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PLOS Genetics - Číslo 2/2015

Research Article

32767

Systematic Cell-Based Phenotyping of Missense Alleles Empowers Rare Variant Association Studies: A Case for and Myocardial Infarction

African Glucose-6-Phosphate Dehydrogenase Alleles Associated with Protection from Severe Malaria in Heterozygous Females in Tanzania

Genomics of Divergence along a Continuum of Parapatric Population Differentiation

microRNAs Regulate Cell-to-Cell Variability of Endogenous Target Gene Expression in Developing Mouse Thymocytes

A Rolling Circle Replication Mechanism Produces Multimeric Lariats of Mitochondrial DNA in

Partially Redundant Enhancers Cooperatively Maintain Mammalian Expression Above a Critical Functional Threshold

Discovery of Transcription Factors and Regulatory Regions Driving Tumor Development by ATAC-seq and FAIRE-seq Open Chromatin Profiling

Mutations in Result in Ocular Coloboma, Microcornea and Cataracts

A Genome-Wide Hybrid Incompatibility Landscape between and

Recurrent Evolution of Melanism in South American Felids

Discovery of CTCF-Sensitive Cis-Spliced Fusion RNAs between Adjacent Genes in Human Prostate Cells

Tissue Expression Pattern of PMK-2 p38 MAPK Is Established by the miR-58 Family in

Essential Role for Endogenous siRNAs during Meiosis in Mouse Oocytes

Matrix Metalloproteinase 2 Is Required for Ovulation and Corpus Luteum Formation in

Evolutionary Signatures amongst Disease Genes Permit Novel Methods for Gene Prioritization and Construction of Informative Gene-Based Networks

RR-1 Cuticular Protein TcCPR4 Is Required for Formation of Pore Canals in Rigid Cuticle

GC-Content Evolution in Bacterial Genomes: The Biased Gene Conversion Hypothesis Expands

Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates

K-homology Nuclear Ribonucleoproteins Regulate Floral Organ Identity and Determinacy in Arabidopsis

A Nitric Oxide Regulated Small RNA Controls Expression of Genes Involved in Redox Homeostasis in

HYPER RECOMBINATION1 of the THO/TREX Complex Plays a Role in Controlling Transcription of the Gene in Arabidopsis

Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan

Structured Observations Reveal Slow HIV-1 CTL Escape

An Integrative Multi-scale Analysis of the Dynamic DNA Methylation Landscape in Aging

Combining Natural Sequence Variation with High Throughput Mutational Data to Reveal Protein Interaction Sites

Transhydrogenase Promotes the Robustness and Evolvability of Deficient in NADPH Production

Regulators of Autophagosome Formation in Muscles

Genomic Selection and Association Mapping in Rice (): Effect of Trait Genetic Architecture, Training Population Composition, Marker Number and Statistical Model on Accuracy of Rice Genomic Selection in Elite, Tropical Rice Breeding Lines

Eye Selector Logic for a Coordinated Cell Cycle Exit

Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations

The DNA Polymerase δ Has a Role in the Deposition of Transcriptionally Active Epigenetic Marks, Development and Flowering

Contribution of the Two Genes Encoding Histone Variant H3.3 to Viability and Fertility in Mice

Membrane Recognition and Dynamics of the RNA Degradosome

P-TEFb, the Super Elongation Complex and Mediator Regulate a Subset of Non-paused Genes during Early Embryo Development

is a Long Non-coding RNA in JNK Signaling in Epithelial Shape Changes during Drosophila Dorsal Closure

A Pleiotropy-Informed Bayesian False Discovery Rate Adapted to a Shared Control Design Finds New Disease Associations From GWAS Summary Statistics

Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers

Elevated In Vivo Levels of a Single Transcription Factor Directly Convert Satellite Glia into Oligodendrocyte-like Cells

Systemic Delivery of MicroRNA-101 Potently Inhibits Hepatocellular Carcinoma by Repressing Multiple Targets

Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in and Implicates Other Immune Related Genes

Abscission Is Regulated by the ESCRT-III Protein Shrub in Germline Stem Cells

Temperature Stress Mediates Decanalization and Dominance of Gene Expression in

Transcriptome Wide Annotation of Eukaryotic RNase III Reactivity and Degradation Signals

The Exosome Component Rrp6 Is Required for RNA Polymerase II Termination at Specific Targets of the Nrd1-Nab3 Pathway

Sex-specific -regulatory Variation on the X Chromosome

Regulation of Toll-like Receptor Signaling by the SF3a mRNA Splicing Complex

Modeling of the Human Alveolar Rhabdomyosarcoma Chromosome Translocation in Mouse Myoblasts Using CRISPR-Cas9 Nuclease

Asymmetry of the Budding Yeast Tem1 GTPase at Spindle Poles Is Required for Spindle Positioning But Not for Mitotic Exit

TIM Binds Importin α1, and Acts as an Adapter to Transport PER to the Nucleus

Antagonistic Roles for KNOX1 and KNOX2 Genes in Patterning the Land Plant Body Plan Following an Ancient Gene Duplication

The Genetic Architecture of the Genome-Wide Transcriptional Response to ER Stress in the Mouse

Fatty Acid Synthase Cooperates with Glyoxalase 1 to Protect against Sugar Toxicity

Region-Specific Activation of mRNA Translation by Inhibition of Bruno-Mediated Repression

An Essential Role of the Arginine Vasotocin System in Mate-Guarding Behaviors in Triadic Relationships of Medaka Fish ()

Interaction between the tRNA-Binding and C-Terminal Domains of Yeast Gcn2 Regulates Kinase Activity In Vivo

Hyper-Acetylation of Histone H3K56 Limits Break-Induced Replication by Inhibiting Extensive Repair Synthesis

Prodomain Removal Enables Neto to Stabilize Glutamate Receptors at the Neuromuscular Junction

Recent Selective Sweeps in North American Show Signatures of Soft Sweeps

Identification and Functional Analysis of Healing Regulators in

A Multi-Megabase Copy Number Gain Causes Maternal Transmission Ratio Distortion on Mouse Chromosome 2

Drosophila Casein Kinase I Alpha Regulates Homolog Pairing and Genome Organization by Modulating Condensin II Subunit Cap-H2 Levels

The Hippo Pathway Regulates Homeostatic Growth of Stem Cell Niche Precursors in the Ovary

Perspective

32767

and Hyperdrive Mechanisms (in Mouse Meiosis)

Review

32767

Closing the Gap between Knowledge and Clinical Application: Challenges for Genomic Translation

Editorial

32767

2014 Reviewer Thank You

PLOS Genetics

2015 Číslo 2

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