PLOS Genetics - Číslo 12/2010


Cancer and Neurodegeneration: Between the Devil and the Deep Blue Sea


Linking Crohn's Disease and Ankylosing Spondylitis: It's All about Genes!

Research Article

Genome-Wide Interrogation of Mammalian Stem Cell Fate Determinants by Nested Chromosome Deletions
Whole-Genome and Chromosome Evolution Associated with Host Adaptation and Speciation of the Wheat Pathogen
Association of Variants at 1q32 and with Ankylosing Spondylitis Suggests Genetic Overlap with Crohn's Disease
Initiator Elements Function to Determine the Activity State of BX-C Enhancers
Identification of Genes Required for Neural-Specific Glycosylation Using Functional Genomics
A Young Duplicate Gene Plays Essential Roles in Spermatogenesis by Regulating Several Y-Linked Male Fertility Genes
The EpsE Flagellar Clutch Is Bifunctional and Synergizes with EPS Biosynthesis to Promote Biofilm Formation
Histone H2A C-Terminus Regulates Chromatin Dynamics, Remodeling, and Histone H1 Binding
Season of Conception in Rural Gambia Affects DNA Methylation at Putative Human Metastable Epialleles
A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells
A Single Enhancer Regulating the Differential Expression of Duplicated Red-Sensitive Opsin Genes in Zebrafish
Investigation and Functional Characterization of Rare Genetic Variants in the Adipose Triglyceride Lipase in a Large Healthy Working Population
Reduction of Protein Translation and Activation of Autophagy Protect against PINK1 Pathogenesis in
Noisy Splicing Drives mRNA Isoform Diversity in Human Cells
The Loss of PGAM5 Suppresses the Mitochondrial Degeneration Caused by Inactivation of PINK1 in
Thymus-Associated Parathyroid Hormone Has Two Cellular Origins with Distinct Endocrine and Immunological Functions
An ABC Transporter Mutation Is Correlated with Insect Resistance to Cry1Ac Toxin
Role of Individual Subunits of the CSN Complex in Regulation of Deneddylation and Stability of Cullin Proteins
The C-Terminal Domain of the Bacterial SSB Protein Acts as a DNA Maintenance Hub at Active Chromosome Replication Forks
The DNA Damage Response Pathway Contributes to the Stability of Chromosome III Derivatives Lacking Efficient Replicators
Cleavage of Phosphorothioated DNA and Methylated DNA by the Type IV Restriction Endonuclease ScoMcrA
LaeA Control of Velvet Family Regulatory Proteins for Light-Dependent Development and Fungal Cell-Type Specificity
Competitive Repair by Naturally Dispersed Repetitive DNA during Non-Allelic Homologous Recombination
Distinct Functions for the piRNA Pathway in Genome Maintenance and Telomere Protection
MOS11: A New Component in the mRNA Export Pathway
Self-Mating in the Definitive Host Potentiates Clonal Outbreaks of the Apicomplexan Parasites and
A Role for ATF2 in Regulating MITF and Melanoma Development
Ancestral Regulatory Circuits Governing Ectoderm Patterning Downstream of Nodal and BMP2/4 Revealed by Gene Regulatory Network Analysis in an Echinoderm
Functional Comparison of Innate Immune Signaling Pathways in Primates
Genomics Meets Glycomics—The First GWAS Study of Human N-Glycome Identifies HNF1α as a Master Regulator of Plasma Protein Fucosylation
Continuous and Periodic Expansion of CAG Repeats in Huntington's Disease R6/1 Mice
Expression of Linear and Novel Circular Forms of an -Associated Non-Coding RNA Correlates with Atherosclerosis Risk
Endocytic Sorting and Recycling Require Membrane Phosphatidylserine Asymmetry Maintained by TAT-1/CHAT-1
Histone Deacetylases Suppress CGG Repeat–Induced Neurodegeneration Via Transcriptional Silencing in Models of Fragile X Tremor Ataxia Syndrome

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