1. Coresh J, Selvin E, Stevens LA et al. Prevalence of Chronic Kidney Disease in the United States. JAMA 2007; 298: 2038–2047.
2. Moeller S, Gioberge S, Brown G. ESRD patients in 2001: global overview of patients, treatment modalities and development trends. Nephrol Dial Transplant 2002; 17: 2071–2076.
3. U.S. Renal Data System, USRDS 2010 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2010.
4. U.S. Renal Data System, USRDS 2003 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2003, www.usrds.org
5. Rychlík I, Lopot F. Statistická ročenka dialyzační léčby v České republice v roce 2010. www.nefrol.cz.
6. Rychlík I, Lopot F. Statistická ročenka dialyzační léčby v České republice v roce 2009. www.nefrol.cz.
7. Halperin ML, Jungas RL. Metabolic production and renal disposal of hydrogen ions. Kidney Int 1983; 24: 709–711.
8. Kurtz I, Maher T, Hulter HN et al. Effect of diet on plasma acid-base composition in normal humans. Kidney Int 1983; 24: 670–680.
9. Kalantar-Zadeh K, Mehrotra R, Fouque D et al. Metabolic acidosis and malnutrition-inflamation complex syndrome in chronic renal failure. Semin Dial 2004; 17: 455–465.
10. Tian XK, Shan YS, Zhe XW et al. Metabolic acidosis in peritoneal dialysis patients: the role of residual renal function. Blood Purif 2005; 23: 459–465.
11. Klaboch J, Opatrná S, Matousovic K et al. Acid-base balance in peritoneal dialysis patients: a Stewart-Fencl analysis. Ren Fail 2009; 31: 625–632.
12. Uribarri J, Buquing J, Oh MS. Acid-base balance in chronic peritoneal dialysis patients. Kidney Int 1995; 47: 269–273.
13. Urribari J, Zia M, Mahmood J et al. Acid production in chronic hemodialysis patients. J Am Soc Nephrol 1998; 9: 114–120.
14. Oh MS, Uribarri J. What unique Acid-Base Consideration Exist in Dialysis Patients. Semin Dial 2004; 17: 351–354.
15. Morrane O, Froissart M, Rossert J et al. Timing of onset of CKD-related metabolic complications. J Am Soc Nephrol 2009; 20: 164–171.
16. Eustace JA, Astor B, Muntner PM et al. Prevalence of acidosis and inflammation and their association with low serum albumin in chronic kidney disease. Kidney Int 2004; 65: 1031–1040.
17. Van Slyke DD, Linder GC, Hiller A et al. The excretion of ammonia and titratable acid in nephritis. J Clin Invest 1926; 2: 255–288.
18. Simpson DP. Control of hydrogen ion homeostasis and renal acidosis. Medicine (Baltimore) 1971; 50: 503–541.
19. Simon E, Martin D, Buerkert J. Contribution of individual superficial nephron segment to ammonium hendling in chronic metabolic acidosis in the rat. Evidence for ammonia disequilibrium in the renal cortex. J Clin Invest 1985; 76: 855–864.
20. Schoolwerth AC, Sandler RS, Hoffman PM et al. Effects of nephron reduction and dietary protein content on renal ammoniagenesis in the rat. Kidney Int 1975; 7: 397–404.
21. Nath KA, Hostetter TH. Pathyphysiology of chronic tubulointerstitial disease in rats. Interaction of dietary acid load, ammonia and complement C3. J Clin Invest 1985; 76: 667–675.
22. Kim HY, Baylis C, Verlander JW et al. Effect of reduced renal mass on renal ammonia transporter family, Rh C glycoprotein and Rh B glycoprotein, expression. Am J Physiol Renal Physiol 2007; 293: F1238–F1247.
23. Story DA, Tosolini A, Bellomo R et al. Plasma acid-base changes in chronic renal failure: A Stewart analysis. Int J Artif Organs 2005; 28: 961–965.
24. Stewart PA. Modern quantitative acid-base chemistry. Can J Physiol Pharmacol 1983; 61: 1444–1461.
25. Schück O, Matoušovic K. Relation between pH and the strong ion difference (SID) in body fluids. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2005; 149: 69–73.
26. Figge J. An educational web site about modern human acid-base physiology: The Figge-Fencl quantitative physicochemical model of human acid-base physiology. www. acid-base.org.
