PLOS Genetics - Číslo 5/2015

Perspective

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Yeast Killer Elements Hold Their Hosts Hostage
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Keeping in Shape the Dogma of Mitochondrial DNA Maternal Inheritance
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Trading Places—Switching Frataxin Function by a Single Amino Acid Substitution within the [Fe-S] Cluster Assembly Scaffold

Interview

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The Philosophical Approach: An Interview with Ford Doolittle
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The Whole of a Scientific Career: An Interview with Oliver Smithies

Research Article

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Genomic Heritability: What Is It?
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Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast
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Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans
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Natural Variation Identifies , a Universal Gene Required for Cell Proliferation and Growth at High Temperatures in
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Mutations in Gene Are Associated with Predisposition to Breast Cancer
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Cell Specific eQTL Analysis without Sorting Cells
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Cooperative Action of Cdk1/cyclin B and SIRT1 Is Required for Mitotic Repression of rRNA Synthesis
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Systemic Regulation of RAS/MAPK Signaling by the Serotonin Metabolite 5-HIAA
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Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature
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The Developmental Intestinal Regulator ELT-2 Controls p38-Dependent Immune Responses in Adult .
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Genetic Mechanism of Human Neutrophil Antigen 2 Deficiency and Expression Variations
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Feeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in
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Early Lineage Priming by Trisomy of Leads to Myeloproliferation in a Down Syndrome Model
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Turning into a Frataxin-Dependent Organism
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Biological Significance of Photoreceptor Photocycle Length: VIVID Photocycle Governs the Dynamic VIVID-White Collar Complex Pool Mediating Photo-adaptation and Response to Changes in Light Intensity
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Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a Deficient iPSC Disease Model
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CTXφ Replication Depends on the Histone-Like HU Protein and the UvrD Helicase
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Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature
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Notch Is Required in Adult Sensory Neurons for Morphological and Functional Plasticity of the Olfactory Circuit
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Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by
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PERK Limits Lifespan by Promoting Intestinal Stem Cell Proliferation in Response to ER Stress
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Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation
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Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links Loss to the Pathogenesis of Pleuropulmonary Blastoma
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Auxin-Mediated Transcriptional System with a Minimal Set of Components Is Critical for Morphogenesis through the Life Cycle in
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The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition
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The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation
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Turning into a Frataxin-Independent Organism
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Promotion of Bone Morphogenetic Protein Signaling by Tetraspanins and Glycosphingolipids
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Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria
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Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes
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Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
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Triglyceride-Increasing Alleles Associated with Protection against Type-2 Diabetes
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Parp3 Negatively Regulates Immunoglobulin Class Switch Recombination
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Epistasis Is a Major Determinant of the Additive Genetic Variance in
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Genetic Regulation of Bone Metabolism in the Chicken: Similarities and Differences to Mammalian Systems
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Minor Type IV Collagen α5 Chain Promotes Cancer Progression through Discoidin Domain Receptor-1
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Downregulation of the Host Gene by miR-92 Is Essential for Neuroblast Self-Renewal in
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A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite
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Y Fuse? Sex Chromosome Fusions in Fishes and Reptiles
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Regulation of Active DNA Demethylation by a Methyl-CpG-Binding Domain Protein in
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Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape
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Autoselection of Cytoplasmic Yeast Virus Like Elements Encoding Toxin/Antitoxin Systems Involves a Nuclear Barrier for Immunity Gene Expression
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Genetic Architecture of Abdominal Pigmentation in
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Whole Genome DNA Binding Analysis of the Bacterial Replication Initiator and Transcription Factor DnaA
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The Centrosomal Linker and Microtubules Provide Dual Levels of Spatial Coordination of Centrosomes
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Burden Analysis of Rare Microdeletions Suggests a Strong Impact of Neurodevelopmental Genes in Genetic Generalised Epilepsies
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Drosophila Spaghetti and Doubletime Link the Circadian Clock and Light to Caspases, Apoptosis and Tauopathy
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Cell Cycle Control by the Master Regulator CtrA in
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Myopathic Lamin Mutations Cause Reductive Stress and Activate the Nrf2/Keap-1 Pathway
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Monoallelic Loss of the Imprinted Gene Promotes Tumor Formation in Irradiated Mice
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Phylum-Level Conservation of Regulatory Information in Nematodes despite Extensive Non-coding Sequence Divergence
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Clustering and Negative Feedback by Endocytosis in Planar Cell Polarity Signaling Is Modulated by Ubiquitinylation of Prickle
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Dissecting the Function and Assembly of Acentriolar Microtubule Organizing Centers in Cells In Vivo
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MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells
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β-Catenin Signaling Biases Multipotent Lingual Epithelial Progenitors to Differentiate and Acquire Specific Taste Cell Fates
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A Simple Auxin Transcriptional Response System Regulates Multiple Morphogenetic Processes in the Liverwort
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Parallel Gene Expression Differences between Low and High Latitude Populations of and .
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The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of
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Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci
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PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses
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The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition

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