PLOS Genetics - Číslo 8/2013

Review

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Transposon Domestication versus Mutualism in Ciliate Genome Rearrangements
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Gene Expression Regulation by Upstream Open Reading Frames and Human Disease

Viewpoints

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Chromatin Sampling—An Emerging Perspective on Targeting Polycomb Repressor Proteins

Perspective

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Past Visits Present: TCF/LEFs Partner with ATFs for β-Catenin–Independent Activity
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Fifty Years On: GWAS Confirms the Role of a Rare Variant in Lung Disease

Interview

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The Innocence Project at Twenty: An Interview with Barry Scheck

Research Article

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Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations
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H2A.Z Acidic Patch Couples Chromatin Dynamics to Regulation of Gene Expression Programs during ESC Differentiation
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Sociogenomics of Cooperation and Conflict during Colony Founding in the Fire Ant
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The Enhancer Landscape during Early Neocortical Development Reveals Patterns of Dense Regulation and Co-option
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Deletion of microRNA-80 Activates Dietary Restriction to Extend Healthspan and Lifespan
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Genetic Circuits that Govern Bisexual and Unisexual Reproduction in
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Global Analysis of the Sporulation Pathway of
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Binding of TFIIIC to SINE Elements Controls the Relocation of Activity-Dependent Neuronal Genes to Transcription Factories
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Identification of DSB-1, a Protein Required for Initiation of Meiotic Recombination in , Illuminates a Crossover Assurance Checkpoint
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GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm
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The , p.E318G Variant Increases the Risk of Alzheimer's Disease in -ε4 Carriers
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Computational Identification of Diverse Mechanisms Underlying Transcription Factor-DNA Occupancy
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Combining Quantitative Genetic Footprinting and Trait Enrichment Analysis to Identify Fitness Determinants of a Bacterial Pathogen
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The Relative Contribution of Proximal 5′ Flanking Sequence and Microsatellite Variation on Brain Vasopressin 1a Receptor () Gene Expression and Behavior
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: A Mouse Strain with an Ift140 Mutation That Results in a Skeletal Ciliopathy Modelling Jeune Syndrome
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Cross-Species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma
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A Nuclear Calcium-Sensing Pathway Is Critical for Gene Regulation and Salt Stress Tolerance in
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Neuronal Reprograming of Protein Homeostasis by Calcium-Dependent Regulation of the Heat Shock Response
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The Intronic Long Noncoding RNA Recruits PRC2 to the Promoter, Reducing the Expression of and Increasing Cell Proliferation
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The Wilms Tumor Gene, , Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans
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The Genome of and the Basis of Host-Microsporidian Interactions
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The Ribosomal Protein Rpl22 Controls Ribosome Composition by Directly Repressing Expression of Its Own Paralog, Rpl22l1
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A Role for CF1A 3′ End Processing Complex in Promoter-Associated Transcription
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A Critical Function of Mad2l2 in Primordial Germ Cell Development of Mice
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The Conditional Nature of Genetic Interactions: The Consequences of Wild-Type Backgrounds on Mutational Interactions in a Genome-Wide Modifier Screen
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Associations of Mitochondrial Haplogroups B4 and E with Biliary Atresia and Differential Susceptibility to Hydrophobic Bile Acid
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Recurrent Modification of a Conserved -Regulatory Element Underlies Fruit Fly Pigmentation Diversity
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The DSB-2 Protein Reveals a Regulatory Network that Controls Competence for Meiotic DSB Formation and Promotes Crossover Assurance
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Ras1 Acts through Duplicated Cdc42 and Rac Proteins to Regulate Morphogenesis and Pathogenesis in the Human Fungal Pathogen
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Chromosomal Copy Number Variation, Selection and Uneven Rates of Recombination Reveal Cryptic Genome Diversity Linked to Pathogenicity
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Reversible and Rapid Transfer-RNA Deactivation as a Mechanism of Translational Repression in Stress
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Brittle Culm1, a COBRA-Like Protein, Functions in Cellulose Assembly through Binding Cellulose Microfibrils
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Hard Selective Sweep and Ectopic Gene Conversion in a Gene Cluster Affording Environmental Adaptation
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Causal and Synthetic Associations of Variants in the Gene Cluster with Alpha1-antitrypsin Serum Levels
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Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci
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A Recessive Founder Mutation in Regulator of Telomere Elongation Helicase 1, , Underlies Severe Immunodeficiency and Features of Hoyeraal Hreidarsson Syndrome
