PLOS Genetics - Číslo 9/2010


Mutational Patterns Cannot Explain Genome Composition: Are There Any Neutral Sites in the Genomes of Bacteria?


Frail Hypotheses in Evolutionary Biology

Research Article

Optimal Strategy for Competence Differentiation in Bacteria
Genetic Architecture of Complex Traits and Accuracy of Genomic Prediction: Coat Colour, Milk-Fat Percentage, and Type in Holstein Cattle as Contrasting Model Traits
Allelic Variation at the 8q23.3 Colorectal Cancer Risk Locus Functions as a Cis-Acting Regulator of
Allelic Selection of Amplicons in Glioblastoma Revealed by Combining Somatic and Germline Analysis
Germline Variation Controls the Architecture of Somatic Alterations in Tumors
Mice Doubly-Deficient in Lysosomal Hexosaminidase A and Neuraminidase 4 Show Epileptic Crises and Rapid Neuronal Loss
Analysis of Population Structure: A Unifying Framework and Novel Methods Based on Sparse Factor Analysis
FliO Regulation of FliP in the Formation of the Flagellum
Cdc20 Is Critical for Meiosis I and Fertility of Female Mice
dMyc Functions Downstream of Yorkie to Promote the Supercompetitive Behavior of Hippo Pathway Mutant Cells
DCAF26, an Adaptor Protein of Cul4-Based E3, Is Essential for DNA Methylation in
Genome-Wide Double-Stranded RNA Sequencing Reveals the Functional Significance of Base-Paired RNAs in
An Immune Response Network Associated with Blood Lipid Levels
Genetic Variants and Their Interactions in the Prediction of Increased Pre-Clinical Carotid Atherosclerosis: The Cardiovascular Risk in Young Finns Study
The Histone H3K36 Methyltransferase MES-4 Acts Epigenetically to Transmit the Memory of Germline Gene Expression to Progeny
Long- and Short-Term Selective Forces on Malaria Parasite Genomes
Lactic Acidosis Triggers Starvation Response with Paradoxical Induction of TXNIP through MondoA
Identification of Early Requirements for Preplacodal Ectoderm and Sensory Organ Development
Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome
Analysis of the Basidiomycete Reveals Conservation of the Core Meiotic Expression Program over Half a Billion Years of Evolution
ETS-4 Is a Transcriptional Regulator of Life Span in
The SR Protein B52/SRp55 Is Required for DNA Topoisomerase I Recruitment to Chromatin, mRNA Release and Transcription Shutdown
The Baker's Yeast Diploid Genome Is Remarkably Stable in Vegetative Growth and Meiosis
Chromatin Landscape Dictates HSF Binding to Target DNA Elements
The APETALA-2-Like Transcription Factor OsAP2-39 Controls Key Interactions between Abscisic Acid and Gibberellin in Rice
Accurately Assessing the Risk of Schizophrenia Conferred by Rare Copy-Number Variation Affecting Genes with Brain Function
Widespread Over-Expression of the X Chromosome in Sterile F Hybrid Mice
The Characterization of Twenty Sequenced Human Genomes
The Genome of a Pathogenic : Cooptive Virulence Underpinned by Key Gene Acquisitions
A Single Element Maintains Repression of the Key Developmental Regulator
Identification of New Genetic Risk Variants for Type 2 Diabetes
Effect of Correlated tRNA Abundances on Translation Errors and Evolution of Codon Usage Bias
Evidence of Selection upon Genomic GC-Content in Bacteria
Proteomic Changes Resulting from Gene Copy Number Variations in Cancer Cells
Rice a Cinnamoyl-CoA Reductase-Like Gene Family Member, Is Required for NH1-Mediated Immunity to pv.
Longitudinal Genome-Wide Association of Cardiovascular Disease Risk Factors in the Bogalusa Heart Study
Response to Mechanical Stress Is Mediated by the TRPA Channel Painless in the Heart
DNMT3L Modulates Significant and Distinct Flanking Sequence Preference for DNA Methylation by DNMT3A and DNMT3B
Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data
Incremental Genetic Perturbations to MCM2-7 Expression and Subcellular Distribution Reveal Exquisite Sensitivity of Mice to DNA Replication Stress
Loss of Maternal ATRX Results in Centromere Instability and Aneuploidy in the Mammalian Oocyte and Pre-Implantation Embryo
Comparative Genomic Hybridization (CGH) Reveals a Neo-X Chromosome and Biased Gene Movement in Stalk-Eyed Flies (Genus )
Differentiation of Zebrafish Melanophores Depends on Transcription Factors AP2 Alpha and AP2 Epsilon
Gene–Environment Interactions at Nucleotide Resolution
Dementia Revealed: Novel Chromosome 6 Locus for Late-Onset Alzheimer Disease Provides Genetic Evidence for Folate-Pathway Abnormalities
Critical Functions of Rpa3/Ssb3 in S-Phase DNA Damage Responses in Fission Yeast
Preferential Re-Replication of Heterochromatin in the Absence of Geminin
The Potential for Enhancing the Power of Genetic Association Studies in African Americans through the Reuse of Existing Genotype Data
Evidence That Mutation Is Universally Biased towards AT in Bacteria
Perturbation Analysis of Heterochromatin-Mediated Gene Silencing and Somatic Inheritance
Diversity of Eukaryotic DNA Replication Origins Revealed by Genome-Wide Analysis of Chromatin Structure
Genetic Deletion of the Desmosomal Component Promotes Tumor Microinvasion in a Mouse Model of Pancreatic Neuroendocrine Carcinogenesis
The Metabolic Enzyme ManA Reveals a Link between Cell Wall Integrity and Chromosome Morphology
SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer's Disease
Synthesizing and Salvaging NAD: Lessons Learned from
A Central Regulatory System Largely Controls Transcriptional Activation and Repression Responses to Phosphate Starvation in Arabidopsis
An Insect Herbivore Microbiome with High Plant Biomass-Degrading Capacity

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