Addis Ababa population-based pattern of cancer therapy, Ethiopia


Autoři: Jana Feuchtner aff001;  Assefa Mathewos aff002;  Asmare Solomon aff002;  Genebo Timotewos aff002;  Abreha Aynalem aff002;  Tigeneh Wondemagegnehu aff002;  Amha Gebremedhin aff003;  Fekadu Adugna aff002;  Mirko Griesel aff001;  Andreas Wienke aff001;  Adamu Addissie aff004;  Ahmedin Jemal aff005;  Eva Johanna Kantelhardt aff001
Působiště autorů: Institute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg, Halle, Germany aff001;  Radiotherapy Center, Addis Ababa University, Addis Ababa, Ethiopia aff002;  Division of Hematology, Department of Internal Medicine, Addis Ababa University, Addis Ababa, Ethiopia aff003;  School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia aff004;  Surveillance and Health Service Reseach, American Cancer Society, Atlanta, Georgia, United States of America aff005;  Department of Gynaecology, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Halle, Germany aff006
Vyšlo v časopise: PLoS ONE 14(9)
Kategorie: Research Article
doi: 10.1371/journal.pone.0219519

Souhrn

Cancer in Sub-Saharan Africa is becoming an important challenge for health services due to rising numbers of patients. In Addis Ababa with around 3.5 million inhabitants, more than 2000 cases are diagnosed annually. In this retrospective population-based cohort study we assessed completeness of and waiting time for cancer-therapy among patients registered in the Addis Ababa City Cancer Registry (AACCR), Ethiopia. Patient hospital files were retrieved to complete the data from AACCR. A total of 588 files were found (51% of those diagnosed from January to March 2012 and 2014). We analyzed completeness and waiting time of chemotherapy and radiotherapy; with completeness defined as ≥85% therapy received according to local guidelines. Analysis was done for the five most common cancer-types commonly treated with chemotherapy (breast, colorectal, non-Hodgkin`s lymphoma, lung and ovarian) and the four most common cancer-types commonly treated with radiotherapy (breast, cervical, head and neck and rectal). In our study, half of the patients (54.1%) received adequately dosed chemotherapy and 24.5% of patients received adequately dosed radiotherapy. The median waiting time was 2.1 months (Range: 0 to 20.72) for chemotherapy and 7 months (Range: 0.17 to 21.8) for radiotherapy. This study underscores the need for health system measures to improve cancer-directed therapy in Ethiopia, especially concerning radiotherapy.

Klíčová slova:

Medicine and health sciences – Oncology – Cancer treatment – Cancer chemotherapy – Radiation therapy – Clinical oncology – Cancers and neoplasms – Breast tumors – Breast cancer – Pharmaceutics – Drug therapy – Chemotherapy – Clinical medicine – Diagnostic medicine – Cancer detection and diagnosis – People and places – Geographical locations – Africa – Ethiopia


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2019 Číslo 9

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