PLOS Genetics - Číslo 8/2013

Review

32767
Transposon Domestication versus Mutualism in Ciliate Genome Rearrangements
Gene Expression Regulation by Upstream Open Reading Frames and Human Disease

Viewpoints

32767
Chromatin Sampling—An Emerging Perspective on Targeting Polycomb Repressor Proteins

Perspective

32767
Past Visits Present: TCF/LEFs Partner with ATFs for β-Catenin–Independent Activity
Fifty Years On: GWAS Confirms the Role of a Rare Variant in Lung Disease

Interview

32767
The Innocence Project at Twenty: An Interview with Barry Scheck

Research Article

32767
Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations
Re-Ranking Sequencing Variants in the Post-GWAS Era for Accurate Causal Variant Identification
Histone Variant HTZ1 Shows Extensive Epistasis with, but Does Not Increase Robustness to, New Mutations
Functional Characterisation of Alpha-Galactosidase A Mutations as a Basis for a New Classification System in Fabry Disease
A Flexible Approach for the Analysis of Rare Variants Allowing for a Mixture of Effects on Binary or Quantitative Traits
Masculinization of Gene Expression Is Associated with Exaggeration of Male Sexual Dimorphism
Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes
Endogenous Stress Caused by Faulty Oxidation Reactions Fosters Evolution of 2,4-Dinitrotoluene-Degrading Bacteria
Comparative Anatomy of Chromosomal Domains with Imprinted and Non-Imprinted Allele-Specific DNA Methylation
An Essential Function for the ATR-Activation-Domain (AAD) of TopBP1 in Mouse Development and Cellular Senescence
Depletion of Retinoic Acid Receptors Initiates a Novel Positive Feedback Mechanism that Promotes Teratogenic Increases in Retinoic Acid
Bypass of 8-oxodG
Calpain-6 Deficiency Promotes Skeletal Muscle Development and Regeneration
ATM Release at Resected Double-Strand Breaks Provides Heterochromatin Reconstitution to Facilitate Homologous Recombination
Generation of Tandem Direct Duplications by Reversed-Ends Transposition of Maize Elements
Loss of a Conserved tRNA Anticodon Modification Perturbs Cellular Signaling
Integrated Model of and Inherited Genetic Variants Yields Greater Power to Identify Risk Genes
High-Throughput Genetic and Gene Expression Analysis of the RNAPII-CTD Reveals Unexpected Connections to SRB10/CDK8
Dynamic Rewiring of the Retinal Determination Network Switches Its Function from Selector to Differentiation
β-Catenin-Independent Activation of TCF1/LEF1 in Human Hematopoietic Tumor Cells through Interaction with ATF2 Transcription Factors
Genetic Mapping of Specific Interactions between Mosquitoes and Dengue Viruses
A Highly Redundant Gene Network Controls Assembly of the Outer Spore Wall in
Origin and Functional Diversification of an Amphibian Defense Peptide Arsenal
Myc-Driven Overgrowth Requires Unfolded Protein Response-Mediated Induction of Autophagy and Antioxidant Responses in
Integrative Modeling of eQTLs and Cis-Regulatory Elements Suggests Mechanisms Underlying Cell Type Specificity of eQTLs
Species and Population Level Molecular Profiling Reveals Cryptic Recombination and Emergent Asymmetry in the Dimorphic Mating Locus of
Ras-Induced Changes in H3K27me3 Occur after Those in Transcriptional Activity
Characterization of the p53 Cistrome – DNA Binding Cooperativity Dissects p53's Tumor Suppressor Functions
Global Analysis of Fission Yeast Mating Genes Reveals New Autophagy Factors
Deficiency Suppresses Intestinal Tumorigenesis
Introns Regulate Gene Expression in in a Pab2p Dependent Pathway
Meiotic Recombination Initiation in and around Retrotransposable Elements in
Comparative Oncogenomic Analysis of Copy Number Alterations in Human and Zebrafish Tumors Enables Cancer Driver Discovery
Comparative Genomic and Functional Analysis of 100 Strains and Their Comparison with Strain GG
A Model-Based Analysis of GC-Biased Gene Conversion in the Human and Chimpanzee Genomes
Masculinization of the X Chromosome in the Pea Aphid
The Architecture of a Prototypical Bacterial Signaling Circuit Enables a Single Point Mutation to Confer Novel Network Properties
Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements
The Yeast Environmental Stress Response Regulates Mutagenesis Induced by Proteotoxic Stress
