PLOS Genetics - Číslo 12/2013

Perspective

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Stressing the Importance of CHOP in Liver Cancer
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The AmAZI1ng Roles of Centriolar Satellites during Development
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Flies Get a Head Start on Meiosis
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And Baby Makes Three: Genomic Imprinting in Plant Embryos
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Bugs in Transition: The Dynamic World of in Insects

Deep Reads

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Recommendations from Jane Gitschier's Bookshelf

Review

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Cohesinopathies of a Feather Flock Together

Research Article

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Defining the Role of ATP Hydrolysis in Mitotic Segregation of Bacterial Plasmids
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Somatic mtDNA Mutation Spectra in the Aging Human Putamen
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The NuRD Chromatin-Remodeling Enzyme CHD4 Promotes Embryonic Vascular Integrity by Transcriptionally Regulating Extracellular Matrix Proteolysis
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A Domesticated Transposase Interacts with Heterochromatin and Catalyzes Reproducible DNA Elimination in
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Acute Versus Chronic Loss of Mammalian Results in Distinct Ciliary Phenotypes
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MBD3 Localizes at Promoters, Gene Bodies and Enhancers of Active Genes
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Positive and Negative Regulation of Gli Activity by Kif7 in the Zebrafish Embryo
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A Hereditary Spastic Paraplegia Mouse Model Supports a Role of ZFYVE26/SPASTIZIN for the Endolysosomal System
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The CCR4-NOT Complex Mediates Deadenylation and Degradation of Stem Cell mRNAs and Promotes Planarian Stem Cell Differentiation
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Reconstructing Native American Migrations from Whole-Genome and Whole-Exome Data
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Contributions of Protein-Coding and Regulatory Change to Adaptive Molecular Evolution in Murid Rodents
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Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia
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A -Acting Protein Effect Causes Severe Eye Malformation in the Mouse
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Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of Genes in Developing Limbs
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Germline Progenitors Escape the Widespread Phenomenon of Homolog Pairing during Development
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Transcription Factor Occupancy Can Mediate Active Turnover of DNA Methylation at Regulatory Regions
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ESCRT-I Mediates FLS2 Endosomal Sorting and Plant Immunity
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Histone Methylation Restrains the Expression of Subtype-Specific Genes during Terminal Neuronal Differentiation in
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Active Transport and Diffusion Barriers Restrict Joubert Syndrome-Associated ARL13B/ARL-13 to an Inv-like Ciliary Membrane Subdomain
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Sumoylated NHR-25/NR5A Regulates Cell Fate during Vulval Development
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Insulin/IGF-Regulated Size Scaling of Neuroendocrine Cells Expressing the bHLH Transcription Factor in
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Evidence That Masking of Synapsis Imperfections Counterbalances Quality Control to Promote Efficient Meiosis
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Base Pairing Interaction between 5′- and 3′-UTRs Controls mRNA Translation in
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Variants Induce Differential Protection to Viruses in : A Phenotypic and Phylogenomic Analysis
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An Regulatory Circuit Modulates /Wnt Signaling and Determines the Size of the Midbrain Dopaminergic Progenitor Pool
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Meiotic Crossover Control by Concerted Action of Rad51-Dmc1 in Homolog Template Bias and Robust Homeostatic Regulation
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Ethylene Promotes Hypocotyl Growth and HY5 Degradation by Enhancing the Movement of COP1 to the Nucleus in the Light
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Tay Bridge Is a Negative Regulator of EGFR Signalling and Interacts with Erk and Mkp3 in the Wing
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Smc5/6 Coordinates Formation and Resolution of Joint Molecules with Chromosome Morphology to Ensure Meiotic Divisions
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Smc5/6-Mms21 Prevents and Eliminates Inappropriate Recombination Intermediates in Meiosis
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Quantifying Missing Heritability at Known GWAS Loci
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Dual Regulation of Gene Expression Mediated by Extended MAPK Activation and Salicylic Acid Contributes to Robust Innate Immunity in
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The PAF Complex and Prf1/Rtf1 Delineate Distinct Cdk9-Dependent Pathways Regulating Transcription Elongation in Fission Yeast
