PLOS Pathogens - Číslo 7/2015

Research Matters

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Basic Prion Science “Spreads” Insight
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Research Driven by Curiosity: The Journey from Basic Molecular Biology and Virology to Studies of Human Pathogenic Coronaviruses

Opinion

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Mosquitoes Reset Malaria Parasites

Pearls

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Cross Kingdom Activators of Five Classes of Bacterial Effectors
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Deploying FLAREs to Visualize Functional Outcomes of Host—Pathogen Encounters
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The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease
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Extracellular Virions: The Advance Guard of Poxvirus Infections
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Risks of Antibiotic Exposures Early in Life on the Developing Microbiome
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RNA Virus Reassortment: An Evolutionary Mechanism for Host Jumps and Immune Evasion
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Exploiting Fungal Virulence-Regulating Transcription Factors As Novel Antifungal Drug Targets
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N-acetylglucosamine Regulates Virulence Properties in Microbial Pathogens
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Periodontal Diseases: Bug Induced, Host Promoted
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Mechanisms of Host Behavioral Change in Rodent Association
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The Emerging Role for RNA Polymerase II in Regulating Virulence Gene Expression in Malaria Parasites
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Turning Up the Heat: Inflammasome Activation by Fungal Pathogens
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On and Under the Skin: Emerging Basidiomycetous Yeast Infections Caused by Species

Review

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The DSF Family of Cell–Cell Signals: An Expanding Class of Bacterial Virulence Regulators

Research Article

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Vaccination Drives Changes in Metabolic and Virulence Profiles of
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Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein
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Analysis of the SUMO2 Proteome during HSV-1 Infection
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Capacity of Broadly Neutralizing Antibodies to Inhibit HIV-1 Cell-Cell Transmission Is Strain- and Epitope-Dependent
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A Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus Nucleoprotein
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The Endosymbiotic Bacterium Selectively Kills Male Hosts by Targeting the Masculinizing Gene
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HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days—Implications for HIV Remission
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Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of
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Transfer of Immunity from Mother to Offspring Is Mediated via Egg-Yolk Protein Vitellogenin
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Suppression of Long-Lived Humoral Immunity Following Infection
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The Role of VP1 Amino Acid Residue 145 of Enterovirus 71 in Viral Fitness and Pathogenesis in a Cynomolgus Monkey Model
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Utilizing Chemical Genomics to Identify Cytochrome as a Novel Drug Target for Chagas Disease
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EhVps32 Is a Vacuole-Associated Protein Involved in Pinocytosis and Phagocytosis of
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The Serine Protease EspC from Enteropathogenic Regulates Pore Formation and Cytotoxicity Mediated by the Type III Secretion System
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Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses
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Existing Infection Facilitates Establishment and Density of Malaria Parasites in Their Mosquito Vector
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Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice
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Neuronal Interferon Signaling Is Required for Protection against Herpes Simplex Virus Replication and Pathogenesis
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Epstein-Barr Virus Proteins EBNA3A and EBNA3C Together Induce Expression of the Oncogenic MicroRNA Cluster miR-221/miR-222 and Ablate Expression of Its Target p57
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Colonization of the Mouse Gastrointestinal Tract Is Modulated by Wall Teichoic Acid, Capsule, and Surface Proteins
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Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors
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Identification of Caspase Cleavage Sites in KSHV Latency-Associated Nuclear Antigen and Their Effects on Caspase-Related Host Defense Responses
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Calprotectin Increases the Activity of the SaeRS Two Component System and Murine Mortality during Infections
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Type VI Secretion System Transports Zn to Combat Multiple Stresses and Host Immunity
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Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIV/SIV/HIV-2 Lineage Prior to Integration
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Phenylbutyrate Is Bacteriostatic against and Regulates the Macrophage Response to Infection, Synergistically with 25-Hydroxy-Vitamin D₃
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A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence
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Vpu Exploits the Cross-Talk between BST2 and the ILT7 Receptor to Suppress Anti-HIV-1 Responses by Plasmacytoid Dendritic Cells
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Expression of the Blood-Group-Related Gene Alters Susceptibility to Infection
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Age-Dependent Cell Trafficking Defects in Draining Lymph Nodes Impair Adaptive Immunity and Control of West Nile Virus Infection
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Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS
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Latent KSHV Infected Endothelial Cells Are Glutamine Addicted and Require Glutaminolysis for Survival
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Intraperitoneal Infection of Wild-Type Mice with Synthetically Generated Mammalian Prion
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Vpr Promotes Macrophage-Dependent HIV-1 Infection of CD4 T Lymphocytes
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An In-Depth Comparison of Latency-Reversing Agent Combinations in Various and HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression
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α-Macroglobulin Can Crosslink Multiple Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes
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Should Symbionts Be Nice or Selfish? Antiviral Effects of Wolbachia Are Costly but Reproductive Parasitism Is Not
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A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface
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The Broad Neutralizing Antibody Responses after HIV-1 Superinfection Are Not Dominated by Antibodies Directed to Epitopes Common in Single Infection
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Rapidly Evolving Genes Are Key Players in Host Specialization and Virulence of the Fungal Wheat Pathogen ()
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MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease
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Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria
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Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation
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Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease
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Macrophages Subvert Adaptive Immunity to Urinary Tract Infection
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Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions
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Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection
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K-bZIP Mediated SUMO-2/3 Specific Modification on the KSHV Genome Negatively Regulates Lytic Gene Expression and Viral Reactivation
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Phosphoproteomic Analysis of KSHV-Infected Cells Reveals Roles of ORF45-Activated RSK during Lytic Replication
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CR3 and Dectin-1 Collaborate in Macrophage Cytokine Response through Association on Lipid Rafts and Activation of Syk-JNK-AP-1 Pathway
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IFNγ and IL-12 Restrict Th2 Responses during Helminth/ Co-Infection and Promote IFNγ from Th2 Cells
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THY-1 Cell Surface Antigen (CD90) Has an Important Role in the Initial Stage of Human Cytomegalovirus Infection
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Human Enterovirus Nonstructural Protein 2C Functions as Both an RNA Helicase and ATP-Independent RNA Chaperone
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IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4 T Cells and IFN-γ
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An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction

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