PLOS Genetics - Číslo 2/2015


2014 Reviewer Thank You


Closing the Gap between Knowledge and Clinical Application: Challenges for Genomic Translation


and Hyperdrive Mechanisms (in Mouse Meiosis)

Research Article

Systematic Cell-Based Phenotyping of Missense Alleles Empowers Rare Variant Association Studies: A Case for and Myocardial Infarction
African Glucose-6-Phosphate Dehydrogenase Alleles Associated with Protection from Severe Malaria in Heterozygous Females in Tanzania
Genomics of Divergence along a Continuum of Parapatric Population Differentiation
microRNAs Regulate Cell-to-Cell Variability of Endogenous Target Gene Expression in Developing Mouse Thymocytes
A Rolling Circle Replication Mechanism Produces Multimeric Lariats of Mitochondrial DNA in
Partially Redundant Enhancers Cooperatively Maintain Mammalian Expression Above a Critical Functional Threshold
Discovery of Transcription Factors and Regulatory Regions Driving Tumor Development by ATAC-seq and FAIRE-seq Open Chromatin Profiling
Mutations in Result in Ocular Coloboma, Microcornea and Cataracts
A Genome-Wide Hybrid Incompatibility Landscape between and
Recurrent Evolution of Melanism in South American Felids
Discovery of CTCF-Sensitive Cis-Spliced Fusion RNAs between Adjacent Genes in Human Prostate Cells
Tissue Expression Pattern of PMK-2 p38 MAPK Is Established by the miR-58 Family in
Essential Role for Endogenous siRNAs during Meiosis in Mouse Oocytes
Matrix Metalloproteinase 2 Is Required for Ovulation and Corpus Luteum Formation in
Evolutionary Signatures amongst Disease Genes Permit Novel Methods for Gene Prioritization and Construction of Informative Gene-Based Networks
RR-1 Cuticular Protein TcCPR4 Is Required for Formation of Pore Canals in Rigid Cuticle
GC-Content Evolution in Bacterial Genomes: The Biased Gene Conversion Hypothesis Expands
Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates
K-homology Nuclear Ribonucleoproteins Regulate Floral Organ Identity and Determinacy in Arabidopsis
A Nitric Oxide Regulated Small RNA Controls Expression of Genes Involved in Redox Homeostasis in
HYPER RECOMBINATION1 of the THO/TREX Complex Plays a Role in Controlling Transcription of the Gene in Arabidopsis
Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan
Structured Observations Reveal Slow HIV-1 CTL Escape
An Integrative Multi-scale Analysis of the Dynamic DNA Methylation Landscape in Aging
Combining Natural Sequence Variation with High Throughput Mutational Data to Reveal Protein Interaction Sites
Transhydrogenase Promotes the Robustness and Evolvability of Deficient in NADPH Production
Regulators of Autophagosome Formation in Muscles
Genomic Selection and Association Mapping in Rice (): Effect of Trait Genetic Architecture, Training Population Composition, Marker Number and Statistical Model on Accuracy of Rice Genomic Selection in Elite, Tropical Rice Breeding Lines
Eye Selector Logic for a Coordinated Cell Cycle Exit
Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations
The DNA Polymerase δ Has a Role in the Deposition of Transcriptionally Active Epigenetic Marks, Development and Flowering
Contribution of the Two Genes Encoding Histone Variant H3.3 to Viability and Fertility in Mice
Membrane Recognition and Dynamics of the RNA Degradosome
P-TEFb, the Super Elongation Complex and Mediator Regulate a Subset of Non-paused Genes during Early Embryo Development
is a Long Non-coding RNA in JNK Signaling in Epithelial Shape Changes during Drosophila Dorsal Closure
A Pleiotropy-Informed Bayesian False Discovery Rate Adapted to a Shared Control Design Finds New Disease Associations From GWAS Summary Statistics
Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers
Elevated In Vivo Levels of a Single Transcription Factor Directly Convert Satellite Glia into Oligodendrocyte-like Cells
Systemic Delivery of MicroRNA-101 Potently Inhibits Hepatocellular Carcinoma by Repressing Multiple Targets
Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in and Implicates Other Immune Related Genes
Abscission Is Regulated by the ESCRT-III Protein Shrub in Germline Stem Cells
Temperature Stress Mediates Decanalization and Dominance of Gene Expression in
Transcriptome Wide Annotation of Eukaryotic RNase III Reactivity and Degradation Signals
The Exosome Component Rrp6 Is Required for RNA Polymerase II Termination at Specific Targets of the Nrd1-Nab3 Pathway
Sex-specific -regulatory Variation on the X Chromosome
Regulation of Toll-like Receptor Signaling by the SF3a mRNA Splicing Complex
Modeling of the Human Alveolar Rhabdomyosarcoma Chromosome Translocation in Mouse Myoblasts Using CRISPR-Cas9 Nuclease
Asymmetry of the Budding Yeast Tem1 GTPase at Spindle Poles Is Required for Spindle Positioning But Not for Mitotic Exit
TIM Binds Importin α1, and Acts as an Adapter to Transport PER to the Nucleus
Antagonistic Roles for KNOX1 and KNOX2 Genes in Patterning the Land Plant Body Plan Following an Ancient Gene Duplication
The Genetic Architecture of the Genome-Wide Transcriptional Response to ER Stress in the Mouse
Fatty Acid Synthase Cooperates with Glyoxalase 1 to Protect against Sugar Toxicity
Region-Specific Activation of mRNA Translation by Inhibition of Bruno-Mediated Repression
An Essential Role of the Arginine Vasotocin System in Mate-Guarding Behaviors in Triadic Relationships of Medaka Fish ()
Interaction between the tRNA-Binding and C-Terminal Domains of Yeast Gcn2 Regulates Kinase Activity In Vivo
Hyper-Acetylation of Histone H3K56 Limits Break-Induced Replication by Inhibiting Extensive Repair Synthesis
Prodomain Removal Enables Neto to Stabilize Glutamate Receptors at the Neuromuscular Junction
Recent Selective Sweeps in North American Show Signatures of Soft Sweeps
Identification and Functional Analysis of Healing Regulators in
A Multi-Megabase Copy Number Gain Causes Maternal Transmission Ratio Distortion on Mouse Chromosome 2
Drosophila Casein Kinase I Alpha Regulates Homolog Pairing and Genome Organization by Modulating Condensin II Subunit Cap-H2 Levels
The Hippo Pathway Regulates Homeostatic Growth of Stem Cell Niche Precursors in the Ovary

Kurzy Doporučená témata Časopisy
Zapomenuté heslo

Nemáte účet?  Registrujte se

Zapomenuté heslo

Zadejte e-mailovou adresu se kterou jste vytvářel(a) účet, budou Vám na ni zaslány informace k nastavení nového hesla.


Nemáte účet?  Registrujte se

VIRTUÁLNÍ ČEKÁRNA ČR Jste praktický lékař nebo pediatr? Zapojte se! Jste praktik nebo pediatr? Zapojte se!