlling forcing functions. However, unless the density and complexity values of the FCM system are compared to those of other FCM systems representing a similar topic, interpretation of these figures is challenging [75].
There are some autonomous concepts virtually disengaged from the system. Some dependent concepts although have a relatively low degree of influence, exhibit strong dependence. The contribution of a concept in a cognitive map can be understood by its degree centrality, which is the summation of in-degree and out-degree. Table 1 illustrates the in-degree and out-degree and degree centrality of the FCM system. Concepts have been depicted such as C2: strong institutions of the poor, C15: multi-sectoral collective enterprise development, C13: livelihood diversification and C14: entrepreneurship have higher degree centrality. These concepts should be interpreted as the greatest strength of poverty alleviation strategies. The most influential concepts (i.e., those with the highest out-degree) affecting the poverty alleviation strategies are C6: good governance systems and processes, C19: affordable and approachable education and healthcare, C18: climate-smart production systems, C2: strong institutions of the poor, and C5: mainstream financial institutions supporting CBOs. Scenario analysis results will later help us gain a deeper understanding of the connectivity and influencing concepts of poverty alleviation.
Tab. 1. The structural analysis of the FCM system. The participants also provided the state vector values (A) of all the concepts (C) based on their understanding of the relative significance of these concepts regarding poverty alleviation in India (Fig 1).
Fig. 1. The relative importance of the concepts as perceived by the stakeholders. The results show that participants assigned greater significance to the following concepts - C3: community heroes driving the programme, C1: quality support structure, C19: affordable and approachable education and healthcare, C6: good governance systems and processes, C2: strong institutions of the poor, C12: developing repayment culture, and C7: robust monitoring mechanisms.
The results acknowledge that building strong institutions of the poor for a community-demand-driven and community-managed poverty alleviation programme is likely to enjoy greater success. They also confirm that developing robust monitoring mechanisms can ensure better functioning of the community-based organisations (CBOs). Robust governance systems and processes are essential for vibrant CBOs. They can empower communities to have better access to affordable education and healthcare facilities. Better access to micro-finance for these CBOs could help alleviate the economic poverty of the poor and vulnerable communities.
The results, however, fail to capture the cultural and social dimensions of poverty.
3.2. Understanding the poverty alleviation strategy
This section summarises the views of participants across the concepts based on the presentations made by them to the researcher during both the stages of knowledge capture. Fig 2 illustrates the cognitive interpretive diagram formed using the social cognitive map. The concepts, represented by each node in the diagram, are connected by several links. These links establish relationships between the concepts representing the basis of degree centrality. The central concept is people coming out of poverty, which is depicted with yellow color in Fig 2.
Participants indicated that setting up a quality and dedicated support structures at multiple levels (national, state, district, and block) is essential for poverty alleviation (Fig 2: C1). The support structures should be staffed with professionally competent and dedicated human resources. The crucial role of these support structures is to build and nurture strong institutions of the poor (Fig 2: C2) at multiple levels and evanesce when community heroes start driving the programme. Building and sustaining strong, inclusive, self-managed, and self-reliant institutions of the poor at various levels such as self-help groups (SHGs), village organisations (VOs), and cluster-level federations (CLFs) through training, handholding, and systematic guidance are crucial to the success of a poverty alleviation programme. However, superior CBOs are required to ensure the quality of primary-level institutions and their sustainability. Adherence to the five principles (regular meetings, regular savings, regular inter-loaning, timely repayment of the loans, and up-to-date books of accounts), co-ordination, and cohesiveness between the members would go a long way in building strong institutions of the poor.
Fig. 2. A social cognitive map showing the critical factors required for poverty alleviation. Participants emphasised the importance of community heroes in driving the poverty alleviation programme (Fig 2: C3). The poverty eradication programme is likely to meet with greater success if it is entirely operated and managed by the community. Involving experienced community members for social mobilisation, capacity building and scaling-up of various processes within the project will ensure effective functioning and implementation of the programme. Participants believed that the capacity building of the CBOs, community resource persons, community cadres, and community service providers (Fig 2: C4) are essential for poverty alleviation. Apart from training in social and financial inclusion, these community members should be provided with knowledge, skills, and tools to improve their existing livelihoods and for managing innovative livelihood collectives and micro-enterprises. Providing access to financial services to society’s most vulnerable group in a cost-effective manner through mainstream financial institutions and allowing the poor to become preferred clients of the banking system is fundamental to the financial inclusion strategy of a poverty alleviation programme (Fig 2: C5). The SHG-bank linkage enables an easy access to micro-finance for the SHGs. It also serves to foster their faith towards the banking system.
Good governance systems and processes are crucial to building sensitive support structures and strong institutions of the poor (Fig 2: C6). A well-structured process for participatory identification of the poor by the community helps identify very poor, poor, vulnerable, tribal, differently-abled, and other marginalised communities in a village. A robust process for grading the quality of SHGs and their federations could help maintain a high standard for these institutions. Strong, robust, and transparent monitoring mechanisms (Fig 2: C7) could ensure good governance systems and processes. The process-oriented approach of the programme needs to undergo continuous review, assessment, and course-correction from the qualitative and quantitative progress achieved at various levels. Hence, participants suggested that a robust ICT-based monitoring and evaluation system remain in place for facilitating informed decision-making at all levels. The participants also indicated the urgency of robust implementation of institutional accountability and a self-monitoring process in institutions of the poor at all levels, including peer internal review mechanisms, external social auditing, public expenditure tracking, and community scorecards, in order to build stronger institutions of the poor (Fig 2: C8). Transparency in the functioning of human resources at all levels aided by regular meetings, reviews, and monitoring of progress could ensure effective implementation of the programme. Maintaining equity and transparency in releasing finances and ensuring effective fund utilisation across all eligible groups could also help focus on the most vulnerable groups.
The participants believed that a poverty alleviation programme should have a strong convergence with other welfare programmes (Fig 2: C9). Stronger emphasis should be placed on convergence for developing synergies directly and through the institutions of the poor. Participants suggested that the programme recognise the importance of engaging with industries to set up platforms for public-private-partnerships in farm and non-farm sectors while developing various sector-specific value chains to harness the comparative advantage of the micro-enterprise sector. The political will to support and encourage CBOs, enabling policies for smooth and efficient working of the institutions of the poor, diminished political influence in the decision-making of CBOs, and timely and adequate resource allocation on the part of government institutions is critical for poverty alleviation programmes (Fig 2: C10).
Participants acknowledged that livelihood augmentation requires customised need-based financing for the poor and vulnerable (Fig 2: C11). Access to micro-finance at affordable rates of interest coupled with desired amounts and convenient repayment terms are needed for the poverty reduction of communities. Providing interest subvention for all SHG loans availed from mainstream financial institutions, based on prompt loan repayment, helps develop a healthy loan repayment culture (Fig 2: C12).
Participants opined that diversification of livelihoods would ensure steady incomes for households (Fig 2: C13). The development of micro-enterprise in farm and non-farm sectors could encourage institutions of the poor in the aggregation of produce, value-addition, and marketing of finished goods. Therefore, it is imperative that more and more sustainable enterprises be created by the poor to improve their livelihood security. The demand-driven entrepreneurship (Fig 2: C14) programmes could be taken up through public-private-partnerships. Provisions could be made for incubation funds and start-up funds for the development of multi-sectoral livelihood collectives (Fig 2: C15) to foster a collective entrepreneurship spirit. Livelihood activities, in order to be commercially viable, would require economy of scale, enabling the adoption of available technologies while providing better bargaining power, offering a more significant political clout, and influencing public policy over time. Building specialised multi-sectoral collective institutions of the poor, such as producers’ companies and co-operatives could make the latter key players in the market. These livelihood institutions could carry out participatory livelihood mapping and integrated livelihood planning as well as build robust livelihood clusters, supply chains, and value chains. They could also identify gaps in the supply and value chains, create backward and forward linkages, and tap market opportunities for intervention and collectivisation for chosen livelihood activities (Fig 2: C16; C17). Developing adequate and productive infrastructure for processing, storage, packaging, and transportation is crucial for value addition (Fig 2: C16). The demand-based value chain development is currently evident in micro-investment planning processes. Identifying non-farm activities to support enterprises in a comprehensive way could also be crucial. Adequate market linkages and support services like branding, market research, market knowledge, market infrastructure, and backward linkages would go a long way in deriving optimum returns from the chosen livelihood activities (Fig 2: C17).
Several eco-friendly, climate-smart, and innovative approaches in agriculture production systems will ensure the sustainability of production systems even in the context of climate change (Fig 2: C18). Contemporary grassroots innovations supplemented by robust scientific analysis, mainly supported by various government programmes, are likely to ensure enhanced and efficient production systems. Focus on developing adequate infrastructure for processing, storing, and transporting for value addition would serve to reduce post-harvest losses.
Participants believed that affordable and approachable quality education up to the secondary level as well as affordable and quality healthcare facilities are crucial for poverty alleviation (Fig 2: C19). Convergence with mid-day-meal schemes will not only encourage communities to send their children to schools but also help curb malnutrition. An affordable and approachable healthcare system is likely to help reduce health-related vulnerabilities of the poor. Crucial is an approach that identifies all needy and poor households while primarily focussing on vulnerable sections like scheduled castes, scheduled tribes, particularly vulnerable tribal groups, single women and women-headed households, disabled, landless, migrant labor, isolated communities, and those living in disturbed areas. Equally crucial is including them in institutions of the poor (Fig 2: C20). Customised micro-financing coupled with adequate instruments on healthcare and education could aid vulnerability reduction (Fig 2: C23). The social, human, and personal assets created by developing institutions of the poor are crucial for sustaining and scaling-up of the poverty alleviation programme (Fig 2: C21). This will also allow women to articulate their problems and improve their self-confidence, enhance their respect in society, develop leadership qualities, inspire them to speak and express their feelings unhesitatingly, and empower them economically and socially. Developing an academic understanding of the factors that support community institutions is crucial for the social infrastructure developed to facilitate the social capital building of the poor and vulnerable communities (Fig 2: C22).
3.3. FCM-based simulations
In order to evaluate critical factors responsible for poverty alleviation, we used six input vectors for FCM-based simulations. For each scenario, causal propagation occurs in each iteration until the FCM system converges [62–65,67,70,91]. This happens when no change takes place in the values of a concept after a certain point, also known as the system steady-state; the conceptual vector at that point is called the final state vector [62–65,67,70,91]. Values of the final state vectors depend on the structure of the FCM system and concepts considered for input vectors. The larger the value of the final state vectors, the better the selected policies [62–65]. Comparisons between the final state vectors of the alternative simulations are drawn in order to assess the extent of the desired transition by activating each set of input vectors. The initial values and final state vectors of all the concepts for every scenario are presented in Table 2. The graphical representation of various scenarios for poverty alleviation is provided in the S5 Fig.
Tab. 2. Initial and final values of all the concepts for every FCM-based scenarios. The first scenario highlights the effects of high-quality community organisations based micro-financing approach. If strong institutions of the poor are built and community heroes start driving the poverty alleviation programme, capacity building of the CBOs gets underway. If mainstream financial institutions start supporting CBOs while customised need-based finance and a repayment culture is developed significant efforts would still be required for putting good governance systems and processes in place along with linkages/ convergences/ partnerships along with other schemes while building capabilities of the poor. In the case of successful micro-financing, there will be opportunities for livelihood diversification, entrepreneurship, multi-sectoral collective enterprise development, value addition by collectives, and market linkages.
