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PLOS Genetics - Číslo 12/2011

Research Article

32767

An Assessment of the Individual and Collective Effects of Variants on Height Using Twins and a Developmentally Informative Study Design

Widespread Cotranslational Formation of Protein Complexes

Genomes Reveal Transition of Bacteria from Aquatic to Terrestrial Environments

A Complex Genomic Rearrangement Involving the Locus Causes Dermal Hyperpigmentation in the Chicken

Plasticity of BRCA2 Function in Homologous Recombination: Genetic Interactions of the PALB2 and DNA Binding Domains

Transcription Is Required to Establish Maternal Imprinting at the Prader-Willi Syndrome and Angelman Syndrome Locus

Substitutions in the Amino-Terminal Tail of Neurospora Histone H3 Have Varied Effects on DNA Methylation

MAPK/ERK Signaling Regulates Insulin Sensitivity to Control Glucose Metabolism in

A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap

Genome Instability and Transcription Elongation Impairment in Human Cells Depleted of THO/TREX

Genome-Wide Meta-Analysis of Five Asian Cohorts Identifies as a Susceptibility Locus for Corneal Astigmatism

A Population Genetics-Phylogenetics Approach to Inferring Natural Selection in Coding Sequences

HIF-1 Regulates Iron Homeostasis in by Activation and Inhibition of Genes Involved in Iron Uptake and Storage

Ror2 Enhances Polarity and Directional Migration of Primordial Germ Cells

DNA Methylation of the Gonadal Aromatase () Promoter Is Involved in Temperature-Dependent Sex Ratio Shifts in the European Sea Bass

A Genetic Screening Strategy Identifies Novel Regulators of the Proteostasis Network

Interspecific Sex in Grass Smuts and the Genetic Diversity of Their Pheromone-Receptor System

The Synthetic Multivulva Genes Prevent Ras Pathway Activation by Tightly Repressing Global Ectopic Expression of EGF

Mining the Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol

Identification of a Genomic Reservoir for New Genes in Primate Genomes

Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types

Identification of Evolutionarily Conserved Exons as Regulated Targets for the Splicing Activator Tra2β in Development

Acute Multiple Organ Failure in Adult Mice Deleted for the Developmental Regulator Wt1

Age-Related Neuronal Degeneration: Complementary Roles of Nucleotide Excision Repair and Transcription-Coupled Repair in Preventing Neuropathology

Target Site Recognition by a Diversity-Generating Retroelement

Ancestral Components of Admixed Genomes in a Mexican Cohort

Targeted Proteolysis of Plectin Isoform 1a Accounts for Hemidesmosome Dysfunction in Mice Mimicking the Dominant Skin Blistering Disease EBS-Ogna

Autosomal Recessive Dilated Cardiomyopathy due to Mutations Results from Abnormal Dystroglycan O-Mannosylation

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen

The RNA Silencing Enzyme RNA Polymerase V Is Required for Plant Immunity

The FGFR4-G388R Polymorphism Promotes Mitochondrial STAT3 Serine Phosphorylation to Facilitate Pituitary Growth Hormone Cell Tumorigenesis

Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals

The Fission Yeast Stress-Responsive MAPK Pathway Promotes Meiosis via the Phosphorylation of Pol II CTD in Response to Environmental and Feedback Cues

Integrating Genome-Wide Genetic Variations and Monocyte Expression Data Reveals -Regulated Gene Modules in Humans

Repetitive Elements May Comprise Over Two-Thirds of the Human Genome

A Novel Checkpoint and RPA Inhibitory Pathway Regulated by Rif1

Hierarchical Generalized Linear Models for Multiple Groups of Rare and Common Variants: Jointly Estimating Group and Individual-Variant Effects

The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved

A High-Resolution Whole-Genome Map of Key Chromatin Modifications in the Adult

A Densely Interconnected Genome-Wide Network of MicroRNAs and Oncogenic Pathways Revealed Using Gene Expression Signatures

A Functional Phylogenomic View of the Seed Plants

Histone H3K9 Trimethylase Eggless Controls Germline Stem Cell Maintenance and Differentiation

Ribosomal Protein Mutants Control Tissue Growth Non-Autonomously via Effects on the Prothoracic Gland and Ecdysone

, , and Are Required to Activate or Delimit the Spread of the Transcriptional Response to Epidermal Wounds in

Mechanisms Establishing TLR4-Responsive Activation States of Inflammatory Response Genes

Candidate Gene Screen in the Red Flour Beetle Reveals as Ancient Regulator of Anterior Median Head and Central Complex Development

Charcot-Marie-Tooth–Linked Mutant GARS Is Toxic to Peripheral Neurons Independent of Wild-Type GARS Levels

The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate

Interview

32767

The Connection between Space and Thinking: An Interview with Rafael Viñoly

Perspective

32767

An Anti-Checkpoint Activity for Rif1

PLOS Genetics

2011 Číslo 12

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