PLOS Genetics - Číslo 12/2013


Stressing the Importance of CHOP in Liver Cancer
The AmAZI1ng Roles of Centriolar Satellites during Development
Flies Get a Head Start on Meiosis
And Baby Makes Three: Genomic Imprinting in Plant Embryos
Bugs in Transition: The Dynamic World of in Insects

Deep Reads

Recommendations from Jane Gitschier's Bookshelf


Cohesinopathies of a Feather Flock Together

Research Article

Defining the Role of ATP Hydrolysis in Mitotic Segregation of Bacterial Plasmids
Synaptonemal Complex Components Promote Centromere Pairing in Pre-meiotic Germ Cells
Genetic Recombination Is Targeted towards Gene Promoter Regions in Dogs
Parathyroid-Specific Deletion of Unravels a Novel Calcineurin-Dependent FGF23 Signaling Pathway That Regulates PTH Secretion
MAN1B1 Deficiency: An Unexpected CDG-II
Phosphate Flow between Hybrid Histidine Kinases CheA and CheS Controls Cyst Formation
Basolateral Mg Extrusion via CNNM4 Mediates Transcellular Mg Transport across Epithelia: A Mouse Model
Truncation of Unsilences Paternal and Ameliorates Behavioral Defects in the Angelman Syndrome Mouse Model
Autozygome Sequencing Expands the Horizon of Human Knockout Research and Provides Novel Insights into Human Phenotypic Variation
Huntington's Disease Induced Cardiac Amyloidosis Is Reversed by Modulating Protein Folding and Oxidative Stress Pathways in the Heart
Low Frequency Variants, Collapsed Based on Biological Knowledge, Uncover Complexity of Population Stratification in 1000 Genomes Project Data
Targeted Ablation of and in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis
Genomic Imprinting in the Embryo Is Partly Regulated by PRC2
Binary Cell Fate Decisions and Fate Transformation in the Larval Eye
The Stress-Regulated Transcription Factor CHOP Promotes Hepatic Inflammatory Gene Expression, Fibrosis, and Oncogenesis
A Global RNAi Screen Identifies a Key Role of Ceramide Phosphoethanolamine for Glial Ensheathment of Axons
Functional Analysis of the Interdependence between DNA Uptake Sequence and Its Cognate ComP Receptor during Natural Transformation in Species
Cross-Modulation of Homeostatic Responses to Temperature, Oxygen and Carbon Dioxide in
Alcohol-Induced Histone Acetylation Reveals a Gene Network Involved in Alcohol Tolerance
Molecular Characterization of Host-Specific Biofilm Formation in a Vertebrate Gut Symbiont
CRIS—A Novel cAMP-Binding Protein Controlling Spermiogenesis and the Development of Flagellar Bending
Dual Regulation of the Mitotic Exit Network (MEN) by PP2A-Cdc55 Phosphatase
Expanding the Marine Virosphere Using Metagenomics
Detection of Slipped-DNAs at the Trinucleotide Repeats of the Myotonic Dystrophy Type I Disease Locus in Patient Tissues
Interaction between and during Mammalian Jaw Patterning and in the Pathogenesis of Syngnathia
Mutations in the UQCC1-Interacting Protein, UQCC2, Cause Human Complex III Deficiency Associated with Perturbed Cytochrome Protein Expression
Reactivation of Chromosomally Integrated Human Herpesvirus-6 by Telomeric Circle Formation
Anoxia-Reoxygenation Regulates Mitochondrial Dynamics through the Hypoxia Response Pathway, SKN-1/Nrf, and Stomatin-Like Protein STL-1/SLP-2
The Midline Protein Regulates Axon Guidance by Blocking the Reiteration of Neuroblast Rows within the Drosophila Ventral Nerve Cord
Tomato Yield Heterosis Is Triggered by a Dosage Sensitivity of the Florigen Pathway That Fine-Tunes Shoot Architecture
Selection on Plant Male Function Genes Identifies Candidates for Reproductive Isolation of Yellow Monkeyflowers
Role of Tomato Lipoxygenase D in Wound-Induced Jasmonate Biosynthesis and Plant Immunity to Insect Herbivores