The second scenario highlights the effects of the capabilities approach and social security. In this case, affordable and approachable education and healthcare, social inclusion, the building of personal assets, adequate knowledge base, and vulnerability reduction are ensured. In this context, ample efforts will be required for mainstream financial institutions supporting CBOs, good governance systems and processes, and linkages/ convergences/ partnerships with other schemes. Efforts will also be required for a quality support structure and customised need-based finance. The capability and social security enhancement could have prospects for strong institutions of the poor, better implementation processes, livelihood diversification, entrepreneurship, value addition by collectives, multi-sectoral collective enterprise development, and vulnerability reduction.
The third scenario highlights the outcomes of the market-based approach. Here, livelihood diversification, entrepreneurship, multi-sectoral collective enterprise development, value addition by collectives, and market linkages are activated. In such a situation, adequate efforts will be required for mainstream financial institutions supporting CBOs, good governance systems and processes, and linkages/ convergences/ partnerships with other schemes. Efforts will also be required for continuous capacity building of the CBOs, customised need-based finance, affordable and approachable education and healthcare, and vulnerability reduction.
The fourth scenario highlights the outcomes of good governance. Here, good governance systems and processes, robust monitoring mechanisms, implementation processes, enabling policies and political will, and linkages/ convergence/ partnership with other governmental schemes are ensured. In such a situation, plentiful efforts will be required for mainstream financial institutions to lend their support to CBOs and for the building of personal assets. Efforts will also be required for developing a repayment culture, climate-smart production systems, and vulnerability reduction. Good governance is likely to ensure strong institutions of the poor, development of collective enterprises, livelihood diversification, entrepreneurship, value addition by collectives, and market linkages.
In the fifth and sixth scenarios, we activated the most important concepts identified by the participants. The sixth scenario is similar to the fifth one except that the concept C14: entrepreneurship has been replaced by the concept C13: livelihood diversification. The simulation results reveal that quality of CBOs, strong institutions of the poor, community heroes driving the programme, good governance systems and processes, convergence with other schemes/ programmes, enabling policies and political will, and livelihood diversification are very critical for poverty alleviation in a developing nation.
The participants judged a relatively higher weight for the concept C1 (sensitive support structure) (Fig 1). This could be attributed to a conflict of interest on the part of the participants. Even after activating the concept C1 across policy scenarios 4 to 6, the outcome does not change. This also justifies the fact that any community-demand-driven and community-managed poverty alleviation programme has to be self-sustainable in the long-term. Therefore, while a poverty alleviation programme may make use of a support structure in its initial phase, it should persist at thriving even after the support structure has been withdrawn.
4. Contributions to FCM and poverty literature and future research directions
This section deals with contributions of the paper to FCM and poverty literature while offering a practical approach to address multi-dimensional poverty. The paper makes a two-fold contribution to FCM literature: i) knowledge capture and sample adequacy and ii) robustness of the dynamic system model. FCM sampling is often extended if additional maps keep adding new dimensions/ insights. The saturation of FCM sampling is formally measured by tracking the number of new concepts introduced in subsequent exercises and estimating an accumulation curve of concepts. When the point of saturation is reached data collection is stopped. In most studies, the saturation of FCM sampling is reported at 30–32 maps [60,62,63,66,72]. This study does demonstrate, however, that in the event of a ‘mixed-concept design’ approach when the participants gain access to concepts already identified by other sets of participant groups the latter participants continue to add new concepts, making the system much more complex and the data richer. Most FCM-based case studies published in scientific journals have taken weights of the causal interactions between the concepts. This study has not only obtained weights of the causal interactions between the concepts but also obtained weights of each concept. Results of the FCM-based simulations, by and large, match with the most critical concepts identified by participants represented by higher relative weights. This demonstrates in-depth understanding of participants of the subject matter and robustness of the system.
Scenarios are defined as ‘a plausible description of how the future may develop based on a coherent and internally consistent set of assumptions’ [97]. It also represents uncertainty as a range of plausible futures. Hence, in order to establish proper causal pathways of various poverty eradication approaches, it may be necessary to design random control trial experiments along each of the poverty eradication approaches and carry out the efficacy of each approach delineated above using the difference-in-difference micro-econometric model.
5. Conclusions
The results of our FCM-based simulations reveal that in order to eradicate poverty one needs to provide micro-finance through high-quality community organisations, enhance capabilities of the poor while providing social safety nets to the poor and vulnerable, ensure good governance within community organisations and institutions supporting them, continue to diversify livelihood options, and provide market linkages to small producers. Our findings confirm that various approaches to poverty alleviation are rather complementary and need to be implemented simultaneously for a comprehensive poverty alleviation drive. However, in relative terms, factors like good governance within community organisations and supporting institutions, high-quality community organisations based micro-financing, and enhancement of capabilities coupled with social security assurance seem to work better than a market-based approach. There is rich literature available on radical approaches like land reforms, decentralisation and poverty alleviation that have not been evaluated in this study. Nevertheless, findings of the study lead us to conclude that in order to address multi-dimensional poverty an integrated and multi-dimensional poverty alleviation approach is needed. Findings of the study are likely to help improve the design, management, and implementation of poverty eradication programmes in developing countries.
Supporting information
S1 Fig [pdf]
A simple FCM obtained during the workshop conducted in phase 1.S2 Fig [pdf]
The survey instrument used during phase 2 of the data collection.S3 Fig [pdf]
A list of all the concept categories and sub-concepts after data collection.S4 Fig [pdf]
Sensitivity analysis of the system.S5 Fig [pdf]
Various scenarios for poverty alleviation.S1 Table [xlsx]
Social cognitive map.
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- Allergic inflammation is initiated by IL-33–dependent crosstalk between mast cells and basophils
- High expression of olfactomedin-4 is correlated with chemoresistance and poor prognosis in pancreatic cancer
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- Optimization of tissue sampling for Borrelia burgdorferi in white-footed mice (Peromyscus leucopus)
- How do critical care staff respond to organisational challenge? A qualitative exploration into personality types and cognitive processing in critical care
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- Effects of supplemental creatine and guanidinoacetic acid on spatial memory and the brain of weaned Yucatan miniature pigs
- Predicting antibacterial activity from snake venom proteomes
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- An investigation of transportation practices in an Ontario swine system using descriptive network analysis
- Comparison of gridded precipitation datasets for rainfall-runoff and inundation modeling in the Mekong River Basin
- Functional interactions in patients with hemianopia: A graph theory-based connectivity study of resting fMRI signal
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- The effects of dual-task cognitive interference on gait and turning in Huntington’s disease
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- Long term impact of PositiveLinks: Clinic-deployed mobile technology to improve engagement with HIV care
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- A definition-by-example approach and visual language for activity patterns in engineering disciplines
- A network analysis revealed the essential and common downstream proteins related to inguinal hernia
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- Low risk pregnancies after a cesarean section: Determinants of trial of labor and its failure
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- Research on motion planning for an indoor spray arm based on an improved potential field method
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- HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human coronary endothelial cells
- Still standing: Recent patterns of post-fire conifer refugia in ponderosa pine-dominated forests of the Colorado Front Range
- Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling
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- Treating patients with driving phobia by virtual reality exposure therapy – a pilot study
- The impact of race relations on NFL attendance: An econometric analysis
- The potential impact of the Affordable Care Act and Medicaid expansion on reducing colorectal cancer screening disparities in African American males
- Efficient processing of raster and vector data
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- Early life experience and alterations of group composition shape the social grooming networks of former pet and entertainment chimpanzees (Pan troglodytes)
- Muscarinic modulation of M and h currents in gerbil spherical bushy cells
- Therapeutic hypothermia after out of hospital cardiac arrest improve 1-year survival rate for selective patients
- Carotid plaques and neurological impairment in patients with acute cerebral infarction
- Deep learning based image reconstruction algorithm for limited-angle translational computed tomography
- Subterranean Deuteraphorura Absolon, 1901, (Hexapoda, Collembola) of the Western Carpathians — Troglomorphy at the northern distributional limit in Europe
- Fragmentation and inefficiencies in US equity markets: Evidence from the Dow 30
- Association between coffee drinking and telomere length in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
- Hyperbaric oxygen preconditioning and the role of NADPH oxidase inhibition in postischemic acute kidney injury induced in spontaneously hypertensive rats
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- Aqueous ethanol extract of Libidibia ferrea (Mart. Ex Tul) L.P. Queiroz (juca) exhibits antioxidant and migration-inhibiting activity in human gastric adenocarcinoma (ACP02) cells
- Diagnostic differences in respiratory breathing patterns and work of breathing indices in children with Duchenne muscular dystrophy
- The role of narrative in collaborative reasoning and intelligence analysis: A case study
- Proportions of CD4 test results indicating advanced HIV disease remain consistently high at primary health care facilities across four high HIV burden countries
- Modelling of amino acid turnover in the horse during training and racing: A basis for developing a novel supplementation strategy
- Single-modal and multi-modal false arrhythmia alarm reduction using attention-based convolutional and recurrent neural networks
- Eye-gaze information input based on pupillary response to visual stimulus with luminance modulation
- Predictive value of comb-push ultrasound shear elastography for the differentiation of reactive and metastatic axillary lymph nodes: A preliminary investigation
- Type 1 diabetes is associated with an increased risk of venous thromboembolism: A retrospective population-based cohort study
- Trends of litter decomposition and soil organic matter stocks across forested swamp environments of the southeastern US
- Post mortem evaluation of inflammation, oxidative stress, and PPARγ activation in a nonhuman primate model of cardiac sympathetic neurodegeneration
- Were ancient foxes far more carnivorous than recent ones?—Carnassial morphological evidence
- Disruption in daily eating-fasting and activity-rest cycles in Indian adolescents attending school
- Plasma proteome profiling of freshwater and seawater life stages of rainbow trout (Oncorhynchus mykiss)
- Association between baseline abundance of Peptoniphilus, a Gram-positive anaerobic coccus, and wound healing outcomes of DFUs
- The earliest farming communities north of the Carpathians: The settlement at Gwoździec site 2
- Trends of the prevalence and incidence of hypertrophic cardiomyopathy in Korea: A nationwide population-based cohort study
- Percent amplitude of fluctuation: A simple measure for resting-state fMRI signal at single voxel level
- Antimicrobial activity of Asteraceae species against bacterial pathogens isolated from postmenopausal women
- Designing information provision to serve as a reminder of altruistic benefits: A case study of the risks of air pollution caused by industrialization
- Are changes in depressive symptoms, general health and residential area socio-economic status associated with trajectories of waist circumference and body mass index?
