PLOS Genetics - Číslo 6/2012

Perspective

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Rumors of Its Disassembly Have Been Greatly Exaggerated: The Secret Life of the Synaptonemal Complex at the Centromeres
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Mimetic Butterflies Introgress to Impress
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Tipping the Balance in the Powerhouse of the Cell to “Protect” Colorectal Cancer
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Found: The Elusive ANTAR Transcription Antiterminator

Research Article

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Selection-Driven Gene Loss in Bacteria
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Gene Expression Profiles in Parkinson Disease Prefrontal Cortex Implicate and Genes under Its Transcriptional Regulation
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The NSL Complex Regulates Housekeeping Genes in
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Attenuation of Notch and Hedgehog Signaling Is Required for Fate Specification in the Spinal Cord
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Dual-Level Regulation of ACC Synthase Activity by MPK3/MPK6 Cascade and Its Downstream WRKY Transcription Factor during Ethylene Induction in Arabidopsis
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Genome-Wide Functional Profiling Identifies Genes and Processes Important for Zinc-Limited Growth of
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Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia
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MicroRNA93 Regulates Proliferation and Differentiation of Normal and Malignant Breast Stem Cells
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Phylogenomic Analysis Reveals Dynamic Evolutionary History of the Drosophila Heterochromatin Protein 1 (HP1) Gene Family
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The Mutation in Chickens Constitutes a Structural Rearrangement Causing Both Altered Comb Morphology and Defective Sperm Motility
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Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases
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Polymorphisms in the Mitochondrial Ribosome Recycling Factor Compromise Cell Respiratory Function and Increase Atorvastatin Toxicity
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Global Regulatory Functions of the Endoribonuclease III in Gene Expression
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Genetic Variants on Chromosome 1q41 Influence Ocular Axial Length and High Myopia
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Extensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection
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The Regulatory Network of Natural Competence and Transformation of
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Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants
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Quantifying the Adaptive Potential of an Antibiotic Resistance Enzyme
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Divergence of the Yeast Transcription Factor Affects Sulfite Resistance
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The Histone Demethylase Jhdm1a Regulates Hepatic Gluconeogenesis
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RNA Methylation by the MIS Complex Regulates a Cell Fate Decision in Yeast
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Rare Copy Number Variants Observed in Hereditary Breast Cancer Cases Disrupt Genes in Estrogen Signaling and Tumor Suppression Network
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Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2
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A Mutation Links a Canine Progressive Early-Onset Cerebellar Ataxia to the Endoplasmic Reticulum–Associated Protein Degradation (ERAD) Machinery
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The Mechanism for RNA Recognition by ANTAR Regulators of Gene Expression
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Is a Key Regulator of Pancreaticobiliary Ductal System Development
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Gustatory Perception and Fat Body Energy Metabolism Are Jointly Affected by Vitellogenin and Juvenile Hormone in Honey Bees
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Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer
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Incompatibility and Competitive Exclusion of Genomic Segments between Sibling Species
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Parallel Evolution of Auditory Genes for Echolocation in Bats and Toothed Whales
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Diverse CRISPRs Evolving in Human Microbiomes
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The Rad4 ATR-Activation Domain Functions in G1/S Phase in a Chromatin-Dependent Manner
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Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains
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Uracil-Containing DNA in : Stability, Stage-Specific Accumulation, and Developmental Involvement
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Fuzzy Tandem Repeats Containing p53 Response Elements May Define Species-Specific p53 Target Genes
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Adaptive Introgression across Species Boundaries in Butterflies
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G Protein Activation without a GEF in the Plant Kingdom
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Synaptonemal Complex Components Persist at Centromeres and Are Required for Homologous Centromere Pairing in Mouse Spermatocytes
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An Engineering Approach to Extending Lifespan in
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Effects of Histone H3 Depletion on Nucleosome Occupancy and Position in
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The CCR4-NOT Complex Is Implicated in the Viability of Aneuploid Yeasts
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Patterns of Evolutionary Conservation of Essential Genes Correlate with Their Compensability
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Interplay between Synaptonemal Complex, Homologous Recombination, and Centromeres during Mammalian Meiosis
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Preferential Genome Targeting of the CBP Co-Activator by Rel and Smad Proteins in Early Embryos
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A Mouse Model of Acrodermatitis Enteropathica: Loss of Intestine Zinc Transporter ZIP4 (Slc39a4) Disrupts the Stem Cell Niche and Intestine Integrity
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Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2
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Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk Analysis
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Cohesin Proteins Promote Ribosomal RNA Production and Protein Translation in Yeast and Human Cells
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TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends
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Stimulation of Host Immune Defenses by a Small Molecule Protects from Bacterial Infection
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A Broad Requirement for TLS Polymerases η and κ, and Interacting Sumoylation and Nuclear Pore Proteins, in Lesion Bypass during Embryogenesis
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Genome-Wide Identification of Ampicillin Resistance Determinants in
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Limits to the Rate of Adaptive Substitution in Sexual Populations

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