PLOS Genetics - Číslo 11/2014

Formal Comment

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Establishing a Multidisciplinary Context for Modeling 3D Facial Shape from DNA
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Let's Face It—Complex Traits Are Just Not That Simple
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Glutamate Receptor Gene , Coffee, and Parkinson Disease
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Lack of Replication of the -by-Coffee Interaction in Parkinson Disease

Review

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Regularized Machine Learning in the Genetic Prediction of Complex Traits

Interview

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The Ethics of Our Inquiry: An Interview with Hank Greely

Research Article

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RNA Processing Factors Swd2.2 and Sen1 Antagonize RNA Pol III-Dependent Transcription and the Localization of Condensin at Pol III Genes
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Evolution of DNA Methylation Patterns in the Brassicaceae is Driven by Differences in Genome Organization
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Phylogenetically Driven Sequencing of Extremely Halophilic Archaea Reveals Strategies for Static and Dynamic Osmo-response
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Natural Polymorphisms in Human APOBEC3H and HIV-1 Vif Combine in Primary T Lymphocytes to Affect Viral G-to-A Mutation Levels and Infectivity
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A Germline Polymorphism of Thymine DNA Glycosylase Induces Genomic Instability and Cellular Transformation
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Heat-Induced Release of Epigenetic Silencing Reveals the Concealed Role of an Imprinted Plant Gene
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ATPase-Independent Type-III Protein Secretion in
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p53- and ERK7-Dependent Ribosome Surveillance Response Regulates Insulin-Like Peptide Secretion
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The Complex I Subunit Selectively Rescues Mutants through a Mechanism Independent of Mitophagy
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Regulation of mRNA Abundance by Polypyrimidine Tract-Binding Protein-Controlled Alternate 5′ Splice Site Choice
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The Red Queen Model of Recombination Hotspots Evolution in the Light of Archaic and Modern Human Genomes
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Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation
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Rad59-Facilitated Acquisition of Y′ Elements by Short Telomeres Delays the Onset of Senescence
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A Functional Portrait of Med7 and the Mediator Complex in
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Systematic Analysis of the Role of RNA-Binding Proteins in the Regulation of RNA Stability
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ARTIST: High-Resolution Genome-Wide Assessment of Fitness Using Transposon-Insertion Sequencing
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Genomic Evidence of Rapid and Stable Adaptive Oscillations over Seasonal Time Scales in Drosophila
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Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets
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Functional Diversity of Carbohydrate-Active Enzymes Enabling a Bacterium to Ferment Plant Biomass
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GPA: A Statistical Approach to Prioritizing GWAS Results by Integrating Pleiotropy and Annotation
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Inversion of the Chromosomal Region between Two Mating Type Loci Switches the Mating Type in
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The Protein -glucosyltransferase Rumi Modifies Eyes Shut to Promote Rhabdomere Separation in
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A Thermolabile Aldolase A Mutant Causes Fever-Induced Recurrent Rhabdomyolysis without Hemolytic Anemia
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The Role of Regulatory Evolution in Maize Domestication
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Stress Granule-Defective Mutants Deregulate Stress Responsive Transcripts
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24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex
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Pseudoautosomal Region 1 Length Polymorphism in the Human Population
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Fungal Communication Requires the MAK-2 Pathway Elements STE-20 and RAS-2, the NRC-1 Adapter STE-50 and the MAP Kinase Scaffold HAM-5
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The COP9 Signalosome Converts Temporal Hormone Signaling to Spatial Restriction on Neural Competence
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The Talin Head Domain Reinforces Integrin-Mediated Adhesion by Promoting Adhesion Complex Stability and Clustering
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An RNA-Seq Screen of the Antenna Identifies a Transporter Necessary for Ammonia Detection
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Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association
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Coordinate Regulation of Stem Cell Competition by Slit-Robo and JAK-STAT Signaling in the Testis
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Genetic Analysis of a Novel Tubulin Mutation That Redirects Synaptic Vesicle Targeting and Causes Neurite Degeneration in
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A Systems Genetics Approach Identifies , , and as Novel Aggressive Prostate Cancer Susceptibility Genes
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Three RNA Binding Proteins Form a Complex to Promote Differentiation of Germline Stem Cell Lineage in
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Approximation to the Distribution of Fitness Effects across Functional Categories in Human Segregating Polymorphisms
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The CSN/COP9 Signalosome Regulates Synaptonemal Complex Assembly during Meiotic Prophase I of
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SAS-1 Is a C2 Domain Protein Critical for Centriole Integrity in
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HAM-5 Functions As a MAP Kinase Scaffold during Cell Fusion in

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