- Extracellular vesicles of U937 macrophage cell line infected with DENV-2 induce activation in endothelial cells EA.hy926
- FlexGraph: Flexible partitioning and storage for scalable graph mining
- Post-weaning infant-to-mother bonding in nutritionally independent female mice
- A little good is good enough: Ethical consumption, cheap excuses, and moral self-licensing
- Link-centric analysis of variation by demographics in mobile phone communication patterns
- Multimodal hand gesture recognition using single IMU and acoustic measurements at wrist
- Variance based weighting of multisensory head rotation signals for verticality perception
- Eligibility for hepatitis B antiviral therapy among adults in the general population in Zambia
- Tobacco smoking and health-related quality of life among university students: Mediating effect of depression
- Drivers of the opioid crisis: An appraisal of financial conflicts of interest in clinical practice guideline panels at the peak of opioid prescribing
- Nutritional inadequacies in commercial vegan foods for dogs and cats
- LTA1 and dmLT enterotoxin-based proteins activate antigen-presenting cells independent of PKA and despite distinct cell entry mechanisms
- The Shapley value for a fair division of group discounts for coordinating cooling loads
- Comparison and evaluation of the morphology of crowns generated by biogeneric design technique with CEREC chairside system
- Assessing risk factors and impact of cyberbullying victimization among university students in Myanmar: A cross-sectional study
- Incidence of hospital-acquired pressure ulcers in patients with "minimal risk" according to the "Norton-MI" scale
- Intra-host symbiont diversity in eastern Pacific cold seep tubeworms identified by the 16S-V6 region, but undetected by the 16S-V4 region
- Lipoprotein(a) plasma levels are not associated with survival after acute coronary syndromes: An observational cohort study
- Use of Nanotrap particles for the capture and enrichment of Zika, chikungunya and dengue viruses in urine
- Pancreatic secretory trypsin inhibitor reduces multi-organ injury caused by gut ischemia/reperfusion in mice
- The effect of diet on the gastrointestinal microbiome of juvenile rehabilitating green turtles (Chelonia mydas)
- Biochemical characterization of Ty1 retrotransposon protease
- Lateral pressure equalisation as a principle for designing support surfaces to prevent deep tissue pressure ulcers
- Immunomodulatory function of the cystic fibrosis modifier gene BPIFA1
- The validation of the Beijing version of the Montreal Cognitive Assessment in Chinese patients undergoing hemodialysis
- All of gene expression (AOE): An integrated index for public gene expression databases
- Characterization of the visceral and neuronal phenotype of 4L/PS-NA mice modeling Gaucher disease
- Inflammasome expression is higher in ovarian tumors than in normal ovary
- HCV genotype profile in Brazil of mono-infected and HIV co-infected individuals: A survey representative of an entire country
- Engaging with change: Information and communication technology professionals’ perspectives on change at the mid-point in the UK/EU Brexit process
- Adherence to iron-folic acid supplement and associated factors among antenatal care attending pregnant mothers in governmental health institutions of Adwa town, Tigray, Ethiopia: Cross-sectional study
- Flower, seed, and fruit development in three Tunisian species of Polygonum: Implications for their taxonomy and evolution of distyly in Polygonaceae
- Development of a risk score for prediction of poor treatment outcomes among patients with multidrug-resistant tuberculosis
- Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus
- Aqueous extract from Mangifera indica Linn. (Anacardiaceae) leaves exerts long-term hypoglycemic effect, increases insulin sensitivity and plasma insulin levels on diabetic Wistar rats
- Marine seafood production via intense exploitation and cultivation in China: Costs, benefits, and risks
- Signatures of medical student applicants and academic success
- Discovery of Jogalong virus, a novel hepacivirus identified in a Culex annulirostris (Skuse) mosquito from the Kimberley region of Western Australia
- The effects of extended photoperiod and warmth on hair growth in ponies and horses at different times of year
- Modeling the effect of prolonged ethanol exposure on global gene expression and chromatin accessibility in normal 3D colon organoids
- Clinical, cytogenetic and molecular genetic characterization of a tandem fusion translocation in a male Holstein cattle with congenital hypospadias and a ventricular septal defect
- Severity of misophonia symptoms is associated with worse cognitive control when exposed to misophonia trigger sounds
- Detection of Torque Teno Virus (TTV) and TTV-Like Minivirus in patients with presumed infectious endophthalmitis in India
- CD4 rate of increase is preferred to CD4 threshold for predicting outcomes among virologically suppressed HIV-infected adults on antiretroviral therapy
- The evolution of secondary flow phenomena and their effect on primary shock conditions in shock tubes: Experimentation and numerical model
- Estimating the basic reproduction number of a pathogen in a single host when only a single founder successfully infects
- What drugs modify the risk of iatrogenic impulse-control disorders in Parkinson’s disease? A preliminary pharmacoepidemiologic study
- Evaluating emotional distress and health-related quality of life in patients with heart failure and their family caregivers: Testing dyadic dynamics using the Actor-Partner Interdependence Model
- Community- and trophic-level responses of soil nematodes to removal of a non-native tree at different stages of invasion
- Association of ECG parameters with late gadolinium enhancement and outcome in patients with clinical suspicion of acute or subacute myocarditis referred for CMR imaging
- Sonographic measurement of normal common bile duct diameter and associated factors at the University of Gondar comprehensive specialized hospital and selected private imaging center in Gondar town, North West Ethiopia
- Catchment-scale export of antibiotic resistance genes and bacteria from an agricultural watershed in central Iowa
- Impact of multi-drug resistant bacteria on economic and clinical outcomes of healthcare-associated infections in adults: Systematic review and meta-analysis
- Characterization of a universal screening approach for congenital CMV infection based on a highly-sensitive, quantitative, multiplex real-time PCR assay
- Proof-of-concept for a non-invasive, portable, and wireless device for cardiovascular monitoring in pediatric patients
- On PTV definition for glioblastoma based on fiber tracking of diffusion tensor imaging data
- Multiregional origins of the domesticated tetraploid wheats
- Racism against Totonaco women in Veracruz: Intercultural competences for health professionals are necessary
- Increased inflammation and endothelial markers in patients with late severe post-thrombotic syndrome
- Genes associated with body weight gain and feed intake identified by meta-analysis of the mesenteric fat from crossbred beef steers
- Intraoperative computed tomography imaging for dose calculation in intraoperative electron radiation therapy: Initial clinical observations
- Multiple paedomorphic lineages of soft-substrate burrowing invertebrates: parallels in the origin of Xenocratena and Xenoturbella
- Human lung epithelial BEAS-2B cells exhibit characteristics of mesenchymal stem cells
- Simple non-mydriatic retinal photography is feasible and demonstrates retinal microvascular dilation in Chronic Obstructive Pulmonary Disease (COPD)
- Evaluating poverty alleviation strategies in a developing country
- RNAmountAlign: Efficient software for local, global, semiglobal pairwise and multiple RNA sequence/structure alignment
- Maternal depressive symptoms and children’s cognitive development: Does early childcare and child’s sex matter?
- Pan-cancer analysis of somatic mutations and epigenetic alterations in insulated neighbourhood boundaries
- Evaluation of a bioengineered ACL matrix’s osteointegration with BMP-2 supplementation
- Psychosocial profiles of physical activity fluctuation in office employees: A latent profile analysis
- Prevalence and characteristics of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) isolated from chicken meat in the province of Quebec, Canada
- HIV treatment response among female sex workers participating in a treatment as prevention demonstration project in Cotonou, Benin
- Soluble AXL as a marker of disease progression and survival in melanoma
- Using machine learning methods to determine a typology of patients with HIV-HCV infection to be treated with antivirals
- Quantifying tourism booms and the increasing footprint in the Arctic with social media data
- Gender differences influence over insomnia in Korean population: A cross-sectional study
- Impact of scion/rootstock reciprocal effects on metabolomics of fruit juice and phloem sap in grafted Citrus reticulata
- Adapting cognitive diagnosis computerized adaptive testing item selection rules to traditional item response theory
- Usability assessment of seven HIV self-test devices conducted with lay-users in Johannesburg, South Africa
- Autumn shifts in cold tolerance metabolites in overwintering adult mountain pine beetles
- Management of veterinary anaesthesia in small animals: A survey of current practice in Quebec
- Genetic structure of the European hedgehog (Erinaceus europaeus) in Denmark
- Molecular karyotyping of Siberian wild rye (Elymus sibiricus L.) with oligonucleotide fluorescence in situ hybridization (FISH) probes
- Umbilical cord separation time, predictors and healing complications in newborns with dry care
- The strain distribution in the lumbar anterior longitudinal ligament is affected by the loading condition and bony features: An in vitro full-field analysis
- Marine resource congestion in China: Identifying, measuring, and assessing its impact on sustainable development of the marine economy
- Analysis of attitudinal components towards statistics among students from different academic degrees
- Effects of fatigue induced by repeated-sprint on kicking accuracy and velocity in female soccer players
- A pre-clinical validation plan to evaluate analytical sensitivities of molecular diagnostics such as BD MAX MDR-TB, Xpert MTB/Rif Ultra and FluoroType MTB
- Leadership for success in transforming medical abortion policy in Canada
- Clinical correlates associated with the long-term response of bipolar disorder patients to lithium, valproate or lamotrigine: A retrospective study
- Determinants of change in long-acting or permanent contraceptives use in Ethiopia; A multivariate decomposition analysis of data from the Ethiopian demographic and health survey
- Forecasting stock prices with long-short term memory neural network based on attention mechanism
- On the genus Crossaster (Echinodermata: Asteroidea) and its distribution
- Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds
- Serum amyloid P component promotes formation of distinct aggregated lysozyme morphologies and reduces toxicity in Drosophila flies expressing F57I lysozyme
- Optogenetically induced cellular habituation in non-neuronal cells
- An integrated vitamin E-coated polymer hybrid nanoplatform: A lucrative option for an enhanced in vitro macrophage retention for an anti-hepatitis B therapeutic prospect
- The effect of strontium and silicon substituted hydroxyapatite electrochemical coatings on bone ingrowth and osseointegration of selective laser sintered porous metal implants
- Modeling the Theory of Planned Behaviour to predict adherence to preventive dental visits in preschool children
- Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma species in dogs with hemangiosarcoma from across the United States
- Color discrimination and gas chromatography-mass spectrometry fingerprint based on chemometrics analysis for the quality evaluation of Schizonepetae Spica
- Comparisons of recurrence-free survival and overall survival between microwave versus radiofrequency ablation treatment for hepatocellular carcinoma: A multiple centers retrospective cohort study with propensity score matching
- Transcriptome-wide identification of novel circular RNAs in soybean in response to low-phosphorus stress
- Oral misoprostol, low dose vaginal misoprostol, and vaginal dinoprostone for labor induction: Randomized controlled trial
- The association between dietary patterns before and in early pregnancy and the risk of gestational diabetes mellitus (GDM): Data from the Malaysian SECOST cohort
- Gene expression noise in a complex artificial toxin expression system
- Dynamic Extreme Aneuploidy (DEA) in the vegetable pathogen Phytophthora capsici and the potential for rapid asexual evolution
- Assertive, trainable and older dogs are perceived as more dominant in multi-dog households
- Prediction of Uropathogens by Flow Cytometry and Dip-stick Test Results of Urine Through Multivariable Logistic Regression Analysis
- Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2
- Copper to Tuscany – Coals to Newcastle? The dynamics of metalwork exchange in early Italy
- The Brazilian TP53 mutation (R337H) and sarcomas
- Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance
- Detection of amitraz resistance and reduced treatment efficacy in the Varroa Mite, Varroa destructor, within commercial beekeeping operations
- Impact of viral disease hypophagia on pig jejunal function and integrity
- Enzyme response of activated sludge to a mixture of emerging contaminants in continuous exposure
- Molecular evidence for horizontal transmission of chelonid alphaherpesvirus 5 at green turtle (Chelonia mydas) foraging grounds in Queensland, Australia
- Technology anxiety and resistance to change behavioral study of a wearable cardiac warming system using an extended TAM for older adults
- Evaluation and validation of 2D biomechanical models of the knee for radiograph-based preoperative planning in total knee arthroplasty
- Soil-Transmitted Helminth infections reduction in Bhutan: A report of 29 years of deworming
- Age-related differences in the temporal dynamics of spectral power during memory encoding
- cagA gene EPIYA motif genetic characterization from Colombian Helicobacter pylori isolates: Standardization of a molecular test for rapid clinical laboratory detection
- Mugharat an-Nachcharini: A specialized sheep-hunting camp reveals high-altitude habitats in the earliest Neolithic of the Central Levant
- Spectral characteristics of urine from patients with end-stage kidney disease analyzed using Raman Chemometric Urinalysis (Rametrix)
