PLOS Genetics - Číslo 1/2014


Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?
Single Cell Genomics: Advances and Future Perspectives


How Much Is That in Dog Years? The Advent of Canine Population Genomics
The Sense and Sensibility of Strand Exchange in Recombination Homeostasis
Unwrapping Bacteria

Research Article

DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4 T-Cell Population Structure
Evidence for Mito-Nuclear and Sex-Linked Reproductive Barriers between the Hybrid Italian Sparrow and Its Parent Species
Translation Enhancing ACA Motifs and Their Silencing by a Bacterial Small Regulatory RNA
Relationship Estimation from Whole-Genome Sequence Data
Genetic Models of Apoptosis-Induced Proliferation Decipher Activation of JNK and Identify a Requirement of EGFR Signaling for Tissue Regenerative Responses in
ComEA Is Essential for the Transfer of External DNA into the Periplasm in Naturally Transformable Cells
Loss and Recovery of Genetic Diversity in Adapting Populations of HIV
Bioelectric Signaling Regulates Size in Zebrafish Fins
Defining NELF-E RNA Binding in HIV-1 and Promoter-Proximal Pause Regions
Loss of Histone H3 Methylation at Lysine 4 Triggers Apoptosis in
Cell-Cycle Dependent Expression of a Translocation-Mediated Fusion Oncogene Mediates Checkpoint Adaptation in Rhabdomyosarcoma
How a Retrotransposon Exploits the Plant's Heat Stress Response for Its Activation
A Nonsense Mutation in Encoding a Nondescript Transmembrane Protein Causes Idiopathic Male Subfertility in Cattle
Deletion of a Conserved -Element in the Locus Highlights the Role of Acute Histone Acetylation in Modulating Inducible Gene Transcription
Developmental Link between Sex and Nutrition; Regulates Sex-Specific Mandible Growth via Juvenile Hormone Signaling in Stag Beetles
PP2A/B55 and Fcp1 Regulate Greatwall and Ensa Dephosphorylation during Mitotic Exit
Differential Effects of Collagen Prolyl 3-Hydroxylation on Skeletal Tissues
Comprehensive Functional Annotation of 77 Prostate Cancer Risk Loci
Evolution of Chloroplast Transcript Processing in and Its Chromerid Algal Relatives
A Chaperone-Assisted Degradation Pathway Targets Kinetochore Proteins to Ensure Genome Stability
New MicroRNAs in —Birth, Death and Cycles of Adaptive Evolution
A Genome-Wide Screen for Bacterial Envelope Biogenesis Mutants Identifies a Novel Factor Involved in Cell Wall Precursor Metabolism
FGFR1-Frs2/3 Signalling Maintains Sensory Progenitors during Inner Ear Hair Cell Formation
Regulation of Synaptic /Neuroligin Abundance by the /Nrf Stress Response Pathway Protects against Oxidative Stress
Intrasubtype Reassortments Cause Adaptive Amino Acid Replacements in H3N2 Influenza Genes
Molecular Specificity, Convergence and Constraint Shape Adaptive Evolution in Nutrient-Poor Environments
WNT7B Promotes Bone Formation in part through mTORC1
Natural Selection Reduced Diversity on Human Y Chromosomes
In-Vivo Quantitative Proteomics Reveals a Key Contribution of Post-Transcriptional Mechanisms to the Circadian Regulation of Liver Metabolism
The Candidate Splicing Factor Sfswap Regulates Growth and Patterning of Inner Ear Sensory Organs
The Acid Phosphatase-Encoding Gene Contributes to Soybean Tolerance to Low-Phosphorus Stress
p53 and TAp63 Promote Keratinocyte Proliferation and Differentiation in Breeding Tubercles of the Zebrafish
Affects Plant Architecture by Regulating Local Auxin Biosynthesis
The SET Domain Proteins SUVH2 and SUVH9 Are Required for Pol V Occupancy at RNA-Directed DNA Methylation Loci
Down-Regulation of Rad51 Activity during Meiosis in Yeast Prevents Competition with Dmc1 for Repair of Double-Strand Breaks
