ScreenPro FH – projekt v oblasti screeningu zaměřený na familiární hypercholesterolemii ve střední, jižní a východní Evropě: odůvodnění a záměr


Autoři: Richard Češka 1;  György Paragh 2;  Željko Reiner 3;  Maciej Banach 4;  Lale Tokgözoğlu 5;  Andrey ;  V. Susekov 6;  Katarína Rašlová 7;  Tomáš Freiberger 8,9;  Branislav Vohnout 7,10;  Andrzej Rynkiewicz 11;  Assen Goudev 12;  Gheorghe-Andrei Dan 13;  Dan Gaiţă 14;  Belma Pojskić 15;  Ivan Pećin 3;  Meral Kayıkçıoğlu 16;  Olena Mitchenko 17;  Marat V. Ezhov 18;  Gustavs Latkovskis 19;  Žaneta Petrulionienė 20;  Zlatko Fras 21;  Nebojsa Tasić 22;  Erkin M. Mirrakhimov 23;  Tolkun Murataliev 23;  Alexander B. Shek 24;  Vladimír Tuka 1;  Alexandros D. Tselepis 25;  Elie M. Moubarak 26;  Khalid Al Rasadi 27
Působiště autorů: Paul Stradins Clinical University Hospital, Riga, Latvia ;  Third Department of Medicine – Department of Endocrinology and Metabolism of the First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic 1;  Institute of Nutrition, FOaZOS, Slovak Medical University, Bratislava, Slovakia 10;  Department of Cardiology and Cardiosurgery, Faculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, Poland 11;  Queen Giovanna University Hospital, Sofia, Bulgaria 12;  University of Medicine Carol Davila, Colentina University Hospital, Bucharest, Romania 13;  University of Medicine & Pharmacy Victor Babes, Institute of Cardiovascular Diseases, CardioPrevent Foundation Timisoara, Romania 14;  Cantonal hospital, Zenica, Bosnia and Herzegovina 15;  Cardiology Department, Ege University Medical School, Lipid Clinic, Izmir, Turkey 16;  Institute of Cardiology, AMS Ukraine Dyslipidemia Department, Kiev, Ukraine 17;  Russian Cardiology Research and Production Centre, Moscow, Russian Federation 18;  Latvian Institute of Cardiology and Regenerative Medicine, Faculty of Medicine, University of Latvia 19;  Institute of Internal Medicine, University of Debrecen Faculty of Medicine, Debrecen, Hungary 2;  Centre of Cardiology and Angiology, Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania 20;  Division of Internal Medicine, Preventive Cardiology Unit and Medical Faculty, University of Ljubljana, University Medical Centre, Ljubljana, Slovenia 21;  Cardiovascular Research Centre, Cardiovascular Institute “Dedinje”, Belgrade, Serbia 22;  National Centre of Cardiology and Therapy named after academician Mirsaid Mirrakhimov, Kyrgyz State Medical Academy naved after I. K. Akhunbaev, Bishkek, Kyrgyzstan 23;  Republican Specialized Centre of Cardiology, Tashkent, Uzbekistan 24;  Department of Chemistry, University of Ioannina, Atherothrombosis Research Centre, Ioannina, Greece 25;  LDL apheresis Centre, Dahr El Bachek Government University Hospital – DGUH, Roumieh – Lebanon 26;  College of Medicine and Health Science at Sultan Qaboos University, Sultan Qaboos University Hospital, Muscat, Oman 27;  Department of Internal Medicine, Division of Metabolic Diseases, School of Medicine University of Zagreb, University Hospital Centre Zagreb, Zagreb, Croatia 3;  Department of Hypertension, Medical University of Lodz, Lodz, Poland 4;  Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey 5;  Department of clinical Pharmacology and therapeutics, Academy for Postgraduate Education, Ministry of Health, Russian Federation 6;  Coordination Centre for Familial Hyperlipidemias, Slovak Medical University, Bratislava, Slovakia 7;  Molecular Genetics Lab, Centre for Cardiovascular Surgery and Transplantation, Brno, Czech Republic 8;  Medical Faculty, Masaryk University, Brno, Czech Republic 9
Vyšlo v časopise: Vnitř Lék 2017; 63(1): 43-48
Kategorie: Přehledné referáty

Souhrn

Familiární hypercholesterolemie (FH) je geneticky podmíněné onemocnění s velmi dobře popsaným genetickým přenosem a klinickým průběhem. I přes významný pokrok v nedávné době je familiární hypercholesterolemie dosud podceňovaná, nedostatečně diagnostikovaná a tedy i nedostatečně léčená. Jako společný rizikový faktor předčasného vzniku kardiovaskulárního onemocnění navíc představuje důležitou výzvu v oblasti zdravotní péče. Projekt ScreenPro FH je zaměřen na rozvoj mezinárodní sítě, která podpoří zkvalitňování komplexní péče – od včasného screeningu přes stanovení diagnózy až k nejmodernější léčbě familiární hypercholesterolemie ve střední, východní a jižní Evropě. Důležitým úkolem projektu je harmonizovat a sjednotit diagnostické a terapeutické přístupy v jednotlivých zúčastněných zemích, v nichž je situace v každé z nich odlišná. Země s většími zkušenostmi by měly sloužit jako vzor pro ty, které svou síť FH nyní budují.

Klíčová slova:
familiární hypercholesterolemie – screening – diagnóza – optimalizace léčby


Zdroje

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Štítky
Diabetologie Endokrinologie Interní lékařství

Článek vyšel v časopise

Vnitřní lékařství

Číslo 1

2017 Číslo 1

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