- Clinicians’ communication with patients receiving a MCI diagnosis: The ABIDE project
- Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling
- Fast quantitative time lapse displacement imaging of endothelial cell invasion
- Two novel mutations in MSX1 causing oligodontia
- 7,200 years old constructions and mudbrick technology: The evidence from Tel Tsaf, Jordan Valley, Israel
- Tuberculosis recurrences and predictive factors in a vulnerable population in Catalonia
- Dome-shaped macula in children and adolescents
- Barriers in the access, diagnosis and treatment completion for tuberculosis patients in central and western Nepal: A qualitative study among patients, community members and health care workers
- Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer
- Targeted transcriptomic study of the implication of central metabolic pathways in mannosylerythritol lipids biosynthesis in Pseudozyma antarctica T-34
- Preliminary evidences of the presence of extracellular DNA single stranded forms in soil
- A comparison of quality of life between patients treated with different dialysis modalities in Taiwan
- The effectiveness of substance use interventions for homeless and vulnerably housed persons: A systematic review of systematic reviews on supervised consumption facilities, managed alcohol programs, and pharmacological agents for opioid use disorder
- Spatiotemporal characteristics and driving forces of construction land expansion in Yangtze River economic belt, China
- Comparison of Monocyte Distribution Width (MDW) and Procalcitonin for early recognition of sepsis
- Morphological association between the muscles and bones in the craniofacial region
- Transcriptome analysis of Actinidia chinensis in response to Botryosphaeria dothidea infection
- Evaluating two decision aids for Australian men supporting informed decisions about prostate cancer screening: A randomised controlled trial
- Serum galectins as potential biomarkers of inflammatory bowel diseases
- Linguistic Z-number weighted averaging operators and their application to portfolio selection problem
- Comparative study on skin protection activity of polyphenol-rich extract and polysaccharide-rich extract from Sargassum vachellianum
- Real-world data about emotional stress, disability and need for social care in a German IBD patient cohort
- The regenerative compatibility: A synergy between healthy ecosystems, environmental attitudes, and restorative experiences
- Fusion of augmented reality imaging with the endoscopic view for endonasal skull base surgery; a novel application for surgical navigation based on intraoperative cone beam computed tomography and optical tracking
- Functional characterization of NK cells in Mexican pediatric patients with acute lymphoblastic leukemia: Report from the Mexican Interinstitutional Group for the Identification of the Causes of Childhood Leukemia
- Radiomics signature for prediction of lateral lymph node metastasis in conventional papillary thyroid carcinoma
- Antenatal depression and its association with adverse birth outcomes in low and middle-income countries: A systematic review and meta-analysis
- Perceptions of risk and influences of choice in pregnant women with obesity. An evidence synthesis of qualitative research
- The role of refugee and migrant migration status on medication adherence: Mediation through illness perceptions
- Job stress and emotional exhaustion at work in Spanish workers: Does unhealthy work affect the decision to drive?
- Correction: Amphibians on the hotspot: Molecular biology and conservation in the South American Atlantic Rainforest
- Sexual risk classes among youth experiencing homelessness: Relation to childhood adversities, current mental symptoms, substance use, and HIV testing
- Time for change is now: Experiences of participants in a community-based approach for iron and folic acid supplementation in a rural county in Kenya, a qualitative study
- Non-invasive genetic monitoring for the threatened valley elderberry longhorn beetle
- Statistical learning for turboshaft helicopter accidents using logistic regression
- Vegetation change over seven years in the largest protected Pacific Northwest Bunchgrass Prairie remnant
- The effect of various metal-salts on the sedimentation of soil in a water-based suspension
- Using electronic health record system triggers to target delivery of a patient-centered intervention to improve venous thromboembolism prevention for hospitalized patients: Is there a differential effect by race?
- Effects of CK2β subunit down-regulation on Akt signalling in HK-2 renal cells
- Novel broad-spectrum activity-based probes to profile malarial cysteine proteases
- Health-related quality of life in cancer patients treated with immune checkpoint inhibitors: A systematic review on reporting of methods in randomized controlled trials
- Environmental tobacco smoke (ETS) and hyperlipidemia modified by perceived work stress
- Association between opioid analgesic therapy and initiation of buprenorphine management: An analysis of prescription drug monitoring program data
- Effect of a community-based approach of iron and folic acid supplementation on compliance by pregnant women in Kiambu County, Kenya: A quasi-experimental study
- Radiocarbon dating of two old African baobabs from India
- Improvement project in higher education institutions: A BPEP-based model
- An updated evaluation of serum sHER2, CA15.3, and CEA levels as biomarkers for the response of patients with metastatic breast cancer to trastuzumab-based therapies
- Genome-wide association study of metabolic syndrome in Korean populations
- The diagnostic accuracy of liver fibrosis in non-viral liver diseases using acoustic radiation force impulse elastography: A systematic review and meta-analysis
- Drug therapy problems and treatment satisfaction among ambulatory patients with epilepsy in a specialized hospital in Ethiopia
- Short- & long-term effects of monetary and non-monetary incentives to cooperate in public good games: An experiment
- Niche modeling reveals life history shifts in birds at La Brea over the last twenty millennia
- Morphological consequences of artificial cranial deformation: Modularity and integration
- Distributed flux balance analysis simulations of serial biomass fermentation by two organisms
- Plasma kynurenines and prognosis in patients with heart failure
- Occurrence and distribution of anthropogenic persistent organic pollutants in coastal sediments and mud shrimps from the wetland of central Taiwan
- Intensified visual clutter induces increased sympathetic signalling, poorer postural control, and faster torsional eye movements during visual rotation
- Restoration of cortical symmetry and binaural function: Cortical auditory evoked responses in adult cochlear implant users with single sided deafness
- A smartphone-enabled wireless and batteryless implantable blood flow sensor for remote monitoring of prosthetic heart valve function
- Gut microbiota composition alterations are associated with the onset of diabetes in kidney transplant recipients
- Shock index and TIMI risk index as valuable prognostic tools in patients with acute coronary syndrome complicated by cardiogenic shock
- Merit overrules theory of mind when young children share resources with others
- Economic burden of maternal morbidity – A systematic review of cost-of-illness studies
- Comparison of balance changes after inspiratory muscle or Otago exercise training
- Correction: Escherichia coli and Salmonella spp. isolated from Australian meat chickens remain susceptible to critically important antimicrobial agents
- Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue
- Cell-free DNA donor fraction analysis in pediatric and adult heart transplant patients by multiplexed allele-specific quantitative PCR: Validation of a rapid and highly sensitive clinical test for stratification of rejection probability
- Immunopathogenesis of canine chronic ulcerative stomatitis
- Correction: Quantification of speech and synchrony in the conversation of adults with autism spectrum disorder
- Efficacy and safety of ultrasonic circular cyclocoagulation with second-generation probe in glaucoma: A retrospective study
- Generalizing findings from a randomized controlled trial to a real-world study of the iLookOut, an online education program to improve early childhood care and education providers’ knowledge and attitudes about reporting child maltreatment
- Self-selection of food ingredients and agricultural by-products by the house cricket, Acheta domesticus (Orthoptera: Gryllidae): A holistic approach to develop optimized diets
- Machine learning detection of Atrial Fibrillation using wearable technology
- Comparative proteomic analysis of different stages of breast cancer tissues using ultra high performance liquid chromatography tandem mass spectrometer
- A cross-sectional study of psychopathy and khat abuse among prisoners in the correctional institution in Jimma, Ethiopia
- Head impulse compensatory saccades: Visual dependence is most evident in bilateral vestibular loss
- Complementarity of empirical and process-based approaches to modelling mosquito population dynamics with Aedes albopictus as an example—Application to the development of an operational mapping tool of vector populations
- Pepsin promotes laryngopharyngeal neoplasia by modulating signaling pathways to induce cell proliferation
- When and what to test for: A cost-effectiveness analysis of febrile illness test-and-treat strategies in the era of responsible antibiotic use
- Comparison of effects and safety in providing controlled hypotension during surgery between dexmedetomidine and magnesium sulphate: A meta-analysis of randomized controlled trials
- The gene encoding the ketogenic enzyme HMGCS2 displays a unique expression during gonad development in mice
- Seroepidemiological study of rubella in Vojvodina, Serbia: 24 years after the introduction of the MMR vaccine in the national immunization programme
- Efficacy of a mitochondrion-targeting agent for reducing the level of urinary protein in rats with puromycin aminonucleoside-induced minimal-change nephrotic syndrome
- Association of endothelial nitric oxide synthase (NOS3) gene polymorphisms with primary open-angle glaucoma in a Saudi cohort
- Antitrust analysis with upward pricing pressure and cost efficiencies
- Machine learning models for identifying preterm infants at risk of cerebral hemorrhage
- Natural selection contributes to food web stability
- Pyramiding QTLs controlling tolerance against drought, salinity, and submergence in rice through marker assisted breeding
- Diversity and plant growth-promoting functions of diazotrophic/N-scavenging bacteria isolated from the soils and rhizospheres of two species of Solanum
- Sustainability effects of motor control stabilisation exercises on pain and function in chronic nonspecific low back pain patients: A systematic review with meta-analysis and meta-regression
- Sofosbuvir-based regimen for genotype 2 HCV infected patients in Taiwan: A real world experience
- The virulence domain of Shigella IcsA contains a subregion with specific host cell adhesion function
- Sequencing artifacts derived from a library preparation method using enzymatic fragmentation
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- TMEM98 is a negative regulator of FRAT mediated Wnt/ß-catenin signalling
- Modeling migration patterns in the USA under sea level rise
- Quo vadis Pantanal? Expected precipitation extremes and drought dynamics from changing sea surface temperature
- Cloud-computing and machine learning in support of country-level land cover and ecosystem extent mapping in Liberia and Gabon
- An exploratory study on the quality of patient screening and counseling for hypertension management in Tanzania
- Relation of fibroblast growth factor receptor 2 expression to hepatocellular carcinoma recurrence after liver resection
- The Brief Measure of Emotional Preoperative Stress (B-MEPS) as a new predictive tool for postoperative pain: A prospective observational cohort study
- The impact of diabetes mellitus medication on the incidence of endogenous endophthalmitis
- Correction: Chl1 DNA helicase and Scc2 function in chromosome condensation through cohesin deposition
- Clinical and pathological features of thrombotic microangiopathy influencing long-term kidney transplant outcomes
- Multidisciplinary investigation of two Egyptian child mummies curated at the University of Tartu Art Museum, Estonia (Late/Graeco-Roman Periods)
- Occupational exposure to particulate matter from air pollution in the outdoor workplaces in Almaty during the cold season
- Morphological adjustment in free-living Steinernema feltiae infective juveniles to increasing concentration of Nemafric-BL phytonematicide
- Murine Surf4 is essential for early embryonic development
- Using mHealth to improve health care delivery in India: A qualitative examination of the perspectives of community health workers and beneficiaries
- Algorithmic handwriting analysis of the Samaria inscriptions illuminates bureaucratic apparatus in biblical Israel
- Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis
- Concurrent lipidomics and proteomics on malignant plasma cells from multiple myeloma patients: Probing the lipid metabolome
- Short treatment with antalarmin alters adrenal gland receptors in the rat model of endometriosis
- Is it really always only the others who are to blame? GP’s view on medical overuse. A questionnaire study
- Serum visfatin and vaspin levels in hepatocellular carcinoma (HCC)
- Retraction: SDR9C7 Promotes Lymph Node Metastases in Patients with Esophageal Squamous Cell Carcinoma
- iTRAQ proteomics reveals the regulatory response to Magnaporthe oryzae in durable resistant vs. susceptible rice genotypes
- A smartphone-based test for the assessment of attention deficits in delirium: A case-control diagnostic test accuracy study in older hospitalised patients
- Association between tuberculosis and depression on negative outcomes of tuberculosis treatment: A systematic review and meta-analysis
- Incidence and predictors of loss to follow up among adult HIV patients on antiretroviral therapy in University of Gondar Comprehensive Specialized Hospital: A competing risk regression modeling
- Point-of-care diagnostic (POCD) method for detecting Bursaphelenchus xylophilus in pinewood using recombinase polymerase amplification (RPA) with the portable optical isothermal device (POID)
- Bioluminescent imaging of Arabidopsis thaliana using an enhanced Nano-lantern luminescence reporter system