27. Bushinsky DA. Nephrology forum: The contribution of acidosis to renal osteodystrophy. Kidney Int 1999; 47: 1816–1832.
28. Sulková SD. Význam včasné diagnózy renální osteodystrofie. Vnitř Lék 2006; 52: 300–301.
29. Lemann J, Bushinsky DA, Hamm LL. Bone buffering of acid and base in humans. Am J Physiol 2003; 285: F811–F832.
30. Krieger NS, Sessler NE, Bushinsky DA. Acidosis inhibits osteoblastic and stimulates osteoclastic activity in vitro. Am J Physiol 1992; 262: F442–F448.
31. Kraut JA, Mishler DR, Singer FR et al. The effects of metabolic acidosis on bone formation and bone resorption in the rat. Kidney Int 1986; 30: 694–700.
32. Chan YL, Sardie E, Mason RS et al. The effect of metabolic acidosis on vitamin D metabolism and bone histology in uremic rats. Calcif Tissue Int 1985; 37: 158–164.
33. Kraut JA. Disturbances of acid-base balance and bone disease in end-stage renal disease. Semin Dial 2000; 13: 261–265.
34. Martin KJ, Freitag JJ, Bellorin-Font E et al. The effect of acute acidosis on the uptake of parathyroid hormone and the production of adenosine 3´,5´-monophosphate by isolated perfused bone. Endocrinology 1980; 106: 1607–1611.
35. Coe FL, Firpo DJ, Hollandsworth L et al. Effect of acute and chronic metabolic acidosis on serum immunoreactive parathyroid hormone in man. Kidney Int 1999; 8: 262–273.
36. May RC, Kelly RA, Mitch WE. Mechanisms for defects in muscle protein metabolism in rats with chronic uremia: The influence of metabolic acidosis. J Clin Invest 1987; 79: 1099–1103.
37. Mitch WE, Price SR. Mechanisms activating proteolysis to cause muscle atrophy in catabolic conditions. J Ren Nutr 2003; 13: 149–152.
38. Mitch WE Mechanism causing loss of lean body mass in kidney disease. Am J Clin Nutr 1998; 67: 359–366.
39. Bailey JL, Wang XN, England BK et al. The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding protein of the ATP-dependent ubiquitin-proteosome pathway. J Clin Invest 1996; 97: 1447–1453.
40. Greiger S, Mitch WE. Mechanisms for protein catabolism in uremia – Metabolic acidosis and activation of protelytic pathways. Miner Electrol Metab 1992; 18: 233–236.
41. Ballmer PE, Mc Nurlan MA, Hulter HN et al. Chronic metabolic acidosis decrease albumin synthesis and induced negative nitrogen balance in humans. J Clin Invest 1995; 95: 39–45.
42. Eustace JA, Astor B, Munter PM et al. Prevalence of acidosis and inflammation and their association with low serum albumin in chronic kidney disease. Kidney Int 2004; 65: 1031–1040.
43. Mc Sherry E, Morris RC. Attainment and maintenance of normal stature with alkali therapy in infant and children with classic renal tubular acidosis. J Clin Invest 1978; 61: 509–527.
44. Mahan JD, Warady BA. Assessment and treatment of short stature in pediatric patients with chronic kidney disease: a consensus statement. Pediatr Nephrol 2006; 21: 917–930.
45. Kleinknecht C, Maniar S, Zhou XA et al. Acidosis prevents growth hormone-induced growth in experimental uremia. Pediatr Nephrol 1996; 10: 256–260.
46. Challa A, Chan W, Krieg RJJ et al. Effect of metabolic acidosis on the expression of insulin-like growth hormone receptor. Kidney Int 1993; 44: 1224–1227.
47. Ordonez FA, Santos F, Martinez V et al. Resistance to growth hormone and insulin-like growth factor-I in acidotic rats. Pediatr Nephrol 2000; 14: 720–725.
48. Whittaker J, Cuthbert C, Hammond VA et al. The effects of metabolic acidosis in vivo on insulin binding to isolated rat adipocytes. Metabolism 1982; 31: 553–557.
49. Igarashi M, Yamatani K, Fukase N et al. Effect of acidosis on insulin binding and glucose uptake in isolated rat adipocytes. J Exp Med 1993; 169: 205–213.
