PLOS Genetics - Číslo 5/2015


Yeast Killer Elements Hold Their Hosts Hostage
Keeping in Shape the Dogma of Mitochondrial DNA Maternal Inheritance
Trading Places—Switching Frataxin Function by a Single Amino Acid Substitution within the [Fe-S] Cluster Assembly Scaffold


The Philosophical Approach: An Interview with Ford Doolittle
The Whole of a Scientific Career: An Interview with Oliver Smithies

Research Article

Genomic Heritability: What Is It?
Triglyceride-Increasing Alleles Associated with Protection against Type-2 Diabetes
Epistasis Is a Major Determinant of the Additive Genetic Variance in
Genetic Regulation of Bone Metabolism in the Chicken: Similarities and Differences to Mammalian Systems
Minor Type IV Collagen α5 Chain Promotes Cancer Progression through Discoidin Domain Receptor-1
Downregulation of the Host Gene by miR-92 Is Essential for Neuroblast Self-Renewal in
A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite
Y Fuse? Sex Chromosome Fusions in Fishes and Reptiles
Regulation of Active DNA Demethylation by a Methyl-CpG-Binding Domain Protein in
Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape
Autoselection of Cytoplasmic Yeast Virus Like Elements Encoding Toxin/Antitoxin Systems Involves a Nuclear Barrier for Immunity Gene Expression
Genetic Architecture of Abdominal Pigmentation in
Whole Genome DNA Binding Analysis of the Bacterial Replication Initiator and Transcription Factor DnaA
The Centrosomal Linker and Microtubules Provide Dual Levels of Spatial Coordination of Centrosomes
Parp3 Negatively Regulates Immunoglobulin Class Switch Recombination
Burden Analysis of Rare Microdeletions Suggests a Strong Impact of Neurodevelopmental Genes in Genetic Generalised Epilepsies
Cell Cycle Control by the Master Regulator CtrA in
Myopathic Lamin Mutations Cause Reductive Stress and Activate the Nrf2/Keap-1 Pathway
Monoallelic Loss of the Imprinted Gene Promotes Tumor Formation in Irradiated Mice
Phylum-Level Conservation of Regulatory Information in Nematodes despite Extensive Non-coding Sequence Divergence
Clustering and Negative Feedback by Endocytosis in Planar Cell Polarity Signaling Is Modulated by Ubiquitinylation of Prickle
Dissecting the Function and Assembly of Acentriolar Microtubule Organizing Centers in Cells In Vivo
MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells
β-Catenin Signaling Biases Multipotent Lingual Epithelial Progenitors to Differentiate and Acquire Specific Taste Cell Fates
A Simple Auxin Transcriptional Response System Regulates Multiple Morphogenetic Processes in the Liverwort
Parallel Gene Expression Differences between Low and High Latitude Populations of and .
The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of
Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci
PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses
Drosophila Spaghetti and Doubletime Link the Circadian Clock and Light to Caspases, Apoptosis and Tauopathy
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a Deficient iPSC Disease Model
Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes
Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans
Natural Variation Identifies , a Universal Gene Required for Cell Proliferation and Growth at High Temperatures in
Mutations in Gene Are Associated with Predisposition to Breast Cancer
Cell Specific eQTL Analysis without Sorting Cells
Cooperative Action of Cdk1/cyclin B and SIRT1 Is Required for Mitotic Repression of rRNA Synthesis
Systemic Regulation of RAS/MAPK Signaling by the Serotonin Metabolite 5-HIAA
Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature
The Developmental Intestinal Regulator ELT-2 Controls p38-Dependent Immune Responses in Adult .
Genetic Mechanism of Human Neutrophil Antigen 2 Deficiency and Expression Variations
Feeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in
Early Lineage Priming by Trisomy of Leads to Myeloproliferation in a Down Syndrome Model
Turning into a Frataxin-Dependent Organism
Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast
Biological Significance of Photoreceptor Photocycle Length: VIVID Photocycle Governs the Dynamic VIVID-White Collar Complex Pool Mediating Photo-adaptation and Response to Changes in Light Intensity
CTXφ Replication Depends on the Histone-Like HU Protein and the UvrD Helicase
Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature
Notch Is Required in Adult Sensory Neurons for Morphological and Functional Plasticity of the Olfactory Circuit
Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by
PERK Limits Lifespan by Promoting Intestinal Stem Cell Proliferation in Response to ER Stress
Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation
Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links Loss to the Pathogenesis of Pleuropulmonary Blastoma
Auxin-Mediated Transcriptional System with a Minimal Set of Components Is Critical for Morphogenesis through the Life Cycle in
The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition
The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation
Turning into a Frataxin-Independent Organism
Promotion of Bone Morphogenetic Protein Signaling by Tetraspanins and Glycosphingolipids
Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria
The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition

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