- Biosynthetic pathway of indole-3-acetic acid in ectomycorrhizal fungi collected from northern Thailand
- Clinical implications of elevated serum interleukin-6 in IgG4-related disease
- Downscaling NLDAS-2 daily maximum air temperatures using MODIS land surface temperatures
- Sex-specific and opposite modulatory aspects revealed by PPI network and pathway analysis of ischemic stroke in humans
- Plasma Trimethylamine-N-oxide and impaired glucose regulation: Results from The Oral Infections, Glucose Intolerance and Insulin Resistance Study (ORIGINS)
- Self-esteem and other risk factors for depressive symptoms among adolescents in United Arab Emirates
- Control of the microsporidian parasite Nosema ceranae in honey bees (Apis mellifera) using nutraceutical and immuno-stimulatory compounds
- The effect of storage conditions on microbial communities in stool
- Role of donor genotype in RT-QuIC seeding activity of chronic wasting disease prions using human and bank vole substrates
- Influence of flow on phosphorus-dynamics and particle size in agricultural drainage ditch sediments
- A prospective, randomized, double-blind trial to compare body weight-adjusted and fixed doses of palonosetron for preventing postoperative nausea and vomiting in obese female patients
- Application of computerized 3D-CT texture analysis of pancreas for the assessment of patients with diabetes
- Predictive validation and forecasts of short-term changes in healthcare expenditure associated with changes in smoking behavior in the United States
- An information-based approach to handle various types of uncertainty in fuzzy bodies of evidence
- Oral magnesium supplementation for leg cramps in pregnancy—An observational controlled trial
- Health care professionals’ knowledge of commonly used sedative, analgesic and neuromuscular drugs: A single center (Rambam Health Care Campus), prospective, observational survey
- Campylobacter portucalensis sp. nov., a new species of Campylobacter isolated from the preputial mucosa of bulls
- OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model
- Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice
- Novel method to measure temporal windows based on eye movements during viewing of the Necker cube
- Whole blood transcriptomic analysis of beef cattle at arrival identifies potential predictive molecules and mechanisms that indicate animals that naturally resist bovine respiratory disease
- Effects of smoke flavoring using different wood chips and barbecuing on the formation of polycyclic aromatic hydrocarbons and heterocyclic aromatic amines in salmon fillets
- Sleep quality and sex modify the relationships between trait energy and fatigue on state energy and fatigue
- The role of peer, parental, and school norms in predicting adolescents’ attitudes and behaviours of majority and different minority ethnic groups in Croatia
- Filtered beauty in Oslo and Tokyo: A spatial frequency analysis of facial attractiveness
- The impact of rehabilitation frequency on the risk of stroke in patients with rheumatoid arthritis
- Availability, prices and affordability of selected antibiotics and medicines against non-communicable diseases in western Cameroon and northeast DR Congo
- The effect of mutations derived from mouse-adapted H3N2 seasonal influenza A virus to pathogenicity and host adaptation
- Detection of posttraumatic pneumothorax using electrical impedance tomography—An observer-blinded study in pigs with blunt chest trauma
- Educators’ perceptions of organisational readiness for implementation of a pre-adolescent transdisciplinary school health intervention for inter-generational outcomes
- Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA
- The effects of sport expertise and shot results on basketball players’ action anticipation
- Framework and algorithms for identifying honest blocks in blockchain
- Efficacy and safety of anti-viral therapy for Hepatitis B virus-associated glomerulonephritis: A meta-analysis
- Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10
- Noise reduction and quantification of fiber orientations in greyscale images
- Exploring the impact of terminology differences in blood and organ donor decision making
- Ontogenetic similarities between giraffe and sauropod neck osteological mobility
- Load transfer mechanism and critical length of anchorage zone for anchor bolt
- Income inequalities in stroke incidence and mortality: Trends in stroke-free and stroke-affected life years based on German health insurance data
- Community’s perception, experiences and health seeking behavior towards newborn illnesses in Debre Libanos District, North Shoa, Oromia, Ethiopia: Qualitative study
- Platelet indices significantly correlate with liver fibrosis in HCV-infected patients
- Reanalysis of the Bridge et al. study of suicide following release of 13 Reasons Why
- Validation of the easyscreen flavivirus dengue alphavirus detection kit based on 3base amplification technology and its application to the 2016/17 Vanuatu dengue outbreak
- The nitrate content of fresh and cooked vegetables and their health-related risks
- Bioreactor for mobilization of mesenchymal stem/stromal cells into scaffolds under mechanical stimulation: Preliminary results
- Serotonin transporter dependent modulation of food-seeking behavior
- Implicit task switching in Parkinson’s disease is preserved when on medication
- Root treatment with oxathiapiprolin, benthiavalicarb or their mixture provides prolonged systemic protection against oomycete foliar pathogens
- Real-world effectiveness and safety of ranibizumab for the treatment of myopic choroidal neovascularization: Results from the LUMINOUS study
- Non-gradient and genotype-dependent patterns of RSV gene expression
- Multiplex real-time PCR for the detection of Clavibacter michiganensis subsp. michiganensis, Pseudomonas syringae pv. tomato and pathogenic Xanthomonas species on tomato plants
- The 24-hour urinary cortisol in post-traumatic stress disorder: A meta-analysis
- Parasites modulate the gut-microbiome in insects: A proof-of-concept study
- The dynamics of shapes of vesicle membranes with time dependent spontaneous curvature
- Vascularization and biocompatibility of poly(ε-caprolactone) fiber mats for rotator cuff tear repair
- The shield of self-compassion: A buffer against disordered eating risk from physical appearance perfectionism
- Disease-specific out-of-pocket healthcare expenditure in urban Bangladesh: A Bayesian analysis
- Advanced biofilm analysis in streams receiving organic deicer runoff
- Upregulation of long non-coding RNA ROR1-AS1 promotes cell growth and migration in bladder cancer by regulation of miR-504
- Method development and validation for rapid identification of epigallocatechin gallate using ultra-high performance liquid chromatography
- Neonatal sepsis in Iran: A systematic review and meta-analysis on national prevalence and causative pathogens
- Drug-eluting versus bare-metal stents for first myocardial infarction in patients with atrial fibrillation: A nationwide population-based cohort study
- Same-day antiretroviral therapy initiation for HIV-infected adults in South Africa: Analysis of routine data
- Health-related quality of life among patients with type 2 diabetes mellitus in Eastern Province, Saudi Arabia: A cross-sectional study
- Photocatalytic biocidal effect of copper doped TiO2 nanotube coated surfaces under laminar flow, illuminated with UVA light on Legionella pneumophila
- The interoceptive hippocampus: Mouse brain endocrine receptor expression highlights a dentate gyrus (DG)–cornu ammonis (CA) challenge–sufficiency axis
- Educational attainment and HIV testing and counselling service utilisation during antenatal care in Ghana: Analysis of Demographic and Health Surveys
- Dissection of flag leaf metabolic shifts and their relationship with those occurring simultaneously in developing seed by application of non-targeted metabolomics
- Centromeres of Cucumis melo L. comprise Cmcent and two novel repeats, CmSat162 and CmSat189
- Acute high-intensity and moderate-intensity interval exercise do not change corticospinal excitability in low fit, young adults
- “I like the way I am, but I feel like I could get a little bit bigger”: Perceptions of body image among adolescents and youth living with HIV in Durban, South Africa
- Nanoparticle-based ‘turn-on’ scattering and post-sample fluorescence for ultrasensitive detection of water pollution in wider window
- The relationship of moral sensitivity and patient safety attitudes with nursing students’ perceptions of disclosure of patient safety incidents: A cross-sectional study
- Insights into the strategy of micro-environmental adaptation: Transcriptomic analysis of two alvinocaridid shrimps at a hydrothermal vent
- Thirty-day readmission after medical-surgical hospitalization for people who experience imprisonment in Ontario, Canada: A retrospective cohort study
- The effect of long-term brine discharge from desalination plants on benthic foraminifera
- Hyper-spectral response and estimation model of soil degradation in Kenli County, the Yellow River Delta
- Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017
- Significant changes in synovial fluid microRNAs after high tibial osteotomy in medial compartmental knee osteoarthritis: Identification of potential prognostic biomarkers
- Reassortment and adaptive mutations of an emerging avian influenza virus H7N4 subtype in China
- Ischemia and reperfusion injury in superficial inferior epigastric artery-based vascularized lymph node flaps
- High failure rates of protease inhibitor-based antiretroviral treatment in rural Tanzania – A prospective cohort study
- Switchable resolution in soft x-ray tomography of single cells
- Mitochondrial DNA variations and mitochondrial dysfunction in Fanconi anemia
- Extended-spectrum beta-lactamase (ESBL)-producing and non-ESBL-producing Escherichia coli isolates causing bacteremia in the Netherlands (2014 – 2016) differ in clonal distribution, antimicrobial resistance gene and virulence gene content
- Molecular characterization of blaKHM-1 encoding plasmid in an Enterobacter hormaechei subsp. hoffmannii isolate from blood culture
- PR3 levels are impaired in plasma and PBMCs from Arabs with cardiovascular diseases
- Sex differences in self-regulation in early, middle and late adolescence: A large-scale cross-sectional study
- Interaction between elevated temperature and different types of Na-salicylate treatment in Brachypodium dystachion
- A highway crash risk assessment method based on traffic safety state division
- A brain connectivity characterization of children with different levels of mathematical achievement based on graph metrics
- Quantifying the level of difficulty to treat major depressive disorder with antidepressants: Treatment Resistance to Antidepressants Evaluation Scale
- Occupational gender segregation and economic growth in U.S. local labor markets, 1980 through 2010
- The association of telomere length and telomerase activity with adverse outcomes in older patients with non-ST-elevation acute coronary syndrome
- Construction of a high-density genetic map and fine mapping of a candidate gene locus for a novel branched-spike mutant in barley
- Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease
- Parameters impacting the live birth rate per transfer after frozen single euploid blastocyst transfer
- Deep2Full: Evaluating strategies for selecting the minimal mutational experiments for optimal computational predictions of deep mutational scan outcomes
- Economic compensation interventions to increase uptake of voluntary medical male circumcision for HIV prevention: A systematic review and meta-analysis
- Distinctive effect of anesthetics on the effect of limb remote ischemic postconditioning following ischemic stroke
- Natural hybridization between Phyllagathis and Sporoxeia species produces a hybrid without reproductive organs
- Preliminary evaluation of a novel nine-biomarker profile for the prediction of autism spectrum disorder
- The impact of peer attachment on prosocial behavior, emotional difficulties and conduct problems in adolescence: The mediating role of empathy
- Spatial and climatic variables independently drive elevational gradients in ant species richness in the Eastern Himalaya
- What is the qualitative evidence concerning the risks, diagnosis, management and consequences of gastrointestinal infections in the community in the United Kingdom? A systematic review and meta-ethnography
- Naringenin protects AlCl3/D-galactose induced neurotoxicity in rat model of AD via attenuation of acetylcholinesterase levels and inhibition of oxidative stress
- Key barriers and enablers associated with uptake and continuation of oral pre-exposure prophylaxis (PrEP) in the public sector in Zimbabwe: Qualitative perspectives of general population clients at high risk for HIV
- Characterizing the University of California’s tenure-track teaching position from the faculty and administrator perspectives
- Restoration of Mal overcomes the defects of apoptosis in lung cancer cells
- Patient preferences for maintenance therapy in Crohn’s disease: A discrete-choice experiment
- Diagnostic performance of serum interferon gamma, matrix metalloproteinases, and periostin measurements for pulmonary tuberculosis in Japanese patients with pneumonia
- Hesperidin improves insulin resistance via down-regulation of inflammatory responses: Biochemical analysis and in silico validation
- Accuracy of intraocular lens power calculation formulas using a swept-source optical biometer
- Characterization of black patina from the Tiber River embankments using Next-Generation Sequencing
- Comparison of blood lactate and perceived exertion responses in two matched time-under-tension protocols
- Fibrin hydrogels are safe, degradable scaffolds for sub-retinal implantation
- Post-translational modifications of Drosophila melanogaster HOX protein, Sex combs reduced
- Problem gambling, associations with comorbid health conditions, substance use, and behavioural addictions: Opportunities for pathways to treatment
- Liganded T3 receptor β2 inhibits the positive feedback autoregulation of the gene for GATA2, a transcription factor critical for thyrotropin production
- Characterization of METTL16 as a cytoplasmic RNA binding protein
- Impact of long-term storage and freeze-thawing on eight circulating microRNAs in plasma samples
- Nanosheet wrapping-assisted coverslip-free imaging for looking deeper into a tissue at high resolution
- Assessment of dynamic cerebral autoregulation in humans: Is reproducibility dependent on blood pressure variability?
- Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study
- Validity of cerebrovascular ICD-9-CM codes in healthcare administrative databases. The Umbria Data-Value Project
- Tuberculoid leprosy: An in vivo microvascular evaluation of cutaneous lesions
- Neuromuscular blockers in the acute respiratory distress syndrome: A meta-analysis
- Identification of putative Type-I sex pheromone biosynthesis-related genes expressed in the female pheromone gland of Streltzoviella insularis
- Redefining transcriptional regulation of the APOE gene and its association with Alzheimer’s disease
- Disease-relevant mutations alter amino acid co-evolution networks in the second nucleotide binding domain of CFTR
- A bushel of viruses: Identification of seventeen novel putative viruses by RNA-seq in six apple trees
- Torque teno virus viral load is related to age, CMV infection and HLA type but not to Alzheimer's disease
- The variability of bacterial communities in both the endosphere and ectosphere of different niches in Chinese chives (Allium tuberosum)
- Tripartite factors leading to molecular divergence between human and murine smooth muscle
- Characterization of dermal skin innervation in fibromyalgia syndrome
- A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy
- A scoping review of importation and predictive models related to vector-borne diseases, pathogens, reservoirs, or vectors (1999–2016)
- Assessment of climate change impact on the malaria vector Anopheles hyrcanus, West Nile disease, and incidence of melanoma in the Vojvodina Province (Serbia) using data from a regional climate model
- Associations of cigarette smoking and burden of thoracic aortic calcification in asymptomatic individuals: A dose-response relationship
- Healthcare utilization of Mexican-American Medicare beneficiaries with and without Alzheimer’s disease and related dementias
- Evaluation of questionnaire as an instrument to measure the level of nutritional and weight gain knowledge in pregnant women in Poland. A pilot study
- TranCEP: Predicting the substrate class of transmembrane transport proteins using compositional, evolutionary, and positional information
- Non-Invasive Functional-Brain-Imaging with an OPM-based Magnetoencephalography System
- Expression of acyl-CoA-binding protein 5 from Rhodnius prolixus and its inhibition by RNA interference
- Transforming assessment of speech in children with cleft palate via online crowdsourcing
- High prevalence of off-label and unlicensed paediatric prescribing in a hospital in Indonesia during the period Aug.—Oct. 2014
- General practice management of rotator cuff related shoulder pain: A reliance on ultrasound and injection guided care
- Estimating the population size of female sex workers and transgender women in Sri Lanka
- Can helmet decrease mortality of craniocerebral trauma patients in a motorcycle accident?: A propensity score matching
- Obesity, smoking habits, and serum phosphate levels predicts mortality after life-style intervention
- Treatment of children under 4 years of age with medulloblastoma and ependymoma in the HIT2000/HIT-REZ 2005 trials: Neuropsychological outcome 5 years after treatment
- Can a semi-quantitative method replace the current quantitative method for the annual screening of microalbuminuria in patients with diabetes? Diagnostic accuracy and cost-saving analysis considering the potential health burden
- A two-arm parallel double-blind randomised controlled pilot trial of the efficacy of Omega-3 polyunsaturated fatty acids for the treatment of women with endometriosis-associated pain (PurFECT1)
- Association of benzodiazepines, opioids and tricyclic antidepressants use and falls in trauma patients: Conditional effect of age
- Burden and risk factors of cutaneous leishmaniasis in a peri-urban settlement in Kenya, 2016
- Predicting strike susceptibility and collision patterns of the common buzzard at wind turbine structures in the federal state of Brandenburg, Germany
- Embryonic thermal manipulation has short and long-term effects on the development and the physiology of the Japanese quail
- High-order radiomics features based on T2 FLAIR MRI predict multiple glioma immunohistochemical features: A more precise and personalized gliomas management
- Human-raptor conflict in rural settlements of Colombia
- Regional adaptations and parallel mutations in Feline panleukopenia virus strains from China revealed by nearly-full length genome analysis
- Long-term ecological research in southern Brazil grasslands: Effects of grazing exclusion and deferred grazing on plant and arthropod communities
- Assessment of peritoneal microbial features and tumor marker levels as potential diagnostic tools for ovarian cancer
- Survival analysis of 230 patients with unresectable hepatocellular carcinoma treated with bland transarterial embolization
- Adverse drug reaction reporting practice and associated factors among medical doctors in government hospitals in Addis Ababa, Ethiopia
- TaWAK6 encoding wall-associated kinase is involved in wheat resistance to leaf rust similar to adult plant resistance
- Deficiency syndromes in top predators associated with large-scale changes in the Baltic Sea ecosystem
- The inhibitor of apoptosis proteins antagonist Debio 1143 promotes the PD-1 blockade-mediated HIV load reduction in blood and tissues of humanized mice
- Allele specific expression of Dof genes responding to hormones and abiotic stresses in sugarcane
- Perceived relative social status and cognitive load influence acceptance of unfair offers in the Ultimatum Game
- Quantitative evaluation of choriocapillaris using optical coherence tomography and optical coherence tomography angiography in patients with central serous chorioretinopathy after half-dose photodynamic therapy
- Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties
- Extracting lung function measurements to enhance phenotyping of chronic obstructive pulmonary disease (COPD) in an electronic health record using automated tools
- Multiple fragmented habitat-patch use in an urban breeding passerine, the Short-toed Treecreeper
- Histological and immunohistochemical characterization of the porcine ocular surface
- Household environmental tobacco smoke exposure in healthy young children in Hong Kong: Prevalence and risk factors
- Wind energy development and wildlife conservation in Lithuania: A mapping tool for conflict assessment
- Characteristics and prognosis of primary treatment-naïve oral cavity squamous cell carcinoma in Norway, a descriptive retrospective study
- Effect of epoch length on intensity classification and on accuracy of measurement under controlled conditions on treadmill: Towards a better understanding of accelerometer measurement
- Peer distribution of HIV self-test kits to men who have sex with men to identify undiagnosed HIV infection in Uganda: A pilot study
- Error rates of human reviewers during abstract screening in systematic reviews
- Faecal analyses and alimentary tracers reveal the foraging ecology of two sympatric bats
- Urethral realignment with maximal urethral length and bladder neck preservation in robot-assisted radical prostatectomy: Urinary continence recovery
- Error metrics determination in functionally approximated circuits using SAT solvers
- Spatial movement pattern recognition in soccer based on relative player movements
- A novel visual ranking system based on arterial spin labeling perfusion imaging for evaluating perfusion disturbance in patients with ischemic stroke
- Prospective Validation of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) Score for Necrotizing Fasciitis of the Extremities
- The importance of transporters and cell polarization for the evaluation of human stem cell-derived hepatic cells
- Incidence, trends, and outcomes of infection sites among hospitalizations of sepsis: A nationwide study
- Morphological and functional characteristics of mitral annular calcification and their relationship to stroke
- And the nominees are: Using design-awards datasets to build computational aesthetic evaluation model
- Service delivery interventions to increase uptake of voluntary medical male circumcision for HIV prevention: A systematic review
- Multidimensional Scales of Perceived Self-Efficacy (MSPSE): Measurement invariance across Italian and Colombian adolescents
- Diversity of Mycobacteriaceae from aquatic environment at the São Paulo Zoological Park Foundation in Brazil
- A graph-based algorithm for RNA-seq data normalization
- Parents’ underestimation of their child’s weight status. Moderating factors and change over time: A cross-sectional study
- Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs
- Spatial variation in fertilizer prices in Sub-Saharan Africa
- Knowledge, beliefs, and concerns about bone health from a systematic review and metasynthesis of qualitative studies
- Successful isolation of Treponema pallidum strains from patients’ cryopreserved ulcer exudate using the rabbit model
- Effects of size and elasticity on the relation between flow velocity and wall shear stress in side-wall aneurysms: A lattice Boltzmann-based computer simulation study
- Pupil response to noxious corneal stimulation
- Incidence, risk factors and healthcare costs of central line-associated nosocomial bloodstream infections in hematologic and oncologic patients
- The impact of computed radiography and teleradiology on patients’ diagnosis and treatment in Mweso, the Democratic Republic of Congo
- Differential effects of synthetic psychoactive cathinones and amphetamine stimulants on the gut microbiome in mice
- Hepatitis B and C virus infection among HIV patients within the public and private healthcare systems in Chile: A cross-sectional serosurvey
- Increased episodes of aspiration on videofluoroscopic swallow study in children with nasogastric tube placement
- Obstructive sleep apnea and hypopnea syndrome in patients admitted in a tertiary hospital in Cameroon: Prevalence and associated factors
- Association of single nucleotide polymorphisms with dyslipidemia in antiretroviral exposed HIV patients in a Ghanaian population: A case-control study
- Sonic Hedgehog upregulation does not enhance the survival and engraftment of stem cell-derived cardiomyocytes in infarcted hearts
- The pharmacokinetic parameters and the effect of a single and repeated doses of memantine on gastric myoelectric activity in experimental pigs
- Blind method for discovering number of clusters in multidimensional datasets by regression on linkage hierarchies generated from random data
- Predictive factors of first dosage intravenous immunoglobulin-related adverse effects in children
- Description and characterization of the artisanal elasmobranch fishery on Guatemala’s Caribbean coast
- Individual and community level determinants of short birth interval in Ethiopia: A multilevel analysis
- Effects of rejection intensity and rejection sensitivity on social approach behavior in women
- The impact of IoT security labelling on consumer product choice and willingness to pay
- The development and validation of a measurement instrument to investigate determinants of health care utilisation for low back pain in Ethiopia
- Validity of the French version of the Autonomy Preference Index and its adaptation for patients with advanced cancer
- The epidemiological characteristics and spatio-temporal analysis of childhood hand, foot and mouth disease in Korea, 2011-2017
- Exponential random graph model parameter estimation for very large directed networks
- The implementation of community-based diabetes and hypertension management care program in Indonesia
- Effect of temperature variation on hospital admissions and outcomes in dogs with myxomatous mitral valve disease and new onset pulmonary edema
- The development of the Police Practices Scale: Understanding policing approaches towards street-based female sex workers in a U.S. City
- A capability approach to assess aquaculture sustainability standard compliance