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Genome Wide Association Identifies Novel Loci Involved in Fungal Communication
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QTL Analysis of High Thermotolerance with Superior and Downgraded Parental Yeast Strains Reveals New Minor QTLs and Converges on Novel Causative Alleles Involved in RNA Processing
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Regulation of Sister Chromosome Cohesion by the Replication Fork Tracking Protein SeqA
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Mediator Directs Co-transcriptional Heterochromatin Assembly by RNA Interference-Dependent and -Independent Pathways
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Re-Ranking Sequencing Variants in the Post-GWAS Era for Accurate Causal Variant Identification
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Depletion of Retinoic Acid Receptors Initiates a Novel Positive Feedback Mechanism that Promotes Teratogenic Increases in Retinoic Acid
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High-Throughput Genetic and Gene Expression Analysis of the RNAPII-CTD Reveals Unexpected Connections to SRB10/CDK8
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Integrated Model of and Inherited Genetic Variants Yields Greater Power to Identify Risk Genes
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Loss of a Conserved tRNA Anticodon Modification Perturbs Cellular Signaling
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Generation of Tandem Direct Duplications by Reversed-Ends Transposition of Maize Elements
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ATM Release at Resected Double-Strand Breaks Provides Heterochromatin Reconstitution to Facilitate Homologous Recombination
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Calpain-6 Deficiency Promotes Skeletal Muscle Development and Regeneration
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Bypass of 8-oxodG
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An Essential Function for the ATR-Activation-Domain (AAD) of TopBP1 in Mouse Development and Cellular Senescence
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β-Catenin-Independent Activation of TCF1/LEF1 in Human Hematopoietic Tumor Cells through Interaction with ATF2 Transcription Factors
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Comparative Anatomy of Chromosomal Domains with Imprinted and Non-Imprinted Allele-Specific DNA Methylation
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Endogenous Stress Caused by Faulty Oxidation Reactions Fosters Evolution of 2,4-Dinitrotoluene-Degrading Bacteria
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Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes
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Masculinization of Gene Expression Is Associated with Exaggeration of Male Sexual Dimorphism
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A Flexible Approach for the Analysis of Rare Variants Allowing for a Mixture of Effects on Binary or Quantitative Traits
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Functional Characterisation of Alpha-Galactosidase A Mutations as a Basis for a New Classification System in Fabry Disease
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Histone Variant HTZ1 Shows Extensive Epistasis with, but Does Not Increase Robustness to, New Mutations
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Dynamic Rewiring of the Retinal Determination Network Switches Its Function from Selector to Differentiation
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Genetic Mapping of Specific Interactions between Mosquitoes and Dengue Viruses
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The Yeast Environmental Stress Response Regulates Mutagenesis Induced by Proteotoxic Stress
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Introns Regulate Gene Expression in in a Pab2p Dependent Pathway
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Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements
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The Architecture of a Prototypical Bacterial Signaling Circuit Enables a Single Point Mutation to Confer Novel Network Properties
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Masculinization of the X Chromosome in the Pea Aphid
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A Model-Based Analysis of GC-Biased Gene Conversion in the Human and Chimpanzee Genomes
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Comparative Genomic and Functional Analysis of 100 Strains and Their Comparison with Strain GG
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Comparative Oncogenomic Analysis of Copy Number Alterations in Human and Zebrafish Tumors Enables Cancer Driver Discovery
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Meiotic Recombination Initiation in and around Retrotransposable Elements in
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Deficiency Suppresses Intestinal Tumorigenesis
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A Highly Redundant Gene Network Controls Assembly of the Outer Spore Wall in
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Global Analysis of Fission Yeast Mating Genes Reveals New Autophagy Factors
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Characterization of the p53 Cistrome – DNA Binding Cooperativity Dissects p53's Tumor Suppressor Functions
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Ras-Induced Changes in H3K27me3 Occur after Those in Transcriptional Activity
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Species and Population Level Molecular Profiling Reveals Cryptic Recombination and Emergent Asymmetry in the Dimorphic Mating Locus of
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Integrative Modeling of eQTLs and Cis-Regulatory Elements Suggests Mechanisms Underlying Cell Type Specificity of eQTLs
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Myc-Driven Overgrowth Requires Unfolded Protein Response-Mediated Induction of Autophagy and Antioxidant Responses in
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Origin and Functional Diversification of an Amphibian Defense Peptide Arsenal
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Vitellogenin Underwent Subfunctionalization to Acquire Caste and Behavioral Specific Expression in the Harvester Ant

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