PLOS Genetics - Číslo 2/2012

Perspective

32767

Upsetting the Dogma: Germline Selection in Human Males

32767

Diced Triplets Expose Neurons to RISC

32767

The Williams-Beuren Syndrome—A Window into Genetic Variants Leading to the Development of Cardiovascular Disease

Research Article

32767

A Strong Deletion Bias in Nonallelic Gene Conversion

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The Dynamics and Prognostic Potential of DNA Methylation Changes at Stem Cell Gene Loci in Women's Cancer

32767

A Regulatory Network for Coordinated Flower Maturation

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Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes

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The Empirical Power of Rare Variant Association Methods: Results from Sanger Sequencing in 1,998 Individuals

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Systematic Detection of Epistatic Interactions Based on Allele Pair Frequencies

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Familial Identification: Population Structure and Relationship Distinguishability

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Raf1 Is a DCAF for the Rik1 DDB1-Like Protein and Has Separable Roles in siRNA Generation and Chromatin Modification

32767

Loss of Function of the Cik1/Kar3 Motor Complex Results in Chromosomes with Syntelic Attachment That Are Sensed by the Tension Checkpoint

32767

Computational Prediction and Molecular Characterization of an Oomycete Effector and the Cognate Resistance Gene

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GTPase Activity and Neuronal Toxicity of Parkinson's Disease–Associated LRRK2 Is Regulated by ArfGAP1

32767

The Role of Glypicans in Wnt Inhibitory Factor-1 Activity and the Structural Basis of Wif1's Effects on Wnt and Hedgehog Signaling

32767

Evaluation of the Role of Functional Constraints on the Integrity of an Ultraconserved Region in the Genus

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Neurophysiological Defects and Neuronal Gene Deregulation in Mutants

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Genetic and Functional Analyses of Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders

32767

Negative Supercoiling Creates Single-Stranded Patches of DNA That Are Substrates for AID–Mediated Mutagenesis

32767

Rewiring of PDZ Domain-Ligand Interaction Network Contributed to Eukaryotic Evolution

32767

The Eph Receptor Activates NCK and N-WASP, and Inhibits Ena/VASP to Regulate Growth Cone Dynamics during Axon Guidance

32767

Repression of a Potassium Channel by Nuclear Hormone Receptor and TGF-β Signaling Modulates Insulin Signaling in

32767

The Retrohoming of Linear Group II Intron RNAs in Occurs by Both DNA Ligase 4–Dependent and –Independent Mechanisms

32767

Cell Lineage Analysis of the Mammalian Female Germline

32767

Nondisjunction of a Single Chromosome Leads to Breakage and Activation of DNA Damage Checkpoint in G2

32767

Discovery of a Modified Tetrapolar Sexual Cycle in and the Evolution of in the Species Complex

32767

Positive Selection for New Disease Mutations in the Human Germline: Evidence from the Heritable Cancer Syndrome Multiple Endocrine Neoplasia Type 2B

32767

The Origin and Nature of Tightly Clustered Deletions in Precursor B-Cell Acute Lymphoblastic Leukemia Support a Model of Multiclonal Evolution

32767

Genome-Wide Association Study in East Asians Identifies Novel Susceptibility Loci for Breast Cancer

32767

Mixed Effects Modeling of Proliferation Rates in Cell-Based Models: Consequence for Pharmacogenomics and Cancer

32767

Reduction of NADPH-Oxidase Activity Ameliorates the Cardiovascular Phenotype in a Mouse Model of Williams-Beuren Syndrome

32767

Genome-Wide Association Study Identifies Chromosome 10q24.32 Variants Associated with Arsenic Metabolism and Toxicity Phenotypes in Bangladesh

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Structural Basis of Transcriptional Gene Silencing Mediated by MOM1

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Genomic Restructuring in the Tasmanian Devil Facial Tumour: Chromosome Painting and Gene Mapping Provide Clues to Evolution of a Transmissible Tumour

32767

Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations

32767

Contrasting Properties of Gene-Specific Regulatory, Coding, and Copy Number Mutations in : Frequency, Effects, and Dominance

32767

Ultrafast Evolution and Loss of CRISPRs Following a Host Shift in a Novel Wildlife Pathogen,

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Sequestration of Highly Expressed mRNAs in Cytoplasmic Granules, P-Bodies, and Stress Granules Enhances Cell Viability

32767

Phosphorylation of Chromosome Core Components May Serve as Axis Marks for the Status of Chromosomal Events during Mammalian Meiosis

32767

Psoriasis Patients Are Enriched for Genetic Variants That Protect against HIV-1 Disease

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A Pathogenic Mechanism in Huntington's Disease Involves Small CAG-Repeated RNAs with Neurotoxic Activity

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The Mitochondrial Chaperone Protein TRAP1 Mitigates α-Synuclein Toxicity

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Homeobox Genes Critically Regulate Embryo Implantation by Controlling Paracrine Signaling between Uterine Stroma and Epithelium

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Developmental Transcriptional Networks Are Required to Maintain Neuronal Subtype Identity in the Mature Nervous System

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Down-Regulating Sphingolipid Synthesis Increases Yeast Lifespan

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Gene Expression and Stress Response Mediated by the Epigenetic Regulation of a Transposable Element Small RNA

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Loss of Tgif Function Causes Holoprosencephaly by Disrupting the Shh Signaling Pathway

32767

Association of a Functional Variant in the Wnt Co-Receptor with Early Onset Ileal Crohn's Disease

PLOS Genetics

2012 Číslo 2

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