50. Sonikian M, Gogusev J, Zingraff J et al. Potential effect of metabolic acidosis on beta2-microglobulin generation: In vivo and in vitro studies. J Am Soc Nephrol 1996; 7: 350–356.
51. Brunnger M, Hulter HN, Krapf R. Effect of chronic metabolic acidosis on thyroid hormone homeostasis in humans. Am J Physiol 1997; 272: F648–F653.
52. Wiederkehr MR, Kalogiros J, Krapf R. Correction of metabolic acidosis improves thyroid and growth hormone axes in haemodialysis patients. Nephrol Dial Transplant 2004; 19: 1190–1197.
53. Gadola L, Noboa O, Marquez MN et al. Calcium citrate ameliorates the progression of chronic renal injury. Kidney Int 2004; 65: 1224–1230.
54. Shah SN, Abramowitz M, Hostetter TH et al. Serum bicarbonate levels and the progression of kidney disease: a cohort study. Am J Kidney Dis 2009; 54: 270–277.
55. de Brito-Ashurst I, Varagunam M, Raftery MJ et al. Bicarbonate supplementation slows progression of CKD and improves nutritional status. J Am Soc Nephrol 2009; 20: 2075–2084.
56. Mahajan A, Simoni J, Sheather SJ et al. Daily oral sodium bicarbonate preserves glomerular filtration rate by slowing its decline in early hypertensive nephropathy. Kidney Int 2010; 78: 303–309.
57. Phisitkul S, Khanna A, Simoni J et al. Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR. Kidney Int 2010; 77: 617–623.
58. Raphael KL, Wei G, Baird BC et al. Higher serum bicarbonate levels within the normal range are associated with better survival and renal outcomes in African Americans. Kidney Int 2010; 79: 356–362.
59. Kovesdy CP, Anderson JE, Kalantar-Zadeh K. Association of serum bicarbonate levels with mortality in patients with non-dialysis-dependent CKD Nephrol Dial Transplant 2009; 24: 1232–1237.
60. Navaneethan SD, Schold JD, Arrigain S et al. Serum Bicarbonate and Mortality in Stage 3 and 4 Chronic Kidney Disease. Clin J Am Soc Nephrol 2011; 6: 2395–2402.
61. Bommer J, Locatelli F, Satayathum S et al. Association of predialysis serum bicarbonate levels with risk of mortality and hospitalisation in the Dialysis Outcome and Practice Patterns Study (DOPPS). Am J Kidney Dis 2004; 44: 661–671.
62. Lowrie EG, Lew NL. Death risk in hemodialysis patients: the predictive value of commonly measured variables and an evaluation of death rate differences between facilities. Am J Kidney Dis 1990; 15: 458–482.
63. Wu DY, Mc Allister CJ, Kilpatrick RD et al. Association between serum bicarbonate and death in hemodialysis patients: is it better to be acidotis or alkalotic? Clin J Am Soc Nephrol 2006; 1: 70–78.
64. Kang DH, Lee R, Lee HY et al. Metabolic acidosis and composite nutritional index (CNI) in CAPD patients. Clin Nephrol 2000; 53: 124–131.
65. Dumler F, Falla P, Butler R et al. Impact of peritoneal dialysis modality and acidosis on nutritional status in peritoneal dialysis patients. Adv Perit Dial 1998; 14: 205–208.
66. Szeto CC, Wong TY, Chow KM et al. Oral sodium bicarbonate for the treatement of metabolic acidosis in peritoneal dialysis patients: a randomized placebo-control trial. J Am Soc Nephrol 2003; 14: 2119–2126.
67. Goraya N, Simoni J, Jo C et al. Dietary acid reduction with fruits and vegetables or bicarbonate attenuates kidney injury in patients with a moderately reduced glomerular filtration rate due to hypertensive nephropathy. Kidney Int 2012; 81: 86–93.
68. Hrabáčková P, Mydlík M, Molčányiová A. Acidobazická rovnováha u hemodialyzovaných chorých. Vnitř Lék 2002; 10: 959–961.
69. Faller B, Marichal JF. Loss of ultrafiltration in CAPD: a role for acetate. Perit Dial Bull 1984; 4: 10–13.
70. Slingeneyer A, Mion C, Mourad G et al. Progressive sclerosing peritonitis. A late and severe complication of maintenance peritoneal dialysis. Trans Am Soc Artif Intern Organs 1983; 29: 633–636.
