PLOS Genetics - Číslo 12/2011

Perspective

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An Anti-Checkpoint Activity for Rif1

Interview

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The Connection between Space and Thinking: An Interview with Rafael Viñoly

Research Article

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An Assessment of the Individual and Collective Effects of Variants on Height Using Twins and a Developmentally Informative Study Design
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Hierarchical Generalized Linear Models for Multiple Groups of Rare and Common Variants: Jointly Estimating Group and Individual-Variant Effects
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Autosomal Recessive Dilated Cardiomyopathy due to Mutations Results from Abnormal Dystroglycan O-Mannosylation
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SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen
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The RNA Silencing Enzyme RNA Polymerase V Is Required for Plant Immunity
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The FGFR4-G388R Polymorphism Promotes Mitochondrial STAT3 Serine Phosphorylation to Facilitate Pituitary Growth Hormone Cell Tumorigenesis
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Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals
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The Fission Yeast Stress-Responsive MAPK Pathway Promotes Meiosis via the Phosphorylation of Pol II CTD in Response to Environmental and Feedback Cues
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Integrating Genome-Wide Genetic Variations and Monocyte Expression Data Reveals -Regulated Gene Modules in Humans
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Repetitive Elements May Comprise Over Two-Thirds of the Human Genome
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A Novel Checkpoint and RPA Inhibitory Pathway Regulated by Rif1
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The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved
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Ancestral Components of Admixed Genomes in a Mexican Cohort
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A High-Resolution Whole-Genome Map of Key Chromatin Modifications in the Adult
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A Densely Interconnected Genome-Wide Network of MicroRNAs and Oncogenic Pathways Revealed Using Gene Expression Signatures
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A Functional Phylogenomic View of the Seed Plants
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Histone H3K9 Trimethylase Eggless Controls Germline Stem Cell Maintenance and Differentiation
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Ribosomal Protein Mutants Control Tissue Growth Non-Autonomously via Effects on the Prothoracic Gland and Ecdysone
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, , and Are Required to Activate or Delimit the Spread of the Transcriptional Response to Epidermal Wounds in
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Mechanisms Establishing TLR4-Responsive Activation States of Inflammatory Response Genes
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Candidate Gene Screen in the Red Flour Beetle Reveals as Ancient Regulator of Anterior Median Head and Central Complex Development
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Charcot-Marie-Tooth–Linked Mutant GARS Is Toxic to Peripheral Neurons Independent of Wild-Type GARS Levels
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Targeted Proteolysis of Plectin Isoform 1a Accounts for Hemidesmosome Dysfunction in Mice Mimicking the Dominant Skin Blistering Disease EBS-Ogna
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Target Site Recognition by a Diversity-Generating Retroelement
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Widespread Cotranslational Formation of Protein Complexes
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A Population Genetics-Phylogenetics Approach to Inferring Natural Selection in Coding Sequences
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Genomes Reveal Transition of Bacteria from Aquatic to Terrestrial Environments
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A Complex Genomic Rearrangement Involving the Locus Causes Dermal Hyperpigmentation in the Chicken
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Plasticity of BRCA2 Function in Homologous Recombination: Genetic Interactions of the PALB2 and DNA Binding Domains
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Transcription Is Required to Establish Maternal Imprinting at the Prader-Willi Syndrome and Angelman Syndrome Locus
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Substitutions in the Amino-Terminal Tail of Neurospora Histone H3 Have Varied Effects on DNA Methylation
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MAPK/ERK Signaling Regulates Insulin Sensitivity to Control Glucose Metabolism in
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A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap
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Genome Instability and Transcription Elongation Impairment in Human Cells Depleted of THO/TREX
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Genome-Wide Meta-Analysis of Five Asian Cohorts Identifies as a Susceptibility Locus for Corneal Astigmatism
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HIF-1 Regulates Iron Homeostasis in by Activation and Inhibition of Genes Involved in Iron Uptake and Storage
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Age-Related Neuronal Degeneration: Complementary Roles of Nucleotide Excision Repair and Transcription-Coupled Repair in Preventing Neuropathology
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Ror2 Enhances Polarity and Directional Migration of Primordial Germ Cells
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DNA Methylation of the Gonadal Aromatase () Promoter Is Involved in Temperature-Dependent Sex Ratio Shifts in the European Sea Bass
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A Genetic Screening Strategy Identifies Novel Regulators of the Proteostasis Network
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Interspecific Sex in Grass Smuts and the Genetic Diversity of Their Pheromone-Receptor System
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The Synthetic Multivulva Genes Prevent Ras Pathway Activation by Tightly Repressing Global Ectopic Expression of EGF
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Mining the Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol
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Identification of a Genomic Reservoir for New Genes in Primate Genomes
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Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types
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Identification of Evolutionarily Conserved Exons as Regulated Targets for the Splicing Activator Tra2β in Development
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Acute Multiple Organ Failure in Adult Mice Deleted for the Developmental Regulator Wt1
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The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate

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