Independent validation of experimental results requires timely and unrestricted access to animal models and reagents

English version

Autoři: Cassandra R. Diegel ^aff001; Steven Hann ^aff002; Ugur M. Ayturk ^aff002; Jennifer C. W. Hu ^aff002; Kyung-eun Lim ^aff004; Casey J. Droscha ^aff001; Zachary B. Madaj ^aff005; Gabrielle E. Foxa ^aff001; Isaac Izaguirre ^aff001; ^aff006; Alexander G. Robling ^aff004; Matthew L. Warman ^aff002; Bart O. Williams ^aff001
Působiště autorů: Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America ^aff001; Orthopedic Research Labs, Boston Children’s Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America ^aff002; Musculoskeletal Integrity Program, Hospital for Special Surgery Research Institute, New York, New York, United States of America ^aff003; Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America ^aff004; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, Michigan, United States of America ^aff005; Vivarium and Transgenics Core, Van Andel Institute, Grand Rapids, Michigan, United States of America ^aff006
Vyšlo v časopise: Independent validation of experimental results requires timely and unrestricted access to animal models and reagents. PLoS Genet 16(6): e32767. doi:10.1371/journal.pgen.1008940
Kategorie: Formal Comment
doi: https://doi.org/10.1371/journal.pgen.1008940

Zdroje

1. Diegel CR, Hann S, Ayturk UM, Hu JCW, Lim KE, et al. (2020) An osteocalcin-deficient mouse strain without endocrine abnormalities. PLoS Genet 16: e1008361. doi: 10.1371/journal.pgen.1008361 32463812

2. Ducy P, Desbois C, Boyce B, Pinero G, Story B, et al. (1996) Increased bone formation in osteocalcin-deficient mice. Nature 382 : 448–452. doi: 10.1038/382448a0 8684484

3. Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, et al. (2007) Endocrine regulation of energy metabolism by the skeleton. Cell 130 : 456–469. doi: 10.1016/j.cell.2007.05.047 17693256

4. Oury F, Sumara G, Sumara O, Ferron M, Chang H, et al. (2011) Endocrine regulation of male fertility by the skeleton. Cell 144 : 796–809. doi: 10.1016/j.cell.2011.02.004 21333348

5. Moriishi T, Ozasa R, Ishimoto T, Nakano T, Hasegawa T, et al. (2020) Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass. PLoS Genet 16: e1008586. doi: 10.1371/journal.pgen.1008586 32463816

6. Lambert LJ, Challa AK, Niu A, Zhou L, Tucholski J, et al. (2016) Increased trabecular bone and improved biomechanics in an osteocalcin-null rat model created by CRISPR/Cas9 technology. Dis Model Mech 9 : 1169–1179. doi: 10.1242/dmm.025247 27483347

7. Fowlkes JL, Clay Bunn R, Kalaitzoglou E, Ray P, Popescu I, et al. (2020) Postnatal loss of the insulin receptor in osteoprogenitor cells does not impart a metabolic phenotype. Sci Rep 10 : 8842. doi: 10.1038/s41598-020-65717-3 32483283

8. von Herrath M, Pagni PP, Grove K, Christoffersson G, Tang-Christensen M, et al. (2019) Case Reports of Pre-clinical Replication Studies in Metabolism and Diabetes. Cell Metab 29 : 795–802. doi: 10.1016/j.cmet.2019.02.004 30879984

9. Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, et al. (2008) Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell 135 : 825–837. doi: 10.1016/j.cell.2008.09.059 19041748

10. Kode A, Obri A, Paone R, Kousteni S, Ducy P, et al. (2014) Lrp5 regulation of bone mass and serotonin synthesis in the gut. Nat Med 20 : 1228–1229. doi: 10.1038/nm.3698 25375916

11. Cui Y, Niziolek PJ, MacDonald BT, Zylstra CR, Alenina N, et al. (2011) Lrp5 functions in bone to regulate bone mass. Nat Med 17 : 684–691. doi: 10.1038/nm.2388 21602802

12. Cui Y, Niziolek PJ, MacDonald BT, Alenina N, Matthes S, et al. (2014) Reply to Lrp5 regulation of bone mass and gut serotonin synthesis. Nat Med 20 : 1229–1230. doi: 10.1038/nm.3697 25375917

13. Lee GS, Simpson C, Sun BH, Yao C, Foer D, et al. (2014) Measurement of plasma, serum, and platelet serotonin in individuals with high bone mass and mutations in LRP5. J Bone Miner Res 29 : 976–981. doi: 10.1002/jbmr.2086 24038240

14. National Academies of Sciences Engineering and Medicine (U.S.). Committee on Responsible Science, Committee on Science Engineering Medicine and Public Policy (U.S.) (2017) Fostering integrity in research. 1 online resource (1 PDF file (xv, 307 pages)) p.

Článek Duplication and divergence of the retrovirus restriction gene Fv1 in Mus caroli allows protection from multiple retroviruses

Článek Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase

Článek Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosis

Článek Regulation of olfactory-based sex behaviors in the silkworm by genes in the sex-determination cascade

Článek Osteocalcin promotes bone mineralization but is not a hormone

Článek A conserved, N-terminal tyrosine signal directs Ras for inhibition by Rabex-5

Článek Integrins regulate epithelial cell shape by controlling the architecture and mechanical properties of basal actomyosin networks

Článek Cancer-associated mutations in the iron-sulfur domain of FANCJ affect G-quadruplex metabolism

Článek NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure

Článek Pax6 organizes the anterior eye segment by guiding two distinct neural crest waves

Článek Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology

Článek Alpha- and beta-adrenergic octopamine receptors in muscle and heart are required for Drosophila exercise adaptations