Mediator Directs Co-transcriptional Heterochromatin Assembly by RNA Interference-Dependent and -Independent Pathways
The Genome of and the Basis of Host-Microsporidian Interactions
Regulation of Sister Chromosome Cohesion by the Replication Fork Tracking Protein SeqA
Neuronal Reprograming of Protein Homeostasis by Calcium-Dependent Regulation of the Heat Shock Response
A Nuclear Calcium-Sensing Pathway Is Critical for Gene Regulation and Salt Stress Tolerance in
Cross-Species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma
: A Mouse Strain with an Ift140 Mutation That Results in a Skeletal Ciliopathy Modelling Jeune Syndrome
The Relative Contribution of Proximal 5′ Flanking Sequence and Microsatellite Variation on Brain Vasopressin 1a Receptor () Gene Expression and Behavior
Combining Quantitative Genetic Footprinting and Trait Enrichment Analysis to Identify Fitness Determinants of a Bacterial Pathogen
Computational Identification of Diverse Mechanisms Underlying Transcription Factor-DNA Occupancy
GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm
H2A.Z Acidic Patch Couples Chromatin Dynamics to Regulation of Gene Expression Programs during ESC Differentiation
Identification of DSB-1, a Protein Required for Initiation of Meiotic Recombination in , Illuminates a Crossover Assurance Checkpoint
Binding of TFIIIC to SINE Elements Controls the Relocation of Activity-Dependent Neuronal Genes to Transcription Factories
Global Analysis of the Sporulation Pathway of
Genetic Circuits that Govern Bisexual and Unisexual Reproduction in
Deletion of microRNA-80 Activates Dietary Restriction to Extend Healthspan and Lifespan
The Enhancer Landscape during Early Neocortical Development Reveals Patterns of Dense Regulation and Co-option
Sociogenomics of Cooperation and Conflict during Colony Founding in the Fire Ant
The Intronic Long Noncoding RNA Recruits PRC2 to the Promoter, Reducing the Expression of and Increasing Cell Proliferation
The , p.E318G Variant Increases the Risk of Alzheimer's Disease in -ε4 Carriers
The Wilms Tumor Gene, , Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans
Reversible and Rapid Transfer-RNA Deactivation as a Mechanism of Translational Repression in Stress
QTL Analysis of High Thermotolerance with Superior and Downgraded Parental Yeast Strains Reveals New Minor QTLs and Converges on Novel Causative Alleles Involved in RNA Processing
Genome Wide Association Identifies Novel Loci Involved in Fungal Communication
A Recessive Founder Mutation in Regulator of Telomere Elongation Helicase 1, , Underlies Severe Immunodeficiency and Features of Hoyeraal Hreidarsson Syndrome
Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci
Causal and Synthetic Associations of Variants in the Gene Cluster with Alpha1-antitrypsin Serum Levels
Hard Selective Sweep and Ectopic Gene Conversion in a Gene Cluster Affording Environmental Adaptation
Brittle Culm1, a COBRA-Like Protein, Functions in Cellulose Assembly through Binding Cellulose Microfibrils
Chromosomal Copy Number Variation, Selection and Uneven Rates of Recombination Reveal Cryptic Genome Diversity Linked to Pathogenicity
The Ribosomal Protein Rpl22 Controls Ribosome Composition by Directly Repressing Expression of Its Own Paralog, Rpl22l1
Ras1 Acts through Duplicated Cdc42 and Rac Proteins to Regulate Morphogenesis and Pathogenesis in the Human Fungal Pathogen
The DSB-2 Protein Reveals a Regulatory Network that Controls Competence for Meiotic DSB Formation and Promotes Crossover Assurance
Recurrent Modification of a Conserved -Regulatory Element Underlies Fruit Fly Pigmentation Diversity
Associations of Mitochondrial Haplogroups B4 and E with Biliary Atresia and Differential Susceptibility to Hydrophobic Bile Acid
The Conditional Nature of Genetic Interactions: The Consequences of Wild-Type Backgrounds on Mutational Interactions in a Genome-Wide Modifier Screen
A Critical Function of Mad2l2 in Primordial Germ Cell Development of Mice
A Role for CF1A 3′ End Processing Complex in Promoter-Associated Transcription
Vitellogenin Underwent Subfunctionalization to Acquire Caste and Behavioral Specific Expression in the Harvester Ant

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