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Wikipedia network analysis of cancer interactions and world influence


Autoři: Guillaume Rollin aff001;  José Lages aff001;  Dima L. Shepelyansky aff002
Působiště autorů: Institut UTINAM, CNRS, UMR 6213, OSU THETA, Université de Bourgogne Franche-Comté, Besançon, France aff001;  Laboratoire de Physique Théorique, IRSAMC, Université de Toulouse, CNRS, UPS, Toulouse, France aff002
Vyšlo v časopise: PLoS ONE 14(9)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0222508

Souhrn

We apply the Google matrix algorithms for analysis of interactions and influence of 37 cancer types, 203 cancer drugs and 195 world countries using the network of 5 416 537 English Wikipedia articles with all their directed hyperlinks. The PageRank algorithm provides a ranking of cancers which has 60% and 70% overlaps with the top 10 deadliest cancers extracted from World Health Organization GLOBOCAN 2018 and Global Burden of Diseases Study 2017, respectively. The recently developed reduced Google matrix algorithm gives networks of interactions between cancers, drugs and countries taking into account all direct and indirect links between these selected 435 entities. These reduced networks allow to obtain sensitivity of countries to specific cancers and drugs. The strongest links between cancers and drugs are in good agreement with the approved medical prescriptions of specific drugs to specific cancers. We argue that this analysis of knowledge accumulated in Wikipedia provides useful complementary global information about interdependencies between cancers, drugs and world countries.

Klíčová slova:

Social sciences – Sociology – Communications – Mass media – Encyclopedias – Online encyclopedias – Physical sciences – Mathematics – Applied mathematics – Algorithms – Research and analysis methods – Simulation and modeling – Medicine and health sciences – Oncology – Cancers and neoplasms – Breast tumors – Breast cancer – Lung and intrathoracic tumors – Hematologic cancers and related disorders – Leukemias – Lymphomas – Non-Hodgkin lymphoma – Gynecological tumors – Ovarian cancer – Genitourinary tract tumors – Prostate cancer – Hematology – Urology – Prostate diseases


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