PLOS Genetics - Číslo 1/2014

Review

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Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?
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Single Cell Genomics: Advances and Future Perspectives

Perspective

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How Much Is That in Dog Years? The Advent of Canine Population Genomics
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The Sense and Sensibility of Strand Exchange in Recombination Homeostasis
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Unwrapping Bacteria

Research Article

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DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4 T-Cell Population Structure
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A Comprehensive tRNA Deletion Library Unravels the Genetic Architecture of the tRNA Pool
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A Cell Cycle and Nutritional Checkpoint Controlling Bacterial Surface Adhesion
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Tissue Specific Roles for the Ribosome Biogenesis Factor Wdr43 in Zebrafish Development
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GATA6 Is a Crucial Regulator of Shh in the Limb Bud
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Zinc Finger Transcription Factors Displaced SREBP Proteins as the Major Sterol Regulators during Saccharomycotina Evolution
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Genomic Confirmation of Hybridisation and Recent Inbreeding in a Vector-Isolated Population
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A PNPase Dependent CRISPR System in
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A Transcription Factor Is Wound-Induced at the Planarian Midline and Required for Anterior Pole Regeneration
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E3 Ubiquitin Ligase CHIP and NBR1-Mediated Selective Autophagy Protect Additively against Proteotoxicity in Plant Stress Responses
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, a -Antisense Gene of , Encodes a Evolved Protein That Inhibits GSK3β Resulting in the Stabilization of MYCN in Human Neuroblastomas
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Meta-Analysis Identifies Gene-by-Environment Interactions as Demonstrated in a Study of 4,965 Mice
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Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci
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Genome Sequencing Highlights the Dynamic Early History of Dogs
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Down-Regulation of eIF4GII by miR-520c-3p Represses Diffuse Large B Cell Lymphoma Development
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The SPF27 Homologue Num1 Connects Splicing and Kinesin 1-Dependent Cytoplasmic Trafficking in
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High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms
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Evolutionary Rate Covariation Identifies New Members of a Protein Network Required for Female Post-Mating Responses
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Subtle Changes in Motif Positioning Cause Tissue-Specific Effects on Robustness of an Enhancer's Activity
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Age, Gender, and Cancer but Not Neurodegenerative and Cardiovascular Diseases Strongly Modulate Systemic Effect of the Apolipoprotein E4 Allele on Lifespan
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The Transcription Factor BcLTF1 Regulates Virulence and Light Responses in the Necrotrophic Plant Pathogen
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Comparative Evolutionary and Developmental Dynamics of the Cotton () Fiber Transcriptome
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A 660-Kb Deletion with Antagonistic Effects on Fertility and Milk Production Segregates at High Frequency in Nordic Red Cattle: Additional Evidence for the Common Occurrence of Balancing Selection in Livestock
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Functional Divergence and Evolutionary Turnover in Mammalian Phosphoproteomes
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Vestigialization of an Allosteric Switch: Genetic and Structural Mechanisms for the Evolution of Constitutive Activity in a Steroid Hormone Receptor
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Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response
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Variation in Genome-Wide Levels of Meiotic Recombination Is Established at the Onset of Prophase in Mammalian Males
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3′ Untranslated Regions Mediate Transcriptional Interference between Convergent Genes Both Locally and Ectopically in
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Large Inverted Duplications in the Human Genome Form via a Fold-Back Mechanism
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Genomes Reveal Evolution of Microalgal Oleaginous Traits
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AL PHD-PRC1 Complexes Promote Seed Germination through H3K4me3-to-H3K27me3 Chromatin State Switch in Repression of Seed Developmental Genes
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Notch Controls Cell Adhesion in the Drosophila Eye
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Metabolic QTL Analysis Links Chloroquine Resistance in to Impaired Hemoglobin Catabolism
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Single Nucleus Genome Sequencing Reveals High Similarity among Nuclei of an Endomycorrhizal Fungus