71. Devuyst O, Topley N, Williams JD. Morphological and functional changes in the dialysed peritoneal cavity: impact of more biocompatible solutions. Nephrol Dial Transplant 2002; 17 (Suppl 3): 12–15.
72. Williams JD, Craig KJ, Topley N. Peritoneal dialysis: changes to the structure of the peritoneal membrane and potential for biocompatible solutions. Kidney Int 2003; (84): S158–S161.
73. Jörres A, Bender TO, Finn A et al. Biocompatibility and buffers: effect of bicarbonate- buffered peritoneal dialysis fluids on peritoneal cell function. Kidney Int 1998; 54: 2184–2193.
74. Witowski J, Korybalska K, Ksiazek K et al. Peritoneal dialysis with solutions low in glucose degradation products is associated with improved biocompatibility profile toward peritoneal mesothelial cells. Nephrol Dial Transplant 2004; 19: 917–924.
75. Pajek J, Kveder R, Bren A et al. Short-term effects of new bicarbonate/lactate buffered and conventional peritoneal dialysis fluid on peritoneal and systemic inflammation in CAPD patients: a randomized controlled study. Perit Dial Int 2008; 28: 44–52.
76. Opatrná S, Pöpperlová A, Kalousová M et al. Low GDP peritoneal dialysis regimen has beneficial effect on plasma levels of proinflamatory ligands of receptor for advanced glycation end products (v tisku).
77. Filiopoulos V, Koutis I, Trompouki S et al. Lanthanum Carbonate Versus Sevelamer Hydrochloride: Improvement of Metabolic Acidosis and Hyperkalemia in Hemodialysis Patients. Ther Apher Dial 2010; 15: 20–27.
78. De Santo NG, Frangiosa A, Anastasio P et al. Sevelamer worsens metabolic acidosis in hemodialysis patients. J Nephrol 2006; 19: S108–S114.
79. Sonikian MA, Pani IT, Iliopoulos AN et al. Metabolic acidosis aggravation and hyperkalemia in hemadialys patients treated by sevelamer hydrochloride. Renal Fail 2005; 27: 143–147.
80. Roderick PJ, Willis NS, Blakeley S et al. Correction of chronic metabolic acidosis for chronic kidney disease patients. Cochrane Database of Systemic Reviews 2007; 1: CD001890.
81. National Kidney Foundation: K/DOQI Clinical Practise Guidelines for Nutrition in Chronic Renal Failure. Am J Kidney Dis 2000; 35 (Suppl 2): S1–S140.
82. National Kidney Foundation: K/DOQI Clinical Practise Guidelines for bone metabolism in Chronic kidney disease. Am J Kidney Dis 2003; 42 (Suppl 3): S1–S201.
83. Fouque D, Vennegoor M, Ter WP et al. EBPG guideline on nutrition. Nephrol Dial Transplant 2007; 22 (Suppl 2): ii45–ii87.
84. Krediet RT. 8 Nutrition in peritoneal dialysis. Nephrol Dial Transplant 2005; 20 (Suppl 9): ix28–ix33.
85. Movilli E, Zani R, Carli O et al. Correction of metabolic acidosis increases serum albumin concentrations and decreases kinetically evaluated protein intake in hemodialysis patients: A prospective study. Nephrol Dial Transplant 1998; 13: 1719–1722.
86. Verove C, Maisonneuve N, El Azouzi A et al. Effect of the correction of metabolic acidosis on nutritional status in elderly patients with chronic renal failure. J Ren Nutr 2002; 12: 224–228.
87. Brady JP, Hasbargen JA. Correction of metabolic acidosis and its effect on albumin in chronic hemodialysis patients. Am J Kidney Dis 1998; 31: 35–40.
88. Reaich D, Channon SM, Scrimgeour CM et al. Correction of acidosis in human with chronic renal failure decreases protein degradation and amino acid oxidation. Am J Physiol 1993; 265: E230–E235.
89. Stein A, Moorhouse J, Iles-Smith H et al. Role of an improvement in acid-base status and nutrition in CAPD patients. Kidney Int 1997; 52: 1089–1095.