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A Novel Intergenic ETnII-β Insertion Mutation Causes Multiple Malformations in Mice
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Genome-Wide Screen Reveals Replication Pathway for Quasi-Palindrome Fragility Dependent on Homologous Recombination
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Synaptonemal Complex Components Promote Centromere Pairing in Pre-meiotic Germ Cells
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Functional Analysis of the Interdependence between DNA Uptake Sequence and Its Cognate ComP Receptor during Natural Transformation in Species
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Genetic Recombination Is Targeted towards Gene Promoter Regions in Dogs
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Parathyroid-Specific Deletion of Unravels a Novel Calcineurin-Dependent FGF23 Signaling Pathway That Regulates PTH Secretion
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MAN1B1 Deficiency: An Unexpected CDG-II
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Phosphate Flow between Hybrid Histidine Kinases CheA and CheS Controls Cyst Formation
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Basolateral Mg Extrusion via CNNM4 Mediates Transcellular Mg Transport across Epithelia: A Mouse Model
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Truncation of Unsilences Paternal and Ameliorates Behavioral Defects in the Angelman Syndrome Mouse Model
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Autozygome Sequencing Expands the Horizon of Human Knockout Research and Provides Novel Insights into Human Phenotypic Variation
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Huntington's Disease Induced Cardiac Amyloidosis Is Reversed by Modulating Protein Folding and Oxidative Stress Pathways in the Heart
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Low Frequency Variants, Collapsed Based on Biological Knowledge, Uncover Complexity of Population Stratification in 1000 Genomes Project Data
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Targeted Ablation of and in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis
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Genomic Imprinting in the Embryo Is Partly Regulated by PRC2
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Binary Cell Fate Decisions and Fate Transformation in the Larval Eye
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The Stress-Regulated Transcription Factor CHOP Promotes Hepatic Inflammatory Gene Expression, Fibrosis, and Oncogenesis
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A Global RNAi Screen Identifies a Key Role of Ceramide Phosphoethanolamine for Glial Ensheathment of Axons
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Cross-Modulation of Homeostatic Responses to Temperature, Oxygen and Carbon Dioxide in
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Identification of Sphingolipid Metabolites That Induce Obesity via Misregulation of Appetite, Caloric Intake and Fat Storage in
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Reactivation of Chromosomally Integrated Human Herpesvirus-6 by Telomeric Circle Formation
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Meiotic Cohesin SMC1β Provides Prophase I Centromeric Cohesion and Is Required for Multiple Synapsis-Associated Functions
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Role of Tomato Lipoxygenase D in Wound-Induced Jasmonate Biosynthesis and Plant Immunity to Insect Herbivores
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Selection on Plant Male Function Genes Identifies Candidates for Reproductive Isolation of Yellow Monkeyflowers
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Tomato Yield Heterosis Is Triggered by a Dosage Sensitivity of the Florigen Pathway That Fine-Tunes Shoot Architecture
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The Midline Protein Regulates Axon Guidance by Blocking the Reiteration of Neuroblast Rows within the Drosophila Ventral Nerve Cord
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Anoxia-Reoxygenation Regulates Mitochondrial Dynamics through the Hypoxia Response Pathway, SKN-1/Nrf, and Stomatin-Like Protein STL-1/SLP-2
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Mutations in the UQCC1-Interacting Protein, UQCC2, Cause Human Complex III Deficiency Associated with Perturbed Cytochrome Protein Expression
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Alcohol-Induced Histone Acetylation Reveals a Gene Network Involved in Alcohol Tolerance
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Interaction between and during Mammalian Jaw Patterning and in the Pathogenesis of Syngnathia
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Detection of Slipped-DNAs at the Trinucleotide Repeats of the Myotonic Dystrophy Type I Disease Locus in Patient Tissues
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Expanding the Marine Virosphere Using Metagenomics
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Dual Regulation of the Mitotic Exit Network (MEN) by PP2A-Cdc55 Phosphatase
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CRIS—A Novel cAMP-Binding Protein Controlling Spermiogenesis and the Development of Flagellar Bending
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Molecular Characterization of Host-Specific Biofilm Formation in a Vertebrate Gut Symbiont
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TATN-1 Mutations Reveal a Novel Role for Tyrosine as a Metabolic Signal That Influences Developmental Decisions and Longevity in

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