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C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors
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A Neurotoxic Glycerophosphocholine Impacts PtdIns-4, 5-Bisphosphate and TORC2 Signaling by Altering Ceramide Biosynthesis in Yeast
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Evidence for Mito-Nuclear and Sex-Linked Reproductive Barriers between the Hybrid Italian Sparrow and Its Parent Species
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Loss of Histone H3 Methylation at Lysine 4 Triggers Apoptosis in
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PP2A/B55 and Fcp1 Regulate Greatwall and Ensa Dephosphorylation during Mitotic Exit
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Developmental Link between Sex and Nutrition; Regulates Sex-Specific Mandible Growth via Juvenile Hormone Signaling in Stag Beetles
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Deletion of a Conserved -Element in the Locus Highlights the Role of Acute Histone Acetylation in Modulating Inducible Gene Transcription
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A Nonsense Mutation in Encoding a Nondescript Transmembrane Protein Causes Idiopathic Male Subfertility in Cattle
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How a Retrotransposon Exploits the Plant's Heat Stress Response for Its Activation
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Cell-Cycle Dependent Expression of a Translocation-Mediated Fusion Oncogene Mediates Checkpoint Adaptation in Rhabdomyosarcoma
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Defining NELF-E RNA Binding in HIV-1 and Promoter-Proximal Pause Regions
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Comprehensive Functional Annotation of 77 Prostate Cancer Risk Loci
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Bioelectric Signaling Regulates Size in Zebrafish Fins
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Loss and Recovery of Genetic Diversity in Adapting Populations of HIV
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ComEA Is Essential for the Transfer of External DNA into the Periplasm in Naturally Transformable Cells
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Genetic Models of Apoptosis-Induced Proliferation Decipher Activation of JNK and Identify a Requirement of EGFR Signaling for Tissue Regenerative Responses in
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Relationship Estimation from Whole-Genome Sequence Data
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Translation Enhancing ACA Motifs and Their Silencing by a Bacterial Small Regulatory RNA
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Differential Effects of Collagen Prolyl 3-Hydroxylation on Skeletal Tissues
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Evolution of Chloroplast Transcript Processing in and Its Chromerid Algal Relatives
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Multi-tissue Analysis of Co-expression Networks by Higher-Order Generalized Singular Value Decomposition Identifies Functionally Coherent Transcriptional Modules
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In-Vivo Quantitative Proteomics Reveals a Key Contribution of Post-Transcriptional Mechanisms to the Circadian Regulation of Liver Metabolism
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Down-Regulation of Rad51 Activity during Meiosis in Yeast Prevents Competition with Dmc1 for Repair of Double-Strand Breaks
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The SET Domain Proteins SUVH2 and SUVH9 Are Required for Pol V Occupancy at RNA-Directed DNA Methylation Loci
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Affects Plant Architecture by Regulating Local Auxin Biosynthesis
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p53 and TAp63 Promote Keratinocyte Proliferation and Differentiation in Breeding Tubercles of the Zebrafish
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The Acid Phosphatase-Encoding Gene Contributes to Soybean Tolerance to Low-Phosphorus Stress
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The Candidate Splicing Factor Sfswap Regulates Growth and Patterning of Inner Ear Sensory Organs
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Natural Selection Reduced Diversity on Human Y Chromosomes
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A Chaperone-Assisted Degradation Pathway Targets Kinetochore Proteins to Ensure Genome Stability
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WNT7B Promotes Bone Formation in part through mTORC1
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Molecular Specificity, Convergence and Constraint Shape Adaptive Evolution in Nutrient-Poor Environments
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Intrasubtype Reassortments Cause Adaptive Amino Acid Replacements in H3N2 Influenza Genes
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Regulation of Synaptic /Neuroligin Abundance by the /Nrf Stress Response Pathway Protects against Oxidative Stress
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FGFR1-Frs2/3 Signalling Maintains Sensory Progenitors during Inner Ear Hair Cell Formation
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A Genome-Wide Screen for Bacterial Envelope Biogenesis Mutants Identifies a Novel Factor Involved in Cell Wall Precursor Metabolism
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New MicroRNAs in —Birth, Death and Cycles of Adaptive Evolution
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Crossover Patterning by the Beam-Film Model: Analysis and Implications

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