PLOS Genetics - Číslo 10/2013

Perspective

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Defending Sperm Function
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How to Choose the Right Mate
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Playing the Field: Sox10 Recruits Different Partners to Drive Central and Peripheral Myelination

Review

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A Review of Bacteria-Animal Lateral Gene Transfer May Inform Our Understanding of Diseases like Cancer

Research Article

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A Mutation in the Gene in Labrador Retrievers with Hereditary Nasal Parakeratosis (HNPK) Provides Insights into the Epigenetics of Keratinocyte Differentiation
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Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture
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Preferential Binding to Elk-1 by SLE-Associated Risk Allele Upregulates Expression
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Rad52 Sumoylation Prevents the Toxicity of Unproductive Rad51 Filaments Independently of the Anti-Recombinase Srs2
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The Serum Resistome of a Globally Disseminated Multidrug Resistant Uropathogenic Clone
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Identification of 526 Conserved Metazoan Genetic Innovations Exposes a New Role for Cofactor E-like in Neuronal Microtubule Homeostasis
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SUMO Localizes to the Central Element of Synaptonemal Complex and Is Required for the Full Synapsis of Meiotic Chromosomes in Budding Yeast
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Integrated Enrichment Analysis of Variants and Pathways in Genome-Wide Association Studies Indicates Central Role for IL-2 Signaling Genes in Type 1 Diabetes, and Cytokine Signaling Genes in Crohn's Disease
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Genome-Wide High-Resolution Mapping of UV-Induced Mitotic Recombination Events in
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Genome-Wide Analysis of Cell Type-Specific Gene Transcription during Spore Formation in
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Two Portable Recombination Enhancers Direct Donor Choice in Fission Yeast Heterochromatin
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Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates
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Yeast Tdh3 (Glyceraldehyde 3-Phosphate Dehydrogenase) Is a Sir2-Interacting Factor That Regulates Transcriptional Silencing and rDNA Recombination
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A Minimal Nitrogen Fixation Gene Cluster from sp. WLY78 Enables Expression of Active Nitrogenase in
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High Throughput Sequencing Reveals Alterations in the Recombination Signatures with Diminishing Spo11 Activity
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Eleven Candidate Susceptibility Genes for Common Familial Colorectal Cancer
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ALS-Associated Mutations Result in Compromised Alternative Splicing and Autoregulation
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A GDF5 Point Mutation Strikes Twice - Causing BDA1 and SYNS2
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Systematic Unraveling of the Unsolved Pathway of Nicotine Degradation in
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Natural Genetic Variation of Integrin Alpha L () Modulates Ischemic Brain Injury in Stroke
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Evolutionary Tuning of Protein Expression Levels of a Positively Autoregulated Two-Component System
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Evolutionary Change within a Bipotential Switch Shaped the Sperm/Oocyte Decision in Hermaphroditic Nematodes
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Limiting of the Innate Immune Response by SF3A-Dependent Control of MyD88 Alternative mRNA Splicing
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Multiple Signaling Pathways Coordinate to Induce a Threshold Response in a Chordate Embryo
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Distinct Regulatory Mechanisms Act to Establish and Maintain Pax3 Expression in the Developing Neural Tube
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Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic
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Mismatch Repair Genes and Modify CAG Instability in Huntington's Disease Mice: Genome-Wide and Candidate Approaches
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The Histone H3 K27 Methyltransferase KMT6 Regulates Development and Expression of Secondary Metabolite Gene Clusters
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Hsp70-Hsp40 Chaperone Complex Functions in Controlling Polarized Growth by Repressing Hsf1-Driven Heat Stress-Associated Transcription
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Function and Evolution of DNA Methylation in
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Stimulation of mTORC1 with L-leucine Rescues Defects Associated with Roberts Syndrome
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Robust Demographic Inference from Genomic and SNP Data
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A Reversible Histone H3 Acetylation Cooperates with Mismatch Repair and Replicative Polymerases in Maintaining Genome Stability
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Conserved Translatome Remodeling in Nematode Species Executing a Shared Developmental Transition
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Condensin II Subunit dCAP-D3 Restricts Retrotransposon Mobilization in Somatic Cells
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A Novel Actin mRNA Splice Variant Regulates ACTG1 Expression
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Tracking Proliferative History in Lymphocyte Development with Cre-Mediated Sister Chromatid Recombination
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Correlated Occurrence and Bypass of Frame-Shifting Insertion-Deletions (InDels) to Give Functional Proteins
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Chimeric Protein Complexes in Hybrid Species Generate Novel Phenotypes
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Loss of miR-10a Activates and Collaborates with Activated Wnt Signaling in Inducing Intestinal Neoplasia in Female Mice
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Both Rare and Copy Number Variants Are Prevalent in Agenesis of the Corpus Callosum but Not in Cerebellar Hypoplasia or Polymicrogyria
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Reverse PCA, a Systematic Approach for Identifying Genes Important for the Physical Interaction between Protein Pairs
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Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice
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Genome-Wide and Cell-Specific Epigenetic Analysis Challenges the Role of Polycomb in Spermatogenesis
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Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling Pathway
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Cooperation between RUNX1-ETO9a and Novel Transcriptional Partner KLF6 in Upregulation of in Acute Myeloid Leukemia
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Mobility of the Native Conjugative Plasmid pLS20 Is Regulated by Intercellular Signaling
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FliZ Is a Global Regulatory Protein Affecting the Expression of Flagellar and Virulence Genes in Individual Bacterial Cells
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Specific Tandem Repeats Are Sufficient for Paramutation-Induced Trans-Generational Silencing
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Dominant Mutations in Identify the Mlh1-Pms1 Endonuclease Active Site and an Exonuclease 1-Independent Mismatch Repair Pathway
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Multiple bHLH Proteins form Heterodimers to Mediate CRY2-Dependent Regulation of Flowering-Time in
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The Insulator Homie Promotes Expression and Protects the Adjacent Gene from Repression by Polycomb Spreading
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Human Intellectual Disability Genes Form Conserved Functional Modules in
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Coordination of Cell Proliferation and Cell Fate Determination by CES-1 Snail
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ORFs in Drosophila Are Important to Organismal Fitness and Evolved Rapidly from Previously Non-coding Sequences
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Different Roles of Eukaryotic MutS and MutL Complexes in Repair of Small Insertion and Deletion Loops in Yeast
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The Spore Differentiation Pathway in the Enteric Pathogen
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Acceleration of the Glycolytic Flux by Steroid Receptor Coactivator-2 Is Essential for Endometrial Decidualization
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The Human Nuclear Poly(A)-Binding Protein Promotes RNA Hyperadenylation and Decay
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Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish
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Xbp1 Directs Global Repression of Budding Yeast Transcription during the Transition to Quiescence and Is Important for the Longevity and Reversibility of the Quiescent State
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The Integrator Complex Subunit 6 (Ints6) Confines the Dorsal Organizer in Vertebrate Embryogenesis
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Incorporating Motif Analysis into Gene Co-expression Networks Reveals Novel Modular Expression Pattern and New Signaling Pathways
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The Bacterial Response Regulator ArcA Uses a Diverse Binding Site Architecture to Regulate Carbon Oxidation Globally
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Direct Monitoring of the Strand Passage Reaction of DNA Topoisomerase II Triggers Checkpoint Activation
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Transcription Termination and Chimeric RNA Formation Controlled by FPA

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