PLOS Genetics - Číslo 10/2010

Perspective

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FSHD: A Repeat Contraction Disease Finally Ready to Expand (Our Understanding of Its Pathogenesis)

Research Article

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Common Genetic Variants and Modification of Penetrance of -Associated Breast Cancer
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Characterization of LINE-1 Ribonucleoprotein Particles
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Regulates Tissue-Specific Mitochondrial DNA Segregation
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Comprehensive Analysis Reveals Dynamic and Evolutionary Plasticity of Rab GTPases and Membrane Traffic in
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Transition from Positive to Neutral in Mutation Fixation along with Continuing Rising Fitness in Thermal Adaptive Evolution
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Pervasive Cryptic Epistasis in Molecular Evolution
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Dual Functions of ASCIZ in the DNA Base Damage Response and Pulmonary Organogenesis
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Characterising and Predicting Haploinsufficiency in the Human Genome
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Simultaneous Disruption of Two DNA Polymerases, Polη and Polζ, in Avian DT40 Cells Unmasks the Role of Polη in Cellular Response to Various DNA Lesions
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H3K27me3 Profiling of the Endosperm Implies Exclusion of Polycomb Group Protein Targeting by DNA Methylation
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Stress-Induced Activation of Heterochromatic Transcription
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Nasty Viruses, Costly Plasmids, Population Dynamics, and the Conditions for Establishing and Maintaining CRISPR-Mediated Adaptive Immunity in Bacteria
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Conjugative DNA Transfer Induces the Bacterial SOS Response and Promotes Antibiotic Resistance Development through Integron Activation
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Tight Regulation of the Gene of the KplE1 Prophage: A New Paradigm for Integrase Gene Regulation
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Alternative Splicing at a NAGNAG Acceptor Site as a Novel Phenotype Modifier
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Conserved Genes Act as Modifiers of Invertebrate SMN Loss of Function Defects
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Altering a Histone H3K4 Methylation Pathway in Glomerular Podocytes Promotes a Chronic Disease Phenotype
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Genome-Wide Identification of Targets and Function of Individual MicroRNAs in Mouse Embryonic Stem Cells
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Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis
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Ancient and Recent Adaptive Evolution of Primate Non-Homologous End Joining Genes
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Lifespan Extension by Preserving Proliferative Homeostasis in
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Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation
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Evidence for a Xer/ System for Chromosome Resolution in Archaea
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Genetic Association Study Identifies as a Risk Gene for Idiopathic Dilated Cardiomyopathy
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β-Actin and γ-Actin Are Each Dispensable for Auditory Hair Cell Development But Required for Stereocilia Maintenance
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The Cytosine Methyltransferase DRM2 Requires Intact UBA Domains and a Catalytically Mutated Paralog DRM3 during RNA–Directed DNA Methylation in
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Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near Associated with Hypertension
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Continuous Requirement for the Clr4 Complex But Not RNAi for Centromeric Heterochromatin Assembly in Fission Yeast Harboring a Disrupted RITS Complex
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DSIF and RNA Polymerase II CTD Phosphorylation Coordinate the Recruitment of Rpd3S to Actively Transcribed Genes
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Actin Depolymerizing Factors Cofilin1 and Destrin Are Required for Ureteric Bud Branching Morphogenesis
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The Meiotic Recombination Checkpoint Suppresses NHK-1 Kinase to Prevent Reorganisation of the Oocyte Nucleus in
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Allele-Specific Down-Regulation of Expression Induced by Retinoids Contributes to Climate Adaptations
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Role for the Mammalian Swi5-Sfr1 Complex in DNA Strand Break Repair through Homologous Recombination

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