PLOS Genetics - Číslo 6/2013

Perspective

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Hooked and Cooked: A Fish Killer Genome Exposed

Interview

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How Cool Is That: An Interview with Caroline Dean

Research Article

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BMS1 Is Mutated in Aplasia Cutis Congenita
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DNA Ligase IV Supports Imprecise End Joining Independently of Its Catalytic Activity
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A Six Months Exercise Intervention Influences the Genome-wide DNA Methylation Pattern in Human Adipose Tissue
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The Gene Desert Mammary Carcinoma Susceptibility Locus Regulates Modifying Mammary Epithelial Cell Differentiation and Proliferation
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Distinct Neuroblastoma-associated Alterations of Impair Sympathetic Neuronal Differentiation in Zebrafish Models
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Mutations in Cause Autosomal Recessive Congenital Ichthyosis in Humans
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Integrated Transcriptomic and Epigenomic Analysis of Primary Human Lung Epithelial Cell Differentiation
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RSR-2, the Ortholog of Human Spliceosomal Component SRm300/SRRM2, Regulates Development by Influencing the Transcriptional Machinery
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Comparative Polygenic Analysis of Maximal Ethanol Accumulation Capacity and Tolerance to High Ethanol Levels of Cell Proliferation in Yeast
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SPO11-Independent DNA Repair Foci and Their Role in Meiotic Silencing
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Budding Yeast ATM/ATR Control Meiotic Double-Strand Break (DSB) Levels by Down-Regulating Rec114, an Essential Component of the DSB-machinery
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Comprehensive High-Resolution Analysis of the Role of an Arabidopsis Gene Family in RNA Editing
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Functional Analysis of Neuronal MicroRNAs in Dauer Formation by Combinational Genetics and Neuronal miRISC Immunoprecipitation
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Extensive Intra-Kingdom Horizontal Gene Transfer Converging on a Fungal Fructose Transporter Gene
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USF1 and hSET1A Mediated Epigenetic Modifications Regulate Lineage Differentiation and Transcription
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Heritable Change Caused by Transient Transcription Errors
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From Many, One: Genetic Control of Prolificacy during Maize Domestication
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Neuronal Target Identification Requires AHA-1-Mediated Fine-Tuning of Wnt Signaling in
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Loss of Catalytically Inactive Lipid Phosphatase Myotubularin-related Protein 12 Impairs Myotubularin Stability and Promotes Centronuclear Myopathy in Zebrafish
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H-NS Can Facilitate Specific DNA-binding by RNA Polymerase in AT-rich Gene Regulatory Regions
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Prophage Dynamics and Contributions to Pathogenic Traits
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Global DNA Hypermethylation in Down Syndrome Placenta
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Fragile DNA Motifs Trigger Mutagenesis at Distant Chromosomal Loci in
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Disturbed Local Auxin Homeostasis Enhances Cellular Anisotropy and Reveals Alternative Wiring of Auxin-ethylene Crosstalk in Seminal Roots
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Causes and Consequences of Chromatin Variation between Inbred Mice
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Genome-scale Analysis of FNR Reveals Complex Features of Transcription Factor Binding
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Distinct and Atypical Intrinsic and Extrinsic Cell Death Pathways between Photoreceptor Cell Types upon Specific Ablation of in Cone Photoreceptors
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Methylation of Histone H3 on Lysine 79 Associates with a Group of Replication Origins and Helps Limit DNA Replication Once per Cell Cycle
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Evidence for Two Different Regulatory Mechanisms Linking Replication and Segregation of Chromosome II
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High Trans-ethnic Replicability of GWAS Results Implies Common Causal Variants
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Transcriptome-Wide Mapping of 5-methylcytidine RNA Modifications in Bacteria, Archaea, and Yeast Reveals mC within Archaeal mRNAs
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Genetic Architecture of Vitamin B and Folate Levels Uncovered Applying Deeply Sequenced Large Datasets
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Juvenile Hormone and Insulin Regulate Trehalose Homeostasis in the Red Flour Beetle,
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Meiosis-Specific Stable Binding of Augmin to Acentrosomal Spindle Poles Promotes Biased Microtubule Assembly in Oocytes
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Environmental Dependence of Genetic Constraint
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H3.3-H4 Tetramer Splitting Events Feature Cell-Type Specific Enhancers
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Network Topologies and Convergent Aetiologies Arising from Deletions and Duplications Observed in Individuals with Autism
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Effectively Identifying eQTLs from Multiple Tissues by Combining Mixed Model and Meta-analytic Approaches
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Altered Splicing of the BIN1 Muscle-Specific Exon in Humans and Dogs with Highly Progressive Centronuclear Myopathy
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The NADPH Metabolic Network Regulates Human Cardiomyopathy and Reductive Stress in
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Negative Regulation of Notch Signaling by Xylose
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A Genome-Wide, Fine-Scale Map of Natural Pigmentation Variation in
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Multiplexin Promotes Heart but Not Aorta Morphogenesis by Polarized Enhancement of Slit/Robo Activity at the Heart Lumen
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Deregulation of the Protocadherin Gene Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy
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Latent Effects of Hsp90 Mutants Revealed at Reduced Expression Levels
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Impact of Natural Genetic Variation on Gene Expression Dynamics
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DeepSAGE Reveals Genetic Variants Associated with Alternative Polyadenylation and Expression of Coding and Non-coding Transcripts
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The Identification of -acting Factors That Regulate the Expression of via the Osteoarthritis Susceptibility SNP rs143383
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Pervasive Transcription of the Human Genome Produces Thousands of Previously Unidentified Long Intergenic Noncoding RNAs
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The RNA Export Factor, Nxt1, Is Required for Tissue Specific Transcriptional Regulation
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Inferring Demographic History from a Spectrum of Shared Haplotype Lengths
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Histone Acetyl Transferase 1 Is Essential for Mammalian Development, Genome Stability, and the Processing of Newly Synthesized Histones H3 and H4
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PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation
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DNA Methylation Restricts Lineage-specific Functions of Transcription Factor Gata4 during Embryonic Stem Cell Differentiation
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The Genome of : Evolution, Organization, and Expression of the Cyclosporin Biosynthetic Gene Cluster
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Distinctive Expansion of Potential Virulence Genes in the Genome of the Oomycete Fish Pathogen
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Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

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