PLOS Genetics - Číslo 8/2012


Advances in Quantitative Trait Analysis in Yeast


Chromosome Territories Meet a Condensin
It's All in the Timing: Too Much E2F Is a Bad Thing
CDK9 and H2B Monoubiquitination: A Well-Choreographed Dance

Research Article

Mutational Signatures of De-Differentiation in Functional Non-Coding Regions of Melanoma Genomes
Rescuing Alu: Recovery of Inserts Shows LINE-1 Preserves Alu Activity through A-Tail Expansion
Genetics and Regulatory Impact of Alternative Polyadenylation in Human B-Lymphoblastoid Cells
Fine-Mapping and Initial Characterization of QT Interval Loci in African Americans
Genome Patterns of Selection and Introgression of Haplotypes in Natural Populations of the House Mouse ()
A Combinatorial Amino Acid Code for RNA Recognition by Pentatricopeptide Repeat Proteins
Experimental Evolution of a Novel Sexually Antagonistic Allele
Variation of Contributes to Dog Breed Skull Diversity
, a Gene Involved in Axonal Pathfinding, Is Mutated in Patients with Kallmann Syndrome
A Single Origin for Nymphalid Butterfly Eyespots Followed by Widespread Loss of Associated Gene Expression
Cryptocephal, the ATF4, Is a Specific Coactivator for Ecdysone Receptor Isoform B2
Retrovolution: HIV–Driven Evolution of Cellular Genes and Improvement of Anticancer Drug Activation
The PARN Deadenylase Targets a Discrete Set of mRNAs for Decay and Regulates Cell Motility in Mouse Myoblasts
A Sexual Ornament in Chickens Is Affected by Pleiotropic Alleles at and , Selected during Domestication
Use of Allele-Specific FAIRE to Determine Functional Regulatory Polymorphism Using Large-Scale Genotyping Arrays
Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis
The Genetic Basis of Pollinator Adaptation in a Sexually Deceptive Orchid
Uncovering the Genome-Wide Transcriptional Responses of the Filamentous Fungus to Lignocellulose Using RNA Sequencing
Inheritance Beyond Plain Heritability: Variance-Controlling Genes in
The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits
Reprogramming to Pluripotency Can Conceal Somatic Cell Chromosomal Instability
Condensin II Promotes the Formation of Chromosome Territories by Inducing Axial Compaction of Polyploid Interphase Chromosomes
PTEN Negatively Regulates MAPK Signaling during Vulval Development
A Dynamic Response Regulator Protein Modulates G-Protein–Dependent Polarity in the Bacterium
Population Genomics of the Facultatively Mutualistic Bacteria and
Components of a Fanconi-Like Pathway Control Pso2-Independent DNA Interstrand Crosslink Repair in Yeast
Polysome Profiling in Liver Identifies Dynamic Regulation of Endoplasmic Reticulum Translatome by Obesity and Fasting
Stromal Liver Kinase B1 [STK11] Signaling Loss Induces Oviductal Adenomas and Endometrial Cancer by Activating Mammalian Target of Rapamycin Complex 1
Reprogramming of H3K27me3 Is Critical for Acquisition of Pluripotency from Cultured Tissues
Transgene Induced Co-Suppression during Vegetative Growth in
Hox and Sex-Determination Genes Control Segment Elimination through EGFR and Activity
A Quantitative Comparison of the Similarity between Genes and Geography in Worldwide Human Populations
Minibrain/Dyrk1a Regulates Food Intake through the Sir2-FOXO-sNPF/NPY Pathway in and Mammals
Comparative Analysis of Regulatory Elements between and by Genome-Wide Transcription Start Site Profiling
Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome
S Phase–Coupled E2f1 Destruction Ensures Homeostasis in Proliferating Tissues
Cell-Nonautonomous Signaling of FOXO/DAF-16 to the Stem Cells of
