PLOS Genetics - Číslo 9/2013

Perspective

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Take Off, Landing, and Fly Anesthesia
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Nucleosome Assembly Proteins Get SET to Defeat the Guardian of Chromosome Cohesion
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SKN-1/Nrf, A New Unfolded Protein Response Factor?

Interview

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Evidence Is Evidence: An Interview with Mary-Claire King

Research Article

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The Pathway Gene Functions together with the -Dependent Isoprenoid Biosynthetic Pathway to Orchestrate Germ Cell Migration
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Bi-modal Distribution of the Second Messenger c-di-GMP Controls Cell Fate and Asymmetry during the Cell Cycle
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An Enhancer Element Harboring Variants Associated with Systemic Lupus Erythematosus Engages the Promoter to Influence A20 Expression
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IL-17 Attenuates Degradation of ARE-mRNAs by Changing the Cooperation between AU-Binding Proteins and microRNA16
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Fusion of Large-Scale Genomic Knowledge and Frequency Data Computationally Prioritizes Variants in Epilepsy
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The Highly Prolific Phenotype of Lacaune Sheep Is Associated with an Ectopic Expression of the Gene within the Ovary
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The Genome and Development-Dependent Transcriptomes of : A Window into Fungal Evolution
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A Link between ORC-Origin Binding Mechanisms and Origin Activation Time Revealed in Budding Yeast
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Cell Interactions and Patterned Intercalations Shape and Link Epithelial Tubes in
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Extensive Divergence of Transcription Factor Binding in Embryos with Highly Conserved Gene Expression
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Type I-E CRISPR-Cas Systems Discriminate Target from Non-Target DNA through Base Pairing-Independent PAM Recognition
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Genome-Wide Mutation Avalanches Induced in Diploid Yeast Cells by a Base Analog or an APOBEC Deaminase
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An Atypical Kinase under Balancing Selection Confers Broad-Spectrum Disease Resistance in Arabidopsis
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The Uve1 Endonuclease Is Regulated by the White Collar Complex to Protect from UV Damage
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Cell-Type Specific Features of Circular RNA Expression
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A Pre-mRNA-Splicing Factor Is Required for RNA-Directed DNA Methylation in
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PKA Controls Calcium Influx into Motor Neurons during a Rhythmic Behavior
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The Prefoldin Complex Regulates Chromatin Dynamics during Transcription Elongation
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Genome Analysis of a Transmissible Lineage of Reveals Pathoadaptive Mutations and Distinct Evolutionary Paths of Hypermutators
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Divergent Transcriptional Regulatory Logic at the Intersection of Tissue Growth and Developmental Patterning
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The IDD14, IDD15, and IDD16 Cooperatively Regulate Lateral Organ Morphogenesis and Gravitropism by Promoting Auxin Biosynthesis and Transport
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Phenotypic and Genetic Consequences of Protein Damage
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Widespread Dysregulation of Peptide Hormone Release in Mice Lacking Adaptor Protein AP-3
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dTULP, the Homolog of Tubby, Regulates Transient Receptor Potential Channel Localization in Cilia
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Meiotic Recombination in Arabidopsis Is Catalysed by DMC1, with RAD51 Playing a Supporting Role
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Chromatin-Specific Regulation of Mammalian rDNA Transcription by Clustered TTF-I Binding Sites
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A Critical Role for PDGFRα Signaling in Medial Nasal Process Development
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Fatty Acid Taste Signals through the PLC Pathway in Sugar-Sensing Neurons
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Recent Acquisition of by Baka Pygmies
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The Molecular Mechanism of a -Regulatory Adaptation in Yeast
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MEIOB Targets Single-Strand DNA and Is Necessary for Meiotic Recombination
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Genotype-Environment Interactions Reveal Causal Pathways That Mediate Genetic Effects on Phenotype
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Ablating Adult Neurogenesis in the Rat Has No Effect on Spatial Processing: Evidence from a Novel Pharmacogenetic Model
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Natural Genetic Transformation Generates a Population of Merodiploids in
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Regulation of the Boundaries of Accessible Chromatin
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Guanine Holes Are Prominent Targets for Mutation in Cancer and Inherited Disease
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Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf
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Transmission of Hypervirulence Traits via Sexual Reproduction within and between Lineages of the Human Fungal Pathogen