- Pre-collecting lymphatic vessels form detours following obstruction of lymphatic flow and function as collecting lymphatic vessels
- Construct validity and reliability of the Talent Development Environment Questionnaire in Caribbean youth track and field athletes
- Optimization of cytotoxic activity of Nocardia sp culture broths using a design of experiments
- Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo
- Microbiota in foods from Inuit traditional hunting
- Investigating Italian disinformation spreading on Twitter in the context of 2019 European elections
- In vivo expression of peptidylarginine deiminase in Drosophila melanogaster
- Modelling zero-truncated overdispersed antenatal health care count data of women in Bangladesh
- Detection and density of breeding marsh birds in Iowa wetlands
- A lineage-specific rapid diagnostic test (Chagas Sero K-SeT) identifies Brazilian Trypanosoma cruzi II/V/VI reservoir hosts among diverse mammalian orders
- Aromatase deficiency in hematopoietic cells improves glucose tolerance in male mice through skeletal muscle-specific effects
- If host is refractory, insistent parasite goes berserk: Trypanosomatid Blastocrithidia raabei in the dock bug Coreus marginatus
- Antimicrobial resistance patterns and molecular resistance markers of Campylobacter jejuni isolates from human diarrheal cases
- Protective role of brain derived neurotrophic factor (BDNF) in obstructive sleep apnea syndrome (OSAS) patients
- An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury
- Prevalence of antiphospholipid antibodies in Behçet's disease: A systematic review and meta-analysis
- Chemical analysis of snus products from the United States and northern Europe
- Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry
- Impact of early-onset persistent stunting on cognitive development at 5 years of age: Results from a multi-country cohort study
- Aggregation of CAT tails blocks their degradation and causes proteotoxicity in S. cerevisiae
- Expression of concern: Compensatory increase of transglutaminase 2 is responsible for resistance to mTOR inhibitor treatment
- Common mental illness among epilepsy patients in Bahir Dar city, Ethiopia: A cross-sectional study
- Staging dementia based on caregiver reported patient symptoms: Implications from a latent class analysis
- Health-related quality of life and its determinants among ambulatory patients with epilepsy at Ambo General Hospital, Ethiopia: Using WHOQOL-BREF
- In silico analysis and high-risk pathogenic phenotype predictions of non-synonymous single nucleotide polymorphisms in human Crystallin beta A4 gene associated with congenital cataract
- Fungal diversity in canopy soil of silver beech, Nothofagus menziesii (Nothofagaceae)
- Referral decisions and its predictors related to orthopaedic care. A retrospective study in a novel primary care setting
- Readiness to prescribe: Using educational design to untie the Gordian Knot
- Influence of gelation on the retention of purple cactus pear extract in microencapsulated double emulsions
- Factors related to met needs for rehabilitation 6 years after stroke
- Association of cataract and sun exposure in geographically diverse populations of India: The CASE study. First Report of the ICMR-EYE SEE Study Group
- Investigation of injury severity in urban expressway crashes: A case study from Beijing
- Clinical outcomes of incident peritoneal dialysis patients coming from kidney transplantation program: A case-control study
- Evaluation of the factors influencing the housing safety awareness of residents in Shanghai
- Morphometric study of the diaphragmatic surface of the liver in the human fetus
- Food insecurity and dietary diversity among lactating mothers in the urban municipality in the mountains of Nepal
- Genetic characterization of Bacillus anthracis strains circulating in Italy from 1972 to 2018
- Promising antifungal activity of new oxadiazole against Candida krusei
- An atlas of personality, emotion and behaviour
- Long-term effects of intracranial islet grafting on cognitive functioning in a rat metabolic model of sporadic Alzheimer's disease-like dementia
- Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor
- Comparison of the myometrial transcriptome from singleton and twin pregnancies by RNA-Seq
- Adverse reproductive effects of S100A9 on bovine sperm and early embryonic development in vitro
- Functional dynamics of bacterial species in the mouse gut microbiome revealed by metagenomic and metatranscriptomic analyses
- Astrocyte senescence promotes glutamate toxicity in cortical neurons
- Primary ciliary dyskinesia and psychological well-being in adolescence
- Dipeptidyl peptidase-4 is increased in the abdominal aortic aneurysm vessel wall and is associated with aneurysm disease processes
- Primary care physician knowledge, attitudes, and diagnostic testing practices for norovirus and acute gastroenteritis
- Microfluidic-prepared DOTAP nanoparticles induce strong T-cell responses in mice
- Intraocular scattering as a predictor of driving performance in older adults with cataracts
- Reduced bone mineral density among HIV infected patients on anti-retroviral therapy in Blantyre, Malawi: Prevalence and associated factors
- Correction: Extraversion personality, perceived health and activity participation among community-dwelling aging adults in Hong Kong
- A rainwater control optimization design approach for airports based on a self-organizing feature map neural network model
- Influence of inflammasome NLRP3, and IL1B and IL2 gene polymorphisms in periodontitis susceptibility
- 18F-FDG-PET/MRI in the diagnostic work-up of limbic encephalitis
- The socioeconomic impact of orthopaedic trauma: A systematic review and meta-analysis
- Treatment patterns among patients with moderate-to-severe ulcerative colitis in the United States and Europe
- City to city learning and knowledge exchange for climate resilience in southern Africa
- Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer
- Activity-dependent switches between dynamic regimes of extracellular matrix expression
- Molecular sequencing and morphological identification reveal similar patterns in native bee communities across public and private grasslands of eastern North Dakota
- A mathematical model for assessing the effectiveness of controlling relapse in Plasmodium vivax malaria endemic in the Republic of Korea
- Cryo-focused ion beam preparation of perovskite based solar cells for atom probe tomography
- Physiological and transcriptomic responses of Lanzhou Lily (Lilium davidii, var. unicolor) to cold stress
- Unusual genome expansion and transcription suppression in ectomycorrhizal Tricholoma matsutake by insertions of transposable elements
- Estimating associations between antidepressant use and incident mild cognitive impairment in older adults with depression
- The use of telephone communication between nurse navigators and their patients
- CNP mediated selective toxicity on melanoma cells is accompanied by mitochondrial dysfunction
- HIV RNA measurement in dried blood spots of HIV-infected patients in Thailand using Abbott m2000 system
- Retraction: Oncogenic Fibulin-5 Promotes Nasopharyngeal Carcinoma Cell Metastasis through the FLJ10540/AKT Pathway and Correlates with Poor Prognosis
- Ultra-rapid cooling of ibex sperm by spheres method does not induce a vitreous extracellular state and increases the membrane damages
- Some animals are more equal than others: Validation of a new scale to measure how attitudes to animals depend on species and human purpose of use
- Observation and quantification of the morphological effect of trypan blue rupturing dead or dying cells
- The visual perception of emotion from masks
- Hexavalent chromium removal and total chromium biosorption from aqueous solution by Quercus crassipes acorn shell in a continuous up-flow fixed-bed column: Influencing parameters, kinetics, and mechanism
- The predictive value of anthropometric indices for cardiometabolic risk factors in Chinese children and adolescents: A national multicenter school-based study
- Lean back and wait for the alarm? Testing an automated alarm system for nosocomial outbreaks to provide support for infection control professionals
- Regional disparities in health care resources in traditional Chinese medicine county hospitals in China
- Analysis on hydraulic characteristics of improved sandy soil with soft rock
- Development and use of a scale to assess gender differences in appraisal of mistreatment during childbirth among Ethiopian midwifery students
- Factors for starting biosimilar TNF inhibitors in patients with rheumatic diseases in the real world
- Correction: Force field generalization and the internal representation of motor learning
- Prevalence and foetomaternal effects of iron deficiency anaemia among pregnant women in Lagos, Nigeria
- Socioeconomic risk factors for fatal opioid overdoses in the United States: Findings from the Mortality Disparities in American Communities Study (MDAC)
- Microbiome signatures in neonatal central line associated bloodstream infections
- Interventions for incarcerated adults with opioid use disorder in the United States: A systematic review with a focus on social determinants of health
- Opening gap width influences distal tibial rotation below the osteotomy site following open wedge high tibial osteotomy
- The impact of lowbush blueberry (Vaccinium angustifolium Ait.) and cranberry (Vaccinium macrocarpon Ait.) pollination on honey bee (Apis mellifera L.) colony health status
- Surveys of knowledge and awareness of antibiotic use and antimicrobial resistance in general population: A systematic review
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- Knee joint distraction in regular care for treatment of knee osteoarthritis: A comparison with clinical trial data
- Reconstruction of a regulated two-cell metabolic model to study biohydrogen production in a diazotrophic cyanobacterium Anabaena variabilis ATCC 29413
- Cochlear dysfunction is associated with styrene exposure in humans
- Intra-individual variation of particles in exhaled air and of the contents of Surfactant protein A and albumin
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- Enhanced handover mechanism using mobility prediction in wireless networks
- Association between regular exercise and asthma control among adults: The population-based Northern Finnish Asthma Study
- Pharyngeal microbiome alterations during Neisseria gonorrhoeae infection
- Assessment of the clinical utility of four NGS panels in myeloid malignancies. Suggestions for NGS panel choice or design
- Assessment of time management practice and associated factors among primary hospitals employees in north Gondar, northwest Ethiopia
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- Difference between physical therapist estimation and psychological patient-reported outcome measures in patients with low back pain
- Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness
- Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies
- Investigating cumulative effects of pre-performance routine interventions in beach volleyball serving
- Dispensing of antibiotics without prescription and associated factors in drug retail outlets of Eritrea: A simulated client method
- MicroRNA expression and DNA methylation profiles do not distinguish between primary and recurrent well-differentiated liposarcoma
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- Cytoplasmic factories, virus assembly, and DNA replication kinetics collectively constrain the formation of poxvirus recombinants
- The wavelet power spectrum of perfusion weighted MRI correlates with tumor vascularity in biopsy-proven glioblastoma samples
- Agreement between cardiovascular disease risk assessment tools: An application to the United Arab Emirates population
- Constructing HLM to examine multi-level poverty-contributing factors of farmer households: Why and how?