Multi-tissue Analysis of Co-expression Networks by Higher-Order Generalized Singular Value Decomposition Identifies Functionally Coherent Transcriptional Modules
A Neurotoxic Glycerophosphocholine Impacts PtdIns-4, 5-Bisphosphate and TORC2 Signaling by Altering Ceramide Biosynthesis in Yeast
Subtle Changes in Motif Positioning Cause Tissue-Specific Effects on Robustness of an Enhancer's Activity
C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors
The SPF27 Homologue Num1 Connects Splicing and Kinesin 1-Dependent Cytoplasmic Trafficking in
Down-Regulation of eIF4GII by miR-520c-3p Represses Diffuse Large B Cell Lymphoma Development
Genome Sequencing Highlights the Dynamic Early History of Dogs
Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci
Meta-Analysis Identifies Gene-by-Environment Interactions as Demonstrated in a Study of 4,965 Mice
, a -Antisense Gene of , Encodes a Evolved Protein That Inhibits GSK3β Resulting in the Stabilization of MYCN in Human Neuroblastomas
A Transcription Factor Is Wound-Induced at the Planarian Midline and Required for Anterior Pole Regeneration
A Comprehensive tRNA Deletion Library Unravels the Genetic Architecture of the tRNA Pool
A PNPase Dependent CRISPR System in
Genomic Confirmation of Hybridisation and Recent Inbreeding in a Vector-Isolated Population
Zinc Finger Transcription Factors Displaced SREBP Proteins as the Major Sterol Regulators during Saccharomycotina Evolution
GATA6 Is a Crucial Regulator of Shh in the Limb Bud
Tissue Specific Roles for the Ribosome Biogenesis Factor Wdr43 in Zebrafish Development
A Cell Cycle and Nutritional Checkpoint Controlling Bacterial Surface Adhesion
High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms
E3 Ubiquitin Ligase CHIP and NBR1-Mediated Selective Autophagy Protect Additively against Proteotoxicity in Plant Stress Responses
Evolutionary Rate Covariation Identifies New Members of a Protein Network Required for Female Post-Mating Responses
3′ Untranslated Regions Mediate Transcriptional Interference between Convergent Genes Both Locally and Ectopically in
Single Nucleus Genome Sequencing Reveals High Similarity among Nuclei of an Endomycorrhizal Fungus
Metabolic QTL Analysis Links Chloroquine Resistance in to Impaired Hemoglobin Catabolism
Notch Controls Cell Adhesion in the Drosophila Eye
AL PHD-PRC1 Complexes Promote Seed Germination through H3K4me3-to-H3K27me3 Chromatin State Switch in Repression of Seed Developmental Genes
Genomes Reveal Evolution of Microalgal Oleaginous Traits
Large Inverted Duplications in the Human Genome Form via a Fold-Back Mechanism
Variation in Genome-Wide Levels of Meiotic Recombination Is Established at the Onset of Prophase in Mammalian Males
Age, Gender, and Cancer but Not Neurodegenerative and Cardiovascular Diseases Strongly Modulate Systemic Effect of the Apolipoprotein E4 Allele on Lifespan
Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response
Vestigialization of an Allosteric Switch: Genetic and Structural Mechanisms for the Evolution of Constitutive Activity in a Steroid Hormone Receptor
Functional Divergence and Evolutionary Turnover in Mammalian Phosphoproteomes
A 660-Kb Deletion with Antagonistic Effects on Fertility and Milk Production Segregates at High Frequency in Nordic Red Cattle: Additional Evidence for the Common Occurrence of Balancing Selection in Livestock
Comparative Evolutionary and Developmental Dynamics of the Cotton () Fiber Transcriptome
The Transcription Factor BcLTF1 Regulates Virulence and Light Responses in the Necrotrophic Plant Pathogen
Crossover Patterning by the Beam-Film Model: Analysis and Implications

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