PLOS Genetics - Číslo 4/2013

Perspective

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A Big Catch for Germ Cell Tumour Research
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The Quest for the Identification of Genetic Variants in Unexplained Cardiac Arrest and Idiopathic Ventricular Fibrillation
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Focusing In on the Complex Genetics of Myopia

Review

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The G4 Genome

Research Article

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Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the Downregulation of a Gene Cluster That Targets NF-kB
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An Essential Role for Zygotic Expression in the Pre-Cellular Drosophila Embryo
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Signatures of Diversifying Selection in European Pig Breeds
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The Chromosomal Passenger Protein Birc5b Organizes Microfilaments and Germ Plasm in the Zebrafish Embryo
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The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3
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Regulates Synaptic Development and Endocytosis by Suppressing Filamentous Actin Assembly
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Sensory Neuron-Derived Eph Regulates Glomerular Arbors and Modulatory Function of a Central Serotonergic Neuron
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Analysis of Rare, Exonic Variation amongst Subjects with Autism Spectrum Disorders and Population Controls
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Scavenger Receptors Mediate the Role of SUMO and Ftz-f1 in Steroidogenesis
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DNA Double-Strand Breaks Coupled with PARP1 and HNRNPA2B1 Binding Sites Flank Coordinately Expressed Domains in Human Chromosomes
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High-Resolution Mapping of H1 Linker Histone Variants in Embryonic Stem Cells
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Comparative Genomics of and the Bacterial Species Concept
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Genetic and Biochemical Assays Reveal a Key Role for Replication Restart Proteins in Group II Intron Retrohoming
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Genome-Wide Association Studies Identify Two Novel Mutations Responsible for an Atypical Hyperprolificacy Phenotype in Sheep
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The Genetic Correlation between Height and IQ: Shared Genes or Assortative Mating?
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Comprehensive Assignment of Roles for Typhimurium Genes in Intestinal Colonization of Food-Producing Animals
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The Genome Organization of Reflects Its Lifestyle
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Disruption of TTDA Results in Complete Nucleotide Excision Repair Deficiency and Embryonic Lethality
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Differential Association of the Conserved SUMO Ligase Zip3 with Meiotic Double-Strand Break Sites Reveals Regional Variations in the Outcome of Meiotic Recombination
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Transposable Elements Are Major Contributors to the Origin, Diversification, and Regulation of Vertebrate Long Noncoding RNAs
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Genetic and Genomic Architecture of the Evolution of Resistance to Antifungal Drug Combinations
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Bisphenol A Exposure Disrupts Genomic Imprinting in the Mouse
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Intrinsic Epigenetic Regulation of the D4Z4 Macrosatellite Repeat in a Transgenic Mouse Model for FSHD
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Breakpoint Analysis of Transcriptional and Genomic Profiles Uncovers Novel Gene Fusions Spanning Multiple Human Cancer Types
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Continent-Wide Decoupling of Y-Chromosomal Genetic Variation from Language and Geography in Native South Americans
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Asynchronous Replication, Mono-Allelic Expression, and Long Range -Effects of
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Coordinated Cell Type–Specific Epigenetic Remodeling in Prefrontal Cortex Begins before Birth and Continues into Early Adulthood
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DJ-1 Decreases Neural Sensitivity to Stress by Negatively Regulating Daxx-Like Protein through dFOXO
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Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1
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Identification of , a Retrotransposon-Derived Imprinted Gene, as a Novel Driver of Hepatocarcinogenesis
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Npc1 Acting in Neurons and Glia Is Essential for the Formation and Maintenance of CNS Myelin
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Site-Specific Phosphorylation of the DNA Damage Response Mediator Rad9 by Cyclin-Dependent Kinases Regulates Activation of Checkpoint Kinase 1
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Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
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Insulators Target Active Genes to Transcription Factories and Polycomb-Repressed Genes to Polycomb Bodies
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Evolution after Introduction of a Novel Metabolic Pathway Consistently Leads to Restoration of Wild-Type Physiology
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A Nonsynonymous Polymorphism in as a Risk Factor for Human Unexplained Cardiac Arrest with Documented Ventricular Fibrillation
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Six Homeoproteins Directly Activate Expression in the Gene Regulatory Networks That Control Early Myogenesis
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The Hourglass and the Early Conservation Models—Co-Existing Patterns of Developmental Constraints in Vertebrates
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Smaug/SAMD4A Restores Translational Activity of CUGBP1 and Suppresses CUG-Induced Myopathy
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Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human–Neandertal Divergence
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Extensive Natural Epigenetic Variation at a Originated Gene
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Mouse Oocyte Methylomes at Base Resolution Reveal Genome-Wide Accumulation of Non-CpG Methylation and Role of DNA Methyltransferases
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The Environment Affects Epistatic Interactions to Alter the Topology of an Empirical Fitness Landscape
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TIP48/Reptin and H2A.Z Requirement for Initiating Chromatin Remodeling in Estrogen-Activated Transcription
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Aconitase Causes Iron Toxicity in Mutants
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Tbx2 Terminates Shh/Fgf Signaling in the Developing Mouse Limb Bud by Direct Repression of
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Mondo/ChREBP-Mlx-Regulated Transcriptional Network Is Essential for Dietary Sugar Tolerance in
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Sex-Differential Selection and the Evolution of X Inactivation Strategies
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Identification of a Tissue-Selective Heat Shock Response Regulatory Network
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Phosphorylation-Coupled Proteolysis of the Transcription Factor MYC2 Is Important for Jasmonate-Signaled Plant Immunity
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RpoS Plays a Central Role in the SOS Induction by Sub-Lethal Aminoglycoside Concentrations in
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Rtt109 Prevents Hyper-Amplification of Ribosomal RNA Genes through Histone Modification in Budding Yeast
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Rod Monochromacy and the Coevolution of Cetacean Retinal Opsins
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Neutral Genomic Microevolution of a Recently Emerged Pathogen, Serovar Agona
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High-Resolution Mapping of Spontaneous Mitotic Recombination Hotspots on the 1.1 Mb Arm of Yeast Chromosome IV
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Senataxin Plays an Essential Role with DNA Damage Response Proteins in Meiotic Recombination and Gene Silencing
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Reference-Free Population Genomics from Next-Generation Transcriptome Data and the Vertebrate–Invertebrate Gap
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Dialects of the DNA Uptake Sequence in
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SNF5 Is an Essential Executor of Epigenetic Regulation during Differentiation
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Genetic Requirements for Signaling from an Autoactive Plant NB-LRR Intracellular Innate Immune Receptor
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The Tissue-Specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of Pre-mRNAs in the Brain
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ATP-Dependent Chromatin Remodeling by Cockayne Syndrome Protein B and NAP1-Like Histone Chaperones Is Required for Efficient Transcription-Coupled DNA Repair
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Functional 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases
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All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs
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Tissue Homeostasis in the Wing Disc of : Immediate Response to Massive Damage during Development
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Cytotoxic Chromosomal Targeting by CRISPR/Cas Systems Can Reshape Bacterial Genomes and Expel or Remodel Pathogenicity Islands
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Mutations in Predispose Zebrafish and Humans to Seminomas
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Iron-Responsive miR-485-3p Regulates Cellular Iron Homeostasis by Targeting Ferroportin
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Functional Dissection of the Condensin Subunit Cap-G Reveals Its Exclusive Association with Condensin I

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