The Mi-2 Chromatin-Remodeling Factor Regulates Higher-Order Chromatin Structure and Cohesin Dynamics
Comparative Analysis of the Genomes of Two Field Isolates of the Rice Blast Fungus
Role of Mex67-Mtr2 in the Nuclear Export of 40S Pre-Ribosomes
Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program
HAL-2 Promotes Homologous Pairing during Meiosis by Antagonizing Inhibitory Effects of Synaptonemal Complex Precursors
SLX-1 Is Required for Maintaining Genomic Integrity and Promoting Meiotic Noncrossovers in the Germline
Phylogenetic and Transcriptomic Analysis of Chemosensory Receptors in a Pair of Divergent Ant Species Reveals Sex-Specific Signatures of Odor Coding
Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency–Associated Developmental Defects by Preventing Matriptase Activation
Dissecting the Gene Network of Dietary Restriction to Identify Evolutionarily Conserved Pathways and New Functional Genes
Identification of Human Proteins That Modify Misfolding and Proteotoxicity of Pathogenic Ataxin-1
and Link Transcription of Phospholipid Biosynthetic Genes to ER Stress and the UPR
Rare Copy Number Variations in Adults with Tetralogy of Fallot Implicate Novel Risk Gene Pathways
Ccdc94 Protects Cells from Ionizing Radiation by Inhibiting the Expression of
NOL11, Implicated in the Pathogenesis of North American Indian Childhood Cirrhosis, Is Required for Pre-rRNA Transcription and Processing
Human Developmental Enhancers Conserved between Deuterostomes and Protostomes
A Luminal Glycoprotein Drives Dose-Dependent Diameter Expansion of the Hindgut Tube
Melanophore Migration and Survival during Zebrafish Adult Pigment Stripe Development Require the Immunoglobulin Superfamily Adhesion Molecule Igsf11
Dynamic Distribution of Linker Histone H1.5 in Cellular Differentiation
Combining Comparative Proteomics and Molecular Genetics Uncovers Regulators of Synaptic and Axonal Stability and Degeneration
Chemical Genetics Reveals a Specific Requirement for Cdk2 Activity in the DNA Damage Response and Identifies Nbs1 as a Cdk2 Substrate in Human Cells
Experimental Relocation of the Mitochondrial Gene to the Nucleus Reveals Forces Underlying Mitochondrial Genome Evolution
Rates of Gyrase Supercoiling and Transcription Elongation Control Supercoil Density in a Bacterial Chromosome
Mutations in a P-Type ATPase Gene Cause Axonal Degeneration
A General G1/S-Phase Cell-Cycle Control Module in the Flowering Plant
Multiple Roles and Interactions of and in Development of the Respiratory System
UNC-40/DCC, SAX-3/Robo, and VAB-1/Eph Polarize F-Actin during Embryonic Morphogenesis by Regulating the WAVE/SCAR Actin Nucleation Complex
Epigenetic Remodeling of Meiotic Crossover Frequency in DNA Methyltransferase Mutants
Modulating the Strength and Threshold of NOTCH Oncogenic Signals by
Loss of Axonal Mitochondria Promotes Tau-Mediated Neurodegeneration and Alzheimer's Disease–Related Tau Phosphorylation Via PAR-1
Acetyl-CoA-Carboxylase Sustains a Fatty Acid–Dependent Remote Signal to Waterproof the Respiratory System
ATXN2-CAG42 Sequesters PABPC1 into Insolubility and Induces FBXW8 in Cerebellum of Old Ataxic Knock-In Mice
Cohesin Rings Devoid of Scc3 and Pds5 Maintain Their Stable Association with the DNA
The MicroRNA Inhibits Calcium Signaling by Targeting the TIR-1/Sarm1 Adaptor Protein to Control Stochastic L/R Neuronal Asymmetry in
Rapid-Throughput Skeletal Phenotyping of 100 Knockout Mice Identifies 9 New Genes That Determine Bone Strength
The Genes Define Unique Classes of Two-Partner Secretion and Contact Dependent Growth Inhibition Systems

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