PLOS Pathogens - Číslo 6/2015

Research Matters

32767
The Curious Road from Basic Pathogen Research to Clinical Translation
From Cell and Organismal Biology to Drugs

Editorial

32767
Introducing “Research Matters”

Pearls

32767
Exploring Host–Pathogen Interactions through Biological Control
Analysis of Bottlenecks in Experimental Models of Infection
Expected and Unexpected Features of the Newly Discovered Bat Influenza A-like Viruses
Host Delivery of Favorite Meals for Intracellular Pathogens
Adenovirus Tales: From the Cell Surface to the Nuclear Pore Complex
A 21st Century Perspective of Poliovirus Replication
Is Development of a Vaccine against Feasible?
Waterborne Viruses: A Barrier to Safe Drinking Water
Battling Phages: How Bacteria Defend against Viral Attack
Archaea in and on the Human Body: Health Implications and Future Directions
Successes and Challenges on the Road to Cure Hepatitis C

Review

32767
Targeting Human Transmission Biology for Malaria Elimination

Research Article

32767
Clearance of Pneumococcal Colonization in Infants Is Delayed through Altered Macrophage Trafficking
Recombinant Murine Gamma Herpesvirus 68 Carrying KSHV G Protein-Coupled Receptor Induces Angiogenic Lesions in Mice
TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING
Two Cdc2 Kinase Genes with Distinct Functions in Vegetative and Infectious Hyphae in
An Model of Latency and Reactivation of Varicella Zoster Virus in Human Stem Cell-Derived Neurons
Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs
Virulence Factors of Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells
Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation
Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis
An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation
The Role of Human Transportation Networks in Mediating the Genetic Structure of Seasonal Influenza in the United States
Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells
Inter-Seasonal Influenza is Characterized by Extended Virus Transmission and Persistence
A Critical Role for CLSP2 in the Modulation of Antifungal Immune Response in Mosquitoes
Twilight, a Novel Circadian-Regulated Gene, Integrates Phototropism with Nutrient and Redox Homeostasis during Fungal Development
Surface-Associated Lipoproteins Link Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels
Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells
Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains
Neuronal Subtype and Satellite Cell Tropism Are Determinants of Varicella-Zoster Virus Virulence in Human Dorsal Root Ganglia Xenografts
Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate
Structure of the Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome
Activated Brain Endothelial Cells Cross-Present Malaria Antigen
Fungal Morphology, Iron Homeostasis, and Lipid Metabolism Regulated by a GATA Transcription Factor in
Peptidoglycan Branched Stem Peptides Contribute to Virulence by Inhibiting Pneumolysin Release
A Macrophage Subversion Factor Is Shared by Intracellular and Extracellular Pathogens
A Novel AT-Rich DNA Recognition Mechanism for Bacterial Xenogeneic Silencer MvaT
Reovirus FAST Proteins Drive Pore Formation and Syncytiogenesis Using a Novel Helix-Loop-Helix Fusion-Inducing Lipid Packing Sensor
The Role of ExoS in Dissemination of during Pneumonia
IRF-5-Mediated Inflammation Limits CD8 T Cell Expansion by Inducing HIF-1α and Impairing Dendritic Cell Functions during Infection
Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection
Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7
HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells
HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures
The νSaα Specific Lipoprotein Like Cluster () of . USA300 Contributes to Immune Stimulation and Invasion in Human Cells
RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis
Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular
Border Patrol Gone Awry: Lung NKT Cell Activation by Exacerbates Tularemia-Like Disease
Degradation of Human PDZ-Proteins by Human Alphapapillomaviruses Represents an Evolutionary Adaptation to a Novel Cellular Niche
Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability
Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers
The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly
Host Reticulocytes Provide Metabolic Reservoirs That Can Be Exploited by Malaria Parasites
The Proteome of the Isolated Containing Vacuole Reveals a Complex Trafficking Platform Enriched for Retromer Components
NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia
BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses
A Structural and Functional Comparison Between Infectious and Non-Infectious Autocatalytic Recombinant PrP Conformers
Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria
Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration
Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes
EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival
Single-Cell and Single-Cycle Analysis of HIV-1 Replication
TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase
The Herpes Simplex Virus Protein pUL31 Escorts Nucleocapsids to Sites of Nuclear Egress, a Process Coordinated by Its N-Terminal Domain
Host Transcriptional Response to Influenza and Other Acute Respiratory Viral Infections – A Prospective Cohort Study

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