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Stochastic Loss of Silencing of the Imprinted Allele, in a Mouse Model and Humans with Prader-Willi Syndrome, Has Functional Consequences
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Plasticity Regulators Modulate Specific Root Traits in Discrete Nitrogen Environments
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Whole-Exome Sequencing Reveals a Rapid Change in the Frequency of Rare Functional Variants in a Founding Population of Humans
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Manipulating or Superseding Host Recombination Functions: A Dilemma That Shapes Phage Evolvability
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miR-1/133a Clusters Cooperatively Specify the Cardiomyogenic Lineage by Adjustment of Myocardin Levels during Embryonic Heart Development
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Maternal Depletion of Piwi, a Component of the RNAi System, Impacts Heterochromatin Formation in
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A Genome-Wide Systematic Analysis Reveals Different and Predictive Proliferation Expression Signatures of Cancerous vs. Non-Cancerous Cells
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N-alpha-terminal Acetylation of Histone H4 Regulates Arginine Methylation and Ribosomal DNA Silencing
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PAQR-2 Regulates Fatty Acid Desaturation during Cold Adaptation in
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Functional Dissection of Regulatory Models Using Gene Expression Data of Deletion Mutants
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Dynamics of DNA Methylation in Recent Human and Great Ape Evolution
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Binding of NF-κB to Nucleosomes: Effect of Translational Positioning, Nucleosome Remodeling and Linker Histone H1
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Genome-Wide Analysis of Genes and Their Association with Natural Variation in Drought Tolerance at Seedling Stage of L
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The Locus, Exclusive to the Ambulacrarians, Encodes a Chromatin Insulator Binding Protein in the Sea Urchin Embryo
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Genetic and Anatomical Basis of the Barrier Separating Wakefulness and Anesthetic-Induced Unresponsiveness
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Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill
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Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage
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Environmental Stresses Disrupt Telomere Length Homeostasis
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Convergent Transcription Induces Dynamic DNA Methylation at Loci
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Rapid Intrahost Evolution of Human Cytomegalovirus Is Shaped by Demography and Positive Selection
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Hsp104 Suppresses Polyglutamine-Induced Degeneration Post Onset in a Drosophila MJD/SCA3 Model
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Deep Resequencing of GWAS Loci Identifies Rare Variants in , and That Are Associated with Ulcerative Colitis
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Genomic Identification of Founding Haplotypes Reveals the History of the Selfing Species
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Ago1 Interacts with RNA Polymerase II and Binds to the Promoters of Actively Transcribed Genes in Human Cancer Cells
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An Alteration in ELMOD3, an Arl2 GTPase-Activating Protein, Is Associated with Hearing Impairment in Humans
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Whole Genome Sequencing Identifies a Deletion in Protein Phosphatase 2A That Affects Its Stability and Localization in
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Growth factor independent-1 Maintains Notch1-Dependent Transcriptional Programming of Lymphoid Precursors
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and Are Required for Cellularization and Differentiation during Female Gametogenesis in
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Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations
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System-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity
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Nebula/DSCR1 Upregulation Delays Neurodegeneration and Protects against APP-Induced Axonal Transport Defects by Restoring Calcineurin and GSK-3β Signaling
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The Condition-Dependent Transcriptional Landscape of
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Cooperative Interaction between Phosphorylation Sites on PERIOD Maintains Circadian Period in
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Tracking of Chromosome and Replisome Dynamics in Reveals a Novel Chromosome Arrangement
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Fragile Site Instability in Causes Loss of Heterozygosity by Mitotic Crossovers and Break-Induced Replication
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A Shift to Organismal Stress Resistance in Programmed Cell Death Mutants
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Histone Chaperone NAP1 Mediates Sister Chromatid Resolution by Counteracting Protein Phosphatase 2A
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Predicting the Risk of Rheumatoid Arthritis and Its Age of Onset through Modelling Genetic Risk Variants with Smoking
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Analysis of Genes Reveals Redundant and Independent Functions in the Inner Ear
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VAPB/ALS8 MSP Ligands Regulate Striated Muscle Energy Metabolism Critical for Adult Survival in
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, a Direct Transcriptional Target, Modulates T-Box Factor Activity in Orofacial Clefting

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