Akutní farmakologická léčba psychotickédeprese

Acute Pharmacological Treatment of PsychoticDepression

In the submitted review the authors characterize the differences of psychotic and non-psychoticdepression. They give a brief account of the effectiveness of tricyclic antidepressants and classi-cal neuroleptics in the treatment of psychotic depression. The main part of the paper is devotedto a review on the use of amoxapine, selective inhibitors of the serotonin re-uptake and atypicalneuroleptics in acute treatment of depressive disorders with psychotic symptoms. Despite metho-dological limitations of the mentioned studies the authors conclude that these preparations aregaining their place in the treatment of psychotic depression.

Key words:
psychotic depression, classical neuroleptics, tricyclic antidepressants, SSRI, atypicalneuroleptics.