- Patterns of symptoms possibly indicative of cancer and associated help-seeking behaviour in a large sample of United Kingdom residents—The USEFUL study
- An automated alarm system for food safety by using electronic invoices
- Neural effects of acute stress on appetite: A magnetoencephalography study
- Use of magnetic resonance imaging to determine laterality of meniscal size in healthy volunteers
- Co-prevalence of extracranial carotid aneurysms differs between European intracranial aneurysm cohorts
- Thermal biology of two tropical lizards from the Ecuadorian Andes and their vulnerability to climate change
- When weight is an encumbrance; avoidance of stairs by different demographic groups
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- From the host's point of view: Effects of variation in burying beetle brood care and brood size on the interaction with parasitic mites
- Kernel-based Gaussian process for anomaly detection in sparse gamma-ray data
- Unmet care needs of children with ADHD
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- Identification of Korean cancer survivors’ unmet needs and desired psychosocial assistance: A focus group study
- Evaluation of inactivated Bordetella pertussis as a delivery system for the immunization of mice with Pneumococcal Surface Antigen A
- The role of moral reasoning & personality in explaining lyrical preferences
- Would you like to participate in this trial? The practice of informed consent in intrapartum research in the last 30 years
- Correction: Mutation spectrums of TSC1 and TSC2 in Chinese women with lymphangioleiomyomatosis (LAM)
- Forward lunge before and after anterior cruciate ligament reconstruction: Faster movement but unchanged knee joint biomechanics
- Challenges associated with homologous directed repair using CRISPR-Cas9 and TALEN to edit the DMD genetic mutation in canine Duchenne muscular dystrophy
- Integrated targeted serum metabolomic profile and its association with gender, age, disease severity, and pattern identification in acne
- A prospective case-control study on miRNA circulating levels in subjects born small for gestational age (SGA) evaluated from childhood into young adulthood
- Polymer-fiber-coupled field-effect sensors for label-free deep brain recordings
- Global depth perception alters local timing sensitivity
- How to detect a polytrauma patient at risk of complications: A validation and database analysis of four published scales
- Module for SWC neuron morphology file validation and correction enabled for high throughput batch processing
- Reduced gray matter volume and cortical thickness associated with traffic-related air pollution in a longitudinally studied pediatric cohort
- Recombinant human soluble thrombomodulin is associated with attenuation of sepsis-induced renal impairment by inhibition of extracellular histone release
- Human and climatic drivers affect spatial fishing patterns in a multiple-use marine protected area: The Galapagos Marine Reserve
- Correction: Leisure-time physical activity and sports in the Brazilian population: A social disparity analysis
- Application of the mixture item response theory model to the Self-Administered Food Security Survey Module for Children
- Numerical simulation of atmospheric CO2 concentration and flux over the Korean Peninsula using WRF-VPRM model during Korus-AQ 2016 campaign
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- Improved multi-parametric prediction of tissue outcome in acute ischemic stroke patients using spatial features
- Genome-wide association and epistatic interactions of flowering time in soybean cultivar
- Correction: Association between workplace bullying and burnout, professional quality of life, and turnover intention among clinical nurses
- Correction: Estimation of membrane bending modulus of stiffness tuned human red blood cells from micropore filtration studies
- Correction: Limited indirect effects of an infant pneumococcal vaccination program in an aging population
- Correction: Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats
- Fieldwork-based determination of design priorities for point-of-use drinking water quality sensors for use in resource-limited environments
- Young women’s reproductive health conversations: Roles of maternal figures and clinical practices
- Correction: Differential recordings of local field potential: A genuine tool to quantify functional connectivity
- Survival of medial versus lateral unicompartmental knee arthroplasty: A meta-analysis
- Novel MscL agonists that allow multiple antibiotics cytoplasmic access activate the channel through a common binding site
- Is it time to stop sweeping data cleaning under the carpet? A novel algorithm for outlier management in growth data
- Changes in oak (Quercus robur) photosynthesis after winter moth (Operophtera brumata) herbivory are not explained by changes in chemical or structural leaf traits
- Mutual interaction between motor cortex activation and pain in fibromyalgia: EEG-fNIRS study
- Evaluation of liposomal ciprofloxacin formulations in a murine model of anthrax
- Analysis of cholesterol in mouse brain by HPLC with UV detection
- Sugar, amino acid and inorganic ion profiling of the honeydew from different hemipteran species feeding on Abies alba and Picea abies
- Exploring prior diseases associated with incident late-onset Alzheimer’s disease dementia
- Hypertension prevalence in patients attending tertiary pain management services, a registry-based Australian cohort study
- SRL pathogenicity island contributes to the metabolism of D-aspartate via an aspartate racemase in Shigella flexneri YSH6000
- Correction: Comprehensive genome-wide analysis of the pear (Pyrus bretschneideri) laccase gene (PbLAC) family and functional identification of PbLAC1 involved in lignin biosynthesis
- Epilepsy in a melanocyte-lineage mTOR hyperactivation mouse model: A novel epilepsy model
- Water consumption and prevalence of irritable bowel syndrome among adults
- Mixed evidence for the relationship between periodontitis and Alzheimer’s disease: A bidirectional Mendelian randomization study
- Correction: Health conditions associated with overweight in climacteric women
- Correction: Determining Glomerular Filtration Rate in Homozygous Sickle Cell Disease: Utility of Serum Creatinine Based Estimating Equations
- Modelling the number of antenatal care visits in Bangladesh to determine the risk factors for reduced antenatal care attendance
- Correction: Cumulative viral load as a predictor of CD4+ T-cell response to antiretroviral therapy using Bayesian statistical models
- Dominant negative effects by inactive Spa47 mutants inhibit T3SS function and Shigella virulence
- ICOS-deficient and ICOS YF mutant mice fail to control Toxoplasma gondii infection of the brain
- Diel patterns in swimming behavior of a vertically migrating deepwater shark, the bluntnose sixgill (Hexanchus griseus)
- Life history of northern Gulf of Mexico Warsaw grouper Hyporthodus nigritus inferred from otolith radiocarbon analysis
- Physiology education for intensive care medicine residents: A 15-minute interactive peer-led flipped classroom session
- Strengthening capacity for natural sciences research: A qualitative assessment to identify good practices, capacity gaps and investment priorities in African research institutions
- Systematic scoping review of the concept of ‘genetic identity’ and its relevance for germline modification
- Height of overburden fracture based on key strata theory in longwall face
- Laboratory strains of Bacillus anthracis lose their ability to rapidly grow and sporulate compared to wildlife outbreak strains
- Improvement of classification performance of Parkinson’s disease using shape features for machine learning on dopamine transporter single photon emission computed tomography
- Comparative pharmacokinetics and pharmacodynamics of the advanced Retinol-Binding Protein 4 antagonist in dog and cynomolgus monkey
- Correction: A handy method to remove bacterial contamination from fungal cultures
- Correction: Effect of statin on life prognosis in Japanese patients undergoing hemodialysis
- Retraction: Outer Membrane Protein A (OmpA) of Shigella flexneri 2a Induces TLR2-Mediated Activation of B Cells: Involvement of Protein Tyrosine Kinase, ERK and NF-κB
- Retraction: Biofabrication of streptomycin-conjugated calcium phosphate nanoparticles using red ginseng extract and investigation of their antibacterial potential
- Receiver operating characteristic curve analysis of clinical signs for screening of convergence insufficiency in young adults
- Correction: Drivers of deforestation in the basin of the Usumacinta River: Inference on process from pattern analysis using generalised additive models
- Efficacy of fertilizing method for different potash sources in cotton (Gossypium hirsutum L.) nutrition under arid climatic conditions
- Podocyte autophagy is associated with foot process effacement and proteinuria in patients with minimal change nephrotic syndrome
- Effect of Lactobacillus acidophilus D2/CSL (CECT 4529) supplementation in drinking water on chicken crop and caeca microbiome
- Retraction: MiR-30a-5p Antisense Oligonucleotide Suppresses Glioma Cell Growth by Targeting SEPT7
- Correction: Dynamics of plasma micronutrient concentrations and their correlation with serum proteins and thyroid hormones in patients with paracoccidioidomycosis
- Impact of lower limb osteoarthritis on health-related quality of life: A cross-sectional study to estimate the expressed loss of utility in the Spanish population
- Correction: Prevalence of damaged and missing teeth among women in the southern plains of Nepal: Findings of a simplified assessment tool
- Correction: Tissue-Specific Expressed Antibody Variable Gene Repertoires
- Retraction: Immunoglobulin G Expression in Lung Cancer and Its Effects on Metastasis
- Correction: Causal knowledge promotes behavioral self-regulation: An example using climate change dynamics
- Retraction: Use of Granulocyte Colony-Stimulating Factor for the Treatment of Thin Endometrium in Experimental Rats
- Correction: Dynamic mechanical and nanofibrous topological combinatory cues designed for periodontal ligament engineering
- Correction: Evaluating the foundations that help avert antimicrobial resistance: Performance of essential water sanitation and hygiene functions in hospitals and requirements for action in Kenya
- From seed to flour: Sowing sustainability in the use of cantaloupe melon residue (Cucumis melo L. var. reticulatus)
- Core Scientific Dataset Model: A lightweight and portable model and file format for multi-dimensional scientific data
- Accounting for measurement error to assess the effect of air pollution on omic signals
- Leucine zipper transcription factor-like 1 binds adaptor protein complex-1 and 2 and participates in trafficking of transferrin receptor 1
- Barriers for tuberculosis case finding in Southwest Ethiopia: A qualitative study
- Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia
- A lower psoas muscle volume was associated with a higher rate of recurrence in male clear cell renal cell carcinoma
- Two angles of overqualification-the deviant behavior and creative performance: The role of career and survival job
- Cost-utility analysis of de-escalating biological disease-modifying anti-rheumatic drugs in patients with rheumatoid arthritis
- Efficient estimation of stereo thresholds: What slope should be assumed for the psychometric function?
- Learning efficient haptic shape exploration with a rigid tactile sensor array
- Effects of dietary supplementation with a microalga (Schizochytrium sp.) on the hemato-immunological, and intestinal histological parameters and gut microbiota of Nile tilapia in net cages
- Regional versus local wind speed and direction at a narrow beach with a high and steep foredune
- Fragmented QRS complex in patients with systemic lupus erythematosus at the time of diagnosis and its relationship with disease activity
- Severe thiamine deficiency in eastern Baltic cod (Gadus morhua)
- Transfer entropy as a variable selection methodology of cryptocurrencies in the framework of a high dimensional predictive model
- Psychometric validation of Czech version of the Sport Motivation Scale
- Correction: Multiple innate antibacterial immune defense elements are correlated in diverse ungulate species
- Recognition of personality disorder and anxiety disorder comorbidity in patients treated for depression in secondary psychiatric care
- Correction: Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform
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