PLOS Genetics - Číslo 2/2015

Editorial

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2014 Reviewer Thank You

Review

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Closing the Gap between Knowledge and Clinical Application: Challenges for Genomic Translation

Perspective

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and Hyperdrive Mechanisms (in Mouse Meiosis)

Research Article

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Systematic Cell-Based Phenotyping of Missense Alleles Empowers Rare Variant Association Studies: A Case for and Myocardial Infarction
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Modeling of the Human Alveolar Rhabdomyosarcoma Chromosome Translocation in Mouse Myoblasts Using CRISPR-Cas9 Nuclease
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is a Long Non-coding RNA in JNK Signaling in Epithelial Shape Changes during Drosophila Dorsal Closure
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A Pleiotropy-Informed Bayesian False Discovery Rate Adapted to a Shared Control Design Finds New Disease Associations From GWAS Summary Statistics
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Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers
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Elevated In Vivo Levels of a Single Transcription Factor Directly Convert Satellite Glia into Oligodendrocyte-like Cells
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Systemic Delivery of MicroRNA-101 Potently Inhibits Hepatocellular Carcinoma by Repressing Multiple Targets
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Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in and Implicates Other Immune Related Genes
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Abscission Is Regulated by the ESCRT-III Protein Shrub in Germline Stem Cells
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Temperature Stress Mediates Decanalization and Dominance of Gene Expression in
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Transcriptome Wide Annotation of Eukaryotic RNase III Reactivity and Degradation Signals
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The Exosome Component Rrp6 Is Required for RNA Polymerase II Termination at Specific Targets of the Nrd1-Nab3 Pathway
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Sex-specific -regulatory Variation on the X Chromosome
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Regulation of Toll-like Receptor Signaling by the SF3a mRNA Splicing Complex
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Asymmetry of the Budding Yeast Tem1 GTPase at Spindle Poles Is Required for Spindle Positioning But Not for Mitotic Exit
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Membrane Recognition and Dynamics of the RNA Degradosome
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TIM Binds Importin α1, and Acts as an Adapter to Transport PER to the Nucleus
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Antagonistic Roles for KNOX1 and KNOX2 Genes in Patterning the Land Plant Body Plan Following an Ancient Gene Duplication
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The Genetic Architecture of the Genome-Wide Transcriptional Response to ER Stress in the Mouse
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Fatty Acid Synthase Cooperates with Glyoxalase 1 to Protect against Sugar Toxicity
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Region-Specific Activation of mRNA Translation by Inhibition of Bruno-Mediated Repression
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An Essential Role of the Arginine Vasotocin System in Mate-Guarding Behaviors in Triadic Relationships of Medaka Fish ()
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Interaction between the tRNA-Binding and C-Terminal Domains of Yeast Gcn2 Regulates Kinase Activity In Vivo
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Hyper-Acetylation of Histone H3K56 Limits Break-Induced Replication by Inhibiting Extensive Repair Synthesis
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Prodomain Removal Enables Neto to Stabilize Glutamate Receptors at the Neuromuscular Junction
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Recent Selective Sweeps in North American Show Signatures of Soft Sweeps
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Identification and Functional Analysis of Healing Regulators in
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A Multi-Megabase Copy Number Gain Causes Maternal Transmission Ratio Distortion on Mouse Chromosome 2
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Drosophila Casein Kinase I Alpha Regulates Homolog Pairing and Genome Organization by Modulating Condensin II Subunit Cap-H2 Levels
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P-TEFb, the Super Elongation Complex and Mediator Regulate a Subset of Non-paused Genes during Early Embryo Development
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Contribution of the Two Genes Encoding Histone Variant H3.3 to Viability and Fertility in Mice
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African Glucose-6-Phosphate Dehydrogenase Alleles Associated with Protection from Severe Malaria in Heterozygous Females in Tanzania
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RR-1 Cuticular Protein TcCPR4 Is Required for Formation of Pore Canals in Rigid Cuticle
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Genomics of Divergence along a Continuum of Parapatric Population Differentiation
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microRNAs Regulate Cell-to-Cell Variability of Endogenous Target Gene Expression in Developing Mouse Thymocytes
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A Rolling Circle Replication Mechanism Produces Multimeric Lariats of Mitochondrial DNA in
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Partially Redundant Enhancers Cooperatively Maintain Mammalian Expression Above a Critical Functional Threshold
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Discovery of Transcription Factors and Regulatory Regions Driving Tumor Development by ATAC-seq and FAIRE-seq Open Chromatin Profiling
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Mutations in Result in Ocular Coloboma, Microcornea and Cataracts
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A Genome-Wide Hybrid Incompatibility Landscape between and
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Recurrent Evolution of Melanism in South American Felids
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Discovery of CTCF-Sensitive Cis-Spliced Fusion RNAs between Adjacent Genes in Human Prostate Cells
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Tissue Expression Pattern of PMK-2 p38 MAPK Is Established by the miR-58 Family in
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Essential Role for Endogenous siRNAs during Meiosis in Mouse Oocytes
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Matrix Metalloproteinase 2 Is Required for Ovulation and Corpus Luteum Formation in
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Evolutionary Signatures amongst Disease Genes Permit Novel Methods for Gene Prioritization and Construction of Informative Gene-Based Networks
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GC-Content Evolution in Bacterial Genomes: The Biased Gene Conversion Hypothesis Expands
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The DNA Polymerase δ Has a Role in the Deposition of Transcriptionally Active Epigenetic Marks, Development and Flowering
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Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates
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K-homology Nuclear Ribonucleoproteins Regulate Floral Organ Identity and Determinacy in Arabidopsis
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A Nitric Oxide Regulated Small RNA Controls Expression of Genes Involved in Redox Homeostasis in
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HYPER RECOMBINATION1 of the THO/TREX Complex Plays a Role in Controlling Transcription of the Gene in Arabidopsis
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Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan
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Structured Observations Reveal Slow HIV-1 CTL Escape
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An Integrative Multi-scale Analysis of the Dynamic DNA Methylation Landscape in Aging
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Combining Natural Sequence Variation with High Throughput Mutational Data to Reveal Protein Interaction Sites
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Transhydrogenase Promotes the Robustness and Evolvability of Deficient in NADPH Production
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Regulators of Autophagosome Formation in Muscles
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Genomic Selection and Association Mapping in Rice (): Effect of Trait Genetic Architecture, Training Population Composition, Marker Number and Statistical Model on Accuracy of Rice Genomic Selection in Elite, Tropical Rice Breeding Lines
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Eye Selector Logic for a Coordinated Cell Cycle Exit
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Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations
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The Hippo Pathway Regulates Homeostatic Growth of Stem Cell Niche Precursors in the Ovary

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