Meiotic Cohesin SMC1β Provides Prophase I Centromeric Cohesion and Is Required for Multiple Synapsis-Associated Functions
Identification of Sphingolipid Metabolites That Induce Obesity via Misregulation of Appetite, Caloric Intake and Fat Storage in
Genome-Wide Screen Reveals Replication Pathway for Quasi-Palindrome Fragility Dependent on Homologous Recombination
Histone Methylation Restrains the Expression of Subtype-Specific Genes during Terminal Neuronal Differentiation in
A Novel Intergenic ETnII-β Insertion Mutation Causes Multiple Malformations in Mice
The NuRD Chromatin-Remodeling Enzyme CHD4 Promotes Embryonic Vascular Integrity by Transcriptionally Regulating Extracellular Matrix Proteolysis
A Domesticated Transposase Interacts with Heterochromatin and Catalyzes Reproducible DNA Elimination in
Acute Versus Chronic Loss of Mammalian Results in Distinct Ciliary Phenotypes
MBD3 Localizes at Promoters, Gene Bodies and Enhancers of Active Genes
Positive and Negative Regulation of Gli Activity by Kif7 in the Zebrafish Embryo
A Hereditary Spastic Paraplegia Mouse Model Supports a Role of ZFYVE26/SPASTIZIN for the Endolysosomal System
The CCR4-NOT Complex Mediates Deadenylation and Degradation of Stem Cell mRNAs and Promotes Planarian Stem Cell Differentiation
Reconstructing Native American Migrations from Whole-Genome and Whole-Exome Data
Contributions of Protein-Coding and Regulatory Change to Adaptive Molecular Evolution in Murid Rodents
Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia
A -Acting Protein Effect Causes Severe Eye Malformation in the Mouse
Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of Genes in Developing Limbs
Germline Progenitors Escape the Widespread Phenomenon of Homolog Pairing during Development
Transcription Factor Occupancy Can Mediate Active Turnover of DNA Methylation at Regulatory Regions
Somatic mtDNA Mutation Spectra in the Aging Human Putamen
ESCRT-I Mediates FLS2 Endosomal Sorting and Plant Immunity
Ethylene Promotes Hypocotyl Growth and HY5 Degradation by Enhancing the Movement of COP1 to the Nucleus in the Light
The PAF Complex and Prf1/Rtf1 Delineate Distinct Cdk9-Dependent Pathways Regulating Transcription Elongation in Fission Yeast
Dual Regulation of Gene Expression Mediated by Extended MAPK Activation and Salicylic Acid Contributes to Robust Innate Immunity in
Quantifying Missing Heritability at Known GWAS Loci
Smc5/6-Mms21 Prevents and Eliminates Inappropriate Recombination Intermediates in Meiosis
Smc5/6 Coordinates Formation and Resolution of Joint Molecules with Chromosome Morphology to Ensure Meiotic Divisions
Tay Bridge Is a Negative Regulator of EGFR Signalling and Interacts with Erk and Mkp3 in the Wing
Meiotic Crossover Control by Concerted Action of Rad51-Dmc1 in Homolog Template Bias and Robust Homeostatic Regulation
Active Transport and Diffusion Barriers Restrict Joubert Syndrome-Associated ARL13B/ARL-13 to an Inv-like Ciliary Membrane Subdomain
An Regulatory Circuit Modulates /Wnt Signaling and Determines the Size of the Midbrain Dopaminergic Progenitor Pool
Variants Induce Differential Protection to Viruses in : A Phenotypic and Phylogenomic Analysis
Base Pairing Interaction between 5′- and 3′-UTRs Controls mRNA Translation in
Evidence That Masking of Synapsis Imperfections Counterbalances Quality Control to Promote Efficient Meiosis
Insulin/IGF-Regulated Size Scaling of Neuroendocrine Cells Expressing the bHLH Transcription Factor in
Sumoylated NHR-25/NR5A Regulates Cell Fate during Vulval Development
TATN-1 Mutations Reveal a Novel Role for Tyrosine as a Metabolic Signal That Influences Developmental Decisions and Longevity in

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