PLOS Genetics - Číslo 9/2010

Review

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Frail Hypotheses in Evolutionary Biology

Perspective

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Mutational Patterns Cannot Explain Genome Composition: Are There Any Neutral Sites in the Genomes of Bacteria?

Research Article

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Optimal Strategy for Competence Differentiation in Bacteria
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Differentiation of Zebrafish Melanophores Depends on Transcription Factors AP2 Alpha and AP2 Epsilon
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Effect of Correlated tRNA Abundances on Translation Errors and Evolution of Codon Usage Bias
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Evidence of Selection upon Genomic GC-Content in Bacteria
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Proteomic Changes Resulting from Gene Copy Number Variations in Cancer Cells
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Rice a Cinnamoyl-CoA Reductase-Like Gene Family Member, Is Required for NH1-Mediated Immunity to pv.
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Longitudinal Genome-Wide Association of Cardiovascular Disease Risk Factors in the Bogalusa Heart Study
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Response to Mechanical Stress Is Mediated by the TRPA Channel Painless in the Heart
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DNMT3L Modulates Significant and Distinct Flanking Sequence Preference for DNA Methylation by DNMT3A and DNMT3B
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Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data
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Incremental Genetic Perturbations to MCM2-7 Expression and Subcellular Distribution Reveal Exquisite Sensitivity of Mice to DNA Replication Stress
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Loss of Maternal ATRX Results in Centromere Instability and Aneuploidy in the Mammalian Oocyte and Pre-Implantation Embryo
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Comparative Genomic Hybridization (CGH) Reveals a Neo-X Chromosome and Biased Gene Movement in Stalk-Eyed Flies (Genus )
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Gene–Environment Interactions at Nucleotide Resolution
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A Single Element Maintains Repression of the Key Developmental Regulator
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Dementia Revealed: Novel Chromosome 6 Locus for Late-Onset Alzheimer Disease Provides Genetic Evidence for Folate-Pathway Abnormalities
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Critical Functions of Rpa3/Ssb3 in S-Phase DNA Damage Responses in Fission Yeast
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Preferential Re-Replication of Heterochromatin in the Absence of Geminin
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The Potential for Enhancing the Power of Genetic Association Studies in African Americans through the Reuse of Existing Genotype Data
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Evidence That Mutation Is Universally Biased towards AT in Bacteria
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Perturbation Analysis of Heterochromatin-Mediated Gene Silencing and Somatic Inheritance
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Diversity of Eukaryotic DNA Replication Origins Revealed by Genome-Wide Analysis of Chromatin Structure
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Genetic Deletion of the Desmosomal Component Promotes Tumor Microinvasion in a Mouse Model of Pancreatic Neuroendocrine Carcinogenesis
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The Metabolic Enzyme ManA Reveals a Link between Cell Wall Integrity and Chromosome Morphology
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SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer's Disease
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Synthesizing and Salvaging NAD: Lessons Learned from
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A Central Regulatory System Largely Controls Transcriptional Activation and Repression Responses to Phosphate Starvation in Arabidopsis
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Identification of New Genetic Risk Variants for Type 2 Diabetes
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The Genome of a Pathogenic : Cooptive Virulence Underpinned by Key Gene Acquisitions
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Genetic Architecture of Complex Traits and Accuracy of Genomic Prediction: Coat Colour, Milk-Fat Percentage, and Type in Holstein Cattle as Contrasting Model Traits
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Genetic Variants and Their Interactions in the Prediction of Increased Pre-Clinical Carotid Atherosclerosis: The Cardiovascular Risk in Young Finns Study
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Allelic Variation at the 8q23.3 Colorectal Cancer Risk Locus Functions as a Cis-Acting Regulator of
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Allelic Selection of Amplicons in Glioblastoma Revealed by Combining Somatic and Germline Analysis
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Germline Variation Controls the Architecture of Somatic Alterations in Tumors
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Mice Doubly-Deficient in Lysosomal Hexosaminidase A and Neuraminidase 4 Show Epileptic Crises and Rapid Neuronal Loss
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Analysis of Population Structure: A Unifying Framework and Novel Methods Based on Sparse Factor Analysis
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FliO Regulation of FliP in the Formation of the Flagellum
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Cdc20 Is Critical for Meiosis I and Fertility of Female Mice
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dMyc Functions Downstream of Yorkie to Promote the Supercompetitive Behavior of Hippo Pathway Mutant Cells
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DCAF26, an Adaptor Protein of Cul4-Based E3, Is Essential for DNA Methylation in
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Genome-Wide Double-Stranded RNA Sequencing Reveals the Functional Significance of Base-Paired RNAs in
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An Immune Response Network Associated with Blood Lipid Levels
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The Histone H3K36 Methyltransferase MES-4 Acts Epigenetically to Transmit the Memory of Germline Gene Expression to Progeny
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The Characterization of Twenty Sequenced Human Genomes
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Long- and Short-Term Selective Forces on Malaria Parasite Genomes
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Lactic Acidosis Triggers Starvation Response with Paradoxical Induction of TXNIP through MondoA
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Identification of Early Requirements for Preplacodal Ectoderm and Sensory Organ Development
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Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome
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Analysis of the Basidiomycete Reveals Conservation of the Core Meiotic Expression Program over Half a Billion Years of Evolution
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ETS-4 Is a Transcriptional Regulator of Life Span in
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The SR Protein B52/SRp55 Is Required for DNA Topoisomerase I Recruitment to Chromatin, mRNA Release and Transcription Shutdown
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The Baker's Yeast Diploid Genome Is Remarkably Stable in Vegetative Growth and Meiosis
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Chromatin Landscape Dictates HSF Binding to Target DNA Elements
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The APETALA-2-Like Transcription Factor OsAP2-39 Controls Key Interactions between Abscisic Acid and Gibberellin in Rice
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Accurately Assessing the Risk of Schizophrenia Conferred by Rare Copy-Number Variation Affecting Genes with Brain Function
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Widespread Over-Expression of the X Chromosome in Sterile F Hybrid Mice
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An Insect Herbivore Microbiome with High Plant Biomass-Degrading Capacity

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